aztreonam has been researched along with Complication, Postoperative in 26 studies
Aztreonam: A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
aztreonam : A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 mg/kg intravenously every eight hours), each with clindamycin (600 mg intravenously every six hours), was performed in 119 patients with endometritis after cesarean section." | 9.05 | Aztreonam versus gentamicin, each with clindamycin, in the treatment of endometritis. ( Blanco, JD; Gibbs, RS; Lipscomb, KA; St Clair, PJ, 1985) |
| "5 mg/kg intravenously every eight hours), each with clindamycin (600 mg intravenously every six hours), was performed in 119 patients with endometritis after cesarean section." | 5.05 | Aztreonam versus gentamicin, each with clindamycin, in the treatment of endometritis. ( Blanco, JD; Gibbs, RS; Lipscomb, KA; St Clair, PJ, 1985) |
| "Endomyometritis is the most common complication associated with cesarean delivery." | 3.76 | Pathophysiology and management of postcesarean endomyometritis. ( Duff, P, 1986) |
| "Urinary tract infections (1 case) and respiratory tract infections (2 cases) were observed only in group B: the rate was found to be 11." | 2.66 | Systemic perioperative prophylaxis in elective oncological colorectal surgery: cefotetan versus clindamicin plus aztreonam. ( Bellantone, R; Bossola, M; Crucitti, F; Doglietto, GB; Pacelli, F; Ratto, C; Sofo, L, 1988) |
| "We report on one rare case of recurrent pseudomembranous colitis associated with antibiotic treatment with Aztreonam." | 2.38 | [Antibiotic-associated pseudomembranous colitis--a case report with review of the literature]. ( Hegelmaier, C; Hütig, HB; Kalbheim, HJ, 1991) |
| "Aztreonam has a high affinity for the protein-binding protein 3 (PBP-3) of aerobic gram-negative bacteria." | 2.38 | How and why aztreonam works. ( Rittenbury, MS, 1990) |
| "The incidence of surgical wound infections was 2." | 1.28 | [Antibiotic prophylaxis with aztreonam in general surgery]. ( Balcet, F; Bossotti, M; Martino, F; Polastri, R; Vasario, U, 1992) |
| "Aztreonam (AZT) was administered to immature infants, neonates and infants for preclinical and clinical studies." | 1.28 | [Preclinical and clinical studies on aztreonam in pediatric surgery]. ( Kimura, K; Miyano, T; Shimomura, H, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (46.15) | 18.7374 |
| 1990's | 10 (38.46) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Camilleri, E | 1 |
| Maggini, N | 1 |
| Piccica, M | 1 |
| Botta, A | 1 |
| Poli, D | 1 |
| Blandino, G | 1 |
| Lo Bue, A | 1 |
| Motta, RM | 1 |
| Di Cataldo, A | 1 |
| Tempera, G | 1 |
| Rodolico, G | 1 |
| Wong, GK | 1 |
| Poon, WS | 1 |
| Lyon, D | 1 |
| Wai, S | 1 |
| Castelao, AM | 1 |
| Soto, K | 1 |
| Grinyó, JM | 1 |
| Gilvernet, S | 1 |
| Serón, D | 1 |
| Torras, J | 1 |
| Riera, L | 1 |
| Cruzado, JM | 1 |
| Alsina, J | 1 |
| Gilad, J | 1 |
| Borer, A | 1 |
| Peled, N | 1 |
| Riesenberg, K | 1 |
| Tager, S | 1 |
| Appelbaum, A | 1 |
| Schlaeffer, F | 1 |
| Raad, I | 1 |
| Hachem, R | 1 |
| Hanna, H | 1 |
| Abi-Said, D | 1 |
| Bivins, C | 1 |
| Walsh, G | 1 |
| Thornby, J | 1 |
| Whimbey, E | 1 |
| Huaringa, A | 1 |
| Sukumaran, A | 1 |
| Martino, F | 1 |
| Bossotti, M | 1 |
| Polastri, R | 1 |
| Balcet, F | 1 |
| Vasario, U | 1 |
| Hegelmaier, C | 1 |
| Hütig, HB | 1 |
| Kalbheim, HJ | 1 |
| Mozzillo, N | 2 |
| Formato, A | 2 |
| Quarto, G | 1 |
| Ottaviano, A | 2 |
| Romano, A | 2 |
| Morris, DL | 1 |
| Wilson, SR | 1 |
| Pain, J | 1 |
| Edwardson, KF | 1 |
| Jones, J | 1 |
| Strachan, C | 1 |
| Slack, R | 1 |
| Chimura, T | 1 |
| Saito, N | 1 |
| Morisaki, N | 1 |
| Funayama, T | 1 |
| Rittenbury, MS | 1 |
| Nichols, RL | 1 |
| Shimomura, H | 1 |
| Miyano, T | 1 |
| Kimura, K | 1 |
| Yura, J | 1 |
| Suzuki, T | 1 |
| Hashimoto, T | 1 |
| Nakamura, T | 1 |
| Shimizu, Y | 1 |
| Minami, M | 1 |
| Kamiya, Y | 1 |
| Narita, H | 1 |
| Tsuruga, N | 1 |
| DiPiro, JT | 1 |
| Bowden, TA | 1 |
| Giannoni, R | 1 |
| Legramandi, C | 1 |
| Fonte, A | 1 |
| Heimdahl, A | 1 |
| Kager, L | 1 |
| Nord, CE | 1 |
| Bellantone, R | 1 |
| Pacelli, F | 1 |
| Sofo, L | 1 |
| Doglietto, GB | 1 |
| Bossola, M | 1 |
| Ratto, C | 1 |
| Crucitti, F | 1 |
| Millar, MR | 1 |
| Inglis, T | 1 |
| Ewing, R | 1 |
| Clark, P | 1 |
| Williams, RE | 1 |
| Lacey, RW | 1 |
| Craus, W | 1 |
| Dalet, F | 1 |
| del Río, G | 1 |
| Rabinad, E | 1 |
| Duff, P | 1 |
| Donati, PA | 1 |
| Gallicchio, B | 1 |
| Maiuri, F | 1 |
| Gangemi, M | 1 |
| D'Andrea, F | 1 |
| Hatase, T | 1 |
| Katabuchi, H | 1 |
| Watanabe, H | 1 |
| Umezu, J | 1 |
| Yakushiji, M | 1 |
| Kato, T | 1 |
| Gibbs, RS | 1 |
| Blanco, JD | 1 |
| Lipscomb, KA | 1 |
| St Clair, PJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment Utility of Postpartum Antibiotics in Chorioamnionitis[NCT01585129] | Phase 4 | 80 participants (Actual) | Interventional | 2010-09-30 | Terminated (stopped due to Futility in patient enrollment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
This is the duration of hospital stay (in days) after their cesarean delivery. (NCT01585129)
Timeframe: Up to 7 Days
| Intervention | days (Mean) |
|---|---|
| Postpartum Antibiotics | 4 |
| No Postpartum Antibiotics | 4 |
Endometritis is defined as uterine infection and is diagnosed by maternal temp > 38.0C on two occasions over a 4 hour period or any temp > 39.0C after delivery > 12 hours after delivery. Endometritis will be managed per currently accepted endometritis protocol - (Amp 2 gQ6, Gentamicin 5 mg/kg q24, Clindamycin 900 mg q8). (NCT01585129)
Timeframe: 7 days post-partum
| Intervention | Participants (Count of Participants) |
|---|---|
| Postpartum Antibiotics | 4 |
| No Postpartum Antibiotics | 3 |
Infection related complications will include common complications attributed to infections there are not the primary outcome (endometritis). This will include infections of the wound and pelvic abscesses. (NCT01585129)
Timeframe: 7 days post-partum
| Intervention | Participants (Count of Participants) |
|---|---|
| Postpartum Antibiotics | 7 |
| No Postpartum Antibiotics | 2 |
5 reviews available for aztreonam and Complication, Postoperative
| Article | Year |
|---|---|
Hospital-acquired brevundimonas vesicularis septicaemia following open-heart surgery: case report and literature review.
Topics: Adult; Anti-Infective Agents; Aztreonam; Ciprofloxacin; Cross Infection; Female; Humans; Microbial S | 2000 |
[Antibiotic-associated pseudomembranous colitis--a case report with review of the literature].
Topics: Adenocarcinoma; Aged; Aztreonam; Colostomy; Enterocolitis, Pseudomembranous; Female; Humans; Hystere | 1991 |
How and why aztreonam works.
Topics: Aztreonam; Cross Infection; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Postoperati | 1990 |
A comparison of monobactam antibiotics in surgical infections.
Topics: Aminoglycosides; Anti-Bacterial Agents; Aztreonam; Bacteria; Bacterial Infections; Humans; Postopera | 1989 |
Pathophysiology and management of postcesarean endomyometritis.
Topics: Adult; Anti-Bacterial Agents; Aztreonam; Bacterial Infections; Cephalosporins; Cesarean Section; Cli | 1986 |
10 trials available for aztreonam and Complication, Postoperative
| Article | Year |
|---|---|
Cefepime vs. Ampicillin/Sulbactam and Aztreonam as antibiotic prophylaxis in neurosurgical patients with external ventricular drain: result of a prospective randomized controlled clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ampicillin; Antibiotic Prophylaxis; Aztreonam; Cefepime; | 2006 |
Prophylaxis of urinary tract infection in renal transplantation: comparison of three different protocols using ceftriaxone-cloxacillin, aztreonam-cloxacillin, or aztreonam-amoxycillin-clavulanic acid.
Topics: Adult; Amoxicillin; Aztreonam; Ceftriaxone; Cloxacillin; Drug Therapy, Combination; Female; Follow-U | 1995 |
Treatment of nosocomial postoperative pneumonia in cancer patients: a prospective randomized study.
Topics: Aged; Amikacin; Aztreonam; Chi-Square Distribution; Clindamycin; Cross Infection; Drug Therapy, Comb | 2001 |
To assess the efficacy of prophylaxis in digestive tract surgery using a predictive model of complication risk.
Topics: Aztreonam; Bacterial Infections; Chi-Square Distribution; Digestive System Diseases; Double-Blind Me | 1990 |
A comparison of aztreonam/metronidazole and cefotaxime/metronidazole in elective colorectal surgery: antimicrobial prophylaxis must include gram-positive cover.
Topics: Aztreonam; Bacterial Infections; Cefotaxime; Colon; Drug Therapy, Combination; Gram-Positive Bacteri | 1990 |
Systemic perioperative prophylaxis in elective oncological colorectal surgery: cefotetan versus clindamicin plus aztreonam.
Topics: Adult; Aged; Aged, 80 and over; Aztreonam; Cefotetan; Clindamycin; Colorectal Neoplasms; Female; Hum | 1988 |
Double-blind study comparing aztreonam with placebo for prophylaxis of infection following prostatic surgery.
Topics: Aztreonam; Bacteriuria; Clinical Trials as Topic; Double-Blind Method; Humans; Male; Postoperative C | 1987 |
Antibiotic prophylaxis in surgery ranked by patients' risk rates.
Topics: Aztreonam; Clindamycin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Gentamicins; Hu | 1987 |
Pathophysiology and management of postcesarean endomyometritis.
Topics: Adult; Anti-Bacterial Agents; Aztreonam; Bacterial Infections; Cephalosporins; Cesarean Section; Cli | 1986 |
Aztreonam versus gentamicin, each with clindamycin, in the treatment of endometritis.
Topics: Adult; Anti-Bacterial Agents; Aztreonam; Cesarean Section; Clindamycin; Clinical Trials as Topic; Dr | 1985 |
12 other studies available for aztreonam and Complication, Postoperative
| Article | Year |
|---|---|
A rare case of prothrombin time prolongation.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Aztreonam; Bacteremia; Blood Coagulation Disorders; Carc | 2021 |
Microbiological intraoperative results in short-term prophylaxis (aztreonam or gentamicin) in abdominal surgery.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Aztreonam; Bacteria; Biliary Tract Surgical Procedure | 1989 |
[Antibiotic prophylaxis with aztreonam in general surgery].
Topics: Adult; Aged; Aged, 80 and over; Aztreonam; Female; Humans; Male; Middle Aged; Postoperative Complica | 1992 |
[Influences of postoperative prophylaxis treatments on vaginal bacteria flora at hysterectomy].
Topics: Adult; Aztreonam; Bacteria; Bacterial Infections; Colony Count, Microbial; Female; Humans; Hysterect | 1990 |
Surgery-related infections: a challenge for the physician. Introduction.
Topics: Aminoglycosides; Anti-Bacterial Agents; Aztreonam; Bacterial Infections; Cross Infection; Drug Resis | 1990 |
[Preclinical and clinical studies on aztreonam in pediatric surgery].
Topics: Aztreonam; Bacterial Infections; Bile; Biliary Atresia; Female; Humans; Infant, Newborn; Infant, Pre | 1990 |
[Pharmacokinetics and clinical evaluation of aztreonam in pediatric surgery].
Topics: Aztreonam; Bacterial Infections; Bile; Biliary Atresia; Cholangitis; Female; Humans; Infant, Newborn | 1990 |
"Short-term" prophylaxis by aztreonam in prevention of post-operative infections in patients undergoing transurethral surgery.
Topics: Aztreonam; Humans; Postoperative Complications; Premedication; Urethra; Urinary Tract Infections; Ur | 1988 |
Alterations in the human oropharyngeal microflora related to therapy with aztreonam, moxalactam and ampicillin plus sulbactam.
Topics: Adult; Aged; Ampicillin; Aztreonam; Colon; Drug Combinations; Female; Gram-Negative Bacteria; Humans | 1986 |
[Aztreonam: prevention of bacteremia in urologic surgery in patients with urinary infection].
Topics: Adult; Aged; Aztreonam; Female; Gram-Negative Bacteria; Humans; Male; Middle Aged; Postoperative Com | 1988 |
[Clinical evaluation of aztreonam in the prevention and therapy of infections in patients subjected to neurosurgical intervention].
Topics: Adult; Aged; Aztreonam; Bacterial Infections; Child; Child, Preschool; Drug Administration Schedule; | 1987 |
[Clinical studies on aztreonam in infections in obstetrics and gynecology].
Topics: Adult; Aged; Aztreonam; Bacterial Infections; Drug Evaluation; Female; Humans; Infusions, Parenteral | 1985 |