aztreonam has been researched along with Benign Neoplasms in 24 studies
Aztreonam: A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
aztreonam : A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy and safety of piperacillin/tazobactam plus ceftazidime (PIPC/TAZ+CAZ) versus sulbactam/ampicillin plus aztreonam (SBT/ABPC+AZT) as empirical therapy for febrile neutropenia were assessed in children with hematologic disease and solid tumor." | 9.14 | Piperacillin/tazobactam plus ceftazidime versus sulbactam/ampicillin plus aztreonam as empirical therapy for fever in severely neutropenic pediatric patients. ( Iguchi, A; Kaneda, M; Kobayashi, R; Nakajima, M; Sato, T, 2009) |
| " In the present study, we chose aztreonam as the alternative to aminoglycoside in combination with piperacillin for neutropenic fever in pediatric patients and we evaluated its effectiveness." | 9.10 | Piperacillin plus aztreonam for treatment of neutropenic fever. ( Mayumi, M; Takeuchi, M; Tanizawa, A, 2003) |
| "The efficacy and safety of piperacillin/tazobactam plus ceftazidime (PIPC/TAZ+CAZ) versus sulbactam/ampicillin plus aztreonam (SBT/ABPC+AZT) as empirical therapy for febrile neutropenia were assessed in children with hematologic disease and solid tumor." | 5.14 | Piperacillin/tazobactam plus ceftazidime versus sulbactam/ampicillin plus aztreonam as empirical therapy for fever in severely neutropenic pediatric patients. ( Iguchi, A; Kaneda, M; Kobayashi, R; Nakajima, M; Sato, T, 2009) |
| " In the present study, we chose aztreonam as the alternative to aminoglycoside in combination with piperacillin for neutropenic fever in pediatric patients and we evaluated its effectiveness." | 5.10 | Piperacillin plus aztreonam for treatment of neutropenic fever. ( Mayumi, M; Takeuchi, M; Tanizawa, A, 2003) |
| " Thus, both the adverse prognostic effect of leukemia as an underlying disease and the poorer results obtained using aztreonam-containing regimens were evident only with certain outcome definitions." | 5.06 | The effect of different measures of outcome on the results of studies of empiric antibiotic therapy in febrile neutropenic patients. ( Elliott, CR; Pater, JL, 1988) |
| "The treatment of bacterial infections in neutropenic cancer patients presents a serious challenge to physicians." | 2.38 | Aztreonam in the prevention and treatment of infection in neutropenic cancer patients. ( Bodey, GP; Elting, L; Rolston, KV, 1990) |
| " The serum half-life ranged between 1." | 1.27 | Clinical pharmacokinetics of aztreonam in cancer patients. ( Bodey, GP; Fainstein, V; Ho, DH; Jones, PG; Pasternak, J; Swabb, EA, 1984) |
| "Eighteen patients with hematological malignancies received aztreonam in one of two dosing regimens, 1 or 2 g every 8 h for a total of 7 to 9 days." | 1.27 | Effect of aztreonam on throat and stool flora of cancer patients. ( Bodey, GP; Jones, PG; Rosenbaum, B; Swabb, EA, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (41.67) | 18.7374 |
| 1990's | 9 (37.50) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McCullough, BJ | 1 |
| Wiggins, LE | 1 |
| Richards, A | 1 |
| Klinker, K | 1 |
| Hiemenz, JW | 1 |
| Wingard, JR | 1 |
| Kobayashi, R | 1 |
| Sato, T | 1 |
| Nakajima, M | 1 |
| Kaneda, M | 1 |
| Iguchi, A | 1 |
| Fleming, DR | 1 |
| Ziegler, C | 1 |
| Baize, T | 1 |
| Mudd, L | 1 |
| Goldsmith, GH | 1 |
| Herzig, RH | 1 |
| Takeuchi, M | 1 |
| Tanizawa, A | 1 |
| Mayumi, M | 1 |
| Jones, PG | 3 |
| Bodey, GP | 8 |
| Swabb, EA | 2 |
| Ho, DH | 3 |
| Fainstein, V | 2 |
| Pasternak, J | 1 |
| Rosenbaum, B | 1 |
| Dholakia, N | 1 |
| Rolston, KV | 4 |
| LeBlanc, B | 1 |
| Streeter, H | 1 |
| Dvorak, T | 1 |
| Freifeld, AG | 1 |
| Rubenstein, EB | 1 |
| Rolston, K | 1 |
| Benjamin, RS | 1 |
| Loewy, J | 1 |
| Escalante, C | 1 |
| Manzullo, E | 1 |
| Hughes, P | 1 |
| Moreland, B | 1 |
| Fender, A | 1 |
| Kennedy, K | 1 |
| Raad, II | 1 |
| Whimbey, EE | 1 |
| Abi-Said, D | 2 |
| Hachem, RY | 1 |
| Pandya, RG | 1 |
| Ghaddar, HM | 1 |
| Karl, CL | 1 |
| Raad, I | 1 |
| Hachem, R | 1 |
| Hanna, H | 1 |
| Bivins, C | 1 |
| Walsh, G | 1 |
| Thornby, J | 1 |
| Whimbey, E | 1 |
| Huaringa, A | 1 |
| Sukumaran, A | 1 |
| Sakata, Y | 1 |
| Sawada, Y | 1 |
| Kuroe, K | 1 |
| Nakaji, S | 1 |
| Takami, H | 1 |
| Tsushima, K | 1 |
| Saito, S | 1 |
| Ogasawara, H | 1 |
| Shinagawa, H | 1 |
| Soma, N | 1 |
| Bodey, G | 1 |
| Reuben, A | 1 |
| Elting, L | 4 |
| Kantarjian, H | 1 |
| Keating, M | 1 |
| Hagemeister, F | 1 |
| Koller, C | 1 |
| Velasquez, W | 1 |
| Papadopoulos, N | 1 |
| Hirotsu, T | 1 |
| Akatsuka, J | 1 |
| Hoshi, Y | 1 |
| Uchiyama, H | 1 |
| Fujisawa, K | 1 |
| Kobayashi, N | 1 |
| Ishidoya, N | 1 |
| Ohira, M | 1 |
| Takayama, J | 1 |
| Ishida, Y | 1 |
| Spencer, RC | 1 |
| Taylor, AK | 1 |
| Winfield, DA | 1 |
| Natali, M | 1 |
| Tonini, G | 1 |
| Tufo, E | 1 |
| Leggio, M | 1 |
| Carassai, A | 1 |
| Lopez, M | 1 |
| Apice, G | 1 |
| Beneduce, G | 1 |
| Bruni, GS | 1 |
| D'Aprile, M | 1 |
| Perna, M | 1 |
| Silvestro, P | 1 |
| Villari, P | 1 |
| Pergola, M | 1 |
| Elliott, CR | 1 |
| Pater, JL | 1 |
| Casali, A | 1 |
| Ameglio, F | 1 |
| Gionfra, T | 1 |
| Tonachella, R | 1 |
| Paoletti, G | 1 |
| Gallo Curcio, C | 1 |
| Menichetti, F | 1 |
| Bucaneve, G | 1 |
| Patoia, L | 1 |
| Guerciolini, R | 1 |
| Minotti, V | 1 |
| Pauluzzi, S | 1 |
| Del Favero, A | 1 |
| Jones, P | 1 |
| Walters, RS | 1 |
2 reviews available for aztreonam and Benign Neoplasms
| Article | Year |
|---|---|
Infectious complications in the immunocompromised host. The antimicrobial armamentarium.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Aminoglycosides; Amphotericin B; Anti-Bacterial Agent | 1993 |
Aztreonam in the prevention and treatment of infection in neutropenic cancer patients.
Topics: Agranulocytosis; Aztreonam; Bacterial Infections; Drug Therapy, Combination; Gram-Negative Bacteria; | 1990 |
14 trials available for aztreonam and Benign Neoplasms
| Article | Year |
|---|---|
Piperacillin/tazobactam plus ceftazidime versus sulbactam/ampicillin plus aztreonam as empirical therapy for fever in severely neutropenic pediatric patients.
Topics: Adolescent; Ampicillin; Anti-Bacterial Agents; Aztreonam; beta-Lactams; Ceftazidime; Child; Child, P | 2009 |
Cefepime versus ticarcillin and clavulanate potassium and aztreonam for febrile neutropenia therapy in high-dose chemotherapy patients.
Topics: Adult; Aged; Anti-Bacterial Agents; Antineoplastic Agents; Aztreonam; Cefepime; Cephalosporins; Clav | 2003 |
Piperacillin plus aztreonam for treatment of neutropenic fever.
Topics: Adolescent; Anti-Bacterial Agents; Aztreonam; Bacterial Infections; Child; Child, Preschool; Drug Th | 2003 |
Outpatient treatment of febrile episodes in low-risk neutropenic patients with cancer.
Topics: Administration, Oral; Adolescent; Adult; Aged; Ambulatory Care; Aztreonam; Bacteremia; Bacterial Inf | 1993 |
A comparison of aztreonam plus vancomycin and imipenem plus vancomycin as initial therapy for febrile neutropenic cancer patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Aztreonam; Bacterial Infections; | 1996 |
Treatment of nosocomial postoperative pneumonia in cancer patients: a prospective randomized study.
Topics: Aged; Amikacin; Aztreonam; Chi-Square Distribution; Clindamycin; Cross Infection; Drug Therapy, Comb | 2001 |
[A randomized controlled study on imipenem/cilastatin sodium in comparison to aztreonam + lincomycin in treating severe infections in patients with malignant tumors or hematological diseases].
Topics: Adolescent; Adult; Aged; Aztreonam; Cilastatin; Drug Therapy, Combination; Female; Hematologic Disea | 1992 |
Comparison of two schedules of cefoperazone plus aztreonam in the treatment of neutropenic patients with fever.
Topics: Aztreonam; Bacterial Infections; Cefoperazone; Drug Administration Schedule; Drug Therapy, Combinati | 1991 |
[Clinical evaluation of aztreonam for infections accompanying febrile neutropenic children with hematologic disorders and solid tumors. A cooperative study].
Topics: Adolescent; Age Factors; Aztreonam; Bacterial Infections; Cefmetazole; Child; Child, Preschool; Drug | 1990 |
A comparative efficacy and safety study of teicoplanin plus aztreonam versus gentamicin plus piperacillin in haematology oncology patients with clinically diagnosed septicaemia.
Topics: Adult; Anti-Bacterial Agents; Aztreonam; Bacteria; Drug Therapy, Combination; Female; Gentamicins; G | 1990 |
The effect of different measures of outcome on the results of studies of empiric antibiotic therapy in febrile neutropenic patients.
Topics: Acute Disease; Agranulocytosis; Anti-Bacterial Agents; Aztreonam; Clinical Trials as Topic; Cloxacil | 1988 |
Amikacin plus ceftazidime versus amikacin plus piperacillin versus amikacin plus aztreonam in infections in neoplastic patients with granulocytopenia.
Topics: Adult; Agranulocytosis; Amikacin; Anti-Bacterial Agents; Aztreonam; Bacterial Infections; Ceftazidim | 1987 |
Aztreonam plus cefazolin: a double beta-lactam combination as empirical therapy in febrile cancer patients with or without granulocytopenia.
Topics: Agranulocytosis; Aztreonam; Bacterial Infections; Cefazolin; Ceftriaxone; Clinical Trials as Topic; | 1987 |
Aztreonam therapy in neutropenic patients with cancer.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Aztreonam; | 1986 |
8 other studies available for aztreonam and Benign Neoplasms
| Article | Year |
|---|---|
Aztreonam for febrile neutropenia in patients with beta-lactam allergy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Aztreonam; beta-Lactams; Chemothe | 2014 |
Clinical pharmacokinetics of aztreonam in cancer patients.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Aztreonam; Dose-Response Relationship, Drug; Half-Li | 1984 |
Effect of aztreonam on throat and stool flora of cancer patients.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Aztreonam; Bacteria, Aerobic; Bacteria, Anaerobic; B | 1984 |
In vitro activity of FK-037, a novel parenteral cephalosporin, against bacterial isolates from neutropenic cancer patients.
Topics: Aztreonam; Bacteria; Ceftazidime; Ceftizoxime; Humans; Microbial Sensitivity Tests; Neoplasms; Neutr | 1994 |
[Aztreonam and oxacillin in the treatment of febrile neutropenic patients with solid tumors].
Topics: Adult; Aged; Agranulocytosis; Aztreonam; Bacterial Infections; Female; Fever; Humans; Male; Middle A | 1989 |
[Bacterial infections in cancer patients without neutropenia. Comparison between 2 antibiotic combinations (aztreonam and oxacillin versus cefoxitin and tobramycin)].
Topics: Adult; Aged; Aztreonam; Bacterial Infections; Cefoxitin; Drug Evaluation; Drug Therapy, Combination; | 1989 |
Survey of antibiotic susceptibility among gram-negative bacilli at a cancer hospital.
Topics: Anti-Bacterial Agents; Aztreonam; Cefoperazone; Ceftazidime; Ciprofloxacin; Gram-Negative Bacteria; | 1988 |
Aztreonam: therapy for infections in cancer patients.
Topics: Antineoplastic Agents; Aztreonam; Bacterial Infections; Humans; Kinetics; Neoplasms; Neutropenia | 1986 |