Page last updated: 2024-10-23

aztreonam and B cepacia Infection

aztreonam has been researched along with B cepacia Infection in 5 studies

Aztreonam: A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
aztreonam : A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Fischer, R1
Schwarz, C1
Weiser, R1
Mahenthiralingam, E1
Smerud, K1
Meland, N1
Flaten, H1
Rye, PD1
Barlow, G1
Morice, A1
Frost, F1
Shaw, M1
Nazareth, D1
Tullis, DE1
Burns, JL1
Retsch-Bogart, GZ1
Bresnik, M1
Henig, NR1
Lewis, SA1
Lipuma, JJ1
Balfour-Lynn, IM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Double-blind, Placebo-controlled Cross-over Study of Inhaled Alginate Oligosaccharide (OligoG) for 28 Days in Subjects With Cystic Fibrosis Using Aztreonam Due to Chronic Colonization With Burkholderia Spp.[NCT02453789]Phase 215 participants (Actual)Interventional2015-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aztreonam and B cepacia Infection

ArticleYear
Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis.
    The Cochrane database of systematic reviews, 2019, 06-13, Volume: 6

    Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Aztreonam; Burkholderia cepacia complex; B

2019

Trials

2 trials available for aztreonam and B cepacia Infection

ArticleYear
Evaluating the alginate oligosaccharide (OligoG) as a therapy for Burkholderia cepacia complex cystic fibrosis lung infection.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2022, Volume: 21, Issue:5

    Topics: Alginates; Aztreonam; Burkholderia cepacia complex; Burkholderia Infections; Cystic Fibrosis; Humans

2022
Inhaled aztreonam for chronic Burkholderia infection in cystic fibrosis: a placebo-controlled trial.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2014, Volume: 13, Issue:3

    Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Burkholderia Infect

2014

Other Studies

2 other studies available for aztreonam and B cepacia Infection

ArticleYear
Successful treatment of resistant Burkholderia multivorans infection in a patient with cystic fibrosis using ceftazidime/avibactam plus aztreonam.
    The Journal of antimicrobial chemotherapy, 2018, 08-01, Volume: 73, Issue:8

    Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; beta-Lactamase Inhibitors; Burkholderia; Bur

2018
At last, Burkholderia spp. is one of the inclusion criteria--a negative (but published) randomised controlled trial.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2014, Volume: 13, Issue:3

    Topics: Anti-Bacterial Agents; Aztreonam; Burkholderia Infections; Cystic Fibrosis; Female; Humans; Male

2014