aztreonam has been researched along with Allergy, Drug in 37 studies
Aztreonam: A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
aztreonam : A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The immunogenicity, allergenicity, and cross-reactivity of aztreonam were investigated in 21 patients with cystic fibrosis (CF) (aged 5 to 39 years) with well-documented histories of allergic systemic reactions (SRs) to penicillin and/or cephalosporin antipseudomonal beta-lactam antibiotics (BLAs)." | 9.07 | Sensitization to aztreonam and cross-reactivity with other beta-lactam antibiotics in high-risk patients with cystic fibrosis. ( Moss, RB, 1991) |
| "To report the successful desensitization of a highly allergic patient with cystic fibrosis (CF) to inhaled aztreonam lysine using the novel approach of intravenous desensitization followed by full-dose inhaled therapy without any adverse reactions." | 7.78 | Desensitization to inhaled aztreonam lysine in an allergic patient with cystic fibrosis using a novel approach. ( Abdulhamid, I; Ditouras, J; Guglani, L; Montejo, J, 2012) |
| "The immunogenicity, allergenicity, and cross-reactivity of aztreonam were investigated in 21 patients with cystic fibrosis (CF) (aged 5 to 39 years) with well-documented histories of allergic systemic reactions (SRs) to penicillin and/or cephalosporin antipseudomonal beta-lactam antibiotics (BLAs)." | 5.07 | Sensitization to aztreonam and cross-reactivity with other beta-lactam antibiotics in high-risk patients with cystic fibrosis. ( Moss, RB, 1991) |
| "We sought to evaluate the possibility of using cephalosporins and aztreonam in subjects with documented delayed hypersensitivity to penicillins who especially require them." | 3.83 | Cross-reactivity and tolerability of aztreonam and cephalosporins in subjects with a T cell-mediated hypersensitivity to penicillins. ( Caruso, C; Gaeta, F; Maggioletti, M; Quaratino, D; Romano, A; Valluzzi, RL, 2016) |
| "To report the successful desensitization of a highly allergic patient with cystic fibrosis (CF) to inhaled aztreonam lysine using the novel approach of intravenous desensitization followed by full-dose inhaled therapy without any adverse reactions." | 3.78 | Desensitization to inhaled aztreonam lysine in an allergic patient with cystic fibrosis using a novel approach. ( Abdulhamid, I; Ditouras, J; Guglani, L; Montejo, J, 2012) |
| "Patients with a beta-lactam allergy label (BLAL) were found to have decreased utilization of beta-lactams (p < ." | 1.72 | Effects of reported beta-lactam allergies on pneumonia outcomes in lung transplant recipients. ( Axelrod, P; Holaday, E; Mishkin, A; Motzer, AR, 2022) |
| "Aztreonam use was also associated with increased utilization of aminoglycosides (28." | 1.62 | Empiric aztreonam is associated with increased mortality compared to beta-lactams in septic shock. ( Anderson, WE; Hammer, J; Heffner, AC; Jaffa, RK; Medaris, LA; Pillinger, KE, 2021) |
| " Patients with negative allergy testing with aztreonam underwent an intramuscular test dosing and were observed for 3 h." | 1.37 | Tolerability of aztreonam in patients with cell-mediated allergy to β-lactams. ( Aruanno, A; Buonomo, A; Colagiovanni, A; De Pasquale, T; Lombardo, C; Nucera, E; Pascolini, L; Patriarca, G; Pecora, V; Rizzi, A; Sabato, V; Schiavino, D, 2011) |
| "Aztreonam also has been found to be well-tolerated by highly penicillin-allergic patients." | 1.28 | Immunogenicity and cross-allergenicity of aztreonam. ( Adkinson, NF, 1990) |
| "Despite treatment of the bronchospasm and readministration of the same dose of phenoxymethyl penicillin, wheezing recurred requiring stopping the desensitization procedure." | 1.28 | Successful use of aztreonam in a patient who failed oral penicillin desensitization. ( Finnerty, N; Loria, RC; Wedner, HJ, 1989) |
| "IgE or immediate hypersensitivity cross-reactivity between aztreonam (a monobactam) and penicillin was investigated, since this will be an important consideration when therapy is chosen." | 1.27 | Lack of cross-reactivity between aztreonam , a monobactam antibiotic, and penicillin in penicillin-allergic subjects. ( Adkinson, NF; Hassner, A; Saxon, A; Swabb, EA; Wheeler, B, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (21.62) | 18.7374 |
| 1990's | 10 (27.03) | 18.2507 |
| 2000's | 1 (2.70) | 29.6817 |
| 2010's | 12 (32.43) | 24.3611 |
| 2020's | 6 (16.22) | 2.80 |
| Authors | Studies |
|---|---|
| Motzer, AR | 1 |
| Holaday, E | 1 |
| Axelrod, P | 1 |
| Mishkin, A | 1 |
| Ramsey, A | 2 |
| Rozario, C | 1 |
| Stern, J | 1 |
| Otani, IM | 1 |
| Tang, M | 1 |
| Wang, L | 1 |
| Anstey, KM | 1 |
| Hilts-Horeczko, A | 1 |
| Li, F | 1 |
| Le, VP | 1 |
| Lee, M | 1 |
| Bystritsky, R | 1 |
| Mulliken, JS | 1 |
| Wattier, RL | 1 |
| Blumenthal, KG | 1 |
| Doernberg, SB | 1 |
| Peña-Mendizabal, E | 2 |
| Morais, S | 2 |
| Maquieira, Á | 2 |
| Jaffa, RK | 1 |
| Hammer, J | 1 |
| Medaris, LA | 1 |
| Anderson, WE | 1 |
| Heffner, AC | 1 |
| Pillinger, KE | 1 |
| Clark, KE | 1 |
| Briand, ME | 1 |
| Kapoor, O | 1 |
| Pirasteh, A | 1 |
| Phan, A | 1 |
| Allen, B | 1 |
| Epps, K | 1 |
| Alikhil, M | 1 |
| Kamataris, K | 1 |
| Tucker, C | 1 |
| Jenkins, RE | 1 |
| Yaseen, FS | 1 |
| Monshi, MM | 1 |
| Whitaker, P | 2 |
| Meng, X | 1 |
| Farrell, J | 1 |
| Hamlett, J | 1 |
| Sanderson, JP | 1 |
| El-Ghaiesh, S | 1 |
| Peckham, D | 2 |
| Pirmohamed, M | 1 |
| Park, BK | 1 |
| Naisbitt, DJ | 1 |
| McCullough, BJ | 1 |
| Wiggins, LE | 1 |
| Richards, A | 1 |
| Klinker, K | 1 |
| Hiemenz, JW | 1 |
| Wingard, JR | 1 |
| Gaeta, F | 2 |
| Valluzzi, RL | 2 |
| Alonzi, C | 1 |
| Maggioletti, M | 2 |
| Caruso, C | 2 |
| Romano, A | 2 |
| Swearingen, SM | 1 |
| White, C | 1 |
| Weidert, S | 1 |
| Hinds, M | 1 |
| Narro, JP | 1 |
| Guarascio, AJ | 1 |
| Staicu, ML | 1 |
| Brundige, ML | 1 |
| Brown, J | 1 |
| Yamshchikov, A | 1 |
| Peterson, DR | 1 |
| Baran, A | 1 |
| Laguio-Vila, M | 1 |
| Estep, PM | 1 |
| Ferreira, JA | 1 |
| Dupree, LH | 1 |
| Aldridge, PJ | 1 |
| Jankowski, CA | 1 |
| Quaratino, D | 1 |
| Buonomo, A | 1 |
| Nucera, E | 1 |
| De Pasquale, T | 1 |
| Pecora, V | 1 |
| Lombardo, C | 1 |
| Sabato, V | 1 |
| Colagiovanni, A | 1 |
| Rizzi, A | 1 |
| Aruanno, A | 1 |
| Pascolini, L | 1 |
| Patriarca, G | 1 |
| Schiavino, D | 1 |
| Etherington, C | 1 |
| Williams, K | 1 |
| Conway, S | 1 |
| Guglani, L | 1 |
| Abdulhamid, I | 1 |
| Ditouras, J | 1 |
| Montejo, J | 1 |
| De Maria, C | 1 |
| Lebel, D | 1 |
| Desroches, A | 1 |
| Gauvin, F | 1 |
| Saxon, A | 5 |
| Hassner, A | 1 |
| Swabb, EA | 2 |
| Wheeler, B | 1 |
| Adkinson, NF | 3 |
| Pérez Pimiento, A | 1 |
| Gómez Martínez, M | 1 |
| Mínguez Mena, A | 1 |
| Trampal González, A | 1 |
| de Paz Arranz, S | 1 |
| Rodríguez Mosquera, M | 2 |
| Shimizu, T | 1 |
| Souma, S | 1 |
| Nagakura, N | 1 |
| Masuzawa, T | 1 |
| Iwamoto, Y | 1 |
| Yanagihara, Y | 1 |
| Martin, JA | 1 |
| Igea, JM | 1 |
| Fraj, J | 1 |
| Lezaun, A | 1 |
| Parra, F | 1 |
| Losada, E | 1 |
| Soto Alvarez, J | 1 |
| Sacristán del Castillo, JA | 1 |
| Sampedro García, I | 1 |
| Alsar Ortiz, MJ | 1 |
| Iglesias Cadarso, A | 1 |
| Sáez Jiménez, SA | 1 |
| Vidal Pan, C | 1 |
| Moss, RB | 1 |
| Hantson, P | 1 |
| de Coninck, B | 1 |
| Horn, JL | 1 |
| Mahieu, P | 1 |
| Vega, JM | 1 |
| Blanca, M | 1 |
| García, JJ | 1 |
| Miranda, A | 1 |
| Carmona, MJ | 1 |
| García, A | 1 |
| Moya, MC | 1 |
| Sanchez, F | 1 |
| Terrados, S | 1 |
| Fekete, T | 1 |
| Marcelo, L | 1 |
| Kreter, B | 1 |
| Loria, RC | 1 |
| Finnerty, N | 1 |
| Wedner, HJ | 1 |
| Jensen, T | 1 |
| Koch, C | 1 |
| Pedersen, SS | 1 |
| Høiby, N | 1 |
| Lebel, MH | 1 |
| McCracken, GH | 1 |
| Beall, GN | 1 |
| Rohr, AS | 1 |
| Adelman, DC | 1 |
4 reviews available for aztreonam and Allergy, Drug
| Article | Year |
|---|---|
Direct challenges are the gold standard for most antibiotic allergy evaluations.
Topics: Adult; Anti-Bacterial Agents; Aztreonam; Cephalosporins; Child; Drug Hypersensitivity; Humans; Hyper | 2023 |
Aztreonam in the management of gram-negative infections in penicillin-allergic patients: a review.
Topics: Aztreonam; Bacterial Infections; Cephalosporins; Cross Reactions; Drug Hypersensitivity; Gram-Negati | 1989 |
Aztreonam: review of the clinical experience and potential uses in pediatrics.
Topics: Adolescent; Aztreonam; Bacterial Infections; Child; Child, Preschool; Cross Reactions; Cystic Fibros | 1988 |
Immediate hypersensitivity reactions to beta-lactam antibiotics.
Topics: Anti-Bacterial Agents; Aztreonam; Cephalosporins; Cross Reactions; Drug Hypersensitivity; Humans; Hy | 1987 |
1 trial available for aztreonam and Allergy, Drug
| Article | Year |
|---|---|
Sensitization to aztreonam and cross-reactivity with other beta-lactam antibiotics in high-risk patients with cystic fibrosis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibodies, Anti-Idiotypic; Azlocillin; Aztreonam; Ceftazi | 1991 |
32 other studies available for aztreonam and Allergy, Drug
| Article | Year |
|---|---|
Effects of reported beta-lactam allergies on pneumonia outcomes in lung transplant recipients.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Aztreonam; beta-Lactams; Carbapenems; Clostridium Infect | 2022 |
Impact of an Inpatient Allergy Guideline on β-Lactam and Alternative Antibiotic Use.
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactams; Cephalosporins; Drug Hypersensitivity; Humans; Hyper | 2023 |
Neo-antigens for the serological diagnosis of IgE-mediated drug allergic reactions to antibiotics cephalosporin, carbapenem and monobactam.
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactams; Carbapenems; Cefotaxime; Ceftriaxone; Cefuroxime; Ce | 2020 |
Boosting the sensitivity of in vitroβ-lactam allergy diagnostic tests.
Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Aztreonam; beta-Lactams; Carbona | 2020 |
Empiric aztreonam is associated with increased mortality compared to beta-lactams in septic shock.
Topics: Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; APACHE; Aztreonam; beta-Lactams; Ce | 2021 |
Impact of a Standardized Beta-Lactam Allergy Questionnaire on Aztreonam Use.
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactams; Documentation; Drug Hypersensitivity; Female; Humans | 2019 |
Initiative to reduce aztreonam use in patients with self-reported penicillin allergy: Effects on clinical outcomes and antibiotic prescribing patterns.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Aztreonam; Cephalosporins; Drug Hypersensitiv | 2018 |
β-Lactam antibiotics form distinct haptenic structures on albumin and activate drug-specific T-lymphocyte responses in multiallergic patients with cystic fibrosis.
Topics: Aztreonam; beta-Lactamase Inhibitors; beta-Lactams; Cystic Fibrosis; Drug Hypersensitivity; Haptens; | 2013 |
Aztreonam for febrile neutropenia in patients with beta-lactam allergy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Aztreonam; beta-Lactams; Chemothe | 2014 |
Tolerability of aztreonam and carbapenems in patients with IgE-mediated hypersensitivity to penicillins.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aztreonam; Carbapenems; Cross Reactions; Drug Hypersensi | 2015 |
A multidimensional antimicrobial stewardship intervention targeting aztreonam use in patients with a reported penicillin allergy.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Aztreonam; Drug Hypersensitivity; Female; Hospitals, | 2016 |
Implementation of a penicillin allergy screening tool to optimize aztreonam use.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Aztreonam; Drug Hypersensitivity; Drug Utilization R | 2016 |
Impact of an antimicrobial stewardship initiative to evaluate β-lactam allergy in patients ordered aztreonam.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; beta-Lactams; Drug Hypersensitivity; | 2016 |
Cross-reactivity and tolerability of aztreonam and cephalosporins in subjects with a T cell-mediated hypersensitivity to penicillins.
Topics: Adolescent; Adult; Aged; Aztreonam; Cephalosporins; Cross Reactions; Drug Hypersensitivity; Female; | 2016 |
Tolerability of aztreonam in patients with cell-mediated allergy to β-lactams.
Topics: Adolescent; Adult; Aged; Angioedema; Anti-Bacterial Agents; Aztreonam; beta-Lactams; Cross Reactions | 2011 |
The use of nebulised aztreonam lysine (AZLI) in aztreonam hypersensitive patients.
Topics: Adult; Anti-Bacterial Agents; Aztreonam; Cystic Fibrosis; Drug Hypersensitivity; Humans; Nebulizers | 2012 |
Desensitization to inhaled aztreonam lysine in an allergic patient with cystic fibrosis using a novel approach.
Topics: Adult; Anti-Bacterial Agents; Aztreonam; Cystic Fibrosis; Desensitization, Immunologic; Drug Hyperse | 2012 |
Simple intravenous antimicrobial desensitization method for pediatric patients.
Topics: Adolescent; Anti-Bacterial Agents; Aztreonam; Ceftazidime; Child; Desensitization, Immunologic; Drug | 2002 |
Lack of cross-reactivity between aztreonam , a monobactam antibiotic, and penicillin in penicillin-allergic subjects.
Topics: Adult; Anti-Bacterial Agents; Aztreonam; Cross Reactions; Drug Hypersensitivity; Female; Humans; Hyp | 1984 |
Aztreonam and ceftazidime: evidence of in vivo cross allergenicity.
Topics: Aztreonam; Ceftazidime; Cephalosporins; Cross Reactions; Drug Hypersensitivity; Humans; Male; Middle | 1998 |
Epitope analysis of aztreonam by antiaztreonam monoclonal antibodies and possible consequences in beta-lactams hypersensitivity.
Topics: Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Aztreonam; Cross Reactions; Drug Hypersensit | 1992 |
Allergy to amoxicillin in patients who tolerated benzylpenicillin, aztreonam, and ceftazidime.
Topics: Adolescent; Adult; Amoxicillin; Aztreonam; Ceftazidime; Drug Hypersensitivity; Drug Tolerance; Femal | 1992 |
Immediate hypersensitivity to aztreonam.
Topics: Aged; Aztreonam; Cystitis; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Immediate | 1990 |
Aztreonam-induced anaphylaxis.
Topics: Anaphylaxis; Aztreonam; Drug Hypersensitivity; Humans; Skin Tests | 1990 |
Immediate hypersensitivity to aztreonam and imipenem.
Topics: Aztreonam; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; Imipenem; Male; Middle Aged | 1991 |
Tolerance to aztreonam in patients allergic to beta-lactam antibiotics.
Topics: Anti-Bacterial Agents; Aztreonam; Cross Reactions; Drug Hypersensitivity; Female; Humans; Immunoglob | 1991 |
Immunogenicity and cross-allergenicity of aztreonam.
Topics: Aztreonam; Cephalosporins; Cross Reactions; Drug Hypersensitivity; Humans; Penicillins | 1990 |
Aztreonam adverse reactions.
Topics: Aztreonam; Drug Hypersensitivity; Female; Humans; Male; Middle Aged | 1990 |
Successful use of aztreonam in a patient who failed oral penicillin desensitization.
Topics: Aged; Aztreonam; Bronchial Spasm; Desensitization, Immunologic; Drug Hypersensitivity; Female; Human | 1989 |
Investigation into the immunologic cross-reactivity of aztreonam with other beta-lactam antibiotics.
Topics: Adult; Aged; Anti-Bacterial Agents; Antibody Affinity; Antibody Formation; Aztreonam; Benzeneacetami | 1985 |
Aztreonam for cystic fibrosis patients who are hypersensitive to other beta-lactams.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Child; Cystic Fibrosis; Drug Hypersensitivity; | 1987 |
Antibiotic choices for the penicillin-allergic patient.
Topics: Animals; Anti-Bacterial Agents; Aztreonam; Bacterial Infections; Cephalosporins; Cross Reactions; Dr | 1988 |