aztreonam has been researched along with Acute Disease in 14 studies
Aztreonam: A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
aztreonam : A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We performed a comparative study between the monobactam antibiotic aztreonam and the aminoglycoside tobramycin in patients diagnosed as having acute pyelonephritis." | 9.06 | [Aztreonam versus tobramycin in acute pyelonephritis. A comparative study]. ( David Vera, C; Gallego, J; Gobernado, M; Jiménez Cruz, JF; Llopis, B; Ruiz, JL; Server, G; Vidal, J, 1989) |
| "The effects of aztreonam (AZT) on the morphology of Escherichia coli in the urine of 5 patients with acute simple cystitis were studied by differential interference contrast microscopy." | 7.67 | Morphological studies of Escherichia coli in the urine of patients with acute simple cystitis treated with aztreonam. ( Inuzuka, K; Iwase, Y; Sakagami, H; Takeuchi, K; Tsugaya, M; Washida, H, 1986) |
| "We performed a comparative study between the monobactam antibiotic aztreonam and the aminoglycoside tobramycin in patients diagnosed as having acute pyelonephritis." | 5.06 | [Aztreonam versus tobramycin in acute pyelonephritis. A comparative study]. ( David Vera, C; Gallego, J; Gobernado, M; Jiménez Cruz, JF; Llopis, B; Ruiz, JL; Server, G; Vidal, J, 1989) |
| " Thus, both the adverse prognostic effect of leukemia as an underlying disease and the poorer results obtained using aztreonam-containing regimens were evident only with certain outcome definitions." | 5.06 | The effect of different measures of outcome on the results of studies of empiric antibiotic therapy in febrile neutropenic patients. ( Elliott, CR; Pater, JL, 1988) |
| "The effects of aztreonam (AZT) on the morphology of Escherichia coli in the urine of 5 patients with acute simple cystitis were studied by differential interference contrast microscopy." | 3.67 | Morphological studies of Escherichia coli in the urine of patients with acute simple cystitis treated with aztreonam. ( Inuzuka, K; Iwase, Y; Sakagami, H; Takeuchi, K; Tsugaya, M; Washida, H, 1986) |
| "Nineteen patients with hematological malignancies (5 malignant lymphomas, 9 acute leukemia and 5 other hematological diseases) were treated with aztreonam alone or in combination for infection." | 3.67 | Treatment of infections during hematologic malignancies with aztreonam, a new antibiotic. ( Invernizzi, R; Mazzone, A; Nastasi, G; Ricevuti, G; Rizzo, SC, 1986) |
| "Aztreonam (AZT) was given intravenously to 20 children with the following acute bacterial infections: 13 cases of bronchopneumonia, 5 cases of urinary tract infection, 1 case of cervical lymphadenitis with acute tonsillitis and 1 case of acute enteritis." | 3.67 | [Clinical experience with aztreonam in the pediatric field]. ( Aihara, R; Kobashi, H; Nishioka, A; Okamoto, T; Oohara, K, 1985) |
| " Frequency of treatment-emergent adverse events between the groups was similar." | 2.87 | A Comparison of the Efficacy and Safety of Intravenous Followed by Oral Delafloxacin With Vancomycin Plus Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections: A Phase 3, Multinational, Double-Blind, Randomized Study. ( Cammarata, S; Cruz-Saldariagga, M; Lawrence, L; Liang, S; McManus, A; O'Riordan, W; Poromanski, I; Quintas, M; Teras, J, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| De Almeida Torres, N | 1 |
| Morales Junior, R | 1 |
| Bueno Lopes, LF | 1 |
| Zeigler, R | 1 |
| Everson Uip, D | 1 |
| O'Riordan, W | 1 |
| McManus, A | 1 |
| Teras, J | 1 |
| Poromanski, I | 1 |
| Cruz-Saldariagga, M | 1 |
| Quintas, M | 1 |
| Lawrence, L | 1 |
| Liang, S | 1 |
| Cammarata, S | 1 |
| Huang, X | 1 |
| Beresford, E | 1 |
| Lodise, T | 1 |
| Friedland, HD | 2 |
| O'Neal, T | 1 |
| Biek, D | 1 |
| Eckburg, PB | 1 |
| Rank, DR | 1 |
| Llorens, L | 1 |
| Smith, A | 1 |
| Witherell, GW | 1 |
| Laudano, JB | 1 |
| Thye, D | 1 |
| Mazzariol, A | 1 |
| Zuliani, J | 1 |
| Fontana, R | 1 |
| Cornaglia, G | 1 |
| Dodson, MG | 1 |
| Domínguez Herrera, JM | 1 |
| Jiménez Mejías, ME | 1 |
| Infante Cossio, P | 1 |
| Hernández Guisado, JM | 1 |
| Toyama, K | 1 |
| Yaguchi, M | 1 |
| Mizoguchi, H | 1 |
| Masuda, M | 1 |
| Urabe, A | 1 |
| Ikeda, Y | 1 |
| Aoki, I | 1 |
| Shinbo, T | 1 |
| Togawa, A | 1 |
| Hirashima, K | 1 |
| Miura, Y | 1 |
| Hirose, S | 1 |
| Tsuruoka, N | 1 |
| Omine, M | 1 |
| Kamakura, M | 1 |
| Saito, T | 1 |
| Arimori, S | 1 |
| Aoki, N | 1 |
| Kuraishi, Y | 1 |
| Hirai, H | 1 |
| Asano, S | 1 |
| Mori, M | 1 |
| Shirai, T | 1 |
| Muto, Y | 1 |
| Takaku, F | 1 |
| Becopoulos, T | 1 |
| Georgoulias, D | 1 |
| Constantinides, C | 1 |
| Stathakis, H | 1 |
| Kosmidis, J | 1 |
| Gallego, J | 1 |
| Jiménez Cruz, JF | 1 |
| Gobernado, M | 1 |
| Llopis, B | 1 |
| Vidal, J | 1 |
| Server, G | 1 |
| Ruiz, JL | 1 |
| David Vera, C | 1 |
| Elliott, CR | 1 |
| Pater, JL | 1 |
| Tsugaya, M | 1 |
| Washida, H | 1 |
| Sakagami, H | 1 |
| Iwase, Y | 1 |
| Inuzuka, K | 1 |
| Takeuchi, K | 1 |
| Rizzo, SC | 1 |
| Ricevuti, G | 1 |
| Invernizzi, R | 1 |
| Mazzone, A | 1 |
| Nastasi, G | 1 |
| Kobashi, H | 1 |
| Aihara, R | 1 |
| Nishioka, A | 1 |
| Oohara, K | 1 |
| Okamoto, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 3, Multicenter, Randomized, Double-blind, Active Controlled Study to Evaluate the Efficacy + Safety of IV + Oral Delafloxacin Compared With Vancomycin + Aztreonam in Patients With Acute Bacterial Skin and Skin Structure Infections (ABSSSI)[NCT01984684] | Phase 3 | 850 participants (Actual) | Interventional | 2014-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for aztreonam and Acute Disease
| Article | Year |
|---|---|
Antibiotic regimens for treating acute pelvic inflammatory disease. An evaluation.
Topics: Acute Disease; Anti-Bacterial Agents; Aztreonam; Cefotetan; Cefoxitin; Chlamydia Infections; Chlamyd | 1994 |
5 trials available for aztreonam and Acute Disease
| Article | Year |
|---|---|
A Comparison of the Efficacy and Safety of Intravenous Followed by Oral Delafloxacin With Vancomycin Plus Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections: A Phase 3, Multinational, Double-Blind, Randomized Study.
Topics: Acute Disease; Administration, Intravenous; Administration, Oral; Adult; Aztreonam; Community-Acquir | 2018 |
CANVAS 1 and 2: analysis of clinical response at day 3 in two phase 3 trials of ceftaroline fosamil versus vancomycin plus aztreonam in treatment of acute bacterial skin and skin structure infections.
Topics: Acute Disease; Aged; Aged, 80 and over; Anti-Bacterial Agents; Aztreonam; Biomarkers; Ceftaroline; C | 2012 |
Effect of recombinant human granulocyte colony-stimulating factor on combination therapy with aztreonam and clindamycin for infections in neutropenic patients with hematologic diseases.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aztreonam; Clindamycin; Drug Therapy, Com | 1996 |
[Aztreonam versus tobramycin in acute pyelonephritis. A comparative study].
Topics: Acute Disease; Adult; Aged; Aztreonam; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Ma | 1989 |
The effect of different measures of outcome on the results of studies of empiric antibiotic therapy in febrile neutropenic patients.
Topics: Acute Disease; Agranulocytosis; Anti-Bacterial Agents; Aztreonam; Clinical Trials as Topic; Cloxacil | 1988 |
8 other studies available for aztreonam and Acute Disease
| Article | Year |
|---|---|
Synergistic combination of aztreonam and ceftazidime/avibactam against resistant Stenotrophomonas maltophilia on pancreatitis.
Topics: Acute Disease; Aged; Anti-Bacterial Agents; Aztreonam; Ceftazidime; Diabetes Mellitus, Type 2; Drug | 2023 |
Ceftaroline fosamil use in hospitalized patients with acute bacterial skin and skin structure infections: Budget impact analysis from a hospital perspective.
Topics: Acute Disease; Adult; Anti-Bacterial Agents; Aztreonam; Ceftaroline; Cephalosporins; Costs and Cost | 2013 |
Isolation from blood culture of a Leclercia adecarboxylata strain producing an SHV-12 extended-spectrum beta-lactamase.
Topics: Acute Disease; Anti-Bacterial Agents; Aztreonam; Bacteremia; beta-Lactam Resistance; beta-Lactamases | 2003 |
[Acute bacterial parotitis caused by Serratia marcescens].
Topics: Acute Disease; Aztreonam; Cefotaxime; Cephalosporins; Child; Diagnosis, Differential; Female; Humans | 1996 |
Acute prostatitis: which antibiotic to use first.
Topics: Acute Disease; Anti-Bacterial Agents; Aztreonam; Cefuroxime; Humans; Male; Netilmicin; Prostate; Pro | 1990 |
Morphological studies of Escherichia coli in the urine of patients with acute simple cystitis treated with aztreonam.
Topics: Acute Disease; Aztreonam; Cystitis; Escherichia coli; Female; Humans; Urine | 1986 |
Treatment of infections during hematologic malignancies with aztreonam, a new antibiotic.
Topics: Acute Disease; Aztreonam; Bacterial Infections; Humans; Leukemia; Lymphoma | 1986 |
[Clinical experience with aztreonam in the pediatric field].
Topics: Acute Disease; Age Factors; Aztreonam; Bacteria; Bronchopneumonia; Child; Child, Preschool; Drug Eva | 1985 |