azoxymethane has been researched along with Precancerous Conditions in 295 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (3.05) | 18.7374 |
| 1990's | 88 (29.83) | 18.2507 |
| 2000's | 157 (53.22) | 29.6817 |
| 2010's | 35 (11.86) | 24.3611 |
| 2020's | 6 (2.03) | 2.80 |
| Authors | Studies |
|---|---|
| Allaman, MM; Asim, M; Barry, DP; Coburn, LA; Delgado, AG; Finley, JL; Gobert, AP; Latour, YL; Luis, PB; McNamara, KM; Piazuelo, MB; Schneider, C; Sierra, JC; Singh, K; Smith, TM; Washington, MK; Wilson, KT; Zhao, S | 1 |
| Bailey, MT; Chatelaine, HA; Hatzakis, E; Kopec, RE; Mathé, EA; McElroy, J; Olivo-Marston, S; Ramazani, CA; Spencer, K | 1 |
| Allred, CD; Allred, KF; Callaway, ES; Chapkin, RS; Davidson, LA; DeLuca, JAA; Garcia-Villatoro, EL; Hensel, ME; Ivanov, I; Jayaraman, A; Menon, R; Safe, SH | 1 |
| Chen, D; Huang, Z; Liu, Y; Ma, H; Ouyang, G; Wang, J; Wu, T; Zhao, X | 1 |
| Ibuka, T; Kato, J; Kubota, M; Mizutani, T; Sakai, H; Shimizu, M; Shirakami, Y | 1 |
| Bodiga, VL; Jeevigunta, NLL; Velagapudi, K | 1 |
| Bi, W; Cao, L; He, C; Li, P; Liu, H; Peng, B; Shen, J; Xiao, P; Zhang, LH; Zhang, P | 1 |
| Lin, JA; Wu, CH; Yen, GC | 1 |
| Braga, VNL; Cavalcanti, BC; Dornelas, CA; Jamacaru, FVF; Juanes, CC; Lemos, TLG; Peres Júnior, HS; Sousa, JR | 1 |
| Baba, A; Kochi, T; Kubota, M; Moriwaki, H; Ohno, T; Shimizu, M; Shirakami, Y; Sumi, T; Tanaka, T; Tsurumi, H | 1 |
| Brigelius-Flohé, R; Chu, FF; Esworthy, RS; Florian, S; Kipp, AP; Müller, MF; Osterhoff, M; Pommer, S | 1 |
| Hu, Y; LE Leu, RK; Martin, JE; Young, GP | 1 |
| Esa, F; Jamal, AR; Mohd Yusof, YA; Ngah, WZ | 1 |
| Cichello, SA; Duan, JL; He, XQ; Zhou, J | 1 |
| Han, W; Li, W; Wang, H; Zhao, X | 1 |
| Ramana, KV; Saxena, A; Shoeb, M; Srivastava, SK; Tammali, R | 1 |
| Kochi, T; Kubota, M; Moriwaki, H; Shimizu, M; Shirakami, Y; Sumi, T; Tanaka, T | 1 |
| Campanholo, VM; Forones, NM; Neto, RA; Paiotti, AP; Ribeiro, DA; Silva, RM; Silva, TD | 1 |
| Chaiyasut, C; Riengrojpitak, S; Suwannalert, P; Tammasakchai, A | 1 |
| Abdulla, MA; Abdullah, NA; Al-Henhena, NA; Alshawsh, MA; El-Seedi, HR; Khalifa, SA; Shwter, AN | 1 |
| Chaiyasut, C; Reungpatthanaphong, S; Sirilun, S; Suwannalert, P | 1 |
| Ahmad, J; El-Shemi, AG; Idris, S; Kensara, OA; Mohamed, AM; Refaat, B | 1 |
| Liu, R; Xu, G | 1 |
| Endo, H; Fujisawa, T; Inamori, M; Kadowaki, T; Kubota, N; Nakagama, H; Nakajima, A; Nakajima, N; Saito, S; Sugiyama, M; Takahashi, H; Tomimoto, A; Wada, K; Watanabe, M; Yamauchi, T | 1 |
| Jiang, B; Lin, C; Lu, Q; Shan, T | 1 |
| Kim, M; Kohno, H; Miyamoto, S; Sugie, S; Tanaka, T; Yasui, Y | 1 |
| Callaway, ES; Chapkin, RS; Davidson, LA; Finnell, RH; George, NI; Kamen, BA; Lupton, JR; Wang, N | 1 |
| Ishigamori-Suzuki, R; Oyama, T; Tanaka, T; Yasui, Y | 1 |
| Petrash, JM; Ramana, KV; Reddy, AB; Srivastava, SK; Tammali, R | 1 |
| Raju, J | 1 |
| Alink, GM; Bosch, D; Mooibroek, H; Rietjens, IM; Sijtsma, L; Spenkelink, B; van Beelen, VA | 1 |
| Archer, MC; Ealey, KN | 1 |
| Adachi, S; Hata, K; Hirose, Y; Moriwaki, H; Sakai, H; Shimizu, M; Shirakami, Y; Tanaka, T; Tsurumi, H | 1 |
| Agarwal, R; Singh, RP; Tyagi, A; Velmurugan, B | 1 |
| Albert, PS; Barrett, KG; Bennink, MR; Bobe, G; Colburn, NH; Lanza, E; Mentor-Marcel, RA; Young, MR | 1 |
| Archer, MC; Lau, DS | 1 |
| Arihara, K; Asano, T; Ishikawa, S; Itoh, M; Nozawa, Y; Takenoshita, S | 1 |
| Hata, K; Hirose, Y; Iwasa, J; Moriwaki, H; Shimizu, M; Shirakami, Y; Shiraki, M; Tanaka, T; Tsurumi, H; Yasuda, Y | 1 |
| Begleiter, A; Bird, RP; Lefas, GM; Maksymiuk, AW; Sivananthan, K | 1 |
| Caderni, G; Dolara, P; Femia, AP; Luceri, C; Salvadori, M | 1 |
| Bifulco, M; Borrelli, F; Gazzerro, P; Grimaldi, C; Izzo, AA; Laezza, C; Malfitano, AM; Pisanti, S; Proto, MC; Santoro, A | 1 |
| Fujimoto, K; Fujise, T; Iwakiri, R; Kakimoto, T; Kuroki, T; Miao, L; Noda, T; Sakata, Y; Shiraishi, R; Tsunada, S | 1 |
| Boring, D; Grubbs, CJ; Juliana, MM; Kopelovich, L; Lubet, RA; Patlolla, J; Rao, CV; Steele, VE; Zhang, Y | 1 |
| Miyamoto, S; Murakami, A; Ohigashi, H; Tanaka, T; Yasui, Y | 1 |
| Fujimoto, K; Fujise, T; Iwakiri, R; Kakimoto, T; Kuroki, T; Nakashima, Y; Sakata, Y; Shiraishi, R; Takashima, T; Tsunada, S; Yanagita, T | 1 |
| Birt, DF; Brummer, EC; Kineman, BD; Paiva, NL | 1 |
| Bruno, RS; Davis, SR; Liang, HY; Park, HJ; Rosenberg, DW | 1 |
| Hata, K; Hirose, Y; Kubota, M; Moriwaki, H; Sakai, H; Shimizu, M; Shirakami, Y; Tanaka, T; Tsurumi, H; Yasuda, Y | 1 |
| Allam, O; Corpet, DE; Gueraud, F; Naud, N; Pierre, FH; Santarelli, RL; Tache, S | 1 |
| Bean, E; Currey, N; Dahlstrom, JE; Daniel, JJ; Gupta, R; Kohonen-Corish, MR; Mladenova, D; Musgrove, EA; Pickford, R | 1 |
| Cerar, A; Perše, M | 1 |
| Kochi, T; Kubota, M; Moriwaki, H; Ohno, T; Sakai, H; Shimizu, M; Tanaka, T; Tsurumi, H; Yasuda, Y | 1 |
| Birt, DF; Hasjim, J; Hendrich, S; Jane, JL; Li, L; Zhao, Y | 1 |
| Chaudhary, A; Huang, Y; Prabhu, S; Sutaria, D; Wang, J | 1 |
| Agis-Torres, A; Bravo, L; Gómez-Juaristi, M; Goya, L; López-Oliva, E; Martín, MÁ; Mateos, R; Ramos, S; Rodríguez-Ramiro, I | 1 |
| Li, Q; Patlolla, JM; Rao, CV; Steele, VE; Zhang, Y | 1 |
| Baba, A; Kubota, M; Moriwaki, H; Ohno, T; Sakai, H; Shimizu, M; Tanaka, T; Terakura, D; Tsurumi, H; Yasuda, Y | 1 |
| Hara, A; Hata, K; Hirose, Y; Kubota, M; Kuno, T; Moriwaki, H; Shimizu, M; Tanaka, T | 1 |
| Hara, T; Hoshi, M; Ito, H; Moriwaki, H; Nagano, J; Ninomiya, S; Ogawa, K; Saito, K; Sakai, H; Seishima, M; Shimizu, M; Tanaka, T; Tsurumi, H | 1 |
| Bian, Z; Gou, X; Jia, W; Kou, F; Liao, W; Qiu, Y; Wang, X; Wei, H; Wu, J; Wu, T; Xie, G; Zhang, X; Zhang, Y; Zhou, M | 1 |
| Chen, H; Li, Q; Zhang, Y; Zhou, D | 1 |
| Clarke, M; Das, S; Huels, D; Jamieson, T; Jung, A; Neumann, J; Nibbs, RJ; Olson, MF; Samuel, MS; Sansom, OJ; Steele, CW | 1 |
| Cobb, S; Given, R; Singh, P; Tarasova, N; Tessarollo, L; Varro, A; Velasco, M; Wood, T | 1 |
| Hasegawa, J; Hosoda, A; Kawasaki, H; Kishimoto, Y; Morisawa, T; Shiota, G | 1 |
| Meyer, O; Mølck, AM; Poulsen, M | 1 |
| Chawan, CB; Rao, DR; Shackelford, L; Verghese, M | 1 |
| Chawan, CB; Rao, DR; Shackelford, L; Verghese, M; Williams, LL | 1 |
| Matsuhashi, N; Nagase, H; Nakagama, H; Nakajima, A; Ochiai, M; Omura, M; Osawa, E; Sekihara, H; Ueno, N; Wada, K; Yoshida, S | 1 |
| Bensasson, RV; Boone, CW; Dauzonne, D; Rao, CV; Steele, VE | 1 |
| Hasegawa, J; Idobe-Fujii, Y; Kishimoto, Y; Marumoto, A; Miura, N; Morisawa, T; Murawaki, Y; Ohishi, T; Sano, A; Shiota, G; Yashima, K | 1 |
| Girnun, G; Guda, K; Lillo, NA; Nambiar, PR; Rosenberg, DW; Whiteley, HE | 1 |
| Breinholt, V; Meyer, O; Mølck, AM; Poulsen, M; Thorup, I | 1 |
| Newmark, HL; Rao, CV; Reddy, BS | 2 |
| Kosmeder, JW; Mehta, RG; Murillo, G; Pezzuto, JM | 1 |
| Bruce, WR; Chia, MC; Giacca, A; Goh, T; Gupta, N; Koohestani, N; McKeown-Eyssen, G; Mehrotra, S; Naigamwalla, D; Tran, TT | 1 |
| Exon, JH; South, EH | 1 |
| Bruce, WR | 1 |
| Corpet, DE; Pierre, F | 1 |
| Caderni, G; Dolara, P; Favuzza, A; Femia, AP; Giannini, A; Luceri, C; Salvadori, M | 1 |
| Das, S; Ghosh, S; Sengupta, A | 3 |
| Belobrajdic, DP; McIntosh, GH; Owens, JA | 1 |
| Barbier, JR; Bird, RP; MacLean, S; Morley, P; Ross, V; Whitfield, J; Willick, GE | 1 |
| Bird, RP; Raju, J | 1 |
| Caderni, G; Dolara, P; Femia, AP | 1 |
| Kataoka, K; Kuwahara, T; Nakanishi, S; Ohnishi, Y | 1 |
| Hata, K; Hirose, Y; Kuno, T; Mori, H; Reddy, BS; Sakata, K; Tanaka, T; Yamada, Y; Yoshida, K | 1 |
| Exon, J; Nichenametla, S; South, E | 1 |
| Aparicio, T; Bado, A; Goiot, H; Guilmeau, S; Laigneau, JP; Lehy, T; Sobhani, I; Tsocas, A | 1 |
| Ceci, J; Cobb, S; Singh, P; Varro, A; Velasco, M; Wood, T | 1 |
| Aniya, Y; Ichiba, T; Inamine, M; Mori, H; Morioka, T; Nabandith, V; Nakayama, T; Suzui, M; Yoshimi, N | 1 |
| Kohno, H; Sasaki, K; Sugie, S; Suzuki, R; Tanaka, T; Wada, K; Yoshimura, T | 1 |
| Lai, MD; Sheng, HQ | 1 |
| Patlolla, JM; Raju, J; Rao, CV; Swamy, MV | 1 |
| Carroll, RE; Heap, D; Poole, AJ; Tyner, AL | 1 |
| Kohno, H; Sugie, S; Suzuki, R; Tanaka, T | 1 |
| Belinsky, GS; Blumberg, JB; Guda, K; Huang, X; Ilsley, JN; Milbury, PE; Roberts, LJ; Rosenberg, DW; Stevens, RG; Zhang, Q | 1 |
| Cooma, I; Patlolla, JM; Pittman, B; Raju, J; Rao, CV; Reddy, BS; Steele, VE; Swamy, MV | 1 |
| Kral, JG; Stein, DE | 1 |
| Bozinov, D; Callaway, ES; Chapkin, RS; Davidson, LA; Finnell, RH; James, J; Kappen, C; Lupton, JR; Ma, DW; Piedrahita, JA; Salbaum, JM; Spiegelstein, O; Weeks, BR | 1 |
| Brandt, K; Christensen, LP; Kobaek-Larsen, M; Ritskes-Hoitinga, J; Vach, W | 1 |
| Backman, V; Goldberg, MJ; Kim, YL; Koetsier, JL; Kunte, DP; Liu, Y; Roy, HK; Turzhitsky, V; Wali, RK | 1 |
| Belalcazar, LM; Cowey, SL; Deng, X; Given, R; Quast, M; Singh, P; Wei, J | 1 |
| Bruce, WR; Hughes, R; Karlsson, PC; Rafter, JJ | 1 |
| Kondo, K; Nakao, W; Nozawa, H; Zhao, F | 1 |
| Aviello, G; Borrelli, F; Capasso, F; Capasso, R; Di Carlo, G; Izzo, AA; Mascolo, N | 1 |
| Hara, A; Hata, K; Hirose, Y; Kohno, H; Kuno, T; Mori, H; Qiang, SH; Suzuki, R; Tanaka, T | 1 |
| Alexander, J; Knutsen, H; Løberg, EM; Paulsen, JE; Ølstørn, HB | 1 |
| Kamanaka, Y; Maruyama, T; Mutoh, M; Naka, M; Sato, H; Shoji, Y; Sugimura, T; Takahashi, M; Wakabayashi, K | 1 |
| Baba, M; Das, SK; Kanazawa, K; Matsuura, Y; Shimizu, K | 1 |
| Baldwin, GS; Giraud, AS; Houli, N; Loh, SW; Shulkes, A | 1 |
| Gallaher, DD; Yang, Y | 1 |
| Asano, N; Hara, A; Hata, K; Hirose, Y; Kuno, T; Mori, H; Osawa, T; Sheng, H; Yamada, Y; Zheng, Q | 1 |
| Kohno, H; Miyamoto, S; Murakami, A; Ohigashi, H; Sugie, S; Suzuki, R; Tanaka, T | 1 |
| Corpet, DE; Parnaud, G; Taché, S; Van Beek, E | 1 |
| Boateng, J; Chawan, CB; Khatiwada, J; Shackelford, L; Verghese, M; Walker, LT; Williams, DS | 1 |
| Komninou, D; Leutzinger, Y; Reddy, BS; Richie, JP | 1 |
| Au, A; Birt, D; Koehler, K; Li, B; Roy, H; Wang, W | 1 |
| Hosokawa, M; Kohno, H; Miyamoto, S; Miyashita, K; Suzuki, R; Tanaka, T; Yasui, Y | 1 |
| Dragsted, LO; Jacobsen, H; Lindecrona, RH; Meyer, O; Poulsen, M; Ravn-Haren, G | 1 |
| Boateng, J; Chawan, CB; Shackelford, L; Verghese, M; Walker, LT; Williams, D | 1 |
| Alink, GM; Bruijntjes, JP; de Boer, VC; Dihal, AA; Rietjens, IM; Stierum, RH; Tilburgs, C; van der Woude, H; Woutersen, RA | 1 |
| Hata, K; Hirose, Y; Kohno, H; Miyamoto, S; Sugawara, K; Sugie, S; Sumida, T; Suzuki, R; Tanaka, T; Yasui, Y | 1 |
| Flynn, C; Ilsley, JN; Montrose, DC; Nakanishi, M; Rosenberg, DW; Swank, DL | 1 |
| Daly, KT; Francke-Carroll, S; Magnuson, BA; Malik, M; Tracy, AC; Wang, T | 1 |
| Huang, MT; Newmark, HL; Reddy, BS | 1 |
| Fujimoto, K; Fujise, T; Iwakiri, R; Kakimoto, T; Ootani, A; Sakata, Y; Shiraishi, R; Tsunada, S; Wu, B | 1 |
| Chan, HY; Chen, MH; Lin, SY; Shen, FH; Wang, YJ; Yu, CK | 1 |
| Amaral, EG; Fagundes, DJ; Inouye, CM; Marks, G | 1 |
| Asiamah, D; Boateng, J; Chawan, CB; DeBruce, M; Grant, L; Guyton, M; Henderson, F; Johnson, A; Jones, J; Khatiwada, J; Ogutu, S; Shackelford, L; Verghese, M; Walker, LT; Washington, S; Williams, DS | 1 |
| Hirschelman, WH; Ito, A; Kinghorn, AD; Mehta, RG; Moriarty, RM; Murillo, G; Pezzuto, JM | 1 |
| Hayashi, K; Kohno, H; Miyamoto, S; Shin-Ichiroh, Y; Sugie, S; Suzuki, R; Takashima, S; Tanaka, T | 1 |
| Alain, T; Beck, PL; Endersby, R; Forsyth, PA; Johnston, RN; Lee, PW; Muruve, DA; Urbanski, SJ; Wong, JF | 1 |
| Carroll, RE; Fernandez, PA; Hagos, GK; Kouznetsova, T; Li, Q; Swanson, SM; Thatcher, GR; Toader, V | 1 |
| Choi, CI; Guruswamy, S; Rao, CV; Steele, VE; Swamy, MV | 1 |
| Crary, K; Dong, M; Guda, K; Jung, Y; Marino, JN; Rosenberg, DW | 1 |
| Aviello, G; Borrelli, F; Capasso, F; Capasso, R; Di Marzo, V; Izzo, AA; Lutz, B; Marsicano, G; Nigam, S; Orlando, P; Petrosino, S | 1 |
| Hao, X; Jiang, H; Ju, J; Reddy, BS; Simi, B; Xiao, H; Yang, CS | 1 |
| Beppu, F; Hosokawa, M; Kohno, H; Miyamoto, S; Miyashita, K; Suzuki, R; Tanaka, T; Yasui, Y | 1 |
| Christudoss, P; Fleming, JJ; Mathew, G; Pulimood, AB; Selvakumar, R | 1 |
| Brooke, DA; Coletta, PL; Cuthbert, RJ; Hull, MA; Ko, CW; Markham, AF; Orsi, NM; Perry, SL | 1 |
| Calcagno, SR; Colon, M; Fields, AP; Kreinest, PA; Li, S; Murray, NR; Thompson, EA | 1 |
| Esumi, H; Fujii, S; Fujioka, R; Kuga, W; Ochiai, A; Ochiya, T; Ogura, T; Saito, M; Tsuchihara, K | 1 |
| Indranie, C; Jagan, P; Janakiram, NB; Malisetty, SV; Rao, CV; Steele, VE | 1 |
| Aluri, L; Bissonnette, M; Cerda, S; Chumsangsri, A; Cohen, EE; Delgado, J; Dougherty, U; Fichera, A; Hart, J; Jagadeeswaran, S; Joseph, L; Little, N; Mustafi, R; Sehdev, A; Tretiakova, M; Yuan, W | 1 |
| Cooke, T; Goeting, N; Inman, C; Kirkham, N; Stainthorp, DH; Taylor, I | 1 |
| Shamsuddin, AM | 1 |
| Shamsuddin, AK; Trump, BF | 1 |
| Bird, RP | 2 |
| Biggeri, A; Caderni, G; Dolara, P; Giannini, A; Lancioni, L; Luceri, C | 1 |
| Kawamori, T; Mori, H; Okamoto, K; Suzui, M; Tamai, Y; Tanaka, T; Torihara, M; Yamahara, J | 1 |
| Kulkarni, N; Reddy, BS | 1 |
| Chen, CD; Harris, C; Velasco, M; Wargovich, MJ; Yang, E | 1 |
| Alabaster, O; Frost, A; Shivapurkar, N; Tang, Z | 1 |
| Hara, A; Kawamori, T; Mori, H; Tanaka, T; Yamahara, J | 1 |
| Esumi, H; Minamoto, T; Onda, M; Yamashita, N | 1 |
| Bird, RP; Magnuson, BA; Shirtliff, N | 1 |
| Kawamori, T; Kojima, T; Mori, H; Ohnishi, M; Suzui, M; Tanaka, T | 1 |
| Corpet, DE; Goubet, I; Pirot, V | 1 |
| Amin, S; Desai, D; Kulkarni, N; Rao, CV; Reddy, BS; Simi, B | 1 |
| Bird, RP; Carr, I; Magnuson, BA | 1 |
| Bird, RP; Magnuson, BA | 1 |
| Mori, H; Reddy, BS; Sugie, S; Tanaka, T | 1 |
| Bird, RP; Stopera, SA | 1 |
| Archer, MC; Bruce, WR; Chan, CC; Minkin, S; Stamp, D; Zhang, XM | 1 |
| Archer, MC; Bruce, WR; Medline, A; Stamp, D; Zhang, XM | 1 |
| O'Riordan, MA; Pretlow, TG; Pretlow, TP; Spancake, KM | 1 |
| Mori, H; Okamoto, K; Reddy, BS; Satoh, K; Sugie, S; Tanaka, T | 1 |
| Fukutake, M; Ishida, K; Sugimura, T; Takahashi, M; Wakabayashi, K; Yokota, S | 1 |
| Alexander, J; Paulsen, JE; Steffensen, IL | 1 |
| Iwamoto, Y; Kendall, CW; Rao, AV; Sugano, M; Torzsas, TL | 1 |
| Aliaga, C; Patel, N; Rao, CV; Reddy, BS; Simi, B | 1 |
| Hirose, Y; Kawamori, T; Mori, H; Ohnishi, M; Tanaka, T | 1 |
| Barnes, LH; Kelloff, GV; Lubet, RA; Pereira, MA; Steele, VE | 1 |
| Alabaster, O; Shivapurkar, N; Tang, Z | 2 |
| Bird, RP; Good, CK; Lasko, CM; Yao, K | 1 |
| Kawamori, T; Komaki, C; Mori, H; Moriwaki, H; Muto, Y; Okuno, M; Onogi, N; Tanaka, T | 1 |
| Barnes, LH; Eto, I; Grubbs, CJ; Juliana, M; Kelloff, GJ; Li, H; Lubet, RA; Olson, GR; Pereira, MA; Steele, VE; Whitaker, LM | 1 |
| Hara, A; Hirose, Y; Maeda, M; Makita, H; Mori, H; Satoh, K; Tanaka, T; Toriyama, HB; Tsuda, H; Yang, M | 1 |
| Bird, RP; Shirtliff, N | 1 |
| Rao, CV; Reddy, BS; Seibert, K | 1 |
| Bird, RP; Latta, M; Yao, K | 1 |
| Challa, A; Chawan, CB; Rao, DR; Shackelford, L | 1 |
| Corpet, DE; Preclaire, M; Taché, S | 1 |
| Chatelin-Pirot, V; Corpet, DE | 1 |
| Koratkar, R; Rao, AV | 1 |
| Hara, A; Kawabata, K; Kawamori, T; Koshimizu, K; Makita, H; Mori, H; Murakami, A; Ohigashi, H; Satoh, K; Tanaka, T | 1 |
| Fukuda, K; Fukutake, M; Isoi, T; Sato, H; Sugimura, T; Takahashi, M; Wakabayashi, K; Yazawa, K | 1 |
| Li, K; Pereira, MA; Tao, L | 1 |
| Kelloff, GJ; Kramer, PM; Lubet, RA; Olson, G; Pereira, MA; Steele, VE; Zheng, Y | 1 |
| Hara, A; Kakumoto, M; Kawabata, K; Koshimizu, K; Kuki, W; Makita, H; Mori, H; Murakami, A; Ohigashi, H; Satoh, K; Takahashi, Y; Tanaka, T; Yonei, H | 1 |
| Hara, A; Kawabata, K; Matsunaga, K; Mori, H; Yamada, Y; Yoshimi, N | 1 |
| Coutts, JT; Lievense, LC; Rowland, IR; Rumney, CJ | 1 |
| Kelloff, GJ; Kramer, PM; Li, H; Lubet, RA; Pereira, MA; Steele, VE | 2 |
| Hori, T; Matsumoto, K; Morotomi, M; Sakaitani, Y; Sato, M | 1 |
| Exon, JH; Hendrix, K; Magnuson, BA; South, EH | 3 |
| Baba-Toriyama, H; Iigo, M; Kakizoe, T; Kuhara, T; Moore, MA; Murakoshi, M; Nishino, H; Satomi, Y; Sekine, K; Tsuda, H; Ushida, Y | 1 |
| Bazzicalupo, M; Briani, C; Caderni, G; De Filippo, C; Dolara, P; Fazi, M; Giannini, A | 1 |
| Binasco, V; Caderni, G; Premoselli, F; Sesca, E; Tessitore, L | 1 |
| Amagaya, S; Fukuda, K; Fukutake, M; Iizuka, A; Kawamura, H; Komatsu, Y; Yokota, S | 1 |
| Delker, DA; Papanikolaou, A; Rosenberg, DW; Wang, QS | 1 |
| Asamoto, M; Baba-Toriyama, H; Kakizoe, T; Kim, DJ; Kuhara, T; Moore, MA; Nakamura, J; Nishino, H; Sekine, K; Takasuka, N; Tsuda, H; Ushida, Y | 1 |
| Davies, MJ; Rumsby, PC | 1 |
| Reddy, BS | 1 |
| Hirabayashi, N; Ikegami, T; Kano, M; Matsuzaki, Y; Shoda, J; Tanaka, N | 1 |
| Kelloff, GJ; Kramer, PM; Lubet, RA; Pereira, MA; Steele, VE; Zheng, Y | 1 |
| Conran, P; Hawk, EE; Kelloff, GJ; Kramer, PM; Li, H; Lubet, RA; Pereira, MA; Schut, HA; Steele, VE | 1 |
| Indranie, C; Rao, CV; Reddy, BS; Sanders, ME; Simi, B | 1 |
| Hamid, R; Kawamori, T; Rao, CV; Reddy, BS | 1 |
| Adam, J; Bird, RP; Good, CK; Lasko, CM | 1 |
| Delker, DA; Papanikolaou, A; Rosenberg, DW; Wang, QS; Whiteley, HE | 1 |
| Baijal, PK; Bird, RP; Clow, EP; Fitzpatrick, DW | 1 |
| Corpet, DE; Parnaud, G | 1 |
| Di Betta, E; Fontana, MG; Ghirardi, M; Nascimbeni, R; Salerni, B; Villanacci, V | 1 |
| Hara, A; Honjo, S; Kakumoto, M; Kawabata, K; Makita, H; Mori, H; Tanaka, T; Tsuda, H; Ushida, J | 1 |
| Azuma, N; Iwami, K; Kanamoto, R; Kanaya, M | 1 |
| Arimochi, H; Chewonarin, T; Kataoka, K; Kinouchi, T; Kuwahara, T; Ohnishi, Y; Vinitketkumnuen, U | 1 |
| Kawamori, T; Kondo, K; Maruyama, T; Nakatsugi, S; Narumiya, S; Ohta, T; Ohuchida, S; Sugimura, T; Ushikubi, F; Wakabayashi, K; Watanabe, K; Yamamoto, H | 1 |
| Corpet, DE; Parnaud, G; Peiffer, G; Taché, S | 1 |
| Kawamori, T; Nakatsugi, S; Ohta, T; Sugimura, T; Takahashi, M; Wakabayashi, K; Watanabe, K | 1 |
| Bollito, E; Caderni, G; Tessitore, L | 1 |
| Given, R; Singh, P; Varro, A; Velasco, M; Wang, TC; Wargovich, M | 1 |
| Campart, GB; Carrozzino, R; Ghia, M; Martelli, A; Mattioli, F; Mereto, E; Orsi, P; Puglia, CP | 1 |
| Duranton, B; Ellmerich, S; Galluser, M; Gossé, F; Klein, JP; Raul, F; Schöller, M | 1 |
| Kawamori, T; Kondo, K; Maruyama, T; Nakatsugi, S; Narumiya, S; Ohta, T; Ohuchida, S; Sugimura, T; Wakabayashi, K; Watanabe, K; Yamamoto, H | 1 |
| Corpet, DE; Delverdier, M; Parnaud, G; Peiffer, G; Taché, S | 1 |
| Azuma, N; Iwami, K; Kanamoto, R; Machida, K; Saeki, T | 1 |
| Kawamori, T; Mutoh, M; Sugimura, T; Takahashi, M; Wakabayashi, K | 1 |
| Amagaya, S; Fukuda, K; Fukutake, M; Iijima, O; Ishige, A; Ishikawa, H; Komatsu, Y; Kubo, M; Miura, N; Okada, M; Sasaki, H; Wakabayashi, K; Yamamoto, M | 1 |
| Hara, A; Kawabata, K; Matsunaga, K; Mori, H; Shimizu, M; Tanaka, T; Yamada, Y; Yamamoto, T | 1 |
| Hara, A; Hirose, Y; Kawabata, K; Matsunaga, K; Mori, H; Shimizu, M; Yamada, Y; Yoshimi, N | 1 |
| Brown, RE; Carroll, RJ; Chang, WC; Chapkin, RS; Davidson, LA; Lupton, JR; Morris, JS; Turner, ND; Wang, N | 1 |
| Jenab, M; Thompson, LU | 1 |
| Papanikolaou, A; Papanikolaou, D; Rosenberg, DW; Wang, QS; Whiteley, HE | 1 |
| Caderni, G; Davit, A; Sarotto, I; Tessitore, L | 1 |
| Nambiar, PR; Papanikolaou, A; Rosenberg, DW; Wang, QS | 1 |
| Fan, K; Kelloff, GJ; Lamprecht, SA; Leung, D; Lipkin, M; Liu, Y; Newmark, H; Shinozaki, H; Steele, VE; Yang, K | 1 |
| Caderni, G; De Filippo, C; Dolara, P; Gambacciani, L; Giannini, A; Luceri, C; Salvadori, M | 1 |
| Katoh, O; Masaoka, Y; Watanabe, H | 1 |
| Baines, AT; Basye, JL; Bhattacharyya, AK; Clark, LC; Cui, H; Earnest, DL; Holubec, H; Nelson, MA; Roe, D; Shriver, B; Spallholz, J; Thorne, P | 1 |
| Dashwood, RH; Exon, JH; Hendrix, K; Hubele, S; Magnuson, BA; South, EH; Xu, M | 1 |
| Le Leu, RK; McIntosh, GH; Young, GP | 1 |
| Bergmann, C; Duranton, B; Gossé, F; Raul, F; Schleiffer, R | 1 |
| Corpet, DE; Millet, AS; Peiffer, G; Taché, S | 1 |
| Iijima, H; Kobayashi, H; Matsunaga, K | 1 |
| Bruijntjes, JB; Hollanders, VM; Schoterman, HC; Wijnands, MV; Woutersen, RA | 1 |
| Kagami, S; Kohno, H; Maeda, M; Miyake, M; Murakami, M; Tanaka, T; Wada, K | 1 |
| Hara, A; Katayama, M; Kuno, T; Matsunaga, K; Mori, H; Qiao, Z; Yamada, Y; Yamahara, J; Yoshimi, N | 1 |
| Fields, AP; Gatalica, Z; Gökmen-Polar, Y; Murray, NR; Velasco, MA | 1 |
| Hirose, Y; Indranie, C; Rao, CV; Reddy, BS | 1 |
| Arimochi, H; Chiampanichayakul, S; Kataoka, K; Kuwahara, T; Nakayama, H; Ohnishi, Y; Thumvijit, S; Vinitketkumnuen, U | 1 |
| Hosokawa, M; Kohno, H; Murakami, A; Okumura, A; Takashima, S; Tanaka, T; Yoshitani, S | 1 |
| Anton, R; Gossé, F; Lobstein, A; Metz, N; Raul, F; Schleiffer, R; Schneider, Y | 1 |
| Hosokawa, M; Kohno, H; Okumura, A; Takashima, S; Tanaka, T; Yamaguchi, N; Yoshitani , S | 1 |
| Hara, A; Hirose, Y; Katayama, M; Kuno, T; Mori, H; Qiao, Z; Shimizu, M; Yamada, Y; Yoshimi, N | 1 |
| Alexander, J; Husøy, T; Løberg, EM; Namork, E; Paulsen, JE; Steffensen, IL | 1 |
| Imai, H; Kawamori, T; Nakagama, H; Ochiai, M; Sugimura, T; Ubagai, T | 1 |
| Boggio, M; Borrelli, F; Capasso, F; Izzo, AA; Mascolo, N; Massa, B; Mereto, E; Orsi, P; Sini, D | 1 |
| Kohno, H; Koshimizu, K; Mori, H; Murakami, A; Ohigashi, H; Safitri, R; Shimizu, M; Takahashi, D; Tanaka, T; Tsukio, Y; Yamamoto, K; Yoshitani, S | 1 |
| Fiala, ES; Gonzalez, FJ; Requeijo, SP; Sohn, OS; Weisburger, JH | 1 |
| Aly, A; Baldwin, GS; Shulkes, A | 1 |
| Beppu, H; Chihara, T; Ida, C; Kaneko, T; Kuzuya, H; Nagatsu, T; Shimpo, K | 1 |
| Meline, B; Singletary, KW | 1 |
| Kawamori, T; Kitamura, T; Kobayashi, K; Kobayashi, M; Maruyama, T; Mutoh, M; Narumiya, S; Ohuchida, S; Shoji, Y; Sugimoto, Y; Sugimura, T; Takahashi, M; Tani, K; Wakabayashi, K; Watanabe, K | 1 |
| Hara, Y; Hasegawa, J; Isemura, M; Kishimoto, Y; Kohri, T; Miura, N; Ohishi, T; Shiota, G | 1 |
| Arika, T; Asano, R; Baba, M; Nishino, H; Ohmura, M; Okada, Y; Okuyama, T; Sugimoto, H; Takahashi, T; Takigami, I | 1 |
| Hosokawa, M; Kohno, H; Miyashita, K; Noguchi, R; Suzuki, R; Tanaka, T | 1 |
| Caderni, G; Cecchini, F; Perrelli, MG; Tessitore, L | 1 |
| Hara, A; Hirose, Y; Katayama, M; Kuno, T; Mori, H; Saji, S; Sakata, K; Yamada, Y | 1 |
| Archer, MC; Ealey, KN; el-Sohemy, A | 1 |
| Buzzigoli, C; Caderni, G; Cocca, E; Dolara, P; Femia, AP; Salvadori, M | 1 |
| Williamson, RC | 1 |
| Pozharisskiĭ, KM | 1 |
| Alabaster, O; Shivapurkar, N; Tang, ZC | 1 |
| Amini, SB; O'Riordan, MA; Pretlow, TG; Pretlow, TP; Somich, GA | 1 |
| Bird, RP; Murphy, LC; Stopera, SA | 1 |
| Kendall, CW; Koo, M; Rao, AV; Sokoloff, E | 1 |
| Archer, MC; Bruce, WR; Chan, CC; Corpet, DE; Medline, A; Roncucci, L; Stamp, D; Zhang, XM | 1 |
| Friday, D; Janezic, SA; Kendall, CW; Rao, AV | 2 |
| Floyd, J; Golightly, S; Gordon, GB; Hamilton, SR | 1 |
| Khoury, MD; Pereira, MA | 1 |
| Bird, RP; McLellan, E | 1 |
| Deschner, EE; Lupton, JR; Newmark, HL; Ruperto, JF | 1 |
| Carr, K; Galloway, DJ; George, WD; Indran, M; Jarrett, F | 1 |
| Bird, RP; McLellan, EA | 1 |
| Cooke, T; Matthews, J | 1 |
| Goeting, NL; Taylor, I; Trotter, GA | 1 |
6 review(s) available for azoxymethane and Precancerous Conditions
| Article | Year |
|---|---|
Azoxymethane-induced rat aberrant crypt foci: relevance in studying chemoprevention of colon cancer.
Topics: Animals; Azoxymethane; Biomarkers, Tumor; Carcinogens; Chemoprevention; Colon; Colonic Neoplasms; Disease Models, Animal; Humans; Precancerous Conditions; Rats | 2008 |
Morphological and molecular alterations in 1,2 dimethylhydrazine and azoxymethane induced colon carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Azoxymethane; Biomarkers, Tumor; Colonic Neoplasms; Humans; Precancerous Conditions; Rats; Terminology as Topic | 2011 |
Counterpoint: From animal models to prevention of colon cancer. Criteria for proceeding from preclinical studies and choice of models for prevention studies.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Chemoprevention; Colonic Neoplasms; Diet; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Mice; Mice, Mutant Strains; Precancerous Conditions; Randomized Controlled Trials as Topic; Rats | 2003 |
Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Chemoprevention; Colonic Neoplasms; Diet; Disease Models, Animal; Humans; Mice; Mice, Mutant Strains; Precancerous Conditions; Randomized Controlled Trials as Topic; Rats | 2003 |
Role of aberrant crypt foci in understanding the pathogenesis of colon cancer.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Cholic Acid; Cholic Acids; Colon; Colonic Neoplasms; Dietary Fats; Dimethylhydrazines; Genes, ras; Humans; Intestinal Mucosa; Precancerous Conditions | 1995 |
[Successes of experimental oncology and problems of the study of the morphogenesis of tumors].
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Aflatoxins; Animals; Azoxymethane; Benzopyrenes; Brain Neoplasms; Carcinogens; Cricetinae; Dimethylhydrazines; Dogs; Esophageal Neoplasms; Ethionine; Ethylnitrosourea; Female; Hematopoietic System; Intestinal Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosamines; Nitroso Compounds; Nitrosoguanidines; o-Aminoazotoluene; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Skin Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms | 1975 |
289 other study(ies) available for azoxymethane and Precancerous Conditions
| Article | Year |
|---|---|
Protective Role of Spermidine in Colitis and Colon Carcinogenesis.
Topics: Adenomatous Polyposis Coli Protein; alpha-Defensins; Animals; Azoxymethane; Carcinogenesis; Colitis; Colitis, Ulcerative; Colon; Colonic Neoplasms; Dextran Sulfate; Gastrointestinal Microbiome; Gene Expression Regulation; Humans; Intestinal Mucosa; Male; Mice; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Precancerous Conditions; Protective Factors; RNA, Messenger; Severity of Illness Index; Spermidine; Weight Loss | 2022 |
Dietary Energy Intake and Presence of Aberrant Crypt Foci Are Associated with Phospholipid, Purine, and Taurine Metabolite Abundances in C57BL/6N Mouse Colon.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Diet; Energy Intake; Mice; Mice, Inbred C57BL; Phospholipids; Precancerous Conditions; Purines; Taurine | 2022 |
Effects of high-fat diet and intestinal aryl hydrocarbon receptor deletion on colon carcinogenesis.
Topics: Animals; Azoxymethane; Basic Helix-Loop-Helix Transcription Factors; beta Catenin; Cell Proliferation; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Diet, High-Fat; Disease Models, Animal; DNA Damage; Epithelial Cells; Gene Deletion; Gene Expression Regulation, Neoplastic; Intestinal Mucosa; Mice, Inbred C57BL; Mice, Knockout; Precancerous Conditions; Receptors, Aryl Hydrocarbon; Signal Transduction | 2020 |
Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation.
Topics: Adaptor Proteins, Signal Transducing; Adenomatous Polyposis Coli; Animals; Azoxymethane; Carcinogenesis; Cell Adhesion Molecules; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Focal Adhesion Protein-Tyrosine Kinases; Humans; Inflammation; Integrins; Interleukin-6; Intestines; Mice, Inbred C57BL; Myofibroblasts; Precancerous Conditions; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Stromal Cells; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins | 2020 |
Alpha-Glucosidase Inhibitor Voglibose Suppresses Azoxymethane-Induced Colonic Preneoplastic Lesions in Diabetic and Obese Mice.
Topics: Animals; Antioxidants; Azoxymethane; Biomarkers; Biopsy; Cell Proliferation; Colonic Neoplasms; Cytokines; Diabetes Mellitus, Type 2; Disease Models, Animal; Glycoside Hydrolase Inhibitors; Humans; Inflammation Mediators; Inositol; Intestinal Mucosa; Mice; NF-kappa B; Obesity; Oxidative Stress; Precancerous Conditions | 2020 |
Zinc dyshomeostasis in azoxymethane-induced colonic precancerous and cancerous lesions in Fischer rats.
Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Male; Precancerous Conditions; Rats, Inbred F344; Zinc | 2021 |
Chemopreventive effects of Ku-jin tea against AOM-induced precancerous colorectal lesions in rats and metabolomic analysis.
Topics: Animals; Azoxymethane; Body Weight; Chemoprevention; Colon; Colorectal Neoplasms; Cytokines; Discriminant Analysis; Immunologic Factors; Least-Squares Analysis; Male; Metabolic Networks and Pathways; Metabolomics; Precancerous Conditions; Rats, Wistar; Tea | 2017 |
Methylglyoxal displays colorectal cancer-promoting properties in the murine models of azoxymethane and CT26 isografts.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Cell Line; Cholesterol, LDL; Colorectal Neoplasms; Disease Models, Animal; Humans; Inflammation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Oxidative Stress; Precancerous Conditions; Pyruvaldehyde; Transplantation, Isogeneic | 2018 |
Gum arabic and red propolis protecteting colorectal preneoplastic lesions in a rat model of azoxymethane1.
Topics: Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Disease Models, Animal; Gum Arabic; Lysine; Male; Oxidative Stress; Precancerous Conditions; Propolis; Rats; Rats, Wistar | 2019 |
Enhanced development of azoxymethane-induced colonic preneoplastic lesions in hypertensive rats.
Topics: Adipose Tissue; Angiotensin II; Animals; Azoxymethane; Carcinogens; Catalase; Chemokine CCL2; Colorectal Neoplasms; Cyclooxygenase 2; Glutathione Peroxidase; Hypertension; Insulin Resistance; Interleukin-6; Intestinal Mucosa; Male; Nitric Oxide Synthase Type II; Oxidative Stress; Precancerous Conditions; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Zucker; RNA, Messenger; Tumor Necrosis Factor-alpha | 2013 |
Deletion of glutathione peroxidase-2 inhibits azoxymethane-induced colon cancer development.
Topics: Adenoma; Animals; Antioxidants; Apoptosis; Azoxymethane; beta Catenin; Carcinogenesis; Colonic Neoplasms; Diet; Dietary Supplements; Epithelial Cells; Gene Deletion; Glutathione Peroxidase; Humans; Intestinal Mucosa; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Selenium | 2013 |
Comparing the effects of COX and non-COX-inhibiting NSAIDs on enhancement of apoptosis and inhibition of aberrant crypt foci formation in a rat colorectal cancer model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azoxymethane; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Disease Models, Animal; Flurbiprofen; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Sulindac | 2013 |
Inhibition of beta-catenin and KRAS expressions by Piper betle in azoxymethane-induced colon cancer of male Fischer 344 rats.
Topics: Animals; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Disease Models, Animal; Immunohistochemistry; Male; Phytotherapy; Piper betle; Plant Extracts; Plant Leaves; Precancerous Conditions; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Rats; Rats, Inbred F344 | 2013 |
Canola oil influence on azoxymethane-induced colon carcinogenesis, hypertriglyceridemia and hyperglycemia in Kunming mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colonic Neoplasms; Fatty Acids, Monounsaturated; Female; Hyperglycemia; Hypertriglyceridemia; Male; Mice; Organ Size; Precancerous Conditions; Rapeseed Oil | 2014 |
[Changes of expression of miR-155 in colitis-associated colonic carcinogenesis].
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Cocarcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Gene Expression Profiling; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Precancerous Conditions; Up-Regulation | 2014 |
Aldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice.
Topics: Aldehyde Reductase; Animals; Anticarcinogenic Agents; Azoxymethane; Colon; Colonic Neoplasms; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; HT29 Cells; Humans; Imidazolidines; Inflammation Mediators; Intestinal Mucosa; Male; Mice, Inbred C57BL; Obesity; Oxidative Stress; Precancerous Conditions; Signal Transduction | 2014 |
Inhibitory effects of astaxanthin on azoxymethane-induced colonic preneoplastic lesions in C57/BL/KsJ-db/db mice.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Azoxymethane; beta Catenin; Cell Proliferation; Colonic Neoplasms; Inflammation Mediators; Intestinal Mucosa; Male; Mice, Inbred C57BL; NF-kappa B; Obesity; Oxidative Stress; Precancerous Conditions; Xanthophylls | 2014 |
Oral concentrated grape juice suppresses expression of NF-kappa B, TNF-α and iNOS in experimentally induced colorectal carcinogenesis in Wistar rats.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Carcinogens; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Gene Expression Regulation, Neoplastic; Humans; Male; NF-kappa B; Phytotherapy; Plant Extracts; Precancerous Conditions; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vitis | 2015 |
Unpolished Thai rice prevents ACF formation and dysplastic progression in AOM-induced rats and induces apoptosis through redox alteration in CaCo-2 cells.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Caco-2 Cells; Carcinogens; Cell Proliferation; Colonic Neoplasms; Diet; Disease Progression; Flow Cytometry; Humans; Male; Oryza; Oxidation-Reduction; Oxidative Stress; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 2015 |
Chemopreventive effect of Phaleria macrocarpa on colorectal cancer aberrant crypt foci in vivo.
Topics: Animals; Antioxidants; Azoxymethane; bcl-2-Associated X Protein; Body Weight; Carcinogens; Colorectal Neoplasms; Female; HT29 Cells; Humans; Male; Plant Extracts; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Thymelaeaceae | 2016 |
Unpolished Thai Rice Prevents Aberrant Crypt Foci Formation through the Invovement of ?catenin and COX2 Expression in AzoxymethaneTreated Rats.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Biomarkers; Catenins; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase 2; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-6; Male; Oryza; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Thailand | 2016 |
Activins and their related proteins in colon carcinogenesis: insights from early and advanced azoxymethane rat models of colon cancer.
Topics: Activins; Adenocarcinoma; Animals; Azoxymethane; Biomarkers, Tumor; Carcinogenesis; Colonic Neoplasms; Disease Progression; Follistatin; Gene Expression; Male; Precancerous Conditions; Rats, Wistar | 2016 |
Effects of resistant starch on colonic preneoplastic aberrant crypt foci in rats.
Topics: Animals; Azoxymethane; Body Weight; Carcinogens; Cecum; Colon; Colonic Neoplasms; Diet; Dietary Fiber; Eating; Feces; Gastrointestinal Transit; Hydrogen-Ion Concentration; Intestinal Mucosa; Male; Organ Size; Precancerous Conditions; Rats; Rats, Wistar; Solanum tuberosum; Starch | 2008 |
Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition.
Topics: Adiponectin; AMP-Activated Protein Kinase Kinases; Animals; Apoptosis; Azoxymethane; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Polyps; Colorectal Neoplasms; Dietary Fats; Intestinal Mucosa; Mice; Mice, Knockout; Obesity; Precancerous Conditions; Protein Biosynthesis; Protein Kinases; Receptors, Adiponectin; TOR Serine-Threonine Kinases | 2008 |
Dark Aberrant Crypt Foci with activated Wnt pathway are related to tumorigenesis in the colon of AOM-treated rat.
Topics: Animals; Azoxymethane; beta Catenin; Carcinogens; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; Matrix Metalloproteinase 7; Precancerous Conditions; Rats; Rats, Wistar; Signal Transduction; Wnt Proteins | 2008 |
Aqueous and ethanolic extract fractions from the Brazilian propolis suppress azoxymethane-induced aberrant crypt foci in rats.
Topics: Animals; Anti-Infective Agents; Azoxymethane; Carcinogens; Colonic Neoplasms; Ethanol; Immunoenzyme Techniques; Male; Plant Extracts; Precancerous Conditions; Propolis; Rats; Rats, Wistar | 2008 |
Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer.
Topics: Animals; Azoxymethane; Biomarkers; Brain Chemistry; Carcinogens; Carrier Proteins; Colitis; Colonic Neoplasms; Dextran Sulfate; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Deficiency; Food, Formulated; Heterozygote; Homocysteine; Intestinal Mucosa; Membrane Transport Proteins; Mice; Mice, Knockout; Models, Animal; Nutritional Status; Precancerous Conditions; Receptors, Cell Surface; Reduced Folate Carrier Protein | 2009 |
Citrus compounds inhibit inflammation- and obesity-related colon carcinogenesis in mice.
Topics: Animals; Azoxymethane; Citrus; Colitis; Colonic Neoplasms; Coumarins; Cyclooxygenase 2; Interleukin-1beta; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Obesity; Precancerous Conditions; Tumor Necrosis Factor-alpha | 2008 |
Aldose reductase deficiency in mice prevents azoxymethane-induced colonic preneoplastic aberrant crypt foci formation.
Topics: Aldehyde Reductase; Animals; Azoxymethane; Colonic Neoplasms; DNA Primers; Lipid Peroxidation; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Precancerous Conditions; Protein Kinase C; Protein Kinase C beta; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
An n-3 PUFA-rich microalgal oil diet protects to a similar extent as a fish oil-rich diet against AOM-induced colonic aberrant crypt foci in F344 rats.
Topics: Animal Feed; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Corn Oil; Dietary Fats; Disease Models, Animal; Eukaryota; Fatty Acids, Omega-3; Fish Oils; Intestinal Mucosa; Male; Oxidative Stress; Plant Oils; Precancerous Conditions; Rats; Rats, Inbred F344 | 2009 |
Elevated circulating adiponectin and elevated insulin sensitivity in adiponectin transgenic mice are not associated with reduced susceptibility to colon carcinogenesis.
Topics: Adiponectin; Animals; Azoxymethane; Carcinogens; Cells, Cultured; Colon; Colonic Neoplasms; Disease Susceptibility; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Male; Mice; Mice, Transgenic; Precancerous Conditions; Weight Gain | 2009 |
(-)-Epigallocatechin gallate suppresses azoxymethane-induced colonic premalignant lesions in male C57BL/KsJ-db/db mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinoma; Catechin; Cholesterol; Colonic Neoplasms; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Insulin; Intestinal Mucosa; Leptin; Male; Mice; Mice, Inbred C57BL; Precancerous Conditions; Receptor, IGF Type 1; Triglycerides | 2008 |
Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Carcinogens; Carcinoma; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Intestinal Mucosa; Male; Nitric Oxide Synthase Type II; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Silybin; Silymarin | 2008 |
Inflammation-associated serum and colon markers as indicators of dietary attenuation of colon carcinogenesis in ob/ob mice.
Topics: Animals; Azoxymethane; Biomarkers, Tumor; Carcinogens; Colonic Neoplasms; Cytokines; Diet; Fabaceae; Gene Expression; Inflammation; Interleukin-6; Male; Mice; Mice, Obese; Obesity; Phytotherapy; Plant Extracts; Precancerous Conditions; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Fatty acid synthase is over-expressed in large aberrant crypt foci in rats treated with azoxymethane.
Topics: Animals; Azoxymethane; Cell Nucleus; Colonic Neoplasms; Fatty Acid Synthases; Immunohistochemistry; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 2009 |
Egg yolk proteins suppress azoxymethane-induced aberrant crypt foci formation and cell proliferation in the colon of rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Bromodeoxyuridine; Carcinogens; Caseins; Cecum; Cell Proliferation; Colon; Colonic Neoplasms; DNA; Egg Proteins; Fatty Acids, Volatile; Intestinal Mucosa; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 2009 |
Supplementation with branched-chain amino acids inhibits azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db mice.
Topics: Amino Acids, Branched-Chain; Animals; Azoxymethane; beta Catenin; Body Weight; Carcinogens; Colonic Neoplasms; Diabetes Mellitus, Experimental; Dietary Supplements; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Obesity; Organ Size; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Receptor, IGF Type 1; Receptor, IGF Type 2; Tumor Cells, Cultured | 2009 |
Inhibition of colon carcinogenesis by post-initiation induction of NQO1 in Sprague-Dawley rats.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Enzyme Induction; Glucuronosyltransferase; Glutathione Transferase; Intestinal Mucosa; Male; NAD(P)H Dehydrogenase (Quinone); Neoplasms, Experimental; Precancerous Conditions; Pyrazines; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes; Time Factors | 2009 |
Mucin-depleted foci show strong activation of inflammatory markers in 1,2-dimethylhydrazine-induced carcinogenesis and are promoted by the inflammatory agent sodium dextran sulfate.
Topics: 1,2-Dimethylhydrazine; Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Inflammation; Male; Mucin-2; Nitric Oxide Synthase Type II; Precancerous Conditions; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2009 |
Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon.
Topics: Animals; Apoptosis; Aurora Kinase B; Aurora Kinases; Azoxymethane; Blotting, Western; Cannabinoid Receptor Antagonists; Cell Cycle; Cell Proliferation; Checkpoint Kinase 1; Chromosome Aberrations; Colony-Forming Units Assay; Colorectal Neoplasms; Cyclin B; Cyclin B1; DNA Damage; Female; Humans; Mice; Mice, Inbred C57BL; Mitotic Index; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Polyploidy; Precancerous Conditions; Protein Kinases; Protein Serine-Threonine Kinases; Pyrazoles; Rimonabant; Tumor Cells, Cultured | 2009 |
Long-term ingestion of reduced glutathione suppressed an accelerating effect of beef tallow diet on colon carcinogenesis in rats.
Topics: Animals; Antioxidants; Arachidonic Acid; Azoxymethane; beta Catenin; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Cyclooxygenase 2; Disease Models, Animal; Fats; Glutathione; Glutathione Reductase; Intestinal Mucosa; Male; Oxidative Stress; Precancerous Conditions; Random Allocation; Rats; Rats, Sprague-Dawley | 2009 |
Chemopreventive efficacy of naproxen and nitric oxide-naproxen in rodent models of colon, urinary bladder, and mammary cancers.
Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Butylhydroxybutylnitrosamine; Carcinogens; Colonic Neoplasms; Diet; Female; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Naproxen; Nitric Oxide Donors; Precancerous Conditions; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Urinary Bladder Neoplasms | 2009 |
Dietary flavonoids suppress azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db mice.
Topics: Animals; Antioxidants; Azoxymethane; Carcinogens; Colonic Neoplasms; Dietary Supplements; Flavones; Flavonoids; Insulin; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Precancerous Conditions; Quercetin | 2010 |
Conjugated linoleic acid suppresses colon carcinogenesis in azoxymethane-pretreated rats with long-term feeding of diet containing beef tallow.
Topics: Animals; Apoptosis; Arachidonic Acid; Azoxymethane; Cattle; Cell Proliferation; Colonic Neoplasms; Dietary Fats; Fats; Linoleic Acids, Conjugated; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Wnt Proteins | 2010 |
Resveratrol from transgenic alfalfa for prevention of aberrant crypt foci in mice.
Topics: Animals; Azoxymethane; Body Weight; Chromatography, High Pressure Liquid; Colonic Neoplasms; Eating; Female; Glucosides; Lactase-Phlorizin Hydrolase; Medicago sativa; Mice; Plants, Genetically Modified; Precancerous Conditions; Resveratrol; Stilbenes | 2010 |
Chlorogenic acid differentially alters hepatic and small intestinal thiol redox status without protecting against azoxymethane-induced colon carcinogenesis in mice.
Topics: Animals; Azoxymethane; Body Weight; Chlorogenic Acid; Colonic Neoplasms; Eating; Glutathione; Intestine, Small; Liver; Mice; Oxidation-Reduction; Precancerous Conditions; Sulfhydryl Compounds | 2010 |
Pitavastatin inhibits azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db obese mice.
Topics: Animals; Azoxymethane; Carcinogens; Cell Division; Colonic Neoplasms; Cytokines; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Precancerous Conditions; Quinolines | 2010 |
Freeze-dried ham promotes azoxymethane-induced mucin-depleted foci and aberrant crypt foci in rat colon.
Topics: Animals; Azoxymethane; Colonic Neoplasms; Female; Freeze Drying; Hemin; Lipid Peroxidation; Meat Products; Mucins; Precancerous Conditions; Rats; Rats, Inbred F344; Swine | 2010 |
The NSAID sulindac is chemopreventive in the mouse distal colon but carcinogenic in the proximal colon.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Drug Evaluation, Preclinical; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation Mediators; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Knockout; MutS Homolog 2 Protein; Precancerous Conditions; Sulindac; Tumor Suppressor Protein p53 | 2011 |
Renin-angiotensin system inhibitors suppress azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db obese mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Azoxymethane; Benzimidazoles; Benzoates; Captopril; Colonic Neoplasms; Cyclooxygenase 2; Deoxyguanosine; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Obesity; Oxidative Stress; Plasminogen Activator Inhibitor 1; Precancerous Conditions; Renin-Angiotensin System; RNA, Messenger; Telmisartan; Tumor Necrosis Factor-alpha | 2011 |
Inhibition of azoxymethane-induced preneoplastic lesions in the rat colon by a cooked stearic acid complexed high-amylose cornstarch.
Topics: Amylose; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Diet; Fatty Acids, Volatile; Hot Temperature; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Starch; Stearic Acids | 2011 |
Chemoprevention of colon cancer in a rat carcinogenesis model using a novel nanotechnology-based combined treatment system.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Azoxymethane; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Drug Delivery Systems; Folic Acid; Lactic Acid; Male; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Vitamin B Complex | 2011 |
Cocoa-rich diet prevents azoxymethane-induced colonic preneoplastic lesions in rats by restraining oxidative stress and cell proliferation and inducing apoptosis.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; bcl-2-Associated X Protein; Cacao; Caspase 3; Cell Proliferation; Colon; Colonic Neoplasms; Cyclin D1; Diet; Gene Expression Regulation; Oxidative Stress; Precancerous Conditions; Rats | 2011 |
Anti-carcinogenic properties of omeprazole against human colon cancer cells and azoxymethane-induced colonic aberrant crypt foci formation in rats.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cell Growth Processes; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; HCT116 Cells; Humans; Male; Omeprazole; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344 | 2012 |
Preventive effects of curcumin on the development of azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db obese mice.
Topics: Adiponectin; Adipose Tissue; AMP-Activated Protein Kinase Kinases; Animals; Anticarcinogenic Agents; Azoxymethane; Colon; Colonic Neoplasms; Curcumin; Cyclooxygenase 2; Dietary Supplements; Interleukin-6; Intestinal Mucosa; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; NF-kappa B; Obesity; Organ Size; Precancerous Conditions; Protein Kinases; Tumor Necrosis Factor-alpha | 2012 |
Monosodium glutamate-induced diabetic mice are susceptible to azoxymethane-induced colon tumorigenesis.
Topics: Animals; Azoxymethane; Colonic Neoplasms; Diabetes Mellitus, Experimental; Disease Models, Animal; Disease Susceptibility; Hypercholesterolemia; Hyperglycemia; Hyperinsulinism; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred ICR; Precancerous Conditions; Receptor, IGF Type 1; RNA, Messenger; Sodium Glutamate | 2012 |
Suppression of azoxymethane-induced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2,3-dioxygenase.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colonic Neoplasms; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Tryptophan | 2012 |
Metabonomic variations associated with AOM-induced precancerous colorectal lesions and resveratrol treatment.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Colorectal Neoplasms; Male; Metabolome; Precancerous Conditions; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2012 |
Genistein, a soya isoflavone, prevents azoxymethane-induced up-regulation of WNT/β-catenin signalling and reduces colon pre-neoplasia in rats.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Biomarkers; Carcinogens; Colon, Descending; Colonic Neoplasms; Cyclin D1; Disease Models, Animal; Down-Regulation; Female; Genistein; Lactation; Male; Maternal Nutritional Physiological Phenomena; Precancerous Conditions; Pregnancy; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley; Soybean Proteins; Wnt Signaling Pathway | 2013 |
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Animals, Inbred Strains; Azoxymethane; Cell Transformation, Neoplastic; Chemokines, CXC; Colitis; Colonic Neoplasms; Dermatitis, Contact; Dextran Sulfate; Gene Expression; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Papilloma; Peroxidase; Precancerous Conditions; Receptors, Interleukin-8B; Skin Neoplasms; Statistics, Nonparametric; Tetradecanoylphorbol Acetate; Tumor Burden | 2012 |
Deletion of functional gastrin gene markedly increases colon carcinogenesis in response to azoxymethane in mice.
Topics: Animals; Azoxymethane; Colonic Neoplasms; Female; Gastrins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Precancerous Conditions | 2002 |
Molecular changes in the early stage of colon carcinogenesis in rats treated with azoxymethane.
Topics: Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Cyclooxygenase 2; Genes, ras; In Situ Nick-End Labeling; Intestinal Mucosa; Isoenzymes; Male; Nucleolus Organizer Region; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-myc; Rats; Rats, Inbred F344; RNA, Messenger | 2002 |
The combination of 1alpha,25(OH2)-vitamin D3, calcium and acetylsalicylic acid affects azoxymethane-induced aberrant crypt foci and colorectal tumours in rats.
Topics: Animals; Aspirin; Azoxymethane; Body Weight; Calcitriol; Calcium; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Therapy, Combination; Eating; Male; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344 | 2002 |
Dietary inulin suppresses azoxymethane-induced preneoplastic aberrant crypt foci in mature Fisher 344 rats.
Topics: Age Factors; Animals; Azoxymethane; Carcinogens; Cecum; Colon; Colonic Neoplasms; Dietary Fiber; Disease Models, Animal; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Inulin; Male; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344 | 2002 |
Dietary inulin suppresses azoxymethane-induced aberrant crypt foci and colon tumors at the promotion stage in young Fisher 344 rats.
Topics: Age Factors; Animals; Azoxymethane; Carcinogens; Cecum; Colon; Colonic Neoplasms; Diarrhea; Dietary Fiber; Disease Models, Animal; Hydrogen-Ion Concentration; Intestinal Neoplasms; Intestine, Small; Inulin; Male; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344; Time Factors | 2002 |
Chemoprevention of precursors to colon cancer by dehydroepiandrosterone (DHEA).
Topics: Adjuvants, Immunologic; Animals; Azoxymethane; beta Catenin; Carcinogens; Chemoprevention; Colonic Neoplasms; Cytoskeletal Proteins; Dehydroepiandrosterone; Diet; Female; Immunoenzyme Techniques; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Precancerous Conditions; Trans-Activators | 2002 |
Correlation between electron-donating ability of a series of 3-nitroflavones and their efficacy to inhibit the onset and progression of aberrant crypt foci in the rat colon.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colonic Neoplasms; Flavonoids; Nitro Compounds; Precancerous Conditions; Rats; Rats, Inbred F344; Reducing Agents; Structure-Activity Relationship | 2002 |
Effects of long-term administration of sulindac on APC mRNA and apoptosis in colons of rats treated with azoxymethane.
Topics: Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Azoxymethane; Colon; Colonic Neoplasms; Cyclooxygenase Inhibitors; In Situ Nick-End Labeling; Intestinal Mucosa; Male; Nucleolus Organizer Region; Precancerous Conditions; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulindac | 2002 |
Preliminary analysis of azoxymethane induced colon tumors in inbred mice commonly used as transgenic/knockout progenitors.
Topics: Animals; Azoxymethane; Colonic Neoplasms; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C57BL; Precancerous Conditions; Species Specificity | 2003 |
Simple sugars modulate the development of aberrant crypt foci in rat colon during post-initiation.
Topics: Animals; Azoxymethane; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Dextrins; Diet; Dietary Sucrose; Male; Malondialdehyde; Oxidation-Reduction; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344; Starch | 2002 |
Chemopreventive effect of farnesol and lanosterol on colon carcinogenesis.
Topics: Animals; Azoxymethane; Cholesterol; Colonic Neoplasms; Farnesol; Lanosterol; Lipoproteins, HDL; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 2002 |
Deguelin suppresses the formation of carcinogen-induced aberrant crypt foci in the colon of CF-1 mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; beta-N-Acetylhexosaminidases; Colon; Colonic Neoplasms; Female; Intestinal Mucosa; Mice; Molecular Structure; Piroxicam; Precancerous Conditions; Rotenone | 2003 |
Direct measure of insulin sensitivity with the hyperinsulinemic-euglycemic clamp and surrogate measures of insulin sensitivity with the oral glucose tolerance test: correlations with aberrant crypt foci promotion in rats.
Topics: Animals; Azoxymethane; Colorectal Neoplasms; Dietary Fats; Glucose Clamp Technique; Glucose Tolerance Test; Hyperinsulinism; Insulin; Insulin Resistance; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 2003 |
Effects of sphingomyelin on aberrant colonic crypt foci development, colon crypt cell proliferation and immune function in an aging rat tumor model.
Topics: Aging; Animals; Azoxymethane; Body Weight; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Hemocyanins; Hypersensitivity, Delayed; Immunity; Immunoglobulin G; Killer Cells, Natural; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Sphingomyelins; Spleen | 2003 |
Identification of mucin-depleted foci in the unsectioned colon of azoxymethane-treated rats: correlation with carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Male; Mucins; Precancerous Conditions; Probiotics; Rats; Rats, Inbred F344 | 2003 |
Tomato and garlic can modulate azoxymethane-induced colon carcinogenesis in rats.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogenicity Tests; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Disease Models, Animal; Garlic; Glutathione Transferase; Injections, Subcutaneous; Lipid Peroxidation; Onions; Phytotherapy; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Solanum lycopersicum | 2003 |
Tea can protect against aberrant crypt foci formation during azoxymethane induced rat colon carcinogenesis.
Topics: Administration, Oral; Animals; Antioxidants; Azoxymethane; Biological Assay; Carcinogens; Colonic Neoplasms; Flavonoids; Glutathione Peroxidase; Glutathione Transferase; Lipid Peroxidation; Male; Neoplasms, Experimental; Phenols; Polyphenols; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Tea; Time Factors | 2003 |
Whey proteins protect more than red meat against azoxymethane induced ACF in Wistar rats.
Topics: Animals; Azoxymethane; Colonic Neoplasms; Diet; Heme; Meat; Milk Proteins; Precancerous Conditions; Rats; Rats, Wistar; Whey Proteins | 2003 |
The effects of parathyroid hormone fragments on bone formation and their lack of effects on the initiation of colon carcinogenesis in rats as indicated by preneoplastic aberrant crypt formation.
Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Osteogenesis; Parathyroid Hormone; Peptide Fragments; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 2003 |
Energy restriction reduces the number of advanced aberrant crypt foci and attenuates the expression of colonic transforming growth factor beta and cyclooxygenase isoforms in Zucker obese (fa/fa) rats.
Topics: Animals; Azoxymethane; Blood Glucose; Body Weight; Caloric Restriction; Carcinogens; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Eating; Female; Insulin; Isoenzymes; Lactic Acid; Membrane Proteins; Obesity; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Zucker; RNA, Messenger; Transforming Growth Factor beta; Triglycerides | 2003 |
Mucin-depleted foci (MDF) in the colon of rats treated with azoxymethane (AOM) are useful biomarkers for colon carcinogenesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Biomarkers, Tumor; Body Weight; Carcinogens; Cholic Acid; Colon; Colonic Neoplasms; Male; Mucins; Piroxicam; Precancerous Conditions; Rats; Rats, Inbred F344 | 2004 |
Effects of high amylose maize starch and Clostridium butyricum on metabolism in colonic microbiota and formation of azoxymethane-induced aberrant crypt foci in the rat colon.
Topics: Amylose; Animals; Azoxymethane; Body Weight; Butyrates; Carcinogens; Clostridium; Colon; Colonic Neoplasms; Dietary Fiber; Fatty Acids; Fermentation; Glucuronidase; Lactates; Male; Organ Size; Precancerous Conditions; Probiotics; Rats; Rats, Inbred F344; Spores, Bacterial; Starch; Succinates; Zea mays | 2003 |
Enhancement of development of azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice.
Topics: Animals; Azoxymethane; Blood Glucose; Body Weight; Carcinogens; Colonic Neoplasms; Diabetes Mellitus, Experimental; Heterozygote; Homozygote; Hyperinsulinism; Immunoblotting; Insulin; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Precancerous Conditions; Receptor, IGF Type 1; Receptors, Cell Surface; Receptors, Leptin | 2004 |
Interaction of conjugated linoleic acid, sphingomyelin, and butyrate on formation of colonic aberrant crypt foci and immune functions in rats.
Topics: Animals; Azoxymethane; Butyrates; Carcinogens; Colon; Colonic Neoplasms; Drug Interactions; Immune System; Intestinal Mucosa; Killer Cells, Natural; Linoleic Acids, Conjugated; Lipids; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Sphingomyelins | 2004 |
Leptin reduces the development of the initial precancerous lesions induced by azoxymethane in the rat colonic mucosa.
Topics: Animals; Azoxymethane; Carcinogens; Cell Division; Colonic Neoplasms; Infusion Pumps; Injections; Intestinal Mucosa; Leptin; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Recombinant Proteins | 2004 |
Intestinal expression of mutant and wild-type progastrin significantly increases colon carcinogenesis in response to azoxymethane in transgenic mice.
Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Female; Gastrins; Humans; Male; Mice; Mice, Transgenic; Polymerase Chain Reaction; Precancerous Conditions; Protein Precursors; Radioimmunoassay | 2004 |
The modifying effect of Peucedanum japonicum, a herb in the Ryukyu Islands, on azoxymethane-induced colon preneoplastic lesions in male F344 rats.
Topics: Animals; Antioxidants; Apiaceae; Azoxymethane; beta Catenin; Colonic Neoplasms; Cytoskeletal Proteins; Lipid Peroxidation; Male; Plant Extracts; Precancerous Conditions; Rats; Rats, Inbred F344; Trans-Activators | 2004 |
Modulatory influence of garlic and tomato on cyclooxygenase-2 activity, cell proliferation and apoptosis during azoxymethane induced colon carcinogenesis in rat.
Topics: Animals; Apoptosis; Azoxymethane; Cell Division; Colonic Neoplasms; Cyclooxygenase 2; Garlic; Isoenzymes; Male; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Solanum lycopersicum | 2004 |
Preventive effects of extract of leaves of ginkgo (Ginkgo biloba) and its component bilobalide on azoxymethane-induced colonic aberrant crypt foci in rats.
Topics: Administration, Oral; Animals; Azoxymethane; Carcinogens; Chemoprevention; Colonic Neoplasms; Cyclopentanes; Cytochrome P-450 Enzyme System; Diet; Diterpenes; Furans; Ginkgo biloba; Ginkgolides; Glutathione Transferase; Immunohistochemistry; Male; Phytotherapy; Plant Extracts; Plant Leaves; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344 | 2004 |
[Beta-catenin-accumulated crypt--a novel pre-cancerous condition in rat colorectal neoplasm model].
Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Colorectal Neoplasms; Cytoskeletal Proteins; Precancerous Conditions; Rats; Rats, Inbred F344; Trans-Activators | 2004 |
Diosgenin, a steroid saponin of Trigonella foenum graecum (Fenugreek), inhibits azoxymethane-induced aberrant crypt foci formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells.
Topics: Animals; Apoptosis; Azoxymethane; Cell Division; Colonic Neoplasms; Diosgenin; Disease Models, Animal; History, Early Modern 1451-1600; HT29 Cells; Humans; Intestinal Mucosa; Male; Plant Extracts; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344; Reference Values; Saponins; Sensitivity and Specificity; Trigonella; Tumor Cells, Cultured | 2004 |
Tumor suppressor functions for the Cdk inhibitor p21 in the mouse colon.
Topics: Animals; Apoptosis; Azoxymethane; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Female; In Situ Nick-End Labeling; Mice; Precancerous Conditions | 2004 |
Sequential observations on the occurrence of preneoplastic and neoplastic lesions in mouse colon treated with azoxymethane and dextran sodium sulfate.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Immunoenzyme Techniques; Incidence; Injections, Intraperitoneal; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; Precancerous Conditions; Tyrosine | 2004 |
Dietary iron promotes azoxymethane-induced colon tumors in mice.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogens; Cell Division; Colonic Neoplasms; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; In Situ Nick-End Labeling; Iron, Dietary; Mice; Oxidative Stress; Precancerous Conditions; Random Allocation; Time Factors | 2004 |
Low doses of beta-carotene and lutein inhibit AOM-induced rat colonic ACF formation but high doses augment ACF incidence.
Topics: Animals; Antioxidants; Azoxymethane; beta Carotene; Carcinogens; Chemoprevention; Colonic Neoplasms; Diet; Dose-Response Relationship, Drug; Lutein; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 2005 |
Leptin reduces the development of the initial precancerous lesions induced by azoxymethane in the rat colonic mucosa.
Topics: Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colonic Neoplasms; Intestinal Mucosa; Leptin; Obesity; Precancerous Conditions; Rats; Rats, Zucker | 2004 |
Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogens; Carrier Proteins; Cell Cycle; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Folate Receptors, GPI-Anchored; Gene Expression Profiling; Gene Silencing; Genetic Predisposition to Disease; Kidney; Male; Membrane Transport Modulators; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Precancerous Conditions; Receptors, Cell Surface; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylhomocysteine; S-Adenosylmethionine | 2005 |
Inhibitory effects of feeding with carrots or (-)-falcarinol on development of azoxymethane-induced preneoplastic lesions in the rat colon.
Topics: Alkynes; Animals; Azoxymethane; Colonic Neoplasms; Daucus carota; Diet; Diynes; Fatty Alcohols; Male; Plant Extracts; Precancerous Conditions; Rats | 2005 |
Increased microvascular blood content is an early event in colon carcinogenesis.
Topics: Adenoma; Animals; Azoxymethane; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Disease Models, Animal; Disease Progression; Hemoglobins; Humans; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Microcirculation; Optics and Photonics; Pilot Projects; Precancerous Conditions; Rats; Rats, Inbred F344; Scattering, Radiation | 2005 |
Abdominal obesity, insulin resistance, and colon carcinogenesis are increased in mutant mice lacking gastrin gene expression.
Topics: Animals; Azoxymethane; Body Weight; Carcinogens; Colonic Neoplasms; Gastrins; Gene Expression; Ghrelin; Glucose; Hyperinsulinism; Insulin; Insulin Resistance; Leptin; Magnetic Resonance Imaging; Male; Mice; Mice, Knockout; Obesity; Peptide Hormones; Precancerous Conditions; Radioimmunoassay; Thinness | 2005 |
Polyethylene glycol reduces inflammation and aberrant crypt foci in carcinogen-initiated rats.
Topics: Administration, Oral; Animals; Azoxymethane; Caco-2 Cells; Carcinogens; Colon; Colonic Neoplasms; Humans; Inflammation; Male; Permeability; Polyethylene Glycols; Precancerous Conditions; Rats; Rats, Inbred F344; Solvents | 2005 |
Dietary supplement of isohumulones inhibits the formation of aberrant crypt foci with a concomitant decrease in prostaglandin E2 level in rat colon.
Topics: Animals; Azoxymethane; Beer; Carcinogens; Cell Line; Colon; Colonic Neoplasms; Cyclopentanes; Dietary Supplements; Dinoprostone; Interferon-gamma; Intestinal Mucosa; Ionophores; Lipopolysaccharides; Macrophages; Male; Mice; Precancerous Conditions; Rats; Rats, Inbred F344 | 2005 |
Senna and the formation of aberrant crypt foci and tumors in rats treated with azoxymethane.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Azoxymethane; Cathartics; Colonic Neoplasms; Male; Phytotherapy; Precancerous Conditions; Rats; Rats, Wistar; Senna Extract; Senna Plant | 2005 |
Lack of enhancing effects of degraded lambda-carrageenan on the development of beta-catenin-accumulated crypts in male DBA/2J mice initiated with azoxymethane.
Topics: Animals; Azoxymethane; beta Catenin; Biomarkers, Tumor; Carcinogens; Carrageenan; Intestinal Mucosa; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Precancerous Conditions; Species Specificity | 2006 |
Identification of flat dysplastic aberrant crypt foci in the colon of azoxymethane-treated A/J mice.
Topics: Animals; Azoxymethane; beta Catenin; Carcinogens; Cell Nucleus; Colonic Neoplasms; Cyclin D1; Female; Hyperplasia; Male; Mice; Mice, Inbred A; Precancerous Conditions | 2006 |
Suppressive effect of an inducible nitric oxide inhibitor, ONO-1714, on AOM-induced rat colon carcinogenesis.
Topics: Amidines; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Heterocyclic Compounds, 2-Ring; Male; Nitric Oxide Synthase Type II; Precancerous Conditions; Rats; Rats, Inbred F344 | 2006 |
Dietary artepillin C suppresses the formation of aberrant crypt foci induced by azoxymethane in mouse colon.
Topics: Animals; Antineoplastic Agents; Antioxidants; Azoxymethane; Carcinogens; Colonic Neoplasms; Diet; Dose-Response Relationship, Drug; Glutathione Transferase; Intestinal Mucosa; Liver; Male; Mice; NAD(P)H Dehydrogenase (Quinone); Phenylpropionates; Precancerous Conditions; Propolis; Response Elements; Up-Regulation | 2006 |
Mitogenic effects of both amidated and glycine-extended gastrin-releasing peptide in defunctioned and azoxymethane-treated rat colon in vivo.
Topics: Animals; Azoxymethane; Cell Proliferation; Colon; Colonic Neoplasms; Gastrin-Releasing Peptide; Glycine; Male; Mitosis; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Rectum; Species Specificity; Time Factors | 2006 |
Effect of dried plums on colon cancer risk factors in rats.
Topics: Animals; Azoxymethane; Bile Acids and Salts; Cecum; Colonic Neoplasms; Dose-Response Relationship, Drug; Feces; Glucuronidase; Male; Nitroreductases; Oxidoreductases; Precancerous Conditions; Prunus; Random Allocation; Rats; Rats, Wistar; Risk Factors | 2005 |
Modifying effect of dietary sesaminol glucosides on the formation of azoxymethane-induced premalignant lesions of rat colon.
Topics: Animals; Azoxymethane; Colon; Colonic Neoplasms; Dietary Supplements; Dioxoles; Fatty Acid-Binding Proteins; Furans; Gene Expression; Glucosides; Intestinal Mucosa; Male; Molecular Structure; Precancerous Conditions; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesamum; Triglycerides | 2007 |
Preventive effects of chrysin on the development of azoxymethane-induced colonic aberrant crypt foci in rats.
Topics: Administration, Oral; Animals; Apoptosis; Azoxymethane; Carcinogens; Chemoprevention; Colonic Neoplasms; Diet; Flavonoids; Injections, Subcutaneous; Male; Mitosis; Precancerous Conditions; Rats; Rats, Inbred F344 | 2006 |
Polyethylene glycol, unique among laxatives, suppresses aberrant crypt foci, by elimination of cells.
Topics: Animals; Azoxymethane; Carcinogens; Cathartics; Colonic Neoplasms; Feces; Polyethylene Glycols; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344; Toxicity Tests, Acute | 2006 |
Red palm oil suppresses the formation of azoxymethane (AOM) induced aberrant crypt foci (ACF) in Fisher 344 male rats.
Topics: Animals; Azoxymethane; Carotenoids; Colonic Neoplasms; Eating; Glutathione Transferase; Liver; Male; Palm Oil; Plant Oils; Precancerous Conditions; Rats; Rats, Inbred F344; Soybean Oil; Vitamin E; Weight Gain | 2006 |
Methionine restriction inhibits colon carcinogenesis.
Topics: Animals; Azoxymethane; Biological Assay; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; Methionine; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344 | 2006 |
Effect of dietary apigenin on colonic ornithine decarboxylase activity, aberrant crypt foci formation, and tumorigenesis in different experimental models.
Topics: Animals; Apigenin; Azoxymethane; Caco-2 Cells; Carcinogens; Colon; Colonic Neoplasms; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Precancerous Conditions; Random Allocation | 2006 |
Catalpa seed oil rich in 9t,11t,13c-conjugated linolenic acid suppresses the development of colonic aberrant crypt foci induced by azoxymethane in rats.
Topics: Animals; Azoxymethane; Bignoniaceae; Body Weight; Cholesterol; Colon; Colonic Neoplasms; Cyclooxygenase 2; Immunohistochemistry; Intestinal Mucosa; Linolenic Acids; Lipids; Liver; Male; Organ Size; Plant Oils; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Seeds; Triglycerides | 2006 |
Carbohydrate digestibility predicts colon carcinogenesis in azoxymethane-treated rats.
Topics: Animals; Azoxymethane; Carcinogens; Cecum; Colonic Neoplasms; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Digestion; Disease Models, Animal; Fructose; Hydrogen-Ion Concentration; Inulin; Lipid Metabolism; Male; Oligosaccharides; Organ Size; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344; Solubility; Triglycerides | 2006 |
Flax seed oil and flax seed meal reduce the formation of aberrant crypt foci (ACF) in azoxymethane-induced colon cancer in Fisher 344 male rats.
Topics: Animals; Azoxymethane; Cecum; Colon; Colonic Neoplasms; Dietary Fats, Unsaturated; Dose-Response Relationship, Drug; Glutathione Transferase; Intestinal Mucosa; Linseed Oil; Liver; Male; Oils; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344; Soybean Oil | 2007 |
Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats.
Topics: Animals; Azoxymethane; beta Catenin; Body Weight; Cell Proliferation; Colorectal Neoplasms; Dietary Supplements; Male; Precancerous Conditions; Quercetin; Rats; Rats, Inbred F344; Rutin | 2006 |
Diet supplemented with citrus unshiu segment membrane suppresses chemically induced colonic preneoplastic lesions and fatty liver in male db/db mice.
Topics: Animals; Azoxymethane; Carcinogens; Cholesterol; Colon; Colonic Neoplasms; Diet; Dietary Supplements; Fatty Liver; Insulin; Leptin; Liver; Male; Mice; Mice, Inbred Strains; Plant Extracts; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Triglycerides | 2007 |
Deoxycholic acid promotes the growth of colonic aberrant crypt foci.
Topics: Animals; Azoxymethane; beta Catenin; Cadherins; Carcinogens; Cell Nucleus; Colon; Colonic Neoplasms; Deoxycholic Acid; Detergents; Hyperplasia; Male; Mice; Mice, Inbred AKR; Precancerous Conditions; Protein Transport | 2007 |
Enhanced estrogenic responses and sensitivity to azoxymethane following dietary soy isoflavone supplementation in older female rats.
Topics: Aging; Animals; Azoxymethane; Colon; Colonic Neoplasms; Dietary Supplements; Estradiol; Estrogen Receptor beta; Female; Glycine max; Isoflavones; Precancerous Conditions; Rats; Rats, Inbred F344 | 2007 |
Mixed tocopherols inhibit azoxymethane-induced aberrant crypt foci in rats.
Topics: alpha-Tocopherol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Colon; Colonic Neoplasms; Cyclooxygenase Inhibitors; gamma-Tocopherol; Male; Mice; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344; Vitamins | 2006 |
Long-term feeding of various fat diets modulates azoxymethane-induced colon carcinogenesis through Wnt/beta-catenin signaling in rats.
Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Corn Oil; Cyclin D; Cyclins; Dietary Fats; Disease Models, Animal; Fats; Fish Oils; Male; Olive Oil; Plant Oils; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Wnt Proteins | 2007 |
Chitosan prevents the development of AOM-induced aberrant crypt foci in mice and suppressed the proliferation of AGS cells by inhibiting DNA synthesis.
Topics: Animals; Azoxymethane; Blotting, Western; Carcinogens; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chitosan; Colonic Neoplasms; DNA Replication; Flow Cytometry; Humans; Jurkat Cells; Male; Mice; Mice, Inbred ICR; Molecular Weight; Precancerous Conditions; Stomach Neoplasms; Time Factors; Urinary Bladder Neoplasms | 2007 |
Study of superoxide dismutase's expression in the colon produced by azoxymethane and inositol hexaphosfate's paper, in mice.
Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Male; Phytic Acid; Precancerous Conditions; Rats; Rats, Wistar; Superoxide Dismutase | 2006 |
Selected fruits reduce azoxymethane (AOM)-induced aberrant crypt foci (ACF) in Fisher 344 male rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Blueberry Plants; Colonic Neoplasms; Fruit; Glutathione Transferase; Liver; Lythraceae; Male; Plant Extracts; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344 | 2007 |
Zapotin, a phytochemical present in a Mexican fruit, prevents colon carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogens; Cell Division; Cell Line, Tumor; Colon; Colonic Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Flavones; Flow Cytometry; HT29 Cells; Humans; Manilkara; Mice; Mice, Inbred Strains; Precancerous Conditions; Time Factors | 2007 |
Citrus auraptene suppresses azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db mice.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Carcinogens; Cell Division; Citrus; Colonic Neoplasms; Coumarins; Diet; Female; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phenotype; Precancerous Conditions; Random Allocation | 2007 |
Reovirus decreases azoxymethane-induced aberrant crypt foci and colon cancer in a rodent model.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; CD8-Positive T-Lymphocytes; Colonic Neoplasms; Female; Lymphocytes; Male; Orthoreovirus; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 2007 |
Colon cancer chemoprevention by a novel NO chimera that shows anti-inflammatory and antiproliferative activity in vitro and in vivo.
Topics: Animals; Apoptosis; Azoxymethane; Cell Count; Cell Line, Tumor; Cell Proliferation; Chemoprevention; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p27; Disulfides; DNA Damage; Enzyme Induction; Flow Cytometry; Humans; Inflammation; Male; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Poly(ADP-ribose) Polymerases; Precancerous Conditions; Rats; Rats, Inbred F344 | 2007 |
S-adenosyl L-methionine inhibits azoxymethane-induced colonic aberrant crypt foci in F344 rats and suppresses human colon cancer Caco-2 cell growth in 3D culture.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Blotting, Western; Caco-2 Cells; Cell Culture Techniques; Cells, Cultured; Collagen; Colon; Colonic Neoplasms; Colonic Polyps; Cyclooxygenase 2; Drug Combinations; Humans; Laminin; Lipopolysaccharides; Male; Maximum Tolerated Dose; Precancerous Conditions; Proteoglycans; Rats; Rats, Inbred F344; S-Adenosylmethionine; Spheroids, Cellular | 2008 |
Strain-specific homeostatic responses during early stages of Azoxymethane-induced colon tumorigenesis in mice.
Topics: Animals; Apoptosis; Azoxymethane; Blotting, Western; Carcinogens; Colon; Colonic Neoplasms; Epithelial Cells; In Situ Nick-End Labeling; Intestinal Mucosa; Male; Mice; Mice, Inbred A; Mice, Inbred AKR; Precancerous Conditions; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon.
Topics: Amidohydrolases; Animals; Azoxymethane; Cannabinoid Receptor Modulators; Caspase 3; Caspase 9; Colon; Colonic Neoplasms; Endocannabinoids; Mass Spectrometry; Mice; Precancerous Conditions; Receptors, Cannabinoid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
Green tea polyphenols inhibit colorectal aberrant crypt foci (ACF) formation and prevent oncogenic changes in dysplastic ACF in azoxymethane-treated F344 rats.
Topics: Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Flavonoids; Phenols; Polyphenols; Precancerous Conditions; Rats; Rats, Inbred F344; Tea | 2008 |
9trans,11trans conjugated linoleic acid inhibits the development of azoxymethane-induced colonic aberrant crypt foci in rats.
Topics: Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Cell Division; Colon; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Immunohistochemistry; Intestinal Mucosa; Linoleic Acids, Conjugated; Lipids; Male; PPAR gamma; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344 | 2007 |
Tissue zinc levels in precancerous tissue in the gastrointestinal tract of azoxymethane (AOM)-treated rats.
Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Gastrointestinal Tract; Precancerous Conditions; Rats; Rats, Wistar; Superoxide Dismutase; Zinc | 2008 |
Lack of interleukin-4 receptor alpha chain-dependent signalling promotes azoxymethane-induced colorectal aberrant crypt focus formation in Balb/c mice.
Topics: Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colorectal Neoplasms; Disease Models, Animal; Female; Interleukin-13; Interleukin-4; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Mice, Knockout; Precancerous Conditions; Receptors, Cell Surface; Signal Transduction; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2008 |
Oncogenic K-ras promotes early carcinogenesis in the mouse proximal colon.
Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Genes, ras; Immunoblotting; Immunohistochemistry; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Precancerous Conditions; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Susceptibility of Snark-deficient mice to azoxymethane-induced colorectal tumorigenesis and the formation of aberrant crypt foci.
Topics: Animals; Azoxymethane; Body Weight; Carcinogens; Colorectal Neoplasms; Female; Gastrointestinal Tract; Genetic Predisposition to Disease; Mice; Mice, Mutant Strains; Obesity; Precancerous Conditions; Protein Serine-Threonine Kinases; Risk Factors | 2008 |
Chemoprevention of colon carcinogenesis by oleanolic acid and its analog in male F344 rats and modulation of COX-2 and apoptosis in human colon HT-29 cancer cells.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; HT29 Cells; Humans; Macrophages; Male; Mice; Nitric Oxide Synthase Type II; Oleanolic Acid; Precancerous Conditions; Rats; Rats, Inbred F344 | 2008 |
Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model.
Topics: Animals; Azoxymethane; CCAAT-Enhancer-Binding Protein-beta; Colonic Neoplasms; Cyclin D; Cyclins; Disease Progression; ErbB Receptors; Gefitinib; Male; Precancerous Conditions; Quinazolines; Rats; Rats, Inbred F344; STAT3 Transcription Factor; Transcription Factor AP-1 | 2008 |
Detection of early neoplastic changes in experimentally induced colorectal cancer using scanning electron microscopy and cell kinetic studies.
Topics: Adenoma; Animals; Azoxymethane; Cell Division; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; Microscopy, Electron, Scanning; Precancerous Conditions; Rats; Rats, Inbred Strains; Rectal Neoplasms | 1984 |
Morphogenesis of colonic carcinoma. Ultrastructural studies of azoxymethane-induced early lesions in colon epithelium of Fischer 344 rats.
Topics: Animals; Azo Compounds; Azoxymethane; Colon; Colonic Neoplasms; Intestinal Mucosa; Models, Biological; Precancerous Conditions; Rats; Rats, Inbred F344 | 1982 |
Colon epithelium. II. In vivo studies of colon carcinogenesis. Light microscopic, histochemical, and ultrastructural studies of histogenesis of azoxymethane-induced colon carcinomas in Fischer 344 rats.
Topics: Animals; Azo Compounds; Azoxymethane; Carcinoma; Colonic Neoplasms; Epithelium; Intestinal Mucosa; Male; Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Inbred F344 | 1981 |
Characterisation of aberrant crypt foci in carcinogen-treated rats: association with intestinal carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Dimethylhydrazines; Female; Intestinal Mucosa; Mucins; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1995 |
Chemoprevention of azoxymethane-induced intestinal carcinogenesis by a novel synthesized retinoidal butenolide, 5-hydroxy-4-(2-phenyl-(E)-ethenyl)-2(5H)-furanone, in rats.
Topics: 4-Butyrolactone; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Azoxymethane; Biomarkers, Tumor; Bromodeoxyuridine; Colon; Dose-Response Relationship, Drug; Epithelium; Intestinal Neoplasms; Male; Ornithine Decarboxylase; Precancerous Conditions; Rats; Rats, Inbred F344; Retinoids | 1995 |
Inhibitory effect of Bifidobacterium longum cultures on the azoxymethane-induced aberrant crypt foci formation and fecal bacterial beta-glucuronidase.
Topics: Animals; Azoxymethane; Bacteria; Bifidobacterium; Colonic Neoplasms; Feces; Glucuronidase; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1994 |
Inhibition of aberrant crypt growth by non-steroidal anti-inflammatory agents and differentiation agents in the rat colon.
Topics: Acetaminophen; Adenoma; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Azoxymethane; Colonic Neoplasms; Drug Screening Assays, Antitumor; Fenretinide; Ibuprofen; Isotretinoin; Male; Piroxicam; Precancerous Conditions; Rats; Rats, Inbred F344 | 1995 |
Effect of beta-carotene and wheat bran fiber on colonic aberrant crypt and tumor formation in rats exposed to azoxymethane and high dietary fat.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; beta Carotene; Body Weight; Carotenoids; Cocarcinogenesis; Colonic Neoplasms; Dietary Fats; Dietary Fiber; Dose-Response Relationship, Drug; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Triticum | 1995 |
Further investigation of the effect of cholic acid on the induction, growth characteristics and stability of aberrant crypt foci in rat colon.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Cell Division; Cholic Acid; Cholic Acids; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Mitosis; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1995 |
Modifying effects of naturally occurring products on the development of colonic aberrant crypt foci induced by azoxymethane in F344 rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Biogenic Polyamines; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; Nucleolus Organizer Region; Oleanolic Acid; Ornithine Decarboxylase; Precancerous Conditions; Rats; Rats, Inbred F344; Sesquiterpenes | 1995 |
Increased cell proliferation of azoxymethane-induced aberrant crypt foci of rat colon.
Topics: Animals; Azoxymethane; Bromodeoxyuridine; Cell Division; Colon; Colonic Neoplasms; Epithelium; Kinetics; Male; Mitotic Index; Nuclear Proteins; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344 | 1994 |
Resistance of aberrant crypt foci to apoptosis induced by azoxymethane in rats chronically fed cholic acid.
Topics: Animals; Apoptosis; Azoxymethane; Bromodeoxyuridine; Cholic Acid; Cholic Acids; Colonic Neoplasms; DNA; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1994 |
Suppression of azoxymethane-induced rat colon aberrant crypt foci by dietary protocatechuic acid.
Topics: Animals; Anticarcinogenic Agents; Antigens, Nuclear; Azoxymethane; Colon; Colonic Neoplasms; Diet; Epithelium; Hydroxybenzoates; Intestinal Mucosa; Male; Nuclear Proteins; Nucleolus Organizer Region; Ornithine Decarboxylase; Precancerous Conditions; Rats; Rats, Inbred F344; Silver Staining | 1994 |
Asbestos induces aberrant crypt foci in the colon of rats.
Topics: Animals; Asbestos, Crocidolite; Asbestos, Serpentine; Azoxymethane; Carcinogenicity Tests; Colonic Neoplasms; Female; Mice; Precancerous Conditions; Rats; Rats, Inbred F344 | 1993 |
Inhibitory effect of caffeic acid esters on azoxymethane-induced biochemical changes and aberrant crypt foci formation in rat colon.
Topics: Animals; Anticarcinogenic Agents; Arachidonic Acid; Azoxymethane; Caffeic Acids; Colon; Colonic Neoplasms; Male; Ornithine Decarboxylase; Precancerous Conditions; Protein-Tyrosine Kinases; Rats; Rats, Inbred F344 | 1993 |
Ability of aberrant crypt foci characteristics to predict colonic tumor incidence in rats fed cholic acid.
Topics: Animals; Azoxymethane; Carcinogens; Cholic Acid; Cholic Acids; Colon; Colonic Neoplasms; Diet; Incidence; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1993 |
Reduction of aberrant crypt foci induced in rat colon with azoxymethane or methylnitrosourea by feeding cholic acid.
Topics: Analysis of Variance; Animals; Azoxymethane; Body Weight; Cell Division; Cholic Acid; Cholic Acids; Colonic Neoplasms; Intestinal Mucosa; Male; Methylnitrosourea; Precancerous Conditions; Random Allocation; Rats; Rats, Sprague-Dawley | 1993 |
Effect of restricted caloric intake on the development of the azoxymethane-induced glutathione S-transferase placental form positive hepatocellular foci in male F344 rats.
Topics: Animals; Azoxymethane; Dietary Fats; Energy Intake; Glutathione Transferase; Isoenzymes; Liver Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1993 |
Effects of all-trans retinoic acid as a potential chemopreventive agent on the formation of azoxymethane-induced aberrant crypt foci: differential expression of c-myc and c-fos MRNA and protein.
Topics: Animals; Azoxymethane; Body Weight; Colon; Colonic Neoplasms; Genes, fos; Genes, myc; Male; Precancerous Conditions; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tretinoin | 1993 |
Initiation and promotion of colonic aberrant crypt foci in rats by 5-hydroxymethyl-2-furaldehyde in thermolyzed sucrose.
Topics: Animals; Azoxymethane; Colon; Colonic Neoplasms; Female; Furaldehyde; Hot Temperature; Precancerous Conditions; Rats; Rats, Inbred F344; Sucrose | 1993 |
Sucrose enhancement of the early steps of colon carcinogenesis in mice.
Topics: Animals; Azoxymethane; Cell Division; Cocarcinogenesis; Colonic Neoplasms; Female; Fructose; Glucose; Mice; Mice, Inbred C57BL; Mitosis; Precancerous Conditions; Species Specificity; Sucrose | 1993 |
Two types of putative preneoplastic lesions identified by hexosaminidase activity in whole-mounts of colons from F344 rats treated with carcinogen.
Topics: Animals; Azoxymethane; Carcinogens; Clinical Enzyme Tests; Colon; Colonic Neoplasms; Hexosaminidases; Injections, Subcutaneous; Male; Microvilli; Phytic Acid; Precancerous Conditions; Rats; Rats, Inbred F344 | 1993 |
Effect of fish oil on the development of AOM-induced glutathione S-transferase placental form positive hepatocellular foci in male F344 rats.
Topics: Animals; Azoxymethane; Carcinogens; Carcinoma, Hepatocellular; Fish Oils; Glutathione Transferase; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1995 |
Suppression of azoxymethane-induced aberrant crypt foci in rat colon by nimesulide, a selective inhibitor of cyclooxygenase 2.
Topics: Animals; Azoxymethane; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Intestinal Mucosa; Isoenzymes; Male; Neoplasms, Experimental; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Sulfonamides | 1996 |
Unexpected antagonistic action of 3,2'-dimethyl-4-aminobiphenyl on aberrant crypt induction by 1,2-dimethylhydrazine or azoxymethane in rat colon.
Topics: 1,2-Dimethylhydrazine; Aminobiphenyl Compounds; Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Diet; Dimethylhydrazines; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Rats, Inbred Lew | 1995 |
The influence of high and low molecular weight chitosan on colonic cell proliferation and aberrant crypt foci development in CF1 mice.
Topics: Animals; Azoxymethane; Carcinogens; Cell Division; Chitin; Chitosan; Colon; Colonic Neoplasms; Dietary Fiber; Female; Mice; Molecular Weight; Precancerous Conditions; Random Allocation; Solubility | 1996 |
Effect of amount and types of dietary fat on intestinal bacterial 7 alpha-dehydroxylase and phosphatidylinositol-specific phospholipase C and colonic mucosal diacylglycerol kinase and PKC activities during stages of colon tumor promotion.
Topics: Animals; Azoxymethane; Bacterial Proteins; Bile Acids and Salts; Carcinogens; Cecum; Cocarcinogenesis; Colon; Colonic Neoplasms; Corn Oil; Diacylglycerol Kinase; Dietary Fats; Fish Oils; Hydroxysteroid Dehydrogenases; Intestinal Mucosa; Male; Oxidoreductases; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Phosphotransferases (Alcohol Group Acceptor); Precancerous Conditions; Protein Kinase C; Rats; Rats, Inbred F344; Steroid Hydroxylases | 1996 |
Inhibitory effects of d-limonene on the development of colonic aberrant crypt foci induced by azoxymethane in F344 rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Cyclohexenes; Drinking; Drug Screening Assays, Antitumor; Limonene; Male; Nucleolus Organizer Region; Ornithine Decarboxylase; Precancerous Conditions; Rats; Rats, Inbred F344; Terpenes | 1996 |
Piroxicam-induced regression of azoxymethane-induced aberrant crypt foci and prevention of colon cancer in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Drug Screening Assays, Antitumor; Male; Piroxicam; Precancerous Conditions; Rats; Rats, Inbred F344 | 1996 |
Dietary fiber and the chemopreventive modelation of colon carcinogenesis.
Topics: Animals; Azoxymethane; beta Carotene; Carcinogens; Carotenoids; Colon; Colonic Neoplasms; Diet; Dietary Fats; Dietary Fiber; Genes, ras; Humans; Intestinal Mucosa; Phytic Acid; Precancerous Conditions; Psyllium; Rats; Rats, Inbred F344; Risk Factors | 1996 |
Inability of low- or high-fat diet to modulate late stages of colon carcinogenesis in Sprague-Dawley rats.
Topics: Animals; Azoxymethane; Body Weight; Carcinogens; Cocarcinogenesis; Colonic Neoplasms; Dietary Fats; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1996 |
Suppressing effect of perilla oil on azoxymethane-induced foci of colonic aberrant crypts in rats.
Topics: alpha-Linolenic Acid; Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Dinoprost; Dose-Response Relationship, Drug; Eating; Fatty Acids, Omega-3; Intestinal Mucosa; Male; Nucleolus Organizer Region; Phospholipids; Plant Oils; Precancerous Conditions; Rats; Rats, Inbred F344; Silver Staining | 1996 |
Effects of the phytochemicals, curcumin and quercetin, upon azoxymethane-induced colon cancer and 7,12-dimethylbenz[a]anthracene-induced mammary cancer in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Carcinogens; Colonic Neoplasms; Curcumin; Drug Interactions; Female; Male; Mammary Neoplasms, Experimental; Plant Extracts; Precancerous Conditions; Quercetin; Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 1996 |
Suppressing effects of 6-(2,5-dichlorophenyl)-2,4-diamino-1,3,5-triazine and related synthetic compounds on azoxymethane-induced aberrant crypt foci in rat colon.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Colonic Neoplasms; Diet; Epithelium; Intestinal Mucosa; Male; Ornithine Decarboxylase; Polyamines; Precancerous Conditions; Rats; Rats, Inbred F344; Triazines | 1996 |
Growth features of aberrant crypt foci that resist modulation by cholic acid.
Topics: Analysis of Variance; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Cholic Acid; Cholic Acids; Colon; Colonic Neoplasms; Diet; Intestinal Mucosa; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1996 |
Evaluation of cyclooxygenase-2 inhibitor for potential chemopreventive properties in colon carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Screening Assays, Antitumor; Isoenzymes; Male; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Rats, Inbred Lew; Sulindac | 1996 |
Modulation of colonic aberrant crypt foci and proliferative indexes in colon and prostate glands of rats by vitamin E.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Azoxymethane; Cell Division; Colon; Colonic Neoplasms; Male; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Prostate; Rats; Rats, Inbred F344; Vitamin E | 1996 |
Bifidobacterium longum and lactulose suppress azoxymethane-induced colonic aberrant crypt foci in rats.
Topics: Animal Feed; Animals; Anticarcinogenic Agents; Azoxymethane; Bifidobacterium; Biomarkers; Carcinogens; Colon; Colonic Diseases; Colonic Neoplasms; Diarrhea; Diet; Glutathione Transferase; Hydrogen-Ion Concentration; Intestinal Mucosa; Isoenzymes; Lactulose; Liver; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1997 |
Carrageenan given as a jelly, does not initiate, but promotes the growth of aberrant crypt foci in the rat colon.
Topics: Animals; Azoxymethane; Carrageenan; Colon; Colonic Diseases; Intestinal Mucosa; Occult Blood; Precancerous Conditions; Rats; Weight Gain | 1997 |
Cooked casein promotes colon cancer in rats, may be because of mucosal abrasion.
Topics: Alkaline Phosphatase; Animals; Azoxymethane; Bile Acids and Salts; Caseins; Colonic Neoplasms; Feces; Intestinal Mucosa; Precancerous Conditions; Rats; Rats, Inbred F344 | 1997 |
Effect of soya bean saponins on azoxymethane-induced preneoplastic lesions in the colon of mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Glycine max; Male; Mice; Precancerous Conditions; Saponins | 1997 |
A xanthine oxidase inhibitor 1'-acetoxychavicol acetate inhibits azoxymethane-induced colonic aberrant crypt foci in rats.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Benzyl Alcohols; Body Weight; Cell Division; Colon; Colonic Diseases; Enzyme Inhibitors; Intestinal Mucosa; Liver; Male; Organ Size; Ornithine Decarboxylase; Polyamines; Precancerous Conditions; Rats; Rats, Inbred F344; Terpenes; Xanthine Oxidase | 1997 |
Inhibition by wheat bran cereals of the development of aberrant crypt foci and colon tumours.
Topics: Animals; Azoxymethane; Colonic Neoplasms; Dietary Fiber; Food, Formulated; Hyperplasia; Intestinal Mucosa; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1997 |
Suppression of azoxymethane-induced rat colon carcinoma development by a fish oil component, docosahexaenoic acid (DHA).
Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Docosahexaenoic Acids; Lipids; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1997 |
Chemopreventive agents-induced regression of azoxymethane-induced aberrant crypt foci with the recovery of hexosaminidase activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Azoxymethane; beta-N-Acetylhexosaminidases; Carcinogens; Colonic Neoplasms; Curcumin; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1997 |
Prevention by retinoids of azoxymethane-induced tumors and aberrant crypt foci and their modulation of cell proliferation in the colon of rats.
Topics: Alitretinoin; Animals; Anticarcinogenic Agents; Azoxymethane; Cell Division; Colonic Neoplasms; Fenretinide; Male; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Tretinoin | 1997 |
Citrus auraptene inhibits chemically induced colonic aberrant crypt foci in male F344 rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Citrus; Colonic Neoplasms; Coumarins; Glutathione Transferase; Male; NAD(P)H Dehydrogenase (Quinone); Ornithine Decarboxylase; Precancerous Conditions; Rats; Rats, Inbred F344 | 1997 |
Inhibitory effect of NS-398, a selective cyclooxygenase-2 inhibitor, on azoxymethane-induced aberrant crypt foci in colon carcinogenesis of F344 rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Carcinogens; Colon; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Immunohistochemistry; Isoenzymes; Liver; Male; Nitrobenzenes; Organ Size; Polymerase Chain Reaction; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; RNA, Messenger; Sulfonamides | 1997 |
Effect of Bifidobacterium longum and inulin on gut bacterial metabolism and carcinogen-induced aberrant crypt foci in rats.
Topics: Ammonia; Animals; Azoxymethane; Bacteria; beta-Glucosidase; Bifidobacterium; Cecum; Colonic Neoplasms; Glucuronidase; Hydrogen-Ion Concentration; Intestinal Mucosa; Inulin; Male; Precancerous Conditions; Probiotics; Rats; Rats, Sprague-Dawley | 1998 |
Chemopreventive effect of squalene on colon cancer.
Topics: Animals; Azoxymethane; Body Weight; Colonic Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Squalene; Sulindac | 1998 |
Effect of calcium on azoxymethane-induced aberrant crypt foci and cell proliferation in the colon of rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Calcium; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Eating; Male; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Risk Factors | 1998 |
Effect of dietary deoxycholic acid and cholesterol on fecal steroid concentration and its impact on the colonic crypt cell proliferation in azoxymethane-treated rats.
Topics: Animals; Azoxymethane; Bile Acids and Salts; Body Weight; Carcinogens; Cell Division; Cholesterol, Dietary; Cocarcinogenesis; Colon; Colonic Neoplasms; Deoxycholic Acid; Eating; Feces; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Steroids | 1998 |
Effect of dietary chlorogenic acid on multiple immune functions and formation of aberrant crypt foci in rats.
Topics: Animals; Antibody Formation; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Chemoprevention; Chlorogenic Acid; Colon; Colonic Neoplasms; Cytotoxicity, Immunologic; Diet; Immune Tolerance; Immunity, Cellular; Killer Cells, Natural; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1998 |
Dietary quercetin, immune functions and colonic carcinogenesis in rats.
Topics: Animals; Azoxymethane; Cell Division; Colonic Neoplasms; Female; Killer Cells, Natural; Precancerous Conditions; Quercetin; Rats; Rats, Sprague-Dawley | 1998 |
Inhibition of initiation and early stage development of aberrant crypt foci and enhanced natural killer activity in male rats administered bovine lactoferrin concomitantly with azoxymethane.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Bifidobacterium; Carcinogens; Chemoprevention; Colonic Neoplasms; Drug Administration Schedule; Killer Cells, Natural; Lactoferrin; Male; Neoplasm Staging; Precancerous Conditions; Rats; Rats, Inbred F344 | 1997 |
Mutations of the Apc gene in experimental colorectal carcinogenesis induced by azoxymethane in F344 rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colorectal Neoplasms; DNA, Neoplasm; Epithelium; Genes, APC; Intestinal Mucosa; Male; Mutation; Polymerase Chain Reaction; Precancerous Conditions; Rats; Rats, Inbred F344 | 1998 |
Fasting/re-feeding before initiation enhances the growth of aberrant crypt foci induced by azoxymethane in rat colon and rectum.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogens; Cell Division; Colonic Neoplasms; Eating; Fasting; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Rectal Neoplasms; Weight Loss | 1998 |
Inhibitory effect of Coptidis Rhizoma and Scutellariae Radix on azoxymethane-induced aberrant crypt foci formation in rat colon.
Topics: Animals; Azoxymethane; Berberine; Colonic Neoplasms; Dose-Response Relationship, Drug; Flavonoids; Male; Plant Extracts; Plants, Medicinal; Precancerous Conditions; Rats; Rats, Inbred F344 | 1998 |
Azoxymethane-induced colon tumors and aberrant crypt foci in mice of different genetic susceptibility.
Topics: Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Disease Susceptibility; Male; Mice; Mice, Inbred A; Mice, Inbred AKR; Mice, Inbred Strains; Phenotype; Precancerous Conditions; Species Specificity | 1998 |
Inhibition of azoxymethane initiated colon tumor and aberrant crypt foci development by bovine lactoferrin administration in F344 rats.
Topics: Animals; Azoxymethane; Carcinogens; Cattle; Colon; Colonic Neoplasms; Lactoferrin; Male; Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Inbred F344 | 1998 |
Long-term analysis of colonic aberrant crypt formation after treatment of Sprague-Dawley rats with azoxymethane.
Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Male; Mutation; Polymorphism, Single-Stranded Conformational; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1998 |
Prevention of colon cancer by pre- and probiotics: evidence from laboratory studies.
Topics: Animals; Azoxymethane; Bifidobacterium; Carcinogens; Cell Division; Colonic Neoplasms; Dietary Fiber; Freeze Drying; Intestinal Mucosa; Inulin; Male; Oncogene Protein p21(ras); Ornithine Decarboxylase; Precancerous Conditions; Probiotics; Rats; Rats, Inbred F344 | 1998 |
The chemopreventive role of ursodeoxycholic acid in azoxymethane-treated rats: suppressive effects on enhanced group II phospholipase A2 expression in colonic tissue.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colonic Neoplasms; DNA Primers; Gastrointestinal Agents; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Immunoblotting; Male; Phospholipases A; Phospholipases A2; Precancerous Conditions; Prostaglandins; Random Allocation; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Ursodeoxycholic Acid | 1998 |
Effect of retinoids on AOM-induced colon cancer in rats: modulation of cell proliferation, apoptosis and aberrant crypt foci.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Body Weight; Carcinogens; Colon; Colonic Neoplasms; Drug Screening Assays, Antitumor; Fenretinide; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Tretinoin | 1999 |
Prevention by aspirin and its combination with alpha-difluoromethylornithine of azoxymethane-induced tumors, aberrant crypt foci and prostaglandin E2 levels in rat colon.
Topics: Animals; Aspirin; Azoxymethane; Colon; Colonic Neoplasms; Dinoprostone; Dose-Response Relationship, Drug; Eflornithine; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1999 |
Prevention of colonic preneoplastic lesions by the probiotic Lactobacillus acidophilus NCFMTM in F344 rats.
Topics: Animals; Azoxymethane; Choristoma; Colonic Neoplasms; Glucuronidase; Lactobacillus acidophilus; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Risk Factors | 1999 |
Chemoprevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colonic Diseases; Colonic Neoplasms; Curcumin; Cyclooxygenase 2; Enzyme Inhibitors; Intestinal Mucosa; Isoenzymes; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Inbred F344; Thiourea | 1999 |
Energy restriction modulates the development of advanced preneoplastic lesions depending on the level of fat in the diet.
Topics: Analysis of Variance; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Corn Oil; Dietary Fats; Energy Intake; Male; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344 | 1999 |
Quantitative assessment of azoxymethane-induced aberrant crypt foci in inbred mice.
Topics: Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Epithelial Cells; Intestinal Mucosa; Mice; Mice, Inbred AKR; Mice, Inbred Strains; Precancerous Conditions | 1999 |
Tumor-enhancing effects of cholic acid are exerted on the early stages of colon carcinogenesis via induction of aberrant crypt foci with an enhanced growth phenotype.
Topics: Animals; Azoxymethane; Bile Acids and Salts; Carcinogens; Cholic Acid; Colon; Colonic Neoplasms; Drug Synergism; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors | 1998 |
Polyethylene-glycol, a potent suppressor of azoxymethane-induced colonic aberrant crypt foci in rats.
Topics: Animals; Azoxymethane; Bile Acids and Salts; Carcinogens; Colon; Colonic Neoplasms; Diet; Feces; Female; Polyethylene Glycols; Precancerous Conditions; Rats; Rats, Inbred F344; Surface-Active Agents; Weight Gain | 1999 |
Azoxymethane-induced aberrant crypt foci and colorectal tumors in F344 rats: sequential analysis of growth.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinoma, Signet Ring Cell; Cell Division; Colorectal Neoplasms; Hyperplasia; Intestinal Mucosa; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1999 |
Modifying effects of a flavonoid morin on azoxymethane-induced large bowel tumorigenesis in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Antioxidants; Azoxymethane; Carcinogens; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Glutathione Transferase; Male; Polyamines; Precancerous Conditions; Rats; Rats, Inbred F344 | 1999 |
Feeding soybean resistant protein to rats raises fecal bile acid excretion but counteracts a deoxycholate-caused decrease in colonic aberrant crypt foci.
Topics: Animals; Azoxymethane; Bile Acids and Salts; Blood Proteins; Carcinogens; Chromatography, Thin Layer; Colonic Neoplasms; Deoxycholic Acid; Feces; Lipids; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Soybean Proteins | 1999 |
Effects of roselle (Hibiscus sabdariffa Linn.), a Thai medicinal plant, on the mutagenicity of various known mutagens in Salmonella typhimurium and on formation of aberrant crypt foci induced by the colon carcinogens azoxymethane and 2-amino-1-methyl-6-ph
Topics: Animals; Anticarcinogenic Agents; Antimutagenic Agents; Azoxymethane; Chemoprevention; Colonic Neoplasms; DNA Methylation; Imidazoles; Liver Neoplasms; Malvaceae; Mutagenicity Tests; Mutagens; Neoplasm Staging; Plant Extracts; Plants, Medicinal; Precancerous Conditions; Rats; Rats, Inbred F344; Salmonella typhimurium; Thailand | 1999 |
Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis.
Topics: Animals; Azoxymethane; Bridged Bicyclo Compounds; Caproates; Colonic Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Precancerous Conditions; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype | 1999 |
Polyethylene-glycol suppresses colon cancer and causes dose-dependent regression of azoxymethane-induced aberrant crypt foci in rats.
Topics: Animals; Azoxymethane; Body Weight; Colorectal Neoplasms; Dose-Response Relationship, Drug; Feces; Female; Male; Polyethylene Glycols; Precancerous Conditions; Rats; Rats, Inbred F344 | 1999 |
Termination of piroxicam treatment and the occurrence of azoxymethane-induced colon cancer in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azoxymethane; Body Weight; Carcinogenicity Tests; Carcinogens; Cell Division; Colonic Neoplasms; Disease Progression; Drug Administration Schedule; Intestinal Mucosa; Male; Piroxicam; Precancerous Conditions; Rats; Rats, Inbred F344 | 1999 |
Suppression of azoxymethane-induced colonic aberrant crypt foci by a nitric oxide synthase inhibitor.
Topics: Animals; Anticarcinogenic Agents; Antigens, Nuclear; Azoxymethane; Body Weight; Carcinogens; Cell Division; Cell Nucleus; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nuclear Proteins; Precancerous Conditions; Rats; Rats, Inbred F344 | 2000 |
Colon cancer is induced by a single low dose of azoxymethane in fasted-refed rats.
Topics: Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Fasting; Food; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Rectal Neoplasms; Rectum | 1999 |
Mice overexpressing progastrin are predisposed for developing aberrant colonic crypt foci in response to AOM.
Topics: Animals; Azoxymethane; Bromodeoxyuridine; Carcinogens; Colon; Colonic Neoplasms; Disease Susceptibility; Gastrins; Humans; Mice; Mice, Inbred Strains; Mice, Transgenic; Precancerous Conditions; Protein Precursors | 2000 |
Evaluation of flutamide genotoxicity in rats and in primary human hepatocytes.
Topics: Androgen Antagonists; Animals; Antineoplastic Agents, Hormonal; Azoxymethane; Colon; Colonic Neoplasms; Comet Assay; Diethylnitrosamine; DNA Damage; DNA Fragmentation; Female; Flutamide; Humans; Liver; Liver Neoplasms; Male; Micronucleus Tests; Middle Aged; Mutagens; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 2000 |
Promotion of intestinal carcinogenesis by Streptococcus bovis.
Topics: Adenoma; Animals; Azoxymethane; Biogenic Polyamines; Cell Division; Cocarcinogenesis; Colon; Interleukin-8; Intestinal Neoplasms; Male; Precancerous Conditions; Rats; Rats, Wistar; Streptococcus bovis | 2000 |
Inhibitory effect of a prostaglandin E receptor subtype EP(1) selective antagonist, ONO-8713, on development of azoxymethane-induced aberrant crypt foci in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Azoxymethane; Cinnamates; Colonic Neoplasms; Male; Mice; Mice, Inbred C57BL; Precancerous Conditions; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype | 2000 |
Consistent and fast inhibition of colon carcinogenesis by polyethylene glycol in mice and rats given various carcinogens.
Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Dietary Fats; Dose-Response Relationship, Drug; Female; Male; Methylnitrosourea; Mice; Polyethylene Glycols; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Time Factors | 2000 |
Preventive effect of soybean resistant proteins against experimental tumorigenesis in rat colon.
Topics: Animals; Azoxymethane; Bile Acids and Salts; Carcinogens; Caseins; Cholesterol; Colonic Neoplasms; Deoxycholic Acid; Feces; Lipids; Male; Molecular Weight; Precancerous Conditions; Rats; Rats, Inbred F344; Soybean Proteins; Steroids | 2000 |
Altered expression of beta-catenin, inducible nitric oxide synthase and cyclooxygenase-2 in azoxymethane-induced rat colon carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Gene Expression; Genes, ras; Hyperplasia; Isoenzymes; Male; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Subcellular Fractions; Trans-Activators | 2000 |
Suppressive effect of the herbal medicine Oren-gedoku-to on cyclooxygenase-2 activity and azoxymethane-induced aberrant crypt foci development in rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drugs, Chinese Herbal; Isoenzymes; Male; Membrane Proteins; Plant Extracts; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344 | 2000 |
Modifying effects of ferulic acid on azoxymethane-induced colon carcinogenesis in F344 rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Coumaric Acids; Diet; Glutathione Transferase; Intestinal Mucosa; Liver; Male; NAD(P)H Dehydrogenase (Quinone); Precancerous Conditions; Rats; Rats, Inbred F344 | 2000 |
Frequent beta-catenin gene mutations and accumulations of the protein in the putative preneoplastic lesions lacking macroscopic aberrant crypt foci appearance, in rat colon carcinogenesis.
Topics: Amino Acid Substitution; Animals; Azoxymethane; beta Catenin; Cadherins; Colon; Colonic Neoplasms; Cytoskeletal Proteins; Intestinal Mucosa; Male; Point Mutation; Precancerous Conditions; Rats; Rats, Inbred F344; Trans-Activators | 2000 |
Morphodensitometric analysis of protein kinase C beta(II) expression in rat colon: modulation by diet and relation to in situ cell proliferation and apoptosis.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogens; Cell Cycle; Cell Division; Cellulose; Colon; Colonic Neoplasms; Corn Oil; Diet; Fatty Acids, Omega-3; Immunohistochemistry; Isoenzymes; Male; Pectins; Precancerous Conditions; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Sprague-Dawley; Subcellular Fractions | 2000 |
Phytic acid in wheat bran affects colon morphology, cell differentiation and apoptosis.
Topics: Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Carcinogens; Cell Differentiation; Colon; Colonic Neoplasms; Dietary Fiber; Intestinal Mucosa; Lectins; Male; Mucins; Phytic Acid; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344 | 2000 |
Sequential and morphological analyses of aberrant crypt foci formation in mice of differing susceptibility to azoxymethane-induced colon carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Disease Susceptibility; Drug Resistance; Mice; Mice, Inbred A; Mice, Inbred AKR; Precancerous Conditions; Species Specificity | 2000 |
Resveratrol depresses the growth of colorectal aberrant crypt foci by affecting bax and p21(CIP) expression.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Azoxymethane; bcl-2-Associated X Protein; Carcinogens; Cell Division; Colon; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Growth Inhibitors; Intestinal Mucosa; Male; Precancerous Conditions; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred F344; Rectum; Resveratrol; Stilbenes | 2000 |
Differential expression of p16(INK4a) in azoxymethane-induced mouse colon tumorigenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, p16; Genes, Retinoblastoma; Male; Mice; Mice, Inbred Strains; Neoplasm Proteins; Polymerase Chain Reaction; Precancerous Conditions; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm | 2000 |
Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Cyclin D1; Female; Intestinal Mucosa; Male; Mice; Precancerous Conditions; Quercetin; Rutin | 2000 |
Detection of somatic DNA alterations in azoxymethane-induced F344 rat colon tumors by random amplified polymorphic DNA analysis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; DNA Damage; DNA Fingerprinting; DNA, Neoplasm; Genes, ras; Male; Microsatellite Repeats; Mutation; Precancerous Conditions; Random Amplified Polymorphic DNA Technique; Rats; Rats, Inbred F344 | 2000 |
Inhibitory effects of crude salts on the induction and development of colonic aberrant crypt foci in F-344 rats given azoxymethane.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Salts; Sodium Chloride, Dietary | 2000 |
The effects of dietary selenomethionine on polyamines and azoxymethane-induced aberrant crypts.
Topics: Alanine Transaminase; Animals; Anticarcinogenic Agents; Azoxymethane; Biogenic Polyamines; Body Weight; Carcinogens; Colon; Colonic Neoplasms; Dietary Supplements; Dose-Response Relationship, Drug; Intestinal Mucosa; Liver; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Selenium; Selenomethionine | 2000 |
Increased susceptibility of adult rats to azoxymethane-induced aberrant crypt foci.
Topics: Age Factors; Animals; Azoxymethane; beta Catenin; Bromodeoxyuridine; Carcinogens; Cecum; Cell Division; Colon; Colonic Diseases; Cytoskeletal Proteins; Disease Susceptibility; Female; Immunohistochemistry; Mutation; Polymorphism, Single-Stranded Conformational; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Rectum; Sodium Chloride; Time Factors; Trans-Activators | 2000 |
Folate deficiency diminishes the occurrence of aberrant crypt foci in the rat colon but does not alter global DNA methylation status.
Topics: Animals; Azoxymethane; Carcinogens; Chromatography, High Pressure Liquid; Colon; Colonic Neoplasms; Data Interpretation, Statistical; Disease Models, Animal; DNA Methylation; Folic Acid; Folic Acid Deficiency; Homocysteine; Injections, Subcutaneous; Intestinal Mucosa; Liver; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Risk Factors; Time Factors | 2000 |
Nitric oxide synthase inhibition promotes carcinogen-induced preneoplastic changes in the colon of rats.
Topics: Adenosylmethionine Decarboxylase; Animals; Azoxymethane; Biogenic Polyamines; Blood Pressure; Body Weight; Carcinogens; Colon; Cyclic GMP; Enzyme Inhibitors; Heart Rate; Intestinal Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ornithine Decarboxylase; Precancerous Conditions; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine | 2000 |
Carrageenan gel and aberrant crypt foci in the colon of conventional and human flora-associated rats.
Topics: Animals; Azoxymethane; Carcinogens; Carrageenan; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Feces; Female; Gels; Germ-Free Life; Molecular Weight; Precancerous Conditions; Rats; Rats, Inbred F344 | 2000 |
Neonatal inoculation with the protein-bound polysaccharide PSK increases resistance of adult animals to challenge with syngeneic tumor cells and reduces azoxymethane-induced precancerous lesions in the colon.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Age Factors; Animals; Animals, Newborn; Azoxymethane; Carcinogens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Precancerous Conditions; Proteoglycans; Rats; Rats, Inbred F344; Survival Analysis | 2000 |
Effect of dietary galacto-oligosaccharides on azoxymethane-induced aberrant crypt foci and colorectal cancer in Fischer 344 rats.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Body Weight; Carcinogens; Colorectal Neoplasms; Diet; Dose-Response Relationship, Drug; Eating; Energy Intake; Galactosides; Male; Oligosaccharides; Precancerous Conditions; Rats; Rats, Inbred F344 | 2001 |
Inhibition of azoxymethane-induced colon carcinogenesis in male F344 rats by the citrus limonoids obacunone and limonin.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Benzopyrans; Benzoxepins; Carcinogens; Colonic Neoplasms; Diet; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Eating; Limonins; Male; Pilot Projects; Precancerous Conditions; Rats; Rats, Inbred F344; Triterpenes | 2001 |
The inhibitory effects of mangiferin, a naturally occurring glucosylxanthone, in bowel carcinogenesis of male F344 rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Cell Division; Colonic Neoplasms; Drug Screening Assays, Antitumor; Intestinal Mucosa; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Xanthenes; Xanthones | 2001 |
Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Female; Genetic Predisposition to Disease; Immunohistochemistry; Isoenzymes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Precancerous Conditions; Protein Kinase C; Protein Kinase C beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Modulation of experimental colon tumorigenesis by types and amounts of dietary fatty acids.
Topics: Animals; Apoptosis; Arachidonic Acid; Azoxymethane; Body Weight; Carcinogens; Colonic Neoplasms; Corn Oil; Cyclooxygenase 1; Cyclooxygenase 2; Dietary Fats; Fatty Acids; Fish Oils; Intestinal Mucosa; Isoenzymes; Male; Membrane Proteins; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344 | 2001 |
Inhibitory effects of bitter melon (Momordica charantia Linn.) on bacterial mutagenesis and aberrant crypt focus formation in the rat colon.
Topics: Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; DNA Adducts; Male; Mutagenesis; Mutagenicity Tests; Mutagens; Plant Extracts; Precancerous Conditions; Rats; Rats, Inbred F344; Rosales; Salmonella typhimurium | 2001 |
Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Bezafibrate; Cell Division; Chromans; Colitis; Colonic Neoplasms; Dextran Sulfate; Growth Substances; Intestinal Mucosa; Ligands; Male; Mucins; Muscle Proteins; Neuropeptides; Nucleolus Organizer Region; Peptides; Precancerous Conditions; Proteins; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Silver Staining; Thiazoles; Thiazolidinediones; Transcription Factors; Trefoil Factor-2; Trefoil Factor-3; Troglitazone | 2001 |
Effects of indole-3-carbinol on immune responses, aberrant crypt foci, and colonic crypt cell proliferation in rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Biomarkers; Body Weight; Carcinogens; Cell Division; Colonic Neoplasms; Hypersensitivity, Delayed; Immunity; Immunoglobulin G; Immunohistochemistry; Indoles; Killer Cells, Natural; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Spleen | 2001 |
Suppression of azoxymethane-induced preneoplastic lesions and inhibition of cyclooxygenase-2 activity in the colonic mucosa of rats drinking a crude green tea extract.
Topics: Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Cyclooxygenase 2; Intestinal Mucosa; Isoenzymes; Male; Plant Extracts; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Tea | 2000 |
Troglitazone, a ligand for peroxisome proliferator-activated receptor gamma, inhibits chemically-induced aberrant crypt foci in rats.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Biogenic Polyamines; Carcinogens; Chromans; Colitis; Colonic Neoplasms; Dextran Sulfate; Intestinal Mucosa; Ligands; Male; Ornithine Decarboxylase; Precancerous Conditions; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2001 |
Suppression of occurrence and advancement of beta-catenin-accumulated crypts, possible premalignant lesions of colon cancer, by selective cyclooxygenase-2 inhibitor, celecoxib.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; beta Catenin; Celecoxib; Cell Division; Cell Nucleus; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Enzyme Inhibitors; Immunohistochemistry; Isoenzymes; Male; Nucleolus Organizer Region; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred F344; Sulfonamides; Time Factors; Trans-Activators | 2001 |
Qualitative and quantitative relationship between dysplastic aberrant crypt foci and tumorigenesis in the Min/+ mouse colon.
Topics: Adenoma; Adenomatous Polyposis Coli; Alleles; Animals; Azoxymethane; beta Catenin; Carcinogens; Cell Division; Cocarcinogenesis; Colonic Neoplasms; Cytoskeletal Proteins; Female; Genes, APC; Genetic Predisposition to Disease; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Precancerous Conditions; Trans-Activators | 2001 |
High susceptibility of Scid mice to colon carcinogenesis induced by azoxymethane indicates a possible caretaker role for DNA-dependent protein kinase.
Topics: Adenocarcinoma; Animals; Azoxymethane; beta Catenin; Carcinogens; Cocarcinogenesis; Colonic Neoplasms; Cytoskeletal Proteins; DNA-Activated Protein Kinase; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Mice; Mice, SCID; Mutation; Precancerous Conditions; Protein Serine-Threonine Kinases; Trans-Activators | 2001 |
Effect of bisacodyl and cascara on growth of aberrant crypt foci and malignant tumors in the rat colon.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Bisacodyl; Carcinogens; Colon; Colonic Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Precancerous Conditions; Rats; Rats, Wistar; Rhamnus | 2001 |
Chemoprevention of azoxymethane-induced rat aberrant crypt foci by dietary zerumbone isolated from Zingiber zerumbet.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Cell Division; Colon; Colonic Neoplasms; Cyclooxygenase 2; Diet; Dinoprostone; Dose-Response Relationship, Drug; Glutathione Transferase; Intestinal Mucosa; Isoenzymes; Liver; Male; NAD(P)H Dehydrogenase (Quinone); Nucleolus Organizer Region; Precancerous Conditions; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Sesquiterpenes; Silver Staining; Zingiberaceae | 2001 |
Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol.
Topics: Animals; Azoxymethane; Biotransformation; Carcinogens; Colon; Cytochrome P-450 CYP2E1; DNA; DNA Methylation; Female; Guanine; Liver; Male; Methylazoxymethanol Acetate; Mice; Precancerous Conditions | 2001 |
Short term infusion of glycine-extended gastrin(17) stimulates both proliferation and formation of aberrant crypt foci in rat colonic mucosa.
Topics: Animals; Azoxymethane; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Gastrins; Glycine; Hormones; Male; Mucous Membrane; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors | 2001 |
Inhibition of azoxymethane-induced aberrant crypt foci formation in rat colorectum by whole leaf Aloe arborescens Miller var. natalensis Berger.
Topics: Aloe; Animals; Antineoplastic Agents; Azoxymethane; Colorectal Neoplasms; Liver; Male; NAD(P)H Dehydrogenase (Quinone); Phytotherapy; Plant Extracts; Plant Leaves; Precancerous Conditions; Rats; Rats, Inbred F344 | 2001 |
Effect of grape seed proanthocyanidins on colon aberrant crypts and breast tumors in a rat dual-organ tumor model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthocyanins; Azoxymethane; Carcinogens; Colonic Neoplasms; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Female; Glutathione Transferase; Liver; Mammary Neoplasms, Experimental; Ornithine Decarboxylase; Precancerous Conditions; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Seeds; Vitis | 2001 |
Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Dinoprostone; Female; Intestinal Polyps; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Precancerous Conditions; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger | 2002 |
Synergistic effects of (-)-epigallocatechin gallate with sulindac against colon carcinogenesis of rats treated with azoxymethane.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azoxymethane; Carcinogens; Catechin; Choristoma; Colon; Colonic Neoplasms; Drug Synergism; In Situ Nick-End Labeling; Incidence; Male; Nucleolus Organizer Region; Precancerous Conditions; Rats; Rats, Inbred F344; Sulindac; Tea | 2002 |
Studies on cancer chemoprevention by traditional folk medicines XXV. Inhibitory effect of isoliquiritigenin on azoxymethane-induced murine colon aberrant crypt focus formation and carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Azoxymethane; Chalcone; Chalcones; Colonic Neoplasms; Male; Mice; Precancerous Conditions | 2002 |
Dietary conjugated linolenic acid inhibits azoxymethane-induced colonic aberrant crypt foci in rats.
Topics: Animals; Antioxidants; Apoptosis; Azoxymethane; Colonic Neoplasms; Dietary Fats, Unsaturated; Fatty Acids; Linoleic Acid; Male; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2002 |
Enhanced growth of colorectal aberrant crypt foci in fasted/refed rats involves changes in TGFbeta1 and p21CIP expressions.
Topics: Animals; Azoxymethane; Carcinogens; Cell Division; Colon; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Food Deprivation; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Kinetics; Male; Mucous Membrane; Precancerous Conditions; Rats; Rats, Inbred F344; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
Induction of apoptosis by sulindac in azoxymethane-induced possible colonic premalignant lesions in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Azoxymethane; beta Catenin; Carcinogens; Cell Division; Cell Nucleus; Colonic Neoplasms; Cytoskeletal Proteins; Diet; In Situ Nick-End Labeling; Incidence; Male; Nucleolus Organizer Region; Precancerous Conditions; Rats; Rats, Inbred F344; Silver; Sulindac; Trans-Activators | 2002 |
Conjugated linoleic acid does not inhibit development of aberrant crypt foci in colons of male Sprague-Dawley rats.
Topics: Animals; Azoxymethane; Colon; Colonic Neoplasms; Insulin; Linoleic Acid; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 2001 |
Effect of simple phenolic compounds on azoxymethane-induced aberrant crypt foci in rat colon.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Colon; Colonic Neoplasms; Coumaric Acids; Diet; Flavonoids; Hydroxybenzoates; Male; Parabens; Phenols; Precancerous Conditions; Rats; Rats, Inbred F344 | 2001 |
Hyperplasia and neoplasia of the intestinal tract.
Topics: Adaptation, Physiological; Animals; Azoxymethane; Cell Division; DNA; Intestinal Mucosa; Intestinal Neoplasms; Intestines; Male; Methods; Neoplasms, Experimental; Postoperative Complications; Precancerous Conditions; Rats; RNA; Time Factors | 1979 |
The effect of high-risk and low-risk diets on aberrant crypt and colonic tumor formation in Fischer-344 rats.
Topics: Animals; Azoxymethane; Body Weight; Calcium, Dietary; Colon; Colonic Neoplasms; Dietary Fats; Dietary Fiber; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1992 |
Aberrant crypts correlate with tumor incidence in F344 rats treated with azoxymethane and phytate.
Topics: Animals; Azoxymethane; Colonic Neoplasms; Phytic Acid; Precancerous Conditions; Rats; Rats, Inbred F344 | 1992 |
Evidence for a ras gene mutation in azoxymethane-induced colonic aberrant crypts in Sprague-Dawley rats: earliest recognizable precursor lesions of experimental colon cancer.
Topics: Adenocarcinoma; Animals; Azoxymethane; Base Sequence; Colonic Neoplasms; DNA, Single-Stranded; Genes, ras; Immunohistochemistry; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Precancerous Conditions; Proto-Oncogene Proteins p21(ras); Rats; Rats, Sprague-Dawley | 1992 |
Effect of dietary oxidized cholesterol on azoxymethane-induced colonic preneoplasia in mice.
Topics: Analysis of Variance; Animals; Azoxymethane; Cholesterol, Dietary; Colonic Neoplasms; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oxidation-Reduction; Precancerous Conditions; Sterols | 1992 |
Aberrant crypt foci and microadenoma as markers for colon cancer.
Topics: Adenoma; Animals; Azoxymethane; Cocarcinogenesis; Colonic Neoplasms; Diet; Hot Temperature; Mice; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344 | 1992 |
Dietary cholesterol enhances the induction and development of colonic preneoplastic lesions in C57BL/6J and BALB/cJ mice treated with azoxymethane.
Topics: Animals; Azoxymethane; Cell Division; Cholesterol, Dietary; Cocarcinogenesis; Colorectal Neoplasms; Female; Intestines; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Precancerous Conditions | 1992 |
Dietary cholesterol enhances preneoplastic aberrant crypt formation and alters cell proliferation in the murine colon treated with azoxymethane.
Topics: Analysis of Variance; Animals; Azoxymethane; Cell Count; Cell Division; Cholesterol, Dietary; Colonic Neoplasms; Disease Susceptibility; Female; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Precancerous Conditions; Random Allocation | 1992 |
Evaluation of dietary dehydroepiandrosterone for chemoprotection against tumorigenesis in premalignant colonic epithelium of male F344 rats.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Dehydroepiandrosterone; Diet; Dimethylhydrazines; Epithelium; Male; Muscle, Smooth; Precancerous Conditions; Rats; Rats, Inbred F344; Reference Values | 1991 |
Prevention by chemopreventive agents of azoxymethane-induced foci of aberrant crypts in rat colon.
Topics: Acetylcysteine; Allyl Compounds; Animals; Anticarcinogenic Agents; Azoxymethane; Colon; Colonic Neoplasms; Dehydroepiandrosterone; Eflornithine; Ellagic Acid; Isothiocyanates; Male; Precancerous Conditions; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Sulfides; Thiazoles; Thiazolidines; Thiocyanates | 1991 |
Effect of disulfiram on 1,2-dimethylhydrazine- and azoxymethane-induced aberrant crypt foci.
Topics: 1,2-Dimethylhydrazine; Animals; Azoxymethane; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Disulfiram; Female; Intestinal Mucosa; Mice; Precancerous Conditions | 1991 |
Dietary butyrate (tributyrin) does not enhance AOM-induced colon tumorigenesis.
Topics: Animals; Azo Compounds; Azoxymethane; Body Weight; Cocarcinogenesis; Colonic Neoplasms; Diet; Drug Evaluation, Preclinical; Fatty Acids; Feces; Female; Mice; Precancerous Conditions; Triglycerides | 1990 |
Dietary manipulation during experimental colorectal carcinogenesis: a morphological study in the rat.
Topics: Animals; Azoxymethane; Colon; Colonic Neoplasms; Dietary Fats; Dietary Fiber; Intestinal Mucosa; Male; Precancerous Conditions; Rats | 1987 |
Aberrant crypts: potential preneoplastic lesions in the murine colon.
Topics: Animals; Azoxymethane; Colonic Neoplasms; Dietary Fats; Dose-Response Relationship, Drug; Mice; Mice, Inbred C57BL; Precancerous Conditions; Species Specificity | 1988 |
Changes in crypt cell DNA content during experimental colonic carcinogenesis.
Topics: Animals; Azoxymethane; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; DNA; Intestinal Mucosa; Male; Precancerous Conditions; Rats; Rats, Inbred Strains | 1986 |
Effect of warfarin on formation and growth of pre-neoplastic lesions in chemically induced colorectal cancer in the rat.
Topics: Adenoma; Animals; Azoxymethane; Colon; Colonic Neoplasms; Disease Models, Animal; Intestinal Mucosa; Male; Microscopy, Electron, Scanning; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred Strains; Rectal Neoplasms; Rectum; Warfarin | 1986 |