Page last updated: 2024-08-23

azoxymethane and Inflammation

azoxymethane has been researched along with Inflammation in 130 studies

Research

Studies (130)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (9.23)29.6817
2010's79 (60.77)24.3611
2020's39 (30.00)2.80

Authors

AuthorsStudies
Donthi, D; Hong, H; Lertpiriyapong, K; Marie, MA; Sanderlin, EJ; Satturwar, S; Yang, LV1
Chen, GQ; Chen, J; Li, Z; Liu, G; Wu, F; Zhang, S; Zhang, Y1
Bou-Dargham, M; Chen, YH; Etwebi, Z; Goldsmith, JR; Hood, R; Lengner, C; Li, M; Liu, S; Lou, Y; Spitofsky, N; Sun, H; Tian, Y1
Deng, J; Han, L; Li, Y; Shi, J; Wang, H; Yan, Y; Yuan, X; Zhang, H; Zhao, H; Zhao, L; Zhao, Y; Zou, F1
Jiang, S; Ma, F; Mu, G; Qian, F; Song, Y; Sun, M; Tuo, Y; Wang, A1
Chen, K; Gao, Z; Jia, H; Shi, Y; Wang, Z; Yuan, Y; Yue, T; Zeng, X1
Dong, S; Ismael, M; Lü, X; Shan, Y; Wang, T; Wang, X; Zheng, J1
Chen, Y; Diao, T; Li, D; Shang, G; Shi, L; Sun, L; Yin, X1
Chen, Q; Fu, J; Han, H; Lin, H; Lu, G; Ma, X; Qi, J; Wen, Z; Yang, M; Yang, X; Yang, Y; Yin, T1
Ajayi, BO; Ajeigbe, OF; Anyebe, DA; Farombi, EO; Maruf, OR; Opafunso, IT1
Archer, A; Birgersson, M; Hases, L; Indukuri, R; Williams, C1
Ando, Y; Aoi, M; Fukui, T; Horitani, S; Matsumoto, Y; Naganuma, M; Okazaki, K; Tanaka, H; Tomiyama, T; Tsuneyama, K; Uragami, T1
Huang, XH; Jiang, B; Ni, M; Wang, L; Xu, YY; Zhang, QQ; Zhang, R; Zhang, YQ; Zhao, Q1
Fan, RJ; Fang, MD; Ren, J; Tu, LL; Yao, WX; Zhang, YM; Zuo, BW1
Bullard, BM; Cardaci, TD; Fan, D; Hofseth, LJ; Huss, AR; McDonald, SJ; Murphy, EA; VanderVeen, BN1
Chung, JH; Hong, GH; Lee, SY; Park, KY1
Chen, Y; Li, P; Liang, J; Luo, X; Wang, Q; Xie, X; Yang, C; Zhang, M; Zhou, L1
Beck, S; Crossland, NA; Crott, JW; Guo, W; Lo, M; Mason, JB; Tan, WY; Zhang, C1
Chen, X; Decker, EA; Kim, D; Ma, Q; Park, Y; Qi, W; Sanidad, KZ; Yang, R; Zhang, G; Zhang, J1
Chen, X; Han, W; Li, Y; Shi, L; Wan, J; Wang, H; Xie, B1
Chia, YC; Fu, YS; Lin, SR; Lue, SI; Tsai, MJ; Tseng, FJ; Weng, CF; Woon, M; Zheng, JH1
Eun, CS; Han, DS; Jo, SV; Lee, AR; Lee, JG; Park, CH1
Chen, D; Huang, Z; Liu, Y; Ma, H; Ouyang, G; Wang, J; Wu, T; Zhao, X1
Berhow, M; Gonzalez de Mejia, E; Luna-Vital, D; Mazewski, C1
Benninghoff, AD; Hintze, KJ; Hunter, AH; Monsanto, SP; Pestka, JJ; Phatak, S; Rodriguez, DM; Ward, RE; Wettere, AJV1
Crott, JW; Kane, AV; Koh, GY; Wu, X1
Lin, L; Lin, Y; Qu, S; Wang, D; Zhao, H1
Akbari, A; Asadollahi, P; Ghanavati, R; Javadi, A; Mohammadi, F; Rohani, M; Talebi, M1
Alcalde, A; Arias, MA; Bird, PI; Camerer, E; Castro, M; Comas, L; Del Campo, R; Ferrandez, A; Galvez, EM; Garrido, M; Garzón, M; Gil-Gómez, G; Jaime-Sanchez, P; Lanuza, PM; Layunta, E; Martínez-Lostao, L; Metkar, S; Moreno, V; Muñoz, G; Pardo, J; Pelegrín, P; Peña, R; Ramirez-Labrada, A; Santiago, L; Sanz-Pamplona, R; Tapia, E; Uranga, JA; Uranga-Murillo, I1
Deng, T; Liu, M; Wan, X; Xie, W1
Devaraj, H; Seetha, A; Sudhandiran, G1
Bohnenberger, H; Meers, GK; Muzzi, C; Reichardt, HM; Reichardt, SD; Twomey, E; Watanabe, N1
Boonsanay, V; Brabletz, T; Greten, FR; Heichler, C; Neufert, C; Neurath, MF; Scheibe, K1
Im, S; Jiang, Q; Jones-Hall, Y; Nakatsu, C; Yang, C; Zhao, Y1
Epifano, F; Fiorito, S; Genovese, S; Ibuka, T; Ideta, T; Kubota, M; Maruta, A; Miyazaki, T; Mizutani, T; Sakai, H; Shimizu, M; Shirakami, Y; Taddeo, VA; Tanaka, T1
Board, PG; Casarotto, MG; Dahlstrom, JE; Fernando, N; Hughes, MM; O'Neill, LAJ; Rooke, M; Takahashi, S; Tummala, P1
Hiramoto, K; Kawanishi, S; Ma, N; Murata, M; Ohnishi, S; Wang, G; Yoshikawa, N1
Ibuka, T; Ideta, T; Kochi, T; Kubota, M; Nakanishi, T; Ozawa, N; Sakai, H; Shimizu, M; Shirakami, Y; Tanaka, T1
Esa, NM; Ishak, NIM; Madzuki, IN; Mohamed, S; Mustapha, NM1
Lei, J; Wei, Y; Zhang, H; Zhou, R1
Chen, C; Chen, J; Chen, R; Fang, L; Guo, C; Guo, D; Sang, T; Wang, X; Wang, Y; Wu, J1
Cao, M; Chen, Y; Fu, B; Hu, R; Li, T; Tan, Y; Yang, M; Zhang, X; Zhou, Y1
An, HJ; Jin, BR; Kim, HJ; Lee, M; Sim, SA1
Arias-Romero, LE; Ávila-Moreno, F; Chirino, YI; Delgado-Buenrostro, NL; Delgado-Ramirez, YG; Gutierrez-Cirlos, EB; Ledesma-Soto, Y; Leon-Cabrera, SA; Molina-Guzman, E; Pérez-Plasencia, CG; Rodríguez-Sosa, M; Terrazas, LI; Vaca-Paniagua, F; Vázquez-Sandoval, A1
Dai, X; Gui, G; Li, K; Liu, J; Xiao, Y; Yang, H1
Berggren, KL; Beswick, EJ; Gan, GN; Ray, AL; Restrepo Cruz, S1
Lin, JA; Wu, CH; Yen, GC1
Arning, E; Ashcraft, P; Cook, B; Genta, RM; Han, J; Holm, J; Jackson, D; Souza, RF; Sweetman, L; Theiss, AL; Turner, K; Venuprasad, K; Wang, X1
An, HJ; Cheon, SY; Chung, KS; Lee, M; Roh, SS1
Agle, KA; Chen, X; Drobyski, WR; Huang, YW; Oshima, K; Pan, P; Wang, LS; Yearsley, MM; Yu, J; Zhang, J1
Cheng, D; Fang, M; Gao, L; Gaspar, JM; Guo, Y; Hart, RP; Kong, AN; Li, W; Sargsyan, D; Su, ZY; Verzi, MP; Wang, C; Wu, R; Yin, R; Zhang, C1
Gong, D; Hu, JL; Liu, LQ; Nie, SP; Shen, MY; Xie, MY; Yu, Q1
Allaman, MM; Asim, M; Barry, DP; Cleveland, JL; Coburn, LA; Delgado, AG; Gobert, AP; Luis, PB; Piazuelo, MB; Schneider, C; Shi, C; Singh, K; Washington, MK; Wilson, KT1
Chastre, E; Jordan, P; Kotelevets, L; Lehy, T; Mamadou, G; Walker, F1
Booth, CJ; D'Souza, SS; Kartchner, BJ; Lee, EC; Malizia, RA; O'Connor, W; Sharp, SP; Stain, SC; Walrath, T1
Balboa, MA; Balsinde, J; Cubero, Á; García-Rostán, G; Győrffy, B; Lordén, G; Meana, C; Orduña, A; Peña, L1
Kim, N; Lee, DH; Lee, SM; Na, HY; Nam, RH; Sohn, SH; Song, CH; Surh, YJ1
Arruda, SF; Campos, NA; da Cunha, MSB1
Chen, H; De Lisio, M; Emmons, R; Hernández-Saavedra, D; Kriska, A; Pan, YX; Xu, G1
Hwang, S; Khalmuratova, R; Kim, JH; Kim, YS; Koh, SJ; Lee, GY; Lee, M; Park, JW; Shin, HW; Yoon, DW1
Arthur, JC; Rothemich, A1
Bader, JE; Carson, JA; Carson, M; Chatzistamou, I; Enos, RT; Kubinak, JL; Murphy, EA; Nagarkatti, M; Pena, MM; Sougiannis, AT; VanderVeen, BN; Velazquez, KT; Walla, M1
Brahmaroutu, A; DeMorrow, S; Frampton, G; Grant, S; Jefferson, B; McMillin, M; Petrescu, AD; Thomas, A; Williams, E1
Imai, T; Ishigamori, R; Ito, K; Mutoh, M; Ohta, T; Takahashi, M1
Gao, Y; Li, X; Liu, X; Lu, X; Wang, G; Wu, J; Wu, Q; Yang, M; Yang, Y; Zhang, Y; Zhao, Q1
Agarwal, C; Agarwal, R; Balaiya, V; Derry, MM; Huber, KM; Jain, AK; Raina, K; Serkova, NJ; Shrotriya, S1
Allred, CD; Allred, KF; Armstrong, CM; Billimek, AR; Sturino, JM; Weeks, BR1
Barrett, CW; Bradley, AM; Burk, RF; Chaturvedi, R; Davies, SS; Fingleton, BM; Hill, KE; Lintel, MK; Matafonova, E; Motley, AK; Ning, W; Parang, B; Poindexter, SV; Reddy, VK; Singh, K; Washington, MK; Williams, CS; Wilson, KT1
Bélanger, M; Butterworth, RF; Chastre, A; Nguyen, BN1
Banerjee, N; Kim, H; Mertens-Talcott, S; Talcott, S1
Knackstedt, R; Moseley, V; Shaoli, S; Wargovich, M1
Aguirre, V; Bartuzi, P; Ben-Shlomo, S; Burstein, E; Chan, L; Esko, T; Faubion, WA; Franke, L; Gluck, N; Hofker, M; Kracht, M; Kumar, V; Li, H; Mao, X; Melton, SD; Metspalu, A; Mokadem, M; Raetz, M; Schneider, H; Starokadomskyy, P; van de Sluis, B; van Sommeren, S; Varol, C; Weber, A; Weersma, RK; Weisberg, R; Westra, HJ; Wijmenga, C; Yarovinsky, F1
Li, H; Li, S; Liang, X; Tian, G1
Miller, MA; Neufeld, KL; Sullivan, R; Zeineldin, M1
Alam, F; Byun, Y; Chung, SW; Jeon, OC; Kim, JY; Kim, SY; Park, J; Son, WC1
Hosono, A; Seki, T; Takai, S; Yamaguchi, M1
Ai, F; Bian, Y; Dang, W; Fan, S; Huang, J; Li, G; Li, N; Ma, J; Qin, Z; Tang, A; Xiong, W; Yan, Q; Ye, Q; Zhang, X; Zheng, Y; Zhou, M; Zhou, Y1
Chen, Z; He, X; He, Z; Ke, J; Lan, P; Lian, L; Sun, L; Wu, X1
Barnholtz-Sloan, JS; Chen, Y; Dawson, DM; Fink, SP; Kopelovich, L; Kresak, A; Lawrence, EG; Markowitz, SD; Willis, JE; Yang, P; Zhang, Y1
Abdella, EM; El-Derby, AM; Mahmoud, AM1
Burkitt, MD; Caamano, JH; Dimaline, R; Duckworth, CA; Gerondakis, S; Hanedi, AF; O'Reilly, LA; Pritchard, DM; Putoczki, TL; Tang, JM; Williams, JM1
Gold, B; Whetstone, RD1
Araki, K; Baba, H; Hirashima, K; Ida, S; Maehara, Y; Miyamoto, Y; Morita, M; Ohmuraya, M; Oki, E; Ozaki, N; Sakamoto, Y; Taki, K; Watanabe, M; Yamamura, K; Zaitsu, Y1
Hou, YY; Lv, MM; Nie, YZ; Ren, J; Shen, SN; Tang, RJ; Wang, TT; Xu, YJ; Zhao, XY1
Deng, Z; Egilmez, NK; Guo, H; Haribabu, B; Miller, D; Mu, J; Norris, J; Tseng, M; Wang, Q; Wattenberg, B; Yan, J; Zhang, HG; Zhang, L; Zhuang, X1
Han, SB; Hong, JT; Kim, EC; Park, KR; Yoon, DY; Yun, HM1
Matsui, H; Nagasaki, Y; Vong, LB; Yoshitomi, T1
Cai, Y; Golla, JP; Golla, S; Gonzalez, FJ; Korboukh, I; Krausz, KW; Manna, SK; Matsubara, T; Takahashi, S; Tanaka, N1
Bertino, P; Hara, JH; Hashimoto, AS; Hoffmann, FW; Hoffmann, PR; Huang, Z; Mafnas, C; Rose, AH1
Fukushima, T; Haruyama, Y; Itoh, H; Kanemaru, A; Kangawa, K; Kataoka, H; Kawaguchi, M; Matsumoto, N; Nakazato, M; Tanaka, H; Yamamoto, K1
Dammann, K; Evstatiev, R; Gasche, C; Harpain, F; Khare, V; Kurtovic, A; Lang, M; Mesteri, I1
Chinikaylo, A; Chittur, SV; Gutierrez, LS; Lawler, J; Lippert, B; Lopez-Dee, ZP; Patel, B; Patel, H1
Kim, H; Lee, HA; Lee, KW; Park, KY1
Chaudhry, KK; Gangwar, R; Manda, B; Meena, AS; Mir, H; Rao, R; Shukla, PK; Yadav, N1
Calvo, JA; Muthupalani, S; Samson, LD; Yu, AM1
Chaiyasut, C; Reungpatthanaphong, S; Sirilun, S; Suwannalert, P1
Cai, X; Cao, P; Chen, G; Cheng, X; Hu, C; Wang, M; Xu, Y; Yang, CS; Yang, Y1
de Carvalho, JE; Dmitrieva, O; Francescone, R; Grivennikov, SI; Hensley, H; Hou, V; Pilli, RA; Posocco, D; Vendramini-Costa, DB1
Han, J; Ishibashi, R; Kato, N; Kishikawa, T; Koike, K; Miyazawa, M; Nakagawa, R; Ohno, M; Otsuka, M; Suzuki, N; Takata, A; Wu, J; Yamagami, M; Yoshikawa, T1
Hayashi, SM; Hippo, Y; Kangawa, Y; Kihara, T; Maruyama, K; Nakamura, M; Ochiai, M; Okamoto, M; Shibutani, M; Yoshida, T1
Bielawski, J; Hannun, YA; Kaneshiro, T; Kawamori, T; Maalouf, S; Obeid, LM; Okumura, M; Uflacker, A1
Albert, PS; Barrett, KG; Bennink, MR; Bobe, G; Colburn, NH; Lanza, E; Mentor-Marcel, RA; Young, MR1
Hao, X; Ju, J; Lambert, JD; Lee, MJ; Lu, G; Newmark, HL; Xiao, H; Yang, CS1
Caderni, G; Dolara, P; Femia, AP; Luceri, C; Salvadori, M1
Chasson, L; Clément, A; Galland, F; Garcia, S; Hofman, P; Issaly, N; Millet, V; Naquet, P; Pouyet, L; Roisin-Bouffay, C; Rostan, A1
Koketsu, M; Oyama, T; Sugie, S; Tanaka, T; Watanabe, K; Yasui, Y1
An, MJ; Cheon, JH; Kim, HM; Kim, SA; Kim, SK; Kim, SW; Kim, TI; Kim, WH; Lee, SK; Park, JJ; Yang, KM1
Hata, K; Hirose, Y; Kubota, M; Moriwaki, H; Sakai, H; Shimizu, M; Shirakami, Y; Tanaka, T; Tsurumi, H; Yasuda, Y1
Bémeur, C; Butterworth, RF; Desjardins, P; Vaquero, J1
Bala, S; DeSchryver, K; Jiang, S; Levin, MS; Newberry, R; Onal, B; Rubin, DC; Shaker, A; Swietlicki, EA; Wang, L1
Abreu, MT; Cooper, HS; Elson, G; España, C; Fukata, M; Harpaz, N; Kosco-Vilbois, M; Lira, SA; Mayer, L; Pastorini, C; Perez, MT; Santaolalla, R; Shang, L; Sotolongo, J; Ungaro, R; Vamadevan, AS; Zaias, J1
Choi, KS; Chung, MH; Hahm, KB; Han, YM; Hong, H; Hong, KS; Kim, EH; Ock, CY1
Endlicher, E; Grunwald, N; Lechner, A; Neumann, ID; Obermeier, F; Peters, S; Reber, SO; Rümmele, P1
Li, TW; Lu, SC; Mato, JM; Peng, H; Xia, M; Yang, H1
Banning, A; Brauer, MN; Brigelius-Flohé, R; Chu, FF; Esworthy, RS; Florian, S; Iori, R; Kipp, AP; Krehl, S; Loewinger, M; Wessjohann, LA1
Cheong, SJ; Jang, D; Jeong, HJ; Jeong, MH; Kim, DW; Kim, EM; Lee, CM; Lim, ST; Sohn, MH1
Brubaker, PL; El-Zimaity, HM; Trivedi, S; Wiber, SC1
Boulard, O; Kirchberger, S; Maloy, KJ; Powrie, FM; Royston, DJ1
Behan, NA; Brooks, SP; Caldwell, D; Green, J; MacFarlane, AJ; Matias, FM1
Hara, A; Hatano, Y; Hirata, A; Hirose, Y; Kuno, T; Masuda, S; Mori, H; Tanaka, T; Terasaki, M; Tomita, H1
Agis-Torres, A; Bravo, L; Goya, L; López-Oliva, E; Martín, MA; Ramos, S; Rodríguez-Ramiro, I1
Butler, SM; Jeffery, EH; Jung, SH; Lee, EH; Nho, CW; Pan, CH; Wallig, MA1
Chitra, P; Manikandan, R; Saiprasad, G; Sudhandiran, G1
Kohno, H; Mori, H; Sugie, S; Suzuki, R; Tanaka, T; Yamada, Y1
Auwerx, J; Dubuquoy, L; Fayard, E; Geboes, K; Haby, C; Mebis, J; Schoonjans, K; Wendling, O1
Kohno, H; Sugie, S; Suzuki, R; Tanaka, T1
Bruce, WR; Hughes, R; Karlsson, PC; Rafter, JJ1
Miyamoto, S; Sugie, S; Suzuki, R; Tanaka, T; Yasui, Y1
Carroll, RE; Fernandez, PA; Hagos, GK; Kouznetsova, T; Li, Q; Swanson, SM; Thatcher, GR; Toader, V1
DuBois, RN; Radhika, A; Shattuck-Brandt, RL; Varilek, GW; Washington, MK; Yang, F1

Other Studies

130 other study(ies) available for azoxymethane and Inflammation

ArticleYear
GPR65 (TDAG8) inhibits intestinal inflammation and colitis-associated colorectal cancer development in experimental mouse models.
    Biochimica et biophysica acta. Molecular basis of disease, 2022, 01-01, Volume: 1868, Issue:1

    Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colon; Dextran Sulfate; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Humans; Inflammation; Inflammatory Bowel Diseases; Leukocytes; Mice; Mice, Knockout; Receptors, G-Protein-Coupled; Severity of Illness Index

2022
Applications and Mechanism of 3-Hydroxybutyrate (3HB) for Prevention of Colonic Inflammation and Carcinogenesis as a Food Supplement.
    Molecular nutrition & food research, 2021, Volume: 65, Issue:24

    Topics: 3-Hydroxybutyric Acid; Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL

2021
TIPE2 Promotes Tumor Initiation But Inhibits Tumor Progression in Murine Colitis-Associated Colon Cancer.
    Inflammatory bowel diseases, 2022, 05-04, Volume: 28, Issue:5

    Topics: Animals; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colitis-Associated Neoplasms; Colon; Dextran Sulfate; Disease Models, Animal; Inflammation; Inflammatory Bowel Diseases; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL

2022
Pre-Administration of Berberine Exerts Chemopreventive Effects in AOM/DSS-Induced Colitis-Associated Carcinogenesis Mice via Modulating Inflammation and Intestinal Microbiota.
    Nutrients, 2022, Feb-09, Volume: 14, Issue:4

    Topics: Animals; Azoxymethane; Berberine; Carcinogenesis; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Mice; Mice, Inbred C57BL; RNA, Ribosomal, 16S

2022
    Nutrients, 2022, May-03, Volume: 14, Issue:9

    Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Lactobacillaceae; Metabolome; Mice; Mice, Inbred C57BL

2022
    Food & function, 2022, Jul-04, Volume: 13, Issue:13

    Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Kefir; Lactobacillus; Mice; RNA, Ribosomal, 16S; Saccharomyces cerevisiae; Tibet

2022
Lacticaseibacillus rhamnosus LS8 Ameliorates Azoxymethane/Dextran Sulfate Sodium-Induced Colitis-Associated Tumorigenesis in Mice via Regulating Gut Microbiota and Inhibiting Inflammation.
    Probiotics and antimicrobial proteins, 2022, Volume: 14, Issue:5

    Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Dextran Sulfate; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Lacticaseibacillus rhamnosus; Mice

2022
Aspirin Inhibits Carcinogenesis of Intestinal Mucosal Cells in UC Mice Through Inhibiting IL-6/JAK/STAT3 Signaling Pathway and Modulating Apoptosis and Proliferation.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2022, Volume: 33, Issue:9

    Topics: Animals; Apoptosis; Aspirin; Azoxymethane; Carcinogenesis; Cell Proliferation; Colitis, Ulcerative; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Hyperplasia; Inflammation; Interleukin-10; Interleukin-6; Janus Kinases; Mice; Proliferating Cell Nuclear Antigen; Signal Transduction; STAT3 Transcription Factor

2022
Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer.
    International immunopharmacology, 2022, Volume: 111

    Topics: Animals; Azoxymethane; Bacteroidetes; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Firmicutes; Humans; Inflammation; Mice; Mice, Inbred C57BL; Naphthoquinones; Tumor Microenvironment

2022
6- shogaol suppresses AOM/DSS-mediated colorectal adenoma through its antioxidant and anti-inflammatory effects in mice.
    Journal of food biochemistry, 2022, Volume: 46, Issue:12

    Topics: Adenoma; Animals; Anti-Inflammatory Agents; Antioxidants; Azoxymethane; Colonic Neoplasms; Colorectal Neoplasms; Disease Models, Animal; Inflammation; Male; Mice

2022
Colitis Induces Sex-Specific Intestinal Transcriptomic Responses in Mice.
    International journal of molecular sciences, 2022, Sep-08, Volume: 23, Issue:18

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Humans; Inflammation; Inflammatory Bowel Diseases; Male; Mice; Mice, Inbred C57BL; Receptors, Glucocorticoid; RNA; Transcriptome

2022
Establishment of a Novel Colitis-Associated Cancer Mouse Model Showing Flat Invasive Neoplasia.
    Digestive diseases and sciences, 2023, Volume: 68, Issue:5

    Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Dextrans; Disease Models, Animal; Humans; Inflammation; Mice; Reproducibility of Results

2023
Ginsenoside Rb1 Suppresses AOM/DSS-induced Colon Carcinogenesis.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:9

    Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colorectal Neoplasms; Disease Models, Animal; Ginsenosides; Inflammation; Mice; Mice, Inbred C57BL; Tumor Microenvironment

2023
Boris knockout eliminates AOM/DSS-induced in situ colorectal cancer by suppressing DNA damage repair and inflammation.
    Cancer science, 2023, Volume: 114, Issue:5

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; DNA Damage; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout

2023
Panaxynol alleviates colorectal cancer in a murine model via suppressing macrophages and inflammation.
    American journal of physiology. Gastrointestinal and liver physiology, 2023, 10-01, Volume: 325, Issue:4

    Topics: Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mucins

2023
Anticancer Effects of Washed-Dehydrated Solar Salt Doenjang on Colon Cancer-Induced C57BL/6 Mice.
    Journal of medicinal food, 2023, Volume: 26, Issue:9

    Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Inflammation; Interleukin-6; Mice; Mice, Inbred C57BL; Sodium Chloride, Dietary; Tumor Necrosis Factor-alpha

2023
Astragaloside IV inhibits AOM/DSS-induced colitis-associated tumorigenesis via activation of PPARγ signaling in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 121

    Topics: Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Dextran Sulfate; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; PPAR gamma; Reactive Oxygen Species

2023
Fecal microbiota transplanted from old mice promotes more colonic inflammation, proliferation, and tumor formation in azoxymethane-treated A/J mice than microbiota originating from young mice.
    Gut microbes, 2023, Volume: 15, Issue:2

    Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Colonic Neoplasms; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Inflammation; Mice; Microbiota

2023
Thermally Processed Oil Exaggerates Colonic Inflammation and Colitis-Associated Colon Tumorigenesis in Mice.
    Cancer prevention research (Philadelphia, Pa.), 2019, Volume: 12, Issue:11

    Topics: Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Hot Temperature; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; Oils

2019
Orally Deliverable Nanotherapeutics for the Synergistic Treatment of Colitis-Associated Colorectal Cancer.
    Theranostics, 2019, Volume: 9, Issue:24

    Topics: Administration, Oral; Animals; Apoptosis; Azoxymethane; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colitis; Colorectal Neoplasms; Curcumin; Cytokines; Dextran Sulfate; Disease Models, Animal; Disease Progression; Drug Synergism; Female; Inflammation; Inflammation Mediators; Intestines; Irinotecan; Macrophages; Mice; Mice, Inbred C57BL; Nanoparticles; RAW 264.7 Cells

2019
Clerodane Diterpene Ameliorates Inflammatory Bowel Disease and Potentiates Cell Apoptosis of Colorectal Cancer.
    Biomolecules, 2019, 11-21, Volume: 9, Issue:12

    Topics: Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Caco-2 Cells; Cell Cycle; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dextran Sulfate; Diterpenes, Clerodane; Fluorouracil; HT29 Cells; Humans; Inflammation; Inflammatory Bowel Diseases; Intestines; Male; Mice, Inbred C57BL

2019
The impact of gut microbiota manipulation with antibiotics on colon tumorigenesis in a murine model.
    PloS one, 2019, Volume: 14, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Microbiome; High-Throughput Nucleotide Sequencing; Inflammation; Mice; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Tumor Burden

2019
Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation.
    Cell reports, 2020, 01-21, Volume: 30, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Adenomatous Polyposis Coli; Animals; Azoxymethane; Carcinogenesis; Cell Adhesion Molecules; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Focal Adhesion Protein-Tyrosine Kinases; Humans; Inflammation; Integrins; Interleukin-6; Intestines; Mice, Inbred C57BL; Myofibroblasts; Precancerous Conditions; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Stromal Cells; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins

2020
Reduction of colitis-associated colon carcinogenesis by a black lentil water extract through inhibition of inflammatory and immunomodulatory cytokines.
    Carcinogenesis, 2020, 07-10, Volume: 41, Issue:6

    Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Fabaceae; Gene Expression Profiling; Inflammation; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Water

2020
Consumption of the Total Western Diet Promotes Colitis and Inflammation-Associated Colorectal Cancer in Mice.
    Nutrients, 2020, Feb-20, Volume: 12, Issue:2

    Topics: Adaptive Immunity; Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Diet, Western; Disease Models, Animal; Immunity, Innate; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; RNA, Messenger

2020
Parabacteroides distasonis attenuates tumorigenesis, modulates inflammatory markers and promotes intestinal barrier integrity in azoxymethane-treated A/J mice.
    Carcinogenesis, 2020, 07-14, Volume: 41, Issue:7

    Topics: Animals; Azoxymethane; Bacteroidetes; Carcinogenesis; Colon; Colonic Neoplasms; Humans; Inflammation; Interleukin-4; Intestinal Mucosa; Mice; Obesity; Signal Transduction; Toll-Like Receptor 4; Transforming Growth Factor beta

2020
miR-370-3p Alleviates Ulcerative Colitis-Related Colorectal Cancer in Mice Through Inhibiting the Inflammatory Response and Epithelial-Mesenchymal Transition.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Animals; Azoxymethane; Cell Proliferation; Cells, Cultured; Colitis, Ulcerative; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Epithelial-Mesenchymal Transition; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; MicroRNAs

2020
Lactobacillus species inhibitory effect on colorectal cancer progression through modulating the Wnt/β-catenin signaling pathway.
    Molecular and cellular biochemistry, 2020, Volume: 470, Issue:1-2

    Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Female; Flow Cytometry; Gastrointestinal Microbiome; HT29 Cells; Humans; Inflammation; Lactobacillus; Mice; Mice, Inbred BALB C; Probiotics; Real-Time Polymerase Chain Reaction; Wnt Signaling Pathway

2020
Extracellular Granzyme A Promotes Colorectal Cancer Development by Enhancing Gut Inflammation.
    Cell reports, 2020, 07-07, Volume: 32, Issue:1

    Topics: Acute Disease; Animals; Azoxymethane; Carcinogenesis; Chronic Disease; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Disease Progression; Extracellular Space; Granzymes; Humans; Inflammasomes; Inflammation; Inflammation Mediators; Interleukin-6; Mice, Knockout; NF-kappa B; RNA, Messenger

2020
Clostridium butyricum modulates gut microbiota and reduces colitis associated colon cancer in mice.
    International immunopharmacology, 2020, Volume: 88

    Topics: Animals; Apoptosis; Azoxymethane; Bacteroidetes; Body Weight; Cell Proliferation; Clostridium butyricum; Colitis; Colitis-Associated Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Feces; Firmicutes; Gastrointestinal Microbiome; Inflammation; Male; Mice, Inbred C57BL; NF-kappa B p50 Subunit; RNA, Ribosomal, 16S

2020
Effects of combined treatment with Indomethacin and Juglone on AOM/DSS induced colon carcinogenesis in Balb/c mice: Roles of inflammation and apoptosis.
    Life sciences, 2021, Jan-01, Volume: 264

    Topics: Animals; Apoptosis; Azoxymethane; Carcinogenesis; Cell Count; Cell Line, Tumor; Collagen; Colonic Neoplasms; Dextran Sulfate; Indomethacin; Inflammation; Male; Mast Cells; Mice, Inbred BALB C; Naphthoquinones

2021
The Glucocorticoid Receptor in Intestinal Epithelial Cells Alleviates Colitis and Associated Colorectal Cancer in Mice.
    Cellular and molecular gastroenterology and hepatology, 2021, Volume: 11, Issue:5

    Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colitis-Associated Neoplasms; Dextran Sulfate; Female; Gene Expression Profiling; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Knockout; Permeability; Receptors, Glucocorticoid

2021
Inducible mouse models of colon cancer for the analysis of sporadic and inflammation-driven tumor progression and lymph node metastasis.
    Nature protocols, 2021, Volume: 16, Issue:1

    Topics: Animals; Azoxymethane; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Progression; Female; Inflammation; Lymphatic Metastasis; Male; Mice; Mice, Inbred C57BL

2021
Vitamin E delta-tocotrienol and metabolite 13'-carboxychromanol inhibit colitis-associated colon tumorigenesis and modulate gut microbiota in mice.
    The Journal of nutritional biochemistry, 2021, Volume: 89

    Topics: Animals; Antineoplastic Agents; Azoxymethane; Benzopyrans; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Fatty Acids; Feces; Gastrointestinal Microbiome; Humans; Inflammation; Interleukin-1beta; Male; Mice; Mice, Inbred BALB C; RNA, Ribosomal, 16S; Vitamin E

2021
Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis.
    Scientific reports, 2021, 01-12, Volume: 11, Issue:1

    Topics: Acrolein; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred A; RNA-Binding Proteins

2021
Glutathione transferase Omega 1 confers protection against azoxymethane-induced colorectal tumour formation.
    Carcinogenesis, 2021, 06-21, Volume: 42, Issue:6

    Topics: Animals; Azoxymethane; Carcinogens; Carrier Proteins; Colitis; Colorectal Neoplasms; Dextran Sulfate; Glutathione Transferase; Inflammation; Interleukin-18; Interleukin-1beta; Mice; Mice, Inbred C57BL; Mice, Knockout

2021
Glycyrrhizin Attenuates Carcinogenesis by Inhibiting the Inflammatory Response in a Murine Model of Colorectal Cancer.
    International journal of molecular sciences, 2021, Mar-05, Volume: 22, Issue:5

    Topics: Animals; Azoxymethane; Carcinogenesis; Colon; Colorectal Neoplasms; Disease Models, Animal; Female; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Interleukin-6; Mice; Mice, Inbred ICR; NF-kappa B; Signal Transduction; Tumor Necrosis Factor-alpha

2021
Inhibitory effects of a selective prostaglandin E2 receptor antagonist RQ-15986 on inflammation-related colon tumorigenesis in APC-mutant rats.
    PloS one, 2021, Volume: 16, Issue:5

    Topics: Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; Benzamides; Carcinogenesis; Cell Proliferation; Chemokine CCL2; Colonic Neoplasms; Dextran Sulfate; Dinoprostone; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Interleukin-18; Interleukin-6; Mutation; Rats; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Tumor Necrosis Factor-alpha

2021
Limonin modulated immune and inflammatory responses to suppress colorectal adenocarcinoma in mice model.
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:9

    Topics: Adenocarcinoma; Animals; Antioxidants; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Limonins; Male; Mice; Mice, Inbred BALB C; Oxidative Stress

2021
Chemoprotective Effects of Geraniin against Azoxymethane Induced Colorectal Cancer by Reduction of Inflammatory Reaction.
    Journal of oleo science, 2021, Volume: 70, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Azoxymethane; Body Weight; Colorectal Neoplasms; Cytokines; Enzymes; Female; Glucosides; Hydrolyzable Tannins; Inflammation; Male; Oxidative Stress; Rats, Wistar

2021
Ganoderma lucidum polysaccharide modulates gut microbiota and immune cell function to inhibit inflammation and tumorigenesis in colon.
    Carbohydrate polymers, 2021, Sep-01, Volume: 267

    Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Dysbiosis; Fungal Polysaccharides; Gastrointestinal Microbiome; Humans; Inflammation; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; RAW 264.7 Cells; Reishi; Signal Transduction

2021
Overproduction of Gastrointestinal 5-HT Promotes Colitis-Associated Colorectal Cancer Progression via Enhancing NLRP3 Inflammasome Activation.
    Cancer immunology research, 2021, Volume: 9, Issue:9

    Topics: Animals; Azoxymethane; Cell Line, Tumor; Colitis-Associated Neoplasms; Dextran Sulfate; Gastrointestinal Tract; Humans; Inflammasomes; Inflammation; Interleukin-1beta; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Serotonin; Signal Transduction; Tryptophan Hydroxylase

2021
Anti-Obesity Drug Orlistat Alleviates Western-Diet-Driven Colitis-Associated Colon Cancer via Inhibition of STAT3 and NF-κB-Mediated Signaling.
    Cells, 2021, 08-11, Volume: 10, Issue:8

    Topics: Animals; Anti-Obesity Agents; Antineoplastic Agents; Azoxymethane; Colitis-Associated Neoplasms; Dextran Sulfate; Diet, Western; Inflammation; Mice; NF-kappa B; Orlistat; Signal Transduction; STAT3 Transcription Factor; Transcription Factor RelA

2021
Lack of STAT6 Attenuates Inflammation and Drives Protection against Early Steps of Colitis-Associated Colon Cancer.
    Cancer immunology research, 2017, Volume: 5, Issue:5

    Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Cell Proliferation; Colitis; Colon; Colonic Neoplasms; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Female; Inflammation; Mice, Inbred BALB C; Mice, Knockout; RNA, Messenger; STAT6 Transcription Factor

2017
Clostridium butyricum partially regulates the development of colitis-associated cancer through miR-200c.
    Cellular and molecular biology (Noisy-le-Grand, France), 2017, Apr-29, Volume: 63, Issue:4

    Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Clostridium butyricum; Colitis; Colonic Neoplasms; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization, Fluorescence; Inflammation; Interleukin-12; Mice; MicroRNAs; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha

2017
Inhibition of MK2 suppresses IL-1β, IL-6, and TNF-α-dependent colorectal cancer growth.
    International journal of cancer, 2018, 04-15, Volume: 142, Issue:8

    Topics: Animals; Azoxymethane; Cell Line, Tumor; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Female; Inflammation; Interleukin-1beta; Interleukin-6; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Protein Serine-Threonine Kinases; Signal Transduction; Tumor Necrosis Factor-alpha

2018
Methylglyoxal displays colorectal cancer-promoting properties in the murine models of azoxymethane and CT26 isografts.
    Free radical biology & medicine, 2018, 02-01, Volume: 115

    Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Cell Line; Cholesterol, LDL; Colorectal Neoplasms; Disease Models, Animal; Humans; Inflammation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Oxidative Stress; Precancerous Conditions; Pyruvaldehyde; Transplantation, Isogeneic

2018
Elevated d-2-hydroxyglutarate during colitis drives progression to colorectal cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 01-30, Volume: 115, Issue:5

    Topics: Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Biopsy; Caco-2 Cells; Cell Movement; Cell Proliferation; Cell Survival; Colitis; Colitis, Ulcerative; Colorectal Neoplasms; Dextran Sulfate; Disease Progression; Glutarates; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Intestinal Mucosa; Mice; Risk

2018
Chemopreventive Effect of Aster glehni on Inflammation-Induced Colorectal Carcinogenesis in Mice.
    Nutrients, 2018, Feb-12, Volume: 10, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Aster Plant; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dextran Sulfate; Inflammation; Interleukins; Male; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Spleen; Tumor Necrosis Factor-alpha

2018
Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors.
    International journal of cancer, 2018, 08-15, Volume: 143, Issue:4

    Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colitis; Colonic Neoplasms; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dextran Sulfate; Disease Progression; Epigenesis, Genetic; Histone Deacetylases; Homeostasis; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Neutrophils; Receptors, G-Protein-Coupled

2018
DNA methylome and transcriptome alterations and cancer prevention by curcumin in colitis-accelerated colon cancer in mice.
    Carcinogenesis, 2018, 05-03, Volume: 39, Issue:5

    Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Curcumin; Dextran Sulfate; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Inflammation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Transcriptome

2018
Tea Polysaccharides Inhibit Colitis-Associated Colorectal Cancer via Interleukin-6/STAT3 Pathway.
    Journal of agricultural and food chemistry, 2018, May-02, Volume: 66, Issue:17

    Topics: Animals; Antineoplastic Agents, Phytogenic; Azoxymethane; Camellia sinensis; Cell Line, Tumor; Colitis; Colorectal Neoplasms; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Inflammation; Interleukin-6; Macrophages; Mice; Mice, Inbred BALB C; Polysaccharides; RAW 264.7 Cells; Signal Transduction; STAT3 Transcription Factor; Tea

2018
Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
    Cancer research, 2018, 08-01, Volume: 78, Issue:15

    Topics: Animals; Azoxymethane; Carcinogenesis; Colitis, Ulcerative; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Inflammation; Macrophage Activation; Macrophages; Male; Mice; Ornithine Decarboxylase; Transcription, Genetic; Up-Regulation

2018
The Rac1 splice form Rac1b favors mouse colonic mucosa regeneration and contributes to intestinal cancer progression.
    Oncogene, 2018, Volume: 37, Issue:46

    Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Progression; Epithelial Cells; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Neuropeptides; rac1 GTP-Binding Protein; Signal Transduction

2018
DNA damage response genes mark the early transition from colitis to neoplasia in colitis-associated colon cancer.
    Gene, 2018, Nov-30, Volume: 677

    Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Progression; DNA Damage; Gene Expression Regulation; Inflammation; Inflammatory Bowel Diseases; Intestines; Male; Mice; Mice, Inbred C57BL; Microsatellite Instability; Signal Transduction

2018
The phosphatidic acid phosphatase lipin-1 facilitates inflammation-driven colon carcinogenesis.
    JCI insight, 2018, 09-20, Volume: 3, Issue:18

    Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Chemokine CXCL1; Chemokine CXCL2; Colitis; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Humans; Inflammation; Inflammatory Bowel Diseases; Interleukin-23; Macrophages; Mice; Mice, Inbred BALB C; Mucous Membrane; Nuclear Proteins; Phosphatidate Phosphatase

2018
Effects of 17β-Estradiol on Colonic Permeability and Inflammation in an Azoxymethane/Dextran Sulfate Sodium-Induced Colitis Mouse Model.
    Gut and liver, 2018, 11-15, Volume: 12, Issue:6

    Topics: Animals; Azoxymethane; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Estradiol; Inflammation; Intestinal Mucosa; Kruppel-Like Factor 4; Male; Mice; Mucin-2; Permeability; Signal Transduction; Tight Junctions

2018
Tucum-do-cerrado (Bactris setosa Mart.) modulates oxidative stress, inflammation, and apoptosis-related proteins in rats treated with azoxymethane.
    PloS one, 2018, Volume: 13, Issue:11

    Topics: Animals; Apoptosis; Arecaceae; Azoxymethane; Colon; Colonic Neoplasms; Disease Models, Animal; Fruit; Inflammation; Liver; Male; Oxidative Stress; Phytotherapy; Rats, Wistar

2018
Effects of obesity and exercise on colon cancer induction and hematopoiesis in mice.
    American journal of physiology. Endocrinology and metabolism, 2019, 02-01, Volume: 316, Issue:2

    Topics: Adipose Tissue; Animals; Azoxymethane; Bone Marrow; Carcinogens; Colonic Neoplasms; Diet, High-Fat; Hematopoiesis; Hematopoietic Stem Cells; Inflammation; Mice; Myeloid Progenitor Cells; Neoplasms, Experimental; Obesity; Physical Conditioning, Animal; Proteomics; Random Allocation; Sedentary Behavior

2019
Intermittent hypoxia promotes carcinogenesis in azoxymethane and dextran sodium sulfate-induced colon cancer model.
    Molecular carcinogenesis, 2019, Volume: 58, Issue:5

    Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Hypoxia; Inflammation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress

2019
The Azoxymethane/Il10
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1960

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Disease Models, Animal; Germ-Free Life; Inflammation; Inflammatory Bowel Diseases; Interleukin-10; Intestines; Mice, Knockout

2019
Impact of 5 fluorouracil chemotherapy on gut inflammation, functional parameters, and gut microbiota.
    Brain, behavior, and immunity, 2019, Volume: 80

    Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Fecal Microbiota Transplantation; Fluorouracil; Gastrointestinal Microbiome; Inflammation; Male; Mice; Mice, Inbred C57BL

2019
Elevated circulating TGFβ1 during acute liver failure activates TGFβR2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice.
    Journal of neuroinflammation, 2019, Apr-02, Volume: 16, Issue:1

    Topics: Animals; Antibodies; Azoxymethane; Benzamides; Carcinogens; Cell Line, Transformed; Cerebral Cortex; Disease Models, Animal; Hepatic Encephalopathy; Inflammation; Isoquinolines; Liver; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neurons; Phagocytosis; Pyrazoles; Pyridines; Pyrroles; Receptor, Transforming Growth Factor-beta Type II; Signal Transduction; Transforming Growth Factor beta1; Up-Regulation

2019
Ay allele promotes azoxymethane-induced colorectal carcinogenesis by macrophage migration in hyperlipidemic/diabetic KK mice.
    Cancer science, 2013, Volume: 104, Issue:7

    Topics: Alleles; Animals; Azoxymethane; beta Catenin; Carcinogenesis; Cell Movement; Cocarcinogenesis; Colorectal Neoplasms; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Hyperlipidemias; Inflammation; Insulin; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Inbred NOD; RNA, Messenger; Triglycerides

2013
Colitis-accelerated colorectal cancer and metabolic dysregulation in a mouse model.
    Carcinogenesis, 2013, Volume: 34, Issue:8

    Topics: Animals; Apoptosis; Azoxymethane; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Inflammation; Metabolic Diseases; Mice; Mice, Inbred BALB C; MicroRNAs; RNA, Messenger; Transcriptome; Up-Regulation; Wnt Proteins

2013
Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation.
    Cancer prevention research (Philadelphia, Pa.), 2013, Volume: 6, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Azoxymethane; beta Catenin; Biomarkers, Tumor; Blotting, Western; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Cytokines; Extracellular Signal-Regulated MAP Kinases; Gene Expression Profiling; Grape Seed Extract; Immunoenzyme Techniques; Inflammation; Male; Mice; Mice, Inbred A; MicroRNAs; Mitogen-Activated Protein Kinases; NF-kappa B; Oligonucleotide Array Sequence Analysis; Phosphorylation; Signal Transduction

2013
A novel shift in estrogen receptor expression occurs as estradiol suppresses inflammation-associated colon tumor formation.
    Endocrine-related cancer, 2013, Volume: 20, Issue:4

    Topics: Animals; Antineoplastic Agents; Azoxymethane; Colonic Neoplasms; Dextran Sulfate; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout

2013
Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Azoxymethane; Carcinogenesis; Colitis; Colonic Neoplasms; Deoxyguanosine; Dextran Sulfate; Diet; DNA Damage; Epidermal Growth Factor; Gene Expression Regulation; Inflammation; Mice; Mice, Inbred C57BL; Selenium; Signal Transduction; Transforming Growth Factor beta; Weight Loss

2013
Lipopolysaccharide precipitates hepatic encephalopathy and increases blood-brain barrier permeability in mice with acute liver failure.
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34, Issue:3

    Topics: Ammonia; Animals; Azoxymethane; Blood-Brain Barrier; Cytokines; Disease Models, Animal; Hepatic Encephalopathy; Inflammation; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Permeability; Transaminases

2014
Pomegranate polyphenolics suppressed azoxymethane-induced colorectal aberrant crypt foci and inflammation: possible role of miR-126/VCAM-1 and miR-126/PI3K/AKT/mTOR.
    Carcinogenesis, 2013, Volume: 34, Issue:12

    Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Beverages; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; HT29 Cells; Humans; Inflammation; Lythraceae; Male; MicroRNAs; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinase; Polyphenols; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases; Vascular Cell Adhesion Molecule-1

2013
The importance of the retinoid X receptor alpha in modulating inflammatory signaling in acute murine colitis.
    Digestive diseases and sciences, 2014, Volume: 59, Issue:4

    Topics: Animals; Azoxymethane; Carcinogens; Colitis; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Heterozygote; Immunoblotting; Inflammation; Mice; Receptors, Calcitriol; Retinoid X Receptor alpha

2014
Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer.
    Gastroenterology, 2014, Volume: 147, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Azoxymethane; Biopsy; Case-Control Studies; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Inflammation; Inflammatory Bowel Diseases; Mice; Mice, Knockout; NF-kappa B; Polymorphism, Single Nucleotide; RNA, Messenger

2014
Dynamic microbe and molecule networks in a mouse model of colitis-associated colorectal cancer.
    Scientific reports, 2014, May-15, Volume: 4

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Tract; Inflammation; Male; Mice; Mice, Inbred BALB C; RNA, Ribosomal, 16S

2014
Nuclear adenomatous polyposis coli suppresses colitis-associated tumorigenesis in mice.
    Carcinogenesis, 2014, Volume: 35, Issue:8

    Topics: Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Azoxymethane; beta Catenin; Blotting, Western; Carcinogens; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Disease Models, Animal; Inflammation; Mice; Mutation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction

2014
Combinational chemoprevention effect of celecoxib and an oral antiangiogenic LHD4 on colorectal carcinogenesis in mice.
    Anti-cancer drugs, 2014, Volume: 25, Issue:9

    Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Celecoxib; Colon; Colonic Polyps; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Deoxycholic Acid; Dextran Sulfate; Drug Therapy, Combination; Heparin, Low-Molecular-Weight; Inflammation; Male; Mice, Inbred ICR; Neovascularization, Pathologic; Pyrazoles; Sulfonamides; Tumor Burden

2014
Bovine milk-derived α-lactalbumin inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sodium sulfate-treated mice.
    Bioscience, biotechnology, and biochemistry, 2014, Volume: 78, Issue:4

    Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Carcinogenesis; Cattle; Colon; Colonic Neoplasms; Dextran Sulfate; Dietary Supplements; Dinoprostone; Inflammation; Interleukin-1beta; Lactalbumin; Male; Mice; Mice, Inbred C57BL; Milk; Occult Blood; Organ Size; Tumor Necrosis Factor-alpha

2014
Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Animals; Apoptosis; Azoxymethane; Cell Proliferation; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Gene Knockout Techniques; Humans; Inflammation; Lactoferrin; Male; Mice; NF-kappa B; Signal Transduction

2014
[Inflammation promotes the development of colitis-associated colorectal cancer].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2014, Volume: 17, Issue:7

    Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Immunohistochemistry; Inflammation; Interleukin-6; Mice; Mice, Inbred C57BL; Signal Transduction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha

2014
Sulindac reversal of 15-PGDH-mediated resistance to colon tumor chemoprevention with NSAIDs.
    Carcinogenesis, 2015, Volume: 36, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Azoxymethane; Carcinogens; Celecoxib; Chemoprevention; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Hydroxyprostaglandin Dehydrogenases; Inflammation; Intestinal Mucosa; Membrane Proteins; Mice; Mice, Knockout; Pyrazoles; Sulfonamides; Sulindac

2015
Protective Effects of Turbinaria ornata and Padina pavonia against Azoxymethane-Induced Colon Carcinogenesis through Modulation of PPAR Gamma, NF-κB and Oxidative Stress.
    Phytotherapy research : PTR, 2015, Volume: 29, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Colonic Neoplasms; Glutathione; Glutathione Peroxidase; Humans; Inflammation; Lipid Peroxidation; Male; Malondialdehyde; Mice; NF-kappa B; Nitric Oxide; Oxidative Stress; Phaeophyceae; PPAR gamma; Seaweed; Superoxide Dismutase; Tumor Suppressor Protein p53

2015
NF-κB1, NF-κB2 and c-Rel differentially regulate susceptibility to colitis-associated adenoma development in C57BL/6 mice.
    The Journal of pathology, 2015, Volume: 236, Issue:3

    Topics: Adenoma; Animals; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Disease Susceptibility; Epithelial Cells; Female; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B p50 Subunit; NF-kappa B p52 Subunit; Proto-Oncogene Proteins c-rel; Signal Transduction

2015
T-cells enhance stem cell mutagenesis in the mouse colon.
    Mutation research, 2015, Volume: 774

    Topics: Animals; Azoxymethane; Colon; Colonic Neoplasms; Dextran Sulfate; DNA Damage; Drug Synergism; Guanine; Inflammation; Male; Mice, Inbred C57BL; Mice, Knockout; Mutagenesis; Receptors, Antigen, T-Cell, alpha-beta; Stem Cells; T-Lymphocytes

2015
SPINK1 Status in Colorectal Cancer, Impact on Proliferation, and Role in Colitis-Associated Cancer.
    Molecular cancer research : MCR, 2015, Volume: 13, Issue:7

    Topics: Aged; Animals; Azoxymethane; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Colitis; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Glycoproteins; Humans; Inflammation; Japan; Male; Mice, Inbred C57BL; Middle Aged; Prostatic Secretory Proteins; Trypsin Inhibitor, Kazal Pancreatic

2015
Mesenchymal stem cells-regulated Treg cells suppress colitis-associated colorectal cancer.
    Stem cell research & therapy, 2015, Apr-13, Volume: 6

    Topics: Animals; Azoxymethane; CD4 Lymphocyte Count; Cell Differentiation; Cell Line; Cell Movement; Cell- and Tissue-Based Therapy; Colitis; Colon; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Humans; Inflammation; Jurkat Cells; Lymphocyte Activation; Lymphocyte Count; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Signal Transduction; Smad2 Protein; T-Lymphocytes, Regulatory; Th17 Cells; Th2 Cells; Umbilical Cord

2015
Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis.
    Nature communications, 2015, Apr-24, Volume: 6

    Topics: Adenocarcinoma; Animals; Azoxymethane; Bacteroides fragilis; Blotting, Western; Carcinogenesis; Carcinogens; Cell Line, Tumor; Cell Proliferation; Chemokine CCL20; Colitis; Colonic Neoplasms; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Enterobacteriaceae; Exosomes; Immunohistochemistry; In Situ Hybridization, Fluorescence; Inflammation; Intestinal Mucosa; Lysophospholipids; Mice; Myeloid Differentiation Factor 88; Nanoparticles; Neoplasm Transplantation; Reverse Transcriptase Polymerase Chain Reaction; Sphingosine; Th17 Cells

2015
IL-32α suppresses colorectal cancer development via TNFR1-mediated death signaling.
    Oncotarget, 2015, Apr-20, Volume: 6, Issue:11

    Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; Enzyme Activation; Humans; Inflammation; Interleukins; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Transgenic; Neoplasm Proteins; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins; Signal Transduction

2015
Development of an oral nanotherapeutics using redox nanoparticles for treatment of colitis-associated colon cancer.
    Biomaterials, 2015, Volume: 55

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Azoxymethane; Camptothecin; Cell Line, Tumor; Colitis; Colonic Neoplasms; Dextrans; Drug Delivery Systems; Drug Screening Assays, Antitumor; Endoscopy; Free Radical Scavengers; Inflammation; Irinotecan; Male; Mice; Mice, Inbred ICR; Nanomedicine; Nanoparticles; Neoplasms, Experimental; Nitrogen Oxides; Oxidation-Reduction; Reactive Oxygen Species; Sulfates

2015
St. John's Wort Attenuates Colorectal Carcinogenesis in Mice through Suppression of Inflammatory Signaling.
    Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; Diet; Dietary Supplements; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Hypericum; Inflammation; Male; Mice; NF-kappa B; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Plant Extracts; Signal Transduction

2015
Calpain-2 Inhibitor Therapy Reduces Murine Colitis and Colitis-associated Cancer.
    Inflammatory bowel diseases, 2015, Volume: 21, Issue:9

    Topics: Animals; Azoxymethane; Cell Proliferation; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; HT29 Cells; Humans; I-kappa B Proteins; Inflammation; Injections, Intraperitoneal; Macrophage Activation; Mice; NF-kappa B; Oligopeptides; Translocation, Genetic

2015
Ghrelin administration suppresses inflammation-associated colorectal carcinogenesis in mice.
    Cancer science, 2015, Volume: 106, Issue:9

    Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Ghrelin; Inflammation; Male; Mice; Mice, Inbred C57BL

2015
PAK1 promotes intestinal tumor initiation.
    Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:11

    Topics: Animals; Azoxymethane; beta Catenin; Carcinogenesis; Colonoscopy; Dextrans; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Genotype; Heterozygote; Immunohistochemistry; Inflammation; Intestinal Neoplasms; Male; Mesalamine; Mice; Mice, Inbred C57BL; Mice, Knockout; p21-Activated Kinases; Signal Transduction

2015
Thrombospondin-1 in a Murine Model of Colorectal Carcinogenesis.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Immunohistochemistry; Inflammation; Mice, Inbred C57BL; Microvessels; Reproducibility of Results; RNA, Messenger; Thrombospondin 1; Up-Regulation

2015
Dead Nano-Sized Lactobacillus plantarum Inhibits Azoxymethane/Dextran Sulfate Sodium-Induced Colon Cancer in Balb/c Mice.
    Journal of medicinal food, 2015, Volume: 18, Issue:12

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogenesis; Cell Cycle Checkpoints; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Immunoglobulin A; Inflammation; Lactobacillus plantarum; Mice, Inbred BALB C; Particle Size

2015
Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation.
    BMC cancer, 2016, Mar-07, Volume: 16

    Topics: Animals; Azoxymethane; Biomarkers, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chemokines; Colonic Neoplasms; Cytokines; Dextran Sulfate; Ethanol; Female; Gene Expression; Inflammation; Intestinal Mucosa; Mice; Protein Transport

2016
The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury.
    Oncotarget, 2016, May-10, Volume: 7, Issue:19

    Topics: Animals; Apoptosis; Azoxymethane; Colon; Colonic Neoplasms; Dextran Sulfate; DNA Glycosylases; Endodeoxyribonucleases; Humans; Inflammation; Intestinal Mucosa; Kaplan-Meier Estimate; Mice, Knockout; Tumor Burden

2016
Unpolished Thai Rice Prevents Aberrant Crypt Foci Formation through the Invovement of ?catenin and COX2 Expression in AzoxymethaneTreated Rats.
    Asian Pacific journal of cancer prevention : APJCP, 2016, Volume: 17, Issue:7

    Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Biomarkers; Catenins; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase 2; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-6; Male; Oryza; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Thailand

2016
Protective effects of Huangqin Decoction against ulcerative colitis and associated cancer in mice.
    Oncotarget, 2016, Sep-20, Volume: 7, Issue:38

    Topics: Animals; Antioxidants; Azoxymethane; Chromatography, High Pressure Liquid; Colitis, Ulcerative; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Drugs, Chinese Herbal; Flavanones; Inflammation; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Oxidative Stress; Plant Extracts; Scutellaria baicalensis

2016
Anti-inflammatory natural product goniothalamin reduces colitis-associated and sporadic colorectal tumorigenesis.
    Carcinogenesis, 2017, Volume: 38, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Azoxymethane; Biological Products; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Inflammation; Inflammation Mediators; Macrophages; Mice; Mice, Inbred C57BL; Pyrones

2017
Repression of MicroRNA Function Mediates Inflammation-associated Colon Tumorigenesis.
    Gastroenterology, 2017, Volume: 152, Issue:3

    Topics: Animals; Azoxymethane; Caco-2 Cells; Carcinogenesis; Carcinoma; Cell Line, Tumor; Colitis; Colon; Colonic Neoplasms; Cytidine Deaminase; Cytokines; DEAD-box RNA Helicases; Dextran Sulfate; Fibroblasts; Flow Cytometry; HCT116 Cells; HT29 Cells; Humans; Immunoblotting; Immunohistochemistry; Inflammation; Interleukin-1alpha; Interleukin-1beta; Mice; MicroRNAs; Ribonuclease III; Tumor Necrosis Factor-alpha

2017
Cilostazol and enzymatically modified isoquercitrin attenuate experimental colitis and colon cancer in mice by inhibiting cell proliferation and inflammation.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 100

    Topics: Animals; Azoxymethane; Carcinogens; Cell Proliferation; Cilostazol; Colitis; Colonic Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; Immunohistochemistry; Inflammation; Mice; Mice, Inbred BALB C; Organ Size; Quercetin; Tetrazoles; Vasodilator Agents

2017
Role for sphingosine kinase 1 in colon carcinogenesis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2009, Volume: 23, Issue:2

    Topics: Animals; Azoxymethane; Cell Transformation, Neoplastic; Colonic Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Lysophospholipids; Mice; Mice, Knockout; Phosphotransferases (Alcohol Group Acceptor); Sphingosine

2009
Inflammation-associated serum and colon markers as indicators of dietary attenuation of colon carcinogenesis in ob/ob mice.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:1

    Topics: Animals; Azoxymethane; Biomarkers, Tumor; Carcinogens; Colonic Neoplasms; Cytokines; Diet; Fabaceae; Gene Expression; Inflammation; Interleukin-6; Male; Mice; Mice, Obese; Obesity; Phytotherapy; Plant Extracts; Precancerous Conditions; Reverse Transcriptase Polymerase Chain Reaction

2009
A gamma-tocopherol-rich mixture of tocopherols inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sulfate sodium-treated mice.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Antioxidants; Apoptosis; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Colon; Colonic Neoplasms; Dextran Sulfate; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; gamma-Tocopherol; Inflammation; Leukotriene B4; Male; Mice; Tyrosine

2009
Mucin-depleted foci show strong activation of inflammatory markers in 1,2-dimethylhydrazine-induced carcinogenesis and are promoted by the inflammatory agent sodium dextran sulfate.
    International journal of cancer, 2009, Aug-01, Volume: 125, Issue:3

    Topics: 1,2-Dimethylhydrazine; Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Inflammation; Male; Mucin-2; Nitric Oxide Synthase Type II; Precancerous Conditions; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation

2009
Epithelial vanin-1 controls inflammation-driven carcinogenesis in the colitis-associated colon cancer model.
    Inflammatory bowel diseases, 2010, Volume: 16, Issue:1

    Topics: Amidohydrolases; Animals; Azoxymethane; Blotting, Western; Carcinogens; Cell Adhesion Molecules; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Epithelial Cells; Female; Fluorescent Antibody Technique; GPI-Linked Proteins; Inflammation; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2010
Dietary tricin suppresses inflammation-related colon carcinogenesis in male Crj: CD-1 mice.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:12

    Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Blotting, Western; Carcinogens; Colonic Neoplasms; Diet; Flavonoids; Inflammation; Male; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2009
Bifidobacterium lactis inhibits NF-kappaB in intestinal epithelial cells and prevents acute colitis and colitis-associated colon cancer in mice.
    Inflammatory bowel diseases, 2010, Volume: 16, Issue:9

    Topics: Acute Disease; Animals; Azoxymethane; Bifidobacteriales Infections; Bifidobacterium; Blotting, Western; Carcinogens; Chronic Disease; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Immunoenzyme Techniques; Inflammation; Intestinal Mucosa; Lipopolysaccharides; Luciferases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2010
Pitavastatin inhibits azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db obese mice.
    Cancer science, 2010, Volume: 101, Issue:7

    Topics: Animals; Azoxymethane; Carcinogens; Cell Division; Colonic Neoplasms; Cytokines; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Precancerous Conditions; Quinolines

2010
N-acetylcysteine attenuates cerebral complications of non-acetaminophen-induced acute liver failure in mice: antioxidant and anti-inflammatory mechanisms.
    Metabolic brain disease, 2010, Volume: 25, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Azoxymethane; Brain Edema; Carcinogens; Cytokines; Disease Models, Animal; Hepatic Encephalopathy; Inflammation; Inflammation Mediators; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Oxidative Stress

2010
Epimorphin deletion protects mice from inflammation-induced colon carcinogenesis and alters stem cell niche myofibroblast secretion.
    The Journal of clinical investigation, 2010, Volume: 120, Issue:6

    Topics: Animals; Azoxymethane; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Epithelial Cells; Inflammation; Interleukin-6; Intestinal Mucosa; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; Sequence Deletion

2010
Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis-associated tumorigenesis.
    Inflammatory bowel diseases, 2011, Volume: 17, Issue:7

    Topics: Animals; Azoxymethane; Blotting, Western; Carcinogens; Colitis, Ulcerative; Colonic Neoplasms; Dextran Sulfate; Enzyme-Linked Immunosorbent Assay; Humans; Immunoenzyme Techniques; Inflammation; Inflammation Mediators; Intestinal Mucosa; Mice; Mice, Transgenic; Microfilament Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Toll-Like Receptor 4

2011
Prevention of colitis-associated colorectal cancer with 8-hydroxydeoxyguanosine.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticarcinogenic Agents; Azoxymethane; Colitis; Colorectal Neoplasms; Deoxyguanosine; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation; Interleukin-10; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms; STAT3 Transcription Factor; Sulfates

2011
Chronic psychosocial stress increases the risk for inflammation-related colon carcinogenesis in male mice.
    Stress (Amsterdam, Netherlands), 2012, Volume: 15, Issue:4

    Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Housing, Animal; Inflammation; Interferon-gamma; Male; Mice; Mice, Inbred C57BL; Social Dominance; Stress, Psychological

2012
Effects of S-adenosylmethionine and methylthioadenosine on inflammation-induced colon cancer in mice.
    Carcinogenesis, 2012, Volume: 33, Issue:2

    Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Colonic Neoplasms; Dextran Sulfate; Inflammation; Interleukin-10; Interleukin-6; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-akt; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; STAT3 Transcription Factor; Transcriptional Activation; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2012
Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply.
    Carcinogenesis, 2012, Volume: 33, Issue:3

    Topics: Animals; Apoptosis; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Glutathione Peroxidase; Glutathione Transferase; Ileum; Inflammation; Isothiocyanates; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Selenium; Sulfoxides; Thiocyanates; Thioredoxin-Disulfide Reductase

2012
Optical imaging of MMP expression and cancer progression in an inflammation-induced colon cancer model.
    International journal of cancer, 2012, Oct-15, Volume: 131, Issue:8

    Topics: Animals; Azoxymethane; beta Catenin; Blotting, Western; Carbocyanines; Carcinogens; Colonic Neoplasms; Dextran Sulfate; Diagnostic Imaging; Disease Models, Animal; Disease Progression; Immunoenzyme Techniques; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Peptide Fragments

2012
Glucagon-like peptide-2 increases dysplasia in rodent models of colon cancer.
    American journal of physiology. Gastrointestinal and liver physiology, 2012, Apr-15, Volume: 302, Issue:8

    Topics: Animals; Azoxymethane; beta Catenin; Blotting, Western; Carcinogens; Colitis; Colonic Neoplasms; Dextran Sulfate; Diet, High-Fat; Doublecortin Protein; Glucagon-Like Peptide 2; Imidazoles; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Inbred F344; Real-Time Polymerase Chain Reaction; RNA, Messenger

2012
Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammation.
    The Journal of experimental medicine, 2012, Jul-02, Volume: 209, Issue:7

    Topics: Animals; Azoxymethane; Carcinogens; Chromosome Mapping; Chromosomes, Mammalian; Colitis; Colorectal Neoplasms; Disease Resistance; Genetic Loci; Genetic Predisposition to Disease; Helicobacter hepaticus; Helicobacter Infections; Host-Pathogen Interactions; Humans; Immunity, Innate; Inflammation; Mice; Mice, 129 Strain; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Polymorphism, Single Nucleotide; Telomere

2012
Dietary folate does not significantly affect the intestinal microbiome, inflammation or tumorigenesis in azoxymethane-dextran sodium sulphate-treated mice.
    The British journal of nutrition, 2013, Feb-28, Volume: 109, Issue:4

    Topics: Animals; Azoxymethane; Biomarkers; Colitis, Ulcerative; Colon; Colonic Neoplasms; Dextran Sulfate; Dextrans; Diet; Disease Progression; Folic Acid; Inflammation; Male; Mice; Mice, Inbred C57BL; Microbiota; Neoplasms; RNA, Ribosomal, 16S; Sulfates

2013
Organomagnesium suppresses inflammation-associated colon carcinogenesis in male Crj: CD-1 mice.
    Carcinogenesis, 2013, Volume: 34, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Apoptosis; Azoxymethane; Blotting, Western; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Humans; Immunoenzyme Techniques; Inflammation; Interferon-gamma; Interleukin-1beta; Interleukin-6; Magnesium Compounds; Male; Mice; Mice, Inbred ICR; Mitotic Index; Organometallic Compounds; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2013
Cocoa polyphenols prevent inflammation in the colon of azoxymethane-treated rats and in TNF-α-stimulated Caco-2 cells.
    The British journal of nutrition, 2013, Jul-28, Volume: 110, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Azoxymethane; Biomarkers; Cacao; Colon; Diet; Down-Regulation; Humans; Inflammation; Inflammation Mediators; Male; MAP Kinase Kinase 4; Neoplasms; NF-kappa B; Phosphorylation; Phytotherapy; Plant Extracts; Polyphenols; Rats; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha

2013
A polyacetylene-rich extract from Gymnaster koraiensis strongly inhibits colitis-associated colon cancer in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 53

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Asteraceae; Azoxymethane; Cell Proliferation; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Inflammation; Liver; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Polyynes

2013
Hesperidin alleviates oxidative stress and downregulates the expressions of proliferative and inflammatory markers in azoxymethane-induced experimental colon carcinogenesis in mice.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2013, Volume: 62, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Azoxymethane; Biomarkers; Carcinogens; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Down-Regulation; Hesperidin; Inflammation; Male; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Proliferating Cell Nuclear Antigen

2013
A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate.
    Cancer science, 2003, Volume: 94, Issue:11

    Topics: Adenocarcinoma; Adenoma; Animals; Anticoagulants; Azoxymethane; beta Catenin; Carcinogens; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Dextran Sulfate; Disease Models, Animal; Inflammation; Injections, Intraperitoneal; Isoenzymes; Male; Mast Cells; Mice; Mice, Inbred ICR; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Trans-Activators; Tumor Suppressor Protein p53

2003
Liver receptor homolog 1 contributes to intestinal tumor formation through effects on cell cycle and inflammation.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Feb-08, Volume: 102, Issue:6

    Topics: Animals; Azoxymethane; Carcinogens; Cell Cycle; Disease Models, Animal; Female; Heterozygote; Humans; Inflammation; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Receptors, Cytoplasmic and Nuclear; Tumor Necrosis Factor-alpha

2005
Beta-Catenin mutations in a mouse model of inflammation-related colon carcinogenesis induced by 1,2-dimethylhydrazine and dextran sodium sulfate.
    Cancer science, 2005, Volume: 96, Issue:2

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Azoxymethane; beta Catenin; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Dextran Sulfate; Disease Models, Animal; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred ICR; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Trans-Activators

2005
Polyethylene glycol reduces inflammation and aberrant crypt foci in carcinogen-initiated rats.
    Cancer letters, 2005, Jun-08, Volume: 223, Issue:2

    Topics: Administration, Oral; Animals; Azoxymethane; Caco-2 Cells; Carcinogens; Colon; Colonic Neoplasms; Humans; Inflammation; Male; Permeability; Polyethylene Glycols; Precancerous Conditions; Rats; Rats, Inbred F344; Solvents

2005
Global gene expression analysis of the mouse colonic mucosa treated with azoxymethane and dextran sodium sulfate.
    BMC cancer, 2007, May-17, Volume: 7

    Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression; Gene Expression Profiling; Inflammation; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; Oligonucleotide Array Sequence Analysis

2007
Colon cancer chemoprevention by a novel NO chimera that shows anti-inflammatory and antiproliferative activity in vitro and in vivo.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:8

    Topics: Animals; Apoptosis; Azoxymethane; Cell Count; Cell Line, Tumor; Cell Proliferation; Chemoprevention; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p27; Disulfides; DNA Damage; Enzyme Induction; Flow Cytometry; Humans; Inflammation; Male; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Poly(ADP-ribose) Polymerases; Precancerous Conditions; Rats; Rats, Inbred F344

2007
Cyclooxygenase 2 expression is increased in the stroma of colon carcinomas from IL-10(-/-) mice.
    Gastroenterology, 2000, Volume: 118, Issue:2

    Topics: Animals; Azoxymethane; Colon; Colonic Neoplasms; Cyclooxygenase 2; In Situ Hybridization; Inflammation; Interleukin-10; Intestinal Mucosa; Isoenzymes; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stromal Cells

2000