azoxymethane has been researched along with Inflammation in 130 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 12 (9.23) | 29.6817 |
2010's | 79 (60.77) | 24.3611 |
2020's | 39 (30.00) | 2.80 |
Authors | Studies |
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Donthi, D; Hong, H; Lertpiriyapong, K; Marie, MA; Sanderlin, EJ; Satturwar, S; Yang, LV | 1 |
Chen, GQ; Chen, J; Li, Z; Liu, G; Wu, F; Zhang, S; Zhang, Y | 1 |
Bou-Dargham, M; Chen, YH; Etwebi, Z; Goldsmith, JR; Hood, R; Lengner, C; Li, M; Liu, S; Lou, Y; Spitofsky, N; Sun, H; Tian, Y | 1 |
Deng, J; Han, L; Li, Y; Shi, J; Wang, H; Yan, Y; Yuan, X; Zhang, H; Zhao, H; Zhao, L; Zhao, Y; Zou, F | 1 |
Jiang, S; Ma, F; Mu, G; Qian, F; Song, Y; Sun, M; Tuo, Y; Wang, A | 1 |
Chen, K; Gao, Z; Jia, H; Shi, Y; Wang, Z; Yuan, Y; Yue, T; Zeng, X | 1 |
Dong, S; Ismael, M; Lü, X; Shan, Y; Wang, T; Wang, X; Zheng, J | 1 |
Chen, Y; Diao, T; Li, D; Shang, G; Shi, L; Sun, L; Yin, X | 1 |
Chen, Q; Fu, J; Han, H; Lin, H; Lu, G; Ma, X; Qi, J; Wen, Z; Yang, M; Yang, X; Yang, Y; Yin, T | 1 |
Ajayi, BO; Ajeigbe, OF; Anyebe, DA; Farombi, EO; Maruf, OR; Opafunso, IT | 1 |
Archer, A; Birgersson, M; Hases, L; Indukuri, R; Williams, C | 1 |
Ando, Y; Aoi, M; Fukui, T; Horitani, S; Matsumoto, Y; Naganuma, M; Okazaki, K; Tanaka, H; Tomiyama, T; Tsuneyama, K; Uragami, T | 1 |
Huang, XH; Jiang, B; Ni, M; Wang, L; Xu, YY; Zhang, QQ; Zhang, R; Zhang, YQ; Zhao, Q | 1 |
Fan, RJ; Fang, MD; Ren, J; Tu, LL; Yao, WX; Zhang, YM; Zuo, BW | 1 |
Bullard, BM; Cardaci, TD; Fan, D; Hofseth, LJ; Huss, AR; McDonald, SJ; Murphy, EA; VanderVeen, BN | 1 |
Chung, JH; Hong, GH; Lee, SY; Park, KY | 1 |
Chen, Y; Li, P; Liang, J; Luo, X; Wang, Q; Xie, X; Yang, C; Zhang, M; Zhou, L | 1 |
Beck, S; Crossland, NA; Crott, JW; Guo, W; Lo, M; Mason, JB; Tan, WY; Zhang, C | 1 |
Chen, X; Decker, EA; Kim, D; Ma, Q; Park, Y; Qi, W; Sanidad, KZ; Yang, R; Zhang, G; Zhang, J | 1 |
Chen, X; Han, W; Li, Y; Shi, L; Wan, J; Wang, H; Xie, B | 1 |
Chia, YC; Fu, YS; Lin, SR; Lue, SI; Tsai, MJ; Tseng, FJ; Weng, CF; Woon, M; Zheng, JH | 1 |
Eun, CS; Han, DS; Jo, SV; Lee, AR; Lee, JG; Park, CH | 1 |
Chen, D; Huang, Z; Liu, Y; Ma, H; Ouyang, G; Wang, J; Wu, T; Zhao, X | 1 |
Berhow, M; Gonzalez de Mejia, E; Luna-Vital, D; Mazewski, C | 1 |
Benninghoff, AD; Hintze, KJ; Hunter, AH; Monsanto, SP; Pestka, JJ; Phatak, S; Rodriguez, DM; Ward, RE; Wettere, AJV | 1 |
Crott, JW; Kane, AV; Koh, GY; Wu, X | 1 |
Lin, L; Lin, Y; Qu, S; Wang, D; Zhao, H | 1 |
Akbari, A; Asadollahi, P; Ghanavati, R; Javadi, A; Mohammadi, F; Rohani, M; Talebi, M | 1 |
Alcalde, A; Arias, MA; Bird, PI; Camerer, E; Castro, M; Comas, L; Del Campo, R; Ferrandez, A; Galvez, EM; Garrido, M; Garzón, M; Gil-Gómez, G; Jaime-Sanchez, P; Lanuza, PM; Layunta, E; Martínez-Lostao, L; Metkar, S; Moreno, V; Muñoz, G; Pardo, J; Pelegrín, P; Peña, R; Ramirez-Labrada, A; Santiago, L; Sanz-Pamplona, R; Tapia, E; Uranga, JA; Uranga-Murillo, I | 1 |
Deng, T; Liu, M; Wan, X; Xie, W | 1 |
Devaraj, H; Seetha, A; Sudhandiran, G | 1 |
Bohnenberger, H; Meers, GK; Muzzi, C; Reichardt, HM; Reichardt, SD; Twomey, E; Watanabe, N | 1 |
Boonsanay, V; Brabletz, T; Greten, FR; Heichler, C; Neufert, C; Neurath, MF; Scheibe, K | 1 |
Im, S; Jiang, Q; Jones-Hall, Y; Nakatsu, C; Yang, C; Zhao, Y | 1 |
Epifano, F; Fiorito, S; Genovese, S; Ibuka, T; Ideta, T; Kubota, M; Maruta, A; Miyazaki, T; Mizutani, T; Sakai, H; Shimizu, M; Shirakami, Y; Taddeo, VA; Tanaka, T | 1 |
Board, PG; Casarotto, MG; Dahlstrom, JE; Fernando, N; Hughes, MM; O'Neill, LAJ; Rooke, M; Takahashi, S; Tummala, P | 1 |
Hiramoto, K; Kawanishi, S; Ma, N; Murata, M; Ohnishi, S; Wang, G; Yoshikawa, N | 1 |
Ibuka, T; Ideta, T; Kochi, T; Kubota, M; Nakanishi, T; Ozawa, N; Sakai, H; Shimizu, M; Shirakami, Y; Tanaka, T | 1 |
Esa, NM; Ishak, NIM; Madzuki, IN; Mohamed, S; Mustapha, NM | 1 |
Lei, J; Wei, Y; Zhang, H; Zhou, R | 1 |
Chen, C; Chen, J; Chen, R; Fang, L; Guo, C; Guo, D; Sang, T; Wang, X; Wang, Y; Wu, J | 1 |
Cao, M; Chen, Y; Fu, B; Hu, R; Li, T; Tan, Y; Yang, M; Zhang, X; Zhou, Y | 1 |
An, HJ; Jin, BR; Kim, HJ; Lee, M; Sim, SA | 1 |
Arias-Romero, LE; Ávila-Moreno, F; Chirino, YI; Delgado-Buenrostro, NL; Delgado-Ramirez, YG; Gutierrez-Cirlos, EB; Ledesma-Soto, Y; Leon-Cabrera, SA; Molina-Guzman, E; Pérez-Plasencia, CG; Rodríguez-Sosa, M; Terrazas, LI; Vaca-Paniagua, F; Vázquez-Sandoval, A | 1 |
Dai, X; Gui, G; Li, K; Liu, J; Xiao, Y; Yang, H | 1 |
Berggren, KL; Beswick, EJ; Gan, GN; Ray, AL; Restrepo Cruz, S | 1 |
Lin, JA; Wu, CH; Yen, GC | 1 |
Arning, E; Ashcraft, P; Cook, B; Genta, RM; Han, J; Holm, J; Jackson, D; Souza, RF; Sweetman, L; Theiss, AL; Turner, K; Venuprasad, K; Wang, X | 1 |
An, HJ; Cheon, SY; Chung, KS; Lee, M; Roh, SS | 1 |
Agle, KA; Chen, X; Drobyski, WR; Huang, YW; Oshima, K; Pan, P; Wang, LS; Yearsley, MM; Yu, J; Zhang, J | 1 |
Cheng, D; Fang, M; Gao, L; Gaspar, JM; Guo, Y; Hart, RP; Kong, AN; Li, W; Sargsyan, D; Su, ZY; Verzi, MP; Wang, C; Wu, R; Yin, R; Zhang, C | 1 |
Gong, D; Hu, JL; Liu, LQ; Nie, SP; Shen, MY; Xie, MY; Yu, Q | 1 |
Allaman, MM; Asim, M; Barry, DP; Cleveland, JL; Coburn, LA; Delgado, AG; Gobert, AP; Luis, PB; Piazuelo, MB; Schneider, C; Shi, C; Singh, K; Washington, MK; Wilson, KT | 1 |
Chastre, E; Jordan, P; Kotelevets, L; Lehy, T; Mamadou, G; Walker, F | 1 |
Booth, CJ; D'Souza, SS; Kartchner, BJ; Lee, EC; Malizia, RA; O'Connor, W; Sharp, SP; Stain, SC; Walrath, T | 1 |
Balboa, MA; Balsinde, J; Cubero, Á; García-Rostán, G; Győrffy, B; Lordén, G; Meana, C; Orduña, A; Peña, L | 1 |
Kim, N; Lee, DH; Lee, SM; Na, HY; Nam, RH; Sohn, SH; Song, CH; Surh, YJ | 1 |
Arruda, SF; Campos, NA; da Cunha, MSB | 1 |
Chen, H; De Lisio, M; Emmons, R; Hernández-Saavedra, D; Kriska, A; Pan, YX; Xu, G | 1 |
Hwang, S; Khalmuratova, R; Kim, JH; Kim, YS; Koh, SJ; Lee, GY; Lee, M; Park, JW; Shin, HW; Yoon, DW | 1 |
Arthur, JC; Rothemich, A | 1 |
Bader, JE; Carson, JA; Carson, M; Chatzistamou, I; Enos, RT; Kubinak, JL; Murphy, EA; Nagarkatti, M; Pena, MM; Sougiannis, AT; VanderVeen, BN; Velazquez, KT; Walla, M | 1 |
Brahmaroutu, A; DeMorrow, S; Frampton, G; Grant, S; Jefferson, B; McMillin, M; Petrescu, AD; Thomas, A; Williams, E | 1 |
Imai, T; Ishigamori, R; Ito, K; Mutoh, M; Ohta, T; Takahashi, M | 1 |
Gao, Y; Li, X; Liu, X; Lu, X; Wang, G; Wu, J; Wu, Q; Yang, M; Yang, Y; Zhang, Y; Zhao, Q | 1 |
Agarwal, C; Agarwal, R; Balaiya, V; Derry, MM; Huber, KM; Jain, AK; Raina, K; Serkova, NJ; Shrotriya, S | 1 |
Allred, CD; Allred, KF; Armstrong, CM; Billimek, AR; Sturino, JM; Weeks, BR | 1 |
Barrett, CW; Bradley, AM; Burk, RF; Chaturvedi, R; Davies, SS; Fingleton, BM; Hill, KE; Lintel, MK; Matafonova, E; Motley, AK; Ning, W; Parang, B; Poindexter, SV; Reddy, VK; Singh, K; Washington, MK; Williams, CS; Wilson, KT | 1 |
Bélanger, M; Butterworth, RF; Chastre, A; Nguyen, BN | 1 |
Banerjee, N; Kim, H; Mertens-Talcott, S; Talcott, S | 1 |
Knackstedt, R; Moseley, V; Shaoli, S; Wargovich, M | 1 |
Aguirre, V; Bartuzi, P; Ben-Shlomo, S; Burstein, E; Chan, L; Esko, T; Faubion, WA; Franke, L; Gluck, N; Hofker, M; Kracht, M; Kumar, V; Li, H; Mao, X; Melton, SD; Metspalu, A; Mokadem, M; Raetz, M; Schneider, H; Starokadomskyy, P; van de Sluis, B; van Sommeren, S; Varol, C; Weber, A; Weersma, RK; Weisberg, R; Westra, HJ; Wijmenga, C; Yarovinsky, F | 1 |
Li, H; Li, S; Liang, X; Tian, G | 1 |
Miller, MA; Neufeld, KL; Sullivan, R; Zeineldin, M | 1 |
Alam, F; Byun, Y; Chung, SW; Jeon, OC; Kim, JY; Kim, SY; Park, J; Son, WC | 1 |
Hosono, A; Seki, T; Takai, S; Yamaguchi, M | 1 |
Ai, F; Bian, Y; Dang, W; Fan, S; Huang, J; Li, G; Li, N; Ma, J; Qin, Z; Tang, A; Xiong, W; Yan, Q; Ye, Q; Zhang, X; Zheng, Y; Zhou, M; Zhou, Y | 1 |
Chen, Z; He, X; He, Z; Ke, J; Lan, P; Lian, L; Sun, L; Wu, X | 1 |
Barnholtz-Sloan, JS; Chen, Y; Dawson, DM; Fink, SP; Kopelovich, L; Kresak, A; Lawrence, EG; Markowitz, SD; Willis, JE; Yang, P; Zhang, Y | 1 |
Abdella, EM; El-Derby, AM; Mahmoud, AM | 1 |
Burkitt, MD; Caamano, JH; Dimaline, R; Duckworth, CA; Gerondakis, S; Hanedi, AF; O'Reilly, LA; Pritchard, DM; Putoczki, TL; Tang, JM; Williams, JM | 1 |
Gold, B; Whetstone, RD | 1 |
Araki, K; Baba, H; Hirashima, K; Ida, S; Maehara, Y; Miyamoto, Y; Morita, M; Ohmuraya, M; Oki, E; Ozaki, N; Sakamoto, Y; Taki, K; Watanabe, M; Yamamura, K; Zaitsu, Y | 1 |
Hou, YY; Lv, MM; Nie, YZ; Ren, J; Shen, SN; Tang, RJ; Wang, TT; Xu, YJ; Zhao, XY | 1 |
Deng, Z; Egilmez, NK; Guo, H; Haribabu, B; Miller, D; Mu, J; Norris, J; Tseng, M; Wang, Q; Wattenberg, B; Yan, J; Zhang, HG; Zhang, L; Zhuang, X | 1 |
Han, SB; Hong, JT; Kim, EC; Park, KR; Yoon, DY; Yun, HM | 1 |
Matsui, H; Nagasaki, Y; Vong, LB; Yoshitomi, T | 1 |
Cai, Y; Golla, JP; Golla, S; Gonzalez, FJ; Korboukh, I; Krausz, KW; Manna, SK; Matsubara, T; Takahashi, S; Tanaka, N | 1 |
Bertino, P; Hara, JH; Hashimoto, AS; Hoffmann, FW; Hoffmann, PR; Huang, Z; Mafnas, C; Rose, AH | 1 |
Fukushima, T; Haruyama, Y; Itoh, H; Kanemaru, A; Kangawa, K; Kataoka, H; Kawaguchi, M; Matsumoto, N; Nakazato, M; Tanaka, H; Yamamoto, K | 1 |
Dammann, K; Evstatiev, R; Gasche, C; Harpain, F; Khare, V; Kurtovic, A; Lang, M; Mesteri, I | 1 |
Chinikaylo, A; Chittur, SV; Gutierrez, LS; Lawler, J; Lippert, B; Lopez-Dee, ZP; Patel, B; Patel, H | 1 |
Kim, H; Lee, HA; Lee, KW; Park, KY | 1 |
Chaudhry, KK; Gangwar, R; Manda, B; Meena, AS; Mir, H; Rao, R; Shukla, PK; Yadav, N | 1 |
Calvo, JA; Muthupalani, S; Samson, LD; Yu, AM | 1 |
Chaiyasut, C; Reungpatthanaphong, S; Sirilun, S; Suwannalert, P | 1 |
Cai, X; Cao, P; Chen, G; Cheng, X; Hu, C; Wang, M; Xu, Y; Yang, CS; Yang, Y | 1 |
de Carvalho, JE; Dmitrieva, O; Francescone, R; Grivennikov, SI; Hensley, H; Hou, V; Pilli, RA; Posocco, D; Vendramini-Costa, DB | 1 |
Han, J; Ishibashi, R; Kato, N; Kishikawa, T; Koike, K; Miyazawa, M; Nakagawa, R; Ohno, M; Otsuka, M; Suzuki, N; Takata, A; Wu, J; Yamagami, M; Yoshikawa, T | 1 |
Hayashi, SM; Hippo, Y; Kangawa, Y; Kihara, T; Maruyama, K; Nakamura, M; Ochiai, M; Okamoto, M; Shibutani, M; Yoshida, T | 1 |
Bielawski, J; Hannun, YA; Kaneshiro, T; Kawamori, T; Maalouf, S; Obeid, LM; Okumura, M; Uflacker, A | 1 |
Albert, PS; Barrett, KG; Bennink, MR; Bobe, G; Colburn, NH; Lanza, E; Mentor-Marcel, RA; Young, MR | 1 |
Hao, X; Ju, J; Lambert, JD; Lee, MJ; Lu, G; Newmark, HL; Xiao, H; Yang, CS | 1 |
Caderni, G; Dolara, P; Femia, AP; Luceri, C; Salvadori, M | 1 |
Chasson, L; Clément, A; Galland, F; Garcia, S; Hofman, P; Issaly, N; Millet, V; Naquet, P; Pouyet, L; Roisin-Bouffay, C; Rostan, A | 1 |
Koketsu, M; Oyama, T; Sugie, S; Tanaka, T; Watanabe, K; Yasui, Y | 1 |
An, MJ; Cheon, JH; Kim, HM; Kim, SA; Kim, SK; Kim, SW; Kim, TI; Kim, WH; Lee, SK; Park, JJ; Yang, KM | 1 |
Hata, K; Hirose, Y; Kubota, M; Moriwaki, H; Sakai, H; Shimizu, M; Shirakami, Y; Tanaka, T; Tsurumi, H; Yasuda, Y | 1 |
Bémeur, C; Butterworth, RF; Desjardins, P; Vaquero, J | 1 |
Bala, S; DeSchryver, K; Jiang, S; Levin, MS; Newberry, R; Onal, B; Rubin, DC; Shaker, A; Swietlicki, EA; Wang, L | 1 |
Abreu, MT; Cooper, HS; Elson, G; España, C; Fukata, M; Harpaz, N; Kosco-Vilbois, M; Lira, SA; Mayer, L; Pastorini, C; Perez, MT; Santaolalla, R; Shang, L; Sotolongo, J; Ungaro, R; Vamadevan, AS; Zaias, J | 1 |
Choi, KS; Chung, MH; Hahm, KB; Han, YM; Hong, H; Hong, KS; Kim, EH; Ock, CY | 1 |
Endlicher, E; Grunwald, N; Lechner, A; Neumann, ID; Obermeier, F; Peters, S; Reber, SO; Rümmele, P | 1 |
Li, TW; Lu, SC; Mato, JM; Peng, H; Xia, M; Yang, H | 1 |
Banning, A; Brauer, MN; Brigelius-Flohé, R; Chu, FF; Esworthy, RS; Florian, S; Iori, R; Kipp, AP; Krehl, S; Loewinger, M; Wessjohann, LA | 1 |
Cheong, SJ; Jang, D; Jeong, HJ; Jeong, MH; Kim, DW; Kim, EM; Lee, CM; Lim, ST; Sohn, MH | 1 |
Brubaker, PL; El-Zimaity, HM; Trivedi, S; Wiber, SC | 1 |
Boulard, O; Kirchberger, S; Maloy, KJ; Powrie, FM; Royston, DJ | 1 |
Behan, NA; Brooks, SP; Caldwell, D; Green, J; MacFarlane, AJ; Matias, FM | 1 |
Hara, A; Hatano, Y; Hirata, A; Hirose, Y; Kuno, T; Masuda, S; Mori, H; Tanaka, T; Terasaki, M; Tomita, H | 1 |
Agis-Torres, A; Bravo, L; Goya, L; López-Oliva, E; Martín, MA; Ramos, S; Rodríguez-Ramiro, I | 1 |
Butler, SM; Jeffery, EH; Jung, SH; Lee, EH; Nho, CW; Pan, CH; Wallig, MA | 1 |
Chitra, P; Manikandan, R; Saiprasad, G; Sudhandiran, G | 1 |
Kohno, H; Mori, H; Sugie, S; Suzuki, R; Tanaka, T; Yamada, Y | 1 |
Auwerx, J; Dubuquoy, L; Fayard, E; Geboes, K; Haby, C; Mebis, J; Schoonjans, K; Wendling, O | 1 |
Kohno, H; Sugie, S; Suzuki, R; Tanaka, T | 1 |
Bruce, WR; Hughes, R; Karlsson, PC; Rafter, JJ | 1 |
Miyamoto, S; Sugie, S; Suzuki, R; Tanaka, T; Yasui, Y | 1 |
Carroll, RE; Fernandez, PA; Hagos, GK; Kouznetsova, T; Li, Q; Swanson, SM; Thatcher, GR; Toader, V | 1 |
DuBois, RN; Radhika, A; Shattuck-Brandt, RL; Varilek, GW; Washington, MK; Yang, F | 1 |
130 other study(ies) available for azoxymethane and Inflammation
Article | Year |
---|---|
GPR65 (TDAG8) inhibits intestinal inflammation and colitis-associated colorectal cancer development in experimental mouse models.
Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colon; Dextran Sulfate; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Humans; Inflammation; Inflammatory Bowel Diseases; Leukocytes; Mice; Mice, Knockout; Receptors, G-Protein-Coupled; Severity of Illness Index | 2022 |
Applications and Mechanism of 3-Hydroxybutyrate (3HB) for Prevention of Colonic Inflammation and Carcinogenesis as a Food Supplement.
Topics: 3-Hydroxybutyric Acid; Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL | 2021 |
TIPE2 Promotes Tumor Initiation But Inhibits Tumor Progression in Murine Colitis-Associated Colon Cancer.
Topics: Animals; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colitis-Associated Neoplasms; Colon; Dextran Sulfate; Disease Models, Animal; Inflammation; Inflammatory Bowel Diseases; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL | 2022 |
Pre-Administration of Berberine Exerts Chemopreventive Effects in AOM/DSS-Induced Colitis-Associated Carcinogenesis Mice via Modulating Inflammation and Intestinal Microbiota.
Topics: Animals; Azoxymethane; Berberine; Carcinogenesis; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Mice; Mice, Inbred C57BL; RNA, Ribosomal, 16S | 2022 |
Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Lactobacillaceae; Metabolome; Mice; Mice, Inbred C57BL | 2022 |
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Kefir; Lactobacillus; Mice; RNA, Ribosomal, 16S; Saccharomyces cerevisiae; Tibet | 2022 |
Lacticaseibacillus rhamnosus LS8 Ameliorates Azoxymethane/Dextran Sulfate Sodium-Induced Colitis-Associated Tumorigenesis in Mice via Regulating Gut Microbiota and Inhibiting Inflammation.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Dextran Sulfate; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Lacticaseibacillus rhamnosus; Mice | 2022 |
Aspirin Inhibits Carcinogenesis of Intestinal Mucosal Cells in UC Mice Through Inhibiting IL-6/JAK/STAT3 Signaling Pathway and Modulating Apoptosis and Proliferation.
Topics: Animals; Apoptosis; Aspirin; Azoxymethane; Carcinogenesis; Cell Proliferation; Colitis, Ulcerative; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Hyperplasia; Inflammation; Interleukin-10; Interleukin-6; Janus Kinases; Mice; Proliferating Cell Nuclear Antigen; Signal Transduction; STAT3 Transcription Factor | 2022 |
Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer.
Topics: Animals; Azoxymethane; Bacteroidetes; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Firmicutes; Humans; Inflammation; Mice; Mice, Inbred C57BL; Naphthoquinones; Tumor Microenvironment | 2022 |
6- shogaol suppresses AOM/DSS-mediated colorectal adenoma through its antioxidant and anti-inflammatory effects in mice.
Topics: Adenoma; Animals; Anti-Inflammatory Agents; Antioxidants; Azoxymethane; Colonic Neoplasms; Colorectal Neoplasms; Disease Models, Animal; Inflammation; Male; Mice | 2022 |
Colitis Induces Sex-Specific Intestinal Transcriptomic Responses in Mice.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Humans; Inflammation; Inflammatory Bowel Diseases; Male; Mice; Mice, Inbred C57BL; Receptors, Glucocorticoid; RNA; Transcriptome | 2022 |
Establishment of a Novel Colitis-Associated Cancer Mouse Model Showing Flat Invasive Neoplasia.
Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Dextrans; Disease Models, Animal; Humans; Inflammation; Mice; Reproducibility of Results | 2023 |
Ginsenoside Rb1 Suppresses AOM/DSS-induced Colon Carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colorectal Neoplasms; Disease Models, Animal; Ginsenosides; Inflammation; Mice; Mice, Inbred C57BL; Tumor Microenvironment | 2023 |
Boris knockout eliminates AOM/DSS-induced in situ colorectal cancer by suppressing DNA damage repair and inflammation.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; DNA Damage; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout | 2023 |
Panaxynol alleviates colorectal cancer in a murine model via suppressing macrophages and inflammation.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mucins | 2023 |
Anticancer Effects of Washed-Dehydrated Solar Salt Doenjang on Colon Cancer-Induced C57BL/6 Mice.
Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Inflammation; Interleukin-6; Mice; Mice, Inbred C57BL; Sodium Chloride, Dietary; Tumor Necrosis Factor-alpha | 2023 |
Astragaloside IV inhibits AOM/DSS-induced colitis-associated tumorigenesis via activation of PPARγ signaling in mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Dextran Sulfate; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; PPAR gamma; Reactive Oxygen Species | 2023 |
Fecal microbiota transplanted from old mice promotes more colonic inflammation, proliferation, and tumor formation in azoxymethane-treated A/J mice than microbiota originating from young mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Colonic Neoplasms; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Inflammation; Mice; Microbiota | 2023 |
Thermally Processed Oil Exaggerates Colonic Inflammation and Colitis-Associated Colon Tumorigenesis in Mice.
Topics: Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Hot Temperature; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; Oils | 2019 |
Orally Deliverable Nanotherapeutics for the Synergistic Treatment of Colitis-Associated Colorectal Cancer.
Topics: Administration, Oral; Animals; Apoptosis; Azoxymethane; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colitis; Colorectal Neoplasms; Curcumin; Cytokines; Dextran Sulfate; Disease Models, Animal; Disease Progression; Drug Synergism; Female; Inflammation; Inflammation Mediators; Intestines; Irinotecan; Macrophages; Mice; Mice, Inbred C57BL; Nanoparticles; RAW 264.7 Cells | 2019 |
Clerodane Diterpene Ameliorates Inflammatory Bowel Disease and Potentiates Cell Apoptosis of Colorectal Cancer.
Topics: Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Caco-2 Cells; Cell Cycle; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dextran Sulfate; Diterpenes, Clerodane; Fluorouracil; HT29 Cells; Humans; Inflammation; Inflammatory Bowel Diseases; Intestines; Male; Mice, Inbred C57BL | 2019 |
The impact of gut microbiota manipulation with antibiotics on colon tumorigenesis in a murine model.
Topics: Animals; Anti-Bacterial Agents; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Microbiome; High-Throughput Nucleotide Sequencing; Inflammation; Mice; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Tumor Burden | 2019 |
Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation.
Topics: Adaptor Proteins, Signal Transducing; Adenomatous Polyposis Coli; Animals; Azoxymethane; Carcinogenesis; Cell Adhesion Molecules; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Focal Adhesion Protein-Tyrosine Kinases; Humans; Inflammation; Integrins; Interleukin-6; Intestines; Mice, Inbred C57BL; Myofibroblasts; Precancerous Conditions; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Stromal Cells; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins | 2020 |
Reduction of colitis-associated colon carcinogenesis by a black lentil water extract through inhibition of inflammatory and immunomodulatory cytokines.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Fabaceae; Gene Expression Profiling; Inflammation; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Water | 2020 |
Consumption of the Total Western Diet Promotes Colitis and Inflammation-Associated Colorectal Cancer in Mice.
Topics: Adaptive Immunity; Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Diet, Western; Disease Models, Animal; Immunity, Innate; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; RNA, Messenger | 2020 |
Parabacteroides distasonis attenuates tumorigenesis, modulates inflammatory markers and promotes intestinal barrier integrity in azoxymethane-treated A/J mice.
Topics: Animals; Azoxymethane; Bacteroidetes; Carcinogenesis; Colon; Colonic Neoplasms; Humans; Inflammation; Interleukin-4; Intestinal Mucosa; Mice; Obesity; Signal Transduction; Toll-Like Receptor 4; Transforming Growth Factor beta | 2020 |
miR-370-3p Alleviates Ulcerative Colitis-Related Colorectal Cancer in Mice Through Inhibiting the Inflammatory Response and Epithelial-Mesenchymal Transition.
Topics: Animals; Azoxymethane; Cell Proliferation; Cells, Cultured; Colitis, Ulcerative; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Epithelial-Mesenchymal Transition; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; MicroRNAs | 2020 |
Lactobacillus species inhibitory effect on colorectal cancer progression through modulating the Wnt/β-catenin signaling pathway.
Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Female; Flow Cytometry; Gastrointestinal Microbiome; HT29 Cells; Humans; Inflammation; Lactobacillus; Mice; Mice, Inbred BALB C; Probiotics; Real-Time Polymerase Chain Reaction; Wnt Signaling Pathway | 2020 |
Extracellular Granzyme A Promotes Colorectal Cancer Development by Enhancing Gut Inflammation.
Topics: Acute Disease; Animals; Azoxymethane; Carcinogenesis; Chronic Disease; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Disease Progression; Extracellular Space; Granzymes; Humans; Inflammasomes; Inflammation; Inflammation Mediators; Interleukin-6; Mice, Knockout; NF-kappa B; RNA, Messenger | 2020 |
Clostridium butyricum modulates gut microbiota and reduces colitis associated colon cancer in mice.
Topics: Animals; Apoptosis; Azoxymethane; Bacteroidetes; Body Weight; Cell Proliferation; Clostridium butyricum; Colitis; Colitis-Associated Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Feces; Firmicutes; Gastrointestinal Microbiome; Inflammation; Male; Mice, Inbred C57BL; NF-kappa B p50 Subunit; RNA, Ribosomal, 16S | 2020 |
Effects of combined treatment with Indomethacin and Juglone on AOM/DSS induced colon carcinogenesis in Balb/c mice: Roles of inflammation and apoptosis.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogenesis; Cell Count; Cell Line, Tumor; Collagen; Colonic Neoplasms; Dextran Sulfate; Indomethacin; Inflammation; Male; Mast Cells; Mice, Inbred BALB C; Naphthoquinones | 2021 |
The Glucocorticoid Receptor in Intestinal Epithelial Cells Alleviates Colitis and Associated Colorectal Cancer in Mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colitis-Associated Neoplasms; Dextran Sulfate; Female; Gene Expression Profiling; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Knockout; Permeability; Receptors, Glucocorticoid | 2021 |
Inducible mouse models of colon cancer for the analysis of sporadic and inflammation-driven tumor progression and lymph node metastasis.
Topics: Animals; Azoxymethane; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Progression; Female; Inflammation; Lymphatic Metastasis; Male; Mice; Mice, Inbred C57BL | 2021 |
Vitamin E delta-tocotrienol and metabolite 13'-carboxychromanol inhibit colitis-associated colon tumorigenesis and modulate gut microbiota in mice.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Benzopyrans; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Fatty Acids; Feces; Gastrointestinal Microbiome; Humans; Inflammation; Interleukin-1beta; Male; Mice; Mice, Inbred BALB C; RNA, Ribosomal, 16S; Vitamin E | 2021 |
Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis.
Topics: Acrolein; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred A; RNA-Binding Proteins | 2021 |
Glutathione transferase Omega 1 confers protection against azoxymethane-induced colorectal tumour formation.
Topics: Animals; Azoxymethane; Carcinogens; Carrier Proteins; Colitis; Colorectal Neoplasms; Dextran Sulfate; Glutathione Transferase; Inflammation; Interleukin-18; Interleukin-1beta; Mice; Mice, Inbred C57BL; Mice, Knockout | 2021 |
Glycyrrhizin Attenuates Carcinogenesis by Inhibiting the Inflammatory Response in a Murine Model of Colorectal Cancer.
Topics: Animals; Azoxymethane; Carcinogenesis; Colon; Colorectal Neoplasms; Disease Models, Animal; Female; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Interleukin-6; Mice; Mice, Inbred ICR; NF-kappa B; Signal Transduction; Tumor Necrosis Factor-alpha | 2021 |
Inhibitory effects of a selective prostaglandin E2 receptor antagonist RQ-15986 on inflammation-related colon tumorigenesis in APC-mutant rats.
Topics: Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; Benzamides; Carcinogenesis; Cell Proliferation; Chemokine CCL2; Colonic Neoplasms; Dextran Sulfate; Dinoprostone; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Interleukin-18; Interleukin-6; Mutation; Rats; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Tumor Necrosis Factor-alpha | 2021 |
Limonin modulated immune and inflammatory responses to suppress colorectal adenocarcinoma in mice model.
Topics: Adenocarcinoma; Animals; Antioxidants; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Limonins; Male; Mice; Mice, Inbred BALB C; Oxidative Stress | 2021 |
Chemoprotective Effects of Geraniin against Azoxymethane Induced Colorectal Cancer by Reduction of Inflammatory Reaction.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Azoxymethane; Body Weight; Colorectal Neoplasms; Cytokines; Enzymes; Female; Glucosides; Hydrolyzable Tannins; Inflammation; Male; Oxidative Stress; Rats, Wistar | 2021 |
Ganoderma lucidum polysaccharide modulates gut microbiota and immune cell function to inhibit inflammation and tumorigenesis in colon.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Dysbiosis; Fungal Polysaccharides; Gastrointestinal Microbiome; Humans; Inflammation; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; RAW 264.7 Cells; Reishi; Signal Transduction | 2021 |
Overproduction of Gastrointestinal 5-HT Promotes Colitis-Associated Colorectal Cancer Progression via Enhancing NLRP3 Inflammasome Activation.
Topics: Animals; Azoxymethane; Cell Line, Tumor; Colitis-Associated Neoplasms; Dextran Sulfate; Gastrointestinal Tract; Humans; Inflammasomes; Inflammation; Interleukin-1beta; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Serotonin; Signal Transduction; Tryptophan Hydroxylase | 2021 |
Anti-Obesity Drug Orlistat Alleviates Western-Diet-Driven Colitis-Associated Colon Cancer via Inhibition of STAT3 and NF-κB-Mediated Signaling.
Topics: Animals; Anti-Obesity Agents; Antineoplastic Agents; Azoxymethane; Colitis-Associated Neoplasms; Dextran Sulfate; Diet, Western; Inflammation; Mice; NF-kappa B; Orlistat; Signal Transduction; STAT3 Transcription Factor; Transcription Factor RelA | 2021 |
Lack of STAT6 Attenuates Inflammation and Drives Protection against Early Steps of Colitis-Associated Colon Cancer.
Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Cell Proliferation; Colitis; Colon; Colonic Neoplasms; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Female; Inflammation; Mice, Inbred BALB C; Mice, Knockout; RNA, Messenger; STAT6 Transcription Factor | 2017 |
Clostridium butyricum partially regulates the development of colitis-associated cancer through miR-200c.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Clostridium butyricum; Colitis; Colonic Neoplasms; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization, Fluorescence; Inflammation; Interleukin-12; Mice; MicroRNAs; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2017 |
Inhibition of MK2 suppresses IL-1β, IL-6, and TNF-α-dependent colorectal cancer growth.
Topics: Animals; Azoxymethane; Cell Line, Tumor; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Female; Inflammation; Interleukin-1beta; Interleukin-6; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Protein Serine-Threonine Kinases; Signal Transduction; Tumor Necrosis Factor-alpha | 2018 |
Methylglyoxal displays colorectal cancer-promoting properties in the murine models of azoxymethane and CT26 isografts.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Cell Line; Cholesterol, LDL; Colorectal Neoplasms; Disease Models, Animal; Humans; Inflammation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Oxidative Stress; Precancerous Conditions; Pyruvaldehyde; Transplantation, Isogeneic | 2018 |
Elevated d-2-hydroxyglutarate during colitis drives progression to colorectal cancer.
Topics: Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Biopsy; Caco-2 Cells; Cell Movement; Cell Proliferation; Cell Survival; Colitis; Colitis, Ulcerative; Colorectal Neoplasms; Dextran Sulfate; Disease Progression; Glutarates; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Intestinal Mucosa; Mice; Risk | 2018 |
Chemopreventive Effect of Aster glehni on Inflammation-Induced Colorectal Carcinogenesis in Mice.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Aster Plant; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dextran Sulfate; Inflammation; Interleukins; Male; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Spleen; Tumor Necrosis Factor-alpha | 2018 |
Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colitis; Colonic Neoplasms; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dextran Sulfate; Disease Progression; Epigenesis, Genetic; Histone Deacetylases; Homeostasis; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Neutrophils; Receptors, G-Protein-Coupled | 2018 |
DNA methylome and transcriptome alterations and cancer prevention by curcumin in colitis-accelerated colon cancer in mice.
Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Curcumin; Dextran Sulfate; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Inflammation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Transcriptome | 2018 |
Tea Polysaccharides Inhibit Colitis-Associated Colorectal Cancer via Interleukin-6/STAT3 Pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Azoxymethane; Camellia sinensis; Cell Line, Tumor; Colitis; Colorectal Neoplasms; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Inflammation; Interleukin-6; Macrophages; Mice; Mice, Inbred BALB C; Polysaccharides; RAW 264.7 Cells; Signal Transduction; STAT3 Transcription Factor; Tea | 2018 |
Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis, Ulcerative; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Inflammation; Macrophage Activation; Macrophages; Male; Mice; Ornithine Decarboxylase; Transcription, Genetic; Up-Regulation | 2018 |
The Rac1 splice form Rac1b favors mouse colonic mucosa regeneration and contributes to intestinal cancer progression.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Progression; Epithelial Cells; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Neuropeptides; rac1 GTP-Binding Protein; Signal Transduction | 2018 |
DNA damage response genes mark the early transition from colitis to neoplasia in colitis-associated colon cancer.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Progression; DNA Damage; Gene Expression Regulation; Inflammation; Inflammatory Bowel Diseases; Intestines; Male; Mice; Mice, Inbred C57BL; Microsatellite Instability; Signal Transduction | 2018 |
The phosphatidic acid phosphatase lipin-1 facilitates inflammation-driven colon carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Chemokine CXCL1; Chemokine CXCL2; Colitis; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Humans; Inflammation; Inflammatory Bowel Diseases; Interleukin-23; Macrophages; Mice; Mice, Inbred BALB C; Mucous Membrane; Nuclear Proteins; Phosphatidate Phosphatase | 2018 |
Effects of 17β-Estradiol on Colonic Permeability and Inflammation in an Azoxymethane/Dextran Sulfate Sodium-Induced Colitis Mouse Model.
Topics: Animals; Azoxymethane; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Estradiol; Inflammation; Intestinal Mucosa; Kruppel-Like Factor 4; Male; Mice; Mucin-2; Permeability; Signal Transduction; Tight Junctions | 2018 |
Tucum-do-cerrado (Bactris setosa Mart.) modulates oxidative stress, inflammation, and apoptosis-related proteins in rats treated with azoxymethane.
Topics: Animals; Apoptosis; Arecaceae; Azoxymethane; Colon; Colonic Neoplasms; Disease Models, Animal; Fruit; Inflammation; Liver; Male; Oxidative Stress; Phytotherapy; Rats, Wistar | 2018 |
Effects of obesity and exercise on colon cancer induction and hematopoiesis in mice.
Topics: Adipose Tissue; Animals; Azoxymethane; Bone Marrow; Carcinogens; Colonic Neoplasms; Diet, High-Fat; Hematopoiesis; Hematopoietic Stem Cells; Inflammation; Mice; Myeloid Progenitor Cells; Neoplasms, Experimental; Obesity; Physical Conditioning, Animal; Proteomics; Random Allocation; Sedentary Behavior | 2019 |
Intermittent hypoxia promotes carcinogenesis in azoxymethane and dextran sodium sulfate-induced colon cancer model.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Hypoxia; Inflammation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress | 2019 |
The Azoxymethane/Il10
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Disease Models, Animal; Germ-Free Life; Inflammation; Inflammatory Bowel Diseases; Interleukin-10; Intestines; Mice, Knockout | 2019 |
Impact of 5 fluorouracil chemotherapy on gut inflammation, functional parameters, and gut microbiota.
Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Fecal Microbiota Transplantation; Fluorouracil; Gastrointestinal Microbiome; Inflammation; Male; Mice; Mice, Inbred C57BL | 2019 |
Elevated circulating TGFβ1 during acute liver failure activates TGFβR2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice.
Topics: Animals; Antibodies; Azoxymethane; Benzamides; Carcinogens; Cell Line, Transformed; Cerebral Cortex; Disease Models, Animal; Hepatic Encephalopathy; Inflammation; Isoquinolines; Liver; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neurons; Phagocytosis; Pyrazoles; Pyridines; Pyrroles; Receptor, Transforming Growth Factor-beta Type II; Signal Transduction; Transforming Growth Factor beta1; Up-Regulation | 2019 |
Ay allele promotes azoxymethane-induced colorectal carcinogenesis by macrophage migration in hyperlipidemic/diabetic KK mice.
Topics: Alleles; Animals; Azoxymethane; beta Catenin; Carcinogenesis; Cell Movement; Cocarcinogenesis; Colorectal Neoplasms; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Hyperlipidemias; Inflammation; Insulin; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Inbred NOD; RNA, Messenger; Triglycerides | 2013 |
Colitis-accelerated colorectal cancer and metabolic dysregulation in a mouse model.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Inflammation; Metabolic Diseases; Mice; Mice, Inbred BALB C; MicroRNAs; RNA, Messenger; Transcriptome; Up-Regulation; Wnt Proteins | 2013 |
Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Azoxymethane; beta Catenin; Biomarkers, Tumor; Blotting, Western; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Cytokines; Extracellular Signal-Regulated MAP Kinases; Gene Expression Profiling; Grape Seed Extract; Immunoenzyme Techniques; Inflammation; Male; Mice; Mice, Inbred A; MicroRNAs; Mitogen-Activated Protein Kinases; NF-kappa B; Oligonucleotide Array Sequence Analysis; Phosphorylation; Signal Transduction | 2013 |
A novel shift in estrogen receptor expression occurs as estradiol suppresses inflammation-associated colon tumor formation.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Colonic Neoplasms; Dextran Sulfate; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout | 2013 |
Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Azoxymethane; Carcinogenesis; Colitis; Colonic Neoplasms; Deoxyguanosine; Dextran Sulfate; Diet; DNA Damage; Epidermal Growth Factor; Gene Expression Regulation; Inflammation; Mice; Mice, Inbred C57BL; Selenium; Signal Transduction; Transforming Growth Factor beta; Weight Loss | 2013 |
Lipopolysaccharide precipitates hepatic encephalopathy and increases blood-brain barrier permeability in mice with acute liver failure.
Topics: Ammonia; Animals; Azoxymethane; Blood-Brain Barrier; Cytokines; Disease Models, Animal; Hepatic Encephalopathy; Inflammation; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Permeability; Transaminases | 2014 |
Pomegranate polyphenolics suppressed azoxymethane-induced colorectal aberrant crypt foci and inflammation: possible role of miR-126/VCAM-1 and miR-126/PI3K/AKT/mTOR.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Beverages; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; HT29 Cells; Humans; Inflammation; Lythraceae; Male; MicroRNAs; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinase; Polyphenols; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases; Vascular Cell Adhesion Molecule-1 | 2013 |
The importance of the retinoid X receptor alpha in modulating inflammatory signaling in acute murine colitis.
Topics: Animals; Azoxymethane; Carcinogens; Colitis; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Heterozygote; Immunoblotting; Inflammation; Mice; Receptors, Calcitriol; Retinoid X Receptor alpha | 2014 |
Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer.
Topics: Adaptor Proteins, Signal Transducing; Animals; Azoxymethane; Biopsy; Case-Control Studies; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Inflammation; Inflammatory Bowel Diseases; Mice; Mice, Knockout; NF-kappa B; Polymorphism, Single Nucleotide; RNA, Messenger | 2014 |
Dynamic microbe and molecule networks in a mouse model of colitis-associated colorectal cancer.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Tract; Inflammation; Male; Mice; Mice, Inbred BALB C; RNA, Ribosomal, 16S | 2014 |
Nuclear adenomatous polyposis coli suppresses colitis-associated tumorigenesis in mice.
Topics: Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Azoxymethane; beta Catenin; Blotting, Western; Carcinogens; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Disease Models, Animal; Inflammation; Mice; Mutation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2014 |
Combinational chemoprevention effect of celecoxib and an oral antiangiogenic LHD4 on colorectal carcinogenesis in mice.
Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Celecoxib; Colon; Colonic Polyps; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Deoxycholic Acid; Dextran Sulfate; Drug Therapy, Combination; Heparin, Low-Molecular-Weight; Inflammation; Male; Mice, Inbred ICR; Neovascularization, Pathologic; Pyrazoles; Sulfonamides; Tumor Burden | 2014 |
Bovine milk-derived α-lactalbumin inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sodium sulfate-treated mice.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Carcinogenesis; Cattle; Colon; Colonic Neoplasms; Dextran Sulfate; Dietary Supplements; Dinoprostone; Inflammation; Interleukin-1beta; Lactalbumin; Male; Mice; Mice, Inbred C57BL; Milk; Occult Blood; Organ Size; Tumor Necrosis Factor-alpha | 2014 |
Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.
Topics: Animals; Apoptosis; Azoxymethane; Cell Proliferation; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Gene Knockout Techniques; Humans; Inflammation; Lactoferrin; Male; Mice; NF-kappa B; Signal Transduction | 2014 |
[Inflammation promotes the development of colitis-associated colorectal cancer].
Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Immunohistochemistry; Inflammation; Interleukin-6; Mice; Mice, Inbred C57BL; Signal Transduction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha | 2014 |
Sulindac reversal of 15-PGDH-mediated resistance to colon tumor chemoprevention with NSAIDs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Azoxymethane; Carcinogens; Celecoxib; Chemoprevention; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Hydroxyprostaglandin Dehydrogenases; Inflammation; Intestinal Mucosa; Membrane Proteins; Mice; Mice, Knockout; Pyrazoles; Sulfonamides; Sulindac | 2015 |
Protective Effects of Turbinaria ornata and Padina pavonia against Azoxymethane-Induced Colon Carcinogenesis through Modulation of PPAR Gamma, NF-κB and Oxidative Stress.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Colonic Neoplasms; Glutathione; Glutathione Peroxidase; Humans; Inflammation; Lipid Peroxidation; Male; Malondialdehyde; Mice; NF-kappa B; Nitric Oxide; Oxidative Stress; Phaeophyceae; PPAR gamma; Seaweed; Superoxide Dismutase; Tumor Suppressor Protein p53 | 2015 |
NF-κB1, NF-κB2 and c-Rel differentially regulate susceptibility to colitis-associated adenoma development in C57BL/6 mice.
Topics: Adenoma; Animals; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Disease Susceptibility; Epithelial Cells; Female; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B p50 Subunit; NF-kappa B p52 Subunit; Proto-Oncogene Proteins c-rel; Signal Transduction | 2015 |
T-cells enhance stem cell mutagenesis in the mouse colon.
Topics: Animals; Azoxymethane; Colon; Colonic Neoplasms; Dextran Sulfate; DNA Damage; Drug Synergism; Guanine; Inflammation; Male; Mice, Inbred C57BL; Mice, Knockout; Mutagenesis; Receptors, Antigen, T-Cell, alpha-beta; Stem Cells; T-Lymphocytes | 2015 |
SPINK1 Status in Colorectal Cancer, Impact on Proliferation, and Role in Colitis-Associated Cancer.
Topics: Aged; Animals; Azoxymethane; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Colitis; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Glycoproteins; Humans; Inflammation; Japan; Male; Mice, Inbred C57BL; Middle Aged; Prostatic Secretory Proteins; Trypsin Inhibitor, Kazal Pancreatic | 2015 |
Mesenchymal stem cells-regulated Treg cells suppress colitis-associated colorectal cancer.
Topics: Animals; Azoxymethane; CD4 Lymphocyte Count; Cell Differentiation; Cell Line; Cell Movement; Cell- and Tissue-Based Therapy; Colitis; Colon; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Humans; Inflammation; Jurkat Cells; Lymphocyte Activation; Lymphocyte Count; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Signal Transduction; Smad2 Protein; T-Lymphocytes, Regulatory; Th17 Cells; Th2 Cells; Umbilical Cord | 2015 |
Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis.
Topics: Adenocarcinoma; Animals; Azoxymethane; Bacteroides fragilis; Blotting, Western; Carcinogenesis; Carcinogens; Cell Line, Tumor; Cell Proliferation; Chemokine CCL20; Colitis; Colonic Neoplasms; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Enterobacteriaceae; Exosomes; Immunohistochemistry; In Situ Hybridization, Fluorescence; Inflammation; Intestinal Mucosa; Lysophospholipids; Mice; Myeloid Differentiation Factor 88; Nanoparticles; Neoplasm Transplantation; Reverse Transcriptase Polymerase Chain Reaction; Sphingosine; Th17 Cells | 2015 |
IL-32α suppresses colorectal cancer development via TNFR1-mediated death signaling.
Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; Enzyme Activation; Humans; Inflammation; Interleukins; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Transgenic; Neoplasm Proteins; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins; Signal Transduction | 2015 |
Development of an oral nanotherapeutics using redox nanoparticles for treatment of colitis-associated colon cancer.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Azoxymethane; Camptothecin; Cell Line, Tumor; Colitis; Colonic Neoplasms; Dextrans; Drug Delivery Systems; Drug Screening Assays, Antitumor; Endoscopy; Free Radical Scavengers; Inflammation; Irinotecan; Male; Mice; Mice, Inbred ICR; Nanomedicine; Nanoparticles; Neoplasms, Experimental; Nitrogen Oxides; Oxidation-Reduction; Reactive Oxygen Species; Sulfates | 2015 |
St. John's Wort Attenuates Colorectal Carcinogenesis in Mice through Suppression of Inflammatory Signaling.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; Diet; Dietary Supplements; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Hypericum; Inflammation; Male; Mice; NF-kappa B; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Plant Extracts; Signal Transduction | 2015 |
Calpain-2 Inhibitor Therapy Reduces Murine Colitis and Colitis-associated Cancer.
Topics: Animals; Azoxymethane; Cell Proliferation; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; HT29 Cells; Humans; I-kappa B Proteins; Inflammation; Injections, Intraperitoneal; Macrophage Activation; Mice; NF-kappa B; Oligopeptides; Translocation, Genetic | 2015 |
Ghrelin administration suppresses inflammation-associated colorectal carcinogenesis in mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Ghrelin; Inflammation; Male; Mice; Mice, Inbred C57BL | 2015 |
PAK1 promotes intestinal tumor initiation.
Topics: Animals; Azoxymethane; beta Catenin; Carcinogenesis; Colonoscopy; Dextrans; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Genotype; Heterozygote; Immunohistochemistry; Inflammation; Intestinal Neoplasms; Male; Mesalamine; Mice; Mice, Inbred C57BL; Mice, Knockout; p21-Activated Kinases; Signal Transduction | 2015 |
Thrombospondin-1 in a Murine Model of Colorectal Carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Immunohistochemistry; Inflammation; Mice, Inbred C57BL; Microvessels; Reproducibility of Results; RNA, Messenger; Thrombospondin 1; Up-Regulation | 2015 |
Dead Nano-Sized Lactobacillus plantarum Inhibits Azoxymethane/Dextran Sulfate Sodium-Induced Colon Cancer in Balb/c Mice.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogenesis; Cell Cycle Checkpoints; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Immunoglobulin A; Inflammation; Lactobacillus plantarum; Mice, Inbred BALB C; Particle Size | 2015 |
Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation.
Topics: Animals; Azoxymethane; Biomarkers, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chemokines; Colonic Neoplasms; Cytokines; Dextran Sulfate; Ethanol; Female; Gene Expression; Inflammation; Intestinal Mucosa; Mice; Protein Transport | 2016 |
The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury.
Topics: Animals; Apoptosis; Azoxymethane; Colon; Colonic Neoplasms; Dextran Sulfate; DNA Glycosylases; Endodeoxyribonucleases; Humans; Inflammation; Intestinal Mucosa; Kaplan-Meier Estimate; Mice, Knockout; Tumor Burden | 2016 |
Unpolished Thai Rice Prevents Aberrant Crypt Foci Formation through the Invovement of ?catenin and COX2 Expression in AzoxymethaneTreated Rats.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Biomarkers; Catenins; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase 2; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-6; Male; Oryza; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Thailand | 2016 |
Protective effects of Huangqin Decoction against ulcerative colitis and associated cancer in mice.
Topics: Animals; Antioxidants; Azoxymethane; Chromatography, High Pressure Liquid; Colitis, Ulcerative; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Drugs, Chinese Herbal; Flavanones; Inflammation; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Oxidative Stress; Plant Extracts; Scutellaria baicalensis | 2016 |
Anti-inflammatory natural product goniothalamin reduces colitis-associated and sporadic colorectal tumorigenesis.
Topics: Animals; Anti-Inflammatory Agents; Azoxymethane; Biological Products; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Inflammation; Inflammation Mediators; Macrophages; Mice; Mice, Inbred C57BL; Pyrones | 2017 |
Repression of MicroRNA Function Mediates Inflammation-associated Colon Tumorigenesis.
Topics: Animals; Azoxymethane; Caco-2 Cells; Carcinogenesis; Carcinoma; Cell Line, Tumor; Colitis; Colon; Colonic Neoplasms; Cytidine Deaminase; Cytokines; DEAD-box RNA Helicases; Dextran Sulfate; Fibroblasts; Flow Cytometry; HCT116 Cells; HT29 Cells; Humans; Immunoblotting; Immunohistochemistry; Inflammation; Interleukin-1alpha; Interleukin-1beta; Mice; MicroRNAs; Ribonuclease III; Tumor Necrosis Factor-alpha | 2017 |
Cilostazol and enzymatically modified isoquercitrin attenuate experimental colitis and colon cancer in mice by inhibiting cell proliferation and inflammation.
Topics: Animals; Azoxymethane; Carcinogens; Cell Proliferation; Cilostazol; Colitis; Colonic Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; Immunohistochemistry; Inflammation; Mice; Mice, Inbred BALB C; Organ Size; Quercetin; Tetrazoles; Vasodilator Agents | 2017 |
Role for sphingosine kinase 1 in colon carcinogenesis.
Topics: Animals; Azoxymethane; Cell Transformation, Neoplastic; Colonic Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Lysophospholipids; Mice; Mice, Knockout; Phosphotransferases (Alcohol Group Acceptor); Sphingosine | 2009 |
Inflammation-associated serum and colon markers as indicators of dietary attenuation of colon carcinogenesis in ob/ob mice.
Topics: Animals; Azoxymethane; Biomarkers, Tumor; Carcinogens; Colonic Neoplasms; Cytokines; Diet; Fabaceae; Gene Expression; Inflammation; Interleukin-6; Male; Mice; Mice, Obese; Obesity; Phytotherapy; Plant Extracts; Precancerous Conditions; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
A gamma-tocopherol-rich mixture of tocopherols inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sulfate sodium-treated mice.
Topics: Adenocarcinoma; Adenoma; Animals; Antioxidants; Apoptosis; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Colon; Colonic Neoplasms; Dextran Sulfate; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; gamma-Tocopherol; Inflammation; Leukotriene B4; Male; Mice; Tyrosine | 2009 |
Mucin-depleted foci show strong activation of inflammatory markers in 1,2-dimethylhydrazine-induced carcinogenesis and are promoted by the inflammatory agent sodium dextran sulfate.
Topics: 1,2-Dimethylhydrazine; Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Inflammation; Male; Mucin-2; Nitric Oxide Synthase Type II; Precancerous Conditions; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2009 |
Epithelial vanin-1 controls inflammation-driven carcinogenesis in the colitis-associated colon cancer model.
Topics: Amidohydrolases; Animals; Azoxymethane; Blotting, Western; Carcinogens; Cell Adhesion Molecules; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Epithelial Cells; Female; Fluorescent Antibody Technique; GPI-Linked Proteins; Inflammation; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Dietary tricin suppresses inflammation-related colon carcinogenesis in male Crj: CD-1 mice.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Blotting, Western; Carcinogens; Colonic Neoplasms; Diet; Flavonoids; Inflammation; Male; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
Bifidobacterium lactis inhibits NF-kappaB in intestinal epithelial cells and prevents acute colitis and colitis-associated colon cancer in mice.
Topics: Acute Disease; Animals; Azoxymethane; Bifidobacteriales Infections; Bifidobacterium; Blotting, Western; Carcinogens; Chronic Disease; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Immunoenzyme Techniques; Inflammation; Intestinal Mucosa; Lipopolysaccharides; Luciferases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Pitavastatin inhibits azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db obese mice.
Topics: Animals; Azoxymethane; Carcinogens; Cell Division; Colonic Neoplasms; Cytokines; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Precancerous Conditions; Quinolines | 2010 |
N-acetylcysteine attenuates cerebral complications of non-acetaminophen-induced acute liver failure in mice: antioxidant and anti-inflammatory mechanisms.
Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Azoxymethane; Brain Edema; Carcinogens; Cytokines; Disease Models, Animal; Hepatic Encephalopathy; Inflammation; Inflammation Mediators; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Oxidative Stress | 2010 |
Epimorphin deletion protects mice from inflammation-induced colon carcinogenesis and alters stem cell niche myofibroblast secretion.
Topics: Animals; Azoxymethane; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Epithelial Cells; Inflammation; Interleukin-6; Intestinal Mucosa; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; Sequence Deletion | 2010 |
Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis-associated tumorigenesis.
Topics: Animals; Azoxymethane; Blotting, Western; Carcinogens; Colitis, Ulcerative; Colonic Neoplasms; Dextran Sulfate; Enzyme-Linked Immunosorbent Assay; Humans; Immunoenzyme Techniques; Inflammation; Inflammation Mediators; Intestinal Mucosa; Mice; Mice, Transgenic; Microfilament Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Toll-Like Receptor 4 | 2011 |
Prevention of colitis-associated colorectal cancer with 8-hydroxydeoxyguanosine.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticarcinogenic Agents; Azoxymethane; Colitis; Colorectal Neoplasms; Deoxyguanosine; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation; Interleukin-10; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms; STAT3 Transcription Factor; Sulfates | 2011 |
Chronic psychosocial stress increases the risk for inflammation-related colon carcinogenesis in male mice.
Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Housing, Animal; Inflammation; Interferon-gamma; Male; Mice; Mice, Inbred C57BL; Social Dominance; Stress, Psychological | 2012 |
Effects of S-adenosylmethionine and methylthioadenosine on inflammation-induced colon cancer in mice.
Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Colonic Neoplasms; Dextran Sulfate; Inflammation; Interleukin-10; Interleukin-6; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-akt; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; STAT3 Transcription Factor; Transcriptional Activation; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2012 |
Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply.
Topics: Animals; Apoptosis; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Glutathione Peroxidase; Glutathione Transferase; Ileum; Inflammation; Isothiocyanates; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Selenium; Sulfoxides; Thiocyanates; Thioredoxin-Disulfide Reductase | 2012 |
Optical imaging of MMP expression and cancer progression in an inflammation-induced colon cancer model.
Topics: Animals; Azoxymethane; beta Catenin; Blotting, Western; Carbocyanines; Carcinogens; Colonic Neoplasms; Dextran Sulfate; Diagnostic Imaging; Disease Models, Animal; Disease Progression; Immunoenzyme Techniques; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Peptide Fragments | 2012 |
Glucagon-like peptide-2 increases dysplasia in rodent models of colon cancer.
Topics: Animals; Azoxymethane; beta Catenin; Blotting, Western; Carcinogens; Colitis; Colonic Neoplasms; Dextran Sulfate; Diet, High-Fat; Doublecortin Protein; Glucagon-Like Peptide 2; Imidazoles; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Inbred F344; Real-Time Polymerase Chain Reaction; RNA, Messenger | 2012 |
Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammation.
Topics: Animals; Azoxymethane; Carcinogens; Chromosome Mapping; Chromosomes, Mammalian; Colitis; Colorectal Neoplasms; Disease Resistance; Genetic Loci; Genetic Predisposition to Disease; Helicobacter hepaticus; Helicobacter Infections; Host-Pathogen Interactions; Humans; Immunity, Innate; Inflammation; Mice; Mice, 129 Strain; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Polymorphism, Single Nucleotide; Telomere | 2012 |
Dietary folate does not significantly affect the intestinal microbiome, inflammation or tumorigenesis in azoxymethane-dextran sodium sulphate-treated mice.
Topics: Animals; Azoxymethane; Biomarkers; Colitis, Ulcerative; Colon; Colonic Neoplasms; Dextran Sulfate; Dextrans; Diet; Disease Progression; Folic Acid; Inflammation; Male; Mice; Mice, Inbred C57BL; Microbiota; Neoplasms; RNA, Ribosomal, 16S; Sulfates | 2013 |
Organomagnesium suppresses inflammation-associated colon carcinogenesis in male Crj: CD-1 mice.
Topics: Adenocarcinoma; Adenoma; Animals; Apoptosis; Azoxymethane; Blotting, Western; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Humans; Immunoenzyme Techniques; Inflammation; Interferon-gamma; Interleukin-1beta; Interleukin-6; Magnesium Compounds; Male; Mice; Mice, Inbred ICR; Mitotic Index; Organometallic Compounds; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2013 |
Cocoa polyphenols prevent inflammation in the colon of azoxymethane-treated rats and in TNF-α-stimulated Caco-2 cells.
Topics: Animals; Anti-Inflammatory Agents; Azoxymethane; Biomarkers; Cacao; Colon; Diet; Down-Regulation; Humans; Inflammation; Inflammation Mediators; Male; MAP Kinase Kinase 4; Neoplasms; NF-kappa B; Phosphorylation; Phytotherapy; Plant Extracts; Polyphenols; Rats; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha | 2013 |
A polyacetylene-rich extract from Gymnaster koraiensis strongly inhibits colitis-associated colon cancer in mice.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Asteraceae; Azoxymethane; Cell Proliferation; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Inflammation; Liver; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Polyynes | 2013 |
Hesperidin alleviates oxidative stress and downregulates the expressions of proliferative and inflammatory markers in azoxymethane-induced experimental colon carcinogenesis in mice.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Azoxymethane; Biomarkers; Carcinogens; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Down-Regulation; Hesperidin; Inflammation; Male; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Proliferating Cell Nuclear Antigen | 2013 |
A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate.
Topics: Adenocarcinoma; Adenoma; Animals; Anticoagulants; Azoxymethane; beta Catenin; Carcinogens; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Dextran Sulfate; Disease Models, Animal; Inflammation; Injections, Intraperitoneal; Isoenzymes; Male; Mast Cells; Mice; Mice, Inbred ICR; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Trans-Activators; Tumor Suppressor Protein p53 | 2003 |
Liver receptor homolog 1 contributes to intestinal tumor formation through effects on cell cycle and inflammation.
Topics: Animals; Azoxymethane; Carcinogens; Cell Cycle; Disease Models, Animal; Female; Heterozygote; Humans; Inflammation; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Receptors, Cytoplasmic and Nuclear; Tumor Necrosis Factor-alpha | 2005 |
Beta-Catenin mutations in a mouse model of inflammation-related colon carcinogenesis induced by 1,2-dimethylhydrazine and dextran sodium sulfate.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Azoxymethane; beta Catenin; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Dextran Sulfate; Disease Models, Animal; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred ICR; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Trans-Activators | 2005 |
Polyethylene glycol reduces inflammation and aberrant crypt foci in carcinogen-initiated rats.
Topics: Administration, Oral; Animals; Azoxymethane; Caco-2 Cells; Carcinogens; Colon; Colonic Neoplasms; Humans; Inflammation; Male; Permeability; Polyethylene Glycols; Precancerous Conditions; Rats; Rats, Inbred F344; Solvents | 2005 |
Global gene expression analysis of the mouse colonic mucosa treated with azoxymethane and dextran sodium sulfate.
Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression; Gene Expression Profiling; Inflammation; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; Oligonucleotide Array Sequence Analysis | 2007 |
Colon cancer chemoprevention by a novel NO chimera that shows anti-inflammatory and antiproliferative activity in vitro and in vivo.
Topics: Animals; Apoptosis; Azoxymethane; Cell Count; Cell Line, Tumor; Cell Proliferation; Chemoprevention; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p27; Disulfides; DNA Damage; Enzyme Induction; Flow Cytometry; Humans; Inflammation; Male; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Poly(ADP-ribose) Polymerases; Precancerous Conditions; Rats; Rats, Inbred F344 | 2007 |
Cyclooxygenase 2 expression is increased in the stroma of colon carcinomas from IL-10(-/-) mice.
Topics: Animals; Azoxymethane; Colon; Colonic Neoplasms; Cyclooxygenase 2; In Situ Hybridization; Inflammation; Interleukin-10; Intestinal Mucosa; Isoenzymes; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stromal Cells | 2000 |