azoxymethane has been researched along with Experimental Neoplasms in 97 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (28.87) | 18.7374 |
| 1990's | 9 (9.28) | 18.2507 |
| 2000's | 11 (11.34) | 29.6817 |
| 2010's | 35 (36.08) | 24.3611 |
| 2020's | 14 (14.43) | 2.80 |
| Authors | Studies |
|---|---|
| Costa, P; de la Fuente, VG; Fernández, J; García, MTF; Ledesma, E; Lombó, F; Martínez-Camblor, P; Millán, E; Monte, J; Villar, CJ | 1 |
| Hirayama, D; Hirota, S; Horiuchi, H; Iida, T; Ikeuchi, H; Kawakami, K; Matsuura, M; Minami, N; Nagaishi, K; Nakase, H; Nojima, M; Shirakawa, R; Wagatsuma, K | 1 |
| Asch, AS; Kumar, G; Lightfoot, S; Madka, V; Mohammed, A; Pathuri, G; Rao, CV; Steele, VE; Zhang, Y | 1 |
| Chac, D; DePaolo, RW; Kim, JH; Kordahi, MC | 1 |
| Bautista, EJ; Chen, Y; Nakanishi, M; Qendro, V; Rosenberg, DW; Sodergren, E; Weinstock, GM | 1 |
| Deguchi, A; Kato, S; Kawanishi, S; Maebashi, U; Matsumoto, K; Morita, A; Motoyoshi, A; Nakahara, T; Nakamoto, T; Nishimura, K; Sueyoshi, M; Takata, K; Tominaga, M | 1 |
| Athavale, D; Bhat, MK; Chouhan, S; Deshmukh, B; Mayengbam, SS; Ramteke, P; Singh, S | 1 |
| Bonakdar, S; Emtyazjoo, M; Mostafavi, PG; Sahebi, Z | 1 |
| Ajani, JA; Anfossi, S; Bayraktar, R; Bhuvaneshwar, K; Burks, JK; Calin, GA; Chen, B; De Los Santos, MC; Dragomir, MP; Fabris, L; Ferracin, M; Fromm, B; Gagea, M; Girnita, L; Goel, A; Gusev, Y; Hanash, SM; Huo, L; Ivan, C; Ivkovic, TC; Katayama, H; Knutsen, E; Kopetz, S; Li, C; Li, Y; Ling, H; Liu, X; Matsuyama, T; Menter, D; Mimori, K; Multani, AS; Oki, E; Pardini, B; Parker-Thornburg, J; Reineke, LC; Sen, S; Shah, MY; Shen, P; Shimizu, M; Shimura, T; Slaby, O; Song, S; Syed, M; Taguchi, A; Tang, C; Uetake, H; Varani, G; Vasilescu, C | 1 |
| Chan, H; Chan, MTV; Coker, OO; Gin, T; Hu, W; Huang, D; Kang, W; Li, Q; Liu, WX; Liu, XD; Ng, SSM; Wong, SH; Wu, JL; Wu, WKK; Yu, J; Zeng, JD; Zhang, L; Zhang, Y; Zhao, LY | 1 |
| Bagni, C; Di Fusco, D; Di Grazia, A; Dinallo, V; Franzè, E; Laudisi, F; Marafini, I; Monteleone, G; Monteleone, I; Pedini, G; Rosina, E; Sica, G; Sileri, P; Stolfi, C | 1 |
| Bayrer, JR; Bisanz, JE; Bowman, C; Braverman, KN; Chawla, A; Escalante, V; Ganeshan, K; Man, K; Patterson, A; Tian, Y; Turnbaugh, PJ; Wang, B | 1 |
| Qiao, PF; Wang, FJ; Wang, Y; Zhang, HG; Zhao, ZX | 1 |
| Ando, S; Fukamachi, K; Iinuma, M; Matsumoto, H; Suzui, M; Yoshimoto, E | 1 |
| Ali, DA; Arab, HH; Ashour, AM; Kabel, AM | 1 |
| Berger, FG; Bridges, AE; Browning, DD; Hou, Y; Islam, BN; Kim, S; Kolhe, R; Rodriguez, PC; Sharman, SK; Singh, N; Sridhar, S; Trillo-Tinoco, J | 1 |
| Dunger, N; Endlicher, E; Goelder, S; Hartmann, A; Kunst, C; Lippert, E; Messmann, H; Obermeier, F; Rogler, G; Ruemmele, P | 1 |
| Agle, KA; Chen, X; Drobyski, WR; Huang, YW; Oshima, K; Pan, P; Wang, LS; Yearsley, MM; Yu, J; Zhang, J | 1 |
| Chevillard-Briet, M; Escaffit, F | 1 |
| Dubé, PE; Girish, N; Liu, CY; Polk, DB; Washington, MK | 1 |
| Ding, N; Gao, YH; Song, HL; Wang, M; Wen, H; Zhang, DM; Zhao, N | 1 |
| Attaix, D; Blas-Y-Estrada, F; Blot, A; Chantelauze, C; Chevolleau, S; Corpet, DE; Debrauwer, L; Dupuy, J; Durand, D; Guéraud, F; Kuhnle, GGC; Martin, OCB; Meunier, N; Naud, N; Pierre, FHF; Pujos-Guillot, E; Santé-Lhoutellier, V; Sayd, T; Schlich, P; Scislowski, V; Taché, S; Urbano, C; Viala, D | 1 |
| Callaway, ES; Chapkin, RS; Ivanov, I; Jayaprakasha, GK; Kim, E; Patil, BS; Turner, ND; Wright, GA; Zoh, RS | 1 |
| Arias, M; Castro, M; Pardo, J; Santiago, L | 1 |
| Chen, H; De Lisio, M; Emmons, R; Hernández-Saavedra, D; Kriska, A; Pan, YX; Xu, G | 1 |
| Awadallah, JR; El-Bana, MA; El-Daly, SM; Gamal-Eldeen, AM; Latif, YA; Medhat, D; Morsy, SM; Omara, EA | 1 |
| Andrés, E; Batlle, R; Berenguer-Llergo, A; Gonzalez, L; Gutierrez-Prat, N; Igea, A; Llonch, E; Nebreda, AR | 1 |
| Homanics, GE; Lazo, JS; Zimmerman, MW | 1 |
| Broaddus, RR; Gagea, M; Lee, SI; Liang, S; Manyam, GC; Morris, JS; Moussalli, MJ; Shureiqi, I; Wu, Y; Xu, M; Yu, J; Zuo, X | 1 |
| Adachi, Y; Arimura, Y; Fujimiya, M; Idogawa, M; Imai, K; Isshiki, H; Nagaishi, K; Naishiro, Y; Nakagaki, S; Nasuno, M; Onodera, K; Shinomura, Y; Suzuki, H; Watanabe, S; Yamashita, K | 1 |
| Arra, C; Barbieri, A; D'Orsi, L; Giorgio, E; Liguori, GL; Liguoro, A; Mancinelli, S; Palma, G | 1 |
| Chiou, LY; Chiou, YS; Ho, CT; Pan, MH; Tsai, ML | 1 |
| Biddick, L; Dai, W; Lightfoot, S; Rao, CV; Reddy, A; Sanghera, S; Yamada, HY; Zhang, Y | 1 |
| Matsui, H; Nagasaki, Y; Vong, LB; Yoshitomi, T | 1 |
| Cerdá-Nicolás, JM; Giner, E; Giner, RM; Recio, MC; Ríos, JL | 1 |
| Bialkowska, AB; Elkarim, EA; Ghaleb, AM; Yang, VW | 1 |
| Guo, Y; Huang, MT; Kong, AN; Li, W; Liu, Y; Su, ZY; Zhang, C | 1 |
| Barton, JK; Welge, WA | 1 |
| Cai, X; Cao, P; Chen, G; Cheng, X; Hu, C; Wang, M; Xu, Y; Yang, CS; Yang, Y | 1 |
| Chen, X; Li, F; Lin, L; Liu, S; Lou, X; Pan, Q; Shan, Q; Su, S; Wei, H; Wu, L; Xie, Y; Zhang, J; Zhu, Y | 1 |
| Begleiter, A; Bird, RP; Lefas, GM; Maksymiuk, AW; Sivananthan, K | 1 |
| Bouhadjar, M; Bousserouel, S; Gosse, F; Marescaux, J; Raul, F; Soler, L | 1 |
| Asano, M; Dawson, D; Guda, K; Iwakura, Y; Lawrence, E; Markowitz, SD; Satake, M; Sun, Q; Wang, Z; Watanabe, T; Wei, L; Willis, J; Yang, Z; Zhang, X; Zhao, Y; Zheng, W | 1 |
| Dinda, AK; Muralikrishnan, G; Shakeel, F | 1 |
| Belinsky, GS; Giardina, C; Rigatti, MJ; Rosenberg, DW; Verma, R | 1 |
| Bissonnette, M; Dougherty, U; Fichera, A; Goss, K; Hart, J; Joseph, L; Kupfer, S; Li, YC; Mustafi, R; Pekow, J; Robinson, V; Zhu, H | 1 |
| Backman, V; DelaCruz, M; Gomes, AJ; Roy, HK; Ruderman, S; Wali, RK | 1 |
| Dannenberg, AJ; Karoly, ED; Kopelovich, L; Montrose, DC; Subbaramaiah, K; Yantiss, RK; Zhou, XK | 1 |
| Ishikawa, H; Tanaka, T | 1 |
| Ji, P; Ouyang, N; Williams, JL | 1 |
| Bissonnette, M; Brasitus, T; Cohen, G; Hart, J; Joseph, L; Khare, S; Nguyen, L; Ramaswamy, A; Sitrin, M; Tretiakova, M; Wali, RK; Wang, J; Wen, M | 1 |
| Burnouf, D; Delincee, H; Gosse, F; Hartwig, A; Marchioni, E; Miesch, M; Raul, F; Werner, D | 1 |
| Das, S; Ghosh, S; Sengupta, A | 1 |
| Bhattacharya, S; Das, RK; Ghosh, S; Sengupta, A | 1 |
| Denda, A; Ichiba, M; Kuniyasu, H; Sasahira, T; Sasaki, T; Shimomoto, T; Shimura, H; Yoshida, K | 1 |
| Kamiya, K; Kashimoto, N; Kashiwabara, S; Uesaka, T; Wakabayashi, K; Watanabe, H | 1 |
| Fujii, K; Kuniyasu, H; Sasahira, T; Sasaki, T; Shimura, H | 1 |
| Costa, RH; Davidson, NO; Wang, IC; Yoder, HM; Yoshida, Y | 1 |
| Balik, E; Belizon, A; Ciau, N; Jain, S; Kirman, I; Remotti, H; Whelan, RL | 1 |
| Mori, H; Nicolais, M; Reddy, BS | 1 |
| Nigro, ND | 1 |
| Lijinsky, W; Reuber, MD; Saavedra, JE | 2 |
| Izbicki, JR; Izbicki, W; Kamran, D; Schmitz, R | 1 |
| Hioki, K; Hiramatsu, Y; Saito, K; Takada, H; Yamamoto, M; Yamamura, M | 1 |
| Shamsuddin, AK; Trump, BF | 1 |
| Hiramatsu, Y; Hirooka, T; Takada, H; Yamamoto, M | 1 |
| Mooney, B; Taylor, I | 1 |
| Bird, RP; Laferté, S; Moyana, T; Prokopishyn, NL | 1 |
| Magnuson, BA; Moyana, TN; Raju, RV; Sharma, RK | 1 |
| Fukutake, M; Ishida, K; Sugimura, T; Takahashi, M; Wakabayashi, K; Yokota, S | 1 |
| Hamid, R; Reddy, BS; Singh, J | 1 |
| Kelloff, G; Lubet, R; Rao, CV; Reddy, BS; Simi, B; Steele, V; Wang, CX | 1 |
| Fukuda, K; Sugimura, T; Takahashi, M; Wakabayashi, K | 1 |
| Ahnen, D; Driggers, L; Maltzman, T; Stephens, J; Whittington, J | 1 |
| Cooper, DP; Delker, DA; Papanikolaou, A; Povey, A; Rosenberg, DW; Shank, RC | 1 |
| Asamoto, M; Baba-Toriyama, H; Kakizoe, T; Kim, DJ; Kuhara, T; Moore, MA; Nakamura, J; Nishino, H; Sekine, K; Takasuka, N; Tsuda, H; Ushida, Y | 1 |
| Brtko, J; Macejová, D | 1 |
| Miyazawa, T; Moriya, M; Ohta, T; Shirasu, Y; Sugiyama, F; Watanabe, K; Watanabe, Y | 1 |
| Bull, AW; Campbell, RL; Klopfer, BA; Nigro, ND; Pak, MS | 1 |
| Kritchevsky, D; Reddy, BS; Watanabe, K; Weisburger, JH | 1 |
| Campbell, RL; Gantt, JS; Lin, YN; Nigro, ND; Singh, DV | 1 |
| Bauer, FL; Malt, RA; Ross, JS; Watkins, JB; Williamson, RC | 1 |
| Williamson, RC | 1 |
| Bull, AW; Hayden, MT; Nigro, ND; Soullier, BK; Wilson, PS | 1 |
| Brown, CA | 1 |
| Campbell, RL; Nigro, ND | 1 |
| Bauer, FL; Malt, RA; Oscarson, JE; Ross, JS; Williamson, RC | 1 |
| Reddy, BS; Watanabe, K; Weisburger, JH; Wong, CQ | 1 |
| Kroes, R; Weisburger, JH; Weiss, JW | 1 |
| Pozharisskiĭ, KM | 1 |
| Narisawa, T; Weisburger, JH; Wong, CQ | 1 |
| Sugimura, T | 1 |
| Campbell, RL; Lin, YN; Nigro, ND; Singh, DV | 1 |
| Berkvens, JM; Kroes, R; Weisburger, JH | 1 |
| Fiala, E | 1 |
| Kovatch, RM; Lijinsky, W; Riggs, CW | 1 |
3 review(s) available for azoxymethane and Experimental Neoplasms
| Article | Year |
|---|---|
Chemically induced carcinogenesis: a comparison of 1-methyl-1-nitrosourea, 7,12-dimethylbenzanthracene,diethylnitroso-amine and azoxymethan models (minireview).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Azoxymethane; Carcinogens; Diethylnitrosamine; Methylnitrosourea; Neoplasms, Experimental | 2001 |
Immune suppression and chemical carcinogenesis.
Topics: Animals; Antilymphocyte Serum; Azoxymethane; B-Lymphocytes; Carcinogens; Cocarcinogenesis; Cricetinae; Hydroxyacetylaminofluorene; Immunosuppression Therapy; Immunosuppressive Agents; Male; Mice; Neoplasms; Neoplasms, Experimental; Rats; T-Lymphocytes; Thymus Gland; Time Factors | 1975 |
[Successes of experimental oncology and problems of the study of the morphogenesis of tumors].
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Aflatoxins; Animals; Azoxymethane; Benzopyrenes; Brain Neoplasms; Carcinogens; Cricetinae; Dimethylhydrazines; Dogs; Esophageal Neoplasms; Ethionine; Ethylnitrosourea; Female; Hematopoietic System; Intestinal Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosamines; Nitroso Compounds; Nitrosoguanidines; o-Aminoazotoluene; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Skin Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms | 1975 |
1 trial(s) available for azoxymethane and Experimental Neoplasms
| Article | Year |
|---|---|
Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption.
Topics: Adult; Animals; Azoxymethane; Biomarkers; Carcinogenesis; Carcinogens; Colonic Neoplasms; Cooking; Cross-Over Studies; Feces; Female; Healthy Volunteers; Heme; Humans; Lipid Peroxidation; Male; Mice; Middle Aged; Neoplasms, Experimental; Rats; Rats, Inbred F344; Red Meat | 2018 |
93 other study(ies) available for azoxymethane and Experimental Neoplasms
| Article | Year |
|---|---|
Traditional Processed Meat Products Re-designed Towards Inulin-rich Functional Foods Reduce Polyps in Two Colorectal Cancer Animal Models.
Topics: Animals; Azoxymethane; Colon; Colorectal Neoplasms; Dextran Sulfate; Dietary Fiber; Fatty Acids, Volatile; Functional Food; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Intestinal Polyps; Inulin; Male; Meat Products; Metagenomics; Neoplasms, Experimental; Prebiotics; Rats; Swine | 2019 |
Down-regulation of RalGTPase-Activating Protein Promotes Colitis-Associated Cancer via NLRP3 Inflammasome Activation.
Topics: Animals; Azoxymethane; Colitis-Associated Neoplasms; Colon; Down-Regulation; GTPase-Activating Proteins; Humans; Inflammasomes; Intestinal Mucosa; Male; Mice; Mice, Knockout; Neoplasms, Experimental; NLR Family, Pyrin Domain-Containing 3 Protein; ral GTP-Binding Proteins | 2020 |
Bisphosphonates Zometa and Fosamax Synergize with Metformin to Prevent AOM-Induced Colon Cancer in F344 Rat Model.
Topics: Administration, Oral; Alendronate; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Male; Metformin; Neoplasms, Experimental; Rats; Rats, Inbred F344; Zoledronic Acid | 2020 |
Toll-like Receptor-6 Signaling Prevents Inflammation and Impacts Composition of the Microbiota During Inflammation-Induced Colorectal Cancer.
Topics: Animals; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Female; Gastrointestinal Microbiome; Humans; Immunity, Innate; Interleukin-10; Intestinal Mucosa; Lactobacillus; Mice; Mice, Knockout; Neoplasms, Experimental; Probiotics; Proteobacteria; Recombinant Proteins; Signal Transduction; Toll-Like Receptor 6 | 2020 |
Colon Cancer Prevention with Walnuts: A Longitudinal Study in Mice from the Perspective of a Gut Enterotype-like Cluster.
Topics: Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Diet, Western; Feces; Feeding Behavior; Female; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Juglans; Longitudinal Studies; Male; Mice; Neoplasms, Experimental; Nuts; Tumor Burden | 2020 |
Role of transient receptor potential vanilloid subtype 4 in the regulation of azoymethane/dextran sulphate sodium-induced colitis-associated cancer in mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Cell Proliferation; Chemokine CXCL2; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Progression; Human Umbilical Vein Endothelial Cells; Humans; Intestinal Mucosa; Macrophages; Male; Mice; Mice, Knockout; Neoplasms, Experimental; TRPV Cation Channels | 2020 |
Role of TNFα and leptin signaling in colon cancer incidence and tumor growth under obese phenotype.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Azoxymethane; Colonic Neoplasms; Colonic Polyps; Dextran Sulfate; Diet, High-Fat; Gene Knockdown Techniques; HCT116 Cells; Humans; Incidence; Leptin; Mice; Mice, Knockout; Mice, Obese; Neoplasms, Experimental; Obesity; Recombinant Proteins; Signal Transduction; Tumor Necrosis Factor-alpha; Tumor Suppressor Proteins; Up-Regulation | 2020 |
Promising Chemoprevention of Colonic Aberrant Crypt Foci by
Topics: Aberrant Crypt Foci; Animals; Antineoplastic Agents; Antioxidants; Azoxymethane; Biphenyl Compounds; Brachyura; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Injections, Intradermal; Male; Molecular Structure; Muscles; Neoplasms, Experimental; Picrates; Rats; Rats, Wistar; Structure-Activity Relationship; Tumor Cells, Cultured | 2020 |
The Long Noncoding RNA CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase B; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Chromosomal Instability; Colon; Colorectal Neoplasms; Cytogenetic Analysis; Dextrans; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Intestinal Mucosa; Male; Mice; Mice, Transgenic; Neoplasms, Experimental; Organoids; Primary Cell Culture; Proto-Oncogene Proteins c-myc; RNA-Binding Proteins; RNA, Long Noncoding; Signal Transduction | 2020 |
Streptococcus thermophilus Inhibits Colorectal Tumorigenesis Through Secreting β-Galactosidase.
Topics: Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; Bacterial Proteins; beta-Galactosidase; Cell Line, Tumor; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; Humans; Intestinal Mucosa; Male; Mice; Mice, Transgenic; Neoplasms, Experimental; Probiotics; Streptococcus thermophilus | 2021 |
The Fragile X Mental Retardation Protein Regulates RIPK1 and Colorectal Cancer Resistance to Necroptosis.
Topics: Animals; Azoxymethane; Carcinogenesis; Case-Control Studies; Cell Culture Techniques; Cell Line, Tumor; Colon; Colorectal Neoplasms; Datasets as Topic; Disease-Free Survival; Fragile X Mental Retardation Protein; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Healthy Volunteers; Humans; Male; Mice; Mice, Knockout; Necroptosis; Neoplasm Recurrence, Local; Neoplasms, Experimental; Organoids; Prognosis; Receptor-Interacting Protein Serine-Threonine Kinases | 2021 |
A thermogenic fat-epithelium cell axis regulates intestinal disease tolerance.
Topics: Adipocytes; Adipose Tissue, Brown; Animals; Azoxymethane; Cell Communication; Citrobacter rodentium; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Resistance; Enterobacteriaceae Infections; Epithelial Cells; Female; Humans; Intestinal Mucosa; Male; Mice; Neoplasms, Experimental; Thermogenesis | 2020 |
lncRNA GAS5 inhibits malignant progression by regulating macroautophagy and forms a negative feedback regulatory loop with the miR‑34a/mTOR/SIRT1 pathway in colorectal cancer.
Topics: Aged; Animals; Azoxymethane; Cell Line, Tumor; Colon; Colorectal Neoplasms; Feedback, Physiological; Female; Gene Expression Regulation, Neoplastic; Humans; Macroautophagy; Male; MicroRNAs; Middle Aged; Neoplasms, Experimental; Rats; RNA, Long Noncoding; Signal Transduction; Sirolimus; Sirtuin 1; TOR Serine-Threonine Kinases | 2021 |
Palmitoyl piperidinopiperidine, a novel derivative of 10‑hydroxy‑2‑decenoic acid, as a potent and selective anticancer agent against human colon carcinoma cell lines.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Carcinogens; Carcinoma; Cell Line, Tumor; Chick Embryo; Chorioallantoic Membrane; Colonic Neoplasms; Fatty Acids, Monounsaturated; Female; Humans; Inhibitory Concentration 50; Male; Mice; Molecular Docking Simulation; Neoplasms, Experimental; Neovascularization, Pathologic; Rats; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2021 |
The immunomodulatory effects of topiramate on azoxymethane-induced colon carcinogenesis in rats: The role of the inflammatory cascade, vascular endothelial growth factor, AKT/mTOR/MAP kinase signaling and the apoptotic markers.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogenesis; Colon; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Intestinal Mucosa; Male; MAP Kinase Signaling System; Neoplasms, Experimental; Proto-Oncogene Proteins c-akt; Rats; Topiramate; TOR Serine-Threonine Kinases; Tumor Microenvironment | 2021 |
Sildenafil Suppresses Inflammation-Driven Colorectal Cancer in Mice.
Topics: Administration, Oral; Animals; Apoptosis; Azoxymethane; Carcinogenesis; Colitis; Colon; Colorectal Neoplasms; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dextran Sulfate; Humans; Immunohistochemistry; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Phosphodiesterase 5 Inhibitors; Polyps; Signal Transduction; Sildenafil Citrate | 2017 |
Anthocyanins Prevent Colorectal Cancer Development in a Mouse Model.
Topics: Animals; Anthocyanins; Azoxymethane; Carcinoma in Situ; Colon; Colonic Neoplasms; Colonoscopy; Dextran Sulfate; Drug Screening Assays, Antitumor; Female; Mice, Inbred BALB C; Neoplasms, Experimental; Phytotherapy | 2017 |
Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colitis; Colonic Neoplasms; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dextran Sulfate; Disease Progression; Epigenesis, Genetic; Histone Deacetylases; Homeostasis; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Neutrophils; Receptors, G-Protein-Coupled | 2018 |
Methods for In Vivo Functional Studies of Chromatin-Modifying Enzymes in Early Steps of Colon Carcinogenesis.
Topics: Animals; Azoxymethane; Benzeneacetamides; Carcinogenesis; Chromatin; Colon; Colorectal Neoplasms; Dextran Sulfate; DNA Helicases; DNA-Binding Proteins; Histones; Humans; Intestinal Mucosa; Lysine Acetyltransferase 5; Mice; Mice, Transgenic; Neoplasms, Experimental; Pyridines; Trans-Activators; Transcription Factors; Wnt Signaling Pathway | 2018 |
Pharmacological activation of epidermal growth factor receptor signaling inhibits colitis-associated cancer in mice.
Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Dextran Sulfate; Epidermal Growth Factor; ErbB Receptors; Mice; Neoplasm Proteins; Neoplasms, Experimental; Signal Transduction | 2018 |
Peritoneal lavage with povidone-iodine solution in colorectal cancer-induced rats.
Topics: Acidosis; Animals; Anti-Infective Agents, Local; Azoxymethane; Bacterial Translocation; Colorectal Neoplasms; Dextran Sulfate; Endotoxins; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Male; Microscopy, Electron, Transmission; Neoplasms, Experimental; Peritoneal Absorption; Peritoneal Lavage; Permeability; Povidone-Iodine; Rats; Rats, Sprague-Dawley; Shock, Septic; Tight Junctions | 2018 |
Establishment of a multicomponent dietary bioactive human equivalent dose to delete damaged Lgr5+ stem cells using a mouse colon tumor initiation model.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Curcumin; Dietary Supplements; Dose-Response Relationship, Drug; Fatty Acids, Omega-3; Female; Gene Knock-In Techniques; Humans; Intestinal Mucosa; Male; Mice; Mice, Transgenic; Neoplasms, Experimental; Neoplastic Stem Cells; Receptors, G-Protein-Coupled | 2019 |
Mouse Model of Colitis-Associated Colorectal Cancer (CAC): Isolation and Characterization of Mucosal-Associated Lymphoid Cells.
Topics: Animals; Azoxymethane; Cell Separation; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Colitis, Ulcerative; Colon; Colorectal Neoplasms; Dextran Sulfate; Flow Cytometry; Humans; Intestinal Mucosa; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms, Experimental | 2019 |
Effects of obesity and exercise on colon cancer induction and hematopoiesis in mice.
Topics: Adipose Tissue; Animals; Azoxymethane; Bone Marrow; Carcinogens; Colonic Neoplasms; Diet, High-Fat; Hematopoiesis; Hematopoietic Stem Cells; Inflammation; Mice; Myeloid Progenitor Cells; Neoplasms, Experimental; Obesity; Physical Conditioning, Animal; Proteomics; Random Allocation; Sedentary Behavior | 2019 |
The diagnostic efficacy of circulating miRNAs in monitoring the early development of colitis-induced colorectal cancer.
Topics: Animals; Azoxymethane; Circulating MicroRNA; Colitis; Colorectal Neoplasms; Dextran Sulfate; Gene Expression Regulation, Neoplastic; Male; Mice; Neoplasms, Experimental | 2019 |
Regulation of tumor angiogenesis and mesenchymal-endothelial transition by p38α through TGF-β and JNK signaling.
Topics: Animals; Azoxymethane; Carcinogens; Cell Proliferation; Cell Transdifferentiation; Colonic Neoplasms; Endothelial Cells; Endothelium, Vascular; Epithelial-Mesenchymal Transition; Gene Knockdown Techniques; HT29 Cells; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase 14; Neoplasms, Experimental; Neovascularization, Pathologic; RNA, Small Interfering; Transforming Growth Factor beta | 2019 |
Targeted deletion of the metastasis-associated phosphatase Ptp4a3 (PRL-3) suppresses murine colon cancer.
Topics: Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Dextran Sulfate; Gene Deletion; Humans; Immediate-Early Proteins; Intestinal Mucosa; Mice; Mice, Knockout; Neoplasm Metastasis; Neoplasms, Experimental; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-myc | 2013 |
Potentiation of colon cancer susceptibility in mice by colonic epithelial PPAR-δ/β overexpression.
Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Disease Susceptibility; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; PPAR-beta; Receptors, Cytoplasmic and Nuclear; Up-Regulation | 2014 |
Mesenchymal stem cells cancel azoxymethane-induced tumor initiation.
Topics: Animals; Azoxymethane; Carcinogens; Cells, Cultured; Coculture Techniques; Colonic Neoplasms; G1 Phase Cell Cycle Checkpoints; Humans; Mesenchymal Stem Cells; Neoplasms, Experimental; Rats; Rats, Inbred Lew; Transforming Growth Factor beta; Wnt Signaling Pathway | 2014 |
Cripto haploinsufficiency affects in vivo colon tumor development.
Topics: Animals; Apoptosis; Azoxymethane; Colonic Neoplasms; Endoplasmic Reticulum Chaperone BiP; Epidermal Growth Factor; Female; Gene Expression Regulation, Neoplastic; Haploinsufficiency; Heat-Shock Proteins; Membrane Glycoproteins; Mice; Neoplasm Proteins; Neoplasms, Experimental | 2014 |
Garcinol suppresses inflammation-associated colon carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; beta Catenin; Colitis; Colonic Neoplasms; Dextran Sulfate; Hepatitis; Inflammation Mediators; Lipid Metabolism; Male; Mice, Inbred ICR; Neoplasms, Experimental; Signal Transduction; Terpenes | 2014 |
Antagonizing pathways leading to differential dynamics in colon carcinogenesis in Shugoshin1 (Sgo1)-haploinsufficient chromosome instability model.
Topics: Animals; Azoxymethane; Cell Cycle Proteins; Cell Line, Tumor; Chromosomal Instability; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Haploinsufficiency; Humans; Mice; Neoplasms, Experimental; Oncogenes; Signal Transduction | 2016 |
Development of an oral nanotherapeutics using redox nanoparticles for treatment of colitis-associated colon cancer.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Azoxymethane; Camptothecin; Cell Line, Tumor; Colitis; Colonic Neoplasms; Dextrans; Drug Delivery Systems; Drug Screening Assays, Antitumor; Endoscopy; Free Radical Scavengers; Inflammation; Irinotecan; Male; Mice; Mice, Inbred ICR; Nanomedicine; Nanoparticles; Neoplasms, Experimental; Nitrogen Oxides; Oxidation-Reduction; Reactive Oxygen Species; Sulfates | 2015 |
Chemopreventive effect of oleuropein in colitis-associated colorectal cancer in c57bl/6 mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Cell Proliferation; Colitis; Colon; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Female; Iridoid Glucosides; Iridoids; Mice, Inbred C57BL; Neoplasms, Experimental; Th17 Cells | 2016 |
KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis.
Topics: Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; Cells, Cultured; Colonic Neoplasms; Epigenesis, Genetic; Gene Deletion; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Intestinal Mucosa; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice; Mutation; Neoplasms, Experimental; TOR Serine-Threonine Kinases | 2016 |
The epigenetic effects of aspirin: the modification of histone H3 lysine 27 acetylation in the prevention of colon carcinogenesis in azoxymethane- and dextran sulfate sodium-treated CF-1 mice.
Topics: Animals; Anticarcinogenic Agents; Aspirin; Azoxymethane; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Epigenesis, Genetic; Histone Deacetylases; Histones; Lysine; Male; Mice, Inbred Strains; Neoplasms, Experimental; Nitric Oxide Synthase Type II | 2016 |
In vivo endoscopic Doppler optical coherence tomography imaging of the colon.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colonic Neoplasms; Disease Models, Animal; Endosonography; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Sensitivity and Specificity; Tomography, Optical Coherence | 2017 |
Protective effects of Huangqin Decoction against ulcerative colitis and associated cancer in mice.
Topics: Animals; Antioxidants; Azoxymethane; Chromatography, High Pressure Liquid; Colitis, Ulcerative; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Drugs, Chinese Herbal; Flavanones; Inflammation; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Oxidative Stress; Plant Extracts; Scutellaria baicalensis | 2016 |
Genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Exome Sequencing; Genetic Variation; Humans; Male; Mice, Inbred C57BL; Mutation; Neoplasms, Experimental | 2017 |
Inhibition of colon carcinogenesis by post-initiation induction of NQO1 in Sprague-Dawley rats.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Enzyme Induction; Glucuronosyltransferase; Glutathione Transferase; Intestinal Mucosa; Male; NAD(P)H Dehydrogenase (Quinone); Neoplasms, Experimental; Precancerous Conditions; Pyrazines; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes; Time Factors | 2009 |
Long-term administration of aspirin inhibits tumour formation and triggers anti-neoplastic molecular changes in a pre-clinical model of colon carcinogenesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Azoxymethane; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Colonic Neoplasms; Drug Evaluation, Preclinical; Gene Expression Regulation, Neoplastic; Immunity, Innate; Inflammation Mediators; Male; Neoplasms, Experimental; Rats; Rats, Wistar; Time Factors | 2010 |
Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T.
Topics: Animals; Azoxymethane; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Female; HCT116 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mutation; Neoplasms, Experimental; Paxillin; Phosphorylation; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Substrate Specificity; Transfection; Transplantation, Heterologous; Tyrosine | 2010 |
Immunomodulatory effects of Withania somnifera on azoxymethane induced experimental colon cancer in mice.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Colon; Colonic Neoplasms; Immunocompetence; Immunoglobulins; Immunomodulation; Mice; Neoplasms, Experimental; Plant Extracts; Plant Roots; Withania | 2010 |
Pharmacological inhibition of Mdm2 triggers growth arrest and promotes DNA breakage in mouse colon tumors and human colon cancer cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azoxymethane; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; DNA Damage; Doxorubicin; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Imidazoles; Mice; Neoplasms, Experimental; Piperazines; Proto-Oncogene Proteins c-mdm2; Tumor Suppressor Protein p53 | 2012 |
EGFR signals downregulate tumor suppressors miR-143 and miR-145 in Western diet-promoted murine colon cancer: role of G1 regulators.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azoxymethane; Cetuximab; Colitis, Ulcerative; Colonic Neoplasms; Dextran Sulfate; Diet; Down-Regulation; ErbB Receptors; G1 Phase; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; HCT116 Cells; Humans; Mice; MicroRNAs; Neoplasms, Experimental; Rats; Signal Transduction | 2011 |
In vivo measurement of the shape of the tissue-refractive-index correlation function and its application to detection of colorectal field carcinogenesis.
Topics: Algorithms; Animals; Azoxymethane; Case-Control Studies; Colonic Neoplasms; Colonoscopy; Male; Monte Carlo Method; Neoplasms, Experimental; Rats; Rats, Inbred F344; Refractometry; Spectrum Analysis | 2012 |
Metabolic profiling, a noninvasive approach for the detection of experimental colorectal neoplasia.
Topics: Animals; Azoxymethane; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Feces; Gas Chromatography-Mass Spectrometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Metabolome; Metabolomics; Mice; Models, Statistical; Neoplasms, Experimental; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors | 2012 |
Mast cells and inflammation-associated colorectal carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogens; Colon; Colorectal Neoplasms; Cytokines; Inflammatory Bowel Diseases; Macrophages; Male; Mast Cells; Mice; Mice, Mutant Strains; Neoplasm Proteins; Neoplasms, Experimental | 2013 |
A novel NSAID derivative, phospho-ibuprofen, prevents AOM-induced colon cancer in rats.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Ibuprofen; Neoplasms, Experimental; NF-kappa B; Organophosphates; Rats | 2013 |
Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: roles of cyclin D1 and E-cadherin.
Topics: Animals; Azoxymethane; Base Sequence; Biomarkers, Tumor; Biopsy, Needle; Blotting, Western; Cadherins; Cell Division; Cholecalciferol; Colonic Neoplasms; Cyclin D1; Disease Models, Animal; Immunohistochemistry; Injections, Intraperitoneal; Intestinal Mucosa; Male; Molecular Sequence Data; Neoplasms, Experimental; Polymerase Chain Reaction; Random Allocation; Rats; Rats, Inbred F344; Reference Values; RNA, Messenger; Sensitivity and Specificity; Ursodeoxycholic Acid | 2002 |
Food-borne radiolytic compounds (2-alkylcyclobutanones)may promote experimental colon carcinogenesis.
Topics: Analysis of Variance; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Cyclobutanes; Disease Models, Animal; Food Irradiation; Male; Neoplasms, Experimental; Rats; Rats, Wistar | 2002 |
Tea can protect against aberrant crypt foci formation during azoxymethane induced rat colon carcinogenesis.
Topics: Administration, Oral; Animals; Antioxidants; Azoxymethane; Biological Assay; Carcinogens; Colonic Neoplasms; Flavonoids; Glutathione Peroxidase; Glutathione Transferase; Lipid Peroxidation; Male; Neoplasms, Experimental; Phenols; Polyphenols; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Tea; Time Factors | 2003 |
Inhibition of azoxymethane-induced aberrant crypt foci in rat by diphenylmethyl selenocyanate through downregulation of COX-2 and modulation of glutathione-S-transferase and lipid peroxidation.
Topics: Animals; Azoxymethane; Blotting, Western; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Lipid Peroxidation; Liver; Male; Models, Chemical; Neoplasms, Experimental; Organoselenium Compounds; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Selenium; Time Factors | 2005 |
Inhibitory effect of linoleic acid on transformation of IEC6 intestinal cells by in vitro azoxymethane treatment.
Topics: Animals; Arachidonate 15-Lipoxygenase; Azoxymethane; bcl-2-Associated X Protein; Carcinogens; Cell Transformation, Neoplastic; Cyclooxygenase 2; Cytochrome P-450 CYP2E1; DNA Damage; ErbB Receptors; In Vitro Techniques; Intestinal Mucosa; Ligands; Linoleic Acid; Lipoxygenase Inhibitors; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Oligodeoxyribonucleotides, Antisense; Phosphorylation; PPAR gamma; Rats | 2006 |
Tumor induction by azoxymethane (AOM) and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in F344 rat gastric mucosa featuring intestinal metaplasia caused by X-irradiation.
Topics: Animals; Azoxymethane; Body Weight; Carcinogens; Carcinoma, Signet Ring Cell; Cytoplasm; Gastric Mucosa; Imidazoles; Immunohistochemistry; Intestines; Male; Metaplasia; Mutagens; Neoplasms, Experimental; Organ Size; Rats; Rats, Inbred F344; Stomach Neoplasms; Time Factors; X-Rays | 2005 |
High concentration of deoxycholic acid abrogates in vitro transformation of IEC6 intestinal cells by azoxymethane.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Carcinogens; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Comet Assay; Cytochrome P-450 CYP2E1; Deoxycholic Acid; In Vitro Techniques; Mice; Mice, Nude; Neoplasms, Experimental; Rats | 2005 |
The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Azoxymethane; Biomarkers, Tumor; Bromodeoxyuridine; Carcinogens; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin A; Cyclin A2; Cyclin B; Cyclin B1; Dextran Sulfate; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubule-Associated Proteins; Neoplasm Proteins; Neoplasms, Experimental; Polymerase Chain Reaction; Proteins; Repressor Proteins; RNA, Neoplasm; RNA, Small Interfering; RNA, Untranslated; Survivin; TCF Transcription Factors; Transcription Factor 7-Like 2 Protein | 2007 |
Insulin-like growth factor binding protein-3 inhibits colitis-induced carcinogenesis.
Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Disease Progression; Female; Follow-Up Studies; Insulin-Like Growth Factor Binding Protein 3; Mice; Mice, Transgenic; Neoplasms, Experimental; Treatment Outcome | 2007 |
Effect of dietary wheat bran and dehydrated citrus fiber on azoxymethane-induced intestinal carcinogenesis in Fischer 344 rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azo Compounds; Azoxymethane; Cellulose; Colonic Neoplasms; Dietary Fiber; Edible Grain; Fruit; Intestinal Neoplasms; Male; Neoplasms, Experimental; Rats; Rats, Inbred F344 | 1981 |
Animal studies implicating fat and fecal steroids in intestinal cancer.
Topics: Animals; Azoxymethane; Cattle; Cocarcinogenesis; Colon; Dietary Fats; Dietary Fiber; Feces; Humans; Intestinal Neoplasms; Male; Meat; Neoplasms, Experimental; Rats; Steroids | 1981 |
The effect of deuterium substitution on carcinogenesis by azoxymethane.
Topics: Animals; Azo Compounds; Azoxymethane; Biotransformation; Colonic Neoplasms; Deuterium; Kidney Neoplasms; Liver Neoplasms; Male; Neoplasms, Experimental; Oxidation-Reduction; Rats; Rats, Inbred F344; Structure-Activity Relationship | 1984 |
Androgens as promoters of colon carcinogenesis.
Topics: Androgens; Animals; Azoxymethane; Carcinoembryonic Antigen; Castration; Colonic Neoplasms; Male; Neoplasms, Experimental; Rats; Rats, Inbred F344 | 1983 |
Effect of dietary cholesterol on azoxymethane-induced colon carcinogenesis in rats.
Topics: Animals; Azo Compounds; Azoxymethane; Bile Acids and Salts; Cholesterol; Cholesterol, Dietary; Cocarcinogenesis; Colonic Neoplasms; Feces; Male; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Sterols | 1983 |
Colon epithelium. II. In vivo studies of colon carcinogenesis. Light microscopic, histochemical, and ultrastructural studies of histogenesis of azoxymethane-induced colon carcinomas in Fischer 344 rats.
Topics: Animals; Azo Compounds; Azoxymethane; Carcinoma; Colonic Neoplasms; Epithelium; Intestinal Mucosa; Male; Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Inbred F344 | 1981 |
Effect of beta-glucuronidase inhibitor on azoxymethane-induced colonic carcinogenesis in rats.
Topics: Animals; Azo Compounds; Azoxymethane; Benzylidene Compounds; Biotransformation; Cocarcinogenesis; Colonic Neoplasms; Glucuronidase; Intestinal Mucosa; Neoplasms, Experimental; Rats | 1982 |
The effect of hepatic arterial ligation on spontaneously developing colorectal liver metastases in the rat.
Topics: Animals; Azoxymethane; Colonic Neoplasms; Hepatic Artery; Ligation; Liver Circulation; Liver Neoplasms; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Rectal Neoplasms | 1982 |
Monoclonal antibody recognizing a determinant on type 2 chain blood group A and B oligosaccharides detects oncodevelopmental changes in azoxymethane-induced rat colon tumors and human colon cancer cell lines.
Topics: ABO Blood-Group System; Animals; Antibodies, Monoclonal; Azoxymethane; Blotting, Western; Carbohydrate Sequence; Colonic Neoplasms; Epitopes; Female; Glycoproteins; Humans; Immunohistochemistry; Mice; Molecular Sequence Data; Neoplasms, Experimental; Oligosaccharides; Rats; Rats, Sprague-Dawley | 1995 |
Increased N-myristoyltransferase activity observed in rat and human colonic tumors.
Topics: Acyltransferases; Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Humans; Male; Neoplasms, Experimental; Protein Processing, Post-Translational; Random Allocation; Rats; Rats, Sprague-Dawley | 1995 |
Suppression of azoxymethane-induced aberrant crypt foci in rat colon by nimesulide, a selective inhibitor of cyclooxygenase 2.
Topics: Animals; Azoxymethane; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Intestinal Mucosa; Isoenzymes; Male; Neoplasms, Experimental; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Sulfonamides | 1996 |
Dietary fat and colon cancer: modulating effect of types and amount of dietary fat on ras-p21 function during promotion and progression stages of colon cancer.
Topics: Animals; Azoxymethane; Blotting, Western; Carcinogens; Colon; Colonic Neoplasms; Corn Oil; Dietary Fats; Fish Oils; Intestinal Mucosa; Male; Neoplasms, Experimental; Proto-Oncogene Proteins p21(ras); Rats; Rats, Inbred F344 | 1997 |
Enhancement of experimental colon cancer by genistein.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Dinoprost; Drug Synergism; F2-Isoprostanes; Genistein; Hydroxyprostaglandin Dehydrogenases; Intestinal Mucosa; Isoflavones; Male; Neoplasms, Experimental; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344 | 1997 |
Beta-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors.
Topics: Adenocarcinoma; Animals; Azoxymethane; Base Sequence; beta Catenin; Carcinogens; Colonic Neoplasms; Cytoskeletal Proteins; Male; Molecular Sequence Data; Neoplasm Proteins; Neoplasms, Experimental; Point Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Trans-Activators | 1998 |
AOM-induced mouse colon tumors do not express full-length APC protein.
Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; Carcinoma in Situ; Colonic Neoplasms; Cytoskeletal Proteins; Female; Fluorescent Antibody Technique, Indirect; Intestinal Polyps; Male; Mice; Molecular Weight; Mutation; Neoplasm Proteins; Neoplasms, Experimental | 1997 |
Initial levels of azoxymethane-induced DNA methyl adducts are not predictive of tumor susceptibility in inbred mice.
Topics: Animals; Azoxymethane; Biotransformation; Carcinogens; Cattle; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Guanine; Immunoblotting; Male; Methylnitrosourea; Mice; Mice, Inbred AKR; Mice, Inbred Strains; Neoplasms, Experimental; Predictive Value of Tests | 1998 |
Inhibition of azoxymethane initiated colon tumor and aberrant crypt foci development by bovine lactoferrin administration in F344 rats.
Topics: Animals; Azoxymethane; Carcinogens; Cattle; Colon; Colonic Neoplasms; Lactoferrin; Male; Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Inbred F344 | 1998 |
Inhibitors for the mutagenicities of colon carcinogens, 1,2-dimethylhydrazine and azoxymethane, in the host-mediated assay.
Topics: Aminoacetonitrile; Animals; Azo Compounds; Azoxymethane; Carbon Disulfide; Colonic Neoplasms; Dimethylhydrazines; Disulfiram; Ditiocarb; Drug Evaluation, Preclinical; Male; Maneb; Methylhydrazines; Mice; Mutagens; Neoplasms, Experimental; Pyrazoles | 1979 |
Effect of dietary fiber on azoxymethane-induced intestinal carcinogenesis in rats.
Topics: Animals; Azo Compounds; Azoxymethane; Bile Acids and Salts; Body Weight; Cellulose; Cholestanols; Dietary Fats; Dietary Fiber; Energy Intake; Feces; Intestinal Neoplasms; Male; Neoplasms, Experimental; Rats | 1979 |
Effect of dietary alfalfa, pectin, and wheat bran on azoxymethane-or methylnitrosourea-induced colon carcinogenesis in F344 rats.
Topics: Animals; Azoxymethane; Cellulose; Colonic Neoplasms; Dietary Fiber; Female; Medicago sativa; Methylnitrosourea; Neoplasms, Experimental; Pectins; Rats; Rats, Inbred F344; Triticum | 1979 |
A comparison of the effects of the hypocholesteremic agents, cholestyramine and candicidin, on the induction of intestinal tumors in rats by azoxymethane.
Topics: Animals; Antifungal Agents; Azo Compounds; Azoxymethane; Bile Acids and Salts; Body Weight; Candicidin; Cholestanol; Cholesterol; Cholestyramine Resin; Drug Synergism; Feces; Intestinal Neoplasms; Intestine, Large; Intestine, Small; Lipid Metabolism; Male; Neoplasm Metastasis; Neoplasms, Experimental; Rats | 1977 |
Enhanced colonic carcinogenesis with azoxymethane in rats after pancreaticobiliary diversion to mid small bowel.
Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Ampulla of Vater; Animals; Azo Compounds; Azoxymethane; Bile; Bile Acids and Salts; Body Weight; Carcinoma, Squamous Cell; Colonic Neoplasms; DNA; Duodenal Neoplasms; Intestine, Small; Male; Neoplasms, Experimental; Pancreatic Juice; Rats; RNA | 1979 |
Hyperplasia and neoplasia of the intestinal tract.
Topics: Adaptation, Physiological; Animals; Azoxymethane; Cell Division; DNA; Intestinal Mucosa; Intestinal Neoplasms; Intestines; Male; Methods; Neoplasms, Experimental; Postoperative Complications; Precancerous Conditions; Rats; RNA; Time Factors | 1979 |
Promotion of azoxymethane-induced intestinal cancer by high-fat diet in rats.
Topics: Animals; Azo Compounds; Azoxymethane; Body Weight; Cocarcinogenesis; Dietary Fats; Energy Intake; Intestinal Neoplasms; Intestine, Large; Intestine, Small; Neoplasms, Experimental; Rats | 1979 |
The cytochemical demonstration of beta-glucuronidase in colon neoplasms of rats exposed to azoxymethane.
Topics: Adenocarcinoma; Animals; Azo Compounds; Azoxymethane; Colon; Colonic Neoplasms; Glucuronidase; Intestinal Mucosa; Intestinal Polyps; Lymphatic Metastasis; Male; Neoplasms, Experimental; Rats | 1978 |
Inhibition of azoxymethane-induced intestinal cancer by disulfiram.
Topics: Animals; Azo Compounds; Azoxymethane; Biotransformation; Colon; Colostomy; Disulfiram; Intestinal Neoplasms; Intestine, Small; Male; Neoplasms, Experimental; Rats | 1978 |
Promotion of azoxymethane-induced colonic neoplasia by resection of the proximal small bowel.
Topics: Adaptation, Physiological; Animals; Azo Compounds; Azoxymethane; Colonic Neoplasms; DNA; Hyperplasia; Ileum; Intestinal Mucosa; Intestine, Small; Jejunum; Male; Neoplasm Metastasis; Neoplasms, Experimental; Rats; RNA | 1978 |
Effect of dietary undegraded carrageenan on colon carcinogenesis in F344 rats treated with azoxymethane or methylnitrosourea.
Topics: Animals; Azo Compounds; Azoxymethane; Carrageenan; Cellulose; Colonic Neoplasms; Dietary Fiber; Female; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rectal Neoplasms | 1978 |
Azoxymethane-induced liver hemangiosarcomas in inbred strain-2 guinea pigs.
Topics: Animals; Azo Compounds; Azoxymethane; Guinea Pigs; Hemangiosarcoma; Injections; Liver Neoplasms; Neoplasms, Experimental; Rectum | 1976 |
Experimental tumors in digestive organs.
Topics: Animals; Azoxymethane; Benz(a)Anthracenes; Colonic Neoplasms; Cricetinae; Dogs; Duodenal Neoplasms; Esophageal Neoplasms; Gastrointestinal Neoplasms; Guinea Pigs; Methylnitronitrosoguanidine; Mice; Neoplasms, Experimental; Nitrites; Nitrosamines; Nitrosoguanidines; Pancreatic Neoplasms; Rabbits; Rats; Stomach Neoplasms | 1976 |
Effect of diet high in beef fat on the composition of fecal bile acids during intestinal carcinogenesis in the rat.
Topics: Animals; Azoxymethane; Bile Acids and Salts; Cholesterol; Cholic Acids; Cocarcinogenesis; Deoxycholic Acid; Dietary Fats; Fatty Acids; Feces; Intestinal Neoplasms; Male; Meat; Neoplasms, Experimental; Rats | 1976 |
Immunosuppression in primary liver and colon tumor induction with N-hydroxy-N-2-fluorenylacetamide and azoxymethane.
Topics: 2-Acetylaminofluorene; Animals; Antilymphocyte Serum; Azoxymethane; Colonic Neoplasms; Hemangiosarcoma; Immunosuppression Therapy; Liver Neoplasms; Male; Neoplasms, Experimental; Rats; Sarcoma, Experimental; Time Factors | 1975 |
Investigations into the metabolism and mode of action of the colon carcinogen 1, 2-dimethylhydrazine.
Topics: Animals; Azo Compounds; Azoxymethane; Chromatography, Gel; Chromatography, Thin Layer; Colonic Neoplasms; Dimethylhydrazines; Hydrazines; Methane; Methylazoxymethanol Acetate; Neoplasms, Experimental | 1975 |
Carcinogenesis by nitrosodialkylamines and azoxyalkanes given by gavage to rats and hamsters.
Topics: Administration, Oral; Alkylating Agents; Animals; Azo Compounds; Azoxymethane; Carcinogens; Cricetinae; Intubation; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344; Species Specificity | 1987 |
Organ-specific carcinogenesis in rats by methyl- and ethylazoxyalkanes.
Topics: Animals; Azo Compounds; Azoxymethane; Carcinogens; Indicators and Reagents; Liver Neoplasms; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Neoplasms, Experimental; Rats; Rats, Inbred F344; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1985 |