Page last updated: 2024-08-23

azoxymethane and Colorectal Cancer

azoxymethane has been researched along with Colorectal Cancer in 348 studies

Research

Studies (348)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (5.17)18.2507
2000's42 (12.07)29.6817
2010's199 (57.18)24.3611
2020's89 (25.57)2.80

Authors

AuthorsStudies
Chan, AWH; Coker, OO; Lau, HCH; Li, C; Lin, Y; Sung, JJY; Szeto, CH; Wei, H; Yang, J; Yu, J; Zhou, Y1
Gong, W; Gu, G; Hong, Z; Liu, J; Liu, P; Ren, H; Ren, J; Wang, G; Wu, X; Zhao, F; Zhao, Y; Zheng, T1
Chen, Z; Han, Y; Jiang, M; Liu, M; Pan, S; Tang, Z; Wang, S; Wang, Y; Xu, N; Yin, K; Zhang, G; Zhu, H1
Larypoor, M; Salimian, J; Shams, K1
Aprea, G; Borrelli, F; Brancaleone, V; Capasso, R; Cicia, D; D'Armiento, M; De Luca, M; Di Marzo, V; Di Tella, F; Fiorino, F; Iannotti, FA; Izzo, AA; Lionetti, R; Lucariello, G; Makriyannis, A; Malamas, M; Nanì, MF; Pagano, E; Piscitelli, F; Romano, B; Sbarro, B; Sparaco, R; Vanacore, G; Venneri, T1
Chen, IJ; Chen, YL; Cheng, KW; Cheng, TL; Chuang, CH; Ho, KW; Huang, BC; Huang, MY; Leu, YL; Lin, WW; Liu, HJ; Roffler, SR; Tseng, CH; Wang, JY1
Coker, OO; Kang, W; Li, C; Liu, C; Liu, D; Liu, Y; Sung, JJ; To, KF; Wang, Y; Wong, CC; Yu, J; Zhang, X; Zhou, Y1
Adileh, M; Baslan, T; Brown, AM; Fuks, Z; Hsu, KS; Hua, G; Klingler, S; Kolesnick, R; Martin, ML; Paty, PB; Zhang, Z1
Gan, Y; Gao, C; Huang, B; Liu, Y; Pan, D; Tang, Z1
Eferl, R; Gushchina, V; Kallay, E; Kupper, N; Manhardt, T; Mesteri, I; Moritsch, S; Müller, C; Piatek, K; Salzmann, M; Schepelmann, M; Vlasaty, A1
Chen, K; Gao, Z; Jia, H; Shi, Y; Wang, Z; Yuan, Y; Yue, T; Zeng, X1
Chang, J; Geng, Z; Hao, X; Liu, J; Tan, X; Wang, Z; Yan, S1
Kamakura, Y; Kawakami, S; Kojima, H; Kubota, A; Maeda, H; Miyashita, K; Murase, W; Mutoh, M; Ohta, T; Tanaka, T; Terasaki, M1
Chen, Q; Chu, Y; Dai, Y; Fang, Y; Lv, C; Wei, Z; Xia, Y; Yun, X; Zhang, Q; Zhu, Y1
Aladhami, A; Bader, JE; Chatzistamou, I; Cunningham, P; Enos, RT; Helms, H; Martinez-Muñiz, G; Noneman, MT; Patton, E; Shin, HK; Sumal, A; Unger, C; Velázquez, KT1
Choi, SI; Jang, JY; Kim, N; Lee, HN; Nam, RH; Song, CH1
Chen, Y; Diao, T; Li, D; Shang, G; Shi, L; Sun, L; Yin, X1
Chen, Q; Fu, J; Han, H; Lin, H; Lu, G; Ma, X; Qi, J; Wen, Z; Yang, M; Yang, X; Yang, Y; Yin, T1
Chen, W; Jin, X; Liu, B; Wu, P; Xiao, W; Yi, S1
Ajayi, BO; Ajeigbe, OF; Anyebe, DA; Farombi, EO; Maruf, OR; Opafunso, IT1
Archer, A; Birgersson, M; Hases, L; Indukuri, R; Williams, C1
Abdelghany, AH; Ahmad, J; Almaimani, R; Alsaegh, A; Aslam, A; Baghdadi, MA; El-Boshy, M; El-Readi, MZ; Elzubier, ME; Idris, S; Mahbub, AA; Refaat, B1
Chang, Y; Chen, H; Kang, J; Liang, X; Sun, M; Xiao, T; Zhang, J1
Hong, Y; Jia, ML; Li, YT; Liu, XM; Liu, ZQ; Yan, PK; Zhu, WT1
Ando, Y; Aoi, M; Fukui, T; Horitani, S; Matsumoto, Y; Naganuma, M; Okazaki, K; Tanaka, H; Tomiyama, T; Tsuneyama, K; Uragami, T1
Blecker, C; Fan, X; Guo, H; Qin, P; Ren, G; Richel, A; Teng, C; Yang, X; Zhang, L1
Huang, XH; Jiang, B; Ni, M; Wang, L; Xu, YY; Zhang, QQ; Zhang, R; Zhang, YQ; Zhao, Q1
Fan, RJ; Fang, MD; Ren, J; Tu, LL; Yao, WX; Zhang, YM; Zuo, BW1
Chen, Y; Kang, C; Li, J; Liu, Z; Zhang, Q; Zhu, W1
Arcos, M; Liu, Z; Martin, DR; Xue, X1
Du, M; Tian, Q; Wang, H; Xu, Z; Zhu, MJ1
Guo, X; Pu, W; Tang, S; Wang, X; Zhang, H; Zhang, T1
Chen, C; El-Nezami, H; Ismaiah, MJ; Leung, HKM; Lo, EKK; Zhang, F1
Fujisawa, Y; Kitamura, H; Nakagawa, N; Nishida, K; Xiang, H1
Kang, X; Kwong, TNY; Lam, TYT; Lin, Y; Liu, C; Ng, SK; Ni, Y; Sung, JJY; Wei, H; Wong, SH; Wu, WKK; Yu, J; Zhou, Y1
Bullard, BM; Cardaci, TD; Fan, D; Hofseth, LJ; Huss, AR; McDonald, SJ; Murphy, EA; VanderVeen, BN1
Fukui, T; Honzawa, Y; Horitani, S; Matsumoto, Y; Naganuma, M; Okazaki, K; Suzuki, R; Tahara, T; Tanimura, Y; Tomiyama, T1
Duan, J; Duan, W; Gao, Q; Li, J; Mao, T; Wang, M; Yan, J1
Chen, H; Fan, M; Fang, Y; Gou, H; Huang, Z; Li, X; Li, Y; Liu, D; Shang, H; Su, H; Wang, X; Wei, C; Wong, CC; Yu, J; Zeng, X; Zhang, X1
Baccigalupi, L; Balestrieri, ML; Borrelli, F; Cacciola, NA; Campanile, C; Campanile, G; Cuozzo, M; D'Occhio, MJ; D'Onofrio, N; Maiolino, P; Martano, M; Neglia, G; Ricca, E; Russo, R; Saggese, A; Salzano, A; Venneri, T; Vinale, F1
Abreu, AC; Aydos, RD; Fagundes, LS; Gonçalves, AF; Neves, MB; Ramalho, RT; Silva Junior, UND; Takita, LC1
Dzhalilova, D; Fokichev, N; Makarova, O; Zolotova, N1
Chen, X; Deng, Y; He, F; Huang, X; Tian, L; Wang, M; Yang, W; Yin, W; Zhou, H1
Djurhuus, D; Nielsen, B; Olsen, J; Pedersen, AE; Sadowska, Z; Tougaard, P; Yassin, M1
Chilton, BS; Helmer, RA; Kaur, G; Smith, LA1
El-Daly, SM; El-Khayat, Z; Hussein, J; Omara, EA; Youness, ER1
Li, Y; Liu, G; Liu, J; Ma, Y; Pan, Z; She, J; Wei, Q; Xia, H; Zhang, M; Zhang, RX1
Aranda-Vargas, PJ; Chávez-Servín, JL; de la Torre-Carbot, K; Ferríz-Martínez, RA; García-Gasca, T; González-Reyes, A; Kuri-García, A; Mejía, C; Moreno Celis, U; Saldaña Gutiérrez, C1
Costa, P; de la Fuente, VG; Fernández, J; García, MTF; Ledesma, E; Lombó, F; Martínez-Camblor, P; Millán, E; Monte, J; Villar, CJ1
Gao, Y; Hammad, A; Namani, A; Shi, HF; Tang, X; Zheng, ZH1
Ibuka, T; Kato, J; Kubota, M; Mizutani, T; Ohnishi, M; Sakai, H; Shimizu, M; Shirakami, Y; Tanaka, T1
Deng, W; Gao, S; Guan, XY; He, HH; Huang, J; Li, C; Shay, JW; Wang, G; Wang, S; Wei, H; Wong, CC; Wong, SH; Yu, J; Zeng, Y; Zhai, J; Zhang, Y; Zhao, L; Zhou, Y1
Chen, X; Han, W; Li, Y; Shi, L; Wan, J; Wang, H; Xie, B1
Gao, Z; Li, G; Liu, H; Zhang, L1
Bi, X; Guo, J; Mu, T; Yang, Z; Yue, J; Zhang, Q; Zhou, H1
Chia, YC; Fu, YS; Lin, SR; Lue, SI; Tsai, MJ; Tseng, FJ; Weng, CF; Woon, M; Zheng, JH1
Chac, D; DePaolo, RW; Kim, JH; Kordahi, MC1
Chen, N; Cheng, L; Dai, L; Deng, H; Dong, Z; Fang, C; Fu, J; Ji, Y; Li, J; Liu, Y; Shi, G; Su, X; Wang, H; Wang, W; Yang, Y; Yu, Y; Zhang, H; Zhang, S1
Eun, CS; Han, DS; Jo, SV; Lee, AR; Lee, JG; Park, CH1
Aggarwal, A; Baumgartner, M; Gasche, C; Gröschel, C; Heiden, D; Kallay, E; Karuthedom George, S; Lang, M; Manhardt, T; Marculescu, R; Mesteri, I; Prinz-Wohlgenannt, M; Schepelmann, M; Tennakoon, S; Trawnicek, L1
Angel, JM; Bissahoyo, AC; Demant, P; Elliott, RW; Lee, D; McMillan, L; Pardo-Manuel de Villena, F; Pearsall, RS; Threadgill, DW; Xie, Y; Yang, L1
Chen, D; Huang, Z; Liu, Y; Ma, H; Ouyang, G; Wang, J; Wu, T; Zhao, X1
Chartier, LC; Hebart, ML; Howarth, GS; Mashtoub, S; Whittaker, AL1
Hartung, NM; Kühl, AA; McDonald, FM; Ostermann, AI; Rohwer, N; Schebb, NH; Weylandt, KH; Zopf, D1
Benninghoff, AD; Hintze, KJ; Hunter, AH; Monsanto, SP; Pestka, JJ; Phatak, S; Rodriguez, DM; Ward, RE; Wettere, AJV1
Li, H; Li, Z; Shan, S; Shi, J; Yang, R; Zhang, C1
Huh, TG; Jeong, BJ; Jeong, JS; Kim, HY; Lee, JS; Park, KY; Song, JL1
Lin, L; Lin, Y; Qu, S; Wang, D; Zhao, H1
Qiao, PF; Yao, L; Zeng, ZL1
Bian, X; Chan, AWH; Chan, FKL; Coker, OO; El-Omar, E; Nakatsu, G; Sung, JJY; Wei, H; Wu, J; Yu, J; Zhao, L; Zhao, R; Zhou, Y1
Akbari, A; Asadollahi, P; Ghanavati, R; Javadi, A; Mohammadi, F; Rohani, M; Talebi, M1
Bonakdar, S; Emtyazjoo, M; Mostafavi, PG; Sahebi, Z1
Lin, R; Liu, C; Piao, M; Song, Y1
Kim, HJ; Lee, HW; Oh, JH; Park, BM; Roh, JI1
Alcalde, A; Arias, MA; Bird, PI; Camerer, E; Castro, M; Comas, L; Del Campo, R; Ferrandez, A; Galvez, EM; Garrido, M; Garzón, M; Gil-Gómez, G; Jaime-Sanchez, P; Lanuza, PM; Layunta, E; Martínez-Lostao, L; Metkar, S; Moreno, V; Muñoz, G; Pardo, J; Pelegrín, P; Peña, R; Ramirez-Labrada, A; Santiago, L; Sanz-Pamplona, R; Tapia, E; Uranga, JA; Uranga-Murillo, I1
Hu, Y; Ji, X; Li, Z; Liu, S; Lv, H; Ma, H; Wang, J; Wang, S; Wang, X; Wang, Y; Xu, Y; Zhang, B1
Ajani, JA; Anfossi, S; Bayraktar, R; Bhuvaneshwar, K; Burks, JK; Calin, GA; Chen, B; De Los Santos, MC; Dragomir, MP; Fabris, L; Ferracin, M; Fromm, B; Gagea, M; Girnita, L; Goel, A; Gusev, Y; Hanash, SM; Huo, L; Ivan, C; Ivkovic, TC; Katayama, H; Knutsen, E; Kopetz, S; Li, C; Li, Y; Ling, H; Liu, X; Matsuyama, T; Menter, D; Mimori, K; Multani, AS; Oki, E; Pardini, B; Parker-Thornburg, J; Reineke, LC; Sen, S; Shah, MY; Shen, P; Shimizu, M; Shimura, T; Slaby, O; Song, S; Syed, M; Taguchi, A; Tang, C; Uetake, H; Varani, G; Vasilescu, C1
Bai, R; Boardman, LA; Bode, AM; Chang, X; Chen, H; Dong, Z; Lim, DY; Ma, WY; Ryu, J; Wang, K; Wang, Q; Wang, T; Yao, K; Zhang, T1
Becker, C; Fichna, J; Jacenik, D; Kordek, R; Krajewska, WM; Sałaga, M; Schodel, L; Szymaszkiewicz, A; Zatorski, H; Zielińska, M1
Chan, H; Chan, MTV; Coker, OO; Gin, T; Hu, W; Huang, D; Kang, W; Li, Q; Liu, WX; Liu, XD; Ng, SSM; Wong, SH; Wu, JL; Wu, WKK; Yu, J; Zeng, JD; Zhang, L; Zhang, Y; Zhao, LY1
Chen, TH; Chen, YH; Chiu, CC; Chuang, HL; Huang, WC; Hung, SW; Lee, YP; Lin, TJ; Wang, YC1
Amini, N; Andreatos, N; Angelou, A; Antoniou, E; Buettner, S; Kamphues, C; Margonis, GA; Munir, M; Papalois, AE; Pikouli, A; Pikoulis, E; Pulvirenti, A; Sarantis, P; Theocharis, S; Theodoropoulos, G; Wang, J; Zografos, GC1
Eun Yu, J; Hee Nam, R; Hee Son, J; In Choi, S; Kim, DH; Kim, N; Lee, HN; Shin, E; Song, CH; Surh, YJ1
Bagni, C; Di Fusco, D; Di Grazia, A; Dinallo, V; Franzè, E; Laudisi, F; Marafini, I; Monteleone, G; Monteleone, I; Pedini, G; Rosina, E; Sica, G; Sileri, P; Stolfi, C1
Fernández, J; Ferreira-Lazarte, A; Gallego-Lobillo, P; Lombó, F; Moreno, FJ; Villamiel, M; Villar, CJ1
Liang, H; Lin, Z; Luo, R; Ye, Y; Zeng, L1
Qiao, PF; Wang, FJ; Wang, Y; Zhang, HG; Zhao, ZX1
Epifano, F; Fiorito, S; Genovese, S; Ibuka, T; Ideta, T; Kubota, M; Maruta, A; Miyazaki, T; Mizutani, T; Sakai, H; Shimizu, M; Shirakami, Y; Taddeo, VA; Tanaka, T1
Board, PG; Casarotto, MG; Dahlstrom, JE; Fernando, N; Hughes, MM; O'Neill, LAJ; Rooke, M; Takahashi, S; Tummala, P1
Chen, S; Chen, Y; Gao, J; Hou, S; Hu, J; Liang, J; Lin, J; Lu, Y; Wang, B; Yuan, X1
Basu, S; Dannenberg, AJ; Ito, N; Makino, T; Montrose, DC1
Alipour, M; Bandegi, AR; Pakdel, A; Sameni, HR; Semnani, V; Torabizadeh, N; Yosefi, S1
Hiramoto, K; Kawanishi, S; Ma, N; Murata, M; Ohnishi, S; Wang, G; Yoshikawa, N1
Lee, HJ; Lee, SM; Lim, YI; Park, ES; Park, KY; Yu, T1
He, JM; Hu, JN; Liang, X1
Aparna, JS; Athira, SR; Babu, A; Harikumar, KB; James, S; Kumar, SS; Lankadasari, MB; Mohammed, S; Namitha, NN; Paul, AM; Reshmi, G; Vijayan, Y1
Bailey, B; Dasgupta, S; DeBoever, C; Faustin, B; Grieves, J; Liu, H; Murphy, C; Wyrick, C1
Abba, MC; Blidner, AG; Cagnoni, AJ; Croci, DO; Cutine, AM; Gatto, SG; Giribaldi, ML; Mariño, KV; Morales, RM; Rabinovich, GA; Salatino, M1
Esa, NM; Ishak, NIM; Madzuki, IN; Mohamed, S; Mustapha, NM1
Ahn, JY; An, BC; Choi, O; Chung, MJ; Chung, Y; Kim, JF; Kim, TY; Kwon, SK; Park, HJ; Ryu, Y; Yoon, J; Yoon, YS1
Lei, J; Wei, Y; Zhang, H; Zhou, R1
Hopson, LM; Jogunoori, W; Lin, P; Mazumder, R; Miller, L; Mishra, L; Nguyen, BN; Obias, V; Rao, S; Singleton, SS; Wang, Z; White, J; Yang, X; Yao, M1
Ayala-Peña, S; Ballista-Hernández, J; Climent, C; Martínez-Ferrer, M; Rodríguez-Muñoz, A; Sánchez-Vázquez, MM; Torres, C; Torres-Ramos, CA; Vélez, R1
Amberg, N; Botti, G; Cardone, C; Ciardiello, F; Diamanti, MA; Dienes, HP; Eferl, R; Greten, FR; Holcmann, M; Kenner, L; Liguori, G; Linder, M; Martinelli, E; Pathria, P; Paul, MC; Prager, GW; Rose-John, S; Sibilia, M; Srivatsa, S; Timelthaler, G; Wrba, F1
Hayashi, SM; Kangawa, Y; Kataoka, A; Koyama, N; Ohsumi, T; Shibutani, M; Tanaka, T; Yoshida, T1
Berger, FG; Bridges, AE; Browning, DD; Hou, Y; Islam, BN; Kim, S; Kolhe, R; Rodriguez, PC; Sharman, SK; Singh, N; Sridhar, S; Trillo-Tinoco, J1
Barton, JK; Chandra, S; Gerner, EW; Nymeyer, AC; Rice, PF1
Crott, JW; Koh, GY; Mason, JB; Meydani, M; Pfalzer, AC; Tang, S; Thomas, MJ; Wu, X1
Chen, C; Kang, Q; Li, B; Peng, Y; Wu, Q; Xie, Y; Zhao, B1
Chan, FKL; Han, J; Kwong, TNY; Nakatsu, G; Sung, JJY; Tsoi, H; Wei, H; Wong, SH; Wu, WKK; Xiao, X; Xu, W; Yu, J; Zeng, B; Zhang, X; Zhao, L1
Bader, JE; Carson, JA; Carson, MS; Chatzistamou, I; Davis, JM; Enos, RT; Murphy, EA; Nagarkatti, M; Nagarkatti, PS; Robinson, CM; Velázquez, KT1
Chu, Y; Deng, Y; Gu, J; Huang, E; Jiang, X; Liu, G; Liu, J; Liu, R; Liu, X; Liu, Z; Lu, Z; Luo, F; Qian, J; Qian, Y; Wang, L; Wang, Z; Yang, J; Zhang, D; Zhang, H; Zhu, H1
Hou, G; Liu, S; Lou, X; Wang, Y1
Bi, W; Cao, L; He, C; Li, P; Liu, H; Peng, B; Shen, J; Xiao, P; Zhang, LH; Zhang, P1
Berggren, KL; Beswick, EJ; Gan, GN; Ray, AL; Restrepo Cruz, S1
Gao, L; Haraguchi, S; Ishida, F; Kim-Kaneyama, JR; Kudo, SE; Lei, XF; Li, S; Miyauchi, A; Miyazaki, A; Miyazaki, T; Nakahara, K; Ohnishi, K; Omoto, T; Orimo, A; Takeya, M; Tanaka, J; Umemoto, T; Yoshihara, K1
Lin, JA; Wu, CH; Yen, GC1
Chen, P; Hou, Z; Jia, H; Shen, B; Song, H; Sun, Y; Wang, W1
Cai, YK; Chen, J; Chen, WJ; Hao, Z; Lv, Y; Wang, HP; Wang, X; Ye, T; Zhao, JY1
Arning, E; Ashcraft, P; Cook, B; Genta, RM; Han, J; Holm, J; Jackson, D; Souza, RF; Sweetman, L; Theiss, AL; Turner, K; Venuprasad, K; Wang, X1
Bi, X; Chen, L; Guo, J; Jiang, B; Mu, T; Zhang, L; Zhang, Q; Zhong, C1
Campos-Vega, R; Cuellar-Nuñez, ML; Gallegos-Corona, MA; González de Mejía, E; Loarca-Piña, G; Luzardo-Ocampo, I1
An, HJ; Cheon, SY; Chung, KS; Lee, M; Roh, SS1
Cui, SX; Qu, XJ; Wang, F; Zhang, YS1
Mahmudah, N; Purnomosari, D; Widyarini, S1
Chevillard-Briet, M; Escaffit, F1
Gong, D; Hu, JL; Liu, LQ; Nie, SP; Shen, MY; Xie, MY; Yu, Q1
Ji, G; Sun, L; Tian, Y; Xu, Q; Ye, Y1
Chen, FY; Chen, YS; Ho, TY; Hsiang, CY; Lee, YC; Li, CC; Li, JM; Lo, HY1
Jia, W; Luo, Y; Niu, W; Wang, J; Wu, Z; Yang, M; Zhang, H; Zhang, X1
Melo, AFP; Mendonça, MCP; Rosa-Castro, RM1
Grill, JI; Herbst, A; Kolligs, FT; Marschall, MK; Neumann, J; Ofner, A; Wolf, E; Zierahn, H1
Ding, N; Gao, YH; Song, HL; Wang, M; Wen, H; Zhang, DM; Zhao, N1
Chen, Q; Deng, S; Dong, Y; Fan, H; Hu, J; Liu, X; Liu, Y; Nan, Z; Shou, Z; Tang, Q; Wang, H; Wu, H; Xu, M; Yang, J; Zhang, L; Zuo, D1
Dong, YW; Feng, Y; Guo, XY; Jiang, WL; Lu, LG; Song, YN; Xiao, JH1
Chang, YY; Huang, WJ; Jeng, YM; Jhuang, YL; Yang, CY; Yu, IS; Yu, LC1
Kim, JS; Kim, N; Lee, DH; Lee, HN; Lee, SM; Na, HY; Nam, RH; Park, JH; Shin, E; Sohn, SH; Son, HJ; Song, CH; Surh, YJ1
Barone, M; Di Leo, A; Giorgio, F; Girardi, B; Iannone, A; Ierardi, E; Losurdo, G; Pricci, M; Principi, M1
Chu, Y; Gu, J; Huang, E; Li, Y; Liang, Y; Liu, J; Liu, R; Lu, Z; Wang, L; Wang, Z; Yu, H; Zhang, D; Zhang, H1
Masuda, J; Seko, T; Umemura, C; Yamashita, M; Yamashita, Y; Yamauchi, K; Yokozawa, M1
Hu, C; Liu, C; Liu, S; Rong, J1
Campanholo, VMLP; Forones, NM; Ribeiro Paiotti, AP; Ribeiro, CCD; Ribeiro, DA; Silva, RM1
Arias, M; Castro, M; Pardo, J; Santiago, L1
Goto, K; Hiramoto, K; Kondo, K; Ooi, K; Sano, R1
Huang, G; Li, B; Lu, J; Ma, L; Su, J; Wang, Y; Xu, Y; Yin, L1
Arthur, JC; Rothemich, A1
Bader, JE; Carson, JA; Carson, M; Chatzistamou, I; Enos, RT; Kubinak, JL; Murphy, EA; Nagarkatti, M; Pena, MM; Sougiannis, AT; VanderVeen, BN; Velazquez, KT; Walla, M1
Braga, VNL; Cavalcanti, BC; Dornelas, CA; Jamacaru, FVF; Juanes, CC; Lemos, TLG; Peres Júnior, HS; Sousa, JR1
Chen, J; Du, RL; Gu, B; Li, SZ; Pan, WM; Song, Y; Xiang, Y; Zhang, HH; Zhang, XD; Zhao, H1
Fujimoto, S; Kida, Y; Kitamura, S; Miyamoto, H; Miyamoto, Y; Muguruma, N; Nakagawa, T; Nakamura, F; Okada, Y; Okamoto, K; Sato, Y; Takayama, T; Tanaka, K1
Choi, SI; Kang, SR; Kim, N; Lee, DH; Lee, HN; Lee, SM; Nam, RH; Shin, E; Song, CH; Surh, YJ1
Awadallah, JR; El-Bana, MA; El-Daly, SM; Gamal-Eldeen, AM; Latif, YA; Medhat, D; Morsy, SM; Omara, EA1
Hasegawa, H; Ishida, T; Kitagawa, Y; Kondo, T; Matsui, S; Okabayashi, K; Sato, T; Seishima, R; Shigeta, K; Shimoda, M; Sugimoto, S; Suzuki, Y; Tsuruta, M1
Alexander, JS; Bernas, M; Daley, SK; Kiela, P; Tanoue, N; Thorn, J; Washington, J; Witte, MH1
Fujita, M; Fukai, F; Ishibashi, K; Ito-Fujita, Y; Iyoda, T; Kodama, H; Okada, Y; Osawa, T; Sasada, M; Suzuki, H1
Chen, M; Hou, Y; Li, P; Ma, X; Qiao, X; Sun, M; Wen, X; Yang, J; Zhang, L1
Cherubini, F; Colantoni, A; De Simone, V; Di Fusco, D; Di Grazia, A; Dinallo, V; Fearon, ER; Franzè, E; Laudisi, F; Monteleone, G; Monteleone, I; Ortenzi, A; Stolfi, C1
Akitake-Kawano, R; Chiba, T; Kanda, K; Kawada, K; Kawada, M; Kimura, Y; Nakanishi, Y; Nakatsuji, M; Sakai, Y; Seno, H; Yoshioka, T1
Ji, G; Li, N; Tian, Y; Wang, K; Wang, Z1
Rahman, MM; Seo, YR1
Imai, T; Ishigamori, R; Ito, K; Mutoh, M; Ohta, T; Takahashi, M1
Gao, Y; Li, X; Liu, X; Lu, X; Wang, G; Wu, J; Wu, Q; Yang, M; Yang, Y; Zhang, Y; Zhao, Q1
Cooks, T; Forshew, T; Gorgoulis, VG; Harpaz, N; Harris, CC; Itzkowitz, S; Lozano, G; Oren, M; Pateras, IS; Pikarsky, E; Rosenfeld, N; Rotter, V; Rozenfeld, N; Schetter, AJ; Solomon, H; Tarcic, O; Wilder, S1
Hu, Y; Le Leu, RK; McIntosh, GH; Nyskohus, LS; Woodman, RJ; Young, GP1
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Reviews

3 review(s) available for azoxymethane and Colorectal Cancer

ArticleYear
Murine models of colorectal cancer: the azoxymethane (AOM)/dextran sulfate sodium (DSS) model of colitis-associated cancer.
    PeerJ, 2023, Volume: 11

    Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Mice

2023
Impact of physical activity on intestinal cancer development in mice.
    The Journal of nutrition, 2005, Volume: 135, Issue:12 Suppl

    Topics: 1,2-Dimethylhydrazine; Animals; Azoxymethane; Body Mass Index; Body Weight; Carcinogens; Colorectal Neoplasms; Diet; Male; Mice; Motor Activity; Rats; Rats, Inbred F344; Rats, Sprague-Dawley

2005
[Experimental models for hepatic metastases from colorectal tumors].
    Annales de chirurgie, 1991, Volume: 45, Issue:3

    Topics: Animals; Azoxymethane; Colectomy; Colorectal Neoplasms; Cyclosporins; Disease Models, Animal; Fluorouracil; Liver Neoplasms; Rats; Tumor Cells, Cultured

1991

Other Studies

345 other study(ies) available for azoxymethane and Colorectal Cancer

ArticleYear
High-Fat Diet Promotes Colorectal Tumorigenesis Through Modulating Gut Microbiota and Metabolites.
    Gastroenterology, 2022, Volume: 162, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Azoxymethane; Bacteria; Bacterial Translocation; Cell Proliferation; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; Diet, High-Fat; Disease Models, Animal; Dysbiosis; Fecal Microbiota Transplantation; Feces; Gastrointestinal Microbiome; Genes, APC; Germ-Free Life; Humans; Lysophospholipids; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Permeability; Tumor Cells, Cultured

2022
STING-mediated Syk Signaling Attenuates Tumorigenesis of Colitis‑associated Colorectal Cancer Through Enhancing Intestinal Epithelium Pyroptosis.
    Inflammatory bowel diseases, 2022, 03-30, Volume: 28, Issue:4

    Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Pyroptosis; Syk Kinase

2022
Stimulation of hypothalamic oxytocin neurons suppresses colorectal cancer progression in mice.
    eLife, 2021, 09-16, Volume: 10

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Hypothalamus; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Oxytocin; Pentacyclic Triterpenes

2021
The immunomodulatory effects of Candida albicans isolated from the normal gastrointestinal microbiome of the elderly on colorectal cancer.
    Medical oncology (Northwood, London, England), 2021, Oct-12, Volume: 38, Issue:12

    Topics: Animals; Azoxymethane; Candida albicans; Colorectal Neoplasms; Cytokines; Gastrointestinal Microbiome; Immunomodulating Agents; Lactobacillus plantarum; Male; Probiotics; Rats; Rats, Inbred F344

2021
N-Acylethanolamine acid amidase (NAAA) is dysregulated in colorectal cancer patients and its inhibition reduces experimental cancer growth.
    British journal of pharmacology, 2022, Volume: 179, Issue:8

    Topics: Amidohydrolases; Azoxymethane; Colorectal Neoplasms; Ethanolamines; Humans

2022
Inhibition of gut microbial β-glucuronidase effectively prevents carcinogen-induced microbial dysbiosis and intestinal tumorigenesis.
    Pharmacological research, 2022, Volume: 177

    Topics: Animals; Azoxymethane; Bacteria; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Colorectal Neoplasms; Dysbiosis; Gastrointestinal Microbiome; Glucuronidase; Mice

2022
Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis.
    Gut, 2022, Volume: 71, Issue:11

    Topics: Animals; Azoxymethane; Bile Acids and Salts; Carcinogenesis; Cell Proliferation; Cholesterol; Colorectal Neoplasms; Dysbiosis; Fluorouracil; Mice; Occludin; Oxaliplatin; RNA, Messenger; Squalene Monooxygenase; Terbinafine

2022
Disruption of the crypt niche promotes outgrowth of mutated colorectal tumor stem cells.
    JCI insight, 2022, 03-08, Volume: 7, Issue:5

    Topics: Adenoma; Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Humans; Mice; Neoplastic Stem Cells

2022
Phycocyanin Ameliorates Colitis-Associated Colorectal Cancer by Regulating the Gut Microbiota and the IL-17 Signaling Pathway.
    Marine drugs, 2022, Apr-09, Volume: 20, Issue:4

    Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Interleukin-17; Mice; Mice, Inbred C57BL; Phycocyanin; Signal Transduction

2022
AOM/DSS Induced Colitis-Associated Colorectal Cancer in 14-Month-Old Female Balb/C and C57/Bl6 Mice-A Pilot Study.
    International journal of molecular sciences, 2022, May-09, Volume: 23, Issue:9

    Topics: Animals; Azoxymethane; Carcinogenesis; Carcinoma; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pilot Projects

2022
    Food & function, 2022, Jul-04, Volume: 13, Issue:13

    Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Kefir; Lactobacillus; Mice; RNA, Ribosomal, 16S; Saccharomyces cerevisiae; Tibet

2022
Berberine regulates short-chain fatty acid metabolism and alleviates the colitis-associated colorectal tumorigenesis through remodeling intestinal flora.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Jul-20, Volume: 102

    Topics: Animals; Azoxymethane; Berberine; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Fatty Acids, Volatile; Gastrointestinal Microbiome; Interleukin-6; Lipopolysaccharides; Mice; Mice, Inbred C57BL; NF-kappa B; Occludin; Tandem Mass Spectrometry; Toll-Like Receptor 4

2022
A Biscuit Containing Fucoxanthin Prevents Colorectal Carcinogenesis in Mice.
    Nutrition and cancer, 2022, Volume: 74, Issue:10

    Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Mice; Xanthophylls

2022
Madecassic acid alleviates colitis-associated colorectal cancer by blocking the recruitment of myeloid-derived suppressor cells via the inhibition of IL-17 expression in γδT17 cells.
    Biochemical pharmacology, 2022, Volume: 202

    Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Interleukin-17; Mice; Mice, Inbred C57BL; Myeloid-Derived Suppressor Cells; Receptors, Antigen, T-Cell, gamma-delta; Signal Transduction; Th17 Cells; Triterpenes; Tumor Microenvironment

2022
Ojeok-san ameliorates visceral and somatic nociception in a mouse model of colitis induced colorectal cancer.
    PloS one, 2022, Volume: 17, Issue:6

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Inbred C57BL; Nociception; Plant Extracts

2022
Changes in Gut Microbiome upon Orchiectomy and Testosterone Administration in AOM/DSS-Induced Colon Cancer Mouse Model.
    Cancer research and treatment, 2023, Volume: 55, Issue:1

    Topics: Animals; Azoxymethane; Colonic Neoplasms; Colorectal Neoplasms; Disease Models, Animal; Female; Gastrointestinal Microbiome; Male; Mice; Orchiectomy; Phylogeny; RNA, Ribosomal, 16S; Testosterone

2023
Aspirin Inhibits Carcinogenesis of Intestinal Mucosal Cells in UC Mice Through Inhibiting IL-6/JAK/STAT3 Signaling Pathway and Modulating Apoptosis and Proliferation.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2022, Volume: 33, Issue:9

    Topics: Animals; Apoptosis; Aspirin; Azoxymethane; Carcinogenesis; Cell Proliferation; Colitis, Ulcerative; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Hyperplasia; Inflammation; Interleukin-10; Interleukin-6; Janus Kinases; Mice; Proliferating Cell Nuclear Antigen; Signal Transduction; STAT3 Transcription Factor

2022
Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer.
    International immunopharmacology, 2022, Volume: 111

    Topics: Animals; Azoxymethane; Bacteroidetes; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Firmicutes; Humans; Inflammation; Mice; Mice, Inbred C57BL; Naphthoquinones; Tumor Microenvironment

2022
Portulaca oleracea extract reduces gut microbiota imbalance and inhibits colorectal cancer progression via inactivation of the Wnt/β-catenin signaling pathway.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 105

    Topics: Animals; Azoxymethane; beta Catenin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Gastrointestinal Microbiome; Gene Expression Regulation, Neoplastic; Mice; Portulaca; Wnt Signaling Pathway

2022
6- shogaol suppresses AOM/DSS-mediated colorectal adenoma through its antioxidant and anti-inflammatory effects in mice.
    Journal of food biochemistry, 2022, Volume: 46, Issue:12

    Topics: Adenoma; Animals; Anti-Inflammatory Agents; Antioxidants; Azoxymethane; Colonic Neoplasms; Colorectal Neoplasms; Disease Models, Animal; Inflammation; Male; Mice

2022
Colitis Induces Sex-Specific Intestinal Transcriptomic Responses in Mice.
    International journal of molecular sciences, 2022, Sep-08, Volume: 23, Issue:18

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Humans; Inflammation; Inflammatory Bowel Diseases; Male; Mice; Mice, Inbred C57BL; Receptors, Glucocorticoid; RNA; Transcriptome

2022
Enhanced anti-cancer effects of oestrogen and progesterone co-therapy against colorectal cancer in males.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Androgen Antagonists; Androgens; Animals; Azoxymethane; Caspase 3; Colorectal Neoplasms; Cytochromes; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Gonadal Steroid Hormones; Humans; Male; Mice; Progesterone; Prostatic Neoplasms; Receptors, Progesterone; RNA, Messenger; Survivin; Testosterone

2022
Butyrate ameliorates colorectal cancer through regulating intestinal microecological disorders.
    Anti-cancer drugs, 2023, 02-01, Volume: 34, Issue:2

    Topics: Animals; Azoxymethane; Butyrates; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Mice; Mice, Inbred C57BL

2023
Rapamycin Liposomes Combined with 5-Fluorouracil Inhibits Angiogenesis and Tumor Growth of APC
    International journal of nanomedicine, 2022, Volume: 17

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Fluorouracil; Lipopolysaccharides; Liposomes; Mice; Mice, Inbred C57BL; Sirolimus

2022
Establishment of a Novel Colitis-Associated Cancer Mouse Model Showing Flat Invasive Neoplasia.
    Digestive diseases and sciences, 2023, Volume: 68, Issue:5

    Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Dextrans; Disease Models, Animal; Humans; Inflammation; Mice; Reproducibility of Results

2023
Supplementation of quinoa peptides alleviates colorectal cancer and restores gut microbiota in AOM/DSS-treated mice.
    Food chemistry, 2023, May-15, Volume: 408

    Topics: Animals; Azoxymethane; Chenopodium quinoa; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Mice; Mice, Inbred C57BL; Peptides; Probiotics

2023
Ginsenoside Rb1 Suppresses AOM/DSS-induced Colon Carcinogenesis.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:9

    Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colorectal Neoplasms; Disease Models, Animal; Ginsenosides; Inflammation; Mice; Mice, Inbred C57BL; Tumor Microenvironment

2023
Boris knockout eliminates AOM/DSS-induced in situ colorectal cancer by suppressing DNA damage repair and inflammation.
    Cancer science, 2023, Volume: 114, Issue:5

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; DNA Damage; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout

2023
AC1Q3QWB inhibits colorectal cancer progression by modulating the immune response and balancing the structure of the intestinal microbiota.
    International immunopharmacology, 2023, Volume: 116

    Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Dimethyl Sulfoxide; Disease Models, Animal; Gastrointestinal Microbiome; Immunity; Mice; Mice, Inbred C57BL; RNA, Ribosomal, 16S

2023
Myeloid FTH1 Deficiency Protects Mice From Colitis and Colitis-associated Colorectal Cancer via Reducing DMT1-Imported Iron and STAT3 Activation.
    Inflammatory bowel diseases, 2023, 08-01, Volume: 29, Issue:8

    Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Iron; Mice; Mice, Inbred C57BL; STAT3 Transcription Factor

2023
Metabolomic profiling for the preventive effects of dietary grape pomace against colorectal cancer.
    The Journal of nutritional biochemistry, 2023, Volume: 116

    Topics: Animals; Azoxymethane; Colorectal Neoplasms; Diet; Dietary Supplements; Disease Models, Animal; Metabolomics; Mice; Vitis

2023
Inhibitory effects of
    Frontiers in immunology, 2023, Volume: 14

    Topics: Animals; Azoxymethane; Clostridium butyricum; Colitis; Colorectal Neoplasms; Cytokines; Mice; Mice, Inbred C57BL

2023
Zearalenone attenuates colitis associated colorectal tumorigenesis through Ras/Raf/ERK pathway suppression and SCFA-producing bacteria promotion.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 164

    Topics: Animals; Azoxymethane; Bacteria; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Humans; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Zearalenone

2023
Inhibitory Effect of Zinc on Colorectal Cancer by Granzyme B Transcriptional Regulation in Cytotoxic T Cells.
    International journal of molecular sciences, 2023, May-29, Volume: 24, Issue:11

    Topics: Animals; Azoxymethane; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Granzymes; Mice; T-Lymphocytes, Cytotoxic; Zinc

2023
Altered gut microbiota of obesity subjects promotes colorectal carcinogenesis in mice.
    EBioMedicine, 2023, Volume: 93

    Topics: Animals; Azoxymethane; Carcinogenesis; Colonic Neoplasms; Colorectal Neoplasms; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Mice; Mice, Inbred C57BL; Obesity

2023
Panaxynol alleviates colorectal cancer in a murine model via suppressing macrophages and inflammation.
    American journal of physiology. Gastrointestinal and liver physiology, 2023, 10-01, Volume: 325, Issue:4

    Topics: Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mucins

2023
A Short-Term Model of Colitis-Associated Colorectal Cancer That Suggests Initial Tumor Development and the Characteristics of Cancer Stem Cells.
    International journal of molecular sciences, 2023, Jul-20, Volume: 24, Issue:14

    Topics: Animals; Azoxymethane; beta Catenin; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Humans; Ki-67 Antigen; Mice; Mice, Inbred C57BL; Neoplastic Stem Cells

2023
ENPP2 inhibitor improves proliferation in AOM/DSS-induced colorectal cancer mice via remodeling the gut barrier function and gut microbiota composition.
    Pharmacological research, 2023, Volume: 195

    Topics: Animals; Azoxymethane; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Mice; Mice, Inbred C57BL; Phosphoric Diester Hydrolases

2023
Traditional Medicine Pien Tze Huang Suppresses Colorectal Tumorigenesis Through Restoring Gut Microbiota and Metabolites.
    Gastroenterology, 2023, Volume: 165, Issue:6

    Topics: Animals; Apoptosis; Azoxymethane; Carcinogenesis; Colorectal Neoplasms; Dextran Sulfate; Gastrointestinal Microbiome; Medicine, Traditional; Mice; Phosphatidylinositol 3-Kinases; Signal Transduction

2023
Chemopreventive effect of a milk whey by-product derived from Buffalo (Bubalus bubalis) in protecting from colorectal carcinogenesis.
    Cell communication and signaling : CCS, 2023, 09-20, Volume: 21, Issue:1

    Topics: Animals; Azoxymethane; Buffaloes; Butyric Acid; Carcinogenesis; Colorectal Neoplasms; Humans; Mice; Milk; Whey

2023
The effect of aerobic and resistance exercise on the progression of colorectal cancer in an animal model.
    Acta cirurgica brasileira, 2023, Volume: 38

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Resistance Training

2023
Chemopreventive Effects of Polysaccharides and Flavonoids from Okra Flowers in Azomethane/Dextran Sulfate Sodium-Induced Murine Colitis-Associated Cancer.
    Nutrients, 2023, Nov-17, Volume: 15, Issue:22

    Topics: Abelmoschus; Animals; Anticarcinogenic Agents; Azoxymethane; beta Catenin; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Flavonoids; Hominidae; Humans; Interleukin-6; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt

2023
Upregulation of PD-1 follows tumour development in the AOM/DSS model of inflammation-induced colorectal cancer in mice.
    Immunology, 2019, Volume: 158, Issue:1

    Topics: Animals; Azoxymethane; B7-H1 Antigen; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Intestinal Mucosa; Lymphocyte Activation; Mice, Inbred C57BL; Phenotype; Programmed Cell Death 1 Ligand 2 Protein; Programmed Cell Death 1 Receptor; Signal Transduction; T-Lymphocytes; Up-Regulation

2019
Helicase-like transcription factor (Hltf) gene-deletion promotes oxidative phosphorylation (OXPHOS) in colorectal tumors of AOM/DSS-treated mice.
    PloS one, 2019, Volume: 14, Issue:8

    Topics: Adenocarcinoma; Animals; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; DNA-Binding Proteins; Gene Deletion; Gene Expression Regulation, Neoplastic; Mice, Inbred C57BL; Mitochondria; Oxidative Phosphorylation; Survival Analysis; Transcription Factors

2019
Differential expression of miRNAs regulating NF-κB and STAT3 crosstalk during colitis-associated tumorigenesis.
    Molecular and cellular probes, 2019, Volume: 47

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; MicroRNAs; NF-kappa B; Signal Transduction; STAT3 Transcription Factor

2019
Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch.
    Journal of visualized experiments : JoVE, 2019, 08-24, Issue:150

    Topics: Adenocarcinoma; Animals; Appendectomy; Azoxymethane; Carcinogens; Cecum; Chronic Disease; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Male; Mice, Inbred C57BL

2019
Effect on nutritional markers of a model of aberrant crypt foci induced by azoxymethane and sodium dextran sulfate in Sprague Dawley rats.
    Nutricion hospitalaria, 2019, Oct-17, Volume: 36, Issue:5

    Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Male; Nutritional Physiological Phenomena; Rats; Rats, Sprague-Dawley

2019
Traditional Processed Meat Products Re-designed Towards Inulin-rich Functional Foods Reduce Polyps in Two Colorectal Cancer Animal Models.
    Scientific reports, 2019, 10-15, Volume: 9, Issue:1

    Topics: Animals; Azoxymethane; Colon; Colorectal Neoplasms; Dextran Sulfate; Dietary Fiber; Fatty Acids, Volatile; Functional Food; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Intestinal Polyps; Inulin; Male; Meat Products; Metagenomics; Neoplasms, Experimental; Prebiotics; Rats; Swine

2019
Identification of novel Nrf2 target genes as prognostic biomarkers in colitis-associated colorectal cancer in Nrf2-deficient mice.
    Life sciences, 2019, Dec-01, Volume: 238

    Topics: Animals; Azoxymethane; Biomarkers; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Signal Transduction

2019
Suppressive effects of the sodium‑glucose cotransporter 2 inhibitor tofogliflozin on colorectal tumorigenesis in diabetic and obese mice.
    Oncology reports, 2019, Volume: 42, Issue:6

    Topics: Animals; Azoxymethane; Benzhydryl Compounds; Blood Glucose; Carcinogenesis; Cell Proliferation; Colorectal Neoplasms; Diabetes Mellitus, Type 2; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Hypoglycemic Agents; Mice; Mice, Inbred NOD; Mice, Obese; Obesity; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Tumor Necrosis Factor-alpha

2019
MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 02-01, Volume: 26, Issue:3

    Topics: Aneuploidy; Animals; Apoptosis; Azoxymethane; Carcinogenesis; Carcinogens; Cell Proliferation; Chromosomal Instability; Colorectal Neoplasms; Humans; Mice; Mice, Knockout; Microtubule-Associated Proteins; Mitosis; Prognosis; Survival Rate; Tumor Cells, Cultured

2020
Orally Deliverable Nanotherapeutics for the Synergistic Treatment of Colitis-Associated Colorectal Cancer.
    Theranostics, 2019, Volume: 9, Issue:24

    Topics: Administration, Oral; Animals; Apoptosis; Azoxymethane; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colitis; Colorectal Neoplasms; Curcumin; Cytokines; Dextran Sulfate; Disease Models, Animal; Disease Progression; Drug Synergism; Female; Inflammation; Inflammation Mediators; Intestines; Irinotecan; Macrophages; Mice; Mice, Inbred C57BL; Nanoparticles; RAW 264.7 Cells

2019
Xanthohumol protects against Azoxymethane-induced colorectal cancer in Sprague-Dawley rats.
    Environmental toxicology, 2020, Volume: 35, Issue:2

    Topics: Aberrant Crypt Foci; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Azoxymethane; Cell Proliferation; Colorectal Neoplasms; Flavonoids; Humans; Male; Propiophenones; Rats; Rats, Sprague-Dawley

2020
Upregulation of DKK3 by miR-483-3p plays an important role in the chemoprevention of colorectal cancer mediated by black raspberry anthocyanins.
    Molecular carcinogenesis, 2020, Volume: 59, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Animals; Anthocyanins; Azoxymethane; Cell Line, Tumor; Cell Proliferation; Chemoprevention; Colorectal Neoplasms; Dextran Sulfate; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Mice, Inbred C57BL; MicroRNAs; Rubus; Survival Analysis; Up-Regulation

2020
Clerodane Diterpene Ameliorates Inflammatory Bowel Disease and Potentiates Cell Apoptosis of Colorectal Cancer.
    Biomolecules, 2019, 11-21, Volume: 9, Issue:12

    Topics: Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Caco-2 Cells; Cell Cycle; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dextran Sulfate; Diterpenes, Clerodane; Fluorouracil; HT29 Cells; Humans; Inflammation; Inflammatory Bowel Diseases; Intestines; Male; Mice, Inbred C57BL

2019
Toll-like Receptor-6 Signaling Prevents Inflammation and Impacts Composition of the Microbiota During Inflammation-Induced Colorectal Cancer.
    Cancer prevention research (Philadelphia, Pa.), 2020, Volume: 13, Issue:1

    Topics: Animals; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Female; Gastrointestinal Microbiome; Humans; Immunity, Innate; Interleukin-10; Intestinal Mucosa; Lactobacillus; Mice; Mice, Knockout; Neoplasms, Experimental; Probiotics; Proteobacteria; Recombinant Proteins; Signal Transduction; Toll-Like Receptor 6

2020
Temporal DNA methylation pattern and targeted therapy in colitis-associated cancer.
    Carcinogenesis, 2020, 04-22, Volume: 41, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Azoxymethane; bcl-Associated Death Protein; Carcinogenesis; Cell Line, Tumor; Colitis; Colon; Colonoscopy; Colorectal Neoplasms; Decitabine; Disease Models, Animal; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Male; Mice; Molecular Targeted Therapy; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Up-Regulation

2020
The impact of gut microbiota manipulation with antibiotics on colon tumorigenesis in a murine model.
    PloS one, 2019, Volume: 14, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Microbiome; High-Throughput Nucleotide Sequencing; Inflammation; Mice; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Tumor Burden

2019
Switching to a Healthy Diet Prevents the Detrimental Effects of Western Diet in a Colitis-Associated Colorectal Cancer Model.
    Nutrients, 2019, Dec-23, Volume: 12, Issue:1

    Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Diet, Healthy; Diet, Western; Disease Models, Animal; Female; Gastrointestinal Microbiome; Liver; Mice; Mice, Inbred BALB C; Vitamin D

2019
A New Polygenic Model for Nonfamilial Colorectal Cancer Inheritance Based on the Genetic Architecture of the Azoxymethane-Induced Mouse Model.
    Genetics, 2020, Volume: 214, Issue:3

    Topics: Alleles; Animals; Azoxymethane; Colorectal Neoplasms; Disease Models, Animal; Drug Resistance, Neoplasm; Genetic Heterogeneity; Genetic Predisposition to Disease; Genome-Wide Association Study; Heredity; Humans; Mice; Mice, Inbred Strains; Models, Genetic; Multifactorial Inheritance

2020
Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation.
    Cell reports, 2020, 01-21, Volume: 30, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Adenomatous Polyposis Coli; Animals; Azoxymethane; Carcinogenesis; Cell Adhesion Molecules; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Focal Adhesion Protein-Tyrosine Kinases; Humans; Inflammation; Integrins; Interleukin-6; Intestines; Mice, Inbred C57BL; Myofibroblasts; Precancerous Conditions; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Stromal Cells; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins

2020
Affective state determination in a mouse model of colitis-associated colorectal cancer.
    PloS one, 2020, Volume: 15, Issue:1

    Topics: Animals; Azoxymethane; Behavior; Buprenorphine; Colitis; Colonoscopy; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Mice; Mice, Inbred C57BL; Pain Measurement; Retrospective Studies; Risk Assessment

2020
Effects of chronic low-dose aspirin treatment on tumor prevention in three mouse models of intestinal tumorigenesis.
    Cancer medicine, 2020, Volume: 9, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Azoxymethane; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Dose-Response Relationship, Drug; Female; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Tumor Cells, Cultured

2020
Consumption of the Total Western Diet Promotes Colitis and Inflammation-Associated Colorectal Cancer in Mice.
    Nutrients, 2020, Feb-20, Volume: 12, Issue:2

    Topics: Adaptive Immunity; Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Diet, Western; Disease Models, Animal; Immunity, Innate; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; RNA, Messenger

2020
Inhibitory Effects of Bound Polyphenol from Foxtail Millet Bran on Colitis-Associated Carcinogenesis by the Restoration of Gut Microbiota in a Mice Model.
    Journal of agricultural and food chemistry, 2020, Mar-18, Volume: 68, Issue:11

    Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colorectal Neoplasms; Dextran Sulfate; Ecosystem; Gastrointestinal Microbiome; Mice; Mice, Nude; Polyphenols; RNA, Ribosomal, 16S; Setaria Plant

2020
Dietary Mixed Cereal Grains Ameliorate the Azoxymethane and Dextran Sodium Sulfate-Induced Colonic Carcinogenesis in C57BL/6J Mice.
    Journal of medicinal food, 2020, Volume: 23, Issue:4

    Topics: Animals; Azoxymethane; Carcinogenesis; Caspase 3; Colon; Colonic Neoplasms; Colorectal Neoplasms; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Dietary Carbohydrates; Disease Models, Animal; Edible Grain; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; RNA, Messenger; Tumor Necrosis Factors; Tumor Suppressor Protein p53

2020
miR-370-3p Alleviates Ulcerative Colitis-Related Colorectal Cancer in Mice Through Inhibiting the Inflammatory Response and Epithelial-Mesenchymal Transition.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Animals; Azoxymethane; Cell Proliferation; Cells, Cultured; Colitis, Ulcerative; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Epithelial-Mesenchymal Transition; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; MicroRNAs

2020
Catalpol‑mediated microRNA‑34a suppresses autophagy and malignancy by regulating SIRT1 in colorectal cancer.
    Oncology reports, 2020, Volume: 43, Issue:4

    Topics: Aged; Animals; Apoptosis; Autophagy; Azoxymethane; Carcinogens; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Colorectal Neoplasms; Disease Models, Animal; Drugs, Chinese Herbal; Female; Gene Expression Regulation, Neoplastic; Humans; Iridoid Glucosides; Male; MicroRNAs; Middle Aged; Rats; Rats, Wistar; Rehmannia; Sirtuin 1; Up-Regulation

2020
Aspirin Reduces Colorectal Tumor Development in Mice and Gut Microbes Reduce its Bioavailability and Chemopreventive Effects.
    Gastroenterology, 2020, Volume: 159, Issue:3

    Topics: Adenomatous Polyposis Coli Protein; Animals; Anti-Bacterial Agents; Anticarcinogenic Agents; Aspirin; Azoxymethane; Bacillaceae; Bacteroides fragilis; Bacteroidetes; Biological Availability; Carcinogenesis; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; DNA, Bacterial; Dose-Response Relationship, Drug; Feces; Gastrointestinal Microbiome; Germ-Free Life; Humans; Intestinal Mucosa; Male; Mice; Mice, Transgenic; RNA, Ribosomal, 16S

2020
Lactobacillus species inhibitory effect on colorectal cancer progression through modulating the Wnt/β-catenin signaling pathway.
    Molecular and cellular biochemistry, 2020, Volume: 470, Issue:1-2

    Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Female; Flow Cytometry; Gastrointestinal Microbiome; HT29 Cells; Humans; Inflammation; Lactobacillus; Mice; Mice, Inbred BALB C; Probiotics; Real-Time Polymerase Chain Reaction; Wnt Signaling Pathway

2020
Promising Chemoprevention of Colonic Aberrant Crypt Foci by
    Anti-cancer agents in medicinal chemistry, 2020, Volume: 20, Issue:17

    Topics: Aberrant Crypt Foci; Animals; Antineoplastic Agents; Antioxidants; Azoxymethane; Biphenyl Compounds; Brachyura; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Injections, Intradermal; Male; Molecular Structure; Muscles; Neoplasms, Experimental; Picrates; Rats; Rats, Wistar; Structure-Activity Relationship; Tumor Cells, Cultured

2020
Quercetin Suppresses AOM/DSS-Induced Colon Carcinogenesis through Its Anti-Inflammation Effects in Mice.
    Journal of immunology research, 2020, Volume: 2020

    Topics: Animals; Antineoplastic Agents; Azoxymethane; Biomarkers, Tumor; Carcinogenesis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Gentian Violet; Humans; Hydroxybutyrates; Mice; Mice, Inbred C57BL; Oxidative Stress; Quercetin; Tumor Burden

2020
Effect of PIERCE1 on colorectal cancer.
    Experimental animals, 2020, Nov-12, Volume: 69, Issue:4

    Topics: Animals; Azoxymethane; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gene Expression; Humans; Male; Mice, Transgenic; Tumor Suppressor Protein p53

2020
Extracellular Granzyme A Promotes Colorectal Cancer Development by Enhancing Gut Inflammation.
    Cell reports, 2020, 07-07, Volume: 32, Issue:1

    Topics: Acute Disease; Animals; Azoxymethane; Carcinogenesis; Chronic Disease; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Disease Progression; Extracellular Space; Granzymes; Humans; Inflammasomes; Inflammation; Inflammation Mediators; Interleukin-6; Mice, Knockout; NF-kappa B; RNA, Messenger

2020
Dietary Supplementation of Foxtail Millet Ameliorates Colitis-Associated Colorectal Cancer in Mice via Activation of Gut Receptors and Suppression of the STAT3 Pathway.
    Nutrients, 2020, Aug-07, Volume: 12, Issue:8

    Topics: Animals; Azoxymethane; Basic Helix-Loop-Helix Transcription Factors; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Diet; Dietary Supplements; Disease Models, Animal; Disease Progression; Gastrointestinal Microbiome; Interleukin-17; Interleukin-6; Mice; Mice, Inbred BALB C; Oryza; Phosphorylation; Receptors, Aryl Hydrocarbon; Receptors, G-Protein-Coupled; Setaria Plant; Signal Transduction; STAT3 Transcription Factor

2020
The Long Noncoding RNA CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling.
    Gastroenterology, 2020, Volume: 159, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase B; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Chromosomal Instability; Colon; Colorectal Neoplasms; Cytogenetic Analysis; Dextrans; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Intestinal Mucosa; Male; Mice; Mice, Transgenic; Neoplasms, Experimental; Organoids; Primary Cell Culture; Proto-Oncogene Proteins c-myc; RNA-Binding Proteins; RNA, Long Noncoding; Signal Transduction

2020
ARC Is a Critical Protector against Inflammatory Bowel Disease (IBD) and IBD-Associated Colorectal Tumorigenesis.
    Cancer research, 2020, 10-01, Volume: 80, Issue:19

    Topics: Animals; Apoptosis Regulatory Proteins; Azoxymethane; Bone Marrow Transplantation; CD4-Positive T-Lymphocytes; Chemokine CCL5; Chemokine CXCL5; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Humans; Inflammatory Bowel Diseases; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Male; Mice, Inbred C57BL; Mice, Knockout; Muscle Proteins; Ubiquitination

2020
Cyclic derivative of morphiceptin Dmt-cyclo-(D-Lys-Phe-D-Pro-Asp)-NH2(P-317), a mixed agonist of MOP and KOP opioid receptors, exerts anti-inflammatory and anti-tumor activity in colitis and colitis-associated colorectal cancer in mice.
    European journal of pharmacology, 2020, Oct-15, Volume: 885

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Azoxymethane; Carcinogens; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Endorphins; Male; Mice; Mice, Inbred BALB C; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tumor Necrosis Factor-alpha

2020
Streptococcus thermophilus Inhibits Colorectal Tumorigenesis Through Secreting β-Galactosidase.
    Gastroenterology, 2021, Volume: 160, Issue:4

    Topics: Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; Bacterial Proteins; beta-Galactosidase; Cell Line, Tumor; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; Humans; Intestinal Mucosa; Male; Mice; Mice, Transgenic; Neoplasms, Experimental; Probiotics; Streptococcus thermophilus

2021
Toll-like receptor 4 prevents AOM/DSS-induced colitis-associated colorectal cancer in Bacteroides fragilis gnotobiotic mice.
    Human & experimental toxicology, 2021, Volume: 40, Issue:4

    Topics: Animals; Azoxymethane; Bacteroides fragilis; beta Catenin; Colitis; Colitis-Associated Neoplasms; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Disease Models, Animal; Germ-Free Life; Male; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type II; Proliferating Cell Nuclear Antigen; Toll-Like Receptor 4

2021
The Interplay Between Innate Immunity (TLR-4) and sCD40L in the Context of an Animal Model of Colitis-associated Cancer.
    Anticancer research, 2020, Volume: 40, Issue:10

    Topics: Animals; Azoxymethane; CD40 Ligand; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Immunity, Innate; Mice; Mice, Knockout; Toll-Like Receptor 4

2020
17β-Estradiol strongly inhibits azoxymethane/dextran sulfate sodium-induced colorectal cancer development in Nrf2 knockout male mice.
    Biochemical pharmacology, 2020, Volume: 182

    Topics: Animals; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Estradiol; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2

2020
The Fragile X Mental Retardation Protein Regulates RIPK1 and Colorectal Cancer Resistance to Necroptosis.
    Cellular and molecular gastroenterology and hepatology, 2021, Volume: 11, Issue:2

    Topics: Animals; Azoxymethane; Carcinogenesis; Case-Control Studies; Cell Culture Techniques; Cell Line, Tumor; Colon; Colorectal Neoplasms; Datasets as Topic; Disease-Free Survival; Fragile X Mental Retardation Protein; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Healthy Volunteers; Humans; Male; Mice; Mice, Knockout; Necroptosis; Neoplasm Recurrence, Local; Neoplasms, Experimental; Organoids; Prognosis; Receptor-Interacting Protein Serine-Threonine Kinases

2021
Behaviour of citrus pectin and modified citrus pectin in an azoxymethane/dextran sodium sulfate (AOM/DSS)-induced rat colorectal carcinogenesis model.
    International journal of biological macromolecules, 2021, Jan-15, Volume: 167

    Topics: Acetates; Animals; Azoxymethane; Bifidobacterium; Blood Glucose; Body Weight; Butyrates; Carcinogenesis; Chromatography, High Pressure Liquid; Citrus; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Hydrogen-Ion Concentration; Lactic Acid; Lactobacillaceae; Male; Metagenomics; Pectins; Phylogeny; Propionates; Proteobacteria; Rats; Rats, Inbred F344; Triglycerides

2021
ARRB2 promotes colorectal cancer growth through triggering WTAP.
    Acta biochimica et biophysica Sinica, 2021, Jan-12, Volume: 53, Issue:1

    Topics: Animals; Azoxymethane; beta-Arrestin 2; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Databases, Genetic; Dextran Sulfate; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Kaplan-Meier Estimate; Male; Mice, Nude; RNA Splicing Factors; Up-Regulation

2021
lncRNA GAS5 inhibits malignant progression by regulating macroautophagy and forms a negative feedback regulatory loop with the miR‑34a/mTOR/SIRT1 pathway in colorectal cancer.
    Oncology reports, 2021, Volume: 45, Issue:1

    Topics: Aged; Animals; Azoxymethane; Cell Line, Tumor; Colon; Colorectal Neoplasms; Feedback, Physiological; Female; Gene Expression Regulation, Neoplastic; Humans; Macroautophagy; Male; MicroRNAs; Middle Aged; Neoplasms, Experimental; Rats; RNA, Long Noncoding; Signal Transduction; Sirolimus; Sirtuin 1; TOR Serine-Threonine Kinases

2021
Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis.
    Scientific reports, 2021, 01-12, Volume: 11, Issue:1

    Topics: Acrolein; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred A; RNA-Binding Proteins

2021
Glutathione transferase Omega 1 confers protection against azoxymethane-induced colorectal tumour formation.
    Carcinogenesis, 2021, 06-21, Volume: 42, Issue:6

    Topics: Animals; Azoxymethane; Carcinogens; Carrier Proteins; Colitis; Colorectal Neoplasms; Dextran Sulfate; Glutathione Transferase; Inflammation; Interleukin-18; Interleukin-1beta; Mice; Mice, Inbred C57BL; Mice, Knockout

2021
Vitexin prevents colitis-associated carcinogenesis in mice through regulating macrophage polarization.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 83

    Topics: Animals; Anticarcinogenic Agents; Apigenin; Azoxymethane; Carcinogenesis; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Inflammatory Bowel Diseases; Macrophages; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III

2021
Induction of colitis-associated neoplasia in mice using azoxymethane and dextran sodium sulfate.
    Methods in cell biology, 2021, Volume: 163

    Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Mice; Mice, Inbred C57BL; Sulfates

2021
Co-administration of 5FU and propolis on AOM/DSS induced colorectal cancer in BALB-c mice.
    Life sciences, 2021, Jul-01, Volume: 276

    Topics: Animals; Anti-Infective Agents; Antimetabolites, Antineoplastic; Azoxymethane; Carcinogens; Colorectal Neoplasms; Dextran Sulfate; Drug Therapy, Combination; Fluorouracil; Male; Mice; Mice, Inbred BALB C; Propolis

2021
Glycyrrhizin Attenuates Carcinogenesis by Inhibiting the Inflammatory Response in a Murine Model of Colorectal Cancer.
    International journal of molecular sciences, 2021, Mar-05, Volume: 22, Issue:5

    Topics: Animals; Azoxymethane; Carcinogenesis; Colon; Colorectal Neoplasms; Disease Models, Animal; Female; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Interleukin-6; Mice; Mice, Inbred ICR; NF-kappa B; Signal Transduction; Tumor Necrosis Factor-alpha

2021
Shinan Sea Salt Intake Ameliorates Colorectal Cancer in AOM/DSS with High Fat Diet-Induced C57BL/6N Mice.
    Journal of medicinal food, 2021, Volume: 24, Issue:4

    Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Diet, High-Fat; Mice; Mice, Inbred C57BL; Republic of Korea; Sodium Chloride, Dietary

2021
An Optimized Protocol of Azoxymethane-Dextran Sodium Sulfate Induced Colorectal Tumor Model in Mice.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2019, Nov-12, Volume: 34, Issue:4

    Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Body Weight; Carcinogenesis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Male; Mice, Inbred C57BL

2019
Cardamonin Attenuates Experimental Colitis and Associated Colorectal Cancer.
    Biomolecules, 2021, 04-29, Volume: 11, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Azoxymethane; Cell Proliferation; Cell Survival; Chalcones; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Mice; MicroRNAs; Nitrous Oxide; RAW 264.7 Cells; Sequence Analysis, RNA; Signal Transduction; THP-1 Cells

2021
γδ T Cells Control Gut Pathology in a Chronic Inflammatory Model of Colorectal Cancer.
    Cellular and molecular gastroenterology and hepatology, 2021, Volume: 12, Issue:3

    Topics: Animals; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Intraepithelial Lymphocytes; Mice; Receptors, Antigen, T-Cell

2021
Galectin-1 fosters an immunosuppressive microenvironment in colorectal cancer by reprogramming CD8
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 05-25, Volume: 118, Issue:21

    Topics: Adenocarcinoma; Animals; Atlases as Topic; Azoxymethane; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Colitis; Colorectal Neoplasms; Computational Biology; Dextran Sulfate; Disease Models, Animal; Galectin 1; Gene Expression Regulation, Neoplastic; Humans; Interleukin-2 Receptor beta Subunit; Mice; Mice, Knockout; Programmed Cell Death 1 Receptor; Signal Transduction; Survival Analysis; T-Lymphocytes, Regulatory; Tumor Burden

2021
Limonin modulated immune and inflammatory responses to suppress colorectal adenocarcinoma in mice model.
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:9

    Topics: Adenocarcinoma; Animals; Antioxidants; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Limonins; Male; Mice; Mice, Inbred BALB C; Oxidative Stress

2021
A synthetic probiotic engineered for colorectal cancer therapy modulates gut microbiota.
    Microbiome, 2021, 05-26, Volume: 9, Issue:1

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Mice; Mice, Inbred C57BL; Probiotics

2021
Chemoprotective Effects of Geraniin against Azoxymethane Induced Colorectal Cancer by Reduction of Inflammatory Reaction.
    Journal of oleo science, 2021, Volume: 70, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Azoxymethane; Body Weight; Colorectal Neoplasms; Cytokines; Enzymes; Female; Glucosides; Hydrolyzable Tannins; Inflammation; Male; Oxidative Stress; Rats, Wistar

2021
Mice with dysfunctional TGF-β signaling develop altered intestinal microbiome and colorectal cancer resistant to 5FU.
    Biochimica et biophysica acta. Molecular basis of disease, 2021, 10-01, Volume: 1867, Issue:10

    Topics: Animals; Antineoplastic Agents; Azoxymethane; Colon; Colorectal Neoplasms; Dextran Sulfate; Female; Fluorouracil; Gastrointestinal Microbiome; Male; Mice; Mice, Inbred C57BL; Signal Transduction; Smad4 Protein; Transforming Growth Factor beta

2021
Mitochondrial DNA Integrity Is Maintained by APE1 in Carcinogen-Induced Colorectal Cancer.
    Molecular cancer research : MCR, 2017, Volume: 15, Issue:7

    Topics: Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Disease Models, Animal; DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA, Mitochondrial; Genome, Mitochondrial; Humans; Mice; Mice, Transgenic

2017
EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients.
    Gastroenterology, 2017, Volume: 153, Issue:1

    Topics: Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Epithelial Cells; ErbB Receptors; Humans; Inhibitor of Apoptosis Proteins; Interleukin-6; Intestinal Mucosa; Kaplan-Meier Estimate; Mice; Myeloid Cells; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Repressor Proteins; Signal Transduction; STAT3 Transcription Factor; Survival Rate; Survivin; Tumor Burden

2017
Expression of A-kinase anchor protein 13 and Rho-associated coiled-coil containing protein kinase in restituted and regenerated mucosal epithelial cells following mucosal injury and colorectal cancer cells in mouse models.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2017, Sep-05, Volume: 69, Issue:7

    Topics: A Kinase Anchor Proteins; Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Guanine Nucleotide Exchange Factors; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Minor Histocompatibility Antigens; Regeneration; rho-Associated Kinases; Wound Healing

2017
Sildenafil Suppresses Inflammation-Driven Colorectal Cancer in Mice.
    Cancer prevention research (Philadelphia, Pa.), 2017, Volume: 10, Issue:7

    Topics: Administration, Oral; Animals; Apoptosis; Azoxymethane; Carcinogenesis; Colitis; Colon; Colorectal Neoplasms; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dextran Sulfate; Humans; Immunohistochemistry; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Phosphodiesterase 5 Inhibitors; Polyps; Signal Transduction; Sildenafil Citrate

2017
Intermittent Dosing with Sulindac Provides Effective Colorectal Cancer Chemoprevention in the Azoxymethane-Treated Mouse Model.
    Cancer prevention research (Philadelphia, Pa.), 2017, Volume: 10, Issue:8

    Topics: Animals; Antineoplastic Agents; Azoxymethane; Carcinogens; Chemoprevention; Colorectal Neoplasms; Disease Models, Animal; Female; Mice; Sulindac

2017
Curcumin and Salsalate Suppresses Colonic Inflammation and Procarcinogenic Signaling in High-Fat-Fed, Azoxymethane-Treated Mice.
    Journal of agricultural and food chemistry, 2017, Aug-23, Volume: 65, Issue:33

    Topics: Animals; Anti-Inflammatory Agents; Azoxymethane; Colorectal Neoplasms; Curcumin; Diet, High-Fat; Humans; Interleukin-6; Male; Mice; NF-kappa B; Salicylates

2017
Effect of Angelica sinensis Root Extract on Cancer Prevention in Different Stages of an AOM/DSS Mouse Model.
    International journal of molecular sciences, 2017, Aug-11, Volume: 18, Issue:8

    Topics: Angelica sinensis; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; DNA Damage; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred BALB C; Plant Extracts; Plant Roots; Reactive Oxygen Species; Tumor Suppressor Protein p53

2017
Gavage of Fecal Samples From Patients With Colorectal Cancer Promotes Intestinal Carcinogenesis in Germ-Free and Conventional Mice.
    Gastroenterology, 2017, Volume: 153, Issue:6

    Topics: Animals; Azoxymethane; Case-Control Studies; Cell Proliferation; Cell Transformation, Neoplastic; Colon; Colonic Polyps; Colorectal Neoplasms; Disease Models, Animal; Feces; Gastrointestinal Microbiome; Gene Expression Regulation, Neoplastic; Germ-Free Life; Host-Pathogen Interactions; Humans; Inflammation Mediators; Ki-67 Antigen; Lymphocytes, Tumor-Infiltrating; Male; Mice, Inbred C57BL; Th1 Cells; Th17 Cells

2017
Macrophage depletion using clodronate liposomes decreases tumorigenesis and alters gut microbiota in the AOM/DSS mouse model of colon cancer.
    American journal of physiology. Gastrointestinal and liver physiology, 2018, 01-01, Volume: 314, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Biomarkers, Tumor; Cell Transformation, Neoplastic; Clodronic Acid; Colon; Colonic Polyps; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Host-Pathogen Interactions; Inflammation Mediators; Liposomes; Macrophages; Male; Mice, Inbred C57BL; Signal Transduction; Time Factors; Tumor Burden

2018
MicroRNAs 15A and 16-1 Activate Signaling Pathways That Mediate Chemotaxis of Immune Regulatory B cells to Colorectal Tumors.
    Gastroenterology, 2018, Volume: 154, Issue:3

    Topics: Animals; Azoxymethane; B-Lymphocytes, Regulatory; Cell Proliferation; Chemokine CXCL10; Chemokine CXCL9; Chemotaxis, Leukocyte; Colorectal Neoplasms; Dextran Sulfate; Gene Expression Regulation, Neoplastic; Genotype; Humans; I-kappa B Kinase; Lymphocytes, Tumor-Infiltrating; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; NF-kappa B; Phenotype; Signal Transduction; STAT1 Transcription Factor; Time Factors; Tumor Burden; Tumor Escape

2018
Combination Strategy of Quantitative Proteomics Uncovers the Related Proteins of Colorectal Cancer in the Interstitial Fluid of Colonic Tissue from the AOM-DSS Mouse Model.
    Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1788

    Topics: Animals; Azoxymethane; Biomarkers, Tumor; Blood Proteins; Chromatography, Liquid; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Extracellular Fluid; Humans; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Proteome; Proteomics; Tumor Microenvironment

2018
Chemopreventive effects of Ku-jin tea against AOM-induced precancerous colorectal lesions in rats and metabolomic analysis.
    Scientific reports, 2017, Nov-21, Volume: 7, Issue:1

    Topics: Animals; Azoxymethane; Body Weight; Chemoprevention; Colon; Colorectal Neoplasms; Cytokines; Discriminant Analysis; Immunologic Factors; Least-Squares Analysis; Male; Metabolic Networks and Pathways; Metabolomics; Precancerous Conditions; Rats, Wistar; Tea

2017
Inhibition of MK2 suppresses IL-1β, IL-6, and TNF-α-dependent colorectal cancer growth.
    International journal of cancer, 2018, 04-15, Volume: 142, Issue:8

    Topics: Animals; Azoxymethane; Cell Line, Tumor; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Female; Inflammation; Interleukin-1beta; Interleukin-6; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Protein Serine-Threonine Kinases; Signal Transduction; Tumor Necrosis Factor-alpha

2018
The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.
    Oncogene, 2018, Volume: 37, Issue:9

    Topics: Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Cancer-Associated Fibroblasts; Carcinogenesis; Cell Proliferation; Coculture Techniques; Colorectal Neoplasms; Cytoskeletal Proteins; DNA-Binding Proteins; Fibroblasts; Humans; Intracellular Signaling Peptides and Proteins; LIM Domain Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prognosis; Protein-Lysine 6-Oxidase; Signal Transduction; Stromal Cells; Tumor Cells, Cultured

2018
Methylglyoxal displays colorectal cancer-promoting properties in the murine models of azoxymethane and CT26 isografts.
    Free radical biology & medicine, 2018, 02-01, Volume: 115

    Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Cell Line; Cholesterol, LDL; Colorectal Neoplasms; Disease Models, Animal; Humans; Inflammation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Oxidative Stress; Precancerous Conditions; Pyruvaldehyde; Transplantation, Isogeneic

2018
Pretreatment with probiotic Bifico ameliorates colitis-associated cancer in mice: Transcriptome and gut flora profiling.
    Cancer science, 2018, Volume: 109, Issue:3

    Topics: Administration, Oral; Animals; Azoxymethane; Bacteria; Chemokines, CXC; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Gene Expression Profiling; Humans; Male; Mice; Mice, Inbred C57BL; Probiotics; RNA, Ribosomal, 16S; Signal Transduction; Xenograft Model Antitumor Assays

2018
Structural shift of gut microbiota during chemo-preventive effects of epigallocatechin gallate on colorectal carcinogenesis in mice.
    World journal of gastroenterology, 2017, Dec-14, Volume: 23, Issue:46

    Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Carcinogens; Catechin; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Microbiome; Humans; Mice; Rectum; RNA, Ribosomal, 16S

2017
Elevated d-2-hydroxyglutarate during colitis drives progression to colorectal cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 01-30, Volume: 115, Issue:5

    Topics: Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Biopsy; Caco-2 Cells; Cell Movement; Cell Proliferation; Cell Survival; Colitis; Colitis, Ulcerative; Colorectal Neoplasms; Dextran Sulfate; Disease Progression; Glutarates; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Intestinal Mucosa; Mice; Risk

2018
Chemoprevention of colorectal cancer by black raspberry anthocyanins involved the modulation of gut microbiota and SFRP2 demethylation.
    Carcinogenesis, 2018, 03-08, Volume: 39, Issue:3

    Topics: Animals; Anthocyanins; Azoxymethane; Chemoprevention; Colorectal Neoplasms; Demethylation; Dextran Sulfate; DNA Methylation; Gastrointestinal Microbiome; Membrane Proteins; Mice; Mice, Inbred C57BL; Phytochemicals; Rubus

2018
Physicochemical and nutraceutical properties of moringa (Moringa oleifera) leaves and their effects in an in vivo AOM/DSS-induced colorectal carcinogenesis model.
    Food research international (Ottawa, Ont.), 2018, Volume: 105

    Topics: Animals; Antioxidants; Azoxymethane; beta-Glucosidase; Chemical Phenomena; Colorectal Neoplasms; Diet Therapy; Dietary Fiber; Dietary Supplements; Disease Models, Animal; Feces; Glucuronidase; Male; Mice; Moringa oleifera; Phenols; Phytochemicals; Plant Extracts; Plant Leaves; Tryptophanase; Urease

2018
Chemopreventive Effect of Aster glehni on Inflammation-Induced Colorectal Carcinogenesis in Mice.
    Nutrients, 2018, Feb-12, Volume: 10, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Aster Plant; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dextran Sulfate; Inflammation; Interleukins; Male; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Spleen; Tumor Necrosis Factor-alpha

2018
Natural dietary compound naringin prevents azoxymethane/dextran sodium sulfate-induced chronic colorectal inflammation and carcinogenesis in mice.
    Cancer biology & therapy, 2018, 08-03, Volume: 19, Issue:8

    Topics: Animals; Autophagy; Azoxymethane; Biomarkers; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cytokines; Dietary Supplements; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Flavanones; Inflammation Mediators; Intestinal Mucosa; Male; Mice; Sulfates

2018
Chemopreventive Effects of Edible Canna (Canna edulis Kerr.) Against Colorectal Carcinogenesis: Effects on Expression of Adenomatous Polyposis Coli and Inducible Nitric Oxide Synthase in Rat Inflammatory Model
    Asian Pacific journal of cancer prevention : APJCP, 2018, Mar-27, Volume: 19, Issue:3

    Topics: Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation; Male; Nitric Oxide Synthase Type II; Plant Extracts; Rats; Rats, Wistar; Zingiberales

2018
Methods for In Vivo Functional Studies of Chromatin-Modifying Enzymes in Early Steps of Colon Carcinogenesis.
    Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1765

    Topics: Animals; Azoxymethane; Benzeneacetamides; Carcinogenesis; Chromatin; Colon; Colorectal Neoplasms; Dextran Sulfate; DNA Helicases; DNA-Binding Proteins; Histones; Humans; Intestinal Mucosa; Lysine Acetyltransferase 5; Mice; Mice, Transgenic; Neoplasms, Experimental; Pyridines; Trans-Activators; Transcription Factors; Wnt Signaling Pathway

2018
Tea Polysaccharides Inhibit Colitis-Associated Colorectal Cancer via Interleukin-6/STAT3 Pathway.
    Journal of agricultural and food chemistry, 2018, May-02, Volume: 66, Issue:17

    Topics: Animals; Antineoplastic Agents, Phytogenic; Azoxymethane; Camellia sinensis; Cell Line, Tumor; Colitis; Colorectal Neoplasms; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Inflammation; Interleukin-6; Macrophages; Mice; Mice, Inbred BALB C; Polysaccharides; RAW 264.7 Cells; Signal Transduction; STAT3 Transcription Factor; Tea

2018
Short-chain fatty acids administration is protective in colitis-associated colorectal cancer development.
    The Journal of nutritional biochemistry, 2018, Volume: 57

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cecum; Cell Proliferation; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Fatty Acids, Volatile; Male; Mice, Inbred BALB C; NF-kappa B; Receptors, G-Protein-Coupled

2018
Vanillin-Ameliorated Development of Azoxymethane/Dextran Sodium Sulfate-Induced Murine Colorectal Cancer: The Involvement of Proteasome/Nuclear Factor-κB/Mitogen-Activated Protein Kinase Pathways.
    Journal of agricultural and food chemistry, 2018, Jun-06, Volume: 66, Issue:22

    Topics: Animals; Azoxymethane; Benzaldehydes; Colorectal Neoplasms; Dextran Sulfate; Female; Humans; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-kappa B; Proteasome Endopeptidase Complex; Signal Transduction

2018
Tumor Necrosis Factor Ligand-Related Molecule 1A Regulates the Occurrence of Colitis-Associated Colorectal Cancer.
    Digestive diseases and sciences, 2018, Volume: 63, Issue:9

    Topics: Animals; Azoxymethane; beta Catenin; Cell Movement; Cell Proliferation; Colitis; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Invasiveness; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myc; Time Factors; Tumor Necrosis Factor Ligand Superfamily Member 15; Wnt Signaling Pathway

2018
The protective effects of fermented kefir milk on azoxymethane-induced aberrant crypt formation in mice colon.
    Tissue & cell, 2018, Volume: 52

    Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Female; Kefir; Mice; Mice, Inbred BALB C

2018
Dro1/Ccdc80 inactivation promotes AOM/DSS-induced colorectal carcinogenesis and aggravates colitis by DSS in mice.
    Carcinogenesis, 2018, 09-21, Volume: 39, Issue:9

    Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Epithelial-Mesenchymal Transition; Extracellular Matrix Proteins; Genes, Tumor Suppressor; Glycoproteins; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout

2018
Peritoneal lavage with povidone-iodine solution in colorectal cancer-induced rats.
    The Journal of surgical research, 2018, Volume: 228

    Topics: Acidosis; Animals; Anti-Infective Agents, Local; Azoxymethane; Bacterial Translocation; Colorectal Neoplasms; Dextran Sulfate; Endotoxins; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Male; Microscopy, Electron, Transmission; Neoplasms, Experimental; Peritoneal Absorption; Peritoneal Lavage; Permeability; Povidone-Iodine; Rats; Rats, Sprague-Dawley; Shock, Septic; Tight Junctions

2018
Over-expressed miRNA-200b ameliorates ulcerative colitis-related colorectal cancer in mice through orchestrating epithelial-mesenchymal transition and inflammatory responses by channel of AKT2.
    International immunopharmacology, 2018, Volume: 61

    Topics: 3' Untranslated Regions; Animals; Azoxymethane; Cells, Cultured; Colitis, Ulcerative; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Epithelial-Mesenchymal Transition; Genetic Therapy; Humans; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Proto-Oncogene Proteins c-akt; Signal Transduction; Transgenes; Tumor Necrosis Factor-alpha

2018
MicroRNA‑449a is a potential predictor of colitis‑associated colorectal cancer progression.
    Oncology reports, 2018, Volume: 40, Issue:3

    Topics: Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Carcinogens; Case-Control Studies; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Progression; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Prognosis; Receptor, Notch1; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2018
Deletion of cadherin-17 enhances intestinal permeability and susceptibility to intestinal tumour formation.
    The Journal of pathology, 2018, Volume: 246, Issue:3

    Topics: Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Adenoma; Animals; Azoxymethane; Cadherins; Carcinoma; Cell Cycle Proteins; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Deletion; Genetic Predisposition to Disease; Intestinal Absorption; Intestinal Mucosa; Mice, Inbred C57BL; Mice, Knockout; Permeability; Phenotype; Phosphoproteins; Signal Transduction; Tumor Suppressor Proteins; YAP-Signaling Proteins

2018
Effect of Estradiol in an Azoxymethane/Dextran Sulfate Sodium-Treated Mouse Model of Colorectal Cancer: Implication for Sex Difference in Colorectal Cancer Development.
    Cancer research and treatment, 2019, Volume: 51, Issue:2

    Topics: Animals; Azoxymethane; Biomarkers; Biopsy; Carcinogens; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Disease Progression; Disease Susceptibility; Estradiol; Female; Humans; Immunohistochemistry; Inflammation Mediators; Male; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Sex Factors

2019
Chemoprevention of inflammation-related colorectal cancer by silymarin-, acetyl-11-keto-beta-boswellic acid-, curcumin- and maltodextrin-enriched dietetic formulation in animal model.
    Carcinogenesis, 2018, 10-08, Volume: 39, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Azoxymethane; Chemoprevention; Colitis; Colon; Colonoscopy; Colorectal Neoplasms; Curcumin; Cytokines; Dextran Sulfate; Disease Models, Animal; Food, Fortified; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Polysaccharides; Real-Time Polymerase Chain Reaction; Receptors, Estrogen; Silymarin; Triterpenes

2018
Deceleration of glycometabolism impedes IgG-producing B-cell-mediated tumor elimination by targeting SATB1.
    Immunology, 2019, Volume: 156, Issue:1

    Topics: Adenocarcinoma; Aged; Animals; Azoxymethane; B-Lymphocytes; Cells, Cultured; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Glucose; Humans; Immunoglobulin G; Lung Neoplasms; Male; Matrix Attachment Region Binding Proteins; Mice; Mice, Inbred C57BL; Neoplasms; Promoter Regions, Genetic; RNA, Small Interfering; STAT6 Transcription Factor

2019
Dietary Supplementation of Selenoneine-Containing Tuna Dark Muscle Extract Effectively Reduces Pathology of Experimental Colorectal Cancers in Mice.
    Nutrients, 2018, 09-27, Volume: 10, Issue:10

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Colitis; Colorectal Neoplasms; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Histidine; Mice; Muscles; Organoselenium Compounds; Spleen; Tuna

2018
Single probiotic supplement suppresses colitis-associated colorectal tumorigenesis by modulating inflammatory development and microbial homeostasis.
    Journal of gastroenterology and hepatology, 2019, Volume: 34, Issue:7

    Topics: Animals; Apoptosis; Azoxymethane; Caco-2 Cells; Cell Proliferation; Coculture Techniques; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Dysbiosis; Gastrointestinal Microbiome; Humans; Inflammation Mediators; Intestines; Lactobacillus helveticus; Male; Mice; Mice, Inbred C57BL; Probiotics; RAW 264.7 Cells; T-Lymphocytes

2019
Effects of Grape Juice in Superoxide Dismutase and Catalase in Colorectal Cancer Carcinogenesis Induced by Azoxymethane
    Asian Pacific journal of cancer prevention : APJCP, 2018, Oct-26, Volume: 19, Issue:10

    Topics: Animals; Antioxidants; Azoxymethane; Carcinogenesis; Carcinogens; Catalase; Colorectal Neoplasms; Fruit and Vegetable Juices; Intestinal Mucosa; Male; Oxidants; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Vitis

2018
Mouse Model of Colitis-Associated Colorectal Cancer (CAC): Isolation and Characterization of Mucosal-Associated Lymphoid Cells.
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1884

    Topics: Animals; Azoxymethane; Cell Separation; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Colitis, Ulcerative; Colon; Colorectal Neoplasms; Dextran Sulfate; Flow Cytometry; Humans; Intestinal Mucosa; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms, Experimental

2019
Administration of High-Dose Vitamin C and Irinotecan Ameliorates Colorectal Cancer Induced by Azoxymethane and Dextran Sodium Sulfate in Mice.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Dose-Response Relationship, Drug; Drug Synergism; Interleukin-6; Irinotecan; Male; Mice, Hairless; Reactive Oxygen Species

2018
Glucocorticoids promote the development of azoxymethane and dextran sulfate sodium-induced colorectal carcinoma in mice.
    BMC cancer, 2019, Jan-21, Volume: 19, Issue:1

    Topics: Animals; Azoxymethane; Carcinogenesis; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Drug Synergism; Glucocorticoids; Humans; Immunohistochemistry; Ki-67 Antigen; Male; Mice, Inbred C57BL; Proliferating Cell Nuclear Antigen; Transcription Factor RelA

2019
The Azoxymethane/Il10
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1960

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Disease Models, Animal; Germ-Free Life; Inflammation; Inflammatory Bowel Diseases; Interleukin-10; Intestines; Mice, Knockout

2019
Impact of 5 fluorouracil chemotherapy on gut inflammation, functional parameters, and gut microbiota.
    Brain, behavior, and immunity, 2019, Volume: 80

    Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Fecal Microbiota Transplantation; Fluorouracil; Gastrointestinal Microbiome; Inflammation; Male; Mice; Mice, Inbred C57BL

2019
Gum arabic and red propolis protecteting colorectal preneoplastic lesions in a rat model of azoxymethane1.
    Acta cirurgica brasileira, 2019, Feb-28, Volume: 34, Issue:2

    Topics: Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Disease Models, Animal; Gum Arabic; Lysine; Male; Oxidative Stress; Precancerous Conditions; Propolis; Rats; Rats, Wistar

2019
Cancer testis antigen 55 deficiency attenuates colitis-associated colorectal cancer by inhibiting NF-κB signaling.
    Cell death & disease, 2019, 04-03, Volume: 10, Issue:4

    Topics: Animals; Antigens, Neoplasm; Azoxymethane; Carcinogenesis; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; HCT116 Cells; HEK293 Cells; Humans; I-kappa B Kinase; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; NF-kappa B; Phosphorylation; Signal Transduction; Tumor Necrosis Factor-alpha

2019
Epidermal growth factor receptor-targeted molecular imaging of colorectal tumors: Detection and treatment evaluation of tumors in animal models.
    Cancer science, 2019, Volume: 110, Issue:6

    Topics: Animals; Antineoplastic Agents; Azoxymethane; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; ErbB Receptors; Female; Fluorouracil; HT29 Cells; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; Rats, Inbred F344; Xenograft Model Antitumor Assays

2019
Effects of 17β-estradiol on colorectal cancer development after azoxymethane/dextran sulfate sodium treatment of ovariectomized mice.
    Biochemical pharmacology, 2019, Volume: 164

    Topics: Animals; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Estradiol; Female; Mice; Mice, Inbred ICR; Ovariectomy; Random Allocation

2019
The diagnostic efficacy of circulating miRNAs in monitoring the early development of colitis-induced colorectal cancer.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:10

    Topics: Animals; Azoxymethane; Circulating MicroRNA; Colitis; Colorectal Neoplasms; Dextran Sulfate; Gene Expression Regulation, Neoplastic; Male; Mice; Neoplasms, Experimental

2019
Interleukin-13 and its signaling pathway is associated with obesity-related colorectal tumorigenesis.
    Cancer science, 2019, Volume: 110, Issue:7

    Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Interleukin-13; Mice; Mice, Inbred C57BL; Obesity; Peritoneal Absorption; Receptors, Interleukin-13; Signal Transduction; Up-Regulation

2019
Role of Lymphatic Deficiency in the Pathogenesis and Progression of Inflammatory Bowel Disease to Colorectal Cancer in an Experimental Mouse Model.
    Inflammatory bowel diseases, 2019, 11-14, Volume: 25, Issue:12

    Topics: Angiopoietin-2; Animals; Azoxymethane; Biomarkers; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Progression; Female; Inflammatory Bowel Diseases; Lymphangiogenesis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Tumor Necrosis Factor-alpha

2019
Peptide TNIIIA2 Derived from Tenascin-C Contributes to Malignant Progression in Colitis-Associated Colorectal Cancer via β1-Integrin Activation in Fibroblasts.
    International journal of molecular sciences, 2019, Jun-05, Volume: 20, Issue:11

    Topics: Animals; Azoxymethane; Caco-2 Cells; Cell Proliferation; Colitis; Colonic Polyps; Colorectal Neoplasms; Culture Media, Conditioned; Dextran Sulfate; Disease Models, Animal; Disease Progression; Epithelial Cells; Fibroblasts; Humans; Integrin beta1; Male; Mice, Inbred ICR; Paracrine Communication; Peptides; Tenascin

2019
Ilexgenin A prevents early colonic carcinogenesis and reprogramed lipid metabolism through HIF1α/SREBP-1.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 63

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; beta Catenin; Colitis; Colorectal Neoplasms; Dextran Sulfate; HCT116 Cells; HT29 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lipid Metabolism; Male; Mice, Inbred BALB C; Sterol Regulatory Element Binding Protein 1; Triterpenes; Tumor Necrosis Factor-alpha

2019
Induction of endoplasmic reticulum stress and inhibition of colon carcinogenesis by the anti-helmintic drug rafoxanide.
    Cancer letters, 2019, Oct-10, Volume: 462

    Topics: Aged; Animals; Antinematodal Agents; Apoptosis; Azoxymethane; Carcinogens; Cell Proliferation; Colonic Neoplasms; Colorectal Neoplasms; Endoplasmic Reticulum Stress; Female; Humans; Male; Mice; Rafoxanide; Tumor Cells, Cultured

2019
Inhibitory role of Gas6 in intestinal tumorigenesis.
    Carcinogenesis, 2013, Volume: 34, Issue:7

    Topics: Aged; Aged, 80 and over; Animals; Azoxymethane; Bone Marrow; Bone Marrow Transplantation; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Progression; Female; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Intercellular Signaling Peptides and Proteins; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Monocytes; NF-kappa B; Prognosis; Recombinant Proteins; RNA, Messenger; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins

2013
Chemopreventive effect of dietary glutamine on colitis-associated colon tumorigenesis in mice.
    Carcinogenesis, 2013, Volume: 34, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azoxymethane; Biomarkers, Tumor; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Colitis; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Dietary Supplements; Enzyme-Linked Immunosorbent Assay; Female; Glutamine; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide Synthase Type II; Real-Time Polymerase Chain Reaction; Rectum; Severity of Illness Index

2013
Discovery of potential targets of selenomethionine-mediated chemoprevention in colorectal carcinoma mouse model using proteomics analysis.
    Carcinogenesis, 2013, Volume: 34, Issue:7

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; C-Reactive Protein; Chemoprevention; Colonic Polyps; Colorectal Neoplasms; Deoxyguanosine; Dextran Sulfate; Drug Screening Assays, Antitumor; Electrophoresis, Gel, Two-Dimensional; Immunohistochemistry; Male; Mice; Mice, Inbred ICR; Neoplasm Proteins; Oxidative Stress; Prohibitins; Protein Interaction Maps; Proteome; Proteomics; Repressor Proteins; Selenomethionine; Software

2013
Ay allele promotes azoxymethane-induced colorectal carcinogenesis by macrophage migration in hyperlipidemic/diabetic KK mice.
    Cancer science, 2013, Volume: 104, Issue:7

    Topics: Alleles; Animals; Azoxymethane; beta Catenin; Carcinogenesis; Cell Movement; Cocarcinogenesis; Colorectal Neoplasms; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Hyperlipidemias; Inflammation; Insulin; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Inbred NOD; RNA, Messenger; Triglycerides

2013
Colitis-accelerated colorectal cancer and metabolic dysregulation in a mouse model.
    Carcinogenesis, 2013, Volume: 34, Issue:8

    Topics: Animals; Apoptosis; Azoxymethane; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Inflammation; Metabolic Diseases; Mice; Mice, Inbred BALB C; MicroRNAs; RNA, Messenger; Transcriptome; Up-Regulation; Wnt Proteins

2013
Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.
    Cancer cell, 2013, May-13, Volume: 23, Issue:5

    Topics: Animals; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; DNA Damage; Genetic Predisposition to Disease; Histones; Humans; Mice; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Protein Isoforms; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53

2013
Combination of selenium and green tea improves the efficacy of chemoprevention in a rat colorectal cancer model by modulating genetic and epigenetic biomarkers.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Acetylation; Administration, Oral; Animals; Anticarcinogenic Agents; Azoxymethane; Cell Proliferation; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase 2; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Epigenesis, Genetic; Genetic Markers; Histones; Ki-67 Antigen; Male; Plant Extracts; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Selenium; Tumor Burden

2013
Suppressive effect of RAS inhibitor manumycin A on aberrant crypt foci formation in the azoxymethane-induced rat colorectal carcinogenesis model.
    Journal of gastroenterology and hepatology, 2013, Volume: 28, Issue:10

    Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Colorectal Neoplasms; Disease Models, Animal; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Farnesyltranstransferase; Genes, ras; Injections, Subcutaneous; Ki-67 Antigen; Mutation; Phosphorylation; Polyenes; Polyunsaturated Alkamides; ras Proteins; Rats; Rats, Inbred F344

2013
Role of anthocyanin-enriched purple-fleshed sweet potato p40 in colorectal cancer prevention.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:11

    Topics: Aberrant Crypt Foci; Animals; Anthocyanins; Antineoplastic Agents; Antioxidants; Azoxymethane; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Dietary Fiber; Epithelial Cells; Female; Glucosides; Humans; Immunohistochemistry; Ipomoea batatas; Mice; Phenols; Plant Extracts; Proliferating Cell Nuclear Antigen

2013
Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and β-catenin.
    Cancer research, 2013, Sep-01, Volume: 73, Issue:17

    Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Blotting, Western; Cell Nucleus; Cell Proliferation; Colorectal Neoplasms; CSK Tyrosine-Protein Kinase; Dextran Sulfate; Humans; Immunoenzyme Techniques; Male; Mice; Phytotherapy; Plant Extracts; Protein Transport; Quercetin; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; src-Family Kinases; Tumor Cells, Cultured

2013
Effects of dark chocolate on azoxymethane-induced colonic aberrant crypt foci.
    Nutrition and cancer, 2013, Volume: 65, Issue:5

    Topics: Aberrant Crypt Foci; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Azoxymethane; Cacao; Candy; Carcinogens; Cell Proliferation; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Down-Regulation; Male; Plant Extracts; Polyphenols; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription Factor RelA

2013
Enhanced development of azoxymethane-induced colonic preneoplastic lesions in hypertensive rats.
    International journal of molecular sciences, 2013, Jul-15, Volume: 14, Issue:7

    Topics: Adipose Tissue; Angiotensin II; Animals; Azoxymethane; Carcinogens; Catalase; Chemokine CCL2; Colorectal Neoplasms; Cyclooxygenase 2; Glutathione Peroxidase; Hypertension; Insulin Resistance; Interleukin-6; Intestinal Mucosa; Male; Nitric Oxide Synthase Type II; Oxidative Stress; Precancerous Conditions; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Zucker; RNA, Messenger; Tumor Necrosis Factor-alpha

2013
Multiorgan anticarcinogenic effects of vanillin.
    Journal of medicinal food, 2013, Volume: 16, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Benzaldehydes; Colon; Colorectal Neoplasms; Gene Expression; Male

2013
Four jointed box 1 promotes angiogenesis and is associated with poor patient survival in colorectal carcinoma.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Animals; Azoxymethane; Cell Line; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Dextran Sulfate; Female; Humans; In Vitro Techniques; Mice; Mice, Nude; Neovascularization, Pathologic; Nerve Tissue Proteins

2013
Nano-architectural alterations in mucus layer fecal colonocytes in field carcinogenesis: potential for screening.
    Cancer prevention research (Philadelphia, Pa.), 2013, Volume: 6, Issue:10

    Topics: Adenoma; Animals; Azoxymethane; Carcinogenesis; Colon; Colonoscopy; Colorectal Neoplasms; Disease Models, Animal; Early Detection of Cancer; Endoscopy; Feces; Intestinal Mucosa; Male; Mass Screening; Microscopy; Occult Blood; Optics and Photonics; Rats; Rats, Inbred F344

2013
Pomegranate polyphenolics suppressed azoxymethane-induced colorectal aberrant crypt foci and inflammation: possible role of miR-126/VCAM-1 and miR-126/PI3K/AKT/mTOR.
    Carcinogenesis, 2013, Volume: 34, Issue:12

    Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Beverages; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; HT29 Cells; Humans; Inflammation; Lythraceae; Male; MicroRNAs; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinase; Polyphenols; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases; Vascular Cell Adhesion Molecule-1

2013
Comparing the effects of COX and non-COX-inhibiting NSAIDs on enhancement of apoptosis and inhibition of aberrant crypt foci formation in a rat colorectal cancer model.
    Anticancer research, 2013, Volume: 33, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azoxymethane; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Disease Models, Animal; Flurbiprofen; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Sulindac

2013
Luteolin, a bioflavonoid inhibits Azoxymethane-induced colorectal cancer through activation of Nrf2 signaling.
    Toxicology mechanisms and methods, 2014, Volume: 24, Issue:1

    Topics: Animals; Azoxymethane; Colorectal Neoplasms; Gene Expression Regulation; Luteolin; Male; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2

2014
Distribution of bone-marrow-derived endothelial and immune cells in a murine colitis-associated colorectal cancer model.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Animals; Azoxymethane; Bone Marrow Cells; Bone Marrow Transplantation; CD11c Antigen; CD4-Positive T-Lymphocytes; Cell Line; Colitis; Colorectal Neoplasms; Dendritic Cells; Dextran Sulfate; Endothelial Cells; Flow Cytometry; Green Fluorescent Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Platelet Endothelial Cell Adhesion Molecule-1

2013
3-aroylmethylene-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-ones as potent Nrf2/ARE inducers in human cancer cells and AOM-DSS treated mice.
    Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20

    Topics: Active Transport, Cell Nucleus; Adenoma; Animals; Antineoplastic Agents; Antioxidant Response Elements; Azoxymethane; Blotting, Western; Cell Nucleus; Colorectal Neoplasms; Dextran Sulfate; Female; Gene Expression Regulation, Neoplastic; HCT116 Cells; Heme Oxygenase-1; Hep G2 Cells; Heterocyclic Compounds, 3-Ring; Humans; Interleukin-1beta; Interleukin-6; Mice; Mice, Inbred C57BL; Models, Chemical; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Neoplasms; NF-E2-Related Factor 2

2013
CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis.
    Cancer cell, 2013, Nov-11, Volume: 24, Issue:5

    Topics: Adoptive Transfer; Animals; Azoxymethane; Carcinogenesis; CD8-Positive T-Lymphocytes; Cells, Cultured; Chemokine CXCL1; Chemotaxis; Colitis; Colorectal Neoplasms; Cytotoxicity, Immunologic; Dextran Sulfate; Dinoprostone; Humans; Inflammation Mediators; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Mice, Knockout; Myeloid Cells; Receptors, Interleukin-8B; Tumor Microenvironment

2013
Chemoprevention of colonic aberrant crypt foci by Gynura procumbens in rats.
    Journal of ethnopharmacology, 2014, Feb-12, Volume: 151, Issue:3

    Topics: Aberrant Crypt Foci; Animals; Antioxidants; Asteraceae; Azoxymethane; Carcinogens; Chemoprevention; Colon; Colorectal Neoplasms; Female; Glutathione Transferase; Male; Malondialdehyde; Phenols; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Toxicity Tests, Acute

2014
Characterization of hERG1 channel role in mouse colorectal carcinogenesis.
    Cancer medicine, 2013, Volume: 2, Issue:5

    Topics: Adenomatous Polyposis Coli; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colorectal Neoplasms; Disease Models, Animal; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Intestine, Large; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Proteins; Neovascularization, Pathologic; Piperidines; Proto-Oncogene Proteins c-akt; Pyridines; Vascular Endothelial Growth Factor A

2013
Biomarkers of coordinate metabolic reprogramming in colorectal tumors in mice and humans.
    Gastroenterology, 2014, Volume: 146, Issue:5

    Topics: Animals; Azoxymethane; Biomarkers, Tumor; Cell Proliferation; Chromatography, Reverse-Phase; Colorectal Neoplasms; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, APC; High-Throughput Screening Assays; Humans; Metabolomics; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Staging; Predictive Value of Tests; Protein Interaction Mapping; Protein Interaction Maps; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2014
CD24 knockout prevents colorectal cancer in chemically induced colon carcinogenesis and in APC(Min)/CD24 double knockout transgenic mice.
    International journal of cancer, 2014, Sep-01, Volume: 135, Issue:5

    Topics: Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; beta Catenin; Carcinogenesis; CD24 Antigen; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Dinoprostone; Disease Progression; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Promoter Regions, Genetic; Signal Transduction; Tumor Burden

2014
MyD88 adaptor-like (Mal) regulates intestinal homeostasis and colitis-associated colorectal cancer in mice.
    American journal of physiology. Gastrointestinal and liver physiology, 2014, May-01, Volume: 306, Issue:9

    Topics: Animals; Azoxymethane; Bone Marrow Transplantation; Caco-2 Cells; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Homeostasis; Humans; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Interleukin-1; Severity of Illness Index; Time Factors; Transplantation Chimera

2014
Chemopreventive evaluation of a Schiff base derived copper (II) complex against azoxymethane-induced colorectal cancer in rats.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Blood Chemical Analysis; Body Weight; Carcinogens; Chemoprevention; Colorectal Neoplasms; Copper; Disease Models, Animal; Female; Kidney; Liver; Male; Oxidation-Reduction; Proliferating Cell Nuclear Antigen; Rats; Schiff Bases; Toxicity Tests, Acute

2014
Characterization of azoxymethane-induced colon tumor metastasis to lung in a mouse model relevant to human sporadic colorectal cancer and evaluation of grape seed extract efficacy.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2014, Volume: 66, Issue:5-6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Azoxymethane; Colonic Neoplasms; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Grape Seed Extract; Humans; Lung; Lung Neoplasms; Male; Mice, Inbred Strains

2014
Identification of gene expression changes from colitis to CRC in the mouse CAC model.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Mice; Mice, Inbred BALB C; Protein Binding

2014
Enhanced chemopreventive effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer.
    Nitric oxide : biology and chemistry, 2014, Sep-15, Volume: 41

    Topics: Aberrant Crypt Foci; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Colon; Colorectal Neoplasms; Dinoprostone; Male; Mice; Naproxen; Protective Agents; Rats; Thromboxane B2

2014
Dynamic microbe and molecule networks in a mouse model of colitis-associated colorectal cancer.
    Scientific reports, 2014, May-15, Volume: 4

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Tract; Inflammation; Male; Mice; Mice, Inbred BALB C; RNA, Ribosomal, 16S

2014
Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice.
    Molecular carcinogenesis, 2015, Volume: 54, Issue:10

    Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Azoxymethane; Berberine; Carcinogenesis; Caspase 3; Cell Line, Tumor; Colon; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 2; eIF-2 Kinase; Female; HCT116 Cells; Humans; Mice; NF-kappa B; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53

2015
Nuclear adenomatous polyposis coli suppresses colitis-associated tumorigenesis in mice.
    Carcinogenesis, 2014, Volume: 35, Issue:8

    Topics: Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Azoxymethane; beta Catenin; Blotting, Western; Carcinogens; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Disease Models, Animal; Inflammation; Mice; Mutation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction

2014
Combinational chemoprevention effect of celecoxib and an oral antiangiogenic LHD4 on colorectal carcinogenesis in mice.
    Anti-cancer drugs, 2014, Volume: 25, Issue:9

    Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Celecoxib; Colon; Colonic Polyps; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Deoxycholic Acid; Dextran Sulfate; Drug Therapy, Combination; Heparin, Low-Molecular-Weight; Inflammation; Male; Mice, Inbred ICR; Neovascularization, Pathologic; Pyrazoles; Sulfonamides; Tumor Burden

2014
[Chemo-preventive effect of Angelica sinensis' supercritical extracts on AOM/DSS-induced mouse colorectal carcinoma associated with inflammation].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:7

    Topics: Angelica sinensis; Animals; Azoxymethane; Colonic Neoplasms; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Male; Mice; Mice, Inbred BALB C; Proliferating Cell Nuclear Antigen

2014
[Inflammation promotes the development of colitis-associated colorectal cancer].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2014, Volume: 17, Issue:7

    Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Immunohistochemistry; Inflammation; Interleukin-6; Mice; Mice, Inbred C57BL; Signal Transduction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha

2014
Role of inflammation and inflammatory mediators in colorectal cancer.
    Transactions of the American Clinical and Climatological Association, 2014, Volume: 125

    Topics: Adenoma; Animals; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Genes, APC; Humans; Inflammation Mediators; Intestinal Mucosa; Mice, Inbred BALB C; Mice, Knockout; Rats; Receptors, Interleukin-8B

2014
Activation of the mTORC1 and STAT3 pathways promotes the malignant transformation of colitis in mice.
    Oncology reports, 2014, Volume: 32, Issue:5

    Topics: Animals; Antineoplastic Agents; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred C57BL; Multiprotein Complexes; Signal Transduction; Sirolimus; STAT3 Transcription Factor; TOR Serine-Threonine Kinases

2014
Chemopreventive efficacy of Andrographis paniculata on azoxymethane-induced aberrant colon crypt foci in vivo.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Aberrant Crypt Foci; Andrographis; Animals; Anticarcinogenic Agents; Antioxidants; Azoxymethane; beta Catenin; Cell Line, Tumor; Colon; Colorectal Neoplasms; Female; Flavonoids; Humans; Malondialdehyde; Nitric Oxide; Phenol; Plant Extracts; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tissue Distribution

2014
Impact of the Mdm2(SNP309-G) allele on a murine model of colorectal cancer.
    Oncogene, 2015, Aug-13, Volume: 34, Issue:33

    Topics: Alleles; Animals; Apoptosis; Azoxymethane; Colorectal Neoplasms; Genetic Predisposition to Disease; Genotype; Mice; Mice, Inbred C57BL; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-mdm2; Risk; Transcription, Genetic; Tumor Suppressor Protein p53

2015
Induction of colorectal cancer in mice and histomorphometric evaluation of tumors.
    Methods in molecular biology (Clifton, N.J.), 2015, Volume: 1267

    Topics: Animals; Azoxymethane; Colorectal Neoplasms; Disease Models, Animal; Eosine Yellowish-(YS); Hematoxylin; Humans; Immunohistochemistry; Mice; Receptors, Platelet-Derived Growth Factor; S100 Calcium-Binding Protein A4; S100 Proteins; Software; Staining and Labeling; Sulfates; Tumor Burden

2015
Dietary aloe vera gel powder and extract inhibit azoxymethane- induced colorectal aberrant crypt foci in mice fed a high- fat diet.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:2

    Topics: Aberrant Crypt Foci; Aloe; Animals; Azoxymethane; Blotting, Western; Carcinogens; Colorectal Neoplasms; Cytochrome P-450 CYP2E1; Diet, High-Fat; Glutathione Transferase; Humans; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Powders; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2015
Oral concentrated grape juice suppresses expression of NF-kappa B, TNF-α and iNOS in experimentally induced colorectal carcinogenesis in Wistar rats.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:3

    Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Carcinogens; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Gene Expression Regulation, Neoplastic; Humans; Male; NF-kappa B; Phytotherapy; Plant Extracts; Precancerous Conditions; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vitis

2015
Strawberry phytochemicals inhibit azoxymethane/dextran sodium sulfate-induced colorectal carcinogenesis in Crj: CD-1 mice.
    Nutrients, 2015, Mar-10, Volume: 7, Issue:3

    Topics: Adenocarcinoma; Adenoma; Animals; Anthocyanins; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Ellagic Acid; Flavonols; Fragaria; Fruit; Functional Food; Inflammation Mediators; Male; Mice, Inbred ICR; Phytochemicals; Phytotherapy

2015
Registered report: Intestinal inflammation targets cancer-inducing activity of the microbiota.
    eLife, 2015, Mar-17, Volume: 4

    Topics: Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Escherichia coli; Genomic Islands; Interleukin-10; Intestines; Metagenome; Mice, Knockout; Microbiota; Mutation; Polyketide Synthases; Sequence Deletion; Virulence

2015
SPINK1 Status in Colorectal Cancer, Impact on Proliferation, and Role in Colitis-Associated Cancer.
    Molecular cancer research : MCR, 2015, Volume: 13, Issue:7

    Topics: Aged; Animals; Azoxymethane; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Colitis; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Glycoproteins; Humans; Inflammation; Japan; Male; Mice, Inbred C57BL; Middle Aged; Prostatic Secretory Proteins; Trypsin Inhibitor, Kazal Pancreatic

2015
Mesenchymal stem cells-regulated Treg cells suppress colitis-associated colorectal cancer.
    Stem cell research & therapy, 2015, Apr-13, Volume: 6

    Topics: Animals; Azoxymethane; CD4 Lymphocyte Count; Cell Differentiation; Cell Line; Cell Movement; Cell- and Tissue-Based Therapy; Colitis; Colon; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Humans; Inflammation; Jurkat Cells; Lymphocyte Activation; Lymphocyte Count; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Signal Transduction; Smad2 Protein; T-Lymphocytes, Regulatory; Th17 Cells; Th2 Cells; Umbilical Cord

2015
Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration.
    BMC complementary and alternative medicine, 2015, Apr-22, Volume: 15

    Topics: Animals; Azoxymethane; beta Catenin; Cadherins; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Down-Regulation; Drugs, Chinese Herbal; Epithelial-Mesenchymal Transition; Fibronectins; Humans; Male; Mice, Inbred C57BL; Myeloid Cells; Phytotherapy; Proliferating Cell Nuclear Antigen; Transforming Growth Factor beta1; Vimentin

2015
Smad2/3 linker phosphorylation is a possible marker of cancer stem cells and correlates with carcinogenesis in a mouse model of colitis-associated colorectal cancer.
    Journal of Crohn's & colitis, 2015, Volume: 9, Issue:7

    Topics: Animals; Azoxymethane; beta Catenin; Biomarkers, Tumor; Carcinogenesis; Colitis; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Ki-67 Antigen; Male; Mice; Neoplastic Stem Cells; Phosphorylation; Proto-Oncogene Proteins c-myc; Serine; Signal Transduction; Smad2 Protein; Smad3 Protein; SOX9 Transcription Factor

2015
IL-32α suppresses colorectal cancer development via TNFR1-mediated death signaling.
    Oncotarget, 2015, Apr-20, Volume: 6, Issue:11

    Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; Enzyme Activation; Humans; Inflammation; Interleukins; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Transgenic; Neoplasm Proteins; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins; Signal Transduction

2015
Trivalent Chromium has no Effect on Delaying Azoxymethane-Induced Colorectal Cancer in FVB/NJ Mice.
    Biological trace element research, 2015, Volume: 168, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Carcinogens; Chromium Compounds; Colorectal Neoplasms; Female; Insulin Resistance; Male; Mice; Mice, Inbred Strains

2015
Inhibition of Azoxymethane-induced Colorectal Aberrant Crypt Foci in Mice Fed a High-fat Diet by Pleurotus eryngii (Eringi) and Hypsizygus marmoreus (Bunashimeji).
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:9

    Topics: Aberrant Crypt Foci; Agaricales; Animals; Azoxymethane; Body Weight; Carcinogens; Cholesterol; Colorectal Neoplasms; Diet, High-Fat; Immunoenzyme Techniques; Male; Mice; Mice, Inbred C57BL; Powders; Triglycerides

2015
A critical role for cellular inhibitor of protein 2 (cIAP2) in colitis-associated colorectal cancer and intestinal homeostasis mediated by the inflammasome and survival pathways.
    Mucosal immunology, 2016, Volume: 9, Issue:1

    Topics: Animals; Azoxymethane; Baculoviral IAP Repeat-Containing 3 Protein; Cell Death; Cell Survival; Colitis; Colon; Colorectal Neoplasms; Gene Expression Regulation; Humans; Inflammasomes; Inhibitor of Apoptosis Proteins; Interleukin-18; Male; Mice; Mice, Knockout; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction; Sodium Dodecyl Sulfate; Ubiquitin-Protein Ligases

2016
Activation of AMPK by chitosan oligosaccharide in intestinal epithelial cells: Mechanism of action and potential applications in intestinal disorders.
    Biochemical pharmacology, 2015, Aug-01, Volume: 96, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Azoxymethane; beta Catenin; Calcium; Caspase 3; Cell Line, Tumor; Chitosan; Cholera Toxin; Colitis; Colorectal Neoplasms; Dextran Sulfate; Epithelial Cells; Gastrointestinal Agents; Gene Expression Regulation; Humans; Inositol 1,4,5-Trisphosphate Receptors; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Receptors, Calcium-Sensing; Receptors, G-Protein-Coupled; Signal Transduction; Type C Phospholipases

2015
St. John's Wort Attenuates Colorectal Carcinogenesis in Mice through Suppression of Inflammatory Signaling.
    Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; Diet; Dietary Supplements; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Hypericum; Inflammation; Male; Mice; NF-kappa B; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Plant Extracts; Signal Transduction

2015
Ghrelin administration suppresses inflammation-associated colorectal carcinogenesis in mice.
    Cancer science, 2015, Volume: 106, Issue:9

    Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Ghrelin; Inflammation; Male; Mice; Mice, Inbred C57BL

2015
Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer.
    Cell, 2015, Jul-02, Volume: 162, Issue:1

    Topics: Animals; Azoxymethane; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; DNA-Binding Proteins; Enterocytes; Gastrointestinal Tract; Inflammasomes; Mice; Mutation; Stem Cells

2015
The MUTYH base excision repair gene protects against inflammation-associated colorectal carcinogenesis.
    Oncotarget, 2015, Aug-14, Volume: 6, Issue:23

    Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Bone Marrow Cells; CD8-Positive T-Lymphocytes; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; DNA Glycosylases; Forkhead Transcription Factors; Guanine; Inflammation Mediators; Mice, Knockout; T-Lymphocytes, Regulatory; Time Factors

2015
Water extract of brewers' rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/β-catenin downstream signaling pathway in brewers' rice-treated rats with azoxymethane-induced colon carc
    BMC complementary and alternative medicine, 2015, Jun-30, Volume: 15

    Topics: Animals; Azoxymethane; Caspase 3; Caspase 8; Colorectal Neoplasms; HT29 Cells; Humans; Oryza; Plant Extracts; Rats; Wnt Signaling Pathway

2015
Chemoprevention of Colonic Aberrant Crypt Foci by Novel Schiff Based Dichlorido(4-Methoxy-2-{[2-(Piperazin-4-Ium-1-Yl)Ethyl]Iminomethyl}Phenolate)Cd Complex in Azoxymethane-Induced Colorectal Cancer in Rats.
    Scientific reports, 2015, Jul-23, Volume: 5

    Topics: Aberrant Crypt Foci; Animals; Antineoplastic Agents; Azoxymethane; Carcinogenesis; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Male; Rats; Rats, Sprague-Dawley; Schiff Bases; Treatment Outcome

2015
The Role of Curcumin in Modulating Colonic Microbiota During Colitis and Colon Cancer Prevention.
    Inflammatory bowel diseases, 2015, Volume: 21, Issue:11

    Topics: Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Curcumin; Dietary Supplements; Disease Models, Animal; Immunity, Mucosal; Intestinal Mucosa; Mice; Mice, 129 Strain; Mice, Knockout; Microbiota

2015
Dietary cocoa inhibits colitis associated cancer: a crucial involvement of the IL-6/STAT3 pathway.
    The Journal of nutritional biochemistry, 2015, Volume: 26, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Azoxymethane; bcl-2-Associated X Protein; bcl-X Protein; Cacao; Caspase 3; Colitis; Colorectal Neoplasms; Dextran Sulfate; Diet; Epithelial Cells; Female; Gene Expression Regulation; Inflammatory Bowel Diseases; Interleukin-6; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Neoplasms; Peroxidase; Polyphenols; Signal Transduction; STAT3 Transcription Factor

2015
Detection of Early Murine Colorectal Cancer by MMP-2/-9-Guided Fluorescence Endoscopy.
    Inflammatory bowel diseases, 2016, Volume: 22, Issue:1

    Topics: Animals; Azoxymethane; Blotting, Western; Carbocyanines; Carcinogens; Colorectal Neoplasms; Dextran Sulfate; Endoscopy, Gastrointestinal; Female; Immunoenzyme Techniques; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Optical Imaging

2016
Thrombospondin-1 in a Murine Model of Colorectal Carcinogenesis.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Immunohistochemistry; Inflammation; Mice, Inbred C57BL; Microvessels; Reproducibility of Results; RNA, Messenger; Thrombospondin 1; Up-Regulation

2015
Chemopreventive effect of oleuropein in colitis-associated colorectal cancer in c57bl/6 mice.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Cell Proliferation; Colitis; Colon; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Female; Iridoid Glucosides; Iridoids; Mice, Inbred C57BL; Neoplasms, Experimental; Th17 Cells

2016
Dietary Ziziphus jujuba Fruit Influence on Aberrant Crypt Formation and Blood Cells in Colitis-Associated Colorectal Cancer in Mice.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:17

    Topics: Aberrant Crypt Foci; Adenocarcinoma; Animals; Azoxymethane; Carcinogenesis; Chemoprevention; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Diet; Dietary Supplements; Disease Progression; Hyperplasia; Leukocyte Count; Leukocytes; Male; Mice; Mice, Inbred C57BL; Plant Preparations; Ziziphus

2015
Colon Cancer Chemoprevention by Sage Tea Drinking: Decreased DNA Damage and Cell Proliferation.
    Phytotherapy research : PTR, 2016, Volume: 30, Issue:2

    Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Cell Proliferation; Chemoprevention; Colorectal Neoplasms; Cytochrome P-450 CYP2E1; DNA Damage; Female; Plant Extracts; Rats; Rats, Inbred F344; Salvia officinalis; Teas, Herbal

2016
Suggestive evidence for the induction of colonic aberrant crypts in mice fed sodium nitrite.
    Nutrition and cancer, 2016, Volume: 68, Issue:1

    Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Colorectal Neoplasms; Female; Hemin; Mice; Sodium Nitrite

2016
Suppression of colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway by balsalazide and VSL#3.
    Journal of gastroenterology and hepatology, 2016, Volume: 31, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Azoxymethane; bcl-2-Associated X Protein; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Agents; Inflammation Mediators; Interleukin-6; Macrophages; Male; Mesalamine; Mice, Inbred C57BL; Phenylhydrazines; Phosphorylation; Probiotics; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; STAT3 Transcription Factor; Time Factors

2016
Rh2E2, a novel metabolic suppressor, specifically inhibits energy-based metabolism of tumor cells.
    Oncotarget, 2016, Mar-01, Volume: 7, Issue:9

    Topics: Animals; Apoptosis; Azoxymethane; Carcinoma, Lewis Lung; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dextran Sulfate; Drugs, Chinese Herbal; Energy Metabolism; Ginsenosides; Humans; Immunoblotting; Mice, Inbred C57BL; Mitochondrial Proteins; Molecular Structure; Neoplasms; Proteomics; S Phase Cell Cycle Checkpoints

2016
Brewers' rice attenuated aberrant crypt foci developing in colon of azoxymethane-treated rats.
    Pakistan journal of pharmaceutical sciences, 2016, Volume: 29, Issue:1

    Topics: Aberrant Crypt Foci; Alanine Transaminase; Animals; Azoxymethane; Body Weight; Colorectal Neoplasms; Male; Oryza; Oxidative Stress; Rats; Rats, Sprague-Dawley

2016
PDCD4 Deficiency Aggravated Colitis and Colitis-associated Colorectal Cancer Via Promoting IL-6/STAT3 Pathway in Mice.
    Inflammatory bowel diseases, 2016, Volume: 22, Issue:5

    Topics: Animals; Apoptosis Regulatory Proteins; Azoxymethane; Blotting, Western; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cytokines; Female; Immunoenzyme Techniques; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Real-Time Polymerase Chain Reaction; RNA-Binding Proteins; Signal Transduction; STAT3 Transcription Factor

2016
Dietary cholesterol promotes AOM-induced colorectal cancer through activating the NLRP3 inflammasome.
    Biochemical pharmacology, 2016, Apr-01, Volume: 105

    Topics: Animals; Azoxymethane; Carrier Proteins; Cell Line; Cholesterol, Dietary; Colorectal Neoplasms; Humans; Inflammasomes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species

2016
Paricalcitol Enhances the Chemopreventive Efficacy of 5-Fluorouracil on an Intermediate-Term Model of Azoxymethane-Induced Colorectal Tumors in Rats.
    Cancer prevention research (Philadelphia, Pa.), 2016, Volume: 9, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azoxymethane; Blotting, Western; Carcinogens; Colorectal Neoplasms; Disease Models, Animal; Ergocalciferols; Fluorouracil; Immunohistochemistry; Male; Polymerase Chain Reaction; Rats; Rats, Wistar; Transcriptome

2016
MicroRNA-17~92 inhibits colorectal cancer progression by targeting angiogenesis.
    Cancer letters, 2016, 07-01, Volume: 376, Issue:2

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Progression; Gene Expression Regulation, Neoplastic; HCT116 Cells; Heterografts; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice, Nude; Mice, Transgenic; MicroRNAs; Neoplasm Transplantation; Neovascularization, Pathologic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Long Noncoding; Time Factors; Vascular Endothelial Growth Factor A

2016
AOM/DSS Model of Colitis-Associated Cancer.
    Methods in molecular biology (Clifton, N.J.), 2016, Volume: 1422

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Mice

2016
Decreased Expression of Retinoid X Receptors During Human and Azoxymethane-induced Colorectal Carcinogenesis in the Rat.
    Anticancer research, 2016, Volume: 36, Issue:6

    Topics: Animals; Azoxymethane; Colorectal Neoplasms; Humans; Intestinal Mucosa; Rats; Rats, Inbred F344; Retinoid X Receptors

2016
Hypocholesterolemic and Anticarcinogenic Effect of Vicia faba Protein Hydrolyzates.
    Nutrition and cancer, 2016, Volume: 68, Issue:5

    Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Antioxidants; Azoxymethane; Cholesterol, Dietary; Colorectal Neoplasms; Diet; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; Plant Extracts; Protein Hydrolysates; Vicia faba

2016
The Aryl Hydrocarbon Receptor is a Repressor of Inflammation-associated Colorectal Tumorigenesis in Mouse.
    Annals of surgery, 2016, Volume: 264, Issue:3

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; DNA Damage; Gene Expression; Indoles; Mice; Mice, Inbred C57BL; Receptors, Aryl Hydrocarbon; RNA

2016
Chemopreventive effect of Phaleria macrocarpa on colorectal cancer aberrant crypt foci in vivo.
    Journal of ethnopharmacology, 2016, Dec-04, Volume: 193

    Topics: Animals; Antioxidants; Azoxymethane; bcl-2-Associated X Protein; Body Weight; Carcinogens; Colorectal Neoplasms; Female; HT29 Cells; Humans; Male; Plant Extracts; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Thymelaeaceae

2016
G-protein-coupled receptors mediate ω-3 PUFAs-inhibited colorectal cancer by activating the Hippo pathway.
    Oncotarget, 2016, Sep-06, Volume: 7, Issue:36

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cytoplasm; Dextran Sulfate; Fatty Acids, Omega-3; Hippo Signaling Pathway; HT29 Cells; Humans; Mice; Mice, Inbred BALB C; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Transport; Receptors, G-Protein-Coupled; YAP-Signaling Proteins

2016
Unpolished Thai Rice Prevents Aberrant Crypt Foci Formation through the Invovement of ?catenin and COX2 Expression in AzoxymethaneTreated Rats.
    Asian Pacific journal of cancer prevention : APJCP, 2016, Volume: 17, Issue:7

    Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Biomarkers; Catenins; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase 2; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-6; Male; Oryza; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Thailand

2016
Chemopreventive Properties and Toxicity of Kelulut Honey in Sprague Dawley Rats Induced with Azoxymethane.
    BioMed research international, 2016, Volume: 2016

    Topics: Animals; Azoxymethane; Carcinogens; Chemoprevention; Colorectal Neoplasms; Honey; Male; Rats; Rats, Sprague-Dawley; Treatment Outcome

2016
Protective effects of Huangqin Decoction against ulcerative colitis and associated cancer in mice.
    Oncotarget, 2016, Sep-20, Volume: 7, Issue:38

    Topics: Animals; Antioxidants; Azoxymethane; Chromatography, High Pressure Liquid; Colitis, Ulcerative; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Drugs, Chinese Herbal; Flavanones; Inflammation; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Oxidative Stress; Plant Extracts; Scutellaria baicalensis

2016
TNIK inhibition abrogates colorectal cancer stemness.
    Nature communications, 2016, 08-26, Volume: 7

    Topics: Adenomatous Polyposis Coli Protein; Administration, Oral; Aged; Animals; Azoxymethane; beta Catenin; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; Crystallography, X-Ray; Female; Germinal Center Kinases; Humans; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Middle Aged; Mutation; Neoplastic Stem Cells; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Quinazolines; Recombinant Proteins; Ubiquitin-Protein Ligases; Wnt Proteins; Wnt Signaling Pathway; Xenograft Model Antitumor Assays

2016
Murine MTHFD1-synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors.
    Molecular carcinogenesis, 2017, Volume: 56, Issue:3

    Topics: Aminohydrolases; Animals; Azoxymethane; Cell Proliferation; Cells, Cultured; Colorectal Neoplasms; Dextran Sulfate; Female; Formate-Tetrahydrofolate Ligase; Gene Expression Regulation, Neoplastic; Humans; Male; Methenyltetrahydrofolate Cyclohydrolase; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Minor Histocompatibility Antigens; Multienzyme Complexes; Multifunctional Enzymes; Polymorphism, Single Nucleotide

2017
Prevention of azoxymethane/dextran sodium sulfate-induced mouse colon carcinogenesis by processed Aloe vera gel.
    International immunopharmacology, 2016, Volume: 40

    Topics: Adenocarcinoma; Aloe; Animals; Azoxymethane; Carcinogenesis; CDX2 Transcription Factor; Cell Cycle; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gels; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; NF-kappa B; Plant Extracts; Tumor Suppressor Proteins

2016
A role for the vitamin D pathway in non-intestinal lesions in genetic and carcinogen models of colorectal cancer and in familial adenomatous polyposis.
    Oncotarget, 2016, Dec-06, Volume: 7, Issue:49

    Topics: Adenocarcinoma; Adenomatous Polyposis Coli; Animals; Azoxymethane; beta Catenin; Cell Transformation, Neoplastic; Colorectal Neoplasms; Disease Models, Animal; Disease Progression; Gardner Syndrome; Genes, APC; Genetic Predisposition to Disease; Mice, Inbred C57BL; Mice, Knockout; Mutation; Phenotype; Polymorphism, Single Nucleotide; Receptors, Calcitriol; Risk Factors; Time Factors; Vitamin D; Wnt Signaling Pathway

2016
Anti-inflammatory natural product goniothalamin reduces colitis-associated and sporadic colorectal tumorigenesis.
    Carcinogenesis, 2017, Volume: 38, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Azoxymethane; Biological Products; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Inflammation; Inflammation Mediators; Macrophages; Mice; Mice, Inbred C57BL; Pyrones

2017
Açaí Berries Inhibit Colon Tumorigenesis in Azoxymethane/Dextran Sulfate Sodium-Treated Mice.
    Gut and liver, 2017, Mar-15, Volume: 11, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Carcinogens; Colon; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Down-Regulation; Euterpe; Genes, bcl-2; Male; Mice; Peroxidase; Phytotherapy; Powders; Proliferating Cell Nuclear Antigen

2017
RNA virus receptor Rig-I monitors gut microbiota and inhibits colitis-associated colorectal cancer.
    Journal of experimental & clinical cancer research : CR, 2017, 01-05, Volume: 36, Issue:1

    Topics: Animals; Azoxymethane; Bacteria; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; DNA, Bacterial; Down-Regulation; Gastrointestinal Microbiome; Humans; Immunoglobulin A; Interleukin-6; Membrane Proteins; Mice; Nerve Tissue Proteins; Pancreatitis-Associated Proteins; Phosphorylation; Phylogeny; Receptors, Cell Surface; Receptors, Retinoic Acid; Sequence Analysis, DNA; STAT3 Transcription Factor

2017
Genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer.
    Scientific reports, 2017, Volume: 7, Issue:1

    Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Exome Sequencing; Genetic Variation; Humans; Male; Mice, Inbred C57BL; Mutation; Neoplasms, Experimental

2017
MicroRNA 301A Promotes Intestinal Inflammation and Colitis-Associated Cancer Development by Inhibiting BTG1.
    Gastroenterology, 2017, Volume: 152, Issue:6

    Topics: Aged; Animals; Azoxymethane; Cadherins; Case-Control Studies; Cell Proliferation; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Down-Regulation; Epithelial Cells; Female; Gene Expression; HCT116 Cells; Humans; Inflammatory Breast Neoplasms; Interleukin-1beta; Intestinal Mucosa; JNK Mitogen-Activated Protein Kinases; Male; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Middle Aged; Neoplasm Proteins; Neoplasm Transplantation; RNA, Messenger; Signal Transduction; Transcription Factor RelA; Transfection; Tumor Burden; Up-Regulation

2017
Suppression of colorectal oncogenesis by selenium-enriched milk proteins: apoptosis and K-ras mutations.
    Cancer research, 2008, Jun-15, Volume: 68, Issue:12

    Topics: Animals; Apoptosis; Azoxymethane; Carcinogens; Cell Proliferation; Colorectal Neoplasms; Diet; DNA Damage; Dose-Response Relationship, Drug; Genes, ras; Glutathione Peroxidase; Male; Mice; Mice, Inbred C57BL; Milk Proteins; Mutation; Selenium; Yeasts

2008
Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition.
    Gut, 2008, Volume: 57, Issue:11

    Topics: Adiponectin; AMP-Activated Protein Kinase Kinases; Animals; Apoptosis; Azoxymethane; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Polyps; Colorectal Neoplasms; Dietary Fats; Intestinal Mucosa; Mice; Mice, Knockout; Obesity; Precancerous Conditions; Protein Biosynthesis; Protein Kinases; Receptors, Adiponectin; TOR Serine-Threonine Kinases

2008
Polyethylene glycol-mediated colorectal cancer chemoprevention: roles of epidermal growth factor receptor and Snail.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:9

    Topics: Animals; Azoxymethane; Cell Proliferation; Chemoprevention; Colorectal Neoplasms; Down-Regulation; Epithelial Cells; ErbB Receptors; Gefitinib; HT29 Cells; Humans; Intestinal Mucosa; Lysosomes; Male; Models, Biological; Polyethylene Glycols; Quinazolines; Rats; Rats, Inbred F344; Repressor Proteins; Snail Family Transcription Factors; Transcription Factors; Transcription, Genetic

2008
Adiponectin deficiency enhances colorectal carcinogenesis and liver tumor formation induced by azoxymethane in mice.
    World journal of gastroenterology, 2008, Nov-14, Volume: 14, Issue:42

    Topics: Adiponectin; Animals; Azoxymethane; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Disease Models, Animal; Liver Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Proliferating Cell Nuclear Antigen; Time Factors; Up-Regulation

2008
Increased susceptibility of Nrf2 knockout mice to colitis-associated colorectal cancer.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:3

    Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Cytoprotection; Dextran Sulfate; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2

2008
Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon.
    International journal of cancer, 2009, Sep-01, Volume: 125, Issue:5

    Topics: Animals; Apoptosis; Aurora Kinase B; Aurora Kinases; Azoxymethane; Blotting, Western; Cannabinoid Receptor Antagonists; Cell Cycle; Cell Proliferation; Checkpoint Kinase 1; Chromosome Aberrations; Colony-Forming Units Assay; Colorectal Neoplasms; Cyclin B; Cyclin B1; DNA Damage; Female; Humans; Mice; Mice, Inbred C57BL; Mitotic Index; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Polyploidy; Precancerous Conditions; Protein Kinases; Protein Serine-Threonine Kinases; Pyrazoles; Rimonabant; Tumor Cells, Cultured

2009
Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.
    Journal of gastroenterology, 2009, Volume: 44, Issue:9

    Topics: Animals; Antineoplastic Agents; Azoxymethane; Benzamides; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Drug Delivery Systems; Drug Screening Assays, Antitumor; I-kappa B Kinase; Macrophages; Male; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; NF-kappa B; Peptides

2009
Involvement of JNK pathway in the promotion of the early stage of colorectal carcinogenesis under high-fat dietary conditions.
    Gut, 2009, Volume: 58, Issue:12

    Topics: Animals; Azoxymethane; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; Dietary Fats; Disease Models, Animal; Humans; Insulin; Insulin Resistance; Intestinal Mucosa; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Signal Transduction

2009
Cyclophilin C-associated protein (CyCAP) knock-out mice spontaneously develop colonic mucosal hyperplasia and exaggerated tumorigenesis after treatment with carcinogen azoxymethane.
    BMC cancer, 2009, Jul-24, Volume: 9

    Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Cell Proliferation; Colon; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Glycoproteins; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Mice, Knockout

2009
Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice.
    The Journal of clinical investigation, 2009, Volume: 119, Issue:9

    Topics: Animals; Apoptosis; Azoxymethane; Cell Proliferation; Colon; Colorectal Neoplasms; Gastrins; Gene Expression; Humans; Hyaluronan Receptors; Mice; Mice, Knockout; Mice, Transgenic; Protein Precursors; Receptor, Cholecystokinin B; Recombinant Proteins

2009
Inhibition of azoxymethane-induced colorectal cancer by CP-31398, a TP53 modulator, alone or in combination with low doses of celecoxib in male F344 rats.
    Cancer research, 2009, Oct-15, Volume: 69, Issue:20

    Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Blotting, Western; Carcinogens; Celecoxib; Cell Proliferation; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Drug Therapy, Combination; Immunoenzyme Techniques; In Situ Nick-End Labeling; Male; Maximum Tolerated Dose; Membrane Proteins; Pyrazoles; Pyrimidines; Rats; Rats, Inbred F344; Sulfonamides; Tumor Suppressor Protein p53

2009
Differential in vivo mechanism of chemoprevention of tumor formation in azoxymethane/dextran sodium sulfate mice by PEITC and DBM.
    Carcinogenesis, 2010, Volume: 31, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Body Weight; Cell Cycle; Chalcones; Colorectal Neoplasms; Dextran Sulfate; Intestinal Mucosa; Intestinal Polyps; Isothiocyanates; Male; Mice; Mice, Inbred C57BL

2010
Phosphatidylinositol 3-kinase gamma inhibition ameliorates inflammation and tumor growth in a model of colitis-associated cancer.
    Gastroenterology, 2010, Volume: 138, Issue:4

    Topics: Animals; Azoxymethane; CD4-Positive T-Lymphocytes; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Immunity, Innate; Inflammatory Bowel Diseases; Mice; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors

2010
Ibadronate may prevent colorectal carcinogenesis in mice with ulcerative colitis.
    Anticancer research, 2009, Volume: 29, Issue:11

    Topics: Animals; Azoxymethane; Carcinogens; Colitis, Ulcerative; Colorectal Neoplasms; Dextran Sulfate; Diphosphonates; Female; Mice; Mice, Inbred CBA; RNA, Messenger; Thymidine Kinase; Thymidylate Synthase

2009
Inhibition of experimental colorectal cancer and reduction in renal and gastrointestinal toxicities by copper-indomethacin in rats.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:4

    Topics: Acetylglucosaminidase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Carcinogens; Cecum; Cell Line, Tumor; Colon; Colorectal Neoplasms; Copper; DNA, Mitochondrial; Drug Combinations; Duodenal Ulcer; Electrolytes; Gastric Mucosa; Gastrointestinal Diseases; Haptoglobins; Hemoglobins; Indomethacin; Intestinal Mucosa; Kidney Diseases; Male; Permeability; Rats; Rats, Sprague-Dawley; Stomach Ulcer

2010
Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Feb-09, Volume: 107, Issue:6

    Topics: Animals; Azoxymethane; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Female; HCT116 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mutation; Neoplasms, Experimental; Paxillin; Phosphorylation; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Substrate Specificity; Transfection; Transplantation, Heterologous; Tyrosine

2010
Enhanced acute apoptotic response to azoxymethane-induced DNA damage in the rodent colonic epithelium by Tyrian purple precursors: a potential colorectal cancer chemopreventative.
    Cancer biology & therapy, 2010, Mar-01, Volume: 9, Issue:5

    Topics: Animals; Azoxymethane; Carcinogens; Colon; Colorectal Neoplasms; DNA Damage; Epithelium; Female; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Proliferating Cell Nuclear Antigen; Random Allocation; Rodentia

2010
CCL2 (pM levels) as a therapeutic agent in Inflammatory Bowel Disease models in mice.
    Inflammatory bowel diseases, 2010, Volume: 16, Issue:9

    Topics: Animals; Azoxymethane; Blotting, Western; Carcinogens; Cell Adhesion; Cell Movement; Cell Proliferation; Chemokine CCL2; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunoenzyme Techniques; Inflammatory Bowel Diseases; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Trinitrobenzenesulfonic Acid

2010
Optimization of visibility and quantification of aberrant crypt foci in colonic mucosa in Wistar rats.
    Acta cirurgica brasileira, 2010, Volume: 25, Issue:2

    Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Intestinal Mucosa; Microscopy; Rats; Rats, Wistar

2010
R-flurbiprofen suppresses distal nonmucin-producing colorectal tumors in azoxymethane-treated rats, without suppressing eicosanoid production.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:6

    Topics: Animals; Antineoplastic Agents; Azoxymethane; Carcinogens; Colorectal Neoplasms; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Eicosanoids; Flurbiprofen; Male; Mucins; Rats; Rats, Sprague-Dawley; Sulindac

2010
Sex modulates intestinal transformation by the tumor-suppressor GCC.
    Clinical and translational science, 2008, Volume: 1, Issue:2

    Topics: Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; Enterocytes; Female; Guanylate Cyclase; Intestines; Male; Mice; Receptors, Enterotoxin; Receptors, Guanylate Cyclase-Coupled; Receptors, Peptide; Sex Characteristics; Tumor Suppressor Proteins

2008
Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by activating AMP-activated protein kinase.
    Molecular carcinogenesis, 2010, Volume: 49, Issue:7

    Topics: AMP-Activated Protein Kinases; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cell Proliferation; Colon; Colonic Polyps; Colorectal Neoplasms; Epithelial Cells; Hypoglycemic Agents; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Lipids; Metformin; Mice; Mice, Inbred BALB C; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; TOR Serine-Threonine Kinases

2010
Dietary-feeding of grape seed extract prevents azoxymethane-induced colonic aberrant crypt foci formation in fischer 344 rats.
    Molecular carcinogenesis, 2010, Volume: 49, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; beta Catenin; Cell Proliferation; Colon; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 2; Gene Expression Regulation, Neoplastic; Grape Seed Extract; Microtubule-Associated Proteins; NF-kappa B; Nitric Oxide Synthase Type II; Rats; Rats, Inbred F344; Survivin

2010
2,3',4,4',5'-Pentamethoxy-trans-stilbene, a resveratrol derivative, inhibits colitis-associated colorectal carcinogenesis in mice.
    British journal of pharmacology, 2010, Volume: 160, Issue:6

    Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Cell Line, Tumor; Cell Proliferation; Colitis; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred BALB C; Stilbenes

2010
High susceptibility to azoxymethane-induced colorectal carcinogenesis in obese KK-Ay mice.
    International journal of cancer, 2011, Aug-01, Volume: 129, Issue:3

    Topics: Aberrant Crypt Foci; Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Disease Models, Animal; Disease Susceptibility; Incidence; Mice; Mice, Inbred C57BL; Mice, Obese; Receptors, Leptin

2011
A two-locus system controls susceptibility to colitis-associated colon cancer in mice.
    Oncotarget, 2010, Volume: 1, Issue:6

    Topics: Animals; Azoxymethane; Carcinogens; Chromosome Mapping; Chromosomes, Mammalian; Colitis; Colorectal Neoplasms; Crosses, Genetic; Disease Models, Animal; Female; Genetic Linkage; Genetic Loci; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Quantitative Trait Loci

2010
Dietary acrylamide does not increase colon aberrant crypt foci formation in male F344 rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:6

    Topics: Aberrant Crypt Foci; Acrylamide; Animals; Azoxymethane; Biomarkers, Tumor; Carcinogens; Caspase 9; Colon; Colorectal Neoplasms; Corn Oil; Drug Interactions; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344

2011
The Wnt antagonist Dkk1 regulates intestinal epithelial homeostasis and wound repair.
    Gastroenterology, 2011, Volume: 141, Issue:1

    Topics: Acute Disease; Animals; Antibodies, Monoclonal; Azoxymethane; beta Catenin; Cell Proliferation; Cells, Cultured; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Homeostasis; Injections, Intraperitoneal; Intercellular Signaling Peptides and Proteins; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Transgenic; Signal Transduction; Time Factors; Wnt Proteins; Wound Healing

2011
Effect of maternal and postweaning folic acid supplementation on colorectal cancer risk in the offspring.
    Gut, 2011, Volume: 60, Issue:12

    Topics: Animals; Animals, Newborn; Apoptosis; Azoxymethane; Carcinogens; Cell Proliferation; Colorectal Neoplasms; Dietary Supplements; DNA Methylation; Female; Folic Acid; Intestinal Mucosa; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Risk Factors; Weaning

2011
Prevention of colitis-associated colorectal cancer with 8-hydroxydeoxyguanosine.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticarcinogenic Agents; Azoxymethane; Colitis; Colorectal Neoplasms; Deoxyguanosine; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation; Interleukin-10; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms; STAT3 Transcription Factor; Sulfates

2011
Characterization of chromosomal instability in murine colitis-associated colorectal cancer.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: Animals; Azoxymethane; beta Catenin; Cell Proliferation; Chromosomal Instability; Colitis; Colorectal Neoplasms; Dextran Sulfate; Endoscopy, Digestive System; Gene Expression Regulation, Neoplastic; Humans; Interferon-gamma; Interleukin-10; Ki-67 Antigen; Mice; Neoplasm Staging; Tumor Suppressor Protein p53

2011
Early lesion formation in colorectal carcinogenesis is associated with adiponectin status whereas neoplastic lesions are associated with diet and sex in C57BL/6J mice.
    Nutrition and cancer, 2011, Volume: 63, Issue:8

    Topics: Adiponectin; Animals; Azoxymethane; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; Dextran Sulfate; Diet; Disease Models, Animal; Female; Gene Expression Regulation; Genotype; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Insulin; Receptors, Adiponectin; Risk Factors; Sex Factors; Signal Transduction; Toll-Like Receptor 4

2011
Low-dose dietary resveratrol has differential effects on colorectal tumorigenesis in adiponectin knockout and wild-type mice.
    Nutrition and cancer, 2011, Volume: 63, Issue:8

    Topics: Adipocytes; Adiponectin; Animals; Azoxymethane; Caco-2 Cells; Cell Transformation, Neoplastic; Colorectal Neoplasms; Dextran Sulfate; Dietary Fats; Dose-Response Relationship, Drug; Female; Humans; Insulin; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Resveratrol; Sex Factors; Stilbenes; Weight Gain

2011
Enhancement of TGF-β signaling responses by the E3 ubiquitin ligase Arkadia provides tumor suppression in colorectal cancer.
    Cancer research, 2011, Oct-15, Volume: 71, Issue:20

    Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Azoxymethane; Base Sequence; Colon; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Mice; Molecular Sequence Data; Mutation; Nuclear Proteins; Proto-Oncogene Proteins; Severity of Illness Index; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases

2011
Chronic psychosocial stress increases the risk for inflammation-related colon carcinogenesis in male mice.
    Stress (Amsterdam, Netherlands), 2012, Volume: 15, Issue:4

    Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Housing, Animal; Inflammation; Interferon-gamma; Male; Mice; Mice, Inbred C57BL; Social Dominance; Stress, Psychological

2012
Effect of a hyperlipidic diet rich in omegas 3, 6 and 9 on aberrant crypt formation in rat colonic mucosa.
    Acta cirurgica brasileira, 2012, Volume: 27, Issue:1

    Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Body Weight; Carcinogens; Colon; Colorectal Neoplasms; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Intestinal Mucosa; Male; Random Allocation; Rats; Rats, Wistar

2012
Effect of dietary fibre of barley variety 'Rihane' on azoxymethane-induced aberrant crypt foci development and on colonic microbiota diversity in rats.
    The British journal of nutrition, 2012, Dec-14, Volume: 108, Issue:11

    Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Bifidobacterium; Carcinogens; Colon; Colorectal Neoplasms; Dietary Fiber; Disease Models, Animal; Enterobacteriaceae; Gastrointestinal Contents; Hordeum; Hydrogen-Ion Concentration; Intestinal Mucosa; Male; Phylogeny; Prebiotics; Random Allocation; Rats; Rats, Wistar; Seeds; Tunisia

2012
Advanced glycation end products (AGE) induce the receptor for AGE in the colonic mucosa of azoxymethane-injected Fischer 344 rats fed with a high-linoleic acid and high-glucose diet.
    Journal of gastroenterology, 2012, Volume: 47, Issue:10

    Topics: Animals; Azoxymethane; Body Weight; Carcinogens; Cell Culture Techniques; Colon; Colorectal Neoplasms; Diet; Enzyme-Linked Immunosorbent Assay; Glucose; Glycation End Products, Advanced; Immunoblotting; Immunohistochemistry; Intestinal Mucosa; Linoleic Acid; Male; Rats; Rats, Inbred F344; Receptor for Advanced Glycation End Products; Receptors, Immunologic

2012
Metabonomic variations associated with AOM-induced precancerous colorectal lesions and resveratrol treatment.
    Journal of proteome research, 2012, Jun-01, Volume: 11, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Colorectal Neoplasms; Male; Metabolome; Precancerous Conditions; Rats; Rats, Wistar; Resveratrol; Stilbenes

2012
Arsenic and chromium in drinking water promote tumorigenesis in a mouse colitis-associated colorectal cancer model and the potential mechanism is ROS-mediated Wnt/β-catenin signaling pathway.
    Toxicology and applied pharmacology, 2012, Jul-01, Volume: 262, Issue:1

    Topics: Animals; Antioxidants; Arsenic; Azoxymethane; Carcinogens, Environmental; Cell Line; Chromium; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Drinking Water; Electrophoresis, Gel, Two-Dimensional; Humans; Mass Spectrometry; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Water Pollutants, Chemical; Wnt Signaling Pathway

2012
DNA repair is indispensable for survival after acute inflammation.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:7

    Topics: AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase; Animals; Azoxymethane; Carcinogens; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Dioxygenases; DNA Glycosylases; DNA Repair; DNA Repair Enzymes; Epistasis, Genetic; Female; Genetic Predisposition to Disease; Kaplan-Meier Estimate; Lethal Dose 50; Lipopolysaccharides; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Pancreas; Pancreatitis

2012
Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammation.
    The Journal of experimental medicine, 2012, Jul-02, Volume: 209, Issue:7

    Topics: Animals; Azoxymethane; Carcinogens; Chromosome Mapping; Chromosomes, Mammalian; Colitis; Colorectal Neoplasms; Disease Resistance; Genetic Loci; Genetic Predisposition to Disease; Helicobacter hepaticus; Helicobacter Infections; Host-Pathogen Interactions; Humans; Immunity, Innate; Inflammation; Mice; Mice, 129 Strain; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Polymorphism, Single Nucleotide; Telomere

2012
Efficacy of EGFR inhibition is modulated by model, sex, genetic background and diet: implications for preclinical cancer prevention and therapy trials.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Animals; Antineoplastic Agents; Azoxymethane; Colorectal Neoplasms; Diet; Disease Models, Animal; ErbB Receptors; Female; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Quinazolines; Sex Factors; Tyrphostins

2012
Tomato powder impedes the development of azoxymethane-induced colorectal cancer in rats through suppression of COX-2 expression via NF-κB and regulating Nrf2/HO-1 pathway.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Signal Transduction; Solanum lycopersicum; Up-Regulation

2012
Red strain oryza sativa-unpolished thai rice prevents oxidative stress and colorectal aberrant crypt foci formation in rats.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:5

    Topics: Aberrant Crypt Foci; Animals; Antioxidants; Azoxymethane; Benzothiazoles; Biphenyl Compounds; Colorectal Neoplasms; Male; Malondialdehyde; Oryza; Oxidative Stress; Phytotherapy; Picrates; Plant Extracts; Rats; Rats, Sprague-Dawley; Sulfonic Acids; Thiazoles

2012
Intestinal inflammation targets cancer-inducing activity of the microbiota.
    Science (New York, N.Y.), 2012, Oct-05, Volume: 338, Issue:6103

    Topics: Animals; Azoxymethane; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; DNA Damage; Escherichia coli; Interleukin-10; Intestines; Metagenome; Mice; Mice, Mutant Strains; Polyketide Synthases; Sequence Deletion

2012
Metabolic profiling, a noninvasive approach for the detection of experimental colorectal neoplasia.
    Cancer prevention research (Philadelphia, Pa.), 2012, Volume: 5, Issue:12

    Topics: Animals; Azoxymethane; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Feces; Gas Chromatography-Mass Spectrometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Metabolome; Metabolomics; Mice; Models, Statistical; Neoplasms, Experimental; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors

2012
Mast cells and inflammation-associated colorectal carcinogenesis.
    Seminars in immunopathology, 2013, Volume: 35, Issue:2

    Topics: Animals; Azoxymethane; Carcinogens; Colon; Colorectal Neoplasms; Cytokines; Inflammatory Bowel Diseases; Macrophages; Male; Mast Cells; Mice; Mice, Mutant Strains; Neoplasm Proteins; Neoplasms, Experimental

2013
Suppressive effect of pioglitazone, a PPAR gamma ligand, on azoxymethane-induced colon aberrant crypt foci in KK-Ay mice.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:8

    Topics: Aberrant Crypt Foci; Adipokines; Animals; Azoxymethane; Biomarkers; Carcinogens; Colorectal Neoplasms; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Hypoglycemic Agents; Immunoenzyme Techniques; Insulin; Intra-Abdominal Fat; Leptin; Lipids; Mice; Mice, Inbred C57BL; Obesity; Pioglitazone; PPAR gamma; Thiazolidinediones

2012
Vanillin differentially affects azoxymethane-injected rat colon carcinogenesis and gene expression.
    Journal of medicinal food, 2012, Volume: 15, Issue:12

    Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Benzaldehydes; Cell Cycle; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; DNA Mismatch Repair; Gene Expression; Male; Mutation; Rats; Rats, Sprague-Dawley

2012
Characterization of PPAR dual ligand MCC-555 in AOM-induced colorectal tumorigenesis.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2013, Volume: 65, Issue:6

    Topics: Aberrant Crypt Foci; Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred Strains; Mitosis; Mucin-2; PPAR gamma; Thiazolidinediones

2013
The combination of 1alpha,25(OH2)-vitamin D3, calcium and acetylsalicylic acid affects azoxymethane-induced aberrant crypt foci and colorectal tumours in rats.
    Cancer letters, 2002, Dec-01, Volume: 186, Issue:1

    Topics: Animals; Aspirin; Azoxymethane; Body Weight; Calcitriol; Calcium; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Therapy, Combination; Eating; Male; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344

2002
Direct measure of insulin sensitivity with the hyperinsulinemic-euglycemic clamp and surrogate measures of insulin sensitivity with the oral glucose tolerance test: correlations with aberrant crypt foci promotion in rats.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2003, Volume: 12, Issue:1

    Topics: Animals; Azoxymethane; Colorectal Neoplasms; Dietary Fats; Glucose Clamp Technique; Glucose Tolerance Test; Hyperinsulinism; Insulin; Insulin Resistance; Male; Precancerous Conditions; Rats; Rats, Inbred F344

2003
Chemoprevention for colorectal tumorigenesis associated with chronic colitis in mice via apoptosis.
    Journal of experimental & clinical cancer research : CR, 2003, Volume: 22, Issue:1

    Topics: Animals; Apoptosis; Azoxymethane; Carcinogens; Chemoprevention; Chronic Disease; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Intestinal Mucosa; Male; Mice; Mice, Inbred CBA; Sulindac; Water Supply

2003
Meat and cancer: haemoglobin and haemin in a low-calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats.
    Carcinogenesis, 2003, Volume: 24, Issue:10

    Topics: Animals; Antioxidants; Azoxymethane; Butylated Hydroxyanisole; Calcium; Colon; Colorectal Neoplasms; Diet; Dose-Response Relationship, Drug; Feces; Female; Heme; Hemin; Hemoglobins; Lipid Peroxidation; Meat; Olive Oil; Plant Oils; Rats; Rats, Inbred F344; Rutin; Safflower Oil; Thiobarbituric Acid Reactive Substances; Weight Gain

2003
Dietary sodium gluconate protects rats from large bowel cancer by stimulating butyrate production.
    The Journal of nutrition, 2004, Volume: 134, Issue:4

    Topics: Adenocarcinoma; Adenoma; Animals; Apoptosis; Azoxymethane; beta Catenin; Butyrates; Carcinogens; Cecum; Colon; Colorectal Neoplasms; Cytoskeletal Proteins; Deoxycholic Acid; Diet; Gluconates; Immunohistochemistry; In Situ Nick-End Labeling; Intestines; Male; Organ Size; Rats; Rats, Inbred F344; Trans-Activators

2004
[Beta-catenin-accumulated crypt--a novel pre-cancerous condition in rat colorectal neoplasm model].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 2004, Volume: 33, Issue:3

    Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Colorectal Neoplasms; Cytoskeletal Proteins; Precancerous Conditions; Rats; Rats, Inbred F344; Trans-Activators

2004
Chemoprevention of colorectal cancer by grape seed proanthocyanidin is accompanied by a decrease in proliferation and increase in apoptosis.
    Nutrition and cancer, 2004, Volume: 49, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; Azoxymethane; Biflavonoids; Carcinogens; Caspase 3; Caspases; Catechin; Cell Division; Colorectal Neoplasms; Immunohistochemistry; Male; Proanthocyanidins; Random Allocation; Rats; Rats, Inbred F344

2004
Inhibition of azoxymethane-induced aberrant crypt foci in rat by diphenylmethyl selenocyanate through downregulation of COX-2 and modulation of glutathione-S-transferase and lipid peroxidation.
    Biological trace element research, 2005,Summer, Volume: 105, Issue:1-3

    Topics: Animals; Azoxymethane; Blotting, Western; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Lipid Peroxidation; Liver; Male; Models, Chemical; Neoplasms, Experimental; Organoselenium Compounds; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Selenium; Time Factors

2005
Suppressive effect of an inducible nitric oxide inhibitor, ONO-1714, on AOM-induced rat colon carcinogenesis.
    Nitric oxide : biology and chemistry, 2006, Volume: 14, Issue:2

    Topics: Amidines; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Heterocyclic Compounds, 2-Ring; Male; Nitric Oxide Synthase Type II; Precancerous Conditions; Rats; Rats, Inbred F344

2006
Azoxymethane is a genetic background-dependent colorectal tumor initiator and promoter in mice: effects of dose, route, and diet.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 88, Issue:2

    Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colon; Colorectal Neoplasms; Crosses, Genetic; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnancy; Research Design; Species Specificity

2005
Predisposition to colorectal cancer in rats with resolved colitis: role of cyclooxygenase-2-derived prostaglandin d2.
    The American journal of pathology, 2005, Volume: 167, Issue:5

    Topics: Animals; Azoxymethane; beta Catenin; Colitis; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Disease Susceptibility; Intramolecular Oxidoreductases; Lipocalins; Male; Prostaglandin D2; Rats; Rats, Wistar; Receptors, Immunologic; Receptors, Prostaglandin; Trinitrobenzenesulfonic Acid

2005
Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats.
    The Journal of nutrition, 2006, Volume: 136, Issue:11

    Topics: Animals; Azoxymethane; beta Catenin; Body Weight; Cell Proliferation; Colorectal Neoplasms; Dietary Supplements; Male; Precancerous Conditions; Quercetin; Rats; Rats, Inbred F344; Rutin

2006
The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer.
    Gastroenterology, 2007, Volume: 132, Issue:4

    Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Azoxymethane; Biomarkers, Tumor; Bromodeoxyuridine; Carcinogens; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin A; Cyclin A2; Cyclin B; Cyclin B1; Dextran Sulfate; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubule-Associated Proteins; Neoplasm Proteins; Neoplasms, Experimental; Polymerase Chain Reaction; Proteins; Repressor Proteins; RNA, Neoplasm; RNA, Small Interfering; RNA, Untranslated; Survivin; TCF Transcription Factors; Transcription Factor 7-Like 2 Protein

2007
Bayesian hierarchical modeling for time course microarray experiments.
    Biometrics, 2007, Volume: 63, Issue:2

    Topics: Algorithms; Animals; Azoxymethane; Bayes Theorem; Biometry; Colorectal Neoplasms; Gene Expression Profiling; Genetic Predisposition to Disease; Mice; Mice, Inbred Strains; Models, Genetic; Oligonucleotide Array Sequence Analysis; Species Specificity; Time Factors

2007
Green tea polyphenols inhibit colorectal aberrant crypt foci (ACF) formation and prevent oncogenic changes in dysplastic ACF in azoxymethane-treated F344 rats.
    Carcinogenesis, 2008, Volume: 29, Issue:1

    Topics: Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Flavonoids; Phenols; Polyphenols; Precancerous Conditions; Rats; Rats, Inbred F344; Tea

2008
Chemopreventive effect of a vitamin D(3) analog, alfacalcidol, on colorectal carcinogenesis in mice with ulcerative colitis.
    Anti-cancer drugs, 2007, Volume: 18, Issue:10

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Azoxymethane; Colitis, Ulcerative; Colorectal Neoplasms; Dextran Sulfate; Female; Hydroxycholecalciferols; Mice; Mice, Inbred CBA; RNA, Messenger; Thymidine Kinase

2007
Serial endoscopy in azoxymethane treated mice using ultra-high resolution optical coherence tomography.
    Cancer biology & therapy, 2007, Volume: 6, Issue:11

    Topics: Adenoma; Animals; Azoxymethane; Colon; Colorectal Neoplasms; Disease Models, Animal; Disease Progression; Endoscopy, Gastrointestinal; Gastrointestinal Neoplasms; Mice; Tomography, Optical Coherence

2007
Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage.
    Cancer research, 2007, Dec-15, Volume: 67, Issue:24

    Topics: Animals; Azoxymethane; beta Catenin; Colorectal Neoplasms; Disease Models, Animal; Disease Progression; DNA Mutational Analysis; Endoscopy; Humans; Mice; Neoplasm Invasiveness; Polyploidy

2007
Lack of interleukin-4 receptor alpha chain-dependent signalling promotes azoxymethane-induced colorectal aberrant crypt focus formation in Balb/c mice.
    The Journal of pathology, 2008, Volume: 214, Issue:5

    Topics: Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colorectal Neoplasms; Disease Models, Animal; Female; Interleukin-13; Interleukin-4; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Mice, Knockout; Precancerous Conditions; Receptors, Cell Surface; Signal Transduction; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2008
Susceptibility of Snark-deficient mice to azoxymethane-induced colorectal tumorigenesis and the formation of aberrant crypt foci.
    Cancer science, 2008, Volume: 99, Issue:4

    Topics: Animals; Azoxymethane; Body Weight; Carcinogens; Colorectal Neoplasms; Female; Gastrointestinal Tract; Genetic Predisposition to Disease; Mice; Mice, Mutant Strains; Obesity; Precancerous Conditions; Protein Serine-Threonine Kinases; Risk Factors

2008
5-aminosalicylic acid inhibits colitis-associated colorectal dysplasias in the mouse model of azoxymethane/dextran sulfate sodium-induced colitis.
    Inflammatory bowel diseases, 2008, Volume: 14, Issue:10

    Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; Mesalamine; Mice; Random Allocation

2008
A new experimental model for colorectal carcinogenesis in the rat.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 1994, Volume: 13, Issue:1

    Topics: Animals; Azoxymethane; Bile; Colorectal Neoplasms; Disease Models, Animal; Injections; Male; Rats; Rats, Sprague-Dawley

1994
Effect of docosahexaenoic acid on azoxymethane-induced colon carcinogenesis in rats.
    Cancer letters, 1994, Aug-15, Volume: 83, Issue:1-2

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinoma; Cholesterol; Colorectal Neoplasms; Docosahexaenoic Acids; Fatty Acids; Male; Rats; Rats, Inbred F344; Triglycerides

1994
Cyclooxygenase-1 and cyclooxygenase-2 gene expression in human colorectal adenocarcinomas and in azoxymethane induced colonic tumours in rats.
    Gut, 1996, Volume: 38, Issue:1

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Animals; Azoxymethane; Base Sequence; Carcinogens; Colonic Neoplasms; Colorectal Neoplasms; Female; Gene Expression; Humans; Male; Middle Aged; Molecular Sequence Data; Oligonucleotide Probes; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Rats; RNA, Messenger

1996
Dietary fat and fiber differentially alter intracellular second messengers during tumor development in rat colon.
    Carcinogenesis, 1996, Volume: 17, Issue:6

    Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Ceramides; Cocarcinogenesis; Colon; Colorectal Neoplasms; Dietary Fats; Dietary Fiber; Diglycerides; Intestinal Mucosa; Isoenzymes; Phospholipase C gamma; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Type C Phospholipases

1996
Promotion of colorectal neoplasia in experimental murine ulcerative colitis.
    Gut, 1996, Volume: 39, Issue:1

    Topics: Animals; Azoxymethane; Carcinogens; Chronic Disease; Colitis, Ulcerative; Colon; Colorectal Neoplasms; Dextran Sulfate; Female; Intestinal Mucosa; Mice; Mice, Inbred CBA; Necrosis; Thymidine Kinase; Thymidylate Synthase

1996
Inhibitory effects of lemon grass (Cymbopogon citratus Stapf) on formation of azoxymethane-induced DNA adducts and aberrant crypt foci in the rat colon.
    Carcinogenesis, 1997, Volume: 18, Issue:5

    Topics: Animals; Antimutagenic Agents; Azoxymethane; Colon; Colorectal Neoplasms; DNA Adducts; Glucuronidase; Male; Plant Extracts; Plants, Medicinal; Poaceae; Rats; Rats, Inbred F344; Thailand

1997
Relationship between fecal bile acids and the occurrence of colorectal neoplasia in experimental murine ulcerative colitis.
    Digestion, 1998, Volume: 59, Issue:1

    Topics: Adenocarcinoma; Animals; Azoxymethane; Bile Acids and Salts; Carcinogenicity Tests; Carcinogens; Chromatography, High Pressure Liquid; Colitis, Ulcerative; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Mice; Severity of Illness Index

1998
Absence of an inhibitory effect of a vegetables-fruit mixture on the initiation and promotion phases of azoxymethane-induced colorectal carcinogenesis in rats fed low- or high-fat diets.
    Nutrition and cancer, 1998, Volume: 30, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Diet; Diet, Fat-Restricted; Dietary Fats; Fruit; Male; Rats; Rats, Inbred F344; Vegetables

1998
Mutations of the Apc gene in experimental colorectal carcinogenesis induced by azoxymethane in F344 rats.
    British journal of cancer, 1998, Volume: 77, Issue:12

    Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colorectal Neoplasms; DNA, Neoplasm; Epithelium; Genes, APC; Intestinal Mucosa; Male; Mutation; Polymerase Chain Reaction; Precancerous Conditions; Rats; Rats, Inbred F344

1998
Azoxymethane-induced aberrant crypt foci and colorectal tumors in F344 rats: sequential analysis of growth.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1999, Volume: 31, Issue:3

    Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinoma, Signet Ring Cell; Cell Division; Colorectal Neoplasms; Hyperplasia; Intestinal Mucosa; Male; Precancerous Conditions; Rats; Rats, Inbred F344

1999
Expression of the cyclin D1 gene in rat colorectal aberrant crypt foci and tumors induced by azoxymethane.
    Cancer letters, 1999, Jun-01, Volume: 140, Issue:1-2

    Topics: Adenocarcinoma; Animals; Azoxymethane; Bromodeoxyuridine; Cell Division; Cell Nucleus; Colorectal Neoplasms; Cyclin D1; Cytoplasm; Gene Expression; Hyperplasia; Intestinal Mucosa; Male; Rats; Rats, Inbred F344; Time Factors

1999
Modifying effects of a flavonoid morin on azoxymethane-induced large bowel tumorigenesis in rats.
    Carcinogenesis, 1999, Volume: 20, Issue:8

    Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Antioxidants; Azoxymethane; Carcinogens; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Glutathione Transferase; Male; Polyamines; Precancerous Conditions; Rats; Rats, Inbred F344

1999
Polyethylene-glycol suppresses colon cancer and causes dose-dependent regression of azoxymethane-induced aberrant crypt foci in rats.
    Cancer research, 1999, Oct-15, Volume: 59, Issue:20

    Topics: Animals; Azoxymethane; Body Weight; Colorectal Neoplasms; Dose-Response Relationship, Drug; Feces; Female; Male; Polyethylene Glycols; Precancerous Conditions; Rats; Rats, Inbred F344

1999
Effect of vegetable and carotenoid consumption on aberrant crypt multiplicity, a surrogate end-point marker for colorectal cancer in azoxymethane-induced rats.
    Carcinogenesis, 1999, Volume: 20, Issue:12

    Topics: Animals; Azoxymethane; Biomarkers, Tumor; Body Weight; Bromodeoxyuridine; Carcinogens; Carotenoids; Colorectal Neoplasms; Food; Rats; Vegetables

1999
Cancer immunomodulation by carbohydrate ligands for the lymphocyte receptor NKR-P1.
    International journal of oncology, 2000, Volume: 16, Issue:2

    Topics: Animals; Antigens, Surface; Antimetabolites, Antineoplastic; Azoxymethane; Carcinogens; Colorectal Neoplasms; Drug Carriers; Drug Screening Assays, Antitumor; Escherichia coli; Fluorouracil; G(M2) Ganglioside; Lectins, C-Type; Liposomes; Male; NK Cell Lectin-Like Receptor Subfamily B; Oligosaccharides; Rats; Rats, Sprague-Dawley

2000
Resveratrol depresses the growth of colorectal aberrant crypt foci by affecting bax and p21(CIP) expression.
    Carcinogenesis, 2000, Volume: 21, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Azoxymethane; bcl-2-Associated X Protein; Carcinogens; Cell Division; Colon; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Growth Inhibitors; Intestinal Mucosa; Male; Precancerous Conditions; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred F344; Rectum; Resveratrol; Stilbenes

2000
Folate deficiency reduces the development of colorectal cancer in rats.
    Carcinogenesis, 2000, Volume: 21, Issue:12

    Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Colorectal Neoplasms; Folic Acid; Folic Acid Deficiency; Intestinal Neoplasms; Male; Rats; Rats, Sprague-Dawley

2000
Effect of dietary galacto-oligosaccharides on azoxymethane-induced aberrant crypt foci and colorectal cancer in Fischer 344 rats.
    Carcinogenesis, 2001, Volume: 22, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Body Weight; Carcinogens; Colorectal Neoplasms; Diet; Dose-Response Relationship, Drug; Eating; Energy Intake; Galactosides; Male; Oligosaccharides; Precancerous Conditions; Rats; Rats, Inbred F344

2001
Enhanced formation of azoxymethane-induced colorectal adenocarcinoma in gammadelta T lymphocyte-deficient mice.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:8

    Topics: Adenocarcinoma; Animals; Azoxymethane; Colorectal Neoplasms; Disease Progression; Homozygote; Hyperplasia; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes

2001
Inhibition of azoxymethane-induced aberrant crypt foci formation in rat colorectum by whole leaf Aloe arborescens Miller var. natalensis Berger.
    Phytotherapy research : PTR, 2001, Volume: 15, Issue:8

    Topics: Aloe; Animals; Antineoplastic Agents; Azoxymethane; Colorectal Neoplasms; Liver; Male; NAD(P)H Dehydrogenase (Quinone); Phytotherapy; Plant Extracts; Plant Leaves; Precancerous Conditions; Rats; Rats, Inbred F344

2001
Comparative study of histopathologic characterization of azoxymethane-induced colon tumors in three inbred rat strains.
    Comparative medicine, 2002, Volume: 52, Issue:1

    Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Biomarkers, Tumor; Carcinogens; Colorectal Neoplasms; Disease Models, Animal; Female; Fluorescent Antibody Technique, Indirect; Immunoenzyme Techniques; Injections, Subcutaneous; Male; Polymorphism, Genetic; Rats; Rats, Inbred F344; Reproducibility of Results; Species Specificity; Time Factors

2002
Dietary cholesterol enhances the induction and development of colonic preneoplastic lesions in C57BL/6J and BALB/cJ mice treated with azoxymethane.
    Cancer letters, 1992, Apr-30, Volume: 63, Issue:3

    Topics: Animals; Azoxymethane; Cell Division; Cholesterol, Dietary; Cocarcinogenesis; Colorectal Neoplasms; Female; Intestines; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Precancerous Conditions

1992
Increased cell membrane arachidonic acid in experimental colorectal tumours.
    Gut, 1991, Volume: 32, Issue:4

    Topics: Animals; Arachidonic Acids; Azoxymethane; Cell Membrane; Chromatography, Gas; Colon; Colorectal Neoplasms; Dietary Fats; Intestinal Mucosa; Male; Rats; Rats, Inbred Strains

1991
Inhibition of experimental colorectal carcinogenesis by dietary N-6 polyunsaturated fats.
    Carcinogenesis, 1990, Volume: 11, Issue:12

    Topics: Adenoma; Adipose Tissue; Animals; Arachidonic Acid; Arachidonic Acids; Azoxymethane; Carcinoma; Cell Membrane; Colorectal Neoplasms; Fats, Unsaturated; Fatty Acids; Intestinal Mucosa; Linoleic Acid; Linoleic Acids; Male; Oleic Acid; Oleic Acids; Palmitic Acid; Palmitic Acids; Rats; Rats, Inbred Strains; Stearic Acids; Weight Gain

1990