azoxymethane has been researched along with Colitis in 320 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 25 (7.81) | 29.6817 |
| 2010's | 201 (62.81) | 24.3611 |
| 2020's | 94 (29.38) | 2.80 |
| Authors | Studies |
|---|---|
| Gong, W; Gu, G; Hong, Z; Liu, J; Liu, P; Ren, H; Ren, J; Wang, G; Wu, X; Zhao, F; Zhao, Y; Zheng, T | 1 |
| Chen, Z; Han, Y; Jiang, M; Liu, M; Pan, S; Tang, Z; Wang, S; Wang, Y; Xu, N; Yin, K; Zhang, G; Zhu, H | 1 |
| Allaman, MM; Asim, M; Barry, DP; Coburn, LA; Gobert, AP; Hardbower, DM; Piazuelo, MB; Polosukhina, D; Singh, K; Washington, MK; Wilson, KT | 1 |
| Donthi, D; Hong, H; Lertpiriyapong, K; Marie, MA; Sanderlin, EJ; Satturwar, S; Yang, LV | 1 |
| He, L; Li, W; Ma, Y; Sun, P; Wang, H; Zhang, X; Zhao, X | 1 |
| Chen, GQ; Chen, J; Li, Z; Liu, G; Wu, F; Zhang, S; Zhang, Y | 1 |
| Allaman, MM; Asim, M; Barry, DP; Coburn, LA; Delgado, AG; Finley, JL; Gobert, AP; Latour, YL; Luis, PB; McNamara, KM; Piazuelo, MB; Schneider, C; Sierra, JC; Singh, K; Smith, TM; Washington, MK; Wilson, KT; Zhao, S | 1 |
| Bou-Dargham, M; Chen, YH; Etwebi, Z; Goldsmith, JR; Hood, R; Lengner, C; Li, M; Liu, S; Lou, Y; Spitofsky, N; Sun, H; Tian, Y | 1 |
| Li, JC; Rui, XL; Shao, FP; Xu, L; Yang, Y; Yin, DK; Zhang, MM | 1 |
| Deng, J; Han, L; Li, Y; Shi, J; Wang, H; Yan, Y; Yuan, X; Zhang, H; Zhao, H; Zhao, L; Zhao, Y; Zou, F | 1 |
| Adileh, M; Baslan, T; Brown, AM; Fuks, Z; Hsu, KS; Hua, G; Klingler, S; Kolesnick, R; Martin, ML; Paty, PB; Zhang, Z | 1 |
| Kimura, Y; Sumiyoshi, M | 1 |
| Gan, Y; Gao, C; Huang, B; Liu, Y; Pan, D; Tang, Z | 1 |
| Eferl, R; Gushchina, V; Kallay, E; Kupper, N; Manhardt, T; Mesteri, I; Moritsch, S; Müller, C; Piatek, K; Salzmann, M; Schepelmann, M; Vlasaty, A | 1 |
| Jiang, S; Ma, F; Mu, G; Qian, F; Song, Y; Sun, M; Tuo, Y; Wang, A | 1 |
| Chen, K; Gao, Z; Jia, H; Shi, Y; Wang, Z; Yuan, Y; Yue, T; Zeng, X | 1 |
| Cai, B; Chen, H; Guo, Y; Wang, X; Yao, Q; Ye, C; Zhang, F; Zhang, J; Zhang, Z | 1 |
| Kim, M; Kim, Y; Lee, S; Moon, S | 1 |
| Chang, J; Geng, Z; Hao, X; Liu, J; Tan, X; Wang, Z; Yan, S | 1 |
| Kamakura, Y; Kawakami, S; Kojima, H; Kubota, A; Maeda, H; Miyashita, K; Murase, W; Mutoh, M; Ohta, T; Tanaka, T; Terasaki, M | 1 |
| Chen, Q; Chu, Y; Dai, Y; Fang, Y; Lv, C; Wei, Z; Xia, Y; Yun, X; Zhang, Q; Zhu, Y | 1 |
| Aladhami, A; Bader, JE; Chatzistamou, I; Cunningham, P; Enos, RT; Helms, H; Martinez-Muñiz, G; Noneman, MT; Patton, E; Shin, HK; Sumal, A; Unger, C; Velázquez, KT | 1 |
| Dong, S; Ismael, M; Lü, X; Shan, Y; Wang, T; Wang, X; Zheng, J | 1 |
| Begun, J; Davies, JM; Florin, TH; Giri, R; Hasnain, SZ; McGuckin, MA; Sheng, YH; Wang, R; Wong, KY; Yang, Y | 1 |
| Chen, Q; Fu, J; Han, H; Lin, H; Lu, G; Ma, X; Qi, J; Wen, Z; Yang, M; Yang, X; Yang, Y; Yin, T | 1 |
| Jiang, Q; Jones-Hall, Y; Nakatsu, C; Zhao, Y | 1 |
| Chen, IY; Hu, ML; Huang, WT; Lian, WS; Wang, FS; Yang, CH; Yang, JW; Yang, MY | 1 |
| Archer, A; Birgersson, M; Hases, L; Indukuri, R; Williams, C | 1 |
| Chen, C; Chen, G; Chen, X; Du, J; Gao, Y; Li, W; Ning, H; Pang, L; Qi, Y; Shen, W; Shi, R; Sui, X; Sun, Y; Wang, H; Wu, Y; Zhai, W; Zhao, W; Zhou, X | 1 |
| Hong, Y; Jia, ML; Li, YT; Liu, XM; Liu, ZQ; Yan, PK; Zhu, WT | 1 |
| Bouznad, N; Brocker, T; Friedrich, V; Garzetti, D; Hermeking, H; Krebs, S; Krug, AB; Lutz, K; Matzek, D; Metzger, R; Öllinger, R; Rad, R; Rokavec, M; Schäfer, Y; Stecher, B; von Armansperg, B; Winheim, E; Winter, L | 1 |
| Ando, Y; Aoi, M; Fukui, T; Horitani, S; Matsumoto, Y; Naganuma, M; Okazaki, K; Tanaka, H; Tomiyama, T; Tsuneyama, K; Uragami, T | 1 |
| Burmeister, J; Gebhardt, JM; Giese, NA; Giese, T; Harnoss, JM; Kennel, KB; Radhakrishnan, P; Salfenmoser, M; Schneider, M; Strowitzki, MJ; Taylor, CT; Wielockx, B | 1 |
| Blecker, C; Fan, X; Guo, H; Qin, P; Ren, G; Richel, A; Teng, C; Yang, X; Zhang, L | 1 |
| Bian, ZL; Chen, BQ; Chen, L; Chen, WJ; Cheng, TC; Feng, N; Ju, LL; Li, M; Liu, Y; Liu, YC; Liu, ZX; Luo, LL; Shao, JG; Wang, Y | 1 |
| Huang, XH; Jiang, B; Ni, M; Wang, L; Xu, YY; Zhang, QQ; Zhang, R; Zhang, YQ; Zhao, Q | 1 |
| Fan, RJ; Fang, MD; Ren, J; Tu, LL; Yao, WX; Zhang, YM; Zuo, BW | 1 |
| Chen, Y; Kang, C; Li, J; Liu, Z; Zhang, Q; Zhu, W | 1 |
| Arcos, M; Liu, Z; Martin, DR; Xue, X | 1 |
| An, SY; Kim, J; Kim, SW; Lee, DB; Pyo, SS; Yoon, DW | 1 |
| Jiang, Q; Jones-Hall, Y; Liu, KY; Nakatsu, CH; Wang, Q | 1 |
| Kettawan, A; Prombutara, P; Rungruang, T; Tajasuwan, L; Wunjuntuk, K | 1 |
| Kimura, Y; Sumiyoshi, M; Taniguchi, M | 1 |
| Guo, X; Pu, W; Tang, S; Wang, X; Zhang, H; Zhang, T | 1 |
| Chen, C; El-Nezami, H; Ismaiah, MJ; Leung, HKM; Lo, EKK; Zhang, F | 1 |
| Feng, YL; Jia, J; Luo, YY; Ouyang, H; Wan, MQ; Xie, XX; Yang, X; Yu, J | 1 |
| Bullard, BM; Cardaci, TD; Fan, D; Hofseth, LJ; Huss, AR; McDonald, SJ; Murphy, EA; VanderVeen, BN | 1 |
| Chung, JH; Hong, GH; Lee, SY; Park, KY | 1 |
| Fukui, T; Honzawa, Y; Horitani, S; Matsumoto, Y; Naganuma, M; Okazaki, K; Suzuki, R; Tahara, T; Tanimura, Y; Tomiyama, T | 1 |
| Duan, J; Duan, W; Gao, Q; Li, J; Mao, T; Wang, M; Yan, J | 1 |
| Al-Omari, M; Al-Omari, T; Al-Qauod, K; Batainah, N; Janciauskiene, S; Olejnicka, B | 1 |
| Chen, Y; Li, P; Liang, J; Luo, X; Wang, Q; Xie, X; Yang, C; Zhang, M; Zhou, L | 1 |
| Abreu, AC; Aydos, RD; Fagundes, LS; Gonçalves, AF; Neves, MB; Ramalho, RT; Silva Junior, UND; Takita, LC | 1 |
| Dzhalilova, D; Fokichev, N; Makarova, O; Zolotova, N | 1 |
| Chen, X; Deng, Y; He, F; Huang, X; Tian, L; Wang, M; Yang, W; Yin, W; Zhou, H | 1 |
| Arias-Romero, LE; Callejas, BE; Chirino, YI; Delgado-Buenrostro, NL; León-Cabrera, SA; Martínez-Saucedo, D; Mendoza-Rodríguez, MG; Pérez-Plasencia, C; Reyes-Martínez, S; Rodríguez-Sosa, M; Sánchez-Barrera, CA; Terrazas, LI; Vaca-Paniagua, F; Villamar-Cruz, O | 1 |
| Djurhuus, D; Nielsen, B; Olsen, J; Pedersen, AE; Sadowska, Z; Tougaard, P; Yassin, M | 1 |
| Chen, X; Decker, EA; Kim, D; Ma, Q; Park, Y; Qi, W; Sanidad, KZ; Yang, R; Zhang, G; Zhang, J | 1 |
| El-Daly, SM; El-Khayat, Z; Hussein, J; Omara, EA; Youness, ER | 1 |
| Li, Y; Liu, G; Liu, J; Ma, Y; Pan, Z; She, J; Wei, Q; Xia, H; Zhang, M; Zhang, RX | 1 |
| Guo, M; Li, Z | 1 |
| Oyama, T; Sugie, S; Tanaka, T | 1 |
| Gao, Y; Hammad, A; Namani, A; Shi, HF; Tang, X; Zheng, ZH | 1 |
| Chen, X; Han, W; Li, Y; Shi, L; Wan, J; Wang, H; Xie, B | 1 |
| Chac, D; DePaolo, RW; Kim, JH; Kordahi, MC | 1 |
| Chen, N; Cheng, L; Dai, L; Deng, H; Dong, Z; Fang, C; Fu, J; Ji, Y; Li, J; Liu, Y; Shi, G; Su, X; Wang, H; Wang, W; Yang, Y; Yu, Y; Zhang, H; Zhang, S | 1 |
| Deguchi, A; Kato, S; Kawanishi, S; Maebashi, U; Matsumoto, K; Morita, A; Motoyoshi, A; Nakahara, T; Nakamoto, T; Nishimura, K; Sueyoshi, M; Takata, K; Tominaga, M | 1 |
| Eun, CS; Han, DS; Jo, SV; Lee, AR; Lee, JG; Park, CH | 1 |
| Aggarwal, A; Baumgartner, M; Gasche, C; Gröschel, C; Heiden, D; Kallay, E; Karuthedom George, S; Lang, M; Manhardt, T; Marculescu, R; Mesteri, I; Prinz-Wohlgenannt, M; Schepelmann, M; Tennakoon, S; Trawnicek, L | 1 |
| Chen, D; Huang, Z; Liu, Y; Ma, H; Ouyang, G; Wang, J; Wu, T; Zhao, X | 1 |
| Chartier, LC; Hebart, ML; Howarth, GS; Mashtoub, S; Whittaker, AL | 1 |
| Berhow, M; Gonzalez de Mejia, E; Luna-Vital, D; Mazewski, C | 1 |
| Hong, JE; Hwang, S; Jo, M; Lee, CG; Park, CO; Rhee, KJ | 1 |
| Benninghoff, AD; Hintze, KJ; Hunter, AH; Monsanto, SP; Pestka, JJ; Phatak, S; Rodriguez, DM; Ward, RE; Wettere, AJV | 1 |
| Li, H; Li, Z; Shan, S; Shi, J; Yang, R; Zhang, C | 1 |
| Gao, Y; Meng, X; Sun, X; Wang, B; Wang, X; Wang, Y; Yoshikai, Y; Zhang, X | 1 |
| Bian, X; Chan, AWH; Chan, FKL; Coker, OO; El-Omar, E; Nakatsu, G; Sung, JJY; Wei, H; Wu, J; Yu, J; Zhao, L; Zhao, R; Zhou, Y | 1 |
| Alabbas, S; Begun, J; Davies, J; Fairlie, DP; Florin, TH; Giri, R; Hasnain, S; He, Y; Hooper, J; Kijanka, G; Lucke, AJ; McGuckin, MA; McWhinney, B; Movva, R; Oancea, I; Schreiber, V; Sheng, YH; Wu, A | 1 |
| Diao, F; Li, X; Li, Y; Mei, Q; Niu, Y; Sun, Y; Zhou, H | 1 |
| Deng, T; Liu, M; Wan, X; Xie, W | 1 |
| Huang, X; Jiang, Z; Li, H; Li, L; Sun, L; Wang, T; Wang, X; Xing, X; Zhang, L; Zhang, X | 1 |
| Bai, R; Boardman, LA; Bode, AM; Chang, X; Chen, H; Dong, Z; Lim, DY; Ma, WY; Ryu, J; Wang, K; Wang, Q; Wang, T; Yao, K; Zhang, T | 1 |
| Becker, C; Fichna, J; Jacenik, D; Kordek, R; Krajewska, WM; Sałaga, M; Schodel, L; Szymaszkiewicz, A; Zatorski, H; Zielińska, M | 1 |
| Chen, TH; Chen, YH; Chiu, CC; Chuang, HL; Huang, WC; Hung, SW; Lee, YP; Lin, TJ; Wang, YC | 1 |
| Amini, N; Andreatos, N; Angelou, A; Antoniou, E; Buettner, S; Kamphues, C; Margonis, GA; Munir, M; Papalois, AE; Pikouli, A; Pikoulis, E; Pulvirenti, A; Sarantis, P; Theocharis, S; Theodoropoulos, G; Wang, J; Zografos, GC | 1 |
| Horiguchi, H; Kadomatsu, T; Miyata, K; Morinaga, J; Moroishi, T; Oike, Y; Sato, M; Terada, K; Torigoe, D | 1 |
| Bayrer, JR; Bisanz, JE; Bowman, C; Braverman, KN; Chawla, A; Escalante, V; Ganeshan, K; Man, K; Patterson, A; Tian, Y; Turnbaugh, PJ; Wang, B | 1 |
| Bohnenberger, H; Meers, GK; Muzzi, C; Reichardt, HM; Reichardt, SD; Twomey, E; Watanabe, N | 1 |
| Im, S; Jiang, Q; Jones-Hall, Y; Nakatsu, C; Yang, C; Zhao, Y | 1 |
| Barrett, CW; Burk, RF; Chen, X; Denson, LA; Haberman, Y; Hendren, JR; Hill, KE; Hyams, JS; Keating, CE; Marsh, BJ; Motley, AK; Pilat, JM; Reddy, VK; Rosen, MJ; Shi, C; Short, SP; Washington, MK; Williams, CS; Wilson, KT; Zemper, AE | 1 |
| Epifano, F; Fiorito, S; Genovese, S; Ibuka, T; Ideta, T; Kubota, M; Maruta, A; Miyazaki, T; Mizutani, T; Sakai, H; Shimizu, M; Shirakami, Y; Taddeo, VA; Tanaka, T | 1 |
| Board, PG; Casarotto, MG; Dahlstrom, JE; Fernando, N; Hughes, MM; O'Neill, LAJ; Rooke, M; Takahashi, S; Tummala, P | 1 |
| Chen, S; Chen, Y; Gao, J; Hou, S; Hu, J; Liang, J; Lin, J; Lu, Y; Wang, B; Yuan, X | 1 |
| Basu, S; Dannenberg, AJ; Ito, N; Makino, T; Montrose, DC | 1 |
| Lee, HJ; Lee, SM; Lim, YI; Park, ES; Park, KY; Yu, T | 1 |
| Aparna, JS; Athira, SR; Babu, A; Harikumar, KB; James, S; Kumar, SS; Lankadasari, MB; Mohammed, S; Namitha, NN; Paul, AM; Reshmi, G; Vijayan, Y | 1 |
| Fan, Y; Huang, MQ; Jia, XK; Lan, ML; Li, XY; Wu, SS; Xu, SH; Xu, W; Zhu, HC | 1 |
| Abba, MC; Blidner, AG; Cagnoni, AJ; Croci, DO; Cutine, AM; Gatto, SG; Giribaldi, ML; Mariño, KV; Morales, RM; Rabinovich, GA; Salatino, M | 1 |
| Chen, L; Cheung, S; Feng, Y; He, W; Li, Z; McDonald, F; Tao, L; Wang, G; Yang, J; Yang, M; Zhang, Y; Zhong, X | 1 |
| Elshaer, M; Hammad, A; Namani, A; Tang, X; Wang, XJ; Zheng, ZH | 1 |
| Ahn, JY; An, BC; Choi, O; Chung, MJ; Chung, Y; Kim, JF; Kim, TY; Kwon, SK; Park, HJ; Ryu, Y; Yoon, J; Yoon, YS | 1 |
| Álvarez-González, I; García-Cordero, JM; Jiménez-Martínez, C; Madrigal-Bujaidar, E; Madrigal-Santillán, E; Martínez-Palma, NY; Morales-González, JA; Paniagua-Pérez, R | 1 |
| Chen, C; Chen, J; Chen, R; Fang, L; Guo, C; Guo, D; Sang, T; Wang, X; Wang, Y; Wu, J | 1 |
| Liu, B; Liu, Y; Lü, X; Shan, Y; Wang, G; Wang, P; Wang, T; Wang, X; Yi, Y; Zhang, L; Zhou, Y | 1 |
| Ho, CT; Lee, PS; Nagabhushanam, K; Pan, MH | 1 |
| Arias-Romero, LE; Ávila-Moreno, F; Chirino, YI; Delgado-Buenrostro, NL; Delgado-Ramirez, YG; Gutierrez-Cirlos, EB; Ledesma-Soto, Y; Leon-Cabrera, SA; Molina-Guzman, E; Pérez-Plasencia, CG; Rodríguez-Sosa, M; Terrazas, LI; Vaca-Paniagua, F; Vázquez-Sandoval, A | 1 |
| Amberg, N; Botti, G; Cardone, C; Ciardiello, F; Diamanti, MA; Dienes, HP; Eferl, R; Greten, FR; Holcmann, M; Kenner, L; Liguori, G; Linder, M; Martinelli, E; Pathria, P; Paul, MC; Prager, GW; Rose-John, S; Sibilia, M; Srivatsa, S; Timelthaler, G; Wrba, F | 1 |
| Bellamkonda, K; Chandrashekar, NK; Douglas, D; Osman, J; Savari, S; Sjölander, A | 1 |
| Hayashi, SM; Kangawa, Y; Kataoka, A; Koyama, N; Ohsumi, T; Shibutani, M; Tanaka, T; Yoshida, T | 1 |
| Berger, FG; Bridges, AE; Browning, DD; Hou, Y; Islam, BN; Kim, S; Kolhe, R; Rodriguez, PC; Sharman, SK; Singh, N; Sridhar, S; Trillo-Tinoco, J | 1 |
| Dai, X; Gui, G; Li, K; Liu, J; Xiao, Y; Yang, H | 1 |
| He, L; Luan, Z; Lv, H; Qian, J; Tan, B; Wang, H; Xin, Y; Yang, H; Yu, S; Zhao, X; Zhou, W; Zhou, Y | 1 |
| Chang, EB; Du, W; He, TC; Huang, WH; Musch, MW; Wan, JY; Wang, CZ; Wang, Y; Williams, S; Yu, C; Yuan, CS; Zhang, CF | 1 |
| Dey, M; Liu, Y | 1 |
| González de Mejía, E; Loarca-Piña, G; Luna-Vital, DA | 1 |
| Blackburn, C; Bulek, K; Carman, J; Chen, X; Hamilton, TA; Hao, Y; Huang, YH; Kalady, MF; Li, X; Liu, C; Ouyang, W; Su, B; Wang, X; Wang, Z; Wu, L; Yang, WP; Zepp, JA; Zhao, J; Zhu, J | 1 |
| Berggren, KL; Beswick, EJ; Gan, GN; Ray, AL; Restrepo Cruz, S | 1 |
| García-Sanmartín, J; Martínez, A; Martínez-Herrero, S; Narro-Íñiguez, J; Ochoa-Callejero, L; Rubio-Mediavilla, S | 1 |
| Chen, P; Hou, Z; Jia, H; Shen, B; Song, H; Sun, Y; Wang, W | 1 |
| Arning, E; Ashcraft, P; Cook, B; Genta, RM; Han, J; Holm, J; Jackson, D; Souza, RF; Sweetman, L; Theiss, AL; Turner, K; Venuprasad, K; Wang, X | 1 |
| An, HJ; Cheon, SY; Chung, KS; Lee, M; Roh, SS | 1 |
| Agle, KA; Chen, X; Drobyski, WR; Huang, YW; Oshima, K; Pan, P; Wang, LS; Yearsley, MM; Yu, J; Zhang, J | 1 |
| Cheng, D; Fang, M; Gao, L; Gaspar, JM; Guo, Y; Hart, RP; Kong, AN; Li, W; Sargsyan, D; Su, ZY; Verzi, MP; Wang, C; Wu, R; Yin, R; Zhang, C | 1 |
| Cui, SX; Qu, XJ; Wang, F; Zhang, YS | 1 |
| Ding, Y; Du, Q; Hu, R; Liu, X; Zhang, X; Zhou, W | 1 |
| Kim, JK; Park, JH | 1 |
| Gong, D; Hu, JL; Liu, LQ; Nie, SP; Shen, MY; Xie, MY; Yu, Q | 1 |
| Fang, J; Qin, Y; Weng, Z; Xie, Y; Yuan, T | 1 |
| Ji, G; Sun, L; Tian, Y; Xu, Q; Ye, Y | 1 |
| Brambilla, SR; Camargo, JA; Carvalheira, JBC; Mendes, MCS; Paulino, DS; Persinoti, GF | 1 |
| Jia, W; Luo, Y; Niu, W; Wang, J; Wu, Z; Yang, M; Zhang, H; Zhang, X | 1 |
| Andreatos, N; Angelou, A; Antoniou, E; Damaskos, C; Garmpis, N; Margonis, GA; Papalois, A; Theocharis, S; Theodoropoulos, G; Xiao, W; Yuan, C; Zacharioudaki, A; Zografos, G | 1 |
| Grill, JI; Herbst, A; Kolligs, FT; Marschall, MK; Neumann, J; Ofner, A; Wolf, E; Zierahn, H | 1 |
| Dubé, PE; Girish, N; Liu, CY; Polk, DB; Washington, MK | 1 |
| Ahn, GO; Gu, H; Im, SH; Jeong, S; Kim, HJ; Kim, J; Kim, YE; Lee, M; Lee, YJ; Sung, YC; Weissman, IL; Yeo, S | 1 |
| Chastre, E; Jordan, P; Kotelevets, L; Lehy, T; Mamadou, G; Walker, F | 1 |
| Dong, YW; Feng, Y; Guo, XY; Jiang, WL; Lu, LG; Song, YN; Xiao, JH | 1 |
| Chang, YY; Huang, WJ; Jeng, YM; Jhuang, YL; Yang, CY; Yu, IS; Yu, LC | 1 |
| Barone, M; Di Leo, A; Giorgio, F; Girardi, B; Iannone, A; Ierardi, E; Losurdo, G; Pricci, M; Principi, M | 1 |
| Booth, CJ; D'Souza, SS; Kartchner, BJ; Lee, EC; Malizia, RA; O'Connor, W; Sharp, SP; Stain, SC; Walrath, T | 1 |
| Cui, K; Li, M; Li, Y; Lin, H; Shu, HB; Wang, SY; Wang, YY; Xia, T; Xu, ZS; Zhang, HX | 1 |
| Cao, Q; Chen, M; Chen, T; Ji, W; Peng, S; Qiu, Y; Que, B; Yuan, G; Zhang, H | 1 |
| Kim, BG; Kim, DW; Kim, JS; Kim, JW; Koh, SJ; Lee, KL | 1 |
| Balboa, MA; Balsinde, J; Cubero, Á; García-Rostán, G; Győrffy, B; Lordén, G; Meana, C; Orduña, A; Peña, L | 1 |
| Masuda, J; Seko, T; Umemura, C; Yamashita, M; Yamashita, Y; Yamauchi, K; Yokozawa, M | 1 |
| Cai, X; Han, Y; Neto, C; Song, M; Tang, Z; Tata, A; Wang, Q; Wu, X; Xiao, H | 1 |
| Hu, C; Liu, C; Liu, S; Rong, J | 1 |
| Kim, N; Lee, DH; Lee, SM; Na, HY; Nam, RH; Sohn, SH; Song, CH; Surh, YJ | 1 |
| Chen, S; Jing, X; Li, M; Liu, H; Liu, Y; Sun, B; Sun, T; Tian, Y; Wang, H; Yang, C; Zhang, Q; Zhao, J; Zhao, Y; Zong, S | 1 |
| Cao, H; Dong, W; Liu, L; Liu, T; Ma, J; Wang, B; Wang, D; Wang, S; Xie, R; Zheng, R | 1 |
| Kamishima, M; Kawamura, T; Konno, H; Kurachi, K; Sakata, M; Setoh, M; Suzuki, K; Suzuki, Y; Takeuchi, H; Yamamoto, M | 1 |
| Hwang, S; Khalmuratova, R; Kim, JH; Kim, YS; Koh, SJ; Lee, GY; Lee, M; Park, JW; Shin, HW; Yoon, DW | 1 |
| Han, W; Li, W; Lv, X; Wang, H; Zhao, X | 1 |
| Arthur, JC; Rothemich, A | 1 |
| Bader, JE; Carson, JA; Carson, M; Chatzistamou, I; Enos, RT; Kubinak, JL; Murphy, EA; Nagarkatti, M; Pena, MM; Sougiannis, AT; VanderVeen, BN; Velazquez, KT; Walla, M | 1 |
| Bak, MJ; Jeong, WS; Truong, VL | 1 |
| Chen, J; Du, RL; Gu, B; Li, SZ; Pan, WM; Song, Y; Xiang, Y; Zhang, HH; Zhang, XD; Zhao, H | 1 |
| Araki, A; Asao, H; Gazi, MY; Jin, L; Nara, H; Nemoto, N; Takeda, Y | 1 |
| Angelou, A; Antoniou, E; Buettner, S; Faateh, M; Margonis, GA; Papalois, AE; Pikouli, A; Pikoulis, E; Theocharis, S; Theodoropoulos, G; Ventin, M; Wang, J; Zografos, GC | 1 |
| Awadallah, JR; El-Bana, MA; El-Daly, SM; Gamal-Eldeen, AM; Latif, YA; Medhat, D; Morsy, SM; Omara, EA | 1 |
| Fujita, M; Fukai, F; Ishibashi, K; Ito-Fujita, Y; Iyoda, T; Kodama, H; Okada, Y; Osawa, T; Sasada, M; Suzuki, H | 1 |
| Chen, M; Hou, Y; Li, P; Ma, X; Qiao, X; Sun, M; Wen, X; Yang, J; Zhang, L | 1 |
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| Caruso, R; Fantini, MC; Fina, D; Macdonald, TT; Monteleone, G; Pallone, F; Palmieri, G; Pellegrini, R; Sarra, M; Stolfi, C | 1 |
| Akanuma, M; Hayakawa, Y; Hikiba, Y; Hirata, Y; Ichijo, H; Ijichi, H; Ikenoue, T; Maeda, S; Nakagawa, H; Ogura, K; Omata, M; Otsuka, M; Sakamoto, K; Tateishi, K; Yoshida, H | 1 |
| Miyamoto, S; Murakami, A; Tanaka, T | 1 |
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| Barney, KA; Blevins, EA; Finkelman, FD; Flick, MJ; Harmel-Laws, E; Horowitz, NA; Kombrinck, KW; Palumbo, JS; Pinkerton, MD; Shaw, MA; Steinbrecher, KA; Talmage, KE; Witte, DP | 1 |
| An, MJ; Cheon, JH; Kim, HM; Kim, SA; Kim, SK; Kim, SW; Kim, TI; Kim, WH; Lee, SK; Park, JJ; Yang, KM | 1 |
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| Barrett, CW; Chaturvedi, R; Fingleton, B; Fischer, MA; Hiebert, SW; Ning, W; Washington, MK; Williams, A; Williams, CS; Wilson, KT | 1 |
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| Kim, JS; Park, SY; Seo, YR; Sung, MK | 1 |
| Hosokawa, M; Mikami, N; Miyashita, K; Tanaka, T; Yasui, Y | 1 |
| Bugni, JM; Jubbal, K; Karagiannides, I; Lawson, G; Pothoulakis, C; Rabadi, LA | 1 |
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| Gerling, M; Glauben, R; Habermann, JK; Kühl, AA; Lehr, HA; Loddenkemper, C; Siegmund, B; Zeitz, M | 1 |
| Caprioli, F; Caruso, R; Fantini, MC; Ferrero, S; Franceschilli, L; Franzè, E; MacDonald, TT; Monteleone, G; Monteleone, I; Pallone, F; Rizzo, A; Rotondi, A; Sarra, M; Sileri, P; Stolfi, C | 1 |
| Endlicher, E; Grunwald, N; Lechner, A; Neumann, ID; Obermeier, F; Peters, S; Reber, SO; Rümmele, P | 1 |
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| Budda, S; Butryee, C; Kupradinun, P; Lee, JS; Rungsipipat, A; Tuntipopipat, S; Wangnaithum, S | 1 |
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| Camargo, JA; Carvalheira, JBC; Carvalho, HF; Damas-Souza, DM; de Carvalho, RB; Dias, MM; Flores, MBS; Osório-Costa, F; Rocha, GZ; Ropelle, ER; Saad, MJA | 1 |
| Abolhassani, N; Calvo, JA; Eichinger, LW; Klungland, A; Lee, CY; Meira, LB; Moroski-Erkul, CA; Muthupalani, S; Nordstrand, LM; Samson, LD; Taghizadeh, K | 1 |
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| Erwin, CR; Guo, J; Liu, J; Schneider, JE; Stappenbeck, TS; Wakeman, D; Wandu, WS; Warner, BW | 1 |
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| Clarke, M; Das, S; Huels, D; Jamieson, T; Jung, A; Neumann, J; Nibbs, RJ; Olson, MF; Samuel, MS; Sansom, OJ; Steele, CW | 1 |
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| Kohno, H; Sugie, S; Suzuki, R; Tanaka, T | 3 |
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| Chang, WC; Clapper, ML; Cooper, HS; Coudry, RA; Devarajan, K; Gary, MA; Litwin, S; Lubet, RA | 1 |
| Hosokawa, M; Kohno, H; Murakami, A; Okumura, A; Takashima, S; Tanaka, T; Yoshitani, S | 1 |
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2 review(s) available for azoxymethane and Colitis
| Article | Year |
|---|---|
Murine models of colorectal cancer: the azoxymethane (AOM)/dextran sulfate sodium (DSS) model of colitis-associated cancer.
Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Mice | 2023 |
Murine Model for Colitis-Associated Cancer of the Colon.
Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Humans; Male; Mice | 2016 |
318 other study(ies) available for azoxymethane and Colitis
| Article | Year |
|---|---|
STING-mediated Syk Signaling Attenuates Tumorigenesis of Colitis‑associated Colorectal Cancer Through Enhancing Intestinal Epithelium Pyroptosis.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Pyroptosis; Syk Kinase | 2022 |
Stimulation of hypothalamic oxytocin neurons suppresses colorectal cancer progression in mice.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Hypothalamus; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Oxytocin; Pentacyclic Triterpenes | 2021 |
CCL11 exacerbates colitis and inflammation-associated colon tumorigenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Chemokine CCL11; Colitis; Colitis-Associated Neoplasms; Epithelial Cells; Mice; Mice, Knockout | 2021 |
GPR65 (TDAG8) inhibits intestinal inflammation and colitis-associated colorectal cancer development in experimental mouse models.
Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colon; Dextran Sulfate; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Humans; Inflammation; Inflammatory Bowel Diseases; Leukocytes; Mice; Mice, Knockout; Receptors, G-Protein-Coupled; Severity of Illness Index | 2022 |
High-fat diet aggravates colitis-associated carcinogenesis by evading ferroptosis in the ER stress-mediated pathway.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Dextran Sulfate; Diet, High-Fat; Disease Models, Animal; Ferroptosis; Mice; Mice, Inbred C57BL | 2021 |
Applications and Mechanism of 3-Hydroxybutyrate (3HB) for Prevention of Colonic Inflammation and Carcinogenesis as a Food Supplement.
Topics: 3-Hydroxybutyric Acid; Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL | 2021 |
Protective Role of Spermidine in Colitis and Colon Carcinogenesis.
Topics: Adenomatous Polyposis Coli Protein; alpha-Defensins; Animals; Azoxymethane; Carcinogenesis; Colitis; Colitis, Ulcerative; Colon; Colonic Neoplasms; Dextran Sulfate; Gastrointestinal Microbiome; Gene Expression Regulation; Humans; Intestinal Mucosa; Male; Mice; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Precancerous Conditions; Protective Factors; RNA, Messenger; Severity of Illness Index; Spermidine; Weight Loss | 2022 |
TIPE2 Promotes Tumor Initiation But Inhibits Tumor Progression in Murine Colitis-Associated Colon Cancer.
Topics: Animals; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colitis-Associated Neoplasms; Colon; Dextran Sulfate; Disease Models, Animal; Inflammation; Inflammatory Bowel Diseases; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL | 2022 |
Protective effect of Pai-Nong-San against AOM/DSS-induced CAC in mice through inhibiting the Wnt signaling pathway.
Topics: Animals; Azoxymethane; CD8-Positive T-Lymphocytes; Colitis; Dextran Sulfate; Disease Models, Animal; Drugs, Chinese Herbal; Glycogen Synthase Kinase 3 beta; Mice; Mice, Inbred C57BL; RNA, Ribosomal, 16S; Wnt Signaling Pathway | 2021 |
Pre-Administration of Berberine Exerts Chemopreventive Effects in AOM/DSS-Induced Colitis-Associated Carcinogenesis Mice via Modulating Inflammation and Intestinal Microbiota.
Topics: Animals; Azoxymethane; Berberine; Carcinogenesis; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Mice; Mice, Inbred C57BL; RNA, Ribosomal, 16S | 2022 |
Disruption of the crypt niche promotes outgrowth of mutated colorectal tumor stem cells.
Topics: Adenoma; Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Humans; Mice; Neoplastic Stem Cells | 2022 |
Two hydroxyflavanones isolated from Scutellaria baicalensis roots prevent colitis-associated colon cancer in C57BL/6 J mice by inhibiting programmed cell death-1, interleukin 10, and thymocyte selection-associated high mobility group box proteins TOX/TOX2
Topics: Animals; Apoptosis; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colon; Colonic Neoplasms; Cyclooxygenase 2; Dextran Sulfate; HMGB Proteins; Interleukin-10; Mice; Mice, Inbred C57BL; Programmed Cell Death 1 Receptor; Scutellaria baicalensis; Thymocytes; Tumor Microenvironment | 2022 |
Phycocyanin Ameliorates Colitis-Associated Colorectal Cancer by Regulating the Gut Microbiota and the IL-17 Signaling Pathway.
Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Interleukin-17; Mice; Mice, Inbred C57BL; Phycocyanin; Signal Transduction | 2022 |
AOM/DSS Induced Colitis-Associated Colorectal Cancer in 14-Month-Old Female Balb/C and C57/Bl6 Mice-A Pilot Study.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinoma; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pilot Projects | 2022 |
Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Lactobacillaceae; Metabolome; Mice; Mice, Inbred C57BL | 2022 |
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Kefir; Lactobacillus; Mice; RNA, Ribosomal, 16S; Saccharomyces cerevisiae; Tibet | 2022 |
Berberine inhibits intestinal carcinogenesis by suppressing intestinal pro-inflammatory genes and oncogenic factors through modulating gut microbiota.
Topics: Animals; Azoxymethane; Berberine; Carcinogenesis; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Mice; Mice, Inbred C57BL; NF-kappa B; RNA, Ribosomal, 16S | 2022 |
Supplementation with High or Low Iron Reduces Colitis Severity in an AOM/DSS Mouse Model.
Topics: Animals; Azoxymethane; Colitis; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Iron Overload; Iron, Dietary; Mice; Phosphatidylinositol 3-Kinases | 2022 |
Berberine regulates short-chain fatty acid metabolism and alleviates the colitis-associated colorectal tumorigenesis through remodeling intestinal flora.
Topics: Animals; Azoxymethane; Berberine; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Fatty Acids, Volatile; Gastrointestinal Microbiome; Interleukin-6; Lipopolysaccharides; Mice; Mice, Inbred C57BL; NF-kappa B; Occludin; Tandem Mass Spectrometry; Toll-Like Receptor 4 | 2022 |
A Biscuit Containing Fucoxanthin Prevents Colorectal Carcinogenesis in Mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Mice; Xanthophylls | 2022 |
Madecassic acid alleviates colitis-associated colorectal cancer by blocking the recruitment of myeloid-derived suppressor cells via the inhibition of IL-17 expression in γδT17 cells.
Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Interleukin-17; Mice; Mice, Inbred C57BL; Myeloid-Derived Suppressor Cells; Receptors, Antigen, T-Cell, gamma-delta; Signal Transduction; Th17 Cells; Triterpenes; Tumor Microenvironment | 2022 |
Ojeok-san ameliorates visceral and somatic nociception in a mouse model of colitis induced colorectal cancer.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Inbred C57BL; Nociception; Plant Extracts | 2022 |
Lacticaseibacillus rhamnosus LS8 Ameliorates Azoxymethane/Dextran Sulfate Sodium-Induced Colitis-Associated Tumorigenesis in Mice via Regulating Gut Microbiota and Inhibiting Inflammation.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Dextran Sulfate; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Lacticaseibacillus rhamnosus; Mice | 2022 |
MUC1-mediated Macrophage Activation Promotes Colitis-associated Colorectal Cancer via Activating the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Axis.
Topics: Animals; Azoxymethane; Carcinogenesis; Chemotactic Factors; Colitis; Colitis-Associated Neoplasms; Colonic Neoplasms; Dextran Sulfate; Interleukin-6; Macrophage Activation; Mice; Mice, Knockout; Mucin-1; STAT3 Transcription Factor | 2022 |
Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer.
Topics: Animals; Azoxymethane; Bacteroidetes; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Firmicutes; Humans; Inflammation; Mice; Mice, Inbred C57BL; Naphthoquinones; Tumor Microenvironment | 2022 |
Supplementation of polyphenol-rich grapes attenuates colitis, colitis-associated colon cancer, and disease-associated dysbiosis in mice, but fails to mitigate colitis in antibiotic-treated mice.
Topics: Animals; Anti-Bacterial Agents; Azoxymethane; Bacteria; Butyrates; Colitis; Colitis-Associated Neoplasms; Colon; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Dysbiosis; Mice; Mice, Inbred C57BL; Polyphenols; Powders; Vitis | 2022 |
Presume Why Probiotics May Not Provide Protection in Inflammatory Bowel Disease through an Azoxymethane and Dextran Sodium Sulfate Murine Model.
Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Dextran Sulfate; Disease Models, Animal; Dysbiosis; Inflammatory Bowel Diseases; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Probiotics; Sulfates | 2022 |
Colitis Induces Sex-Specific Intestinal Transcriptomic Responses in Mice.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Humans; Inflammation; Inflammatory Bowel Diseases; Male; Mice; Mice, Inbred C57BL; Receptors, Glucocorticoid; RNA; Transcriptome | 2022 |
Identification of natural product 3, 5-diiodotyrosine as APOBEC3B inhibitor to prevent somatic mutation accumulation and cancer progression.
Topics: Animals; Azoxymethane; B7-H1 Antigen; Biological Products; Colitis; Colonic Neoplasms; Diiodotyrosine; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Interleukin-15; Mice; Minor Histocompatibility Antigens; Mutation Accumulation; Programmed Cell Death 1 Receptor; Tumor Microenvironment | 2022 |
Rapamycin Liposomes Combined with 5-Fluorouracil Inhibits Angiogenesis and Tumor Growth of APC
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Fluorouracil; Lipopolysaccharides; Liposomes; Mice; Mice, Inbred C57BL; Sirolimus | 2022 |
CCL17 Promotes Colitis-Associated Tumorigenesis Dependent on the Microbiota.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Chemokine CCL17; Colitis; Colonic Neoplasms; Gastrointestinal Microbiome; Mice | 2022 |
Establishment of a Novel Colitis-Associated Cancer Mouse Model Showing Flat Invasive Neoplasia.
Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Dextrans; Disease Models, Animal; Humans; Inflammation; Mice; Reproducibility of Results | 2023 |
The HIF-prolyl hydroxylases have distinct and nonredundant roles in colitis-associated cancer.
Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Epithelial Cells; Mice; Prolyl Hydroxylases | 2022 |
Supplementation of quinoa peptides alleviates colorectal cancer and restores gut microbiota in AOM/DSS-treated mice.
Topics: Animals; Azoxymethane; Chenopodium quinoa; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Mice; Mice, Inbred C57BL; Peptides; Probiotics | 2023 |
Interleukin-34 deficiency aggravates development of colitis and colitis-associated cancer in mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colitis-Associated Neoplasms; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Interleukins; Mice | 2022 |
Ginsenoside Rb1 Suppresses AOM/DSS-induced Colon Carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colorectal Neoplasms; Disease Models, Animal; Ginsenosides; Inflammation; Mice; Mice, Inbred C57BL; Tumor Microenvironment | 2023 |
Boris knockout eliminates AOM/DSS-induced in situ colorectal cancer by suppressing DNA damage repair and inflammation.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; DNA Damage; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout | 2023 |
AC1Q3QWB inhibits colorectal cancer progression by modulating the immune response and balancing the structure of the intestinal microbiota.
Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Dimethyl Sulfoxide; Disease Models, Animal; Gastrointestinal Microbiome; Immunity; Mice; Mice, Inbred C57BL; RNA, Ribosomal, 16S | 2023 |
Myeloid FTH1 Deficiency Protects Mice From Colitis and Colitis-associated Colorectal Cancer via Reducing DMT1-Imported Iron and STAT3 Activation.
Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Iron; Mice; Mice, Inbred C57BL; STAT3 Transcription Factor | 2023 |
Sleep Fragmentation Accelerates Carcinogenesis in a Chemical-Induced Colon Cancer Model.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Sleep Deprivation | 2023 |
Combining gamma-tocopherol and aspirin synergistically suppresses colitis-associated colon tumorigenesis and modulates the gut microbiota in mice, and inhibits the growth of human colon cancer cells.
Topics: Animals; Aspirin; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; gamma-Tocopherol; Gastrointestinal Microbiome; Humans; Mice; Mice, Inbred C57BL | 2023 |
Role of Dietary Defatted Rice Bran in the Modulation of Gut Microbiota in AOM/DSS-Induced Colitis-Associated Colorectal Cancer Rat Model.
Topics: Animals; Azoxymethane; Bacteria; Bacteroidetes; Colitis; Colitis-Associated Neoplasms; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Mice; Mice, Inbred C57BL; Oryza; Rats | 2023 |
Geniposide prevents tumor growth by inhibiting colonic interleukin-1β and monocyte chemoattractant protein-1 via down-regulated expression of cyclooxygenase-2 and thymocyte selection-associated high mobility box proteins TOX/TOX2 in azoxymethane/dextran s
Topics: Animals; Azoxymethane; Chemokine CCL2; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Interleukin-10; Interleukin-1beta; Mice; Mice, Inbred C57BL; Programmed Cell Death 1 Receptor; Thymocytes | 2023 |
Inhibitory effects of
Topics: Animals; Azoxymethane; Clostridium butyricum; Colitis; Colorectal Neoplasms; Cytokines; Mice; Mice, Inbred C57BL | 2023 |
Zearalenone attenuates colitis associated colorectal tumorigenesis through Ras/Raf/ERK pathway suppression and SCFA-producing bacteria promotion.
Topics: Animals; Azoxymethane; Bacteria; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Humans; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Zearalenone | 2023 |
[Anemoside B4 regulates fatty acid metabolism reprogramming in mice with colitis-associated cancer].
Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Mice; Mice, Inbred C57BL; PPAR alpha; RNA, Messenger; Sterol Regulatory Element Binding Protein 1 | 2023 |
Panaxynol alleviates colorectal cancer in a murine model via suppressing macrophages and inflammation.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mucins | 2023 |
Anticancer Effects of Washed-Dehydrated Solar Salt Doenjang on Colon Cancer-Induced C57BL/6 Mice.
Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Inflammation; Interleukin-6; Mice; Mice, Inbred C57BL; Sodium Chloride, Dietary; Tumor Necrosis Factor-alpha | 2023 |
A Short-Term Model of Colitis-Associated Colorectal Cancer That Suggests Initial Tumor Development and the Characteristics of Cancer Stem Cells.
Topics: Animals; Azoxymethane; beta Catenin; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Humans; Ki-67 Antigen; Mice; Mice, Inbred C57BL; Neoplastic Stem Cells | 2023 |
ENPP2 inhibitor improves proliferation in AOM/DSS-induced colorectal cancer mice via remodeling the gut barrier function and gut microbiota composition.
Topics: Animals; Azoxymethane; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Mice; Mice, Inbred C57BL; Phosphoric Diester Hydrolases | 2023 |
Beneficial effects of alpha-1 antitrypsin therapy in a mouse model of colitis-associated colon cancer.
Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL | 2023 |
Astragaloside IV inhibits AOM/DSS-induced colitis-associated tumorigenesis via activation of PPARγ signaling in mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Dextran Sulfate; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; PPAR gamma; Reactive Oxygen Species | 2023 |
The effect of aerobic and resistance exercise on the progression of colorectal cancer in an animal model.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Resistance Training | 2023 |
Chemopreventive Effects of Polysaccharides and Flavonoids from Okra Flowers in Azomethane/Dextran Sulfate Sodium-Induced Murine Colitis-Associated Cancer.
Topics: Abelmoschus; Animals; Anticarcinogenic Agents; Azoxymethane; beta Catenin; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Flavonoids; Hominidae; Humans; Interleukin-6; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt | 2023 |
Helminth-derived molecules inhibit colitis-associated colon cancer development through NF-κB and STAT3 regulation.
Topics: Animals; Anti-Inflammatory Agents; Azoxymethane; Cell Proliferation; Cell Survival; Colitis; Colonic Neoplasms; Disease Models, Animal; Female; Helminth Proteins; Humans; Interleukin-1beta; Interleukin-33; Mice; NF-kappa B; Phosphorylation; Proto-Oncogene Mas; STAT3 Transcription Factor; Taenia; Tumor Necrosis Factor-alpha | 2019 |
Upregulation of PD-1 follows tumour development in the AOM/DSS model of inflammation-induced colorectal cancer in mice.
Topics: Animals; Azoxymethane; B7-H1 Antigen; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Intestinal Mucosa; Lymphocyte Activation; Mice, Inbred C57BL; Phenotype; Programmed Cell Death 1 Ligand 2 Protein; Programmed Cell Death 1 Receptor; Signal Transduction; T-Lymphocytes; Up-Regulation | 2019 |
Thermally Processed Oil Exaggerates Colonic Inflammation and Colitis-Associated Colon Tumorigenesis in Mice.
Topics: Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Hot Temperature; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; Oils | 2019 |
Differential expression of miRNAs regulating NF-κB and STAT3 crosstalk during colitis-associated tumorigenesis.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; MicroRNAs; NF-kappa B; Signal Transduction; STAT3 Transcription Factor | 2019 |
Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch.
Topics: Adenocarcinoma; Animals; Appendectomy; Azoxymethane; Carcinogens; Cecum; Chronic Disease; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Male; Mice, Inbred C57BL | 2019 |
Polysaccharides isolated from Nostoc commune Vaucher inhibit colitis-associated colon tumorigenesis in mice and modulate gut microbiota.
Topics: Animals; Azoxymethane; Bacteria; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Fatty Acids, Volatile; Feces; Gastrointestinal Microbiome; Male; Mice; Mice, Inbred C57BL; Nostoc commune; Polysaccharides; RNA, Ribosomal, 16S | 2019 |
Dietary Tricin Suppresses Inflammation-Related Colon Carcinogenesis in Mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Diet; Flavonoids; Male; Mice; Tumor Necrosis Factor-alpha | 2019 |
Identification of novel Nrf2 target genes as prognostic biomarkers in colitis-associated colorectal cancer in Nrf2-deficient mice.
Topics: Animals; Azoxymethane; Biomarkers; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Signal Transduction | 2019 |
Orally Deliverable Nanotherapeutics for the Synergistic Treatment of Colitis-Associated Colorectal Cancer.
Topics: Administration, Oral; Animals; Apoptosis; Azoxymethane; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colitis; Colorectal Neoplasms; Curcumin; Cytokines; Dextran Sulfate; Disease Models, Animal; Disease Progression; Drug Synergism; Female; Inflammation; Inflammation Mediators; Intestines; Irinotecan; Macrophages; Mice; Mice, Inbred C57BL; Nanoparticles; RAW 264.7 Cells | 2019 |
Toll-like Receptor-6 Signaling Prevents Inflammation and Impacts Composition of the Microbiota During Inflammation-Induced Colorectal Cancer.
Topics: Animals; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Female; Gastrointestinal Microbiome; Humans; Immunity, Innate; Interleukin-10; Intestinal Mucosa; Lactobacillus; Mice; Mice, Knockout; Neoplasms, Experimental; Probiotics; Proteobacteria; Recombinant Proteins; Signal Transduction; Toll-Like Receptor 6 | 2020 |
Temporal DNA methylation pattern and targeted therapy in colitis-associated cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Azoxymethane; bcl-Associated Death Protein; Carcinogenesis; Cell Line, Tumor; Colitis; Colon; Colonoscopy; Colorectal Neoplasms; Decitabine; Disease Models, Animal; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Male; Mice; Molecular Targeted Therapy; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Up-Regulation | 2020 |
Role of transient receptor potential vanilloid subtype 4 in the regulation of azoymethane/dextran sulphate sodium-induced colitis-associated cancer in mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Cell Proliferation; Chemokine CXCL2; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Progression; Human Umbilical Vein Endothelial Cells; Humans; Intestinal Mucosa; Macrophages; Male; Mice; Mice, Knockout; Neoplasms, Experimental; TRPV Cation Channels | 2020 |
The impact of gut microbiota manipulation with antibiotics on colon tumorigenesis in a murine model.
Topics: Animals; Anti-Bacterial Agents; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Microbiome; High-Throughput Nucleotide Sequencing; Inflammation; Mice; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Tumor Burden | 2019 |
Switching to a Healthy Diet Prevents the Detrimental Effects of Western Diet in a Colitis-Associated Colorectal Cancer Model.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Diet, Healthy; Diet, Western; Disease Models, Animal; Female; Gastrointestinal Microbiome; Liver; Mice; Mice, Inbred BALB C; Vitamin D | 2019 |
Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation.
Topics: Adaptor Proteins, Signal Transducing; Adenomatous Polyposis Coli; Animals; Azoxymethane; Carcinogenesis; Cell Adhesion Molecules; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Focal Adhesion Protein-Tyrosine Kinases; Humans; Inflammation; Integrins; Interleukin-6; Intestines; Mice, Inbred C57BL; Myofibroblasts; Precancerous Conditions; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Stromal Cells; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins | 2020 |
Affective state determination in a mouse model of colitis-associated colorectal cancer.
Topics: Animals; Azoxymethane; Behavior; Buprenorphine; Colitis; Colonoscopy; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Mice; Mice, Inbred C57BL; Pain Measurement; Retrospective Studies; Risk Assessment | 2020 |
Reduction of colitis-associated colon carcinogenesis by a black lentil water extract through inhibition of inflammatory and immunomodulatory cytokines.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Fabaceae; Gene Expression Profiling; Inflammation; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Water | 2020 |
Protective Effects of Zerumbone on Colonic Tumorigenesis in Enterotoxigenic
Topics: Administration, Oral; Animals; Azoxymethane; Bacteroides fragilis; Body Weight; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Female; Mice; Mice, Inbred BALB C; Protective Agents; Sesquiterpenes; Severity of Illness Index | 2020 |
Consumption of the Total Western Diet Promotes Colitis and Inflammation-Associated Colorectal Cancer in Mice.
Topics: Adaptive Immunity; Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Diet, Western; Disease Models, Animal; Immunity, Innate; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; RNA, Messenger | 2020 |
Inhibitory Effects of Bound Polyphenol from Foxtail Millet Bran on Colitis-Associated Carcinogenesis by the Restoration of Gut Microbiota in a Mice Model.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colorectal Neoplasms; Dextran Sulfate; Ecosystem; Gastrointestinal Microbiome; Mice; Mice, Nude; Polyphenols; RNA, Ribosomal, 16S; Setaria Plant | 2020 |
CD30L/CD30 signaling regulates the formation of the tumor immune microenvironment and inhibits intestinal tumor development of colitis-associated colon cancer in mice.
Topics: Animals; Azoxymethane; Carcinogens; CD30 Ligand; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Colitis; Colitis-Associated Neoplasms; Dextran Sulfate; Female; Intestines; Ki-1 Antigen; Male; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction; Tumor Microenvironment | 2020 |
Aspirin Reduces Colorectal Tumor Development in Mice and Gut Microbes Reduce its Bioavailability and Chemopreventive Effects.
Topics: Adenomatous Polyposis Coli Protein; Animals; Anti-Bacterial Agents; Anticarcinogenic Agents; Aspirin; Azoxymethane; Bacillaceae; Bacteroides fragilis; Bacteroidetes; Biological Availability; Carcinogenesis; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; DNA, Bacterial; Dose-Response Relationship, Drug; Feces; Gastrointestinal Microbiome; Germ-Free Life; Humans; Intestinal Mucosa; Male; Mice; Mice, Transgenic; RNA, Ribosomal, 16S | 2020 |
A Nucleotide Analog Prevents Colitis-Associated Cancer via Beta-Catenin Independently of Inflammation and Autophagy.
Topics: Administration, Rectal; Animals; Autophagy; Autophagy-Related Protein 7; Azoxymethane; beta Catenin; Caco-2 Cells; Colitis; Colitis-Associated Neoplasms; Colon; Dextran Sulfate; Gene Knockdown Techniques; HCT116 Cells; Humans; Intestinal Mucosa; Mercaptopurine; Mice; Mice, Transgenic; Neuropeptides; rac1 GTP-Binding Protein; Thioguanine; Wnt Signaling Pathway | 2021 |
Apple polysaccharide prevents from colitis-associated carcinogenesis through regulating macrophage polarization.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Macrophages; Male; Malus; Mice; Mice, Inbred ICR; Polysaccharides; RAW 264.7 Cells; Signal Transduction; Toll-Like Receptor 4 | 2020 |
Clostridium butyricum modulates gut microbiota and reduces colitis associated colon cancer in mice.
Topics: Animals; Apoptosis; Azoxymethane; Bacteroidetes; Body Weight; Cell Proliferation; Clostridium butyricum; Colitis; Colitis-Associated Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Feces; Firmicutes; Gastrointestinal Microbiome; Inflammation; Male; Mice, Inbred C57BL; NF-kappa B p50 Subunit; RNA, Ribosomal, 16S | 2020 |
Effects of triptolide on the sphingosine kinase - Sphingosine-1-phosphate signaling pathway in colitis-associated colon cancer.
Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colon; Dextran Sulfate; Disease Models, Animal; Diterpenes; Epoxy Compounds; Female; Humans; Lysophospholipids; Male; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Phenanthrenes; Phosphotransferases (Alcohol Group Acceptor); Signal Transduction; Sphingosine; THP-1 Cells; Tumor-Associated Macrophages | 2020 |
ARC Is a Critical Protector against Inflammatory Bowel Disease (IBD) and IBD-Associated Colorectal Tumorigenesis.
Topics: Animals; Apoptosis Regulatory Proteins; Azoxymethane; Bone Marrow Transplantation; CD4-Positive T-Lymphocytes; Chemokine CCL5; Chemokine CXCL5; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Humans; Inflammatory Bowel Diseases; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Male; Mice, Inbred C57BL; Mice, Knockout; Muscle Proteins; Ubiquitination | 2020 |
Cyclic derivative of morphiceptin Dmt-cyclo-(D-Lys-Phe-D-Pro-Asp)-NH2(P-317), a mixed agonist of MOP and KOP opioid receptors, exerts anti-inflammatory and anti-tumor activity in colitis and colitis-associated colorectal cancer in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Azoxymethane; Carcinogens; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Endorphins; Male; Mice; Mice, Inbred BALB C; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tumor Necrosis Factor-alpha | 2020 |
Toll-like receptor 4 prevents AOM/DSS-induced colitis-associated colorectal cancer in Bacteroides fragilis gnotobiotic mice.
Topics: Animals; Azoxymethane; Bacteroides fragilis; beta Catenin; Colitis; Colitis-Associated Neoplasms; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Disease Models, Animal; Germ-Free Life; Male; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type II; Proliferating Cell Nuclear Antigen; Toll-Like Receptor 4 | 2021 |
The Interplay Between Innate Immunity (TLR-4) and sCD40L in the Context of an Animal Model of Colitis-associated Cancer.
Topics: Animals; Azoxymethane; CD40 Ligand; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Immunity, Innate; Mice; Mice, Knockout; Toll-Like Receptor 4 | 2020 |
Stroma-derived ANGPTL2 establishes an anti-tumor microenvironment during intestinal tumorigenesis.
Topics: Angiopoietin-Like Protein 2; Angiopoietin-like Proteins; Animals; Azoxymethane; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Colitis; Dextran Sulfate; Disease Models, Animal; Gene Knockout Techniques; Intestinal Neoplasms; Macrophages; Mice; NF-kappa B; Signal Transduction; Tumor Microenvironment | 2021 |
A thermogenic fat-epithelium cell axis regulates intestinal disease tolerance.
Topics: Adipocytes; Adipose Tissue, Brown; Animals; Azoxymethane; Cell Communication; Citrobacter rodentium; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Resistance; Enterobacteriaceae Infections; Epithelial Cells; Female; Humans; Intestinal Mucosa; Male; Mice; Neoplasms, Experimental; Thermogenesis | 2020 |
The Glucocorticoid Receptor in Intestinal Epithelial Cells Alleviates Colitis and Associated Colorectal Cancer in Mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colitis-Associated Neoplasms; Dextran Sulfate; Female; Gene Expression Profiling; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Knockout; Permeability; Receptors, Glucocorticoid | 2021 |
Vitamin E delta-tocotrienol and metabolite 13'-carboxychromanol inhibit colitis-associated colon tumorigenesis and modulate gut microbiota in mice.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Benzopyrans; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Fatty Acids; Feces; Gastrointestinal Microbiome; Humans; Inflammation; Interleukin-1beta; Male; Mice; Mice, Inbred BALB C; RNA, Ribosomal, 16S; Vitamin E | 2021 |
Colonic Epithelial-Derived Selenoprotein P Is the Source for Antioxidant-Mediated Protection in Colitis-Associated Cancer.
Topics: Adolescent; Animals; Azoxymethane; Case-Control Studies; Cell Transformation, Neoplastic; Child; Child, Preschool; Colitis; Colitis-Associated Neoplasms; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; DNA Damage; Female; Genomic Instability; Humans; Intestinal Mucosa; Liver; Male; Mice, Knockout; Myeloid Cells; Oxidative Stress; Selenoprotein P | 2021 |
Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis.
Topics: Acrolein; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred A; RNA-Binding Proteins | 2021 |
Glutathione transferase Omega 1 confers protection against azoxymethane-induced colorectal tumour formation.
Topics: Animals; Azoxymethane; Carcinogens; Carrier Proteins; Colitis; Colorectal Neoplasms; Dextran Sulfate; Glutathione Transferase; Inflammation; Interleukin-18; Interleukin-1beta; Mice; Mice, Inbred C57BL; Mice, Knockout | 2021 |
Vitexin prevents colitis-associated carcinogenesis in mice through regulating macrophage polarization.
Topics: Animals; Anticarcinogenic Agents; Apigenin; Azoxymethane; Carcinogenesis; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Inflammatory Bowel Diseases; Macrophages; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III | 2021 |
Induction of colitis-associated neoplasia in mice using azoxymethane and dextran sodium sulfate.
Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Mice; Mice, Inbred C57BL; Sulfates | 2021 |
Shinan Sea Salt Intake Ameliorates Colorectal Cancer in AOM/DSS with High Fat Diet-Induced C57BL/6N Mice.
Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Diet, High-Fat; Mice; Mice, Inbred C57BL; Republic of Korea; Sodium Chloride, Dietary | 2021 |
Cardamonin Attenuates Experimental Colitis and Associated Colorectal Cancer.
Topics: Animals; Anti-Inflammatory Agents; Azoxymethane; Cell Proliferation; Cell Survival; Chalcones; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Mice; MicroRNAs; Nitrous Oxide; RAW 264.7 Cells; Sequence Analysis, RNA; Signal Transduction; THP-1 Cells | 2021 |
Alisol B 23-Acetate Ameliorates Azoxymethane/Dextran Sodium Sulfate-Induced Male Murine Colitis-Associated Colorectal Cancer
Topics: Animals; Azoxymethane; China; Cholestenones; Colitis; Colitis-Associated Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Male; Mice; Mice, Inbred C57BL; Sulfates | 2021 |
Galectin-1 fosters an immunosuppressive microenvironment in colorectal cancer by reprogramming CD8
Topics: Adenocarcinoma; Animals; Atlases as Topic; Azoxymethane; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Colitis; Colorectal Neoplasms; Computational Biology; Dextran Sulfate; Disease Models, Animal; Galectin 1; Gene Expression Regulation, Neoplastic; Humans; Interleukin-2 Receptor beta Subunit; Mice; Mice, Knockout; Programmed Cell Death 1 Receptor; Signal Transduction; Survival Analysis; T-Lymphocytes, Regulatory; Tumor Burden | 2021 |
Aspirin inhibits prostaglandins to prevents colon tumor formation via down-regulating Wnt production.
Topics: Animals; Aspirin; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colitis-Associated Neoplasms; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Down-Regulation; Humans; Male; Mice; Nuclear Receptor Subfamily 4, Group A, Member 2; Proteomics; Proto-Oncogene Proteins; Wnt Proteins; Wnt Signaling Pathway | 2021 |
Transcriptome analysis of potential candidate genes and molecular pathways in colitis-associated colorectal cancer of Mkp-1-deficient mice.
Topics: Animals; Azoxymethane; Biomarkers, Tumor; Carcinogenesis; Colitis; Colitis-Associated Neoplasms; Computational Biology; Dextran Sulfate; Disease Models, Animal; Dual Specificity Phosphatase 1; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Knockout; Prognosis; Protein Interaction Mapping; Protein Interaction Maps; RNA-Seq; Signal Transduction | 2021 |
A synthetic probiotic engineered for colorectal cancer therapy modulates gut microbiota.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Mice; Mice, Inbred C57BL; Probiotics | 2021 |
Phaseolin, a Protein from the Seed of
Topics: Aberrant Crypt Foci; Animals; Antioxidants; Azoxymethane; Chemical and Drug Induced Liver Injury; Chemoprevention; Colitis; Colon; Disease Models, Animal; DNA Damage; Male; Mice; Oxidation-Reduction; Oxidative Stress; Phaseolus; Plant Extracts; Protective Agents; Seeds | 2021 |
Ganoderma lucidum polysaccharide modulates gut microbiota and immune cell function to inhibit inflammation and tumorigenesis in colon.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Dysbiosis; Fungal Polysaccharides; Gastrointestinal Microbiome; Humans; Inflammation; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; RAW 264.7 Cells; Reishi; Signal Transduction | 2021 |
Lactobacillus coryniformis MXJ32 administration ameliorates azoxymethane/dextran sulfate sodium-induced colitis-associated colorectal cancer via reshaping intestinal microenvironment and alleviating inflammatory response.
Topics: Animals; Azoxymethane; Colitis; Colitis-Associated Neoplasms; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Lactobacillus; Mice; Mice, Inbred C57BL; Probiotics; Tumor Microenvironment | 2022 |
Inhibitory Effect of Garcinol on Obesity-Exacerbated, Colitis-Mediated Colon Carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Biomarkers; Cell Proliferation; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Diet, High-Fat; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Gene Expression Regulation, Neoplastic; Lipids; Male; Mice, Inbred C57BL; Obesity; Organ Size; Proliferating Cell Nuclear Antigen; Terpenes | 2021 |
Lack of STAT6 Attenuates Inflammation and Drives Protection against Early Steps of Colitis-Associated Colon Cancer.
Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Cell Proliferation; Colitis; Colon; Colonic Neoplasms; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Female; Inflammation; Mice, Inbred BALB C; Mice, Knockout; RNA, Messenger; STAT6 Transcription Factor | 2017 |
EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients.
Topics: Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Epithelial Cells; ErbB Receptors; Humans; Inhibitor of Apoptosis Proteins; Interleukin-6; Intestinal Mucosa; Kaplan-Meier Estimate; Mice; Myeloid Cells; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Repressor Proteins; Signal Transduction; STAT3 Transcription Factor; Survival Rate; Survivin; Tumor Burden | 2017 |
Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer.
Topics: Animals; Azoxymethane; beta Catenin; Body Weight; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Disease Models, Animal; Mice; Receptors, Leukotriene | 2017 |
Expression of A-kinase anchor protein 13 and Rho-associated coiled-coil containing protein kinase in restituted and regenerated mucosal epithelial cells following mucosal injury and colorectal cancer cells in mouse models.
Topics: A Kinase Anchor Proteins; Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Guanine Nucleotide Exchange Factors; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Minor Histocompatibility Antigens; Regeneration; rho-Associated Kinases; Wound Healing | 2017 |
Sildenafil Suppresses Inflammation-Driven Colorectal Cancer in Mice.
Topics: Administration, Oral; Animals; Apoptosis; Azoxymethane; Carcinogenesis; Colitis; Colon; Colorectal Neoplasms; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dextran Sulfate; Humans; Immunohistochemistry; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Phosphodiesterase 5 Inhibitors; Polyps; Signal Transduction; Sildenafil Citrate | 2017 |
Clostridium butyricum partially regulates the development of colitis-associated cancer through miR-200c.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Clostridium butyricum; Colitis; Colonic Neoplasms; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization, Fluorescence; Inflammation; Interleukin-12; Mice; MicroRNAs; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2017 |
E-cadherin Mediates the Preventive Effect of Vitamin D3 in Colitis-associated Carcinogenesis.
Topics: Animals; Azoxymethane; beta Catenin; Cadherins; Carcinogenesis; Cell Proliferation; Cholecalciferol; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Up-Regulation; Vitamins | 2017 |
Role of intestinal microbiome in American ginseng-mediated colon cancer prevention in high fat diet-fed AOM/DSS mice [corrected].
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Diet, High-Fat; Gastrointestinal Microbiome; Male; Mice; Panax; Plant Extracts; Plant Roots | 2018 |
Dietary Phenethyl Isothiocyanate Protects Mice from Colitis Associated Colon Cancer.
Topics: Animals; Azoxymethane; Blotting, Western; Cell Survival; Chromatin Immunoprecipitation; Colitis; Colonic Neoplasms; Dextran Sulfate; Dietary Supplements; Humans; Isothiocyanates; Male; Mice; Mice, Inbred C57BL; NF-kappa B; RAW 264.7 Cells | 2017 |
Dietary Peptides from Phaseolus vulgaris L. Reduced AOM/DSS-Induced Colitis-Associated Colon Carcinogenesis in Balb/c Mice.
Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Dextran Sulfate; Dietary Proteins; Mice, Inbred BALB C; Phaseolus; Plant Extracts | 2017 |
IL-17A-Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Cells, Cultured; Clustered Regularly Interspaced Short Palindromic Repeats; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Epithelial Cells; Gene Expression Regulation, Neoplastic; Interleukin-17; Mice; Mice, Inbred C57BL; Mice, Knockout; Pregnancy Proteins; Receptors, Interleukin; Wound Healing | 2017 |
Inhibition of MK2 suppresses IL-1β, IL-6, and TNF-α-dependent colorectal cancer growth.
Topics: Animals; Azoxymethane; Cell Line, Tumor; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Female; Inflammation; Interleukin-1beta; Interleukin-6; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Protein Serine-Threonine Kinases; Signal Transduction; Tumor Necrosis Factor-alpha | 2018 |
Small molecules related to adrenomedullin reduce tumor burden in a mouse model of colitis-associated colon cancer.
Topics: Adrenomedullin; Animals; Antineoplastic Agents; Azoxymethane; Cluster Analysis; Colitis; Colon; Colonic Neoplasms; Disease Models, Animal; Disease Progression; Gastrointestinal Agents; Mice | 2017 |
Pretreatment with probiotic Bifico ameliorates colitis-associated cancer in mice: Transcriptome and gut flora profiling.
Topics: Administration, Oral; Animals; Azoxymethane; Bacteria; Chemokines, CXC; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Gene Expression Profiling; Humans; Male; Mice; Mice, Inbred C57BL; Probiotics; RNA, Ribosomal, 16S; Signal Transduction; Xenograft Model Antitumor Assays | 2018 |
Elevated d-2-hydroxyglutarate during colitis drives progression to colorectal cancer.
Topics: Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Biopsy; Caco-2 Cells; Cell Movement; Cell Proliferation; Cell Survival; Colitis; Colitis, Ulcerative; Colorectal Neoplasms; Dextran Sulfate; Disease Progression; Glutarates; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Intestinal Mucosa; Mice; Risk | 2018 |
Chemopreventive Effect of Aster glehni on Inflammation-Induced Colorectal Carcinogenesis in Mice.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Aster Plant; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dextran Sulfate; Inflammation; Interleukins; Male; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Spleen; Tumor Necrosis Factor-alpha | 2018 |
Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colitis; Colonic Neoplasms; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dextran Sulfate; Disease Progression; Epigenesis, Genetic; Histone Deacetylases; Homeostasis; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Neutrophils; Receptors, G-Protein-Coupled | 2018 |
DNA methylome and transcriptome alterations and cancer prevention by curcumin in colitis-accelerated colon cancer in mice.
Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Curcumin; Dextran Sulfate; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Inflammation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Transcriptome | 2018 |
Natural dietary compound naringin prevents azoxymethane/dextran sodium sulfate-induced chronic colorectal inflammation and carcinogenesis in mice.
Topics: Animals; Autophagy; Azoxymethane; Biomarkers; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cytokines; Dietary Supplements; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Flavanones; Inflammation Mediators; Intestinal Mucosa; Male; Mice; Sulfates | 2018 |
1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogens; Cdc20 Proteins; Cell Cycle; Cell Proliferation; Colitis; Colonic Neoplasms; Enzyme Inhibitors; Homeodomain Proteins; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitosis; Tryptophan; Tumor Cells, Cultured | 2018 |
Pristimerin, a naturally occurring triterpenoid, attenuates tumorigenesis in experimental colitis-associated colon cancer.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Apoptosis; Azoxymethane; Cell Cycle; Cell Proliferation; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Female; Forkhead Box Protein O3; Mice, Inbred BALB C; NF-kappa B; Pentacyclic Triterpenes; Proto-Oncogene Proteins c-akt; Triterpenes | 2018 |
Tea Polysaccharides Inhibit Colitis-Associated Colorectal Cancer via Interleukin-6/STAT3 Pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Azoxymethane; Camellia sinensis; Cell Line, Tumor; Colitis; Colorectal Neoplasms; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Inflammation; Interleukin-6; Macrophages; Mice; Mice, Inbred BALB C; Polysaccharides; RAW 264.7 Cells; Signal Transduction; STAT3 Transcription Factor; Tea | 2018 |
Prolyl hydroxylase 2 is dispensable for homeostasis of intestinal epithelium in mice.
Topics: Animals; Azoxymethane; Cell Line; Cell Line, Tumor; Colitis; Colonic Neoplasms; Dextran Sulfate; Epithelial Cells; Homeostasis; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; Intestinal Mucosa; Mice, Knockout; Mice, Transgenic | 2018 |
Short-chain fatty acids administration is protective in colitis-associated colorectal cancer development.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cecum; Cell Proliferation; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Fatty Acids, Volatile; Male; Mice, Inbred BALB C; NF-kappa B; Receptors, G-Protein-Coupled | 2018 |
Microbiota modification by probiotic supplementation reduces colitis associated colon cancer in mice.
Topics: Animals; Azoxymethane; Bifidobacterium; Colitis; Colon; Colonic Neoplasms; Cytokines; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Lacticaseibacillus rhamnosus; Lactobacillus acidophilus; Male; Mice; Mice, Inbred C57BL; Probiotics; RNA, Ribosomal, 16S | 2018 |
Tumor Necrosis Factor Ligand-Related Molecule 1A Regulates the Occurrence of Colitis-Associated Colorectal Cancer.
Topics: Animals; Azoxymethane; beta Catenin; Cell Movement; Cell Proliferation; Colitis; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Invasiveness; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myc; Time Factors; Tumor Necrosis Factor Ligand Superfamily Member 15; Wnt Signaling Pathway | 2018 |
A Novel Modification of the AOM/DSS Model for Inducing Intestinal Adenomas in Mice.
Topics: Adenoma; Animals; Azoxymethane; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Humans; Intestinal Neoplasms; Mice, Inbred C57BL | 2018 |
Dro1/Ccdc80 inactivation promotes AOM/DSS-induced colorectal carcinogenesis and aggravates colitis by DSS in mice.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Epithelial-Mesenchymal Transition; Extracellular Matrix Proteins; Genes, Tumor Suppressor; Glycoproteins; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout | 2018 |
Pharmacological activation of epidermal growth factor receptor signaling inhibits colitis-associated cancer in mice.
Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Dextran Sulfate; Epidermal Growth Factor; ErbB Receptors; Mice; Neoplasm Proteins; Neoplasms, Experimental; Signal Transduction | 2018 |
HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice.
Topics: Animals; Antigens, Ly; ATP-Binding Cassette Transporters; Azoxymethane; Basic Helix-Loop-Helix Transcription Factors; Carcinogenesis; CD11b Antigen; Colitis; Colon; Dextran Sulfate; Disease Progression; Disease Susceptibility; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Knockout; Myeloid Cells; Promoter Regions, Genetic; Tumor Necrosis Factor-alpha; Von Hippel-Lindau Tumor Suppressor Protein | 2018 |
The Rac1 splice form Rac1b favors mouse colonic mucosa regeneration and contributes to intestinal cancer progression.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Progression; Epithelial Cells; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Neuropeptides; rac1 GTP-Binding Protein; Signal Transduction | 2018 |
MicroRNA‑449a is a potential predictor of colitis‑associated colorectal cancer progression.
Topics: Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Carcinogens; Case-Control Studies; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Progression; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Prognosis; Receptor, Notch1; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2018 |
Deletion of cadherin-17 enhances intestinal permeability and susceptibility to intestinal tumour formation.
Topics: Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Adenoma; Animals; Azoxymethane; Cadherins; Carcinoma; Cell Cycle Proteins; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Deletion; Genetic Predisposition to Disease; Intestinal Absorption; Intestinal Mucosa; Mice, Inbred C57BL; Mice, Knockout; Permeability; Phenotype; Phosphoproteins; Signal Transduction; Tumor Suppressor Proteins; YAP-Signaling Proteins | 2018 |
Chemoprevention of inflammation-related colorectal cancer by silymarin-, acetyl-11-keto-beta-boswellic acid-, curcumin- and maltodextrin-enriched dietetic formulation in animal model.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Azoxymethane; Chemoprevention; Colitis; Colon; Colonoscopy; Colorectal Neoplasms; Curcumin; Cytokines; Dextran Sulfate; Disease Models, Animal; Food, Fortified; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Polysaccharides; Real-Time Polymerase Chain Reaction; Receptors, Estrogen; Silymarin; Triterpenes | 2018 |
DNA damage response genes mark the early transition from colitis to neoplasia in colitis-associated colon cancer.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Progression; DNA Damage; Gene Expression Regulation; Inflammation; Inflammatory Bowel Diseases; Intestines; Male; Mice; Mice, Inbred C57BL; Microsatellite Instability; Signal Transduction | 2018 |
TRIM27 mediates STAT3 activation at retromer-positive structures to promote colitis and colitis-associated carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Cell Transformation, Neoplastic; Colitis; Dextran Sulfate; DNA-Binding Proteins; HEK293 Cells; HeLa Cells; HT29 Cells; Humans; Interleukin-6; Mice; Nuclear Proteins; Signal Transduction; STAT3 Transcription Factor; Ubiquitin-Protein Ligases | 2018 |
Comprehensive analysis of differential circular RNA expression in a mouse model of colitis-induced colon carcinoma.
Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; MAP Kinase Signaling System; Mice; MicroRNAs; RNA; RNA, Circular | 2018 |
Matricellular protein periostin promotes colitis-associated colon tumorigenesis in mice.
Topics: Animals; Apoptosis; Azoxymethane; Caspase 3; Cell Adhesion Molecules; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cytokines; HCT116 Cells; Humans; Male; Mice; Mice, Inbred C57BL; NF-kappa B | 2019 |
The phosphatidic acid phosphatase lipin-1 facilitates inflammation-driven colon carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Chemokine CXCL1; Chemokine CXCL2; Colitis; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Humans; Inflammation; Inflammatory Bowel Diseases; Interleukin-23; Macrophages; Mice; Mice, Inbred BALB C; Mucous Membrane; Nuclear Proteins; Phosphatidate Phosphatase | 2018 |
Dietary Supplementation of Selenoneine-Containing Tuna Dark Muscle Extract Effectively Reduces Pathology of Experimental Colorectal Cancers in Mice.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Colitis; Colorectal Neoplasms; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Histidine; Mice; Muscles; Organoselenium Compounds; Spleen; Tuna | 2018 |
Chemopreventive Effects of Whole Cranberry (Vaccinium macrocarpon) on Colitis-Associated Colon Tumorigenesis.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Cell Proliferation; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Enzymes; Male; Mice, Inbred Strains; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Vaccinium macrocarpon | 2018 |
Single probiotic supplement suppresses colitis-associated colorectal tumorigenesis by modulating inflammatory development and microbial homeostasis.
Topics: Animals; Apoptosis; Azoxymethane; Caco-2 Cells; Cell Proliferation; Coculture Techniques; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Dysbiosis; Gastrointestinal Microbiome; Humans; Inflammation Mediators; Intestines; Lactobacillus helveticus; Male; Mice; Mice, Inbred C57BL; Probiotics; RAW 264.7 Cells; T-Lymphocytes | 2019 |
Effects of 17β-Estradiol on Colonic Permeability and Inflammation in an Azoxymethane/Dextran Sulfate Sodium-Induced Colitis Mouse Model.
Topics: Animals; Azoxymethane; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Estradiol; Inflammation; Intestinal Mucosa; Kruppel-Like Factor 4; Male; Mice; Mucin-2; Permeability; Signal Transduction; Tight Junctions | 2018 |
Therapeutic effects of lentinan on inflammatory bowel disease and colitis-associated cancer.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Azoxymethane; Carcinoembryonic Antigen; CD30 Ligand; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Microbiome; Gene Expression Regulation, Neoplastic; Hyperplasia; Interleukin-13; Keratin-18; Keratin-8; Lentinan; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NF-kappa B; Signal Transduction; Sulfasalazine; Toll-Like Receptor 4; Tumor Suppressor Protein p53 | 2019 |
Chemopreventive Effects of Silibinin on Colitis-Associated Tumorigenesis by Inhibiting IL-6/STAT3 Signaling Pathway.
Topics: Animals; Azoxymethane; Blotting, Western; Colitis; Colonic Neoplasms; Dextran Sulfate; Female; HCT116 Cells; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-6; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Silybin; STAT3 Transcription Factor | 2018 |
Tenascin-C Produced by Intestinal Myofibroblasts Promotes Colitis-associated Cancer Development Through Angiogenesis.
Topics: Animals; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Gene Expression Profiling; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Myofibroblasts; Neovascularization, Pathologic; Tenascin | 2019 |
Intermittent hypoxia promotes carcinogenesis in azoxymethane and dextran sodium sulfate-induced colon cancer model.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Hypoxia; Inflammation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress | 2019 |
Silibinin Retards Colitis-associated Carcinogenesis by Repression of Cdc25C in Mouse Model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Azoxymethane; Carcinogenesis; Carcinogens; cdc25 Phosphatases; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Inbred C57BL; Silybin | 2019 |
The Azoxymethane/Il10
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Disease Models, Animal; Germ-Free Life; Inflammation; Inflammatory Bowel Diseases; Interleukin-10; Intestines; Mice, Knockout | 2019 |
Impact of 5 fluorouracil chemotherapy on gut inflammation, functional parameters, and gut microbiota.
Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Fecal Microbiota Transplantation; Fluorouracil; Gastrointestinal Microbiome; Inflammation; Male; Mice; Mice, Inbred C57BL | 2019 |
Chemopreventive Activity of Red Ginseng Oil in a Mouse Model of Azoxymethane/Dextran Sulfate Sodium-Induced Inflammation-Associated Colon Carcinogenesis.
Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Disease Models, Animal; Humans; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Panax; Plant Extracts; Tumor Necrosis Factor-alpha | 2019 |
Cancer testis antigen 55 deficiency attenuates colitis-associated colorectal cancer by inhibiting NF-κB signaling.
Topics: Animals; Antigens, Neoplasm; Azoxymethane; Carcinogenesis; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; HCT116 Cells; HEK293 Cells; Humans; I-kappa B Kinase; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; NF-kappa B; Phosphorylation; Signal Transduction; Tumor Necrosis Factor-alpha | 2019 |
IL-21 Enhances the Development of Colitis-Associated Colon Cancer: Possible Involvement of Activation-Induced Cytidine Deaminase Expression.
Topics: Animals; Azoxymethane; B-Lymphocytes; Cell Line, Tumor; Colitis; Colonic Neoplasms; Cytidine Deaminase; Dextran Sulfate; Disease Models, Animal; Humans; Immunoglobulin Class Switching; Inflammatory Bowel Diseases; Interleukins; Intestinal Mucosa; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Transgenic | 2019 |
Platelet Depletion/Transfusion as a Lethal Factor in a Colitis-associated Cancer Mouse Model.
Topics: Animals; Azoxymethane; Blood Platelets; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Mice; Mice, Knockout; Platelet Transfusion; Toll-Like Receptor 4 | 2019 |
The diagnostic efficacy of circulating miRNAs in monitoring the early development of colitis-induced colorectal cancer.
Topics: Animals; Azoxymethane; Circulating MicroRNA; Colitis; Colorectal Neoplasms; Dextran Sulfate; Gene Expression Regulation, Neoplastic; Male; Mice; Neoplasms, Experimental | 2019 |
Peptide TNIIIA2 Derived from Tenascin-C Contributes to Malignant Progression in Colitis-Associated Colorectal Cancer via β1-Integrin Activation in Fibroblasts.
Topics: Animals; Azoxymethane; Caco-2 Cells; Cell Proliferation; Colitis; Colonic Polyps; Colorectal Neoplasms; Culture Media, Conditioned; Dextran Sulfate; Disease Models, Animal; Disease Progression; Epithelial Cells; Fibroblasts; Humans; Integrin beta1; Male; Mice, Inbred ICR; Paracrine Communication; Peptides; Tenascin | 2019 |
Ilexgenin A prevents early colonic carcinogenesis and reprogramed lipid metabolism through HIF1α/SREBP-1.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; beta Catenin; Colitis; Colorectal Neoplasms; Dextran Sulfate; HCT116 Cells; HT29 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lipid Metabolism; Male; Mice, Inbred BALB C; Sterol Regulatory Element Binding Protein 1; Triterpenes; Tumor Necrosis Factor-alpha | 2019 |
Oestrogens promote tumorigenesis in a mouse model for colitis-associated cancer.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Estradiol; Estrogens; Female; Hormone Replacement Therapy; Immunohistochemistry; Medroxyprogesterone; Mice; Ovariectomy | 2014 |
Inhibitory role of Gas6 in intestinal tumorigenesis.
Topics: Aged; Aged, 80 and over; Animals; Azoxymethane; Bone Marrow; Bone Marrow Transplantation; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Progression; Female; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Intercellular Signaling Peptides and Proteins; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Monocytes; NF-kappa B; Prognosis; Recombinant Proteins; RNA, Messenger; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins | 2013 |
Chemopreventive effect of dietary glutamine on colitis-associated colon tumorigenesis in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azoxymethane; Biomarkers, Tumor; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Colitis; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Dietary Supplements; Enzyme-Linked Immunosorbent Assay; Female; Glutamine; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide Synthase Type II; Real-Time Polymerase Chain Reaction; Rectum; Severity of Illness Index | 2013 |
Altered gut microbiota promotes colitis-associated cancer in IL-1 receptor-associated kinase M-deficient mice.
Topics: Animals; Azoxymethane; Blotting, Western; Carcinogens; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Female; Flow Cytometry; Gastrointestinal Tract; Interleukin-1 Receptor-Associated Kinases; Male; Metagenome; Mice; Mice, Inbred C57BL; Mice, Knockout; Real-Time Polymerase Chain Reaction; Receptors, Interleukin-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; T-Lymphocytes, Regulatory; Toll-Like Receptors | 2013 |
RNase-L deficiency exacerbates experimental colitis and colitis-associated cancer.
Topics: Animals; Azoxymethane; Blotting, Western; Carcinogens; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Endoribonucleases; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Immunity, Innate; Immunoenzyme Techniques; Interferon Type I; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peroxidase; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2013 |
Vitamin D receptor and retinoid X receptor α status and vitamin D insufficiency in models of murine colitis.
Topics: Acute Disease; Animals; Azoxymethane; Blotting, Western; Carcinogens; Cell Proliferation; Chronic Disease; Colitis; Colonic Neoplasms; Dextran Sulfate; Diet; Female; Immunoenzyme Techniques; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Receptors, Calcitriol; Retinoid X Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Snail Family Transcription Factors; Transcription Factors; Vitamin D Deficiency | 2013 |
Colitis-accelerated colorectal cancer and metabolic dysregulation in a mouse model.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Inflammation; Metabolic Diseases; Mice; Mice, Inbred BALB C; MicroRNAs; RNA, Messenger; Transcriptome; Up-Regulation; Wnt Proteins | 2013 |
IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice.
Topics: Animals; Azoxymethane; beta Catenin; Carcinogens; Cell Proliferation; Colitis; Colitis, Ulcerative; Colonic Neoplasms; Epithelial Cells; HCT116 Cells; Homeodomain Proteins; HT29 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Intestinal Mucosa; Kynurenine; Mice; Mice, Inbred C57BL; Mice, Knockout; Quinolinic Acid; Signal Transduction | 2013 |
Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.
Topics: Animals; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; DNA Damage; Genetic Predisposition to Disease; Histones; Humans; Mice; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Protein Isoforms; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2013 |
Intestine-Specific Mttp Deletion Increases the Severity of Experimental Colitis and Leads to Greater Tumor Burden in a Model of Colitis Associated Cancer.
Topics: Animals; Azoxymethane; Carrier Proteins; Cells, Cultured; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Feces; Interleukin-17; Interleukin-1beta; Intestines; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myofibroblasts; Severity of Illness Index; Tumor Burden; Tumor Necrosis Factor-alpha | 2013 |
Oroxylin A inhibits colitis-associated carcinogenesis through modulating the IL-6/STAT3 signaling pathway.
Topics: Animals; Azoxymethane; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Female; Flavonoids; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor | 2013 |
Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Azoxymethane; Carcinogenesis; Colitis; Colonic Neoplasms; Deoxyguanosine; Dextran Sulfate; Diet; DNA Damage; Epidermal Growth Factor; Gene Expression Regulation; Inflammation; Mice; Mice, Inbred C57BL; Selenium; Signal Transduction; Transforming Growth Factor beta; Weight Loss | 2013 |
Paradoxical role of the proto-oncogene Axl and Mer receptor tyrosine kinases in colon cancer.
Topics: Animals; Apoptosis; Axl Receptor Tyrosine Kinase; Azoxymethane; c-Mer Tyrosine Kinase; Colitis; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Female; Flow Cytometry; Gene Expression; Macrophages; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Mucous Membrane; Neutrophils; Phagocytosis; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2013 |
Sepiapterin ameliorates chemically induced murine colitis and azoxymethane-induced colon cancer.
Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Male; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Pterins | 2013 |
Baicalein, an active component of Scutellaria baicalensis Georgi, induces apoptosis in human colon cancer cells and prevents AOM/DSS-induced colon cancer in mice.
Topics: Animals; Antioxidants; Apoptosis; Azoxymethane; Blotting, Western; Carcinogens; Cell Movement; Cell Proliferation; Colitis; Colonic Neoplasms; Dextran Sulfate; Flavanones; Humans; Male; Mice; Mice, Inbred ICR; NF-kappa B; Poly(ADP-ribose) Polymerases; Scutellaria baicalensis; Tumor Cells, Cultured | 2013 |
Distribution of bone-marrow-derived endothelial and immune cells in a murine colitis-associated colorectal cancer model.
Topics: Animals; Azoxymethane; Bone Marrow Cells; Bone Marrow Transplantation; CD11c Antigen; CD4-Positive T-Lymphocytes; Cell Line; Colitis; Colorectal Neoplasms; Dendritic Cells; Dextran Sulfate; Endothelial Cells; Flow Cytometry; Green Fluorescent Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Platelet Endothelial Cell Adhesion Molecule-1 | 2013 |
Panax notoginseng attenuates experimental colitis in the azoxymethane/dextran sulfate sodium mouse model.
Topics: Animals; Azoxymethane; Colitis; Colon; Cyclooxygenase 2; Dextran Sulfate; Disease Models, Animal; Male; Mice; Nitric Oxide Synthase Type II; Panax notoginseng; Plant Extracts; Saponins | 2014 |
The importance of the retinoid X receptor alpha in modulating inflammatory signaling in acute murine colitis.
Topics: Animals; Azoxymethane; Carcinogens; Colitis; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Heterozygote; Immunoblotting; Inflammation; Mice; Receptors, Calcitriol; Retinoid X Receptor alpha | 2014 |
CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis.
Topics: Adoptive Transfer; Animals; Azoxymethane; Carcinogenesis; CD8-Positive T-Lymphocytes; Cells, Cultured; Chemokine CXCL1; Chemotaxis; Colitis; Colorectal Neoplasms; Cytotoxicity, Immunologic; Dextran Sulfate; Dinoprostone; Humans; Inflammation Mediators; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Mice, Knockout; Myeloid Cells; Receptors, Interleukin-8B; Tumor Microenvironment | 2013 |
Identification of a microRNA landscape targeting the PI3K/Akt signaling pathway in inflammation-induced colorectal carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2014 |
CD24 knockout prevents colorectal cancer in chemically induced colon carcinogenesis and in APC(Min)/CD24 double knockout transgenic mice.
Topics: Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; beta Catenin; Carcinogenesis; CD24 Antigen; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Dinoprostone; Disease Progression; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Promoter Regions, Genetic; Signal Transduction; Tumor Burden | 2014 |
MyD88 adaptor-like (Mal) regulates intestinal homeostasis and colitis-associated colorectal cancer in mice.
Topics: Animals; Azoxymethane; Bone Marrow Transplantation; Caco-2 Cells; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Homeostasis; Humans; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Interleukin-1; Severity of Illness Index; Time Factors; Transplantation Chimera | 2014 |
Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer.
Topics: Adaptor Proteins, Signal Transducing; Animals; Azoxymethane; Biopsy; Case-Control Studies; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Inflammation; Inflammatory Bowel Diseases; Mice; Mice, Knockout; NF-kappa B; Polymorphism, Single Nucleotide; RNA, Messenger | 2014 |
Identification of gene expression changes from colitis to CRC in the mouse CAC model.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Mice; Mice, Inbred BALB C; Protein Binding | 2014 |
Dynamic microbe and molecule networks in a mouse model of colitis-associated colorectal cancer.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Tract; Inflammation; Male; Mice; Mice, Inbred BALB C; RNA, Ribosomal, 16S | 2014 |
Nuclear adenomatous polyposis coli suppresses colitis-associated tumorigenesis in mice.
Topics: Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Azoxymethane; beta Catenin; Blotting, Western; Carcinogens; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Disease Models, Animal; Inflammation; Mice; Mutation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2014 |
Anti-inflammatory effects of betaine on AOM/DSS‑induced colon tumorigenesis in ICR male mice.
Topics: Animals; Anti-Inflammatory Agents; Azoxymethane; Betaine; Cell Line; Colitis; Colonic Neoplasms; Dextran Sulfate; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Macrophages; Male; Mice; Mice, Inbred ICR; Reactive Oxygen Species | 2014 |
Garcinol suppresses inflammation-associated colon carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; beta Catenin; Colitis; Colonic Neoplasms; Dextran Sulfate; Hepatitis; Inflammation Mediators; Lipid Metabolism; Male; Mice, Inbred ICR; Neoplasms, Experimental; Signal Transduction; Terpenes | 2014 |
[Changes of expression of miR-155 in colitis-associated colonic carcinogenesis].
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Cocarcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Gene Expression Profiling; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Precancerous Conditions; Up-Regulation | 2014 |
The role of corticotropin-releasing hormone receptor 1 in the development of colitis-associated cancer in mouse model.
Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Humans; Male; Mice, Knockout; NF-kappa B; Receptors, Corticotropin-Releasing Hormone; STAT3 Transcription Factor | 2014 |
Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.
Topics: Animals; Apoptosis; Azoxymethane; Cell Proliferation; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Gene Knockout Techniques; Humans; Inflammation; Lactoferrin; Male; Mice; NF-kappa B; Signal Transduction | 2014 |
[Inflammation promotes the development of colitis-associated colorectal cancer].
Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Immunohistochemistry; Inflammation; Interleukin-6; Mice; Mice, Inbred C57BL; Signal Transduction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha | 2014 |
Role of inflammation and inflammatory mediators in colorectal cancer.
Topics: Adenoma; Animals; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Genes, APC; Humans; Inflammation Mediators; Intestinal Mucosa; Mice, Inbred BALB C; Mice, Knockout; Rats; Receptors, Interleukin-8B | 2014 |
Activation of the mTORC1 and STAT3 pathways promotes the malignant transformation of colitis in mice.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred C57BL; Multiprotein Complexes; Signal Transduction; Sirolimus; STAT3 Transcription Factor; TOR Serine-Threonine Kinases | 2014 |
Nicotine suppresses acute colitis and colonic tumorigenesis associated with chronic colitis in mice.
Topics: Acute Disease; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Azoxymethane; CD4-Positive T-Lymphocytes; Chronic Disease; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Gastrointestinal Agents; Inflammation Mediators; Interleukin-6; Intestinal Mucosa; Male; Mice, Inbred BALB C; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; RNA, Messenger; Severity of Illness Index; STAT3 Transcription Factor; Time Factors; Tumor Necrosis Factor-alpha | 2014 |
Effect of genetic deletion or pharmacological antagonism of tumor necrosis factor alpha on colitis-associated carcinogenesis in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Etanercept; Female; Mice; Mice, Knockout; NF-kappa B; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2015 |
Role of milk fat globule-epidermal growth factor 8 in colonic inflammation and carcinogenesis.
Topics: Animals; Antigens, Surface; Azoxymethane; Body Weight; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Epithelial Cells; Humans; Integrin alphaVbeta3; Intestinal Mucosa; Mice, Knockout; Milk Proteins; Neoplasm Proteins; Recombinant Proteins; Tumor Cells, Cultured | 2015 |
15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway.
Topics: Animals; Arachidonate 15-Lipoxygenase; Azoxymethane; Blotting, Western; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Colitis; Colonic Neoplasms; Dextran Sulfate; Gene Expression; HCT116 Cells; Humans; Immunohistochemistry; Interleukin-6; Mice, Transgenic; Phosphorylation; PPAR delta; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; STAT3 Transcription Factor | 2015 |
NF-κB1, NF-κB2 and c-Rel differentially regulate susceptibility to colitis-associated adenoma development in C57BL/6 mice.
Topics: Adenoma; Animals; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Disease Susceptibility; Epithelial Cells; Female; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B p50 Subunit; NF-kappa B p52 Subunit; Proto-Oncogene Proteins c-rel; Signal Transduction | 2015 |
PAF receptor antagonist Ginkgolide B inhibits tumourigenesis and angiogenesis in colitis-associated cancer.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Dextran Sulfate; Female; Ginkgolides; Lactones; Mice; Neovascularization, Pathologic; Plant Extracts; Platelet Activating Factor | 2015 |
Registered report: Intestinal inflammation targets cancer-inducing activity of the microbiota.
Topics: Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Escherichia coli; Genomic Islands; Interleukin-10; Intestines; Metagenome; Mice, Knockout; Microbiota; Mutation; Polyketide Synthases; Sequence Deletion; Virulence | 2015 |
SPINK1 Status in Colorectal Cancer, Impact on Proliferation, and Role in Colitis-Associated Cancer.
Topics: Aged; Animals; Azoxymethane; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Colitis; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Glycoproteins; Humans; Inflammation; Japan; Male; Mice, Inbred C57BL; Middle Aged; Prostatic Secretory Proteins; Trypsin Inhibitor, Kazal Pancreatic | 2015 |
Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Adenocarcinoma; Animals; Azoxymethane; Binding Sites; Colitis; Colon; Colonic Neoplasms; Dishevelled Proteins; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Mice; Mice, Knockout; Phosphoproteins; Primary Cell Culture; Protein Binding; Protein Interaction Domains and Motifs; Protein Stability; RNA, Small Interfering; Sodium Dodecyl Sulfate; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2015 |
NPC1L1 knockout protects against colitis-associated tumorigenesis in mice.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azoxymethane; beta Catenin; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Homozygote; Intestinal Mucosa; Lipids; Membrane Transport Proteins; Mice; Mice, Knockout; Transforming Growth Factor beta; Tumor Suppressor Protein p53 | 2015 |
Mesenchymal stem cells-regulated Treg cells suppress colitis-associated colorectal cancer.
Topics: Animals; Azoxymethane; CD4 Lymphocyte Count; Cell Differentiation; Cell Line; Cell Movement; Cell- and Tissue-Based Therapy; Colitis; Colon; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Humans; Inflammation; Jurkat Cells; Lymphocyte Activation; Lymphocyte Count; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Signal Transduction; Smad2 Protein; T-Lymphocytes, Regulatory; Th17 Cells; Th2 Cells; Umbilical Cord | 2015 |
Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration.
Topics: Animals; Azoxymethane; beta Catenin; Cadherins; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Down-Regulation; Drugs, Chinese Herbal; Epithelial-Mesenchymal Transition; Fibronectins; Humans; Male; Mice, Inbred C57BL; Myeloid Cells; Phytotherapy; Proliferating Cell Nuclear Antigen; Transforming Growth Factor beta1; Vimentin | 2015 |
Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis.
Topics: Adenocarcinoma; Animals; Azoxymethane; Bacteroides fragilis; Blotting, Western; Carcinogenesis; Carcinogens; Cell Line, Tumor; Cell Proliferation; Chemokine CCL20; Colitis; Colonic Neoplasms; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Enterobacteriaceae; Exosomes; Immunohistochemistry; In Situ Hybridization, Fluorescence; Inflammation; Intestinal Mucosa; Lysophospholipids; Mice; Myeloid Differentiation Factor 88; Nanoparticles; Neoplasm Transplantation; Reverse Transcriptase Polymerase Chain Reaction; Sphingosine; Th17 Cells | 2015 |
Smad2/3 linker phosphorylation is a possible marker of cancer stem cells and correlates with carcinogenesis in a mouse model of colitis-associated colorectal cancer.
Topics: Animals; Azoxymethane; beta Catenin; Biomarkers, Tumor; Carcinogenesis; Colitis; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Ki-67 Antigen; Male; Mice; Neoplastic Stem Cells; Phosphorylation; Proto-Oncogene Proteins c-myc; Serine; Signal Transduction; Smad2 Protein; Smad3 Protein; SOX9 Transcription Factor | 2015 |
Development of an oral nanotherapeutics using redox nanoparticles for treatment of colitis-associated colon cancer.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Azoxymethane; Camptothecin; Cell Line, Tumor; Colitis; Colonic Neoplasms; Dextrans; Drug Delivery Systems; Drug Screening Assays, Antitumor; Endoscopy; Free Radical Scavengers; Inflammation; Irinotecan; Male; Mice; Mice, Inbred ICR; Nanomedicine; Nanoparticles; Neoplasms, Experimental; Nitrogen Oxides; Oxidation-Reduction; Reactive Oxygen Species; Sulfates | 2015 |
A critical role for cellular inhibitor of protein 2 (cIAP2) in colitis-associated colorectal cancer and intestinal homeostasis mediated by the inflammasome and survival pathways.
Topics: Animals; Azoxymethane; Baculoviral IAP Repeat-Containing 3 Protein; Cell Death; Cell Survival; Colitis; Colon; Colorectal Neoplasms; Gene Expression Regulation; Humans; Inflammasomes; Inhibitor of Apoptosis Proteins; Interleukin-18; Male; Mice; Mice, Knockout; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction; Sodium Dodecyl Sulfate; Ubiquitin-Protein Ligases | 2016 |
Activation of AMPK by chitosan oligosaccharide in intestinal epithelial cells: Mechanism of action and potential applications in intestinal disorders.
Topics: AMP-Activated Protein Kinases; Animals; Azoxymethane; beta Catenin; Calcium; Caspase 3; Cell Line, Tumor; Chitosan; Cholera Toxin; Colitis; Colorectal Neoplasms; Dextran Sulfate; Epithelial Cells; Gastrointestinal Agents; Gene Expression Regulation; Humans; Inositol 1,4,5-Trisphosphate Receptors; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Receptors, Calcium-Sensing; Receptors, G-Protein-Coupled; Signal Transduction; Type C Phospholipases | 2015 |
Calpain-2 Inhibitor Therapy Reduces Murine Colitis and Colitis-associated Cancer.
Topics: Animals; Azoxymethane; Cell Proliferation; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; HT29 Cells; Humans; I-kappa B Proteins; Inflammation; Injections, Intraperitoneal; Macrophage Activation; Mice; NF-kappa B; Oligopeptides; Translocation, Genetic | 2015 |
Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer.
Topics: Animals; Azoxymethane; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; DNA-Binding Proteins; Enterocytes; Gastrointestinal Tract; Inflammasomes; Mice; Mutation; Stem Cells | 2015 |
The MUTYH base excision repair gene protects against inflammation-associated colorectal carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Bone Marrow Cells; CD8-Positive T-Lymphocytes; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; DNA Glycosylases; Forkhead Transcription Factors; Guanine; Inflammation Mediators; Mice, Knockout; T-Lymphocytes, Regulatory; Time Factors | 2015 |
Mast Cells Infiltrating Inflamed or Transformed Gut Alternatively Sustain Mucosal Healing or Tumor Growth.
Topics: Animals; Animals, Congenic; Azoxymethane; Carcinoma; Cell Count; Cell Transformation, Neoplastic; Cells, Cultured; Colitis; Colonic Neoplasms; Dextran Sulfate; Epithelial Cells; Humans; Inflammatory Bowel Diseases; Interleukin-1 Receptor-Like 1 Protein; Interleukin-33; Intestinal Mucosa; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Proto-Oncogene Proteins c-kit; Receptors, Interleukin; Regeneration; Serine Endopeptidases; Species Specificity; Specific Pathogen-Free Organisms | 2015 |
The Role of Curcumin in Modulating Colonic Microbiota During Colitis and Colon Cancer Prevention.
Topics: Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Curcumin; Dietary Supplements; Disease Models, Animal; Immunity, Mucosal; Intestinal Mucosa; Mice; Mice, 129 Strain; Mice, Knockout; Microbiota | 2015 |
Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice.
Topics: Animals; Azoxymethane; Cell Membrane; Colitis; Colon; Colonic Neoplasms; Cytosol; Dextran Sulfate; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Dominant; Genetic Predisposition to Disease; Glycosylation; HeLa Cells; Humans; Inflammation Mediators; Intestinal Mucosa; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Oligonucleotide Array Sequence Analysis; Phenotype; Protein Processing, Post-Translational; Receptors, Interleukin-1; RNA, Messenger; Signal Transduction; Tissue Culture Techniques; Transfection | 2015 |
Dietary cocoa inhibits colitis associated cancer: a crucial involvement of the IL-6/STAT3 pathway.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Azoxymethane; bcl-2-Associated X Protein; bcl-X Protein; Cacao; Caspase 3; Colitis; Colorectal Neoplasms; Dextran Sulfate; Diet; Epithelial Cells; Female; Gene Expression Regulation; Inflammatory Bowel Diseases; Interleukin-6; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Neoplasms; Peroxidase; Polyphenols; Signal Transduction; STAT3 Transcription Factor | 2015 |
A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations.
Topics: Adenomatous Polyps; Animals; Azoxymethane; beta Catenin; Cell Transformation, Neoplastic; Colitis; Colon; Colonic Neoplasms; Colonic Polyps; Cytokines; Gene Expression Regulation, Neoplastic; Genes, APC; Genetic Predisposition to Disease; Heterozygote; Homozygote; Humans; Matrix Metalloproteinase 7; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neoplasm Staging; Neovascularization, Pathologic; Paneth Cells; Phenotype; Tenascin; Tumor Microenvironment; Wnt Signaling Pathway | 2015 |
Chemopreventive effect of oleuropein in colitis-associated colorectal cancer in c57bl/6 mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Cell Proliferation; Colitis; Colon; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Female; Iridoid Glucosides; Iridoids; Mice, Inbred C57BL; Neoplasms, Experimental; Th17 Cells | 2016 |
Dead Nano-Sized Lactobacillus plantarum Inhibits Azoxymethane/Dextran Sulfate Sodium-Induced Colon Cancer in Balb/c Mice.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogenesis; Cell Cycle Checkpoints; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Immunoglobulin A; Inflammation; Lactobacillus plantarum; Mice, Inbred BALB C; Particle Size | 2015 |
Dietary Ziziphus jujuba Fruit Influence on Aberrant Crypt Formation and Blood Cells in Colitis-Associated Colorectal Cancer in Mice.
Topics: Aberrant Crypt Foci; Adenocarcinoma; Animals; Azoxymethane; Carcinogenesis; Chemoprevention; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Diet; Dietary Supplements; Disease Progression; Hyperplasia; Leukocyte Count; Leukocytes; Male; Mice; Mice, Inbred C57BL; Plant Preparations; Ziziphus | 2015 |
Suppression of colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway by balsalazide and VSL#3.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Azoxymethane; bcl-2-Associated X Protein; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Agents; Inflammation Mediators; Interleukin-6; Macrophages; Male; Mesalamine; Mice, Inbred C57BL; Phenylhydrazines; Phosphorylation; Probiotics; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; STAT3 Transcription Factor; Time Factors | 2016 |
Sonic hedgehog inhibitors prevent colitis-associated cancer via orchestrated mechanisms of IL-6/gp130 inhibition, 15-PGDH induction, Bcl-2 abrogation, and tumorsphere inhibition.
Topics: Animals; Apoptosis; Azoxymethane; Blotting, Western; Cell Movement; Cell Proliferation; Cerulenin; Colitis; Colonic Neoplasms; Cytokine Receptor gp130; Fatty Acid Synthesis Inhibitors; Flow Cytometry; Fluorescent Antibody Technique; Hedgehog Proteins; Humans; Hydroxyprostaglandin Dehydrogenases; Immunoenzyme Techniques; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-bcl-2; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spheroids, Cellular; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zinc Finger Protein GLI1 | 2016 |
PDCD4 Deficiency Aggravated Colitis and Colitis-associated Colorectal Cancer Via Promoting IL-6/STAT3 Pathway in Mice.
Topics: Animals; Apoptosis Regulatory Proteins; Azoxymethane; Blotting, Western; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cytokines; Female; Immunoenzyme Techniques; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Real-Time Polymerase Chain Reaction; RNA-Binding Proteins; Signal Transduction; STAT3 Transcription Factor | 2016 |
[Changes of macrophages in colitis-associated colonic carcinogenesis].
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Granulocyte Colony-Stimulating Factor; Macrophages; Mice; Mice, Inbred C57BL; Phenotype; Real-Time Polymerase Chain Reaction | 2016 |
Vancomycin-sensitive bacteria trigger development of colitis-associated colon cancer by attracting neutrophils.
Topics: Animals; Azoxymethane; Bacteria; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; DNA Damage; Gene Expression Regulation; Humans; Mice; Neutrophils; Vancomycin | 2016 |
MicroRNA-17~92 inhibits colorectal cancer progression by targeting angiogenesis.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Progression; Gene Expression Regulation, Neoplastic; HCT116 Cells; Heterografts; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice, Nude; Mice, Transgenic; MicroRNAs; Neoplasm Transplantation; Neovascularization, Pathologic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Long Noncoding; Time Factors; Vascular Endothelial Growth Factor A | 2016 |
Acute blockade of IL-25 in a colitis associated colon cancer model leads to increased tumor burden.
Topics: Animals; Antibodies, Neutralizing; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Eosinophils; Gene Deletion; Gene Expression Regulation; Interleukin-17; Mice, Inbred BALB C; Tumor Burden | 2016 |
The epigenetic effects of aspirin: the modification of histone H3 lysine 27 acetylation in the prevention of colon carcinogenesis in azoxymethane- and dextran sulfate sodium-treated CF-1 mice.
Topics: Animals; Anticarcinogenic Agents; Aspirin; Azoxymethane; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Epigenesis, Genetic; Histone Deacetylases; Histones; Lysine; Male; Mice, Inbred Strains; Neoplasms, Experimental; Nitric Oxide Synthase Type II | 2016 |
AOM/DSS Model of Colitis-Associated Cancer.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Mice | 2016 |
Epidermal growth factor is a critical regulator of the cytokine IL-33 in intestinal epithelial cells.
Topics: Animals; Azoxymethane; Cells, Cultured; Colitis; Dextran Sulfate; EGF Family of Proteins; Epithelial Cells; Interleukin-1 Receptor-Like 1 Protein; Interleukin-33; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred C57BL; Rats | 2016 |
The Aryl Hydrocarbon Receptor is a Repressor of Inflammation-associated Colorectal Tumorigenesis in Mouse.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; DNA Damage; Gene Expression; Indoles; Mice; Mice, Inbred C57BL; Receptors, Aryl Hydrocarbon; RNA | 2016 |
American Ginseng Attenuates Colitis-Associated Colon Carcinogenesis in Mice: Impact on Gut Microbiota and Metabolomics.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Gastrointestinal Microbiome; Male; Metabolomics; Mice; Panax | 2016 |
Dietary Nanosized Lactobacillus plantarum Enhances the Anticancer Effect of Kimchi on Azoxymethane and Dextran Sulfate Sodium-Induced Colon Cancer in C57BL/6J Mice.
Topics: Animals; Azoxymethane; Carcinogens; Colitis; Colon; Dextran Sulfate; Diet; Fermentation; Functional Food; Lactobacillus plantarum; Male; Mice; Mice, Inbred BALB C; Probiotics | 2016 |
Flavonoids Extracted from Licorice Prevents Colitis-Associated Carcinogenesis in AOM/DSS Mouse Model.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogenesis; Cell Proliferation; Colitis; Dextran Sulfate; Disease Models, Animal; Female; Flavonoids; Glycyrrhiza; Inflammatory Bowel Diseases; Interleukin-6; Janus Kinase 2; Mice; Mice, Inbred C57BL; NF-kappa B; Signal Transduction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2016 |
Prevention of azoxymethane/dextran sodium sulfate-induced mouse colon carcinogenesis by processed Aloe vera gel.
Topics: Adenocarcinoma; Aloe; Animals; Azoxymethane; Carcinogenesis; CDX2 Transcription Factor; Cell Cycle; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gels; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; NF-kappa B; Plant Extracts; Tumor Suppressor Proteins | 2016 |
Anti-inflammatory natural product goniothalamin reduces colitis-associated and sporadic colorectal tumorigenesis.
Topics: Animals; Anti-Inflammatory Agents; Azoxymethane; Biological Products; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Inflammation; Inflammation Mediators; Macrophages; Mice; Mice, Inbred C57BL; Pyrones | 2017 |
Repression of MicroRNA Function Mediates Inflammation-associated Colon Tumorigenesis.
Topics: Animals; Azoxymethane; Caco-2 Cells; Carcinogenesis; Carcinoma; Cell Line, Tumor; Colitis; Colon; Colonic Neoplasms; Cytidine Deaminase; Cytokines; DEAD-box RNA Helicases; Dextran Sulfate; Fibroblasts; Flow Cytometry; HCT116 Cells; HT29 Cells; Humans; Immunoblotting; Immunohistochemistry; Inflammation; Interleukin-1alpha; Interleukin-1beta; Mice; MicroRNAs; Ribonuclease III; Tumor Necrosis Factor-alpha | 2017 |
Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor-κB, and Up-regulating Expression of MicroRNA-21.
Topics: Adenomatous Polyposis Coli Protein; Aged; Animals; Azoxymethane; Carcinogenesis; Cell Movement; Cell Proliferation; Colitis; Colonic Neoplasms; Dextran Sulfate; DNA, Bacterial; Down-Regulation; Female; Fusobacterium Infections; Fusobacterium nucleatum; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; MicroRNAs; Myeloid Differentiation Factor 88; NF-kappa B; p120 GTPase Activating Protein; Prognosis; RNA, Small Interfering; Signal Transduction; Toll-Like Receptor 4; Up-Regulation | 2017 |
T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice.
Topics: Animals; Azoxymethane; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Colitis; Colonic Neoplasms; Cytotoxicity, Immunologic; Dextran Sulfate; Disease Models, Animal; Fas Ligand Protein; Granzymes; Inflammation Mediators; Interferon-gamma; Lymphocytes, Tumor-Infiltrating; Mice, Knockout; Perforin; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Signal Transduction; STAT1 Transcription Factor; Time Factors; Tumor Microenvironment | 2017 |
Cilostazol and enzymatically modified isoquercitrin attenuate experimental colitis and colon cancer in mice by inhibiting cell proliferation and inflammation.
Topics: Animals; Azoxymethane; Carcinogens; Cell Proliferation; Cilostazol; Colitis; Colonic Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; Immunohistochemistry; Inflammation; Mice; Mice, Inbred BALB C; Organ Size; Quercetin; Tetrazoles; Vasodilator Agents | 2017 |
RNA virus receptor Rig-I monitors gut microbiota and inhibits colitis-associated colorectal cancer.
Topics: Animals; Azoxymethane; Bacteria; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; DNA, Bacterial; Down-Regulation; Gastrointestinal Microbiome; Humans; Immunoglobulin A; Interleukin-6; Membrane Proteins; Mice; Nerve Tissue Proteins; Pancreatitis-Associated Proteins; Phosphorylation; Phylogeny; Receptors, Cell Surface; Receptors, Retinoic Acid; Sequence Analysis, DNA; STAT3 Transcription Factor | 2017 |
MicroRNA 301A Promotes Intestinal Inflammation and Colitis-Associated Cancer Development by Inhibiting BTG1.
Topics: Aged; Animals; Azoxymethane; Cadherins; Case-Control Studies; Cell Proliferation; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Down-Regulation; Epithelial Cells; Female; Gene Expression; HCT116 Cells; Humans; Inflammatory Breast Neoplasms; Interleukin-1beta; Intestinal Mucosa; JNK Mitogen-Activated Protein Kinases; Male; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Middle Aged; Neoplasm Proteins; Neoplasm Transplantation; RNA, Messenger; Signal Transduction; Transcription Factor RelA; Transfection; Tumor Burden; Up-Regulation | 2017 |
WD-repeat protein WDR13 is a novel transcriptional regulator of c-Jun and modulates intestinal homeostasis in mice.
Topics: Animals; Azoxymethane; Cell Cycle Proteins; Cell Line; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation, Neoplastic; HEK293 Cells; Homeostasis; HT29 Cells; Humans; MCF-7 Cells; Mice; Nuclear Proteins; Proto-Oncogene Proteins c-jun; Signal Transduction | 2017 |
Exploration of Inflammatory Bowel Disease in Mice: Chemically Induced Murine Models of Inflammatory Bowel Disease (IBD).
Topics: Acute Disease; Animals; Azoxymethane; Cell Transformation, Neoplastic; Chronic Disease; Colitis; Dextran Sulfate; Disease Models, Animal; Humans; Inflammatory Bowel Diseases; Mice; Trinitrobenzenesulfonic Acid | 2017 |
The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice.
Topics: Animals; Azoxymethane; beta Catenin; Colitis; Colonic Neoplasms; Genes, APC; Intestinal Mucosa; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Signal Transduction; Transcription Factor AP-1 | 2008 |
A novel prodrug of 4'-geranyloxy-ferulic acid suppresses colitis-related colon carcinogenesis in mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenocarcinoma; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Chemoprevention; Colitis; Colonic Neoplasms; Coumaric Acids; Deoxyguanosine; Dextran Sulfate; Dipeptides; Disease Models, Animal; Heme Oxygenase (Decyclizing); Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; Oxidative Stress; Prodrugs | 2008 |
Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer.
Topics: Animals; Azoxymethane; Biomarkers; Brain Chemistry; Carcinogens; Carrier Proteins; Colitis; Colonic Neoplasms; Dextran Sulfate; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Deficiency; Food, Formulated; Heterozygote; Homocysteine; Intestinal Mucosa; Membrane Transport Proteins; Mice; Mice, Knockout; Models, Animal; Nutritional Status; Precancerous Conditions; Receptors, Cell Surface; Reduced Folate Carrier Protein | 2009 |
Citrus compounds inhibit inflammation- and obesity-related colon carcinogenesis in mice.
Topics: Animals; Azoxymethane; Citrus; Colitis; Colonic Neoplasms; Coumarins; Cyclooxygenase 2; Interleukin-1beta; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Obesity; Precancerous Conditions; Tumor Necrosis Factor-alpha | 2008 |
The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis.
Topics: Animals; Azoxymethane; Chemokines; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Female; Genes, APC; Immunity, Innate; Intestines; Male; Mice; Mice, Inbred C57BL; Nod1 Signaling Adaptor Protein; Receptors, Immunologic; RNA, Messenger; Specific Pathogen-Free Organisms | 2008 |
Increased susceptibility of Nrf2 knockout mice to colitis-associated colorectal cancer.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Cytoprotection; Dextran Sulfate; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2 | 2008 |
The absence of LPA2 attenuates tumor formation in an experimental model of colitis-associated cancer.
Topics: Animals; Azoxymethane; beta Catenin; Cell Proliferation; Chemokine CCL2; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cytokines; Disease Progression; Genes, APC; Kruppel-Like Transcription Factors; Lipopolysaccharides; Macrophage Migration-Inhibitory Factors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Lysophosphatidic Acid | 2009 |
3,3'-diindolylmethane attenuates colonic inflammation and tumorigenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Indoles; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide; Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Weight Loss | 2009 |
Mucin-depleted foci show strong activation of inflammatory markers in 1,2-dimethylhydrazine-induced carcinogenesis and are promoted by the inflammatory agent sodium dextran sulfate.
Topics: 1,2-Dimethylhydrazine; Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Inflammation; Male; Mucin-2; Nitric Oxide Synthase Type II; Precancerous Conditions; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2009 |
Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Benzamides; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Drug Delivery Systems; Drug Screening Assays, Antitumor; I-kappa B Kinase; Macrophages; Male; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; NF-kappa B; Peptides | 2009 |
Epithelial vanin-1 controls inflammation-driven carcinogenesis in the colitis-associated colon cancer model.
Topics: Amidohydrolases; Animals; Azoxymethane; Blotting, Western; Carcinogens; Cell Adhesion Molecules; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Epithelial Cells; Female; Fluorescent Antibody Technique; GPI-Linked Proteins; Inflammation; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Inhibition of colon carcinogenesis by 2-methoxy-5-amino-N-hydroxybenzamide, a novel derivative of mesalamine.
Topics: Aminosalicylic Acids; Animals; Anticarcinogenic Agents; Azoxymethane; Benzamides; Carcinogens; Cell Death; Cell Division; Colitis; Colonic Neoplasms; Cyclin D1; Dextran Sulfate; eIF-2 Kinase; Endoplasmic Reticulum; Flow Cytometry; G1 Phase; Gene Silencing; HCT116 Cells; Humans; Mesalamine; Mice; Resting Phase, Cell Cycle; Xenograft Model Antitumor Assays | 2010 |
Apoptosis signal-regulating kinase 1 regulates colitis and colitis-associated tumorigenesis by the innate immune responses.
Topics: Animals; Apoptosis; Azoxymethane; Bone Marrow Transplantation; Cell Proliferation; Cells, Cultured; Citrobacter rodentium; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Susceptibility; Female; Gene Expression Regulation; Humans; Immunity, Innate; Macrophages; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred C57BL; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Phagocytosis; RNA Interference; Severity of Illness Index; Time Factors | 2010 |
Increased visceral fat mass and insulin signaling in colitis-related colon carcinogenesis model mice.
Topics: Animals; Azoxymethane; Carcinogens; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Insulin; Insulin-Like Growth Factor I; Intra-Abdominal Fat; Leptin; Male; Mice; Mice, Inbred ICR; Signal Transduction | 2010 |
Phosphatidylinositol 3-kinase gamma inhibition ameliorates inflammation and tumor growth in a model of colitis-associated cancer.
Topics: Animals; Azoxymethane; CD4-Positive T-Lymphocytes; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Immunity, Innate; Inflammatory Bowel Diseases; Mice; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors | 2010 |
Tumor formation in a mouse model of colitis-associated colon cancer does not require COX-1 or COX-2 expression.
Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Dextran Sulfate; Genes, APC; Membrane Proteins; Mice; Mice, Knockout; NF-kappa B; Toll-Like Receptor 4 | 2010 |
Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Azoxymethane; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Cycle Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Disease Models, Animal; Disease Progression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Inhibitor of Apoptosis Proteins; Male; Mice; Mice, Inbred ICR; Microdissection; Microtubule-Associated Proteins; Nitric Oxide Synthase Type II; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myb; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Survivin; Telomerase; Transcription Factor 4 | 2010 |
CCL2 (pM levels) as a therapeutic agent in Inflammatory Bowel Disease models in mice.
Topics: Animals; Azoxymethane; Blotting, Western; Carcinogens; Cell Adhesion; Cell Movement; Cell Proliferation; Chemokine CCL2; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunoenzyme Techniques; Inflammatory Bowel Diseases; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Trinitrobenzenesulfonic Acid | 2010 |
Colitis-associated cancer is dependent on the interplay between the hemostatic and inflammatory systems and supported by integrin alpha(M)beta(2) engagement of fibrinogen.
Topics: Adenoma; Animals; Azoxymethane; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Progression; Fibronectins; Hemostasis; Macrophage-1 Antigen; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic | 2010 |
Bifidobacterium lactis inhibits NF-kappaB in intestinal epithelial cells and prevents acute colitis and colitis-associated colon cancer in mice.
Topics: Acute Disease; Animals; Azoxymethane; Bifidobacteriales Infections; Bifidobacterium; Blotting, Western; Carcinogens; Chronic Disease; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Immunoenzyme Techniques; Inflammation; Intestinal Mucosa; Lipopolysaccharides; Luciferases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Epimorphin deletion protects mice from inflammation-induced colon carcinogenesis and alters stem cell niche myofibroblast secretion.
Topics: Animals; Azoxymethane; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Epithelial Cells; Inflammation; Interleukin-6; Intestinal Mucosa; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; Sequence Deletion | 2010 |
2,3',4,4',5'-Pentamethoxy-trans-stilbene, a resveratrol derivative, inhibits colitis-associated colorectal carcinogenesis in mice.
Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Cell Line, Tumor; Cell Proliferation; Colitis; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred BALB C; Stilbenes | 2010 |
The role of prostaglandin E2 (PGE 2) in toll-like receptor 4 (TLR4)-mediated colitis-associated neoplasia.
Topics: Amphiregulin; Animals; Azoxymethane; Cell Proliferation; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; EGF Family of Proteins; ErbB Receptors; Female; Glycoproteins; Intercellular Signaling Peptides and Proteins; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prostaglandins; Signal Transduction; Toll-Like Receptor 4 | 2010 |
Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase.
Topics: Adamantane; Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Extracellular Signal-Regulated MAP Kinases; Lysophospholipids; Mice; Mice, Inbred C57BL; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-akt; Pyridines; Sphingosine | 2010 |
Mechanistic insight into the ability of American ginseng to suppress colon cancer associated with colitis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Female; HSP90 Heat-Shock Proteins; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 7; Panax; PAX2 Transcription Factor; Phytotherapy; Plant Extracts | 2010 |
Western-style diets induce macrophage infiltration and contribute to colitis-associated carcinogenesis.
Topics: Animals; Azoxymethane; beta Catenin; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Diet; Dinoprostone; Disease Susceptibility; Hydroxyprostaglandin Dehydrogenases; Macrophages; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Signal Transduction; Statistics, Nonparametric; Tumor Necrosis Factor-alpha | 2010 |
MTGR1 is required for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model.
Topics: Animals; Azoxymethane; Carcinoma; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Progression; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Repressor Proteins | 2011 |
A two-locus system controls susceptibility to colitis-associated colon cancer in mice.
Topics: Animals; Azoxymethane; Carcinogens; Chromosome Mapping; Chromosomes, Mammalian; Colitis; Colorectal Neoplasms; Crosses, Genetic; Disease Models, Animal; Female; Genetic Linkage; Genetic Loci; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Quantitative Trait Loci | 2010 |
The Wnt antagonist Dkk1 regulates intestinal epithelial homeostasis and wound repair.
Topics: Acute Disease; Animals; Antibodies, Monoclonal; Azoxymethane; beta Catenin; Cell Proliferation; Cells, Cultured; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Homeostasis; Injections, Intraperitoneal; Intercellular Signaling Peptides and Proteins; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Transgenic; Signal Transduction; Time Factors; Wnt Proteins; Wound Healing | 2011 |
Effects of diet-induced obesity on colitis-associated colon tumor formation in A/J mice.
Topics: Animals; Azoxymethane; Blotting, Western; Carcinogens; Colitis; Colon; Colonic Neoplasms; Diet, High-Fat; Disease Models, Animal; Male; Mice; Obesity; Signal Transduction | 2012 |
Dietary astaxanthin inhibits colitis and colitis-associated colon carcinogenesis in mice via modulation of the inflammatory cytokines.
Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Dietary Supplements; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred ICR; NF-kappa B; Tumor Necrosis Factor-alpha; Xanthophylls | 2011 |
The neurotensin receptor-1 promotes tumor development in a sporadic but not an inflammation-associated mouse model of colon cancer.
Topics: Animals; Azoxymethane; Chemokine CXCL2; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gene Expression; Humans; Immunohistochemistry; Interleukin-6; Kaplan-Meier Estimate; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Pyrazoles; Quinolines; Receptors, Neurotensin; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tumor Necrosis Factor-alpha | 2012 |
Dynamics of claudins expression in colitis and colitis-associated cancer in rat.
Topics: Animals; Azoxymethane; Blotting, Western; Busulfan; Claudins; Colitis; Colonic Neoplasms; Dextran Sulfate; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Expression Profiling; Gene Expression Regulation; Immunoblotting; Microscopy, Fluorescence; Rats; Tight Junctions | 2011 |
Notch1 regulates the effects of matrix metalloproteinase-9 on colitis-associated cancer in mice.
Topics: Amyloid Precursor Protein Secretases; Animals; Apoptosis; Azoxymethane; Caspase 3; Colitis; Colon; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cytokines; Dextran Sulfate; Dipeptides; Disease Models, Animal; DNA Damage; Enzyme Inhibitors; Fibroblasts; Gamma Rays; HCT116 Cells; Humans; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Notch1; RNA, Messenger; Signal Transduction; Time Factors; Transfection; Tumor Suppressor Protein p53 | 2011 |
Prevention of colitis-associated colorectal cancer with 8-hydroxydeoxyguanosine.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticarcinogenic Agents; Azoxymethane; Colitis; Colorectal Neoplasms; Deoxyguanosine; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation; Interleukin-10; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms; STAT3 Transcription Factor; Sulfates | 2011 |
Characterization of chromosomal instability in murine colitis-associated colorectal cancer.
Topics: Animals; Azoxymethane; beta Catenin; Cell Proliferation; Chromosomal Instability; Colitis; Colorectal Neoplasms; Dextran Sulfate; Endoscopy, Digestive System; Gene Expression Regulation, Neoplastic; Humans; Interferon-gamma; Interleukin-10; Ki-67 Antigen; Mice; Neoplasm Staging; Tumor Suppressor Protein p53 | 2011 |
Involvement of interleukin-21 in the regulation of colitis-associated colon cancer.
Topics: Animals; Azoxymethane; Carcinogens; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Forkhead Transcription Factors; Humans; Interleukin-17; Interleukin-6; Interleukins; Mice; Mice, Inbred C57BL; Mice, Knockout; STAT3 Transcription Factor | 2011 |
Chronic psychosocial stress increases the risk for inflammation-related colon carcinogenesis in male mice.
Topics: Animals; Azoxymethane; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Housing, Animal; Inflammation; Interferon-gamma; Male; Mice; Mice, Inbred C57BL; Social Dominance; Stress, Psychological | 2012 |
Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply.
Topics: Animals; Apoptosis; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Glutathione Peroxidase; Glutathione Transferase; Ileum; Inflammation; Isothiocyanates; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Selenium; Sulfoxides; Thiocyanates; Thioredoxin-Disulfide Reductase | 2012 |
Glucagon-like peptide-2 increases dysplasia in rodent models of colon cancer.
Topics: Animals; Azoxymethane; beta Catenin; Blotting, Western; Carcinogens; Colitis; Colonic Neoplasms; Dextran Sulfate; Diet, High-Fat; Doublecortin Protein; Glucagon-Like Peptide 2; Imidazoles; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Inbred F344; Real-Time Polymerase Chain Reaction; RNA, Messenger | 2012 |
Suppressive effects of Moringa oleifera Lam pod against mouse colon carcinogenesis induced by azoxymethane and dextran sodium sulfate.
Topics: Animals; Azoxymethane; Carcinogens; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Immunoenzyme Techniques; Male; Mice; Mice, Inbred ICR; Moringa oleifera; Nitric Oxide Synthase Type II; Phytotherapy; Plant Extracts | 2011 |
IEX-1 deficiency protects against colonic cancer.
Topics: Animals; Apoptosis; Azoxymethane; Cell Proliferation; Colitis; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Epithelial Cells; Female; Gene Expression; GTP-Binding Protein alpha Subunit, Gi2; Immediate-Early Proteins; Intestinal Mucosa; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Reverse Transcriptase Polymerase Chain Reaction; Th17 Cells | 2012 |
Arsenic and chromium in drinking water promote tumorigenesis in a mouse colitis-associated colorectal cancer model and the potential mechanism is ROS-mediated Wnt/β-catenin signaling pathway.
Topics: Animals; Antioxidants; Arsenic; Azoxymethane; Carcinogens, Environmental; Cell Line; Chromium; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Drinking Water; Electrophoresis, Gel, Two-Dimensional; Humans; Mass Spectrometry; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Water Pollutants, Chemical; Wnt Signaling Pathway | 2012 |
RETRACTED: Obesity-induced increase in tumor necrosis factor-α leads to development of colon cancer in mice.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Azoxymethane; Blotting, Western; Cell Proliferation; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Enzyme Activation; HT29 Cells; Humans; Hyperinsulinism; Hypoglycemic Agents; I-kappa B Kinase; Immunohistochemistry; Inflammation Mediators; Infliximab; Insulin; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; Mice, SCID; Obesity; Phosphatidylinositol 3-Kinase; Pioglitazone; Proto-Oncogene Proteins c-akt; Signal Transduction; Thiazolidinediones; Time Factors; TOR Serine-Threonine Kinases; Tumor Burden; Tumor Necrosis Factor-alpha; Up-Regulation; Xenograft Model Antitumor Assays | 2012 |
DNA repair is indispensable for survival after acute inflammation.
Topics: AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase; Animals; Azoxymethane; Carcinogens; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Dioxygenases; DNA Glycosylases; DNA Repair; DNA Repair Enzymes; Epistasis, Genetic; Female; Genetic Predisposition to Disease; Kaplan-Meier Estimate; Lethal Dose 50; Lipopolysaccharides; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Pancreas; Pancreatitis | 2012 |
Deleterious effects of high concentrations of (-)-epigallocatechin-3-gallate and atorvastatin in mice with colon inflammation.
Topics: Animals; Atorvastatin; Azoxymethane; Catechin; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gastrointestinal Hemorrhage; Heptanoic Acids; Leukotriene B4; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Pyrroles; Rectum; Weight Loss | 2012 |
Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammation.
Topics: Animals; Azoxymethane; Carcinogens; Chromosome Mapping; Chromosomes, Mammalian; Colitis; Colorectal Neoplasms; Disease Resistance; Genetic Loci; Genetic Predisposition to Disease; Helicobacter hepaticus; Helicobacter Infections; Host-Pathogen Interactions; Humans; Immunity, Innate; Inflammation; Mice; Mice, 129 Strain; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Polymorphism, Single Nucleotide; Telomere | 2012 |
Reduced susceptibility to colitis-associated colon carcinogenesis in mice lacking plasma membrane-associated sialidase.
Topics: Animals; Azoxymethane; Cell Membrane; Colitis; Colonic Neoplasms; Dextrans; Gangliosides; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Genetic Vectors; Genotype; Glycoconjugates; Glycolipids; Mice; Mice, Transgenic; Neuraminidase; Sialic Acids; Sulfates | 2012 |
Deletion of p38-alpha mitogen-activated protein kinase within the intestinal epithelium promotes colon tumorigenesis.
Topics: Adenoma; Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Enterocytes; Feces; Intestinal Mucosa; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 14; Weight Loss | 2012 |
Intestinal inflammation targets cancer-inducing activity of the microbiota.
Topics: Animals; Azoxymethane; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; DNA Damage; Escherichia coli; Interleukin-10; Intestines; Metagenome; Mice; Mice, Mutant Strains; Polyketide Synthases; Sequence Deletion | 2012 |
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Animals, Inbred Strains; Azoxymethane; Cell Transformation, Neoplastic; Chemokines, CXC; Colitis; Colonic Neoplasms; Dermatitis, Contact; Dextran Sulfate; Gene Expression; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Papilloma; Peroxidase; Precancerous Conditions; Receptors, Interleukin-8B; Skin Neoplasms; Statistics, Nonparametric; Tetradecanoylphorbol Acetate; Tumor Burden | 2012 |
Modeling colitis-associated cancer with azoxymethane (AOM) and dextran sulfate sodium (DSS).
Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Male; Mice | 2012 |
Mice that express human interleukin-8 have increased mobilization of immature myeloid cells, which exacerbates inflammation and accelerates colon carcinogenesis.
Topics: Animals; Azoxymethane; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dendritic Cells; Dextran Sulfate; Gastritis; Helicobacter felis; Helicobacter Infections; Humans; Interleukin-8; Lipopolysaccharides; Macrophages; Mice; Mice, Transgenic; Myeloid Cells; Primary Cell Culture; RNA, Messenger; Tumor Burden; Up-Regulation | 2013 |
Tpl2 regulates intestinal myofibroblast HGF release to suppress colitis-associated tumorigenesis.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Dextran Sulfate; Hepatocyte Growth Factor; Intestinal Mucosa; Intestinal Neoplasms; Intestines; MAP Kinase Kinase Kinases; Mice; Mice, Knockout; Mucous Membrane; Myofibroblasts; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Signal Transduction | 2012 |
Organomagnesium suppresses inflammation-associated colon carcinogenesis in male Crj: CD-1 mice.
Topics: Adenocarcinoma; Adenoma; Animals; Apoptosis; Azoxymethane; Blotting, Western; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Humans; Immunoenzyme Techniques; Inflammation; Interferon-gamma; Interleukin-1beta; Interleukin-6; Magnesium Compounds; Male; Mice; Mice, Inbred ICR; Mitotic Index; Organometallic Compounds; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2013 |
A polyacetylene-rich extract from Gymnaster koraiensis strongly inhibits colitis-associated colon cancer in mice.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Asteraceae; Azoxymethane; Cell Proliferation; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Inflammation; Liver; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Polyynes | 2013 |
Chemoprevention for colorectal tumorigenesis associated with chronic colitis in mice via apoptosis.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogens; Chemoprevention; Chronic Disease; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Intestinal Mucosa; Male; Mice; Mice, Inbred CBA; Sulindac; Water Supply | 2003 |
A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate.
Topics: Adenocarcinoma; Adenoma; Animals; Anticoagulants; Azoxymethane; beta Catenin; Carcinogens; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Dextran Sulfate; Disease Models, Animal; Inflammation; Injections, Intraperitoneal; Isoenzymes; Male; Mast Cells; Mice; Mice, Inbred ICR; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Trans-Activators; Tumor Suppressor Protein p53 | 2003 |
Sequential observations on the occurrence of preneoplastic and neoplastic lesions in mouse colon treated with azoxymethane and dextran sodium sulfate.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Immunoenzyme Techniques; Incidence; Injections, Intraperitoneal; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; Precancerous Conditions; Tyrosine | 2004 |
Beta-Catenin mutations in a mouse model of inflammation-related colon carcinogenesis induced by 1,2-dimethylhydrazine and dextran sodium sulfate.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Azoxymethane; beta Catenin; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Dextran Sulfate; Disease Models, Animal; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred ICR; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Trans-Activators | 2005 |
Dose-dependent promoting effect of dextran sodium sulfate on mouse colon carcinogenesis initiated with azoxymethane.
Topics: Animals; Azoxymethane; Carcinogens; Cocarcinogenesis; Colitis; Colonic Diseases; Colonic Neoplasms; Dextran Sulfate; Dose-Response Relationship, Drug; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; Tyrosine; Ulcer | 2005 |
In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy.
Topics: Animals; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Colonoscopes; Colonoscopy; Dextran Sulfate; Disease Models, Animal; Disease Progression; Intestinal Mucosa; Mice; Mice, Inbred Strains; Severity of Illness Index | 2005 |
Predisposition to colorectal cancer in rats with resolved colitis: role of cyclooxygenase-2-derived prostaglandin d2.
Topics: Animals; Azoxymethane; beta Catenin; Colitis; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Disease Susceptibility; Intramolecular Oxidoreductases; Lipocalins; Male; Prostaglandin D2; Rats; Rats, Wistar; Receptors, Immunologic; Receptors, Prostaglandin; Trinitrobenzenesulfonic Acid | 2005 |
Ursodeoxycholic acid versus sulfasalazine in colitis-related colon carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; RNA, Messenger; Sulfasalazine; Ursodeoxycholic Acid | 2007 |
Increased colonic inflammatory injury and formation of aberrant crypt foci in Nrf2-deficient mice upon dextran sulfate treatment.
Topics: Animals; Azoxymethane; Biomarkers; Colitis; Colon; Cytokines; Dextran Sulfate; Female; Gene Expression Regulation; Mice; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress | 2007 |
Insulin-like growth factor binding protein-3 inhibits colitis-induced carcinogenesis.
Topics: Animals; Azoxymethane; Colitis; Colonic Neoplasms; Disease Progression; Female; Follow-Up Studies; Insulin-Like Growth Factor Binding Protein 3; Mice; Mice, Transgenic; Neoplasms, Experimental; Treatment Outcome | 2007 |
Helicobacter hepaticus promotes azoxymethane-initiated colon tumorigenesis in BALB/c-IL10-deficient mice.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colitis; Colon; Colonic Neoplasms; Helicobacter hepaticus; Helicobacter Infections; Interleukin-10; Mice; Mice, Inbred BALB C; Mice, Knockout | 2008 |
Suppressive effects of nobiletin on hyperleptinemia and colitis-related colon carcinogenesis in male ICR mice.
Topics: Animals; Antioxidants; Azoxymethane; Carcinogens; Cell Division; Cell Line, Tumor; Colitis; Colonic Neoplasms; Flavones; Humans; Leptin; Male; Mice; Mice, Inbred ICR | 2008 |
5-aminosalicylic acid inhibits colitis-associated colorectal dysplasias in the mouse model of azoxymethane/dextran sulfate sodium-induced colitis.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; Mesalamine; Mice; Random Allocation | 2008 |
Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Bezafibrate; Cell Division; Chromans; Colitis; Colonic Neoplasms; Dextran Sulfate; Growth Substances; Intestinal Mucosa; Ligands; Male; Mucins; Muscle Proteins; Neuropeptides; Nucleolus Organizer Region; Peptides; Precancerous Conditions; Proteins; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Silver Staining; Thiazoles; Thiazolidinediones; Transcription Factors; Trefoil Factor-2; Trefoil Factor-3; Troglitazone | 2001 |
Troglitazone, a ligand for peroxisome proliferator-activated receptor gamma, inhibits chemically-induced aberrant crypt foci in rats.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Biogenic Polyamines; Carcinogens; Chromans; Colitis; Colonic Neoplasms; Dextran Sulfate; Intestinal Mucosa; Ligands; Male; Ornithine Decarboxylase; Precancerous Conditions; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2001 |