azoxymethane has been researched along with Carcinogenesis in 175 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 106 (60.57) | 24.3611 |
| 2020's | 69 (39.43) | 2.80 |
| Authors | Studies |
|---|---|
| Gong, W; Gu, G; Hong, Z; Liu, J; Liu, P; Ren, H; Ren, J; Wang, G; Wu, X; Zhao, F; Zhao, Y; Zheng, T | 1 |
| Allaman, MM; Asim, M; Barry, DP; Coburn, LA; Gobert, AP; Hardbower, DM; Piazuelo, MB; Polosukhina, D; Singh, K; Washington, MK; Wilson, KT | 1 |
| Canter, JA; Cao, L; Carlson, BA; Davis, CD; Ernst, SE; Gladyshev, VN; Grysczyk, L; Hatfield, DL; Peters, KM; Thielman, NRJ; Tsuji, PA; Udofe, P; Yu, Y | 1 |
| He, L; Li, W; Ma, Y; Sun, P; Wang, H; Zhang, X; Zhao, X | 1 |
| Chen, GQ; Chen, J; Li, Z; Liu, G; Wu, F; Zhang, S; Zhang, Y | 1 |
| Allaman, MM; Asim, M; Barry, DP; Coburn, LA; Delgado, AG; Finley, JL; Gobert, AP; Latour, YL; Luis, PB; McNamara, KM; Piazuelo, MB; Schneider, C; Sierra, JC; Singh, K; Smith, TM; Washington, MK; Wilson, KT; Zhao, S | 1 |
| Chen, IJ; Chen, YL; Cheng, KW; Cheng, TL; Chuang, CH; Ho, KW; Huang, BC; Huang, MY; Leu, YL; Lin, WW; Liu, HJ; Roffler, SR; Tseng, CH; Wang, JY | 1 |
| Ashby, J; Browning, DD; Hou, Y; Islam, BN; Li, H; Liu, K; Sharman, SK; Vega, KJ; Wang, R | 1 |
| Deng, J; Han, L; Li, Y; Shi, J; Wang, H; Yan, Y; Yuan, X; Zhang, H; Zhao, H; Zhao, L; Zhao, Y; Zou, F | 1 |
| Coker, OO; Kang, W; Li, C; Liu, C; Liu, D; Liu, Y; Sung, JJ; To, KF; Wang, Y; Wong, CC; Yu, J; Zhang, X; Zhou, Y | 1 |
| Eferl, R; Gushchina, V; Kallay, E; Kupper, N; Manhardt, T; Mesteri, I; Moritsch, S; Müller, C; Piatek, K; Salzmann, M; Schepelmann, M; Vlasaty, A | 1 |
| Chen, K; Gao, Z; Jia, H; Shi, Y; Wang, Z; Yuan, Y; Yue, T; Zeng, X | 1 |
| Cai, B; Chen, H; Guo, Y; Wang, X; Yao, Q; Ye, C; Zhang, F; Zhang, J; Zhang, Z | 1 |
| Chang, J; Geng, Z; Hao, X; Liu, J; Tan, X; Wang, Z; Yan, S | 1 |
| Kamakura, Y; Kawakami, S; Kojima, H; Kubota, A; Maeda, H; Miyashita, K; Murase, W; Mutoh, M; Ohta, T; Tanaka, T; Terasaki, M | 1 |
| Dong, S; Ismael, M; Lü, X; Shan, Y; Wang, T; Wang, X; Zheng, J | 1 |
| Begun, J; Davies, JM; Florin, TH; Giri, R; Hasnain, SZ; McGuckin, MA; Sheng, YH; Wang, R; Wong, KY; Yang, Y | 1 |
| Chen, Y; Diao, T; Li, D; Shang, G; Shi, L; Sun, L; Yin, X | 1 |
| Jeong, JH; Jo, HH; Kim, DH; Kim, DJ; Kim, EY; Kim, HJ; Lee, BJ; Lee, HJ; Lee, SH; Nam, SY; Park, YS; Seok, JH | 1 |
| Baker, K; Cotter, PD; Cronin, P; Gahan, CGM; Houston, A; Hyland, NP; Joyce, SA; Keane, JM; Melgar, S; Walsh, CJ | 1 |
| Bouznad, N; Brocker, T; Friedrich, V; Garzetti, D; Hermeking, H; Krebs, S; Krug, AB; Lutz, K; Matzek, D; Metzger, R; Öllinger, R; Rad, R; Rokavec, M; Schäfer, Y; Stecher, B; von Armansperg, B; Winheim, E; Winter, L | 1 |
| Bian, ZL; Chen, BQ; Chen, L; Chen, WJ; Cheng, TC; Feng, N; Ju, LL; Li, M; Liu, Y; Liu, YC; Liu, ZX; Luo, LL; Shao, JG; Wang, Y | 1 |
| Huang, XH; Jiang, B; Ni, M; Wang, L; Xu, YY; Zhang, QQ; Zhang, R; Zhang, YQ; Zhao, Q | 1 |
| An, SY; Kim, J; Kim, SW; Lee, DB; Pyo, SS; Yoon, DW | 1 |
| Jiang, Q; Jones-Hall, Y; Liu, KY; Nakatsu, CH; Wang, Q | 1 |
| Chen, C; El-Nezami, H; Ismaiah, MJ; Leung, HKM; Lo, EKK; Zhang, F | 1 |
| Kang, X; Kwong, TNY; Lam, TYT; Lin, Y; Liu, C; Ng, SK; Ni, Y; Sung, JJY; Wei, H; Wong, SH; Wu, WKK; Yu, J; Zhou, Y | 1 |
| Bullard, BM; Cardaci, TD; Fan, D; Hofseth, LJ; Huss, AR; McDonald, SJ; Murphy, EA; VanderVeen, BN | 1 |
| Chen, H; Fan, M; Fang, Y; Gou, H; Huang, Z; Li, X; Li, Y; Liu, D; Shang, H; Su, H; Wang, X; Wei, C; Wong, CC; Yu, J; Zeng, X; Zhang, X | 1 |
| Baccigalupi, L; Balestrieri, ML; Borrelli, F; Cacciola, NA; Campanile, C; Campanile, G; Cuozzo, M; D'Occhio, MJ; D'Onofrio, N; Maiolino, P; Martano, M; Neglia, G; Ricca, E; Russo, R; Saggese, A; Salzano, A; Venneri, T; Vinale, F | 1 |
| Horinaka, M; Ishikawa, H; Masuda, M; Morita, M; Mutoh, M; Nishimoto, E; Sakai, T; Yasuda, S | 1 |
| Chen, Y; Li, P; Liang, J; Luo, X; Wang, Q; Xie, X; Yang, C; Zhang, M; Zhou, L | 1 |
| Chen, X; Deng, Y; He, F; Huang, X; Tian, L; Wang, M; Yang, W; Yin, W; Zhou, H | 1 |
| Beck, S; Crossland, NA; Crott, JW; Guo, W; Lo, M; Mason, JB; Tan, WY; Zhang, C | 1 |
| Guo, M; Li, Z | 1 |
| Keleş, ÖF; Kömüroğlu, AU; Uyar, A; Yaman, T; Yener, Z | 1 |
| Oyama, T; Sugie, S; Tanaka, T | 1 |
| Gao, Y; Hammad, A; Namani, A; Shi, HF; Tang, X; Zheng, ZH | 1 |
| Ibuka, T; Kato, J; Kubota, M; Mizutani, T; Ohnishi, M; Sakai, H; Shimizu, M; Shirakami, Y; Tanaka, T | 1 |
| Deng, W; Gao, S; Guan, XY; He, HH; Huang, J; Li, C; Shay, JW; Wang, G; Wang, S; Wei, H; Wong, CC; Wong, SH; Yu, J; Zeng, Y; Zhai, J; Zhang, Y; Zhao, L; Zhou, Y | 1 |
| Chen, N; Cheng, L; Dai, L; Deng, H; Dong, Z; Fang, C; Fu, J; Ji, Y; Li, J; Liu, Y; Shi, G; Su, X; Wang, H; Wang, W; Yang, Y; Yu, Y; Zhang, H; Zhang, S | 1 |
| Deguchi, A; Kato, S; Kawanishi, S; Maebashi, U; Matsumoto, K; Morita, A; Motoyoshi, A; Nakahara, T; Nakamoto, T; Nishimura, K; Sueyoshi, M; Takata, K; Tominaga, M | 1 |
| Eun, CS; Han, DS; Jo, SV; Lee, AR; Lee, JG; Park, CH | 1 |
| Chen, D; Huang, Z; Liu, Y; Ma, H; Ouyang, G; Wang, J; Wu, T; Zhao, X | 1 |
| Berhow, M; Gonzalez de Mejia, E; Luna-Vital, D; Mazewski, C | 1 |
| Hong, JE; Hwang, S; Jo, M; Lee, CG; Park, CO; Rhee, KJ | 1 |
| Benninghoff, AD; Hintze, KJ; Hunter, AH; Monsanto, SP; Pestka, JJ; Phatak, S; Rodriguez, DM; Ward, RE; Wettere, AJV | 1 |
| Li, H; Li, Z; Shan, S; Shi, J; Yang, R; Zhang, C | 1 |
| Crott, JW; Kane, AV; Koh, GY; Wu, X | 1 |
| Huh, TG; Jeong, BJ; Jeong, JS; Kim, HY; Lee, JS; Park, KY; Song, JL | 1 |
| Bian, X; Fang, D; Jiang, X; Li, L; Li, Y; Lu, Y; Lv, L; Wang, K; Wang, Q; Wu, J; Wu, W; Xie, J; Yang, L; Ye, J | 1 |
| Bian, X; Chan, AWH; Chan, FKL; Coker, OO; El-Omar, E; Nakatsu, G; Sung, JJY; Wei, H; Wu, J; Yu, J; Zhao, L; Zhao, R; Zhou, Y | 1 |
| Lin, R; Liu, C; Piao, M; Song, Y | 1 |
| Diao, F; Li, X; Li, Y; Mei, Q; Niu, Y; Sun, Y; Zhou, H | 1 |
| Bars-Cortina, D; Macià, A; Martínez-Bardají, A; Motilva, MJ; Piñol-Felis, C | 1 |
| Alcalde, A; Arias, MA; Bird, PI; Camerer, E; Castro, M; Comas, L; Del Campo, R; Ferrandez, A; Galvez, EM; Garrido, M; Garzón, M; Gil-Gómez, G; Jaime-Sanchez, P; Lanuza, PM; Layunta, E; Martínez-Lostao, L; Metkar, S; Moreno, V; Muñoz, G; Pardo, J; Pelegrín, P; Peña, R; Ramirez-Labrada, A; Santiago, L; Sanz-Pamplona, R; Tapia, E; Uranga, JA; Uranga-Murillo, I | 1 |
| Ajani, JA; Anfossi, S; Bayraktar, R; Bhuvaneshwar, K; Burks, JK; Calin, GA; Chen, B; De Los Santos, MC; Dragomir, MP; Fabris, L; Ferracin, M; Fromm, B; Gagea, M; Girnita, L; Goel, A; Gusev, Y; Hanash, SM; Huo, L; Ivan, C; Ivkovic, TC; Katayama, H; Knutsen, E; Kopetz, S; Li, C; Li, Y; Ling, H; Liu, X; Matsuyama, T; Menter, D; Mimori, K; Multani, AS; Oki, E; Pardini, B; Parker-Thornburg, J; Reineke, LC; Sen, S; Shah, MY; Shen, P; Shimizu, M; Shimura, T; Slaby, O; Song, S; Syed, M; Taguchi, A; Tang, C; Uetake, H; Varani, G; Vasilescu, C | 1 |
| Feng, B; Lin, J; Lin, R; Liu, Z; Wu, H; Zhou, G | 1 |
| Abdelhady, HA; El-Gamal, MM; Mona, MM; Salim, EI | 1 |
| Bian, S; Liao, X; Wan, H; Wang, W | 1 |
| Bagni, C; Di Fusco, D; Di Grazia, A; Dinallo, V; Franzè, E; Laudisi, F; Marafini, I; Monteleone, G; Monteleone, I; Pedini, G; Rosina, E; Sica, G; Sileri, P; Stolfi, C | 1 |
| Abreu, MT; Brito, N; Burgueño, JF; Conner, GE; Davies, JM; Dheer, R; Diaz, S; Fernández, E; Fernández, I; Fritsch, J; González, EE; Hazime, H; Landau, KS; Phillips, MC; Pignac-Kobinger, J; Santander, AM; Santaolalla, R | 1 |
| Devaraj, H; Seetha, A; Sudhandiran, G | 1 |
| Fernández, J; Ferreira-Lazarte, A; Gallego-Lobillo, P; Lombó, F; Moreno, FJ; Villamiel, M; Villar, CJ | 1 |
| Bohnenberger, H; Meers, GK; Muzzi, C; Reichardt, HM; Reichardt, SD; Twomey, E; Watanabe, N | 1 |
| Im, S; Jiang, Q; Jones-Hall, Y; Nakatsu, C; Yang, C; Zhao, Y | 1 |
| Epifano, F; Fiorito, S; Genovese, S; Ibuka, T; Ideta, T; Kubota, M; Maruta, A; Miyazaki, T; Mizutani, T; Sakai, H; Shimizu, M; Shirakami, Y; Taddeo, VA; Tanaka, T | 1 |
| Chen, S; Chen, Y; Gao, J; Hou, S; Hu, J; Liang, J; Lin, J; Lu, Y; Wang, B; Yuan, X | 1 |
| Hiramoto, K; Kawanishi, S; Ma, N; Murata, M; Ohnishi, S; Wang, G; Yoshikawa, N | 1 |
| He, JM; Hu, JN; Liang, X | 1 |
| Ibuka, T; Ideta, T; Kochi, T; Kubota, M; Nakanishi, T; Ozawa, N; Sakai, H; Shimizu, M; Shirakami, Y; Tanaka, T | 1 |
| Elshaer, M; Hammad, A; Namani, A; Tang, X; Wang, XJ; Zheng, ZH | 1 |
| Chen, L; Liu, M; Meng, X; Ren, S; Sun, Q; Xu, H; Yang, H; Zeng, S; Zhao, H | 1 |
| Ali, DA; Arab, HH; Ashour, AM; Kabel, AM | 1 |
| Chen, C; Chen, J; Chen, R; Fang, L; Guo, C; Guo, D; Sang, T; Wang, X; Wang, Y; Wu, J | 1 |
| Berger, FG; Bridges, AE; Browning, DD; Hou, Y; Islam, BN; Kim, S; Kolhe, R; Rodriguez, PC; Sharman, SK; Singh, N; Sridhar, S; Trillo-Tinoco, J | 1 |
| Dai, X; Gui, G; Li, K; Liu, J; Xiao, Y; Yang, H | 1 |
| Bielawski, J; Chan, OTM; Furuya, H; Iino, K; Kawamori, T; Pagano, I; Shimizu, Y; Tamashiro, PM | 1 |
| He, L; Luan, Z; Lv, H; Qian, J; Tan, B; Wang, H; Xin, Y; Yang, H; Yu, S; Zhao, X; Zhou, W; Zhou, Y | 1 |
| Chang, EB; Du, W; He, TC; Huang, WH; Musch, MW; Wan, JY; Wang, CZ; Wang, Y; Williams, S; Yu, C; Yuan, CS; Zhang, CF | 1 |
| Alfwuaires, M; Alzahrani, AM; Bani Ismail, M; Hanieh, H; Ibrahim, HM; Mohafez, O; Shehata, T | 1 |
| Blackburn, C; Bulek, K; Carman, J; Chen, X; Hamilton, TA; Hao, Y; Huang, YH; Kalady, MF; Li, X; Liu, C; Ouyang, W; Su, B; Wang, X; Wang, Z; Wu, L; Yang, WP; Zepp, JA; Zhao, J; Zhu, J | 1 |
| Gao, L; Haraguchi, S; Ishida, F; Kim-Kaneyama, JR; Kudo, SE; Lei, XF; Li, S; Miyauchi, A; Miyazaki, A; Miyazaki, T; Nakahara, K; Ohnishi, K; Omoto, T; Orimo, A; Takeya, M; Tanaka, J; Umemoto, T; Yoshihara, K | 1 |
| Lin, JA; Wu, CH; Yen, GC | 1 |
| Cai, YK; Chen, J; Chen, WJ; Hao, Z; Lv, Y; Wang, HP; Wang, X; Ye, T; Zhao, JY | 1 |
| Chevillard-Briet, M; Escaffit, F | 1 |
| Allaman, MM; Asim, M; Barry, DP; Cleveland, JL; Coburn, LA; Delgado, AG; Gobert, AP; Luis, PB; Piazuelo, MB; Schneider, C; Shi, C; Singh, K; Washington, MK; Wilson, KT | 1 |
| Grill, JI; Herbst, A; Kolligs, FT; Marschall, MK; Neumann, J; Ofner, A; Wolf, E; Zierahn, H | 1 |
| Attaix, D; Blas-Y-Estrada, F; Blot, A; Chantelauze, C; Chevolleau, S; Corpet, DE; Debrauwer, L; Dupuy, J; Durand, D; Guéraud, F; Kuhnle, GGC; Martin, OCB; Meunier, N; Naud, N; Pierre, FHF; Pujos-Guillot, E; Santé-Lhoutellier, V; Sayd, T; Schlich, P; Scislowski, V; Taché, S; Urbano, C; Viala, D | 1 |
| Ahn, GO; Gu, H; Im, SH; Jeong, S; Kim, HJ; Kim, J; Kim, YE; Lee, M; Lee, YJ; Sung, YC; Weissman, IL; Yeo, S | 1 |
| Chastre, E; Jordan, P; Kotelevets, L; Lehy, T; Mamadou, G; Walker, F | 1 |
| Bianco, G; Caruso, MG; D'Alessandro, R; DE Nunzio, V; Gigante, I; Messa, C; Notarnicola, M; Refolo, MG; Scavo, MP; Tafaro, A; Tutino, V | 1 |
| Choi, JH; Park, KY; Seo, JH; Song, JL | 1 |
| Almoghrabi, A; Backman, V; Bissonnette, M; Dougherty, U; Eshein, A; Gomes, A; Hart, J; Konda, V; Pabla, B; Roy, HK; Ruderman, S; Singh, A; Valuckaite, V | 1 |
| Booth, CJ; D'Souza, SS; Kartchner, BJ; Lee, EC; Malizia, RA; O'Connor, W; Sharp, SP; Stain, SC; Walrath, T | 1 |
| Cui, K; Li, M; Li, Y; Lin, H; Shu, HB; Wang, SY; Wang, YY; Xia, T; Xu, ZS; Zhang, HX | 1 |
| Álvarez-González, I; Baltiérrez-Hoyos, R; Dávila-Ortiz, G; Garduño-Siciliano, L; Jiménez Martínez, C; León-Espinosa, EB; Madrigal-Bujaidar, E; Sánchez-Chino, XM; Vásquez-Garzón, VR | 1 |
| Balboa, MA; Balsinde, J; Cubero, Á; García-Rostán, G; Győrffy, B; Lordén, G; Meana, C; Orduña, A; Peña, L | 1 |
| Masuda, J; Seko, T; Umemura, C; Yamashita, M; Yamashita, Y; Yamauchi, K; Yokozawa, M | 1 |
| Aleksandersen, M; Berntsen, HF; Hansen, KEA; Johanson, SM; Paulsen, JE; Ropstad, E; Steppeler, C; Sødring, M; Zimmer, KE; Østby, GC | 1 |
| Campanholo, VMLP; Forones, NM; Ribeiro Paiotti, AP; Ribeiro, CCD; Ribeiro, DA; Silva, RM | 1 |
| Al-Attabi, Z; Al-Malky, RN; Al-Maskari, SNM; Al-Ruqaishi, BRS; Ali, A; Deth, RC; Dong, J; Guizani, N; Padmanabhan, S; Rahman, MS; Taranikanti, V; Waly, MI | 1 |
| Hwang, S; Khalmuratova, R; Kim, JH; Kim, YS; Koh, SJ; Lee, GY; Lee, M; Park, JW; Shin, HW; Yoon, DW | 1 |
| Huang, G; Li, B; Lu, J; Ma, L; Su, J; Wang, Y; Xu, Y; Yin, L | 1 |
| Han, W; Li, W; Lv, X; Wang, H; Zhao, X | 1 |
| Bissonnette, M; Chen, CT; Chen, NT; Dougherty, U; Hart, J; Lo, LW; Souris, JS; Waller, JV; Zhang, HJ | 1 |
| Chen, J; Du, RL; Gu, B; Li, SZ; Pan, WM; Song, Y; Xiang, Y; Zhang, HH; Zhang, XD; Zhao, H | 1 |
| Bensard, C; Chen, X; Rutter, J; Schell, JC; Swanson, E; Tantin, D; Vázquez-Arreguín, K | 1 |
| Angelou, A; Antoniou, E; Buettner, S; Faateh, M; Margonis, GA; Papalois, AE; Pikouli, A; Pikoulis, E; Theocharis, S; Theodoropoulos, G; Ventin, M; Wang, J; Zografos, GC | 1 |
| Biemond, I; D'Haens, G; de Jonge-Muller, ES; Ederveen, A; Groothuis, P; Hardwick, JC; Heijmans, J; Hommes, DW; Muncan, V; Roelofs, J; Rosekrans, SL; van den Brink, GR; van Lidth de Jeude, JF; Wielenga, MC | 1 |
| Fitch, MD; Fleming, SE; Sikalidis, AK | 1 |
| Imai, T; Ishigamori, R; Ito, K; Mutoh, M; Ohta, T; Takahashi, M | 1 |
| Cooma, I; Kawamori, T; Patlolla, JM; Rao, CV; Steele, VE | 1 |
| Ahmed, I; Anant, S; Chandrakesan, P; Houchen, C; Jakkula, LU; Papineni, R; Ramamoorthy, P; Roy, B; Tawfik, O; Umar, S | 1 |
| Barth, SW; Bousserouel, S; Gossé, F; Le Grandois, J; Marchioni, E; Marescaux, J; Raul, F; Werner, D | 1 |
| Barrett, CW; Bradley, AM; Burk, RF; Chaturvedi, R; Davies, SS; Fingleton, BM; Hill, KE; Lintel, MK; Matafonova, E; Motley, AK; Ning, W; Parang, B; Poindexter, SV; Reddy, VK; Singh, K; Washington, MK; Williams, CS; Wilson, KT | 1 |
| Brigelius-Flohé, R; Chu, FF; Esworthy, RS; Florian, S; Kipp, AP; Müller, MF; Osterhoff, M; Pommer, S | 1 |
| Backman, V; Crawford, SE; Damania, DP; DelaCruz, M; Kunte, DP; Roy, HK; Subramanian, H; Tiwari, AK; Wali, RK | 1 |
| Daikoku, T; Dey, SK; Dubois, RN; Katoh, H; Sun, H; Wang, D | 1 |
| Borrelli, F; Cascio, MG; Izzo, AA; Pagano, E; Pertwee, RG; Romano, B | 1 |
| Arcangeli, A; Caderni, G; Carraresi, L; De Lorenzo, E; Femia, AP; Fiore, A; Fortunato, A; Lastraioli, E; Morabito, A; Polvani, S | 1 |
| Bours, V; Bouznad, N; Delvenne, P; Geurts, P; Hego, A; Huynh-Thu, VA; Irrthum, A; Josse, C; Oury, C; Servais, L | 1 |
| Arber, N; Avivi, D; Kazanov, D; Kraus, S; Naumov, I; Rosin-Arbesfeld, R; Shapira, S; Zilberberg, A | 1 |
| MacFarlane, AJ; McEntee, MF; Stover, PJ | 1 |
| Al Riyami, M; Al-Alawi, A; Al-Issaei, HK; Al-Kindi, MA; Al-Rawahi, AS; Farooq, SA; Rahman, MS; Waly, MI | 1 |
| Cichello, SA; Duan, JL; He, XQ; Zhou, J | 1 |
| Colburn, NH; Hou, W; Hua, B; Jia, L; Li, W; Lin, H; Matter, MS; Saud, SM; Young, MR | 1 |
| Acosta-Gallegos, J; Campos-Vega, R; Feregrino-Perez, AA; Gomez-Arbones, X; Guevara-González, RG; Loarca-Piña, G; Piñol-Felis, C | 1 |
| Alam, F; Byun, Y; Chung, SW; Jeon, OC; Kim, JY; Kim, SY; Park, J; Son, WC | 1 |
| Chang, HK; Kang, SA; Kim, HY; Park, KY; Song, JL | 1 |
| Hosono, A; Seki, T; Takai, S; Yamaguchi, M | 1 |
| Esa, NM; Hamzah, H; Karim, R; Rahman, HS; Tan, BL | 1 |
| Barton, JK; Leung, SJ; Rice, PS | 1 |
| Ahn, J; Barber, GN; Konno, H | 1 |
| Abdella, EM; El-Derby, AM; Mahmoud, AM | 1 |
| Jiang, T; Long, M; Park, SL; Rojo de la Vega, M; Tao, S; Wen, Q; Wondrak, GT; Zhang, DD | 1 |
| He, X; He, Z; Hu, J; Ke, J; Lan, P; Li, S; Lian, L; Sun, L; Wu, X; Zou, Y | 1 |
| Deng, Z; Egilmez, NK; Guo, H; Haribabu, B; Miller, D; Mu, J; Norris, J; Tseng, M; Wang, Q; Wattenberg, B; Yan, J; Zhang, HG; Zhang, L; Zhuang, X | 1 |
| Fukui, T; Kishimoto, M; Mitsuyama, T; Miyamoto, S; Nishio, A; Okazaki, K; Sakaguchi, Y; Suzuki, R; Takahashi, Y; Takeo, M; Uchida, K | 1 |
| Baloghova, N; Dobes, J; Dubuissez, M; Fafilek, B; Galuskova, K; Hlavata, A; Horazna, M; Janeckova, L; Korinek, V; Leprince, D; Pospichalova, V; Sloncova, E; Stancikova, J; Strnad, H; Tureckova, J; Vojtechova, M | 1 |
| Cai, Y; Golla, JP; Golla, S; Gonzalez, FJ; Korboukh, I; Krausz, KW; Manna, SK; Matsubara, T; Takahashi, S; Tanaka, N | 1 |
| Byun, SY; Kim, DB; Kim, E | 1 |
| Fukushima, T; Haruyama, Y; Itoh, H; Kanemaru, A; Kangawa, K; Kataoka, H; Kawaguchi, M; Matsumoto, N; Nakazato, M; Tanaka, H; Yamamoto, K | 1 |
| Cho, YH; Choi, CY; Choi, KY; Di Paolo, G; Kang, DW; Min, do S; Tian, H | 1 |
| Abdulla, MA; Emtyazjoo, M; Hajrezaie, M; Hassandarvish, P; Karimian, H; Majid, NA; Moghadamtousi, SZ; Mohd Ali, H; Shams, K; Zahedifard, M | 1 |
| Mellem, J; Naicker, T; Odun-Ayo, F; Reddy, L | 1 |
| Hazilawati, H; Huynh, K; Norhaizan, ME; Roselina, K; Tan, BL; Yeap, SK | 1 |
| Dammann, K; Evstatiev, R; Gasche, C; Harpain, F; Khare, V; Kurtovic, A; Lang, M; Mesteri, I | 1 |
| Agarwal, R; Charepalli, V; Radhakrishnan, S; Reddivari, L; Vadde, R; Vanamala, JK | 1 |
| Cichello, SA; Duan, JL; He, XQ; Song, ZY; Zhou, J | 1 |
| Chinikaylo, A; Chittur, SV; Gutierrez, LS; Lawler, J; Lippert, B; Lopez-Dee, ZP; Patel, B; Patel, H | 1 |
| Kim, H; Lee, HA; Lee, KW; Park, KY | 1 |
| Akatsu, M; Hara, S; Ishii, T; Ishikawa, Y; Kamiyama, A; Kamiyama, S; Kuwata, H; Matsumoto, K; Nakatani, Y; Sasaki, Y; Yokoyama, C | 1 |
| Chien, SP; Liu, CT; Liu, MY; Periasamy, S; Wu, WH | 1 |
| Brickey, WJ; Ding, S; Hu, P; Jobin, C; Koblansky, AA; Li, Z; Liu, R; Lund, PK; McFadden, RM; Montgomery, SA; Mühlbauer, M; Ting, JP; Truax, AD; Wilson, JE | 1 |
| Chen, YK; Ma, J; Qi, J; Xu, Y; Yuan, W | 1 |
| Henjum, K; Hetland, RB; Knutsen, SH; Måge, I; Moen, B; Paulsen, JE; Rud, I | 1 |
| Chen, Y; Miyamoto, S; Nakanishi, M; Qendro, V; Rosenberg, DW; Weinstock, E; Weinstock, GM | 1 |
| Anderson, S; Calway, T; Chen, L; Jia, W; Qiu, Y; Wang, CZ; Wang, Y; Wen, XD; Yu, C; Yuan, CS; Zhang, CF; Zhang, Z | 1 |
| Almer, S; Bergström, Å; Blaas, L; Büller, NV; Englert, B; Fredlund, E; Frings, O; Gerling, M; Joost, S; Kirn, LM; Kühl, AA; Kuiper, RV; Toftgård, R; van den Brink, GR; Wielenga, MC | 1 |
| Adam, A; Büttner, R; Dietlein, F; Ermolaeva, MA; Fernández-Majada, V; Komander, D; Pasparakis, M; Schell, M; Schumacher, B; Thomas, RK; Welz, PS | 1 |
| Goto, N; Inoue, T; Kashimoto, S; Kukimoto-Niino, M; Masuda, M; Mimata, A; Moriyama, H; Ohata, H; Ohbayashi, N; Okamoto, K; Sawa, M; Shirouzu, M; Uno, Y; Yamada, T | 1 |
| Cao, L; Gao, L; Huo, X; Li, L; Liu, D | 1 |
| Elewaut, D; Filtjens, J; Kerre, T; Leclercq, G; Louagie, E; Plum, J; Taghon, T; Taveirne, S; Van Acker, A; Van Ammel, E; Vandekerckhove, B | 1 |
| Bader, JE; Carson, JA; Carson, MS; Chatzistamou, I; Cranford, TL; Davis, JM; Enos, RT; Murphy, EA; Nagarkatti, M; Nagarkatti, PS; Singh, UP; Velázquez, KT | 1 |
| Aleynikova, O; Beauchemin, N; Li, N; Ngo, CT; Richard, S | 1 |
| Do, SG; Im, SA; Kim, HS; Kim, JW; Lee, CK; Park, CS; Park, YI; Shin, E | 1 |
| Han, J; Ishibashi, R; Kato, N; Kishikawa, T; Koike, K; Miyazawa, M; Nakagawa, R; Ohno, M; Otsuka, M; Suzuki, N; Takata, A; Wu, J; Yamagami, M; Yoshikawa, T | 1 |
| Allred, CD; Callaway, ES; Chapkin, RS; Davidson, LA; Hensel, ME; Jayaprakasha, GK; Kim, E; Patil, BS; Salinas, ML; Turner, ND; Weeks, BR; Zoh, RS | 1 |
| Ahmad, J; El-Shemi, AG; Idris, S; Kensara, OA; Mohamed, AM; Refaat, B | 1 |
| Cai, S; Gao, R; Goel, A; Guo, B; Hong, L; Li, H; Liu, M; Ma, Y; Moyer, MP; Pan, C; Peng, J; Qin, H; Toiyama, Y; Wang, P; Wei, Q; Weng, W; Yang, L; Yang, Y; Yin, M; Zhu, Q | 1 |
| Choi, YJ; Kim, N; Lee, DH; Lee, HN; Lee, HS; Lee, S; Nam, RH; Surh, YJ | 1 |
| Inoue, M; Ishihara, A; Okamoto, Y; Tokumura, A; Tsutsumi, T | 1 |
| Cai, X; Gao, Z; Li, F; Qiu, P; Rakariyatham, K; Song, M; Wang, M; Wu, X; Xiao, H; Xu, F; Zheng, J | 1 |
| de Villena, FP; Hua, K; Jung, KC; Kelly, SA; Kim, Y; Pomp, D; Threadgill, DW; Zhao, L | 1 |
1 trial(s) available for azoxymethane and Carcinogenesis
| Article | Year |
|---|---|
Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption.
Topics: Adult; Animals; Azoxymethane; Biomarkers; Carcinogenesis; Carcinogens; Colonic Neoplasms; Cooking; Cross-Over Studies; Feces; Female; Healthy Volunteers; Heme; Humans; Lipid Peroxidation; Male; Mice; Middle Aged; Neoplasms, Experimental; Rats; Rats, Inbred F344; Red Meat | 2018 |
174 other study(ies) available for azoxymethane and Carcinogenesis
| Article | Year |
|---|---|
STING-mediated Syk Signaling Attenuates Tumorigenesis of Colitis‑associated Colorectal Cancer Through Enhancing Intestinal Epithelium Pyroptosis.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Pyroptosis; Syk Kinase | 2022 |
CCL11 exacerbates colitis and inflammation-associated colon tumorigenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Chemokine CCL11; Colitis; Colitis-Associated Neoplasms; Epithelial Cells; Mice; Mice, Knockout | 2021 |
Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogenesis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Diet; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Intestinal Mucosa; Male; Mice; Mice, Knockout; Selenoproteins; Signal Transduction; Sodium Selenite; Trace Elements | 2021 |
High-fat diet aggravates colitis-associated carcinogenesis by evading ferroptosis in the ER stress-mediated pathway.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Dextran Sulfate; Diet, High-Fat; Disease Models, Animal; Ferroptosis; Mice; Mice, Inbred C57BL | 2021 |
Applications and Mechanism of 3-Hydroxybutyrate (3HB) for Prevention of Colonic Inflammation and Carcinogenesis as a Food Supplement.
Topics: 3-Hydroxybutyric Acid; Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL | 2021 |
Protective Role of Spermidine in Colitis and Colon Carcinogenesis.
Topics: Adenomatous Polyposis Coli Protein; alpha-Defensins; Animals; Azoxymethane; Carcinogenesis; Colitis; Colitis, Ulcerative; Colon; Colonic Neoplasms; Dextran Sulfate; Gastrointestinal Microbiome; Gene Expression Regulation; Humans; Intestinal Mucosa; Male; Mice; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Precancerous Conditions; Protective Factors; RNA, Messenger; Severity of Illness Index; Spermidine; Weight Loss | 2022 |
Inhibition of gut microbial β-glucuronidase effectively prevents carcinogen-induced microbial dysbiosis and intestinal tumorigenesis.
Topics: Animals; Azoxymethane; Bacteria; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Colorectal Neoplasms; Dysbiosis; Gastrointestinal Microbiome; Glucuronidase; Mice | 2022 |
Type-2 cGMP-dependent protein kinase suppresses proliferation and carcinogenesis in the colon epithelium.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Colon; Colonic Neoplasms; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type II; Dextran Sulfate; Epithelium; Mice; Mice, Inbred C57BL; Mice, Knockout | 2022 |
Pre-Administration of Berberine Exerts Chemopreventive Effects in AOM/DSS-Induced Colitis-Associated Carcinogenesis Mice via Modulating Inflammation and Intestinal Microbiota.
Topics: Animals; Azoxymethane; Berberine; Carcinogenesis; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Mice; Mice, Inbred C57BL; RNA, Ribosomal, 16S | 2022 |
Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis.
Topics: Animals; Azoxymethane; Bile Acids and Salts; Carcinogenesis; Cell Proliferation; Cholesterol; Colorectal Neoplasms; Dysbiosis; Fluorouracil; Mice; Occludin; Oxaliplatin; RNA, Messenger; Squalene Monooxygenase; Terbinafine | 2022 |
AOM/DSS Induced Colitis-Associated Colorectal Cancer in 14-Month-Old Female Balb/C and C57/Bl6 Mice-A Pilot Study.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinoma; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pilot Projects | 2022 |
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Kefir; Lactobacillus; Mice; RNA, Ribosomal, 16S; Saccharomyces cerevisiae; Tibet | 2022 |
Berberine inhibits intestinal carcinogenesis by suppressing intestinal pro-inflammatory genes and oncogenic factors through modulating gut microbiota.
Topics: Animals; Azoxymethane; Berberine; Carcinogenesis; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Mice; Mice, Inbred C57BL; NF-kappa B; RNA, Ribosomal, 16S | 2022 |
Berberine regulates short-chain fatty acid metabolism and alleviates the colitis-associated colorectal tumorigenesis through remodeling intestinal flora.
Topics: Animals; Azoxymethane; Berberine; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Fatty Acids, Volatile; Gastrointestinal Microbiome; Interleukin-6; Lipopolysaccharides; Mice; Mice, Inbred C57BL; NF-kappa B; Occludin; Tandem Mass Spectrometry; Toll-Like Receptor 4 | 2022 |
A Biscuit Containing Fucoxanthin Prevents Colorectal Carcinogenesis in Mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Mice; Xanthophylls | 2022 |
Lacticaseibacillus rhamnosus LS8 Ameliorates Azoxymethane/Dextran Sulfate Sodium-Induced Colitis-Associated Tumorigenesis in Mice via Regulating Gut Microbiota and Inhibiting Inflammation.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Dextran Sulfate; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Lacticaseibacillus rhamnosus; Mice | 2022 |
MUC1-mediated Macrophage Activation Promotes Colitis-associated Colorectal Cancer via Activating the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Axis.
Topics: Animals; Azoxymethane; Carcinogenesis; Chemotactic Factors; Colitis; Colitis-Associated Neoplasms; Colonic Neoplasms; Dextran Sulfate; Interleukin-6; Macrophage Activation; Mice; Mice, Knockout; Mucin-1; STAT3 Transcription Factor | 2022 |
Aspirin Inhibits Carcinogenesis of Intestinal Mucosal Cells in UC Mice Through Inhibiting IL-6/JAK/STAT3 Signaling Pathway and Modulating Apoptosis and Proliferation.
Topics: Animals; Apoptosis; Aspirin; Azoxymethane; Carcinogenesis; Cell Proliferation; Colitis, Ulcerative; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Hyperplasia; Inflammation; Interleukin-10; Interleukin-6; Janus Kinases; Mice; Proliferating Cell Nuclear Antigen; Signal Transduction; STAT3 Transcription Factor | 2022 |
Epigallocatechin-3-gallate suppresses hemin-aggravated colon carcinogenesis through Nrf2-inhibited mitochondrial reactive oxygen species accumulation.
Topics: Animals; Antioxidants; Azoxymethane; Caco-2 Cells; Carcinogenesis; Catechin; Cell Cycle Proteins; Colon; Dextrans; Hemin; Humans; Iron; Kelch-Like ECH-Associated Protein 1; Lactate Dehydrogenases; Malondialdehyde; Mice; NF-E2-Related Factor 2; Reactive Oxygen Species; Rodent Diseases; Tea; Tetrazolium Salts | 2022 |
Investigation of the gut microbiome, bile acid composition and host immunoinflammatory response in a model of azoxymethane-induced colon cancer at discrete timepoints.
Topics: Animals; Azoxymethane; Bile Acids and Salts; Carcinogenesis; Chromatography, Liquid; Colon; Colonic Neoplasms; Disease Models, Animal; Gastrointestinal Microbiome; Mice; RNA, Ribosomal, 16S; Tandem Mass Spectrometry | 2023 |
CCL17 Promotes Colitis-Associated Tumorigenesis Dependent on the Microbiota.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Chemokine CCL17; Colitis; Colonic Neoplasms; Gastrointestinal Microbiome; Mice | 2022 |
Interleukin-34 deficiency aggravates development of colitis and colitis-associated cancer in mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colitis-Associated Neoplasms; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Interleukins; Mice | 2022 |
Ginsenoside Rb1 Suppresses AOM/DSS-induced Colon Carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colorectal Neoplasms; Disease Models, Animal; Ginsenosides; Inflammation; Mice; Mice, Inbred C57BL; Tumor Microenvironment | 2023 |
Sleep Fragmentation Accelerates Carcinogenesis in a Chemical-Induced Colon Cancer Model.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Sleep Deprivation | 2023 |
Combining gamma-tocopherol and aspirin synergistically suppresses colitis-associated colon tumorigenesis and modulates the gut microbiota in mice, and inhibits the growth of human colon cancer cells.
Topics: Animals; Aspirin; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; gamma-Tocopherol; Gastrointestinal Microbiome; Humans; Mice; Mice, Inbred C57BL | 2023 |
Zearalenone attenuates colitis associated colorectal tumorigenesis through Ras/Raf/ERK pathway suppression and SCFA-producing bacteria promotion.
Topics: Animals; Azoxymethane; Bacteria; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Humans; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Zearalenone | 2023 |
Altered gut microbiota of obesity subjects promotes colorectal carcinogenesis in mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Colonic Neoplasms; Colorectal Neoplasms; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Mice; Mice, Inbred C57BL; Obesity | 2023 |
Panaxynol alleviates colorectal cancer in a murine model via suppressing macrophages and inflammation.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mucins | 2023 |
Traditional Medicine Pien Tze Huang Suppresses Colorectal Tumorigenesis Through Restoring Gut Microbiota and Metabolites.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogenesis; Colorectal Neoplasms; Dextran Sulfate; Gastrointestinal Microbiome; Medicine, Traditional; Mice; Phosphatidylinositol 3-Kinases; Signal Transduction | 2023 |
Chemopreventive effect of a milk whey by-product derived from Buffalo (Bubalus bubalis) in protecting from colorectal carcinogenesis.
Topics: Animals; Azoxymethane; Buffaloes; Butyric Acid; Carcinogenesis; Colorectal Neoplasms; Humans; Mice; Milk; Whey | 2023 |
Discovery of cancer-preventive juices reactivating RB functions.
Topics: Animals; Antioxidants; Apoptosis; Azoxymethane; Carcinogenesis; Humans; Neoplasms; Rats | 2023 |
Astragaloside IV inhibits AOM/DSS-induced colitis-associated tumorigenesis via activation of PPARγ signaling in mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Dextran Sulfate; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; PPAR gamma; Reactive Oxygen Species | 2023 |
Chemopreventive Effects of Polysaccharides and Flavonoids from Okra Flowers in Azomethane/Dextran Sulfate Sodium-Induced Murine Colitis-Associated Cancer.
Topics: Abelmoschus; Animals; Anticarcinogenic Agents; Azoxymethane; beta Catenin; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Flavonoids; Hominidae; Humans; Interleukin-6; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt | 2023 |
Fecal microbiota transplanted from old mice promotes more colonic inflammation, proliferation, and tumor formation in azoxymethane-treated A/J mice than microbiota originating from young mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Colonic Neoplasms; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Inflammation; Mice; Microbiota | 2023 |
Polysaccharides isolated from Nostoc commune Vaucher inhibit colitis-associated colon tumorigenesis in mice and modulate gut microbiota.
Topics: Animals; Azoxymethane; Bacteria; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Fatty Acids, Volatile; Feces; Gastrointestinal Microbiome; Male; Mice; Mice, Inbred C57BL; Nostoc commune; Polysaccharides; RNA, Ribosomal, 16S | 2019 |
Chemopreventive efficacy of juniper berry oil (
Topics: Animals; Azoxymethane; Carcinogenesis; Colon; Colonic Neoplasms; Juniperus; Male; Plant Oils; Rats; Rats, Wistar | 2021 |
Dietary Tricin Suppresses Inflammation-Related Colon Carcinogenesis in Mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Diet; Flavonoids; Male; Mice; Tumor Necrosis Factor-alpha | 2019 |
Identification of novel Nrf2 target genes as prognostic biomarkers in colitis-associated colorectal cancer in Nrf2-deficient mice.
Topics: Animals; Azoxymethane; Biomarkers; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Signal Transduction | 2019 |
Suppressive effects of the sodium‑glucose cotransporter 2 inhibitor tofogliflozin on colorectal tumorigenesis in diabetic and obese mice.
Topics: Animals; Azoxymethane; Benzhydryl Compounds; Blood Glucose; Carcinogenesis; Cell Proliferation; Colorectal Neoplasms; Diabetes Mellitus, Type 2; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Hypoglycemic Agents; Mice; Mice, Inbred NOD; Mice, Obese; Obesity; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Tumor Necrosis Factor-alpha | 2019 |
MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer.
Topics: Aneuploidy; Animals; Apoptosis; Azoxymethane; Carcinogenesis; Carcinogens; Cell Proliferation; Chromosomal Instability; Colorectal Neoplasms; Humans; Mice; Mice, Knockout; Microtubule-Associated Proteins; Mitosis; Prognosis; Survival Rate; Tumor Cells, Cultured | 2020 |
Temporal DNA methylation pattern and targeted therapy in colitis-associated cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Azoxymethane; bcl-Associated Death Protein; Carcinogenesis; Cell Line, Tumor; Colitis; Colon; Colonoscopy; Colorectal Neoplasms; Decitabine; Disease Models, Animal; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Male; Mice; Molecular Targeted Therapy; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Up-Regulation | 2020 |
Role of transient receptor potential vanilloid subtype 4 in the regulation of azoymethane/dextran sulphate sodium-induced colitis-associated cancer in mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Cell Proliferation; Chemokine CXCL2; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Progression; Human Umbilical Vein Endothelial Cells; Humans; Intestinal Mucosa; Macrophages; Male; Mice; Mice, Knockout; Neoplasms, Experimental; TRPV Cation Channels | 2020 |
The impact of gut microbiota manipulation with antibiotics on colon tumorigenesis in a murine model.
Topics: Animals; Anti-Bacterial Agents; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Microbiome; High-Throughput Nucleotide Sequencing; Inflammation; Mice; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Tumor Burden | 2019 |
Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation.
Topics: Adaptor Proteins, Signal Transducing; Adenomatous Polyposis Coli; Animals; Azoxymethane; Carcinogenesis; Cell Adhesion Molecules; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Focal Adhesion Protein-Tyrosine Kinases; Humans; Inflammation; Integrins; Interleukin-6; Intestines; Mice, Inbred C57BL; Myofibroblasts; Precancerous Conditions; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Stromal Cells; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins | 2020 |
Reduction of colitis-associated colon carcinogenesis by a black lentil water extract through inhibition of inflammatory and immunomodulatory cytokines.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Fabaceae; Gene Expression Profiling; Inflammation; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Water | 2020 |
Protective Effects of Zerumbone on Colonic Tumorigenesis in Enterotoxigenic
Topics: Administration, Oral; Animals; Azoxymethane; Bacteroides fragilis; Body Weight; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Female; Mice; Mice, Inbred BALB C; Protective Agents; Sesquiterpenes; Severity of Illness Index | 2020 |
Consumption of the Total Western Diet Promotes Colitis and Inflammation-Associated Colorectal Cancer in Mice.
Topics: Adaptive Immunity; Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Diet, Western; Disease Models, Animal; Immunity, Innate; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; RNA, Messenger | 2020 |
Inhibitory Effects of Bound Polyphenol from Foxtail Millet Bran on Colitis-Associated Carcinogenesis by the Restoration of Gut Microbiota in a Mice Model.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colorectal Neoplasms; Dextran Sulfate; Ecosystem; Gastrointestinal Microbiome; Mice; Mice, Nude; Polyphenols; RNA, Ribosomal, 16S; Setaria Plant | 2020 |
Parabacteroides distasonis attenuates tumorigenesis, modulates inflammatory markers and promotes intestinal barrier integrity in azoxymethane-treated A/J mice.
Topics: Animals; Azoxymethane; Bacteroidetes; Carcinogenesis; Colon; Colonic Neoplasms; Humans; Inflammation; Interleukin-4; Intestinal Mucosa; Mice; Obesity; Signal Transduction; Toll-Like Receptor 4; Transforming Growth Factor beta | 2020 |
Dietary Mixed Cereal Grains Ameliorate the Azoxymethane and Dextran Sodium Sulfate-Induced Colonic Carcinogenesis in C57BL/6J Mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Caspase 3; Colon; Colonic Neoplasms; Colorectal Neoplasms; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Dietary Carbohydrates; Disease Models, Animal; Edible Grain; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; RNA, Messenger; Tumor Necrosis Factors; Tumor Suppressor Protein p53 | 2020 |
Administration of Bifidobacterium bifidum CGMCC 15068 modulates gut microbiota and metabolome in azoxymethane (AOM)/dextran sulphate sodium (DSS)-induced colitis-associated colon cancer (CAC) in mice.
Topics: Animals; Azoxymethane; Bifidobacterium bifidum; Carcinogenesis; Colitis-Associated Neoplasms; Dextran Sulfate; Disease Models, Animal; Feces; Gastrointestinal Microbiome; Male; Metabolome; Mice; Mice, Inbred C57BL; Probiotics | 2020 |
Aspirin Reduces Colorectal Tumor Development in Mice and Gut Microbes Reduce its Bioavailability and Chemopreventive Effects.
Topics: Adenomatous Polyposis Coli Protein; Animals; Anti-Bacterial Agents; Anticarcinogenic Agents; Aspirin; Azoxymethane; Bacillaceae; Bacteroides fragilis; Bacteroidetes; Biological Availability; Carcinogenesis; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; DNA, Bacterial; Dose-Response Relationship, Drug; Feces; Gastrointestinal Microbiome; Germ-Free Life; Humans; Intestinal Mucosa; Male; Mice; Mice, Transgenic; RNA, Ribosomal, 16S | 2020 |
Quercetin Suppresses AOM/DSS-Induced Colon Carcinogenesis through Its Anti-Inflammation Effects in Mice.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Biomarkers, Tumor; Carcinogenesis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Gentian Violet; Humans; Hydroxybutyrates; Mice; Mice, Inbred C57BL; Oxidative Stress; Quercetin; Tumor Burden | 2020 |
Apple polysaccharide prevents from colitis-associated carcinogenesis through regulating macrophage polarization.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Macrophages; Male; Malus; Mice; Mice, Inbred ICR; Polysaccharides; RAW 264.7 Cells; Signal Transduction; Toll-Like Receptor 4 | 2020 |
Consumption evaluation of one apple flesh a day in the initial phases prior to adenoma/adenocarcinoma in an azoxymethane rat colon carcinogenesis model.
Topics: Adenocarcinoma; Animals; Anthocyanins; Azoxymethane; Carcinogenesis; Colonic Neoplasms; Flavonoids; Fruit; Galactosides; Humans; Male; Malus; Plant Extracts; Polyphenols; Rats; Rats, Wistar | 2020 |
Extracellular Granzyme A Promotes Colorectal Cancer Development by Enhancing Gut Inflammation.
Topics: Acute Disease; Animals; Azoxymethane; Carcinogenesis; Chronic Disease; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Disease Progression; Extracellular Space; Granzymes; Humans; Inflammasomes; Inflammation; Inflammation Mediators; Interleukin-6; Mice, Knockout; NF-kappa B; RNA, Messenger | 2020 |
The Long Noncoding RNA CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase B; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Chromosomal Instability; Colon; Colorectal Neoplasms; Cytogenetic Analysis; Dextrans; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Intestinal Mucosa; Male; Mice; Mice, Transgenic; Neoplasms, Experimental; Organoids; Primary Cell Culture; Proto-Oncogene Proteins c-myc; RNA-Binding Proteins; RNA, Long Noncoding; Signal Transduction | 2020 |
TRIM21 Is Decreased in Colitis-associated Cancer and Negatively Regulates Epithelial Carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis-Associated Neoplasms; Colitis, Ulcerative; Cytokines; Dextran Sulfate; Humans; Mice; Mice, Knockout; Ribonucleoproteins; Tissue Adhesions | 2021 |
Attenuation of Rat Colon Carcinogenesis by Styela plicata Aqueous Extract. Modulation of NF-κB Pathway and Cytoplasmic Sod1 Gene Expression.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colonic Neoplasms; Cytoplasm; Gene Expression Regulation, Neoplastic; Male; NF-kappa B; Plant Extracts; Rats; Rats, Sprague-Dawley; Superoxide Dismutase-1; Urochordata | 2020 |
Inhibitory Effects of Apigenin on Tumor Carcinogenesis by Altering the Gut Microbiota.
Topics: Animals; Apigenin; Azoxymethane; Carcinogenesis; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Microbiome; Mice; Mice, Inbred BALB C; RNA, Ribosomal, 16S | 2020 |
The Fragile X Mental Retardation Protein Regulates RIPK1 and Colorectal Cancer Resistance to Necroptosis.
Topics: Animals; Azoxymethane; Carcinogenesis; Case-Control Studies; Cell Culture Techniques; Cell Line, Tumor; Colon; Colorectal Neoplasms; Datasets as Topic; Disease-Free Survival; Fragile X Mental Retardation Protein; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Healthy Volunteers; Humans; Male; Mice; Mice, Knockout; Necroptosis; Neoplasm Recurrence, Local; Neoplasms, Experimental; Organoids; Prognosis; Receptor-Interacting Protein Serine-Threonine Kinases | 2021 |
Epithelial TLR4 Signaling Activates DUOX2 to Induce Microbiota-Driven Tumorigenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis-Associated Neoplasms; Colitis, Ulcerative; Colon; Datasets as Topic; Dextran Sulfate; Disease Models, Animal; Dual Oxidases; Gastrointestinal Microbiome; Germ-Free Life; Humans; Hydrogen Peroxide; Intestinal Mucosa; Membrane Proteins; Mice; Mice, Knockout; NADPH Oxidase 1; Toll-Like Receptor 4 | 2021 |
Effects of combined treatment with Indomethacin and Juglone on AOM/DSS induced colon carcinogenesis in Balb/c mice: Roles of inflammation and apoptosis.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogenesis; Cell Count; Cell Line, Tumor; Collagen; Colonic Neoplasms; Dextran Sulfate; Indomethacin; Inflammation; Male; Mast Cells; Mice, Inbred BALB C; Naphthoquinones | 2021 |
Behaviour of citrus pectin and modified citrus pectin in an azoxymethane/dextran sodium sulfate (AOM/DSS)-induced rat colorectal carcinogenesis model.
Topics: Acetates; Animals; Azoxymethane; Bifidobacterium; Blood Glucose; Body Weight; Butyrates; Carcinogenesis; Chromatography, High Pressure Liquid; Citrus; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Hydrogen-Ion Concentration; Lactic Acid; Lactobacillaceae; Male; Metagenomics; Pectins; Phylogeny; Propionates; Proteobacteria; Rats; Rats, Inbred F344; Triglycerides | 2021 |
The Glucocorticoid Receptor in Intestinal Epithelial Cells Alleviates Colitis and Associated Colorectal Cancer in Mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colitis-Associated Neoplasms; Dextran Sulfate; Female; Gene Expression Profiling; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Knockout; Permeability; Receptors, Glucocorticoid | 2021 |
Vitamin E delta-tocotrienol and metabolite 13'-carboxychromanol inhibit colitis-associated colon tumorigenesis and modulate gut microbiota in mice.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Benzopyrans; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Fatty Acids; Feces; Gastrointestinal Microbiome; Humans; Inflammation; Interleukin-1beta; Male; Mice; Mice, Inbred BALB C; RNA, Ribosomal, 16S; Vitamin E | 2021 |
Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis.
Topics: Acrolein; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred A; RNA-Binding Proteins | 2021 |
Vitexin prevents colitis-associated carcinogenesis in mice through regulating macrophage polarization.
Topics: Animals; Anticarcinogenic Agents; Apigenin; Azoxymethane; Carcinogenesis; Colitis; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Inflammatory Bowel Diseases; Macrophages; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III | 2021 |
Glycyrrhizin Attenuates Carcinogenesis by Inhibiting the Inflammatory Response in a Murine Model of Colorectal Cancer.
Topics: Animals; Azoxymethane; Carcinogenesis; Colon; Colorectal Neoplasms; Disease Models, Animal; Female; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Interleukin-6; Mice; Mice, Inbred ICR; NF-kappa B; Signal Transduction; Tumor Necrosis Factor-alpha | 2021 |
An Optimized Protocol of Azoxymethane-Dextran Sodium Sulfate Induced Colorectal Tumor Model in Mice.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Body Weight; Carcinogenesis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Male; Mice, Inbred C57BL | 2019 |
Inhibitory effects of a selective prostaglandin E2 receptor antagonist RQ-15986 on inflammation-related colon tumorigenesis in APC-mutant rats.
Topics: Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; Benzamides; Carcinogenesis; Cell Proliferation; Chemokine CCL2; Colonic Neoplasms; Dextran Sulfate; Dinoprostone; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Interleukin-18; Interleukin-6; Mutation; Rats; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Tumor Necrosis Factor-alpha | 2021 |
Transcriptome analysis of potential candidate genes and molecular pathways in colitis-associated colorectal cancer of Mkp-1-deficient mice.
Topics: Animals; Azoxymethane; Biomarkers, Tumor; Carcinogenesis; Colitis; Colitis-Associated Neoplasms; Computational Biology; Dextran Sulfate; Disease Models, Animal; Dual Specificity Phosphatase 1; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Knockout; Prognosis; Protein Interaction Mapping; Protein Interaction Maps; RNA-Seq; Signal Transduction | 2021 |
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
Topics: Animals; Apigenin; Azoxymethane; Carcinogenesis; Colitis-Associated Neoplasms; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Glucuronates; HT29 Cells; Humans; Male; Mice; Wnt Signaling Pathway | 2021 |
The immunomodulatory effects of topiramate on azoxymethane-induced colon carcinogenesis in rats: The role of the inflammatory cascade, vascular endothelial growth factor, AKT/mTOR/MAP kinase signaling and the apoptotic markers.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogenesis; Colon; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Intestinal Mucosa; Male; MAP Kinase Signaling System; Neoplasms, Experimental; Proto-Oncogene Proteins c-akt; Rats; Topiramate; TOR Serine-Threonine Kinases; Tumor Microenvironment | 2021 |
Ganoderma lucidum polysaccharide modulates gut microbiota and immune cell function to inhibit inflammation and tumorigenesis in colon.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Dysbiosis; Fungal Polysaccharides; Gastrointestinal Microbiome; Humans; Inflammation; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; RAW 264.7 Cells; Reishi; Signal Transduction | 2021 |
Sildenafil Suppresses Inflammation-Driven Colorectal Cancer in Mice.
Topics: Administration, Oral; Animals; Apoptosis; Azoxymethane; Carcinogenesis; Colitis; Colon; Colorectal Neoplasms; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dextran Sulfate; Humans; Immunohistochemistry; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Phosphodiesterase 5 Inhibitors; Polyps; Signal Transduction; Sildenafil Citrate | 2017 |
Clostridium butyricum partially regulates the development of colitis-associated cancer through miR-200c.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Clostridium butyricum; Colitis; Colonic Neoplasms; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization, Fluorescence; Inflammation; Interleukin-12; Mice; MicroRNAs; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2017 |
Sphingosine kinase 1 expression enhances colon tumor growth.
Topics: Aged; Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Enterocytes; Female; HT29 Cells; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Neoplasm Staging; Phosphotransferases (Alcohol Group Acceptor) | 2017 |
E-cadherin Mediates the Preventive Effect of Vitamin D3 in Colitis-associated Carcinogenesis.
Topics: Animals; Azoxymethane; beta Catenin; Cadherins; Carcinogenesis; Cell Proliferation; Cholecalciferol; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Up-Regulation; Vitamins | 2017 |
Role of intestinal microbiome in American ginseng-mediated colon cancer prevention in high fat diet-fed AOM/DSS mice [corrected].
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Diet, High-Fat; Gastrointestinal Microbiome; Male; Mice; Panax; Plant Extracts; Plant Roots | 2018 |
Enhancing miR-132 expression by aryl hydrocarbon receptor attenuates tumorigenesis associated with chronic colitis.
Topics: Acetylcholinesterase; Animals; Azoxymethane; Carcinogenesis; Cell Movement; Cells, Cultured; Colitis, Ulcerative; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Inflammation Mediators; Macrophages; Mice; Mice, Inbred C57BL; MicroRNAs; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; RNA, Small Interfering | 2017 |
IL-17A-Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Cells, Cultured; Clustered Regularly Interspaced Short Palindromic Repeats; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Epithelial Cells; Gene Expression Regulation, Neoplastic; Interleukin-17; Mice; Mice, Inbred C57BL; Mice, Knockout; Pregnancy Proteins; Receptors, Interleukin; Wound Healing | 2017 |
The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.
Topics: Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Cancer-Associated Fibroblasts; Carcinogenesis; Cell Proliferation; Coculture Techniques; Colorectal Neoplasms; Cytoskeletal Proteins; DNA-Binding Proteins; Fibroblasts; Humans; Intracellular Signaling Peptides and Proteins; LIM Domain Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prognosis; Protein-Lysine 6-Oxidase; Signal Transduction; Stromal Cells; Tumor Cells, Cultured | 2018 |
Methylglyoxal displays colorectal cancer-promoting properties in the murine models of azoxymethane and CT26 isografts.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Cell Line; Cholesterol, LDL; Colorectal Neoplasms; Disease Models, Animal; Humans; Inflammation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Oxidative Stress; Precancerous Conditions; Pyruvaldehyde; Transplantation, Isogeneic | 2018 |
Structural shift of gut microbiota during chemo-preventive effects of epigallocatechin gallate on colorectal carcinogenesis in mice.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Carcinogens; Catechin; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Microbiome; Humans; Mice; Rectum; RNA, Ribosomal, 16S | 2017 |
Methods for In Vivo Functional Studies of Chromatin-Modifying Enzymes in Early Steps of Colon Carcinogenesis.
Topics: Animals; Azoxymethane; Benzeneacetamides; Carcinogenesis; Chromatin; Colon; Colorectal Neoplasms; Dextran Sulfate; DNA Helicases; DNA-Binding Proteins; Histones; Humans; Intestinal Mucosa; Lysine Acetyltransferase 5; Mice; Mice, Transgenic; Neoplasms, Experimental; Pyridines; Trans-Activators; Transcription Factors; Wnt Signaling Pathway | 2018 |
Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis, Ulcerative; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Inflammation; Macrophage Activation; Macrophages; Male; Mice; Ornithine Decarboxylase; Transcription, Genetic; Up-Regulation | 2018 |
Dro1/Ccdc80 inactivation promotes AOM/DSS-induced colorectal carcinogenesis and aggravates colitis by DSS in mice.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Epithelial-Mesenchymal Transition; Extracellular Matrix Proteins; Genes, Tumor Suppressor; Glycoproteins; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout | 2018 |
HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice.
Topics: Animals; Antigens, Ly; ATP-Binding Cassette Transporters; Azoxymethane; Basic Helix-Loop-Helix Transcription Factors; Carcinogenesis; CD11b Antigen; Colitis; Colon; Dextran Sulfate; Disease Progression; Disease Susceptibility; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Knockout; Myeloid Cells; Promoter Regions, Genetic; Tumor Necrosis Factor-alpha; Von Hippel-Lindau Tumor Suppressor Protein | 2018 |
The Rac1 splice form Rac1b favors mouse colonic mucosa regeneration and contributes to intestinal cancer progression.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Progression; Epithelial Cells; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Neuropeptides; rac1 GTP-Binding Protein; Signal Transduction | 2018 |
Cannabinoid Receptor-1 Up-regulation in Azoxymethane (AOM)-treated Mice After Dietary Treatment with Quercetin.
Topics: Animals; Apoptosis; Azoxymethane; bcl-2-Associated X Protein; Carcinogenesis; Cell Proliferation; Colonic Neoplasms; Diet; Dietary Supplements; Flavonoids; Gene Expression; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-bcl-2; Quercetin; Receptor, Cannabinoid, CB1; Up-Regulation | 2018 |
Fermented Ganjangs (Soy Sauce and Sesame Sauce) Attenuates Colonic Carcinogenesis in Azoxymethane/Dextran Sodium Sulfate-Treated C57BL/6J Mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Colon; Colonic Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Fermentation; Humans; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Sesamum; Soy Foods; Tumor Necrosis Factor-alpha | 2018 |
Early increase in blood supply (EIBS) is associated with tumor risk in the Azoxymethane model of colon cancer.
Topics: Animals; Azoxymethane; Blood Vessels; Carcinogenesis; Colon; Colonic Neoplasms; Dextrans; Disease Models, Animal; Fluorescein-5-isothiocyanate; Hemoglobins; Humans; Mice; Microscopy, Confocal; Renin-Angiotensin System | 2018 |
DNA damage response genes mark the early transition from colitis to neoplasia in colitis-associated colon cancer.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Disease Progression; DNA Damage; Gene Expression Regulation; Inflammation; Inflammatory Bowel Diseases; Intestines; Male; Mice; Mice, Inbred C57BL; Microsatellite Instability; Signal Transduction | 2018 |
TRIM27 mediates STAT3 activation at retromer-positive structures to promote colitis and colitis-associated carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Cell Transformation, Neoplastic; Colitis; Dextran Sulfate; DNA-Binding Proteins; HEK293 Cells; HeLa Cells; HT29 Cells; Humans; Interleukin-6; Mice; Nuclear Proteins; Signal Transduction; STAT3 Transcription Factor; Ubiquitin-Protein Ligases | 2018 |
Protective Effect of Chickpea Protein Hydrolysates on Colon Carcinogenesis Associated With a Hypercaloric Diet.
Topics: Animals; Azoxymethane; Carcinogenesis; Cicer; Colon; Colonic Neoplasms; Diet; Disease Models, Animal; Energy Intake; Male; Mice; Protective Agents; Protein Hydrolysates; Seeds | 2019 |
The phosphatidic acid phosphatase lipin-1 facilitates inflammation-driven colon carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Chemokine CXCL1; Chemokine CXCL2; Colitis; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Humans; Inflammation; Inflammatory Bowel Diseases; Interleukin-23; Macrophages; Mice; Mice, Inbred BALB C; Mucous Membrane; Nuclear Proteins; Phosphatidate Phosphatase | 2018 |
Dietary Supplementation of Selenoneine-Containing Tuna Dark Muscle Extract Effectively Reduces Pathology of Experimental Colorectal Cancers in Mice.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Colitis; Colorectal Neoplasms; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Histidine; Mice; Muscles; Organoselenium Compounds; Spleen; Tuna | 2018 |
A mixture of Persistent Organic Pollutants (POPs) and Azoxymethane (AOM) show potential synergistic effects on intestinal tumorigenesis in the A/J Min/+ mouse model.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colonic Neoplasms; Diet; Disease Models, Animal; Drug Synergism; Environmental Pollutants; Female; Intestines; Liver; Male; Mice; Mice, Inbred A; Organic Chemicals | 2019 |
Effects of Grape Juice in Superoxide Dismutase and Catalase in Colorectal Cancer Carcinogenesis Induced by Azoxymethane
Topics: Animals; Antioxidants; Azoxymethane; Carcinogenesis; Carcinogens; Catalase; Colorectal Neoplasms; Fruit and Vegetable Juices; Intestinal Mucosa; Male; Oxidants; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Vitis | 2018 |
Folate/Vitamin B12 Supplementation Combats Oxidative Stress-Associated Carcinogenesis in a Rat Model of Colon Cancer.
Topics: Animals; Azoxymethane; Carcinogenesis; Colonic Neoplasms; Dietary Supplements; Disease Models, Animal; Folic Acid; Glutathione; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Vitamin B 12 | 2019 |
Intermittent hypoxia promotes carcinogenesis in azoxymethane and dextran sodium sulfate-induced colon cancer model.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Hypoxia; Inflammation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress | 2019 |
Glucocorticoids promote the development of azoxymethane and dextran sulfate sodium-induced colorectal carcinoma in mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Drug Synergism; Glucocorticoids; Humans; Immunohistochemistry; Ki-67 Antigen; Male; Mice, Inbred C57BL; Proliferating Cell Nuclear Antigen; Transcription Factor RelA | 2019 |
Silibinin Retards Colitis-associated Carcinogenesis by Repression of Cdc25C in Mouse Model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Azoxymethane; Carcinogenesis; Carcinogens; cdc25 Phosphatases; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Inbred C57BL; Silybin | 2019 |
A novel mouse model of sporadic colon cancer induced by combination of conditional Apc genes and chemical carcinogen in the absence of Cre recombinase.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colonic Neoplasms; Disease Models, Animal; Genes, APC; Integrases; Mice; Mice, Inbred C57BL | 2019 |
Cancer testis antigen 55 deficiency attenuates colitis-associated colorectal cancer by inhibiting NF-κB signaling.
Topics: Animals; Antigens, Neoplasm; Azoxymethane; Carcinogenesis; Cell Proliferation; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; HCT116 Cells; HEK293 Cells; Humans; I-kappa B Kinase; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; NF-kappa B; Phosphorylation; Signal Transduction; Tumor Necrosis Factor-alpha | 2019 |
Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy.
Topics: Animals; Azoxymethane; Carcinogenesis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Integrases; Intestine, Small; Mice; Mice, Knockout; Neoplastic Stem Cells; Octamer Transcription Factor-1; Organoids; Receptors, G-Protein-Coupled; Regeneration; Signal Transduction; Survival Analysis; Tamoxifen | 2019 |
Platelet Depletion/Transfusion as a Lethal Factor in a Colitis-associated Cancer Mouse Model.
Topics: Animals; Azoxymethane; Blood Platelets; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Mice; Mice, Knockout; Platelet Transfusion; Toll-Like Receptor 4 | 2019 |
Oestrogens promote tumorigenesis in a mouse model for colitis-associated cancer.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Estradiol; Estrogens; Female; Hormone Replacement Therapy; Immunohistochemistry; Medroxyprogesterone; Mice; Ovariectomy | 2014 |
Diet induced obesity increases the risk of colonic tumorigenesis in mice.
Topics: Aberrant Crypt Foci; Analysis of Variance; Animals; Azoxymethane; Body Weight; Carcinogenesis; Carcinogens; Colonic Neoplasms; Energy Intake; Male; Mice; Mice, Inbred C57BL; Obesity; Random Allocation; Weight Gain | 2013 |
Ay allele promotes azoxymethane-induced colorectal carcinogenesis by macrophage migration in hyperlipidemic/diabetic KK mice.
Topics: Alleles; Animals; Azoxymethane; beta Catenin; Carcinogenesis; Cell Movement; Cocarcinogenesis; Colorectal Neoplasms; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Hyperlipidemias; Inflammation; Insulin; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Inbred NOD; RNA, Messenger; Triglycerides | 2013 |
Prevention of familial adenomatous polyp development in APC min mice and azoxymethane-induced colon carcinogenesis in F344 Rats by ω-3 fatty acid rich perilla oil.
Topics: Aberrant Crypt Foci; Adenomatous Polyposis Coli; alpha-Linolenic Acid; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Colonic Neoplasms; Corn Oil; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Female; Intestinal Mucosa; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Plant Oils; Rats; Rats, Inbred F344 | 2013 |
Utility of a bacterial infection model to study epithelial-mesenchymal transition, mesenchymal-epithelial transition or tumorigenesis.
Topics: Animals; Azoxymethane; Bacterial Infections; Carcinogenesis; Cell Differentiation; Colon; Disease Models, Animal; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Mice; Mice, Nude; Receptors, Notch; Signal Transduction; Stem Cells; Wnt Proteins | 2014 |
Methanolic extract of white asparagus shoots activates TRAIL apoptotic death pathway in human cancer cells and inhibits colon carcinogenesis in a preclinical model.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Asparagus Plant; Azoxymethane; Carcinogenesis; Caspase 3; Caspase 8; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Enzyme Activation; Humans; Intestinal Mucosa; Male; Methanol; Plant Extracts; Plant Shoots; Rats; Rats, Wistar; TNF-Related Apoptosis-Inducing Ligand | 2013 |
Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Azoxymethane; Carcinogenesis; Colitis; Colonic Neoplasms; Deoxyguanosine; Dextran Sulfate; Diet; DNA Damage; Epidermal Growth Factor; Gene Expression Regulation; Inflammation; Mice; Mice, Inbred C57BL; Selenium; Signal Transduction; Transforming Growth Factor beta; Weight Loss | 2013 |
Deletion of glutathione peroxidase-2 inhibits azoxymethane-induced colon cancer development.
Topics: Adenoma; Animals; Antioxidants; Apoptosis; Azoxymethane; beta Catenin; Carcinogenesis; Colonic Neoplasms; Diet; Dietary Supplements; Epithelial Cells; Gene Deletion; Glutathione Peroxidase; Humans; Intestinal Mucosa; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Selenium | 2013 |
Nano-architectural alterations in mucus layer fecal colonocytes in field carcinogenesis: potential for screening.
Topics: Adenoma; Animals; Azoxymethane; Carcinogenesis; Colon; Colonoscopy; Colorectal Neoplasms; Disease Models, Animal; Early Detection of Cancer; Endoscopy; Feces; Intestinal Mucosa; Male; Mass Screening; Microscopy; Occult Blood; Optics and Photonics; Rats; Rats, Inbred F344 | 2013 |
CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis.
Topics: Adoptive Transfer; Animals; Azoxymethane; Carcinogenesis; CD8-Positive T-Lymphocytes; Cells, Cultured; Chemokine CXCL1; Chemotaxis; Colitis; Colorectal Neoplasms; Cytotoxicity, Immunologic; Dextran Sulfate; Dinoprostone; Humans; Inflammation Mediators; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Mice, Knockout; Myeloid Cells; Receptors, Interleukin-8B; Tumor Microenvironment | 2013 |
Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol.
Topics: Animals; Azoxymethane; Cannabidiol; Cannabinoid Receptor Antagonists; Cannabis; Carcinogenesis; Carcinoma; Cell Proliferation; Cell Survival; CHO Cells; Colonic Neoplasms; Cricetinae; Cricetulus; Epithelial Cells; HCT116 Cells; Humans; Male; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Random Allocation; Receptors, Cannabinoid; Xenograft Model Antitumor Assays | 2014 |
Characterization of hERG1 channel role in mouse colorectal carcinogenesis.
Topics: Adenomatous Polyposis Coli; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colorectal Neoplasms; Disease Models, Animal; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Intestine, Large; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Proteins; Neovascularization, Pathologic; Piperidines; Proto-Oncogene Proteins c-akt; Pyridines; Vascular Endothelial Growth Factor A | 2013 |
Identification of a microRNA landscape targeting the PI3K/Akt signaling pathway in inflammation-induced colorectal carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2014 |
CD24 knockout prevents colorectal cancer in chemically induced colon carcinogenesis and in APC(Min)/CD24 double knockout transgenic mice.
Topics: Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; beta Catenin; Carcinogenesis; CD24 Antigen; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Dinoprostone; Disease Progression; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Promoter Regions, Genetic; Signal Transduction; Tumor Burden | 2014 |
Azoxymethane-induced colon carcinogenesis in mice occurs independently of de novo thymidylate synthesis capacity.
Topics: Animals; Azoxymethane; Carcinogenesis; Choline Deficiency; Colon; Colonic Neoplasms; Crosses, Genetic; Disease Models, Animal; DNA; Extracellular Matrix Proteins; Folic Acid; Folic Acid Deficiency; Glycine Hydroxymethyltransferase; Male; Mice; Mice, Knockout; Mice, Transgenic; Neoplasm Proteins; Protein-Lysine 6-Oxidase; Random Allocation; Thymidine Monophosphate; Tumor Burden; Uracil | 2014 |
Amelioration of azoxymethane induced-carcinogenesis by reducing oxidative stress in rat colon by natural extracts.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Azoxymethane; Carcinogenesis; Carica; Colon; Colonic Neoplasms; Dietary Supplements; Fruit; Glutathione; Humans; Intestinal Mucosa; Lipid Peroxidation; Lythraceae; Male; Micronuclei, Chromosome-Defective; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Seaweed | 2014 |
Canola oil influence on azoxymethane-induced colon carcinogenesis, hypertriglyceridemia and hyperglycemia in Kunming mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colonic Neoplasms; Fatty Acids, Monounsaturated; Female; Hyperglycemia; Hypertriglyceridemia; Male; Mice; Organ Size; Precancerous Conditions; Rapeseed Oil | 2014 |
Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Azoxymethane; Berberine; Carcinogenesis; Caspase 3; Cell Line, Tumor; Colon; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 2; eIF-2 Kinase; Female; HCT116 Cells; Humans; Mice; NF-kappa B; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2015 |
A non-digestible fraction of the common bean (Phaseolus vulgaris L.) induces cell cycle arrest and apoptosis during early carcinogenesis.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Carcinogenesis; Cell Cycle Checkpoints; Cell Line, Tumor; Colon; Colonic Neoplasms; Cooking; Dietary Carbohydrates; Dietary Fiber; Dietary Proteins; Digestion; Flavonoids; Male; Phaseolus; Plant Extracts; Rats; Rats, Sprague-Dawley | 2014 |
Combinational chemoprevention effect of celecoxib and an oral antiangiogenic LHD4 on colorectal carcinogenesis in mice.
Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Celecoxib; Colon; Colonic Polyps; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Deoxycholic Acid; Dextran Sulfate; Drug Therapy, Combination; Heparin, Low-Molecular-Weight; Inflammation; Male; Mice, Inbred ICR; Neovascularization, Pathologic; Pyrazoles; Sulfonamides; Tumor Burden | 2014 |
Kimchi protects against azoxymethane/dextran sulfate sodium-induced colorectal carcinogenesis in mice.
Topics: Animals; Azoxymethane; Brassica; Carcinogenesis; Colon; Colonic Neoplasms; Dextran Sulfate; Humans; Interferon-gamma; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Tumor Necrosis Factor-alpha | 2014 |
Bovine milk-derived α-lactalbumin inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sodium sulfate-treated mice.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Carcinogenesis; Cattle; Colon; Colonic Neoplasms; Dextran Sulfate; Dietary Supplements; Dinoprostone; Inflammation; Interleukin-1beta; Lactalbumin; Male; Mice; Mice, Inbred C57BL; Milk; Occult Blood; Organ Size; Tumor Necrosis Factor-alpha | 2014 |
Brewers' rice induces apoptosis in azoxymethane-induced colon carcinogenesis in rats via suppression of cell proliferation and the Wnt signaling pathway.
Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Carcinogenesis; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Male; Oryza; Rats; Rats, Sprague-Dawley; Wnt Signaling Pathway | 2014 |
In vivo molecular mapping of the tumor microenvironment in an azoxymethane-treated mouse model of colon carcinogenesis.
Topics: Animals; Azoxymethane; Biomarkers, Tumor; Carcinogenesis; Carcinogens; Colonic Neoplasms; Colonoscopes; Colonoscopy; Disease Progression; Female; Mice; Time Factors; Tomography, Optical Coherence; Tumor Microenvironment | 2015 |
Diverse roles of STING-dependent signaling on the development of cancer.
Topics: Animals; Azoxymethane; Carcinogenesis; Colonic Neoplasms; Humans; Immunity, Innate; Membrane Proteins; Mice; Mice, Knockout; Signal Transduction; Transcriptional Activation | 2015 |
Protective Effects of Turbinaria ornata and Padina pavonia against Azoxymethane-Induced Colon Carcinogenesis through Modulation of PPAR Gamma, NF-κB and Oxidative Stress.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Colonic Neoplasms; Glutathione; Glutathione Peroxidase; Humans; Inflammation; Lipid Peroxidation; Male; Malondialdehyde; Mice; NF-kappa B; Nitric Oxide; Oxidative Stress; Phaeophyceae; PPAR gamma; Seaweed; Superoxide Dismutase; Tumor Suppressor Protein p53 | 2015 |
Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde.
Topics: Acrolein; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Chemoprevention; Cinnamomum zeylanicum; Colonic Neoplasms; Cytoprotection; Dextran Sulfate; Diet; HCT116 Cells; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2 | 2015 |
PAF receptor antagonist Ginkgolide B inhibits tumourigenesis and angiogenesis in colitis-associated cancer.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Dextran Sulfate; Female; Ginkgolides; Lactones; Mice; Neovascularization, Pathologic; Plant Extracts; Platelet Activating Factor | 2015 |
Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis.
Topics: Adenocarcinoma; Animals; Azoxymethane; Bacteroides fragilis; Blotting, Western; Carcinogenesis; Carcinogens; Cell Line, Tumor; Cell Proliferation; Chemokine CCL20; Colitis; Colonic Neoplasms; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Enterobacteriaceae; Exosomes; Immunohistochemistry; In Situ Hybridization, Fluorescence; Inflammation; Intestinal Mucosa; Lysophospholipids; Mice; Myeloid Differentiation Factor 88; Nanoparticles; Neoplasm Transplantation; Reverse Transcriptase Polymerase Chain Reaction; Sphingosine; Th17 Cells | 2015 |
Smad2/3 linker phosphorylation is a possible marker of cancer stem cells and correlates with carcinogenesis in a mouse model of colitis-associated colorectal cancer.
Topics: Animals; Azoxymethane; beta Catenin; Biomarkers, Tumor; Carcinogenesis; Colitis; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Ki-67 Antigen; Male; Mice; Neoplastic Stem Cells; Phosphorylation; Proto-Oncogene Proteins c-myc; Serine; Signal Transduction; Smad2 Protein; Smad3 Protein; SOX9 Transcription Factor | 2015 |
HIC1 Tumor Suppressor Loss Potentiates TLR2/NF-κB Signaling and Promotes Tissue Damage-Associated Tumorigenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Epithelial Cells; Gene Knockdown Techniques; Humans; Intestines; Kruppel-Like Transcription Factors; Mice; Mice, Transgenic; NF-kappa B; Signal Transduction; Toll-Like Receptor 2; Tumor Suppressor Proteins; Up-Regulation | 2015 |
St. John's Wort Attenuates Colorectal Carcinogenesis in Mice through Suppression of Inflammatory Signaling.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; Diet; Dietary Supplements; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Hypericum; Inflammation; Male; Mice; NF-kappa B; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Plant Extracts; Signal Transduction | 2015 |
Curcumin ameliorates the tumor-enhancing effects of a high-protein diet in an azoxymethane-induced mouse model of colon carcinogenesis.
Topics: Ammonia; Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Colon; Colonic Neoplasms; Curcumin; Cyclooxygenase 2; Diet; Dietary Proteins; Fatty Acids; Feces; Female; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase Type II; Tumor Necrosis Factor-alpha | 2015 |
Ghrelin administration suppresses inflammation-associated colorectal carcinogenesis in mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Ghrelin; Inflammation; Male; Mice; Mice, Inbred C57BL | 2015 |
Targeting phospholipase D1 attenuates intestinal tumorigenesis by controlling β-catenin signaling in cancer-initiating cells.
Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Blotting, Western; Carcinogenesis; Dextran Sulfate; DNA Primers; Flow Cytometry; HEK293 Cells; Humans; Immunohistochemistry; Immunoprecipitation; In Situ Nick-End Labeling; Intestinal Neoplasms; Mice; MicroRNAs; Mutagenesis, Site-Directed; Phospholipase D; Real-Time Polymerase Chain Reaction; Signal Transduction; Tissue Array Analysis | 2015 |
Chemoprevention of Colonic Aberrant Crypt Foci by Novel Schiff Based Dichlorido(4-Methoxy-2-{[2-(Piperazin-4-Ium-1-Yl)Ethyl]Iminomethyl}Phenolate)Cd Complex in Azoxymethane-Induced Colorectal Cancer in Rats.
Topics: Aberrant Crypt Foci; Animals; Antineoplastic Agents; Azoxymethane; Carcinogenesis; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Male; Rats; Rats, Sprague-Dawley; Schiff Bases; Treatment Outcome | 2015 |
Chemoprevention of Azoxymethane-induced Colonic Carcinogenesis in Balb/c mice Using a Modified Pectin Alginate Probiotic.
Topics: Alginates; Animals; Azoxymethane; Carcinogenesis; Chemoprevention; Colon; Colonic Neoplasms; Disease Models, Animal; Galectins; Glucuronic Acid; Hexuronic Acids; Immunohistochemistry; Male; Mice, Inbred BALB C; Pectins; Probiotics; Vascular Endothelial Growth Factor A | 2015 |
Brewers' rice modulates oxidative stress in azoxymethane-mediated colon carcinogenesis in rats.
Topics: Animals; Antioxidants; Azoxymethane; beta Catenin; Carcinogenesis; Colon; Colonic Neoplasms; Dietary Supplements; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heme Oxygenase (Decyclizing); Male; Malondialdehyde; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oryza; Oxidative Stress; Plant Preparations; Rats, Sprague-Dawley; Superoxide Dismutase; Transcription, Genetic; Transcriptional Activation; Wnt Signaling Pathway | 2015 |
PAK1 promotes intestinal tumor initiation.
Topics: Animals; Azoxymethane; beta Catenin; Carcinogenesis; Colonoscopy; Dextrans; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Genotype; Heterozygote; Immunohistochemistry; Inflammation; Intestinal Neoplasms; Male; Mesalamine; Mice; Mice, Inbred C57BL; Mice, Knockout; p21-Activated Kinases; Signal Transduction | 2015 |
Anthocyanin-containing purple-fleshed potatoes suppress colon tumorigenesis via elimination of colon cancer stem cells.
Topics: Animals; Anthocyanins; Antineoplastic Agents; Apoptosis; Azoxymethane; bcl-2-Associated X Protein; beta Catenin; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Colonic Neoplasms; Cytochromes c; Food; Humans; In Situ Nick-End Labeling; Lentivirus; Male; Mice; Mitochondria; Neoplastic Stem Cells; RNA, Small Interfering; Solanum tuberosum; Sulindac; Tumor Suppressor Protein p53; Wnt Proteins | 2015 |
Effects of Two Traditional Chinese Cooking Oils, Canola and Pork, on pH and Cholic Acid Content of Faeces and Colon Tumorigenesis in Kunming Mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Cholic Acid; Colon; Colonic Neoplasms; Dietary Fats, Unsaturated; Fatty Acids, Monounsaturated; Feces; Female; Hydrogen-Ion Concentration; Male; Mice; Oils; Organ Size; Rapeseed Oil; Swine | 2015 |
Thrombospondin-1 in a Murine Model of Colorectal Carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Proliferation; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Immunohistochemistry; Inflammation; Mice, Inbred C57BL; Microvessels; Reproducibility of Results; RNA, Messenger; Thrombospondin 1; Up-Regulation | 2015 |
Dead Nano-Sized Lactobacillus plantarum Inhibits Azoxymethane/Dextran Sulfate Sodium-Induced Colon Cancer in Balb/c Mice.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogenesis; Cell Cycle Checkpoints; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Immunoglobulin A; Inflammation; Lactobacillus plantarum; Mice, Inbred BALB C; Particle Size | 2015 |
Genetic-deletion of Cyclooxygenase-2 Downstream Prostacyclin Synthase Suppresses Inflammatory Reactions but Facilitates Carcinogenesis, unlike Deletion of Microsomal Prostaglandin E Synthase-1.
Topics: Acetic Acid; Animals; Azoxymethane; Carcinogenesis; Colonic Neoplasms; Colonic Polyps; Cyclooxygenase 2; Cytochrome P-450 Enzyme System; Dinoprostone; Epoprostenol; Intramolecular Oxidoreductases; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Nociception; Pain; Peritonitis; Prostaglandin-E Synthases; Thioglycolates | 2015 |
Dietary Ziziphus jujuba Fruit Influence on Aberrant Crypt Formation and Blood Cells in Colitis-Associated Colorectal Cancer in Mice.
Topics: Aberrant Crypt Foci; Adenocarcinoma; Animals; Azoxymethane; Carcinogenesis; Chemoprevention; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Diet; Dietary Supplements; Disease Progression; Hyperplasia; Leukocyte Count; Leukocytes; Male; Mice; Mice, Inbred C57BL; Plant Preparations; Ziziphus | 2015 |
The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals.
Topics: Adenomatous Polyposis Coli Protein; Animals; Antibodies, Monoclonal, Humanized; Azoxymethane; Biomarkers, Tumor; Carcinogenesis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Interleukin-6; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Fluorescence; Mitochondrial Proteins; Mitogen-Activated Protein Kinases; NF-kappa B; Real-Time Polymerase Chain Reaction; Signal Transduction; STAT3 Transcription Factor | 2016 |
[Changes of macrophages in colitis-associated colonic carcinogenesis].
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Granulocyte Colony-Stimulating Factor; Macrophages; Mice; Mice, Inbred C57BL; Phenotype; Real-Time Polymerase Chain Reaction | 2016 |
Effect of Dietary Fibers on Cecal Microbiota and Intestinal Tumorigenesis in Azoxymethane Treated A/J Min/+ Mice.
Topics: Analysis of Variance; Animals; Azoxymethane; Bacteroidetes; Body Weight; Carcinogenesis; Cecum; Cellulose; Colon; Colonic Neoplasms; Diet; Dietary Fiber; Firmicutes; High-Throughput Nucleotide Sequencing; Inulin; Male; Mice; Mice, Inbred C57BL; Microbiota; RNA, Ribosomal, 16S | 2016 |
Effects of Walnut Consumption on Colon Carcinogenesis and Microbial Community Structure.
Topics: Animals; Azoxymethane; Bacteria; Carcinogenesis; Carcinogens; Colonic Neoplasms; Colonoscopy; Diet; DNA, Bacterial; Feces; Female; Gastrointestinal Microbiome; Immunohistochemistry; Male; Mice; Mice, Inbred A; Nuts; Sex Factors; Statistics, Nonparametric | 2016 |
American Ginseng Attenuates Colitis-Associated Colon Carcinogenesis in Mice: Impact on Gut Microbiota and Metabolomics.
Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Colonic Neoplasms; Dextran Sulfate; Gastrointestinal Microbiome; Male; Metabolomics; Mice; Panax | 2016 |
Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth.
Topics: Adenocarcinoma; Animals; Azoxymethane; Bone Morphogenetic Proteins; Carcinogenesis; Cell Proliferation; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Integrases; Mice, Inbred C57BL; Recombination, Genetic; Signal Transduction; Stromal Cells; Transcription, Genetic; Tumor Burden | 2016 |
The tumour suppressor CYLD regulates the p53 DNA damage response.
Topics: Animals; Apoptosis; Azoxymethane; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carcinogenesis; Cysteine Endopeptidases; Deubiquitinating Enzyme CYLD; DNA Damage; DNA Repair; Female; Genetic Predisposition to Disease; Intestinal Neoplasms; Lysine; Male; Mice; Mice, Transgenic; Signal Transduction; Skin Neoplasms; Tumor Suppressor Protein p53; Ubiquitination | 2016 |
TNIK inhibition abrogates colorectal cancer stemness.
Topics: Adenomatous Polyposis Coli Protein; Administration, Oral; Aged; Animals; Azoxymethane; beta Catenin; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; Crystallography, X-Ray; Female; Germinal Center Kinases; Humans; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Middle Aged; Mutation; Neoplastic Stem Cells; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Quinazolines; Recombinant Proteins; Ubiquitin-Protein Ligases; Wnt Proteins; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2016 |
Flavonoids Extracted from Licorice Prevents Colitis-Associated Carcinogenesis in AOM/DSS Mouse Model.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogenesis; Cell Proliferation; Colitis; Dextran Sulfate; Disease Models, Animal; Female; Flavonoids; Glycyrrhiza; Inflammatory Bowel Diseases; Interleukin-6; Janus Kinase 2; Mice; Mice, Inbred C57BL; NF-kappa B; Signal Transduction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2016 |
The role of Ly49E receptor expression on murine intraepithelial lymphocytes in intestinal cancer development and progression.
Topics: Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; Carcinogenesis; Carcinoma in Situ; Disease Models, Animal; Epithelium; Gene Expression Regulation, Neoplastic; Immunity, Cellular; Intestinal Neoplasms; Lymphocytes; Mice; Mice, Inbred Strains; Mice, Knockout; NK Cell Lectin-Like Receptor Subfamily A; Tumor Burden; Urokinase-Type Plasminogen Activator | 2016 |
Weight loss following diet-induced obesity does not alter colon tumorigenesis in the AOM mouse model.
Topics: Animals; Azoxymethane; Body Weight; Carcinogenesis; Cell Proliferation; Colon; Colonic Neoplasms; Diet, High-Fat; Disease Models, Animal; Liver; Liver Neoplasms; Macrophages; Mice; Obesity; T-Lymphocytes; Weight Loss | 2016 |
The p53 status can influence the role of Sam68 in tumorigenesis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Azoxymethane; Carcinogenesis; Haploinsufficiency; Mice; Mice, Inbred C57BL; RNA-Binding Proteins; Tumor Suppressor Protein p53 | 2016 |
Prevention of azoxymethane/dextran sodium sulfate-induced mouse colon carcinogenesis by processed Aloe vera gel.
Topics: Adenocarcinoma; Aloe; Animals; Azoxymethane; Carcinogenesis; CDX2 Transcription Factor; Cell Cycle; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gels; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; NF-kappa B; Plant Extracts; Tumor Suppressor Proteins | 2016 |
Repression of MicroRNA Function Mediates Inflammation-associated Colon Tumorigenesis.
Topics: Animals; Azoxymethane; Caco-2 Cells; Carcinogenesis; Carcinoma; Cell Line, Tumor; Colitis; Colon; Colonic Neoplasms; Cytidine Deaminase; Cytokines; DEAD-box RNA Helicases; Dextran Sulfate; Fibroblasts; Flow Cytometry; HCT116 Cells; HT29 Cells; Humans; Immunoblotting; Immunohistochemistry; Inflammation; Interleukin-1alpha; Interleukin-1beta; Mice; MicroRNAs; Ribonuclease III; Tumor Necrosis Factor-alpha | 2017 |
Rapidly cycling Lgr5
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; beta Catenin; Carcinogenesis; Carcinogens; Cell Cycle; Cell Differentiation; Cell Nucleus; Chemoprevention; Colon; Colonic Neoplasms; Curcumin; Diet; DNA Breaks, Double-Stranded; DNA Modification Methylases; DNA Repair Enzymes; Fatty Acids, Omega-3; Fish Oils; Green Fluorescent Proteins; Mice; Receptors, G-Protein-Coupled; Regeneration; Risk Factors; Signal Transduction; Stem Cells; Subcellular Fractions; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2016 |
Activins and their related proteins in colon carcinogenesis: insights from early and advanced azoxymethane rat models of colon cancer.
Topics: Activins; Adenocarcinoma; Animals; Azoxymethane; Biomarkers, Tumor; Carcinogenesis; Colonic Neoplasms; Disease Progression; Follistatin; Gene Expression; Male; Precancerous Conditions; Rats, Wistar | 2016 |
Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor-κB, and Up-regulating Expression of MicroRNA-21.
Topics: Adenomatous Polyposis Coli Protein; Aged; Animals; Azoxymethane; Carcinogenesis; Cell Movement; Cell Proliferation; Colitis; Colonic Neoplasms; Dextran Sulfate; DNA, Bacterial; Down-Regulation; Female; Fusobacterium Infections; Fusobacterium nucleatum; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; MicroRNAs; Myeloid Differentiation Factor 88; NF-kappa B; p120 GTPase Activating Protein; Prognosis; RNA, Small Interfering; Signal Transduction; Toll-Like Receptor 4; Up-Regulation | 2017 |
Açaí Berries Inhibit Colon Tumorigenesis in Azoxymethane/Dextran Sulfate Sodium-Treated Mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Carcinogens; Colon; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Down-Regulation; Euterpe; Genes, bcl-2; Male; Mice; Peroxidase; Phytotherapy; Powders; Proliferating Cell Nuclear Antigen | 2017 |
Daily Intake of High-Fat Diet with Lysophosphatidic Acid-Rich Soybean Phospholipids Augments Colon Tumorigenesis in Kyoto Apc Delta Rats.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Complex Mixtures; Dextran Sulfate; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Food-Drug Interactions; Glycine max; Intestinal Mucosa; Lysophospholipids; Rats; Statistics as Topic | 2017 |
Synergistic chemopreventive effects of nobiletin and atorvastatin on colon carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Atorvastatin; Azoxymethane; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chemoprevention; Colon; Colonic Neoplasms; Drug Synergism; Drug Therapy, Combination; Flavones; HT29 Cells; Humans; Male; Mice; Rats; Rats, Inbred F344 | 2017 |
Prevention of tumorigenesis in mice by exercise is dependent on strain background and timing relative to carcinogen exposure.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Genetic Background; Intestinal Neoplasms; Mice; Physical Conditioning, Animal | 2017 |