azoxymethane has been researched along with Adenoma in 118 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (7.63) | 18.7374 |
| 1990's | 35 (29.66) | 18.2507 |
| 2000's | 40 (33.90) | 29.6817 |
| 2010's | 31 (26.27) | 24.3611 |
| 2020's | 3 (2.54) | 2.80 |
| Authors | Studies |
|---|---|
| Adileh, M; Baslan, T; Brown, AM; Fuks, Z; Hsu, KS; Hua, G; Klingler, S; Kolesnick, R; Martin, ML; Paty, PB; Zhang, Z | 1 |
| Ajayi, BO; Ajeigbe, OF; Anyebe, DA; Farombi, EO; Maruf, OR; Opafunso, IT | 1 |
| Biddick, L; Janakiram, NB; Li, Q; Lightfoot, S; Lubet, RA; Madka, V; Miller, MS; Mohammed, A; Rao, CV; Sei, S; Singh, A; Steele, VE; Suen, CS; Zhang, Y | 1 |
| He, JM; Hu, JN; Liang, X | 1 |
| Ganta, V; Janakiram, NB; Kumar, G; Lightfoot, S; Lubet, R; Madka, V; Mohammed, A; Panneerselvam, J; Pathuri, G; Rao, CV; Steele, VE; Suen, CS; Zhang, Y | 1 |
| Agle, KA; Chen, X; Drobyski, WR; Huang, YW; Oshima, K; Pan, P; Wang, LS; Yearsley, MM; Yu, J; Zhang, J | 1 |
| Andreatos, N; Angelou, A; Antoniou, E; Damaskos, C; Garmpis, N; Margonis, GA; Papalois, A; Theocharis, S; Theodoropoulos, G; Xiao, W; Yuan, C; Zacharioudaki, A; Zografos, G | 1 |
| Bravou, V; Champeris Tsaniras, S; Giannou, AD; Gorgoulis, VG; Karousi, F; Lalioti, ME; Lygerou, Z; Nikou, S; Pateras, IS; Patmanidi, AL; Petropoulos, M; Stathopoulos, GT; Taraviras, S; Tserou, P; Villiou, M | 1 |
| Chang, YY; Huang, WJ; Jeng, YM; Jhuang, YL; Yang, CY; Yu, IS; Yu, LC | 1 |
| Bissonnette, M; Chen, CT; Chen, NT; Dougherty, U; Hart, J; Lo, LW; Souris, JS; Waller, JV; Zhang, HJ | 1 |
| Backman, V; Kunte, D; Mutyal, NN; Radosevich, A; Roy, HK; Stypula, Y; Tiwari, AK; Wali, R | 1 |
| Al-Rabadi, L; Bugni, JM; Karagiannides, I; Pothoulakis, C; Stavrakis, D; Tuominen, I | 1 |
| Esa, NM; Ithnin, H; Saad, N | 1 |
| Brigelius-Flohé, R; Chu, FF; Esworthy, RS; Florian, S; Kipp, AP; Müller, MF; Osterhoff, M; Pommer, S | 1 |
| Backman, V; Crawford, SE; Damania, DP; DelaCruz, M; Kunte, DP; Roy, HK; Subramanian, H; Tiwari, AK; Wali, RK | 1 |
| Gao, Y; Guo, QL; Guo, XK; Hu, R; Jia, JM; Jiang, JW; Jiang, ZY; Sun, HP; Sun, ZY; Tao, L; Wang, YJ; Xi, MY; Xu, LL; Xu, XL; Xue, X; Yang, X; Ye, M; You, QD; Zhang, MY; Zhang, XJ; Zhu, JF | 1 |
| Brewer, M; Bryant, T; Janakiram, NB; Lightfoot, S; Mohammed, A; Rao, CV; Steele, VE; Zhang, Y | 1 |
| Hosono, A; Seki, T; Takai, S; Yamaguchi, M | 1 |
| Dubois, RN | 1 |
| Amos-Landgraf, JM; Clipson, L; Dove, WF; Dunkin, E; Ederveen, AG; Groothuis, PG; Heijmans, J; Hommes, DW; Krentz, KJ; Mosselman, S; Muncan, V; Shedlovsky, A; van den Brink, GR; Wielenga, MC | 1 |
| Barton, JK; Keenan, MR; Leung, SJ; Rice, PS; Wall, RA | 1 |
| Burkitt, MD; Caamano, JH; Dimaline, R; Duckworth, CA; Gerondakis, S; Hanedi, AF; O'Reilly, LA; Pritchard, DM; Putoczki, TL; Tang, JM; Williams, JM | 1 |
| Chen, T; Clinton, SK; Liu, Z; Pan, Z; Riedl, KM; Schwartz, SJ; Shi, N; Wang, Y; Zhang, X | 1 |
| Biffoni, M; Bignami, M; Boirivant, M; De Luca, G; Di Carlo, E; Di Meo, S; Grasso, F; Pasquini, L; Rossi, S | 1 |
| Barton, JK; Welge, WA | 1 |
| Barton, JK; Bommireddy, R; Harpel, K; Jones, M; Leung, S; Rice, PF | 1 |
| Brembeck, FH; Talla, SB | 1 |
| Chan, AWH; Chan, FKL; Chu, ESH; Nakatsu, G; Ng, SC; Sheng, J; Sung, JJY; Tsoi, H; Yu, J; Zhang, X | 1 |
| Chan, JY; Cheung, WK; Hao, X; Huang, MT; Khor, TO; Kong, AN; Liu, Y; Prawan, A; Reddy, BS; Yang, CS; Yu, S | 1 |
| Braun, U; Fields, AP; Leitges, M; Murray, NR; Weems, J | 1 |
| Hao, X; Ju, J; Lambert, JD; Lee, MJ; Lu, G; Newmark, HL; Xiao, H; Yang, CS | 1 |
| Issa, AY; Muga, SJ; Nitcheva, D; Smith, T; Volate, SR; Wargovich, MJ | 2 |
| Begleiter, A; Bird, RP; Lefas, GM; Maksymiuk, AW; Sivananthan, K | 1 |
| Chen, J; Huang, XF | 1 |
| Koketsu, M; Oyama, T; Sugie, S; Tanaka, T; Watanabe, K; Yasui, Y | 1 |
| Barney, KA; Blevins, EA; Finkelman, FD; Flick, MJ; Harmel-Laws, E; Horowitz, NA; Kombrinck, KW; Palumbo, JS; Pinkerton, MD; Shaw, MA; Steinbrecher, KA; Talmage, KE; Witte, DP | 1 |
| Cheng, AC; Ho, CT; Lai, CS; Li, S; Lo, CY; Pan, MH; Tsai, ML; Wang, Y; Wang, YJ; Xiao, H | 1 |
| Backman, V; Brasky, J; Cornwell, ML; Crawford, SE; De La Cruz, M; Gibson, TP; Gomes, A; Kunte, DP; Mutyal, N; Radosevich, A; Roy, HK; Ruderman, S; Stypula, Y; Tiwari, AK; Wali, RK | 1 |
| Erwin, CR; Guo, J; Liu, J; Schneider, JE; Stappenbeck, TS; Wakeman, D; Wandu, WS; Warner, BW | 1 |
| Clarke, M; Das, S; Huels, D; Jamieson, T; Jung, A; Neumann, J; Nibbs, RJ; Olson, MF; Samuel, MS; Sansom, OJ; Steele, CW | 1 |
| Hara, A; Hatano, Y; Hirata, A; Hirose, Y; Kuno, T; Masuda, S; Mori, H; Tanaka, T; Terasaki, M; Tomita, H | 1 |
| Aadland, E; Fagerhol, MK; Kristinsson, J; Nygaard, K; Sundseth, A | 1 |
| Biggeri, A; Caderni, G; Clune, Y; Collins, KJ; Dolara, P; Femia, AP; Giannini, A; Luceri, C; Paglierani, M; Salvadori, M | 1 |
| Fujihara, H; Kamada, N; Kusuoka, O; Masutani, M; Nakagama, H; Nakamoto, K; Nozaki, T; Sugimura, T; Suzuki, H; Tsutsumi, M; Watanabe, M | 1 |
| Kohno, H; Mori, H; Sugie, S; Suzuki, R; Tanaka, T; Yamada, Y | 1 |
| Katayama, M; Kondo, K; Nozawa, H; Sonobe, H; Tajima, O; Wakabayashi, K; Yoshida, A | 1 |
| Iwasaki, Y; Kameue, C; Koyama, H; Nakayama, K; Tsukahara, T; Ushida, K; Yamada, K | 1 |
| Hara, A; Hata, K; Hirose, Y; Kuno, T; Mori, H; Qiang, SH; Yamada, Y | 1 |
| Kawamori, T; Kitamura, T; Maruyama, T; Narumiya, S; Sugimura, T; Uchiya, N; Wakabayashi, K; Watanabe, K | 1 |
| Backman, V; Goldberg, MJ; Kim, YL; Koetsier, JL; Kunte, DP; Liu, Y; Roy, HK; Turzhitsky, V; Wali, RK | 1 |
| Kohno, H; Nakagama, H; Sugie, S; Suzuki, R; Tanaka, T | 1 |
| Bissonnette, M; Cerda, S; Cohen, G; Dougherty, U; Fichera, A; Gong, C; Hart, J; Jagadeeswaran, S; Joseph, L; Khare, S; Little, N; Mustafi, R; Sehdev, A; Tallerico, M; Tretiakova, M; Turner, JR; Yuan, W | 1 |
| Barton, JK; Besselsen, DG; Drexler, W; Gerner, EW; Hariri, LP; Hermann, B; Ignatenko, NA; McNally, J; Povazay, B; Qiu, Z; Sattmann, H; Tumlinson, AR; Unterhuber, A | 1 |
| Burch, RP; Chen, X; Dove, WF; Halberg, RB | 1 |
| Albert, PS; Barrett, KG; Bennink, MR; Bobe, G; Colburn, NH; Lanza, E; Mentor-Marcel, RA; Saffiotti, U; Young, MR | 1 |
| Mori, H; Nicolais, M; Reddy, BS | 1 |
| Maeura, Y; Reddy, BS | 1 |
| Cooke, T; Goeting, N; Inman, C; Kirkham, N; Stainthorp, DH; Taylor, I | 1 |
| Bird, RP | 1 |
| Baba, M; Iishi, H; Nakaizumi, A; Tatsuta, M; Uehara, H; Yamamoto, R | 1 |
| Chen, CD; Harris, C; Velasco, M; Wargovich, MJ; Yang, E | 1 |
| Cosenza, V; D'Argenio, G; D'Armiento, FP; De Ritis, F; Delle Cave, M; Iovino, P; Mazzacca, G; Sorrentini, I | 1 |
| Conney, AH; Huang, MT; Lou, YR; Ma, W; Newmark, HL; Reuhl, KR | 1 |
| Biggeri, A; Caderni, G; Dolara, P; Giannini, A; Luceri, C; Spagnesi, MT | 1 |
| Kelloff, G; Rao, CV; Reddy, BS; Rivenson, A | 1 |
| Kojima, T; Mori, H; Suzui, M; Tanaka, T | 1 |
| Ghose, T; Reddy, BS; Rijhsinghani, K | 1 |
| Bruce, WR; Gallinger, S; Hay, K; Medline, A; Shpitz, B; Stern, HS; Vivona, AA; Ward, MA | 1 |
| Barnes, LH; Kelloff, GV; Lubet, RA; Pereira, MA; Steele, VE | 1 |
| Aquino, B; Bissonnette, M; Brasitus, TA; Khare, S; Niedziela, S; Sitrin, M; Wali, RK | 1 |
| Alabaster, O; Frost, A; Shivapurkar, N; Tang, ZC | 1 |
| Asamoto, M; Baba-Toriyama, H; Kakizoe, T; Kim, DJ; Krutovskikh, V; Masuda, M; Moore, MA; Nakamura, J; Nishino, H; Ota, T; Sekine, K; Sugimoto, H; Takasuka, N; Tsuda, H; Watanabe, E | 1 |
| Biggeri, A; Brighenti, F; Caderni, G; Cresci, A; Dolara, P; Fazi, M; Giannini, A; Lancioni, L; Luceri, C; Orpianesi, C | 1 |
| Ganthavorn, C; Hughes, JS; Wilson-Sanders, S | 1 |
| Ahnen, D; Driggers, L; Maltzman, T; Stephens, J; Whittington, J | 1 |
| Alink, GM; Hollanders, VM; Koeman, JH; Rijnkels, JM; Woutersen, RA | 1 |
| Beauchamp, RD; DuBois, RN; Oshima, M; Pereira, MA; Reynolds, AB; Shao, J; Sheng, H; Taketo, MM; Washington, MK; Williams, CS | 1 |
| Bazzicalupo, M; Briani, C; Caderni, G; De Filippo, C; Dolara, P; Fazi, M; Giannini, A | 1 |
| Kelloff, GJ; Kramer, PM; Lubet, RA; Pereira, MA; Steele, VE; Zheng, Y | 1 |
| Di Betta, E; Fontana, MG; Ghirardi, M; Nascimbeni, R; Salerni, B; Villanacci, V | 1 |
| Hara, A; Honjo, S; Kakumoto, M; Kawabata, K; Makita, H; Mori, H; Tanaka, T; Tsuda, H; Ushida, J | 1 |
| Kawamori, T; Kelloff, G; Lubet, R; Rao, CV; Reddy, BS; Steele, V | 1 |
| Kelloff, GJ; Kramer, PM; Li, H; Lubet, RA; Pereira, MA; Steele, VE | 1 |
| Hirose, Y; Kelloff, GJ; Lubet, RA; Rao, CV; Reddy, BS; Steele, VE | 1 |
| Duranton, B; Ellmerich, S; Galluser, M; Gossé, F; Klein, JP; Raul, F; Schöller, M | 1 |
| Baba, M; Iishi, H; Nakaizumi, A; Sakai, N; Tatsuta, M; Uehara, H; Yano, H | 1 |
| Kawamori, T; Mutoh, M; Sugimura, T; Takahashi, M; Wakabayashi, K | 1 |
| Given, R; Singh, P; Varro, A; Velasco, M; Wang, TC | 1 |
| Nambiar, PR; Papanikolaou, A; Rosenberg, DW; Wang, QS | 1 |
| Azuma, Y; Kagami, S; Kohno, H; Murakami, M; Ogawa, H; Shimada, R; Sumida, T; Tanaka, T | 1 |
| Caderni, G; De Filippo, C; Dolara, P; Gambacciani, L; Giannini, A; Luceri, C; Salvadori, M | 1 |
| Biggeri, A; Caderni, G; Cheynier, V; De Filippo, C; Dolara, P; Giannini, A; Luceri, C; Remy, S; Salvadori, M | 1 |
| Le Leu, RK; McIntosh, GH; Young, GP | 1 |
| McIntosh, GH; Pointing, G; Royle, PJ | 1 |
| Alexander, J; Husøy, T; Løberg, EM; Namork, E; Paulsen, JE; Steffensen, IL | 1 |
| Cui, H; Giardina, C; Guda, K; Nambiar, P; Rosenberg, DW | 1 |
| Kohno, H; Takashima, S; Tanaka, T; Yoshitani, SI | 1 |
| Boggio, M; Borrelli, F; Capasso, F; Izzo, AA; Mascolo, N; Massa, B; Mereto, E; Orsi, P; Sini, D | 1 |
| den, BM; Diederichsen, A; Fenger, C; Hansen, K; Kobaek-Larsen, M; Nissen, I; Ritskes-Hoitinga, M; Thorup, I; Vach, W | 1 |
| Frankel, WL; Gallaher, DD; Gupta, A; Habib, SG; Harris, GK; Kresty, LA; LaPerle, K; Nines, RG; Schwartz, SJ; Stoner, GD | 1 |
| Moriwaki, H; Nakagama, H; Okuno, M; Suzui, M; Tanaka, T | 1 |
| Baba, M; Iishi, H; Taniguchi, H; Tatsuta, M | 5 |
| Archer, MC; Bruce, WR; Chan, CC; Corpet, DE; Medline, A; Roncucci, L; Stamp, D; Zhang, XM | 1 |
| Baba, M; Iishi, H; Okuda, S; Taniguchi, H; Tatsuta, M | 1 |
| Baba, M; Ichii, M; Iishi, H; Nakaizumi, A; Taniguchi, H; Tatsuta, M; Uehara, H | 1 |
| Bell, PR; Clayton, HA; Neoptolemos, JP; Nicholson, ML; Talbot, IC | 1 |
| Baba, M; Iishi, H; Taniguchi, H; Tasuta, M | 1 |
| Archer, MC; Bruce, WR; Corpet, DE; Medline, A; Minkin, S; Stamp, D | 1 |
| Donegan, WL; Kusama, K; Samter, TG | 1 |
| El-Bayoumy, K; Reddy, BS; Tanaka, T | 1 |
| Reddy, BS; Tanaka, T | 1 |
| Goeting, NL; Taylor, I; Trotter, GA | 1 |
| Cooke, T; Goeting, N; Kirkham, N; Taylor, I; Trotter, GA | 1 |
2 review(s) available for azoxymethane and Adenoma
| Article | Year |
|---|---|
The signal pathways in azoxymethane-induced colon cancer and preventive implications.
Topics: Adenocarcinoma; Adenoma; Adiponectin; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogens; Colonic Neoplasms; Cytochrome P-450 CYP2E1; Diet; DNA Damage; Genes, ras; Humans; MAP Kinase Signaling System; Methylazoxymethanol Acetate; Mice; Mice, Knockout; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Transforming Growth Factor beta; Transforming Growth Factor beta2 | 2009 |
Role of aberrant crypt foci in understanding the pathogenesis of colon cancer.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Cholic Acid; Cholic Acids; Colon; Colonic Neoplasms; Dietary Fats; Dimethylhydrazines; Genes, ras; Humans; Intestinal Mucosa; Precancerous Conditions | 1995 |
116 other study(ies) available for azoxymethane and Adenoma
| Article | Year |
|---|---|
Disruption of the crypt niche promotes outgrowth of mutated colorectal tumor stem cells.
Topics: Adenoma; Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Humans; Mice; Neoplastic Stem Cells | 2022 |
6- shogaol suppresses AOM/DSS-mediated colorectal adenoma through its antioxidant and anti-inflammatory effects in mice.
Topics: Adenoma; Animals; Anti-Inflammatory Agents; Antioxidants; Azoxymethane; Colonic Neoplasms; Colorectal Neoplasms; Disease Models, Animal; Inflammation; Male; Mice | 2022 |
Intermittent Dosing Regimens of Aspirin and Naproxen Inhibit Azoxymethane-Induced Colon Adenoma Progression to Adenocarcinoma and Invasive Carcinoma.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azoxymethane; Carcinogens; Colonic Neoplasms; Dose-Response Relationship, Drug; Male; Naproxen; Neoplasm Invasiveness; Rats; Rats, Wistar | 2019 |
An Optimized Protocol of Azoxymethane-Dextran Sodium Sulfate Induced Colorectal Tumor Model in Mice.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Body Weight; Carcinogenesis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Male; Mice, Inbred C57BL | 2019 |
Proton Pump Inhibitor Omeprazole Suppresses Carcinogen-induced Colonic Adenoma Progression to Adenocarcinoma in F344 Rat.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Omeprazole; Proton Pump Inhibitors; Rats; Rats, Inbred F344 | 2021 |
Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colitis; Colonic Neoplasms; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dextran Sulfate; Disease Progression; Epigenesis, Genetic; Histone Deacetylases; Homeostasis; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Neutrophils; Receptors, G-Protein-Coupled | 2018 |
A Novel Modification of the AOM/DSS Model for Inducing Intestinal Adenomas in Mice.
Topics: Adenoma; Animals; Azoxymethane; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Humans; Intestinal Neoplasms; Mice, Inbred C57BL | 2018 |
Geminin ablation in vivo enhances tumorigenesis through increased genomic instability.
Topics: Adenoma; Animals; Ataxia Telangiectasia Mutated Proteins; Azoxymethane; Carcinoma; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Geminin; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Genomic Instability; Histones; Lung Neoplasms; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Phosphorylation; Urethane | 2018 |
Deletion of cadherin-17 enhances intestinal permeability and susceptibility to intestinal tumour formation.
Topics: Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Adenoma; Animals; Azoxymethane; Cadherins; Carcinoma; Cell Cycle Proteins; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gene Deletion; Genetic Predisposition to Disease; Intestinal Absorption; Intestinal Mucosa; Mice, Inbred C57BL; Mice, Knockout; Permeability; Phenotype; Phosphoproteins; Signal Transduction; Tumor Suppressor Proteins; YAP-Signaling Proteins | 2018 |
A novel mouse model of sporadic colon cancer induced by combination of conditional Apc genes and chemical carcinogen in the absence of Cre recombinase.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colonic Neoplasms; Disease Models, Animal; Genes, APC; Integrases; Mice; Mice, Inbred C57BL | 2019 |
Biological mechanisms underlying structural changes induced by colorectal field carcinogenesis measured with low-coherence enhanced backscattering (LEBS) spectroscopy.
Topics: Adenoma; Animals; Azoxymethane; Cluster Analysis; Colchicine; Colonic Neoplasms; Cytoskeleton; Intestinal Mucosa; Light; Rats; Rats, Inbred F344; Rectum; Scattering, Radiation; Spectrophotometry; Transcriptome; Tubulin Modulators | 2013 |
Diet-induced obesity promotes colon tumor development in azoxymethane-treated mice.
Topics: Aberrant Crypt Foci; Adenoma; Animals; Azoxymethane; Colon; Colonic Neoplasms; Diet, High-Fat; Interferon-gamma; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Obesity; Risk Factors; Tumor Necrosis Factor-alpha | 2013 |
Suppression of β-catenin and cyclooxygenase-2 expression and cell proliferation in azoxymethane-induced colonic cancer in rats by rice bran phytic acid (PA).
Topics: Adenoma; Animals; Apoptosis; Azoxymethane; beta Catenin; Blotting, Western; Carcinogens; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Immunoenzyme Techniques; Male; Oryza; Phytic Acid; Rats; Rats, Sprague-Dawley | 2013 |
Deletion of glutathione peroxidase-2 inhibits azoxymethane-induced colon cancer development.
Topics: Adenoma; Animals; Antioxidants; Apoptosis; Azoxymethane; beta Catenin; Carcinogenesis; Colonic Neoplasms; Diet; Dietary Supplements; Epithelial Cells; Gene Deletion; Glutathione Peroxidase; Humans; Intestinal Mucosa; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Selenium | 2013 |
Nano-architectural alterations in mucus layer fecal colonocytes in field carcinogenesis: potential for screening.
Topics: Adenoma; Animals; Azoxymethane; Carcinogenesis; Colon; Colonoscopy; Colorectal Neoplasms; Disease Models, Animal; Early Detection of Cancer; Endoscopy; Feces; Intestinal Mucosa; Male; Mass Screening; Microscopy; Occult Blood; Optics and Photonics; Rats; Rats, Inbred F344 | 2013 |
3-aroylmethylene-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-ones as potent Nrf2/ARE inducers in human cancer cells and AOM-DSS treated mice.
Topics: Active Transport, Cell Nucleus; Adenoma; Animals; Antineoplastic Agents; Antioxidant Response Elements; Azoxymethane; Blotting, Western; Cell Nucleus; Colorectal Neoplasms; Dextran Sulfate; Female; Gene Expression Regulation, Neoplastic; HCT116 Cells; Heme Oxygenase-1; Hep G2 Cells; Heterocyclic Compounds, 3-Ring; Humans; Interleukin-1beta; Interleukin-6; Mice; Mice, Inbred C57BL; Models, Chemical; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Neoplasms; NF-E2-Related Factor 2 | 2013 |
Chemopreventive efficacy of raloxifene, bexarotene, and their combination on the progression of chemically induced colon adenomas to adenocarcinomas in rats.
Topics: Adenocarcinoma; Adenoma; Adult; Aged; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Bexarotene; Biomarkers, Tumor; Blotting, Western; Colonic Neoplasms; Drug Therapy, Combination; Estrogen Antagonists; Estrogen Receptor beta; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Neoplasm Grading; Raloxifene Hydrochloride; Rats; Rats, Inbred F344; Real-Time Polymerase Chain Reaction; Retinoid X Receptors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrahydronaphthalenes; Tissue Array Analysis; Tumor Cells, Cultured | 2013 |
Bovine milk-derived α-lactalbumin inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sodium sulfate-treated mice.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Carcinogenesis; Cattle; Colon; Colonic Neoplasms; Dextran Sulfate; Dietary Supplements; Dinoprostone; Inflammation; Interleukin-1beta; Lactalbumin; Male; Mice; Mice, Inbred C57BL; Milk; Occult Blood; Organ Size; Tumor Necrosis Factor-alpha | 2014 |
Role of inflammation and inflammatory mediators in colorectal cancer.
Topics: Adenoma; Animals; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Genes, APC; Humans; Inflammation Mediators; Intestinal Mucosa; Mice, Inbred BALB C; Mice, Knockout; Rats; Receptors, Interleukin-8B | 2014 |
Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones.
Topics: Adenoma; Adenomatous Polyposis Coli; Animals; Animals, Congenic; Azoxymethane; Carcinogens; Colonic Neoplasms; Dihydrotestosterone; Disease Models, Animal; Estradiol; Female; Genes, APC; Gonadal Steroid Hormones; Hormone Replacement Therapy; Humans; Male; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mutation; Neoplasms, Hormone-Dependent; Orchiectomy; Organ Specificity; Ovariectomy; Postmenopause; Random Allocation; Rats; Rats, Inbred F344; Rats, Mutant Strains; Receptors, Androgen; RNA, Messenger; Sex Distribution; Species Specificity | 2014 |
Dual optical modality endoscopic imaging of cancer development in the mouse colon.
Topics: Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Colonoscopy; Coloring Agents; Female; Methylene Blue; Mice; Observer Variation; Sensitivity and Specificity; Tomography, Optical Coherence | 2015 |
NF-κB1, NF-κB2 and c-Rel differentially regulate susceptibility to colitis-associated adenoma development in C57BL/6 mice.
Topics: Adenoma; Animals; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; Disease Susceptibility; Epithelial Cells; Female; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B p50 Subunit; NF-kappa B p52 Subunit; Proto-Oncogene Proteins c-rel; Signal Transduction | 2015 |
Strawberry phytochemicals inhibit azoxymethane/dextran sodium sulfate-induced colorectal carcinogenesis in Crj: CD-1 mice.
Topics: Adenocarcinoma; Adenoma; Animals; Anthocyanins; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Ellagic Acid; Flavonols; Fragaria; Fruit; Functional Food; Inflammation Mediators; Male; Mice, Inbred ICR; Phytochemicals; Phytotherapy | 2015 |
The MUTYH base excision repair gene protects against inflammation-associated colorectal carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Bone Marrow Cells; CD8-Positive T-Lymphocytes; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; DNA Glycosylases; Forkhead Transcription Factors; Guanine; Inflammation Mediators; Mice, Knockout; T-Lymphocytes, Regulatory; Time Factors | 2015 |
Expanding Functionality of Commercial Optical Coherence Tomography Systems by Integrating a Custom Endoscope.
Topics: Adenoma; Algorithms; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Endoscopes; Endoscopy; Mice, Inbred Strains; Models, Theoretical; Reproducibility of Results; Sensitivity and Specificity; Tomography, Optical Coherence | 2015 |
Imaging colon cancer development in mice: IL-6 deficiency prevents adenoma in azoxymethane-treated Smad3 knockouts.
Topics: Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Interleukin-6; Male; Mice; Smad3 Protein; Tomography, Optical Coherence | 2016 |
The role of Pygo2 for Wnt/ß-catenin signaling activity during intestinal tumor initiation and progression.
Topics: Adenoma; Animals; Azoxymethane; beta Catenin; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Disease Models, Animal; Disease Progression; Gene Expression Regulation, Neoplastic; Genes, APC; Genetic Predisposition to Disease; Intracellular Signaling Peptides and Proteins; Mice, Inbred C57BL; Mice, Knockout; Mutation; Phenotype; Proto-Oncogene Proteins c-myc; Time Factors; Tumor Burden; Wnt Signaling Pathway | 2016 |
Peptostreptococcus anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice.
Topics: Acetophenones; Adenoma; Aged; AMP-Activated Protein Kinases; Animals; Azoxymethane; Biopsy; Biosynthetic Pathways; Caco-2 Cells; Case-Control Studies; Cell Proliferation; Cholesterol; Colon; Colonic Neoplasms; DNA, Bacterial; Enzyme Inhibitors; Feces; Gene Expression; Gram-Positive Bacterial Infections; HT29 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Peptostreptococcus; Reactive Oxygen Species; Signal Transduction; Sterol Regulatory Element Binding Protein 2; Toll-Like Receptor 2; Toll-Like Receptor 4; Up-Regulation | 2017 |
Increased susceptibility of Nrf2 knockout mice to colitis-associated colorectal cancer.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Cytoprotection; Dextran Sulfate; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2 | 2008 |
Protein kinase C betaII and PKCiota/lambda: collaborating partners in colon cancer promotion and progression.
Topics: Adenoma; Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colonic Neoplasms; Disease Progression; Genes, APC; Humans; Isoenzymes; Mice; Mice, Knockout; Mice, Transgenic; Protein Kinase C; Protein Kinase C beta | 2009 |
A gamma-tocopherol-rich mixture of tocopherols inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sulfate sodium-treated mice.
Topics: Adenocarcinoma; Adenoma; Animals; Antioxidants; Apoptosis; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Colon; Colonic Neoplasms; Dextran Sulfate; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; gamma-Tocopherol; Inflammation; Leukotriene B4; Male; Mice; Tyrosine | 2009 |
Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer.
Topics: Adenoma; Animals; Azoxymethane; beta Catenin; Camellia sinensis; Carcinogens; Cyclin D1; Disease Models, Animal; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Genes, APC; Immunoenzyme Techniques; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Promoter Regions, Genetic; Retinoid X Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tea | 2009 |
Inhibition of colon carcinogenesis by post-initiation induction of NQO1 in Sprague-Dawley rats.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Enzyme Induction; Glucuronosyltransferase; Glutathione Transferase; Intestinal Mucosa; Male; NAD(P)H Dehydrogenase (Quinone); Neoplasms, Experimental; Precancerous Conditions; Pyrazines; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes; Time Factors | 2009 |
Dietary tricin suppresses inflammation-related colon carcinogenesis in male Crj: CD-1 mice.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Blotting, Western; Carcinogens; Colonic Neoplasms; Diet; Flavonoids; Inflammation; Male; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
Colitis-associated cancer is dependent on the interplay between the hemostatic and inflammatory systems and supported by integrin alpha(M)beta(2) engagement of fibrinogen.
Topics: Adenoma; Animals; Azoxymethane; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Disease Progression; Fibronectins; Hemostasis; Macrophage-1 Antigen; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic | 2010 |
Chemoprevention of colonic tumorigenesis by dietary hydroxylated polymethoxyflavones in azoxymethane-treated mice.
Topics: Aberrant Crypt Foci; Adenoma; Animals; Apoptosis; Azoxymethane; Carcinogens; Citrus sinensis; Colon; Colonic Neoplasms; Cyclooxygenase 2; Diet; Flavones; Fruit; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Inbred ICR; Nitric Oxide Synthase Type II; Random Allocation; RNA, Messenger; Signal Transduction; Time Factors | 2011 |
Neo-angiogenesis and the premalignant micro-circulatory augmentation of early colon carcinogenesis.
Topics: Adenoma; Animals; Azoxymethane; Biomarkers, Tumor; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Gene Expression Profiling; Intestinal Mucosa; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2011 |
Deletion of p38-alpha mitogen-activated protein kinase within the intestinal epithelium promotes colon tumorigenesis.
Topics: Adenoma; Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Enterocytes; Feces; Intestinal Mucosa; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 14; Weight Loss | 2012 |
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Animals, Inbred Strains; Azoxymethane; Cell Transformation, Neoplastic; Chemokines, CXC; Colitis; Colonic Neoplasms; Dermatitis, Contact; Dextran Sulfate; Gene Expression; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Papilloma; Peroxidase; Precancerous Conditions; Receptors, Interleukin-8B; Skin Neoplasms; Statistics, Nonparametric; Tetradecanoylphorbol Acetate; Tumor Burden | 2012 |
Organomagnesium suppresses inflammation-associated colon carcinogenesis in male Crj: CD-1 mice.
Topics: Adenocarcinoma; Adenoma; Animals; Apoptosis; Azoxymethane; Blotting, Western; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Humans; Immunoenzyme Techniques; Inflammation; Interferon-gamma; Interleukin-1beta; Interleukin-6; Magnesium Compounds; Male; Mice; Mice, Inbred ICR; Mitotic Index; Organometallic Compounds; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2013 |
Comparison of faecal and intestinal concentrations of granulocyte marker protein and localization of gastrointestinal tumours in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Biomarkers, Tumor; Carcinogens; Enzyme-Linked Immunosorbent Assay; Feces; Gastrointestinal Neoplasms; Intestinal Mucosa; Leukocyte L1 Antigen Complex; Models, Animal; Rats; Rats, Sprague-Dawley | 2002 |
Antitumorigenic activity of the prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis on azoxymethane-induced colon carcinogenesis in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azoxymethane; Bifidobacterium; Carcinogens; Cecum; Cell Division; Colonic Neoplasms; Cyclooxygenase 2; Diet; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Induction; Fatty Acids, Volatile; Gastrointestinal Contents; Glutathione S-Transferase pi; Glutathione Transferase; Intestinal Mucosa; Inulin; Isoenzymes; Lactobacillus; Male; Neoplasm Proteins; Oligosaccharides; Probiotics; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344 | 2002 |
Parp-1 deficiency implicated in colon and liver tumorigenesis induced by azoxymethane.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; beta Catenin; Carcinogens; Cell Transformation, Neoplastic; Colonic Neoplasms; Cytoskeletal Proteins; Disease Progression; DNA Primers; Female; Homozygote; Liver Neoplasms, Experimental; Mice; Mice, Inbred ICR; Mice, Knockout; Poly(ADP-ribose) Polymerases; Trans-Activators | 2003 |
A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate.
Topics: Adenocarcinoma; Adenoma; Animals; Anticoagulants; Azoxymethane; beta Catenin; Carcinogens; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Dextran Sulfate; Disease Models, Animal; Inflammation; Injections, Intraperitoneal; Isoenzymes; Male; Mast Cells; Mice; Mice, Inbred ICR; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Trans-Activators; Tumor Suppressor Protein p53 | 2003 |
Intake of beer inhibits azoxymethane-induced colonic carcinogenesis in male Fischer 344 rats.
Topics: Adenocarcinoma; Adenoma; Administration, Oral; Animals; Azoxymethane; Beer; Body Weight; Carcinogens; Colonic Neoplasms; Comet Assay; DNA Damage; Intestinal Mucosa; Male; Rats; Rats, Inbred F344 | 2004 |
Dietary sodium gluconate protects rats from large bowel cancer by stimulating butyrate production.
Topics: Adenocarcinoma; Adenoma; Animals; Apoptosis; Azoxymethane; beta Catenin; Butyrates; Carcinogens; Cecum; Colon; Colorectal Neoplasms; Cytoskeletal Proteins; Deoxycholic Acid; Diet; Gluconates; Immunohistochemistry; In Situ Nick-End Labeling; Intestines; Male; Organ Size; Rats; Rats, Inbred F344; Trans-Activators | 2004 |
Tumor formation is correlated with expression of beta-catenin-accumulated crypts in azoxymethane-induced colon carcinogenesis in mice.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; beta Catenin; Biomarkers, Tumor; Carcinogens; Colonic Neoplasms; Cytoskeletal Proteins; Genetic Predisposition to Disease; Intestinal Mucosa; Mice; Mice, Inbred AKR; Mucins; Neoplasm Proteins; Specific Pathogen-Free Organisms; Trans-Activators | 2004 |
Prostaglandin E receptor subtype EP(1) deficiency inhibits colon cancer development.
Topics: Adenocarcinoma; Adenoma; Animals; Apoptosis; Azoxymethane; Cell Proliferation; Colonic Neoplasms; Mice; Mice, Knockout; Protein Kinase C; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype | 2005 |
Increased microvascular blood content is an early event in colon carcinogenesis.
Topics: Adenoma; Animals; Azoxymethane; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Disease Models, Animal; Disease Progression; Hemoglobins; Humans; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Microcirculation; Optics and Photonics; Pilot Projects; Precancerous Conditions; Rats; Rats, Inbred F344; Scattering, Radiation | 2005 |
Strain differences in the susceptibility to azoxymethane and dextran sodium sulfate-induced colon carcinogenesis in mice.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Dextran Sulfate; Disease Susceptibility; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA | 2006 |
Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis.
Topics: Adenoma; Animals; Azoxymethane; beta Catenin; Carcinogens; Cell Transformation, Neoplastic; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; ErbB Receptors; Gefitinib; Genes, ras; Male; Mice; Mice, Inbred A; Mutation; Quinazolines; Signal Transduction; Up-Regulation | 2007 |
Green tea selectively targets initial stages of intestinal carcinogenesis in the AOM-ApcMin mouse model.
Topics: Adenoma; Animals; Azoxymethane; Camellia sinensis; Carcinogens; Colonic Neoplasms; Cyclooxygenase 2; Female; Gene Expression Regulation, Neoplastic; Genes, APC; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Plant Extracts | 2007 |
Serial endoscopy in azoxymethane treated mice using ultra-high resolution optical coherence tomography.
Topics: Adenoma; Animals; Azoxymethane; Colon; Colorectal Neoplasms; Disease Models, Animal; Disease Progression; Endoscopy, Gastrointestinal; Gastrointestinal Neoplasms; Mice; Tomography, Optical Coherence | 2007 |
Intestinal adenomagenesis involves core molecular signatures of the epithelial-mesenchymal transition.
Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; Cadherins; Cell Proliferation; Epithelium; Fibronectins; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Intestinal Neoplasms; Intestinal Polyps; Mesoderm; Mice; Mutation; Neoplasm Invasiveness; Phenotype; ras Proteins; Signal Transduction; Snail Family Transcription Factors; Transcription Factors; Transforming Growth Factor beta; Vimentin; Wnt Proteins | 2008 |
Dietary cooked navy beans and their fractions attenuate colon carcinogenesis in azoxymethane-induced ob/ob mice.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colonic Neoplasms; Fabaceae; Male; Mice; Mice, Obese; Plant Extracts; Random Allocation; Solubility | 2008 |
Effect of dietary wheat bran and dehydrated citrus fiber on azoxymethane-induced intestinal carcinogenesis in Fischer 344 rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azo Compounds; Azoxymethane; Cellulose; Colonic Neoplasms; Dietary Fiber; Edible Grain; Fruit; Intestinal Neoplasms; Male; Neoplasms, Experimental; Rats; Rats, Inbred F344 | 1981 |
Tumor promotion by dietary fat in azoxymethane-induced colon carcinogenesis in female F344 rats: influence of amount and source of dietary fat.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Body Weight; Colonic Neoplasms; Dietary Fats; Feces; Female; Intestinal Neoplasms; Oils; Rats; Rats, Inbred F344; Sterols | 1984 |
Detection of early neoplastic changes in experimentally induced colorectal cancer using scanning electron microscopy and cell kinetic studies.
Topics: Adenoma; Animals; Azoxymethane; Cell Division; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; Microscopy, Electron, Scanning; Precancerous Conditions; Rats; Rats, Inbred Strains; Rectal Neoplasms | 1984 |
Attenuation of vasoactive intestinal peptide enhancement of colon carcinogenesis by ornithine decarboxylase inhibitor.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Diamines; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Random Allocation; Rats; Rats, Wistar; Vasoactive Intestinal Peptide | 1995 |
Inhibition of aberrant crypt growth by non-steroidal anti-inflammatory agents and differentiation agents in the rat colon.
Topics: Acetaminophen; Adenoma; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Azoxymethane; Colonic Neoplasms; Drug Screening Assays, Antitumor; Fenretinide; Ibuprofen; Isotretinoin; Male; Piroxicam; Precancerous Conditions; Rats; Rats, Inbred F344 | 1995 |
Transglutaminase in azoxymethane-induced colon cancer in the rat.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colon; Colonic Neoplasms; Immunoenzyme Techniques; Intestine, Small; Male; Rats; Rats, Sprague-Dawley; Transglutaminases | 1995 |
Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice.
Topics: Adenocarcinoma; Adenoma; Adenoma, Villous; Animals; Azoxymethane; Benzo(a)pyrene; Carcinogens; Colonic Neoplasms; Curcumin; Duodenal Neoplasms; Female; Male; Methylnitronitrosoguanidine; Mice; Stomach Neoplasms | 1994 |
Dietary carbohydrates modify azoxymethane-induced intestinal carcinogenesis in rats.
Topics: Adenocarcinoma; Adenoma; Amylose; Animals; Azoxymethane; Calcium; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Intestinal Neoplasms; Male; Rats; Rats, Sprague-Dawley; Starch | 1994 |
Inhibitory effect of aspirin on azoxymethane-induced colon carcinogenesis in F344 rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Aspirin; Azoxymethane; Body Weight; Colonic Neoplasms; Dinoprostone; Male; Rats; Rats, Inbred F344 | 1993 |
Chemoprevention of colon carcinogenesis by the natural product of a simple phenolic compound protocatechuic acid: suppressing effects on tumor development and biomarkers expression of colon tumorigenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Antineoplastic Agents; Azoxymethane; Biomarkers, Tumor; Cell Division; Colon; Colonic Neoplasms; Drug Screening Assays, Antitumor; Hydroxybenzoates; Intestinal Mucosa; Liver; Male; Nucleolus Organizer Region; Organ Size; Ornithine Decarboxylase; Rats; Rats, Inbred F344 | 1993 |
Alpha 1-antitrypsin as a biomarker in azoxymethane induced intestinal tumors in F344 rats.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoma; alpha 1-Antitrypsin; Animals; Azoxymethane; Biomarkers, Tumor; Colonic Neoplasms; Intestinal Neoplasms; Intestine, Small; Male; Rats; Rats, Inbred F344; Sensitivity and Specificity | 1993 |
K-ras mutations in aberrant crypt foci, adenomas and adenocarcinomas during azoxymethane-induced colon carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Base Sequence; Blotting, Southern; Colon; Colonic Neoplasms; Female; Genes, ras; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred F344 | 1993 |
Piroxicam-induced regression of azoxymethane-induced aberrant crypt foci and prevention of colon cancer in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Drug Screening Assays, Antitumor; Male; Piroxicam; Precancerous Conditions; Rats; Rats, Inbred F344 | 1996 |
Protein kinase C isoforms in the chemopreventive effects of a novel vitamin D3 analogue in rat colonic tumorigenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Azoxymethane; Calcitriol; Chemoprevention; Colon; Colonic Neoplasms; Down-Regulation; Isoenzymes; Male; Protein Kinase C; Rats; Rats, Inbred F344; Up-Regulation | 1996 |
The effect of dietary fat on the promotion of mammary and colon cancer in a dual-organ rat carcinogenesis model.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Dietary Fats; Energy Intake; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Inhibition of azoxymethane-initiated colon tumor by bovine lactoferrin administration in F344 rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinoma; Cattle; Colonic Neoplasms; Incidence; Intestinal Neoplasms; Intestine, Large; Intestine, Small; Lactoferrin; Male; Rats; Rats, Inbred F344 | 1997 |
Modification of azoxymethane intestinal carcinogenesis in rats by feeding sucrose boluses, pasta, and glucose.
Topics: Adenoma; Animals; Azoxymethane; Body Weight; Carcinogens; Cecum; Cohort Studies; Dietary Carbohydrates; Dietary Sucrose; Fatty Acids, Volatile; Glucose; Injections, Subcutaneous; Intestinal Neoplasms; Male; Neoplasm Invasiveness; Rats; Rats, Inbred F344 | 1997 |
Dry beans inhibit azoxymethane-induced colon carcinogenesis in F344 rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Caseins; Colonic Neoplasms; Dietary Fiber; Fabaceae; Male; Plants, Medicinal; Rats; Rats, Inbred F344; Weight Gain | 1997 |
AOM-induced mouse colon tumors do not express full-length APC protein.
Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Azoxymethane; Carcinoma in Situ; Colonic Neoplasms; Cytoskeletal Proteins; Female; Fluorescent Antibody Technique, Indirect; Intestinal Polyps; Male; Mice; Molecular Weight; Mutation; Neoplasm Proteins; Neoplasms, Experimental | 1997 |
Absence of an inhibitory effect of a vegetables-fruit mixture on the initiation and promotion phases of azoxymethane-induced colorectal carcinogenesis in rats fed low- or high-fat diets.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Diet; Diet, Fat-Restricted; Dietary Fats; Fruit; Male; Rats; Rats, Inbred F344; Vegetables | 1998 |
Nuclear translocation of beta-catenin in hereditary and carcinogen-induced intestinal adenomas.
Topics: Adenoma; Animals; Azoxymethane; beta Catenin; Biological Transport; Carcinogens; Cell Nucleus; Cytoskeletal Proteins; Epithelial Cells; Female; Genes, APC; Humans; Intestinal Neoplasms; Male; Mice; Mice, Transgenic; Rats; Trans-Activators; Tumor Cells, Cultured | 1998 |
Mutations of the Apc gene in experimental colorectal carcinogenesis induced by azoxymethane in F344 rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colorectal Neoplasms; DNA, Neoplasm; Epithelium; Genes, APC; Intestinal Mucosa; Male; Mutation; Polymerase Chain Reaction; Precancerous Conditions; Rats; Rats, Inbred F344 | 1998 |
Effect of retinoids on AOM-induced colon cancer in rats: modulation of cell proliferation, apoptosis and aberrant crypt foci.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Body Weight; Carcinogens; Colon; Colonic Neoplasms; Drug Screening Assays, Antitumor; Fenretinide; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Tretinoin | 1999 |
Azoxymethane-induced aberrant crypt foci and colorectal tumors in F344 rats: sequential analysis of growth.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinoma, Signet Ring Cell; Cell Division; Colorectal Neoplasms; Hyperplasia; Intestinal Mucosa; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1999 |
Modifying effects of a flavonoid morin on azoxymethane-induced large bowel tumorigenesis in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Antioxidants; Azoxymethane; Carcinogens; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Glutathione Transferase; Male; Polyamines; Precancerous Conditions; Rats; Rats, Inbred F344 | 1999 |
Chemopreventive effect of S-methylmethane thiosulfonate and sulindac administered together during the promotion/progression stages of colon carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alkylating; Azoxymethane; Carcinogens; Colonic Neoplasms; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Male; Methyl Methanesulfonate; Rats; Rats, Inbred F344; Sulindac | 1999 |
Termination of piroxicam treatment and the occurrence of azoxymethane-induced colon cancer in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azoxymethane; Body Weight; Carcinogenicity Tests; Carcinogens; Cell Division; Colonic Neoplasms; Disease Progression; Drug Administration Schedule; Intestinal Mucosa; Male; Piroxicam; Precancerous Conditions; Rats; Rats, Inbred F344 | 1999 |
Lack of chemopreventive efficacy of DL-selenomethionine in colon carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Diet; Male; Rats; Rats, Inbred F344; Selenomethionine | 2000 |
Promotion of intestinal carcinogenesis by Streptococcus bovis.
Topics: Adenoma; Animals; Azoxymethane; Biogenic Polyamines; Cell Division; Cocarcinogenesis; Colon; Interleukin-8; Intestinal Neoplasms; Male; Precancerous Conditions; Rats; Rats, Wistar; Streptococcus bovis | 2000 |
ras p21 Isoprenylation inhibition induces flat colon tumors in Wistar rats.
Topics: Adenocarcinoma; Adenoma; Analysis of Variance; Animals; Antimetabolites; Apoptosis; Azoxymethane; Blotting, Western; Bromodeoxyuridine; Carcinogens; Colonic Neoplasms; Colonic Polyps; Genes, ras; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Oncogene Protein p21(ras); Point Mutation; Pravastatin; Prevalence; Protein Prenylation; Random Allocation; Rats; Rats, Wistar | 2000 |
Altered expression of beta-catenin, inducible nitric oxide synthase and cyclooxygenase-2 in azoxymethane-induced rat colon carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Gene Expression; Genes, ras; Hyperplasia; Isoenzymes; Male; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Subcellular Fractions; Trans-Activators | 2000 |
Progastrin expression predisposes mice to colon carcinomas and adenomas in response to a chemical carcinogen.
Topics: Adenoma; Amides; Animals; Azoxymethane; Carcinogens; Carcinoma; Colonic Neoplasms; Gastrins; Incidence; Mice; Mice, Transgenic; Neoplasms, Multiple Primary; Protein Precursors; Reference Values; Survival Analysis | 2000 |
Differential expression of p16(INK4a) in azoxymethane-induced mouse colon tumorigenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, p16; Genes, Retinoblastoma; Male; Mice; Mice, Inbred Strains; Neoplasm Proteins; Polymerase Chain Reaction; Precancerous Conditions; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm | 2000 |
Suppression of azoxymethane-induced colon carcinogenesis in male F344 rats by mandarin juices rich in beta-cryptoxanthin and hesperidin.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; beta Carotene; Beverages; Carcinogens; Citrus; Colonic Neoplasms; Cryptoxanthins; Cyclin D1; Hesperidin; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Xanthophylls | 2000 |
Detection of somatic DNA alterations in azoxymethane-induced F344 rat colon tumors by random amplified polymorphic DNA analysis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; DNA Damage; DNA Fingerprinting; DNA, Neoplasm; Genes, ras; Male; Microsatellite Repeats; Mutation; Precancerous Conditions; Random Amplified Polymorphic DNA Technique; Rats; Rats, Inbred F344 | 2000 |
Effects of black tea, green tea and wine extracts on intestinal carcinogenesis induced by azoxymethane in F344 rats.
Topics: Adenoma; Animals; Apoptosis; Azoxymethane; Body Weight; Carcinogens; Colon; Flavonoids; Intestinal Mucosa; Intestinal Neoplasms; Male; Phenols; Polymers; Polyphenols; Rats; Rats, Inbred F344; Tea; Wine | 2000 |
Folate deficiency reduces the development of colorectal cancer in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Colorectal Neoplasms; Folic Acid; Folic Acid Deficiency; Intestinal Neoplasms; Male; Rats; Rats, Sprague-Dawley | 2000 |
Wheat aleurone flour increases cecal beta-glucuronidase activity and butyrate concentration and reduces colon adenoma burden in azoxymethane-treated rats.
Topics: Adenoma; Animals; Azoxymethane; Butyrates; Carcinogens; Cecum; Cellulose; Colonic Neoplasms; Dietary Fiber; Feces; Fermentation; Flour; Glucuronidase; Hydrogen-Ion Concentration; Male; Rats; Rats, Sprague-Dawley; Triticum | 2001 |
Qualitative and quantitative relationship between dysplastic aberrant crypt foci and tumorigenesis in the Min/+ mouse colon.
Topics: Adenoma; Adenomatous Polyposis Coli; Alleles; Animals; Azoxymethane; beta Catenin; Carcinogens; Cell Division; Cocarcinogenesis; Colonic Neoplasms; Cytoskeletal Proteins; Female; Genes, APC; Genetic Predisposition to Disease; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Precancerous Conditions; Trans-Activators | 2001 |
Aberrant transforming growth factor-beta signaling in azoxymethane-induced mouse colon tumors.
Topics: Adenoma; Animals; Azoxymethane; Carcinogens; Cell Cycle Proteins; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p15; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Inbred A; Mice, Inbred AKR; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Smad3 Protein; Smad7 Protein; Trans-Activators; Transcription Factors; Transforming Growth Factor beta; Tumor Suppressor Proteins | 2001 |
Chemoprevention of azoxymethane-induced rat colon carcinogenesis by dietary capsaicin and rotenone.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Capsaicin; Carcinogens; Colonic Neoplasms; Diet; Dose-Response Relationship, Drug; Glutathione Transferase; Insecticides; Male; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Inbred F344; Rotenone | 2001 |
Effect of bisacodyl and cascara on growth of aberrant crypt foci and malignant tumors in the rat colon.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Bisacodyl; Carcinogens; Colon; Colonic Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Precancerous Conditions; Rats; Rats, Wistar; Rhamnus | 2001 |
Comparative study of histopathologic characterization of azoxymethane-induced colon tumors in three inbred rat strains.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Biomarkers, Tumor; Carcinogens; Colorectal Neoplasms; Disease Models, Animal; Female; Fluorescent Antibody Technique, Indirect; Immunoenzyme Techniques; Injections, Subcutaneous; Male; Polymorphism, Genetic; Rats; Rats, Inbred F344; Reproducibility of Results; Species Specificity; Time Factors | 2002 |
Effects of lyophilized black raspberries on azoxymethane-induced colon cancer and 8-hydroxy-2'-deoxyguanosine levels in the Fischer 344 rat.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenocarcinoma; Adenoma; Animals; Anthocyanins; Anticarcinogenic Agents; Azoxymethane; Calcium; Cholesterol; Colonic Neoplasms; Coumaric Acids; Deoxyguanosine; Diet; Ellagic Acid; Freeze Drying; Fruit; Oxidative Stress; Rats; Rats, Inbred F344; Rosaceae; Sitosterols | 2001 |
Enhanced colon carcinogenesis induced by azoxymethane in min mice occurs via a mechanism independent of beta-catenin mutation.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Cytoskeletal Proteins; DNA Primers; Male; Mice; Mice, Inbred C57BL; Mutagenesis; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Trans-Activators | 2002 |
Attenuation by the GABA receptor agonist baclofen of experimental carcinogenesis in rat colon by azoxymethane.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Baclofen; Cell Division; Colon; Colonic Neoplasms; Hyperplasia; Intestinal Mucosa; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
Aberrant crypt foci and microadenoma as markers for colon cancer.
Topics: Adenoma; Animals; Azoxymethane; Cocarcinogenesis; Colonic Neoplasms; Diet; Hot Temperature; Mice; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344 | 1992 |
Enhancement by thyroxine of experimental carcinogenesis induced in rat colon by azoxymethane.
Topics: Adenocarcinoma; Adenoma; Analysis of Variance; Animals; Azoxymethane; Body Weight; Carcinogens; Colonic Neoplasms; Drug Synergism; Intestinal Mucosa; Male; Mitotic Index; Neoplasm Metastasis; Probability; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine | 1992 |
Enhanced induction of colon carcinogenesis by azoxymethane in Wistar rats fed a low-protein diet.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Cell Division; Colon; Colonic Neoplasms; Dietary Proteins; Gastrins; Intestinal Mucosa; Male; Norepinephrine; Rats; Rats, Inbred Strains | 1992 |
Inhibition of azoxymethane-induced experimental colon carcinogenesis in Wistar rats by 6-hydroxydopamine.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinoma in Situ; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains | 1992 |
Inhibition by putrescine of experimental carcinogenesis in rat colon induced by azoxymethane.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Body Weight; Carcinoma in Situ; Cell Transformation, Neoplastic; Colonic Neoplasms; Male; Ornithine Decarboxylase; Putrescine; Rats; Rats, Inbred Strains | 1991 |
Inhibition of experimental colorectal carcinogenesis by dietary N-6 polyunsaturated fats.
Topics: Adenoma; Adipose Tissue; Animals; Arachidonic Acid; Arachidonic Acids; Azoxymethane; Carcinoma; Cell Membrane; Colorectal Neoplasms; Fats, Unsaturated; Fatty Acids; Intestinal Mucosa; Linoleic Acid; Linoleic Acids; Male; Oleic Acid; Oleic Acids; Palmitic Acid; Palmitic Acids; Rats; Rats, Inbred Strains; Stearic Acids; Weight Gain | 1990 |
Enhancement by neurotensin of experimental carcinogenesis induced in rat colon by azoxymethane.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Body Weight; Colonic Neoplasms; Drug Synergism; Gastrins; Male; Neurotensin; Rats; Rats, Inbred Strains | 1990 |
Promotion of colonic microadenoma growth in mice and rats fed cooked sugar or cooked casein and fat.
Topics: Adenoma; Animals; Azoxymethane; Body Weight; Caseins; Colonic Neoplasms; Dietary Carbohydrates; Dietary Fats; Female; Hot Temperature; Mice; Rats; Rats, Inbred F344; Time Factors | 1990 |
Enhancement of azoxymethane-induced colon carcinogenesis in spontaneously hypertensive rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinoma in Situ; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity | 1990 |
Tissue norepinephrine depletion as a mechanism for cysteamine inhibition of colon carcinogenesis induced by azoxymethane in Wistar rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinoma; Cell Division; Colon; Colonic Neoplasms; Cysteamine; Gastrins; Male; Norepinephrine; Rats; Rats, Inbred Strains | 1989 |
An investigation of colon cancer associated with urinary diversion.
Topics: Adenocarcinoma; Adenoma; Anastomosis, Surgical; Animals; Azoxymethane; Colon; Colonic Neoplasms; Male; Mesocolon; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Diversion | 1989 |
Inhibitory effect of dietary p-methoxybenzeneselenol on azoxymethane-induced colon and kidney carcinogenesis in female F344 rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anisoles; Azoxymethane; Colonic Neoplasms; Diet; Female; Kidney Neoplasms; Neoplasms, Multiple Primary; Organoselenium Compounds; Rats; Rats, Inbred F344; Selenium; Wilms Tumor | 1985 |
Interactions of selenium deficiency, vitamin E, polyunsaturated fat, and saturated fat on azoxymethane-induced colon carcinogenesis in male F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Dietary Fats; Dimethylhydrazines; Fatty Acids, Unsaturated; Intestinal Neoplasms; Male; Rats; Rats, Inbred F344; Selenium; Vitamin E | 1986 |
Effect of warfarin on formation and growth of pre-neoplastic lesions in chemically induced colorectal cancer in the rat.
Topics: Adenoma; Animals; Azoxymethane; Colon; Colonic Neoplasms; Disease Models, Animal; Intestinal Mucosa; Male; Microscopy, Electron, Scanning; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred Strains; Rectal Neoplasms; Rectum; Warfarin | 1986 |
Effect of warfarin on cell kinetics, epithelial morphology and tumour incidence in induced colorectal cancer in the rat.
Topics: Adenoma; Animals; Azoxymethane; Cell Cycle; Colon; Colonic Neoplasms; Epithelium; Male; Microscopy, Electron, Scanning; Rats; Rats, Inbred Strains; Rectal Neoplasms; Rectum; Warfarin | 1985 |