azoxymethane has been researched along with Adenocarcinoma in 192 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (7.29) | 18.7374 |
| 1990's | 68 (35.42) | 18.2507 |
| 2000's | 65 (33.85) | 29.6817 |
| 2010's | 40 (20.83) | 24.3611 |
| 2020's | 5 (2.60) | 2.80 |
| Authors | Studies |
|---|---|
| Chilton, BS; Helmer, RA; Kaur, G; Smith, LA | 1 |
| Li, Y; Liu, G; Liu, J; Ma, Y; Pan, Z; She, J; Wei, Q; Xia, H; Zhang, M; Zhang, RX | 1 |
| Biddick, L; Janakiram, NB; Li, Q; Lightfoot, S; Lubet, RA; Madka, V; Miller, MS; Mohammed, A; Rao, CV; Sei, S; Singh, A; Steele, VE; Suen, CS; Zhang, Y | 1 |
| Bars-Cortina, D; Macià, A; Martínez-Bardají, A; Motilva, MJ; Piñol-Felis, C | 1 |
| Kojima, H; Kubota, A; Maeda, H; Miyashita, K; Mutoh, M; Ogasa, S; Sano, T; Tanaka, T; Terasaki, M; Uehara, O | 1 |
| He, JM; Hu, JN; Liang, X | 1 |
| Abba, MC; Blidner, AG; Cagnoni, AJ; Croci, DO; Cutine, AM; Gatto, SG; Giribaldi, ML; Mariño, KV; Morales, RM; Rabinovich, GA; Salatino, M | 1 |
| Esa, NM; Ishak, NIM; Madzuki, IN; Mohamed, S; Mustapha, NM | 1 |
| Ganta, V; Janakiram, NB; Kumar, G; Lightfoot, S; Lubet, R; Madka, V; Mohammed, A; Panneerselvam, J; Pathuri, G; Rao, CV; Steele, VE; Suen, CS; Zhang, Y | 1 |
| Faouzi, M; Fleig, A; Furuya, H; Horgen, FD; Huang, J; Kawabata, KG; Kawamori, T; Monteilh-Zoller, M; Penner, R; Zhang, Z | 1 |
| Agle, KA; Chen, X; Drobyski, WR; Huang, YW; Oshima, K; Pan, P; Wang, LS; Yearsley, MM; Yu, J; Zhang, J | 1 |
| Grill, JI; Herbst, A; Kolligs, FT; Marschall, MK; Neumann, J; Ofner, A; Wolf, E; Zierahn, H | 1 |
| Chen, Z; Gao, J; Geng, T; Liu, K; Song, J; Song, W; Tang, H; Wang, M; Yi, S; Zhou, W | 1 |
| Chu, Y; Gu, J; Huang, E; Li, Y; Liang, Y; Liu, J; Liu, R; Lu, Z; Wang, L; Wang, Z; Yu, H; Zhang, D; Zhang, H | 1 |
| Bissonnette, M; Chen, CT; Chen, NT; Dougherty, U; Hart, J; Lo, LW; Souris, JS; Waller, JV; Zhang, HJ | 1 |
| Drachenberg, C; Heath, J; Peng, Z; Raufman, JP; Xie, G | 1 |
| Brewer, M; Bryant, T; Janakiram, NB; Lightfoot, S; Mohammed, A; Rao, CV; Steele, VE; Zhang, Y | 1 |
| Han, W; Li, W; Wang, H; Zhao, X | 1 |
| Hosono, A; Seki, T; Takai, S; Yamaguchi, M | 1 |
| Chen, Y; Duan, RD; Ekblad, E; Hertervig, E; Min, Y; Nilsson, Å; Voss, U; Wu, Y; Xu, SC; Yang, L; Zhang, P | 1 |
| Chen, T; Clinton, SK; Liu, Z; Pan, Z; Riedl, KM; Schwartz, SJ; Shi, N; Wang, Y; Zhang, X | 1 |
| Brophy, ML; Cai, X; Chang, B; Chen, H; Chen, Y; Dong, Y; Hahn, S; Liu, X; Ma, JX; McManus, J; Pasula, S; Rahman, R; Song, H; Tessneer, KL; Wu, H; Xia, L | 1 |
| Deng, Z; Egilmez, NK; Guo, H; Haribabu, B; Miller, D; Mu, J; Norris, J; Tseng, M; Wang, Q; Wattenberg, B; Yan, J; Zhang, HG; Zhang, L; Zhuang, X | 1 |
| Han, SB; Hong, JT; Kim, EC; Park, KR; Yoon, DY; Yun, HM | 1 |
| Biffoni, M; Bignami, M; Boirivant, M; De Luca, G; Di Carlo, E; Di Meo, S; Grasso, F; Pasquini, L; Rossi, S | 1 |
| Chien, SP; Liu, CT; Liu, MY; Periasamy, S; Wu, WH | 1 |
| Almer, S; Bergström, Å; Blaas, L; Büller, NV; Englert, B; Fredlund, E; Frings, O; Gerling, M; Joost, S; Kirn, LM; Kühl, AA; Kuiper, RV; Toftgård, R; van den Brink, GR; Wielenga, MC | 1 |
| Barton, JK; Welge, WA | 1 |
| Do, SG; Im, SA; Kim, HS; Kim, JW; Lee, CK; Park, CS; Park, YI; Shin, E | 1 |
| Ahn, J; Assefnia, S; Bong, YS; Bueno De Mesquita, PJ; Burt, RW; Byers, SW; Neklason, DW; Tuohy, T | 1 |
| Ahmad, J; El-Shemi, AG; Idris, S; Kensara, OA; Mohamed, AM; Refaat, B | 1 |
| Curini, M; Epifano, F; Genovese, S; Ishigamori-Suzuki, R; Kim, M; Miyamoto, S; Sugie, S; Tanaka, T; Yasui, Y | 1 |
| Oyama, T; Rahman, KM; Tanaka, M; Tanaka, T; Yasui, Y | 1 |
| Chan, JY; Cheung, WK; Hao, X; Huang, MT; Khor, TO; Kong, AN; Liu, Y; Prawan, A; Reddy, BS; Yang, CS; Yu, S | 1 |
| Bielecki, A; Bird, RP; Caldwell, D; Cooke, GM; Curran, I; Kapal, K; Lok, E; Mehta, R; Raju, J; Taylor, M | 1 |
| Hao, X; Ju, J; Lambert, JD; Lee, MJ; Lu, G; Newmark, HL; Xiao, H; Yang, CS | 1 |
| Chen, J; Huang, XF | 1 |
| Keeler, V; Laferté, S; Lim, HJ; Lining, LA; Torlakovic, EE; Wang, C | 1 |
| Frank, JA; Hennings, LJ; Prior, RL; Simmen, FA; Wu, X; Xiao, R | 1 |
| Chapkin, RS; Davidson, LA; Ivanov, I; Lupton, JR; Shah, MS; Wang, N | 1 |
| Guruswamy, S; Kopelovich, L; Patlolla, JM; Rao, CV; Steele, VE; Swamy, MV | 1 |
| Koketsu, M; Oyama, T; Sugie, S; Tanaka, T; Watanabe, K; Yasui, Y | 1 |
| Alexander, A; Fraser, A; Haines, SR; Rosengren, RJ; Scandlyn, MJ; Somers-Edgar, TJ; Stuart, EC | 1 |
| Chan, KM; Cho, CH; Li, H; Li, ZJ; Sung, JJ; Wang, M; Wong, CC; Wu, WK; Ye, CG; Yu, L | 1 |
| Cardone, M; Dai, RM; Gyulai, Z; Haines, D; Jones, Y; Ma, W; Marincola, FM; O'hUigin, C; Salcedo, R; Trinchieri, G; Wang, E; Worschech, A | 1 |
| Imai, T; Masuda, S; Mutoh, M; Nakano, K; Sugimura, T; Takahashi, M; Takasu, S; Teraoka, N; Ueno, T; Wakabayashi, K | 1 |
| Bean, E; Currey, N; Dahlstrom, JE; Daniel, JJ; Gupta, R; Kohonen-Corish, MR; Mladenova, D; Musgrove, EA; Pickford, R | 1 |
| Byeon, JS; Do, EJ; Kim, IW; Kim, JH; Kim, K; Kim, KJ; Kim, MJ; Kwon, IC; Moon, DH; Myung, SJ; Park, K; Ryu, JH; Yang, DH; Yang, SK; Ye, BD; Yoon, SM | 1 |
| Hosokawa, M; Mikami, N; Miyashita, K; Tanaka, T; Yasui, Y | 1 |
| DeCastro, A; Janakiram, NB; Lee, HJ; Paul, S; Rao, CV; Reddy, BS; Simi, B; Smolarek, AK; So, JY; Steele, V; Suh, N; Wang, CX | 1 |
| Akira, S; Hara, S; Ishii, T; Ishikawa, Y; Kamei, D; Murakami, M; Sasaki, Y; Uematsu, S | 1 |
| Antonacopoulou, AG; Bravou, V; Episkopou, V; Kalofonos, HP; Panoutsopoulos, AA; Sharma, V; Tanaka, S | 1 |
| Clarke, M; Das, S; Huels, D; Jamieson, T; Jung, A; Neumann, J; Nibbs, RJ; Olson, MF; Samuel, MS; Sansom, OJ; Steele, CW | 1 |
| Hashimoto, T; Hata, K; Kuramoto, T; Niwa, Y; Serikawa, T; Tanaka, T; Yoshimi, K | 1 |
| Koliaraki, V; Kollias, G; Roulis, M | 1 |
| Hara, A; Hatano, Y; Hirata, A; Hirose, Y; Kuno, T; Masuda, S; Mori, H; Tanaka, T; Terasaki, M; Tomita, H | 1 |
| Aadland, E; Fagerhol, MK; Kristinsson, J; Nygaard, K; Sundseth, A | 1 |
| Biggeri, A; Caderni, G; Clune, Y; Collins, KJ; Dolara, P; Femia, AP; Giannini, A; Luceri, C; Paglierani, M; Salvadori, M | 1 |
| Achenie, LE; Cui, H; Dong, M; Garg, S; Guda, K; Nambiar, PR; Rosenberg, DW | 1 |
| Bennink, MR; Hangen, L | 1 |
| Kawamori, T; Sugimura, T; Uchiya, N; Wakabayashi, K | 1 |
| Fujihara, H; Kamada, N; Kusuoka, O; Masutani, M; Nakagama, H; Nakamoto, K; Nozaki, T; Sugimura, T; Suzuki, H; Tsutsumi, M; Watanabe, M | 1 |
| Beck, F; Bonhomme, C; Chawengsaksophak, K; Chenard, MP; Domon-Dell, C; Duluc, I; Freund, JN; Kedinger, M; Martin, E | 1 |
| Akedo, H; Baba, M; Higashino, K; Iishi, H; Mukai, M; Tatsuta, M; Yano, H | 1 |
| Kohno, H; Mori, H; Sugie, S; Suzuki, R; Tanaka, T; Yamada, Y | 1 |
| Katayama, M; Kondo, K; Nozawa, H; Sonobe, H; Tajima, O; Wakabayashi, K; Yoshida, A | 1 |
| Bonne, A; Fenger, C; Kobaek-Larsen, M; Kristiansen, K; Ritskes-Hoitinga, M; Sørensen, NM; van Zutphen, B | 1 |
| Iwasaki, Y; Kameue, C; Koyama, H; Nakayama, K; Tsukahara, T; Ushida, K; Yamada, K | 1 |
| Baba, M; Higashino, K; Iishi, H; Ishiguro, S; Ishihara, R; Kobayashi, S; Mukai, M; Murakami-Murofushi, K; Tatsuta, M; Uedo, N | 1 |
| Hara, A; Hata, K; Hirose, Y; Kuno, T; Mori, H; Qiang, SH; Yamada, Y | 1 |
| Hosokawa, M; Kohno, H; Miyashita, K; Suzuki, R; Tanaka, T; Yasui, Y | 1 |
| Kohno, H; Sugie, S; Suzuki, R; Tanaka, T | 2 |
| Kawamori, T; Kitamura, T; Maruyama, T; Narumiya, S; Sugimura, T; Uchiya, N; Wakabayashi, K; Watanabe, K | 1 |
| Baba, M; Higashino, K; Iishi, H; Ishiguro, S; Ishihara, R; Mukai, M; Tatsuta, M; Uedo, N | 1 |
| Aviello, G; Borrelli, F; Capasso, F; Capasso, R; Di Carlo, G; Izzo, AA; Mascolo, N | 1 |
| Kohno, H; Nakagama, H; Sugie, S; Suzuki, R; Tanaka, T | 1 |
| Amann, V; Bissahoyo, A; Godfrey, VL; Hanlon, K; Hicks, D; Pearsall, RS; Threadgill, DW | 1 |
| Drenth, JP; Laverman, P; Nagengast, FM; Oyen, WJ; van Kouwen, MC; van Krieken, JH | 1 |
| Costa, RH; Davidson, NO; Wang, IC; Yoder, HM; Yoshida, Y | 1 |
| Alain, T; Beck, PL; Endersby, R; Forsyth, PA; Johnston, RN; Lee, PW; Muruve, DA; Urbanski, SJ; Wong, JF | 1 |
| Kikuchi, H; Kudo, H; Murakami, S; Sakamoto, S; Sassa, S; Suzuki, S | 1 |
| Fox, JG; Nagamine, CM; Rogers, AB; Schauer, DB | 1 |
| Doi, K; Fukushima, S; Hagihara, A; Wanibuchi, H; Wei, M; Yunoki, T | 1 |
| Albert, PS; Barrett, KG; Bennink, MR; Bobe, G; Colburn, NH; Lanza, E; Mentor-Marcel, RA; Saffiotti, U; Young, MR | 1 |
| Mori, H; Nicolais, M; Reddy, BS | 1 |
| Maeura, Y; Reddy, BS | 1 |
| Alabaster, O; Belinsky, SA; Shivapurkar, N; Tang, Z; Wolf, DC | 1 |
| Baba, M; Iishi, H; Nakaizumi, A; Tatsuta, M; Uehara, H; Yano, H | 1 |
| Barzilai, M; Cohen, I; Reshef, R; Rotter, V; Shasha, SM; Shkolnik, T; Tendler, Y | 1 |
| Bird, RP | 1 |
| Baba, M; Iishi, H; Nakaizumi, A; Tatsuta, M; Uehara, H; Yamamoto, R | 1 |
| Baba, M; Iishi, H; Iseki, K; Nakaizumi, A; Tatsuta, M; Uehara, H | 1 |
| Fujimaki, M; Kobashi, K; Murai, K; Ohkami, H; Shimizu, T; Tazawa, K; Yamashita, I | 1 |
| Kelloff, G; Rao, CV; Reddy, BS; Rivenson, A; Simi, B; Steele, V; Zang, E | 1 |
| Cosenza, V; D'Argenio, G; D'Armiento, FP; De Ritis, F; Delle Cave, M; Iovino, P; Mazzacca, G; Sorrentini, I | 1 |
| Conney, AH; Huang, MT; Lou, YR; Ma, W; Newmark, HL; Reuhl, KR | 1 |
| Baba, M; Iishi, H; Nakaizumi, A; Tatsuta, M; Uehara, H | 1 |
| Cheyer, C; O'Riordan, MA; Pretlow, TP | 1 |
| Biggeri, A; Caderni, G; Dolara, P; Giannini, A; Luceri, C; Spagnesi, MT | 1 |
| Alabaster, O; Ferreira, A; Garett, C; Nasim, S; Shivapurkar, N; Tang, Z | 1 |
| Bird, RP; Stopera, SA | 1 |
| Kelloff, G; Rao, CV; Reddy, BS; Rivenson, A | 1 |
| Kojima, T; Mori, H; Suzui, M; Tanaka, T | 1 |
| Ghose, T; Reddy, BS; Rijhsinghani, K | 1 |
| Bruce, WR; Gallinger, S; Hay, K; Medline, A; Shpitz, B; Stern, HS; Vivona, AA; Ward, MA | 1 |
| Katiwalla, M; Kelloff, GJ; Rao, CV; Reddy, BS; Rivenson, A | 1 |
| Rao, CV; Reddy, BS; Rivenson, A; Simi, B | 1 |
| Gustafson-Svärd, C; Hallböök, O; Lilja, I; Sjödahl, R | 1 |
| Barnes, LH; Kelloff, GV; Lubet, RA; Pereira, MA; Steele, VE | 1 |
| Aukema, HM; Chang, WC; Chapkin, RS; Jiang, YH; Jolly, CA; Lupton, JR | 1 |
| Aquino, B; Bissonnette, M; Brasitus, TA; Khare, S; Niedziela, S; Sitrin, M; Wali, RK | 1 |
| Akedo, H; Baba, M; Iishi, H; Nakaizumi, A; Tatsuta, M; Uehara, H | 1 |
| Alabaster, O; Frost, A; Shivapurkar, N; Tang, ZC | 1 |
| Kelloff, GJ; Lubet, R; Rao, CV; Reddy, BS; Samaha, H; Steele, VE; Wang, CX | 1 |
| El-Bayoumy, K; Pittman, B; Rao, CV; Reddy, BS; Rivenson, A; Upadhyaya, P | 1 |
| Fukuda, K; Ohata, T; Sugimura, T; Takahashi, M; Wakabayashi, K | 1 |
| Kelloff, GJ; Rao, CV; Reddy, BS; Samaha, HS; Steele, V | 1 |
| Hirose, Y; Kawabata, K; Mori, H; Suzui, M; Tanaka, T; Yoshimi, N | 1 |
| Asamoto, M; Baba-Toriyama, H; Kakizoe, T; Kim, DJ; Krutovskikh, V; Masuda, M; Moore, MA; Nakamura, J; Nishino, H; Ota, T; Sekine, K; Sugimoto, H; Takasuka, N; Tsuda, H; Watanabe, E | 1 |
| Kelloff, G; Lubet, R; Rao, CV; Reddy, BS; Simi, B; Steele, V; Wang, CX | 1 |
| Akedo, H; Baba, M; Funai, H; Iishi, H; Ishiguro, S; Kitagawa, I; Nakaizumi, A; Shinkai, K; Tatsuta, M; Uehara, H | 1 |
| Ganthavorn, C; Hughes, JS; Wilson-Sanders, S | 1 |
| Fukuda, K; Sugimura, T; Takahashi, M; Wakabayashi, K | 1 |
| Kajiura, K; Ohkusa, T; Okayasu, I | 1 |
| Brockman, J; DuBois, RN; Gupta, R; Krakow, SL; Lazar, MA; Reddy, BS | 1 |
| Chang, WL; Chapkin, RS; Lupton, JR | 1 |
| Alink, GM; Hollanders, VM; Koeman, JH; Rijnkels, JM; Woutersen, RA | 1 |
| Bak, AW; Calignano, A; Cirino, G; Del Soldato, P; Li, P; McKnight, W; Wallace, JL | 1 |
| Bazzicalupo, M; Briani, C; Caderni, G; De Filippo, C; Dolara, P; Fazi, M; Giannini, A | 1 |
| Kelloff, GJ; Kramer, PM; Lubet, RA; Pereira, MA; Steele, VE; Zheng, Y | 1 |
| Di Betta, E; Fontana, MG; Ghirardi, M; Nascimbeni, R; Salerni, B; Villanacci, V | 1 |
| Esumi, H; Fukushima, S; Otori, K; Sugiyama, K | 1 |
| Kawamori, T; Kelloff, GJ; Lubet, RA; Rao, CV; Reddy, BS; Steele, VE | 1 |
| Hara, A; Honjo, S; Kakumoto, M; Kawabata, K; Makita, H; Mori, H; Tanaka, T; Tsuda, H; Ushida, J | 1 |
| Kawamori, T; Kelloff, G; Lubet, R; Rao, CV; Reddy, BS; Steele, V | 1 |
| Ikeda, M; Matsumoto, K; Moriyama, R; Morotomi, M; Sakaitani, Y; Satou, M; Takagi, A; Takahashi, T; Uchida, K; Watanabe, N | 1 |
| Alvarez, M; Bartolí, R; Cabré, E; Castellà, E; Fernández-Bañares, F; Gassull, MA; Mañé, J; Navarro, E; Pastor, C | 1 |
| Kelloff, GJ; Kramer, PM; Li, H; Lubet, RA; Pereira, MA; Steele, VE | 1 |
| Hirose, Y; Kelloff, GJ; Lubet, RA; Rao, CV; Reddy, BS; Steele, VE | 1 |
| Han, BS; Iigo, M; Kuhara, T; Moore, MA; Sekine, K; Takasuka, N; Tsuda, H; Ushida, Y | 1 |
| Kral, JG; Scholes, J; Stein, DE; Weber, RV | 1 |
| Baba, M; Iishi, H; Nakaizumi, A; Sakai, N; Tatsuta, M; Uehara, H; Yano, H | 1 |
| Kawamori, T; Mutoh, M; Sugimura, T; Takahashi, M; Wakabayashi, K | 1 |
| Dong, M; Guda, K; Papanikolaou, A; Rosenberg, DW; Wang, QS | 1 |
| Battey, JF; Benya, RV; Carroll, RE; Matkowskyj, KA; Tretiakova, MS | 1 |
| Nambiar, PR; Papanikolaou, A; Rosenberg, DW; Wang, QS | 1 |
| Azuma, Y; Kagami, S; Kohno, H; Murakami, M; Ogawa, H; Shimada, R; Sumida, T; Tanaka, T | 1 |
| Caderni, G; De Filippo, C; Dolara, P; Gambacciani, L; Giannini, A; Luceri, C; Salvadori, M | 1 |
| Cohen, LA; Cooma, I; Hirose, Y; Rao, CV; Reddy, BS; Simi, B | 1 |
| Le Leu, RK; McIntosh, GH; Young, GP | 1 |
| Iijima, H; Kobayashi, H; Matsunaga, K | 1 |
| Badger, TM; Hakkak, R; Johnston, JM; Korourian, S; Ronis, MJ | 1 |
| Katayama, S; Kudoh, S; Matsuda, S | 1 |
| Imai, H; Kawamori, T; Nakagama, H; Ochiai, M; Sugimura, T; Ubagai, T | 1 |
| Kohno, H; Takashima, S; Tanaka, T; Yoshitani, SI | 1 |
| Boggio, M; Borrelli, F; Capasso, F; Izzo, AA; Mascolo, N; Massa, B; Mereto, E; Orsi, P; Sini, D | 1 |
| Carroll, RJ; Chang, WC; Chapkin, RS; Davidson, LA; Hong, MY; Lupton, JR; Morris, JS; Turner, ND; Wang, N | 1 |
| Akedo, H; Baba, M; Iishi, H; Mukai, M; Murata, K; Tatsuta, A; Yano, H | 1 |
| den, BM; Diederichsen, A; Fenger, C; Hansen, K; Kobaek-Larsen, M; Nissen, I; Ritskes-Hoitinga, M; Thorup, I; Vach, W | 1 |
| Frankel, WL; Gallaher, DD; Gupta, A; Habib, SG; Harris, GK; Kresty, LA; LaPerle, K; Nines, RG; Schwartz, SJ; Stoner, GD | 1 |
| Moriwaki, H; Nakagama, H; Okuno, M; Suzui, M; Tanaka, T | 1 |
| Aizu, W; Giardina, C; Guda, K; Nambiar, PR; Raja, R; Rosenberg, DW | 1 |
| Ward, JM | 1 |
| Bauer, FL; Malt, RA; Ross, JS; Watkins, JB; Williamson, RC | 1 |
| Brown, CA | 1 |
| Campbell, RL; Lin, YN; Nigro, ND; Singh, DV | 1 |
| Baba, M; Iishi, H; Taniguchi, H; Tatsuta, M | 5 |
| Bird, RP; Murphy, LC; Stopera, SA | 1 |
| Baba, M; Iishi, H; Taniguchi, H; Tatsuta, M; Yamamoto, R | 1 |
| Baba, M; Iishi, H; Okuda, S; Taniguchi, H; Tatsuta, M | 3 |
| Clinton, SK; Imrey, PB; Mangian, HJ; Nandkumar, S; Visek, WJ | 1 |
| Burill, C; Reddy, BS; Rigotty, J | 1 |
| Ballet, F; Delelo, R; Herve, JP; Nordlinger, B; Panis, Y; Puts, JP | 1 |
| Gershbein, LL | 1 |
| Baba, M; Ichii, M; Iishi, H; Nakaizumi, A; Taniguchi, H; Tatsuta, M; Uehara, H | 1 |
| Dornschneider, G; Eibl-Eibesfeldt, B; Hamilton, SR; Harnisch, E; Izbicki, JR; Schweiberer, L; Wambach, G; Wilker, DK | 1 |
| Baba, M; Iishi, H; Taniguchi, H; Tasuta, M | 1 |
| Flick, JA; Hamilton, SR; Perman, JA; Rosales, FJ | 1 |
| Donegan, WL; Kusama, K; Samter, TG | 1 |
| El-Bayoumy, K; Reddy, BS; Tanaka, T | 1 |
| Baba, M; Iishi, H; Taniguchi, H; Tatsuta, M; Yamamura, H | 1 |
| Bird, RP; Goettler, DM; Rao, AV | 1 |
| Reddy, BS; Tanaka, T | 1 |
| Maruyama, H; Reddy, BS | 1 |
| Choi, CI; Numoto, S; Reddy, BS | 1 |
2 review(s) available for azoxymethane and Adenocarcinoma
| Article | Year |
|---|---|
The signal pathways in azoxymethane-induced colon cancer and preventive implications.
Topics: Adenocarcinoma; Adenoma; Adiponectin; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogens; Colonic Neoplasms; Cytochrome P-450 CYP2E1; Diet; DNA Damage; Genes, ras; Humans; MAP Kinase Signaling System; Methylazoxymethanol Acetate; Mice; Mice, Knockout; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Transforming Growth Factor beta; Transforming Growth Factor beta2 | 2009 |
Role of aberrant crypt foci in understanding the pathogenesis of colon cancer.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Cholic Acid; Cholic Acids; Colon; Colonic Neoplasms; Dietary Fats; Dimethylhydrazines; Genes, ras; Humans; Intestinal Mucosa; Precancerous Conditions | 1995 |
190 other study(ies) available for azoxymethane and Adenocarcinoma
| Article | Year |
|---|---|
Helicase-like transcription factor (Hltf) gene-deletion promotes oxidative phosphorylation (OXPHOS) in colorectal tumors of AOM/DSS-treated mice.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; DNA-Binding Proteins; Gene Deletion; Gene Expression Regulation, Neoplastic; Mice, Inbred C57BL; Mitochondria; Oxidative Phosphorylation; Survival Analysis; Transcription Factors | 2019 |
Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch.
Topics: Adenocarcinoma; Animals; Appendectomy; Azoxymethane; Carcinogens; Cecum; Chronic Disease; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Male; Mice, Inbred C57BL | 2019 |
Intermittent Dosing Regimens of Aspirin and Naproxen Inhibit Azoxymethane-Induced Colon Adenoma Progression to Adenocarcinoma and Invasive Carcinoma.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azoxymethane; Carcinogens; Colonic Neoplasms; Dose-Response Relationship, Drug; Male; Naproxen; Neoplasm Invasiveness; Rats; Rats, Wistar | 2019 |
Consumption evaluation of one apple flesh a day in the initial phases prior to adenoma/adenocarcinoma in an azoxymethane rat colon carcinogenesis model.
Topics: Adenocarcinoma; Animals; Anthocyanins; Azoxymethane; Carcinogenesis; Colonic Neoplasms; Flavonoids; Fruit; Galactosides; Humans; Male; Malus; Plant Extracts; Polyphenols; Rats; Rats, Wistar | 2020 |
Alteration of fecal microbiota by fucoxanthin results in prevention of colorectal cancer in AOM/DSS mice.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colitis-Associated Neoplasms; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Drug Screening Assays, Antitumor; Feces; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Male; Mice; Xanthophylls | 2021 |
An Optimized Protocol of Azoxymethane-Dextran Sodium Sulfate Induced Colorectal Tumor Model in Mice.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Body Weight; Carcinogenesis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Male; Mice, Inbred C57BL | 2019 |
Galectin-1 fosters an immunosuppressive microenvironment in colorectal cancer by reprogramming CD8
Topics: Adenocarcinoma; Animals; Atlases as Topic; Azoxymethane; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Colitis; Colorectal Neoplasms; Computational Biology; Dextran Sulfate; Disease Models, Animal; Galectin 1; Gene Expression Regulation, Neoplastic; Humans; Interleukin-2 Receptor beta Subunit; Mice; Mice, Knockout; Programmed Cell Death 1 Receptor; Signal Transduction; Survival Analysis; T-Lymphocytes, Regulatory; Tumor Burden | 2021 |
Limonin modulated immune and inflammatory responses to suppress colorectal adenocarcinoma in mice model.
Topics: Adenocarcinoma; Animals; Antioxidants; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Limonins; Male; Mice; Mice, Inbred BALB C; Oxidative Stress | 2021 |
Proton Pump Inhibitor Omeprazole Suppresses Carcinogen-induced Colonic Adenoma Progression to Adenocarcinoma in F344 Rat.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Omeprazole; Proton Pump Inhibitors; Rats; Rats, Inbred F344 | 2021 |
Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice.
Topics: Acetates; Adenocarcinoma; Animals; Azoxymethane; Calcium; Cell Proliferation; Cells, Cultured; Colonic Neoplasms; Diterpenes; HT29 Cells; Humans; Intestinal Absorption; Magnesium Deficiency; Male; Mice; Mice, Inbred C57BL; TRPM Cation Channels | 2017 |
Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colitis; Colonic Neoplasms; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dextran Sulfate; Disease Progression; Epigenesis, Genetic; Histone Deacetylases; Homeostasis; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Neutrophils; Receptors, G-Protein-Coupled | 2018 |
Dro1/Ccdc80 inactivation promotes AOM/DSS-induced colorectal carcinogenesis and aggravates colitis by DSS in mice.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Epithelial-Mesenchymal Transition; Extracellular Matrix Proteins; Genes, Tumor Suppressor; Glycoproteins; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout | 2018 |
Deleting MyD88 signaling in myeloid cells promotes development of adenocarcinomas of the colon.
Topics: Adenocarcinoma; Animals; Azoxymethane; beta Catenin; Colonic Neoplasms; Cytokines; Dextran Sulfate; DNA Damage; Gene Knockout Techniques; Humans; Mice; Mutation; Myeloid Cells; Myeloid Differentiation Factor 88; Signal Transduction; Tumor Burden | 2018 |
Deceleration of glycometabolism impedes IgG-producing B-cell-mediated tumor elimination by targeting SATB1.
Topics: Adenocarcinoma; Aged; Animals; Azoxymethane; B-Lymphocytes; Cells, Cultured; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Glucose; Humans; Immunoglobulin G; Lung Neoplasms; Male; Matrix Attachment Region Binding Proteins; Mice; Mice, Inbred C57BL; Neoplasms; Promoter Regions, Genetic; RNA, Small Interfering; STAT6 Transcription Factor | 2019 |
A novel mouse model of sporadic colon cancer induced by combination of conditional Apc genes and chemical carcinogen in the absence of Cre recombinase.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colonic Neoplasms; Disease Models, Animal; Genes, APC; Integrases; Mice; Mice, Inbred C57BL | 2019 |
Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis.
Topics: Adenocarcinoma; Animals; Azoxymethane; Bethanechol; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; ErbB Receptors; Gene Expression; Hypoxia-Inducible Factor 1, alpha Subunit; Intestinal Mucosa; Male; Matrix Metalloproteinase 10; Matrix Metalloproteinase 13; Matrix Metalloproteinase 7; Mice; Muscarinic Agonists; Proto-Oncogene Proteins c-myc; Receptor, Muscarinic M3; RNA, Messenger; Signal Transduction; Tumor Burden | 2013 |
Chemopreventive efficacy of raloxifene, bexarotene, and their combination on the progression of chemically induced colon adenomas to adenocarcinomas in rats.
Topics: Adenocarcinoma; Adenoma; Adult; Aged; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Bexarotene; Biomarkers, Tumor; Blotting, Western; Colonic Neoplasms; Drug Therapy, Combination; Estrogen Antagonists; Estrogen Receptor beta; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Neoplasm Grading; Raloxifene Hydrochloride; Rats; Rats, Inbred F344; Real-Time Polymerase Chain Reaction; Retinoid X Receptors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrahydronaphthalenes; Tissue Array Analysis; Tumor Cells, Cultured | 2013 |
[Changes of expression of miR-155 in colitis-associated colonic carcinogenesis].
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Cocarcinogenesis; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Gene Expression Profiling; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Precancerous Conditions; Up-Regulation | 2014 |
Bovine milk-derived α-lactalbumin inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sodium sulfate-treated mice.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Carcinogenesis; Cattle; Colon; Colonic Neoplasms; Dextran Sulfate; Dietary Supplements; Dinoprostone; Inflammation; Interleukin-1beta; Lactalbumin; Male; Mice; Mice, Inbred C57BL; Milk; Occult Blood; Organ Size; Tumor Necrosis Factor-alpha | 2014 |
Enhanced colonic tumorigenesis in alkaline sphingomyelinase (NPP7) knockout mice.
Topics: Adenocarcinoma; Animals; Azoxymethane; beta Catenin; Carrier Proteins; Colonic Neoplasms; Dextran Sulfate; Intestinal Mucosa; Mice; Mice, Knockout; Sphingolipids; Sphingomyelin Phosphodiesterase | 2015 |
Strawberry phytochemicals inhibit azoxymethane/dextran sodium sulfate-induced colorectal carcinogenesis in Crj: CD-1 mice.
Topics: Adenocarcinoma; Adenoma; Animals; Anthocyanins; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Ellagic Acid; Flavonols; Fragaria; Fruit; Functional Food; Inflammation Mediators; Male; Mice, Inbred ICR; Phytochemicals; Phytotherapy | 2015 |
Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Adenocarcinoma; Animals; Azoxymethane; Binding Sites; Colitis; Colon; Colonic Neoplasms; Dishevelled Proteins; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Mice; Mice, Knockout; Phosphoproteins; Primary Cell Culture; Protein Binding; Protein Interaction Domains and Motifs; Protein Stability; RNA, Small Interfering; Sodium Dodecyl Sulfate; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2015 |
Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis.
Topics: Adenocarcinoma; Animals; Azoxymethane; Bacteroides fragilis; Blotting, Western; Carcinogenesis; Carcinogens; Cell Line, Tumor; Cell Proliferation; Chemokine CCL20; Colitis; Colonic Neoplasms; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Enterobacteriaceae; Exosomes; Immunohistochemistry; In Situ Hybridization, Fluorescence; Inflammation; Intestinal Mucosa; Lysophospholipids; Mice; Myeloid Differentiation Factor 88; Nanoparticles; Neoplasm Transplantation; Reverse Transcriptase Polymerase Chain Reaction; Sphingosine; Th17 Cells | 2015 |
IL-32α suppresses colorectal cancer development via TNFR1-mediated death signaling.
Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; Enzyme Activation; Humans; Inflammation; Interleukins; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Transgenic; Neoplasm Proteins; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins; Signal Transduction | 2015 |
The MUTYH base excision repair gene protects against inflammation-associated colorectal carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Bone Marrow Cells; CD8-Positive T-Lymphocytes; Cell Transformation, Neoplastic; Colitis; Colon; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Disease Models, Animal; DNA Glycosylases; Forkhead Transcription Factors; Guanine; Inflammation Mediators; Mice, Knockout; T-Lymphocytes, Regulatory; Time Factors | 2015 |
Dietary Ziziphus jujuba Fruit Influence on Aberrant Crypt Formation and Blood Cells in Colitis-Associated Colorectal Cancer in Mice.
Topics: Aberrant Crypt Foci; Adenocarcinoma; Animals; Azoxymethane; Carcinogenesis; Chemoprevention; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Diet; Dietary Supplements; Disease Progression; Hyperplasia; Leukocyte Count; Leukocytes; Male; Mice; Mice, Inbred C57BL; Plant Preparations; Ziziphus | 2015 |
Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth.
Topics: Adenocarcinoma; Animals; Azoxymethane; Bone Morphogenetic Proteins; Carcinogenesis; Cell Proliferation; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Integrases; Mice, Inbred C57BL; Recombination, Genetic; Signal Transduction; Stromal Cells; Transcription, Genetic; Tumor Burden | 2016 |
In vivo endoscopic Doppler optical coherence tomography imaging of the colon.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colonic Neoplasms; Disease Models, Animal; Endosonography; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Sensitivity and Specificity; Tomography, Optical Coherence | 2017 |
Prevention of azoxymethane/dextran sodium sulfate-induced mouse colon carcinogenesis by processed Aloe vera gel.
Topics: Adenocarcinoma; Aloe; Animals; Azoxymethane; Carcinogenesis; CDX2 Transcription Factor; Cell Cycle; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gels; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; NF-kappa B; Plant Extracts; Tumor Suppressor Proteins | 2016 |
A role for the vitamin D pathway in non-intestinal lesions in genetic and carcinogen models of colorectal cancer and in familial adenomatous polyposis.
Topics: Adenocarcinoma; Adenomatous Polyposis Coli; Animals; Azoxymethane; beta Catenin; Cell Transformation, Neoplastic; Colorectal Neoplasms; Disease Models, Animal; Disease Progression; Gardner Syndrome; Genes, APC; Genetic Predisposition to Disease; Mice, Inbred C57BL; Mice, Knockout; Mutation; Phenotype; Polymorphism, Single Nucleotide; Receptors, Calcitriol; Risk Factors; Time Factors; Vitamin D; Wnt Signaling Pathway | 2016 |
Activins and their related proteins in colon carcinogenesis: insights from early and advanced azoxymethane rat models of colon cancer.
Topics: Activins; Adenocarcinoma; Animals; Azoxymethane; Biomarkers, Tumor; Carcinogenesis; Colonic Neoplasms; Disease Progression; Follistatin; Gene Expression; Male; Precancerous Conditions; Rats, Wistar | 2016 |
A novel prodrug of 4'-geranyloxy-ferulic acid suppresses colitis-related colon carcinogenesis in mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenocarcinoma; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Chemoprevention; Colitis; Colonic Neoplasms; Coumaric Acids; Deoxyguanosine; Dextran Sulfate; Dipeptides; Disease Models, Animal; Heme Oxygenase (Decyclizing); Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; Oxidative Stress; Prodrugs | 2008 |
Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Biomarkers, Tumor; Colon; Colonic Neoplasms; Dextran Sulfate; Dose-Response Relationship, Drug; Drinking; Immunohistochemistry; Injections, Intraperitoneal; Interleukin-1beta; Intestinal Mucosa; Male; Melatonin; Mitotic Index; NF-kappa B; Rats; Rats, Inbred F344; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha | 2009 |
Increased susceptibility of Nrf2 knockout mice to colitis-associated colorectal cancer.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Cyclooxygenase 2; Cytoprotection; Dextran Sulfate; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2 | 2008 |
Soy isoflavones modulate azoxymethane-induced rat colon carcinogenesis exposed pre- and postnatally and inhibit growth of DLD-1 human colon adenocarcinoma cells by increasing the expression of estrogen receptor-beta.
Topics: Adenocarcinoma; Animals; Animals, Newborn; Azoxymethane; Carcinogens; Cell Line, Tumor; Colonic Neoplasms; Diet; Estrogen Receptor beta; Female; Gene Expression Regulation, Neoplastic; Glycine max; Humans; Isoflavones; Male; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Sprague-Dawley | 2009 |
A gamma-tocopherol-rich mixture of tocopherols inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sulfate sodium-treated mice.
Topics: Adenocarcinoma; Adenoma; Animals; Antioxidants; Apoptosis; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Colon; Colonic Neoplasms; Dextran Sulfate; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; gamma-Tocopherol; Inflammation; Leukotriene B4; Male; Mice; Tyrosine | 2009 |
Cyclophilin C-associated protein (CyCAP) knock-out mice spontaneously develop colonic mucosal hyperplasia and exaggerated tumorigenesis after treatment with carcinogen azoxymethane.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Cell Proliferation; Colon; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Glycoproteins; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Mice, Knockout | 2009 |
Lack of efficacy of blueberry in nutritional prevention of azoxymethane-initiated cancers of rat small intestine and colon.
Topics: Adenocarcinoma; Adenomatous Polyps; Animals; Azoxymethane; Blueberry Plants; C-Peptide; Colonic Neoplasms; Disease Models, Animal; Disease Progression; Duodenal Neoplasms; Female; Incidence; Male; Nutrition Therapy; Rats; Rats, Sprague-Dawley | 2009 |
n-3 Polyunsaturated fatty acids modulate carcinogen-directed non-coding microRNA signatures in rat colon.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Epigenesis, Genetic; Fatty Acids, Unsaturated; Fish Oils; Gene Expression Profiling; Male; MicroRNAs; Pectins; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Inhibition of azoxymethane-induced colorectal cancer by CP-31398, a TP53 modulator, alone or in combination with low doses of celecoxib in male F344 rats.
Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Blotting, Western; Carcinogens; Celecoxib; Cell Proliferation; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Drug Therapy, Combination; Immunoenzyme Techniques; In Situ Nick-End Labeling; Male; Maximum Tolerated Dose; Membrane Proteins; Pyrazoles; Pyrimidines; Rats; Rats, Inbred F344; Sulfonamides; Tumor Suppressor Protein p53 | 2009 |
Dietary tricin suppresses inflammation-related colon carcinogenesis in male Crj: CD-1 mice.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Blotting, Western; Carcinogens; Colonic Neoplasms; Diet; Flavonoids; Inflammation; Male; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
Deer velvet supplementation decreases the grade and metastasis of azoxymethane-induced colon cancer in the male rat.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Azoxymethane; Colonic Neoplasms; Disease Models, Animal; Male; Neoplasm Metastasis; Rats; Rats, Wistar; Skin; Tissue Extracts | 2010 |
2,3',4,4',5'-Pentamethoxy-trans-stilbene, a resveratrol derivative, inhibits colitis-associated colorectal carcinogenesis in mice.
Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Cell Line, Tumor; Cell Proliferation; Colitis; Colonic Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred BALB C; Stilbenes | 2010 |
MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18.
Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; beta Catenin; Cell Proliferation; Colon; Colonic Neoplasms; Colonic Polyps; Cyclooxygenase 2; Dextran Sulfate; DNA Repair Enzymes; Epithelial Cells; Gene Expression; Gene Expression Profiling; Genetic Predisposition to Disease; Inflammatory Bowel Diseases; Interleukin-18; Interleukin-18 Receptor alpha Subunit; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Myeloid Differentiation Factor 88; Phosphorylation; Receptors, Interleukin-1 Type I; Signal Transduction; Specific Pathogen-Free Organisms; STAT3 Transcription Factor | 2010 |
High susceptibility to azoxymethane-induced colorectal carcinogenesis in obese KK-Ay mice.
Topics: Aberrant Crypt Foci; Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Disease Models, Animal; Disease Susceptibility; Incidence; Mice; Mice, Inbred C57BL; Mice, Obese; Receptors, Leptin | 2011 |
The NSAID sulindac is chemopreventive in the mouse distal colon but carcinogenic in the proximal colon.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Drug Evaluation, Preclinical; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation Mediators; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Knockout; MutS Homolog 2 Protein; Precancerous Conditions; Sulindac; Tumor Suppressor Protein p53 | 2011 |
Application of near-infrared fluorescence imaging using a polymeric nanoparticle-based probe for the diagnosis and therapeutic monitoring of colon cancer.
Topics: Adenocarcinoma; Animals; Azoxymethane; Cell Line, Tumor; Colon; Colonic Neoplasms; Diagnostic Imaging; Disease Models, Animal; Disease Progression; Drug Therapy; Enzyme Inhibitors; Fluorescent Dyes; Humans; Male; Matrix Metalloproteinase 7; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred Strains; Nanoparticles; Treatment Outcome; Xenograft Model Antitumor Assays | 2011 |
Dietary astaxanthin inhibits colitis and colitis-associated colon carcinogenesis in mice via modulation of the inflammatory cytokines.
Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Dietary Supplements; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred ICR; NF-kappa B; Tumor Necrosis Factor-alpha; Xanthophylls | 2011 |
Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/β-catenin/cyclin D1 signaling pathway in rats.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antineoplastic Combined Chemotherapy Protocols; Atorvastatin; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Cyclin D1; eIF-2 Kinase; Enzyme-Linked Immunosorbent Assay; Heptanoic Acids; Immunoenzyme Techniques; Interleukin-4; Male; Naproxen; Nitric Oxide Synthase Type II; Pyrroles; Rats; Rats, Inbred F344; Signal Transduction; Sulindac; Tumor Necrosis Factor-alpha | 2011 |
Microsomal prostaglandin E synthase-1 is involved in multiple steps of colon carcinogenesis.
Topics: Aberrant Crypt Foci; Adenocarcinoma; Animals; Azoxymethane; beta Catenin; Carcinogens; Cell Transformation, Neoplastic; Coculture Techniques; Colonic Neoplasms; Colonic Polyps; Cytokines; Gene Expression Profiling; Intramolecular Oxidoreductases; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microsomes; Neoplasm Transplantation; Prostaglandin-E Synthases; Prostaglandins | 2012 |
Enhancement of TGF-β signaling responses by the E3 ubiquitin ligase Arkadia provides tumor suppression in colorectal cancer.
Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Azoxymethane; Base Sequence; Colon; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Mice; Molecular Sequence Data; Mutation; Nuclear Proteins; Proto-Oncogene Proteins; Severity of Illness Index; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases | 2011 |
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Animals, Inbred Strains; Azoxymethane; Cell Transformation, Neoplastic; Chemokines, CXC; Colitis; Colonic Neoplasms; Dermatitis, Contact; Dextran Sulfate; Gene Expression; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Papilloma; Peroxidase; Precancerous Conditions; Receptors, Interleukin-8B; Skin Neoplasms; Statistics, Nonparametric; Tetradecanoylphorbol Acetate; Tumor Burden | 2012 |
Use of a chemically induced-colon carcinogenesis-prone Apc-mutant rat in a chemotherapeutic bioassay.
Topics: Adenocarcinoma; Adenomatous Polyposis Coli Protein; Animals; Antimetabolites, Antineoplastic; Azoxymethane; Colon; Colonic Neoplasms; Dextran Sulfate; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Screening Assays, Antitumor; Fluorouracil; Injections, Intravenous; Male; Mutation; Rats; Reproducibility of Results | 2012 |
Tpl2 regulates intestinal myofibroblast HGF release to suppress colitis-associated tumorigenesis.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colitis; Dextran Sulfate; Hepatocyte Growth Factor; Intestinal Mucosa; Intestinal Neoplasms; Intestines; MAP Kinase Kinase Kinases; Mice; Mice, Knockout; Mucous Membrane; Myofibroblasts; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Signal Transduction | 2012 |
Organomagnesium suppresses inflammation-associated colon carcinogenesis in male Crj: CD-1 mice.
Topics: Adenocarcinoma; Adenoma; Animals; Apoptosis; Azoxymethane; Blotting, Western; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Humans; Immunoenzyme Techniques; Inflammation; Interferon-gamma; Interleukin-1beta; Interleukin-6; Magnesium Compounds; Male; Mice; Mice, Inbred ICR; Mitotic Index; Organometallic Compounds; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2013 |
Comparison of faecal and intestinal concentrations of granulocyte marker protein and localization of gastrointestinal tumours in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Biomarkers, Tumor; Carcinogens; Enzyme-Linked Immunosorbent Assay; Feces; Gastrointestinal Neoplasms; Intestinal Mucosa; Leukocyte L1 Antigen Complex; Models, Animal; Rats; Rats, Sprague-Dawley | 2002 |
Antitumorigenic activity of the prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis on azoxymethane-induced colon carcinogenesis in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azoxymethane; Bifidobacterium; Carcinogens; Cecum; Cell Division; Colonic Neoplasms; Cyclooxygenase 2; Diet; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Induction; Fatty Acids, Volatile; Gastrointestinal Contents; Glutathione S-Transferase pi; Glutathione Transferase; Intestinal Mucosa; Inulin; Isoenzymes; Lactobacillus; Male; Neoplasm Proteins; Oligosaccharides; Probiotics; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344 | 2002 |
Multistage gene expression profiling in a differentially susceptible mouse colon cancer model.
Topics: Adenocarcinoma; Algorithms; Alkylating Agents; Animals; Azoxymethane; Carcinogens; Cluster Analysis; Colonic Neoplasms; Disease Progression; DNA, Complementary; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred A; Mice, Inbred AKR; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Species Specificity; Subtraction Technique | 2003 |
Consumption of black beans and navy beans (Phaseolus vulgaris) reduced azoxymethane-induced colon cancer in rats.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Azoxymethane; Body Composition; Colon; Colonic Neoplasms; Fatty Acids, Volatile; Gastrointestinal Contents; Ileum; Incidence; Male; Phaseolus; Random Allocation; Rats; Rats, Inbred F344; Starch; Weight Gain | 2002 |
Enhancement of colon carcinogenesis by prostaglandin E2 administration.
Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Bromodeoxyuridine; Carcinogens; Colon; Colonic Neoplasms; Dinoprostone; Disease Progression; DNA Primers; Incidence; Injections, Intraperitoneal; Intestinal Mucosa; Male; Rats; Rats, Inbred F344; Receptors, Prostaglandin E; Reverse Transcriptase Polymerase Chain Reaction | 2003 |
Parp-1 deficiency implicated in colon and liver tumorigenesis induced by azoxymethane.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; beta Catenin; Carcinogens; Cell Transformation, Neoplastic; Colonic Neoplasms; Cytoskeletal Proteins; Disease Progression; DNA Primers; Female; Homozygote; Liver Neoplasms, Experimental; Mice; Mice, Inbred ICR; Mice, Knockout; Poly(ADP-ribose) Polymerases; Trans-Activators | 2003 |
The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development.
Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; CDX2 Transcription Factor; Colonic Neoplasms; Genes, Tumor Suppressor; Homeodomain Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagens; Reverse Transcriptase Polymerase Chain Reaction; Trans-Activators | 2003 |
Suppression by nimesulide of bombesin-enhanced peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Bombesin; Carcinogens; Disease Models, Animal; Intestinal Neoplasms; Lymphatic Metastasis; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Peritoneal Neoplasms; Rats; Rats, Wistar; Sulfonamides | 2003 |
A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate.
Topics: Adenocarcinoma; Adenoma; Animals; Anticoagulants; Azoxymethane; beta Catenin; Carcinogens; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Dextran Sulfate; Disease Models, Animal; Inflammation; Injections, Intraperitoneal; Isoenzymes; Male; Mast Cells; Mice; Mice, Inbred ICR; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Trans-Activators; Tumor Suppressor Protein p53 | 2003 |
Intake of beer inhibits azoxymethane-induced colonic carcinogenesis in male Fischer 344 rats.
Topics: Adenocarcinoma; Adenoma; Administration, Oral; Animals; Azoxymethane; Beer; Body Weight; Carcinogens; Colonic Neoplasms; Comet Assay; DNA Damage; Intestinal Mucosa; Male; Rats; Rats, Inbred F344 | 2004 |
Analysis of beta-catenin, Ki-ras, and microsatellite stability in azoxymethane-induced colon tumors of BDIX/Orl Ico rats.
Topics: Adenocarcinoma; Animals; Azoxymethane; beta Catenin; Colonic Neoplasms; Cytoskeletal Proteins; DNA Mutational Analysis; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Immunoenzyme Techniques; Male; Microsatellite Repeats; Polymerase Chain Reaction; Proto-Oncogene Mas; Rats; Rats, Inbred Strains; Trans-Activators | 2003 |
Dietary sodium gluconate protects rats from large bowel cancer by stimulating butyrate production.
Topics: Adenocarcinoma; Adenoma; Animals; Apoptosis; Azoxymethane; beta Catenin; Butyrates; Carcinogens; Cecum; Colon; Colorectal Neoplasms; Cytoskeletal Proteins; Deoxycholic Acid; Diet; Gluconates; Immunohistochemistry; In Situ Nick-End Labeling; Intestines; Male; Organ Size; Rats; Rats, Inbred F344; Trans-Activators | 2004 |
Attenuation by cyclic phosphatidic acid of peritoneal metastasis of azoxymethane-induced intestinal cancers in Wistar rats.
Topics: Adenocarcinoma; Animals; Azoxymethane; Cyclic AMP; Intestinal Neoplasms; Lysophospholipids; Male; Neoplasm Invasiveness; Peritoneal Neoplasms; Rats; Rats, Wistar; rhoA GTP-Binding Protein | 2004 |
Tumor formation is correlated with expression of beta-catenin-accumulated crypts in azoxymethane-induced colon carcinogenesis in mice.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; beta Catenin; Biomarkers, Tumor; Carcinogens; Colonic Neoplasms; Cytoskeletal Proteins; Genetic Predisposition to Disease; Intestinal Mucosa; Mice; Mice, Inbred AKR; Mucins; Neoplasm Proteins; Specific Pathogen-Free Organisms; Trans-Activators | 2004 |
Dietary seed oil rich in conjugated linolenic acid from bitter melon inhibits azoxymethane-induced rat colon carcinogenesis through elevation of colonic PPARgamma expression and alteration of lipid composition.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Azoxymethane; Colonic Neoplasms; Dietary Fats; Incidence; Intestinal Mucosa; Linoleic Acids, Conjugated; Male; Momordica charantia; Phytotherapy; Plant Oils; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2004 |
Sequential observations on the occurrence of preneoplastic and neoplastic lesions in mouse colon treated with azoxymethane and dextran sodium sulfate.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Immunoenzyme Techniques; Incidence; Injections, Intraperitoneal; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; Precancerous Conditions; Tyrosine | 2004 |
Prostaglandin E receptor subtype EP(1) deficiency inhibits colon cancer development.
Topics: Adenocarcinoma; Adenoma; Animals; Apoptosis; Azoxymethane; Cell Proliferation; Colonic Neoplasms; Mice; Mice, Knockout; Protein Kinase C; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype | 2005 |
Beta-Catenin mutations in a mouse model of inflammation-related colon carcinogenesis induced by 1,2-dimethylhydrazine and dextran sodium sulfate.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Azoxymethane; beta Catenin; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Dextran Sulfate; Disease Models, Animal; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred ICR; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Trans-Activators | 2005 |
Induction by lysophosphatidic acid of peritoneal and pleural metastases of intestinal cancers induced by azoxymethane in Wistar rats.
Topics: Adenocarcinoma; Animals; Azoxymethane; Body Weight; Carcinogens; Colonic Neoplasms; Intestinal Neoplasms; Lysophospholipids; Male; Peritoneal Neoplasms; Pleural Neoplasms; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; rhoA GTP-Binding Protein | 2005 |
Senna and the formation of aberrant crypt foci and tumors in rats treated with azoxymethane.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Azoxymethane; Cathartics; Colonic Neoplasms; Male; Phytotherapy; Precancerous Conditions; Rats; Rats, Wistar; Senna Extract; Senna Plant | 2005 |
Strain differences in the susceptibility to azoxymethane and dextran sodium sulfate-induced colon carcinogenesis in mice.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Dextran Sulfate; Disease Susceptibility; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA | 2006 |
Azoxymethane is a genetic background-dependent colorectal tumor initiator and promoter in mice: effects of dose, route, and diet.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colon; Colorectal Neoplasms; Crosses, Genetic; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnancy; Research Design; Species Specificity | 2005 |
Noninvasive monitoring of colonic carcinogenesis: feasibility of [(18)F]FDG-PET in the azoxymethane model.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colonic Neoplasms; Disease Models, Animal; Feasibility Studies; Fluorodeoxyglucose F18; Male; Metabolic Clearance Rate; Organ Specificity; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Inbred F344; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution | 2006 |
The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Azoxymethane; Biomarkers, Tumor; Bromodeoxyuridine; Carcinogens; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin A; Cyclin A2; Cyclin B; Cyclin B1; Dextran Sulfate; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubule-Associated Proteins; Neoplasm Proteins; Neoplasms, Experimental; Polymerase Chain Reaction; Proteins; Repressor Proteins; RNA, Neoplasm; RNA, Small Interfering; RNA, Untranslated; Survivin; TCF Transcription Factors; Transcription Factor 7-Like 2 Protein | 2007 |
Reovirus decreases azoxymethane-induced aberrant crypt foci and colon cancer in a rodent model.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; CD8-Positive T-Lymphocytes; Colonic Neoplasms; Female; Lymphocytes; Male; Orthoreovirus; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 2007 |
Chemopreventive effect of a vitamin D(3) analog, alfacalcidol, on colorectal carcinogenesis in mice with ulcerative colitis.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Azoxymethane; Colitis, Ulcerative; Colorectal Neoplasms; Dextran Sulfate; Female; Hydroxycholecalciferols; Mice; Mice, Inbred CBA; RNA, Messenger; Thymidine Kinase | 2007 |
Helicobacter hepaticus promotes azoxymethane-initiated colon tumorigenesis in BALB/c-IL10-deficient mice.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colitis; Colon; Colonic Neoplasms; Helicobacter hepaticus; Helicobacter Infections; Interleukin-10; Mice; Mice, Inbred BALB C; Mice, Knockout | 2008 |
Altered gene expression in rat colonic adenocarcinomas induced in an azoxymethane plus 2-amino-1-methyl-6-phenylimidazo[4,5-b]- pyridine initiation-promotion model.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Imidazoles; Male; Oligonucleotide Array Sequence Analysis; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; STAT1 Transcription Factor; Vascular Endothelial Growth Factor A | 2007 |
Dietary cooked navy beans and their fractions attenuate colon carcinogenesis in azoxymethane-induced ob/ob mice.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colonic Neoplasms; Fabaceae; Male; Mice; Mice, Obese; Plant Extracts; Random Allocation; Solubility | 2008 |
Effect of dietary wheat bran and dehydrated citrus fiber on azoxymethane-induced intestinal carcinogenesis in Fischer 344 rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azo Compounds; Azoxymethane; Cellulose; Colonic Neoplasms; Dietary Fiber; Edible Grain; Fruit; Intestinal Neoplasms; Male; Neoplasms, Experimental; Rats; Rats, Inbred F344 | 1981 |
Tumor promotion by dietary fat in azoxymethane-induced colon carcinogenesis in female F344 rats: influence of amount and source of dietary fat.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Body Weight; Colonic Neoplasms; Dietary Fats; Feces; Female; Intestinal Neoplasms; Oils; Rats; Rats, Inbred F344; Sterols | 1984 |
Absence of p53 gene mutations in rat colon carcinomas induced by azoxymethane.
Topics: Adenocarcinoma; Animals; Azoxymethane; Base Sequence; Carcinogens; Colonic Neoplasms; DNA Primers; Genes, p53; Male; Molecular Sequence Data; Mutagens; Point Mutation; Polymorphism, Single-Stranded Conformational; Rats; Rats, Inbred F344 | 1995 |
Suppression by amiloride of bombesin-enhanced peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane.
Topics: Adenocarcinoma; Amiloride; Animals; Anticarcinogenic Agents; Azoxymethane; Bombesin; Drug Interactions; Intestinal Neoplasms; Male; Peritoneal Neoplasms; Rats; Rats, Wistar | 1995 |
Histochemical studies of progressive p53 mutations during colonic carcinogenesis in Sprague-Dawley rats induced by N-methyl-N-nitro-nitrosoguanidine or azoxymethane.
Topics: Adenocarcinoma; Animals; Azoxymethane; Cell Nucleus; Colonic Neoplasms; Cytoplasm; Epithelium; Gene Expression; Genes, p53; Immunohistochemistry; Male; Methylnitronitrosoguanidine; Mutation; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53 | 1994 |
Attenuation of vasoactive intestinal peptide enhancement of colon carcinogenesis by ornithine decarboxylase inhibitor.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Diamines; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Random Allocation; Rats; Rats, Wistar; Vasoactive Intestinal Peptide | 1995 |
Enhancement by peptide histidine isoleucine of experimental carcinogenesis in the colon of rats induced by azoxymethane.
Topics: Adenocarcinoma; Animals; Azoxymethane; Body Weight; Colon; Colonic Neoplasms; Drug Synergism; Gastrins; Intestinal Mucosa; Peptide PHI; Rats; Rats, Wistar | 1995 |
Effects of apple pectin on fecal bacterial enzymes in azoxymethane-induced rat colon carcinogenesis.
Topics: Adenocarcinoma; Animals; Azoxymethane; beta-Glucosidase; Body Weight; Carcinoma, Signet Ring Cell; Colonic Neoplasms; Feces; Fruit; Glucuronidase; Male; Pectins; Rats; Tryptophanase | 1995 |
Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colonic Neoplasms; Drug Screening Assays, Antitumor; Hydroxyeicosatetraenoic Acids; Male; Pharmaceutical Vehicles; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositol Phosphates; Phosphoinositide Phospholipase C; Phospholipases A; Phospholipases A2; Phosphoric Diester Hydrolases; Prostaglandins; Rats; Rats, Inbred F344; Sulindac; Thromboxanes | 1995 |
Transglutaminase in azoxymethane-induced colon cancer in the rat.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colon; Colonic Neoplasms; Immunoenzyme Techniques; Intestine, Small; Male; Rats; Rats, Sprague-Dawley; Transglutaminases | 1995 |
Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice.
Topics: Adenocarcinoma; Adenoma; Adenoma, Villous; Animals; Azoxymethane; Benzo(a)pyrene; Carcinogens; Colonic Neoplasms; Curcumin; Duodenal Neoplasms; Female; Male; Methylnitronitrosoguanidine; Mice; Stomach Neoplasms | 1994 |
Ornithine decarboxylase inhibitor attenuates bombesin enhancement of intestinal carcinogenesis and metastasis induced by azoxymethane.
Topics: Adenocarcinoma; Animals; Azoxymethane; Body Weight; Bombesin; Cell Division; Diamines; Drug Synergism; Gastrins; Intestinal Mucosa; Intestinal Neoplasms; Male; Neoplasm Metastasis; Ornithine Decarboxylase Inhibitors; Peritoneal Neoplasms; Rats; Rats, Wistar | 1994 |
Aberrant crypt foci and colon tumors in F344 rats have similar increases in proliferative activity.
Topics: Adenocarcinoma; Animals; Azoxymethane; beta-N-Acetylhexosaminidases; Bromodeoxyuridine; Cell Division; Colon; Colonic Neoplasms; Histocytochemistry; Immunohistochemistry; Male; Rats; Rats, Inbred F344 | 1994 |
Dietary carbohydrates modify azoxymethane-induced intestinal carcinogenesis in rats.
Topics: Adenocarcinoma; Adenoma; Amylose; Animals; Azoxymethane; Calcium; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Intestinal Neoplasms; Male; Rats; Rats, Sprague-Dawley; Starch | 1994 |
Sequential analysis of K-ras mutations in aberrant crypt foci and colonic tumors induced by azoxymethane in Fischer-344 rats on high-risk diet.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colonic Neoplasms; Diet; DNA, Neoplasm; Genes, ras; Male; Mutagenesis; Rats; Rats, Inbred F344 | 1994 |
Immunohistochemical demonstration of mutant p53 tumour suppressor gene product in aberrant crypt foci.
Topics: Adenocarcinoma; Animals; Azoxymethane; Cell Nucleus; Colonic Neoplasms; Cytoplasm; Genes, Tumor Suppressor; Immunohistochemistry; Male; Mutation; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53 | 1993 |
Inhibitory effect of aspirin on azoxymethane-induced colon carcinogenesis in F344 rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Aspirin; Azoxymethane; Body Weight; Colonic Neoplasms; Dinoprostone; Male; Rats; Rats, Inbred F344 | 1993 |
Chemoprevention of colon carcinogenesis by the natural product of a simple phenolic compound protocatechuic acid: suppressing effects on tumor development and biomarkers expression of colon tumorigenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Antineoplastic Agents; Azoxymethane; Biomarkers, Tumor; Cell Division; Colon; Colonic Neoplasms; Drug Screening Assays, Antitumor; Hydroxybenzoates; Intestinal Mucosa; Liver; Male; Nucleolus Organizer Region; Organ Size; Ornithine Decarboxylase; Rats; Rats, Inbred F344 | 1993 |
Alpha 1-antitrypsin as a biomarker in azoxymethane induced intestinal tumors in F344 rats.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoma; alpha 1-Antitrypsin; Animals; Azoxymethane; Biomarkers, Tumor; Colonic Neoplasms; Intestinal Neoplasms; Intestine, Small; Male; Rats; Rats, Inbred F344; Sensitivity and Specificity | 1993 |
K-ras mutations in aberrant crypt foci, adenomas and adenocarcinomas during azoxymethane-induced colon carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Base Sequence; Blotting, Southern; Colon; Colonic Neoplasms; Female; Genes, ras; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred F344 | 1993 |
Chemopreventive effect of oltipraz during different stages of experimental colon carcinogenesis induced by azoxymethane in male F344 rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Azoxymethane; Colonic Neoplasms; Drug Administration Schedule; Drug Screening Assays, Antitumor; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1993 |
Chemoprevention of colon cancer by dietary curcumin.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Curcumin; Diet; Intestinal Mucosa; Lipoxygenase; Male; Ornithine Decarboxylase; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Rats; Rats, Inbred F344 | 1995 |
Cyclooxygenase-1 and cyclooxygenase-2 gene expression in human colorectal adenocarcinomas and in azoxymethane induced colonic tumours in rats.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Animals; Azoxymethane; Base Sequence; Carcinogens; Colonic Neoplasms; Colorectal Neoplasms; Female; Gene Expression; Humans; Male; Middle Aged; Molecular Sequence Data; Oligonucleotide Probes; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Rats; RNA, Messenger | 1996 |
Piroxicam-induced regression of azoxymethane-induced aberrant crypt foci and prevention of colon cancer in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Drug Screening Assays, Antitumor; Male; Piroxicam; Precancerous Conditions; Rats; Rats, Inbred F344 | 1996 |
Dietary fat and fiber differentially alter intracellular second messengers during tumor development in rat colon.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Ceramides; Cocarcinogenesis; Colon; Colorectal Neoplasms; Dietary Fats; Dietary Fiber; Diglycerides; Intestinal Mucosa; Isoenzymes; Phospholipase C gamma; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Type C Phospholipases | 1996 |
Protein kinase C isoforms in the chemopreventive effects of a novel vitamin D3 analogue in rat colonic tumorigenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Azoxymethane; Calcitriol; Chemoprevention; Colon; Colonic Neoplasms; Down-Regulation; Isoenzymes; Male; Protein Kinase C; Rats; Rats, Inbred F344; Up-Regulation | 1996 |
Triamterene suppresses bombesin-enhanced peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane.
Topics: Adenocarcinoma; Animals; Azoxymethane; Bombesin; Calcium; Diuretics; Intestinal Neoplasms; Male; Peritoneal Neoplasms; Rats; Rats, Wistar; Triamterene | 1996 |
The effect of dietary fat on the promotion of mammary and colon cancer in a dual-organ rat carcinogenesis model.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Dietary Fats; Energy Intake; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Chemoprevention of colon carcinogenesis by dietary perillyl alcohol.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Colonic Neoplasms; Diet; Male; Monoterpenes; Rats; Rats, Inbred F344; Terpenes | 1997 |
Chemoprevention of colon cancer by organoselenium compounds and impact of high- or low-fat diets.
Topics: Adenocarcinoma; Analysis of Variance; Animals; Anticarcinogenic Agents; Azoxymethane; Colonic Neoplasms; Cyanates; Dietary Fats; Dose-Response Relationship, Drug; Incidence; Logistic Models; Male; Neoplasm Invasiveness; Organoselenium Compounds; Rats; Rats, Inbred F344 | 1997 |
Increased expression of inducible and endothelial constitutive nitric oxide synthases in rat colon tumors induced by azoxymethane.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colonic Neoplasms; Endothelium; Enzyme Induction; Immunoblotting; Immunohistochemistry; Male; Nitric Oxide Synthase; Rats; Rats, Inbred F344 | 1997 |
Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Biomarkers, Tumor; Caffeic Acids; Carcinogens; Colonic Neoplasms; Curcumin; Isothiocyanates; Male; Rats; Rats, Inbred F344; Sulindac | 1997 |
Expression of bcl-2, bax, and bcl-XL proteins in azoxymethane-induced rat colonic adenocarcinomas.
Topics: Adenocarcinoma; Animals; Azoxymethane; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Carcinogens; Colon; Colonic Neoplasms; Immunohistochemistry; Intestinal Mucosa; Male; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reference Values | 1997 |
Inhibition of azoxymethane-initiated colon tumor by bovine lactoferrin administration in F344 rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinoma; Cattle; Colonic Neoplasms; Incidence; Intestinal Neoplasms; Intestine, Large; Intestine, Small; Lactoferrin; Male; Rats; Rats, Inbred F344 | 1997 |
Enhancement of experimental colon cancer by genistein.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Dinoprost; Drug Synergism; F2-Isoprostanes; Genistein; Hydroxyprostaglandin Dehydrogenases; Intestinal Mucosa; Isoflavones; Male; Neoplasms, Experimental; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344 | 1997 |
Inhibition by ginsenoside Rg3 of bombesin-enhanced peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Bombesin; Carcinogens; Ginsenosides; Intestinal Neoplasms; Male; Neoplasm Metastasis; Peritoneal Neoplasms; Rats; Rats, Wistar; Saponins | 1997 |
Dry beans inhibit azoxymethane-induced colon carcinogenesis in F344 rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Caseins; Colonic Neoplasms; Dietary Fiber; Fabaceae; Male; Plants, Medicinal; Rats; Rats, Inbred F344; Weight Gain | 1997 |
Beta-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors.
Topics: Adenocarcinoma; Animals; Azoxymethane; Base Sequence; beta Catenin; Carcinogens; Colonic Neoplasms; Cytoskeletal Proteins; Male; Molecular Sequence Data; Neoplasm Proteins; Neoplasms, Experimental; Point Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Trans-Activators | 1998 |
Relationship between fecal bile acids and the occurrence of colorectal neoplasia in experimental murine ulcerative colitis.
Topics: Adenocarcinoma; Animals; Azoxymethane; Bile Acids and Salts; Carcinogenicity Tests; Carcinogens; Chromatography, High Pressure Liquid; Colitis, Ulcerative; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Mice; Severity of Illness Index | 1998 |
The nuclear eicosanoid receptor, PPARgamma, is aberrantly expressed in colonic cancers.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Eicosanoids; Gene Expression Regulation, Neoplastic; Humans; Male; Nuclear Proteins; Protein Biosynthesis; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; RNA, Messenger; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
Fish oil blocks azoxymethane-induced rat colon tumorigenesis by increasing cell differentiation and apoptosis rather than decreasing cell proliferation.
Topics: Adenocarcinoma; Aging; Animals; Apoptosis; Azoxymethane; Carcinogens; Cell Differentiation; Cell Division; Colon; Colonic Neoplasms; Dietary Fats; Dietary Fiber; Fish Oils; Male; Rats; Rats, Sprague-Dawley | 1998 |
Absence of an inhibitory effect of a vegetables-fruit mixture on the initiation and promotion phases of azoxymethane-induced colorectal carcinogenesis in rats fed low- or high-fat diets.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Diet; Diet, Fat-Restricted; Dietary Fats; Fruit; Male; Rats; Rats, Inbred F344; Vegetables | 1998 |
Cyclooxygenase-independent chemoprevention with an aspirin derivative in a rat model of colonic adenocarcinoma.
Topics: Adenocarcinoma; Animals; Aspirin; Azoxymethane; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Isoenzymes; Male; Membrane Proteins; Mice; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid | 1998 |
Mutations of the Apc gene in experimental colorectal carcinogenesis induced by azoxymethane in F344 rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colorectal Neoplasms; DNA, Neoplasm; Epithelium; Genes, APC; Intestinal Mucosa; Male; Mutation; Polymerase Chain Reaction; Precancerous Conditions; Rats; Rats, Inbred F344 | 1998 |
Effect of retinoids on AOM-induced colon cancer in rats: modulation of cell proliferation, apoptosis and aberrant crypt foci.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Body Weight; Carcinogens; Colon; Colonic Neoplasms; Drug Screening Assays, Antitumor; Fenretinide; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Tretinoin | 1999 |
Azoxymethane-induced aberrant crypt foci and colorectal tumors in F344 rats: sequential analysis of growth.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinoma, Signet Ring Cell; Cell Division; Colorectal Neoplasms; Hyperplasia; Intestinal Mucosa; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1999 |
Expression of the cyclin D1 gene in rat colorectal aberrant crypt foci and tumors induced by azoxymethane.
Topics: Adenocarcinoma; Animals; Azoxymethane; Bromodeoxyuridine; Cell Division; Cell Nucleus; Colorectal Neoplasms; Cyclin D1; Cytoplasm; Gene Expression; Hyperplasia; Intestinal Mucosa; Male; Rats; Rats, Inbred F344; Time Factors | 1999 |
Chemopreventive efficacy of sulindac sulfone against colon cancer depends on time of administration during carcinogenic process.
Topics: Adenocarcinoma; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colonic Neoplasms; Cyclooxygenase Inhibitors; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Neoplasm Invasiveness; Rats; Rats, Inbred F344; Sulindac; Weight Gain | 1999 |
Modifying effects of a flavonoid morin on azoxymethane-induced large bowel tumorigenesis in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Antioxidants; Azoxymethane; Carcinogens; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Glutathione Transferase; Male; Polyamines; Precancerous Conditions; Rats; Rats, Inbred F344 | 1999 |
Chemopreventive effect of S-methylmethane thiosulfonate and sulindac administered together during the promotion/progression stages of colon carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alkylating; Azoxymethane; Carcinogens; Colonic Neoplasms; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Male; Methyl Methanesulfonate; Rats; Rats, Inbred F344; Sulindac | 1999 |
Inhibitory effect of microfibril wheat bran on azoxymethane-induced colon carcinogenesis in CF1 mice.
Topics: Adenocarcinoma; Animals; Azoxymethane; Body Weight; Carcinogenicity Tests; Cellulose; Colonic Neoplasms; Dietary Fiber; Dietary Supplements; Fatty Acids, Volatile; Female; Gastrointestinal Contents; Mice; Mice, Inbred Strains | 1999 |
Effect of olive oil on early and late events of colon carcinogenesis in rats: modulation of arachidonic acid metabolism and local prostaglandin E(2) synthesis.
Topics: Adenocarcinoma; Animals; Arachidonic Acid; Azoxymethane; Carcinogens; Chi-Square Distribution; Colon; Colonic Neoplasms; Dietary Fats, Unsaturated; Dinoprostone; Fatty Acids; Fish Oils; Intestinal Mucosa; Male; Olive Oil; Plant Oils; Random Allocation; Rats; Rats, Sprague-Dawley; Safflower Oil; Statistics, Nonparametric | 2000 |
Termination of piroxicam treatment and the occurrence of azoxymethane-induced colon cancer in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azoxymethane; Body Weight; Carcinogenicity Tests; Carcinogens; Cell Division; Colonic Neoplasms; Disease Progression; Drug Administration Schedule; Intestinal Mucosa; Male; Piroxicam; Precancerous Conditions; Rats; Rats, Inbred F344 | 1999 |
Lack of chemopreventive efficacy of DL-selenomethionine in colon carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Diet; Male; Rats; Rats, Inbred F344; Selenomethionine | 2000 |
Milk and dairy products in cancer prevention: focus on bovine lactoferrin.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Dairy Products; Diet; Dose-Response Relationship, Drug; Intestinal Polyps; Intestines; Lactoferrin; Male; Mice; Mice, Inbred C57BL; Milk; Rats; Rats, Inbred F344 | 2000 |
Obesity potentiates AOM-induced colon cancer.
Topics: Adenocarcinoma; Animals; Azoxymethane; Cell Transformation, Neoplastic; Colonic Neoplasms; Diet, Fat-Restricted; Intestinal Mucosa; Male; Obesity; Rats; Rats, Zucker; Risk Factors | 2000 |
ras p21 Isoprenylation inhibition induces flat colon tumors in Wistar rats.
Topics: Adenocarcinoma; Adenoma; Analysis of Variance; Animals; Antimetabolites; Apoptosis; Azoxymethane; Blotting, Western; Bromodeoxyuridine; Carcinogens; Colonic Neoplasms; Colonic Polyps; Genes, ras; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Oncogene Protein p21(ras); Point Mutation; Pravastatin; Prevalence; Protein Prenylation; Random Allocation; Rats; Rats, Wistar | 2000 |
Altered expression of beta-catenin, inducible nitric oxide synthase and cyclooxygenase-2 in azoxymethane-induced rat colon carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Gene Expression; Genes, ras; Hyperplasia; Isoenzymes; Male; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Subcellular Fractions; Trans-Activators | 2000 |
Expression of transforming growth factor beta1 and its type II receptor in mouse colon tumors induced by azoxymethane.
Topics: Adenocarcinoma; Amino Acid Substitution; Animals; Azoxymethane; Carcinogens; Codon; Colonic Neoplasms; DNA Mutational Analysis; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Male; Mice; Neoplasm Proteins; Point Mutation; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2000 |
Gastrin-releasing peptide is a mitogen and a morphogen in murine colon cancer.
Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Carcinogens; Cell Differentiation; Cell Division; Colonic Neoplasms; Epithelial Cells; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gastrin-Releasing Peptide; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogens; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Receptors, Bombesin | 2000 |
Differential expression of p16(INK4a) in azoxymethane-induced mouse colon tumorigenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, p16; Genes, Retinoblastoma; Male; Mice; Mice, Inbred Strains; Neoplasm Proteins; Polymerase Chain Reaction; Precancerous Conditions; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm | 2000 |
Suppression of azoxymethane-induced colon carcinogenesis in male F344 rats by mandarin juices rich in beta-cryptoxanthin and hesperidin.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; beta Carotene; Beverages; Carcinogens; Citrus; Colonic Neoplasms; Cryptoxanthins; Cyclin D1; Hesperidin; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Xanthophylls | 2000 |
Detection of somatic DNA alterations in azoxymethane-induced F344 rat colon tumors by random amplified polymorphic DNA analysis.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; DNA Damage; DNA Fingerprinting; DNA, Neoplasm; Genes, ras; Male; Microsatellite Repeats; Mutation; Precancerous Conditions; Random Amplified Polymorphic DNA Technique; Rats; Rats, Inbred F344 | 2000 |
Preventive potential of wheat bran fractions against experimental colon carcinogenesis: implications for human colon cancer prevention.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Azoxymethane; Blotting, Western; Body Weight; Carcinogens; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dietary Fiber; Humans; Isoenzymes; Male; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phytic Acid; Plant Oils; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344 | 2000 |
Folate deficiency reduces the development of colorectal cancer in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Colorectal Neoplasms; Folic Acid; Folic Acid Deficiency; Intestinal Neoplasms; Male; Rats; Rats, Sprague-Dawley | 2000 |
Neonatal inoculation with the protein-bound polysaccharide PSK increases resistance of adult animals to challenge with syngeneic tumor cells and reduces azoxymethane-induced precancerous lesions in the colon.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Age Factors; Animals; Animals, Newborn; Azoxymethane; Carcinogens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Precancerous Conditions; Proteoglycans; Rats; Rats, Inbred F344; Survival Analysis | 2000 |
Soy protein isolate consumption protects against azoxymethane-induced colon tumors in male rats.
Topics: Adenocarcinoma; Animals; Azoxymethane; Body Weight; Cell Division; Colonic Neoplasms; Food, Formulated; Male; Rats; Rats, Sprague-Dawley; Soybean Proteins | 2001 |
Enhanced formation of azoxymethane-induced colorectal adenocarcinoma in gammadelta T lymphocyte-deficient mice.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colorectal Neoplasms; Disease Progression; Homozygote; Hyperplasia; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes | 2001 |
High susceptibility of Scid mice to colon carcinogenesis induced by azoxymethane indicates a possible caretaker role for DNA-dependent protein kinase.
Topics: Adenocarcinoma; Animals; Azoxymethane; beta Catenin; Carcinogens; Cocarcinogenesis; Colonic Neoplasms; Cytoskeletal Proteins; DNA-Activated Protein Kinase; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Mice; Mice, SCID; Mutation; Precancerous Conditions; Protein Serine-Threonine Kinases; Trans-Activators | 2001 |
Chemoprevention of azoxymethane-induced rat colon carcinogenesis by dietary capsaicin and rotenone.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Capsaicin; Carcinogens; Colonic Neoplasms; Diet; Dose-Response Relationship, Drug; Glutathione Transferase; Insecticides; Male; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Inbred F344; Rotenone | 2001 |
Effect of bisacodyl and cascara on growth of aberrant crypt foci and malignant tumors in the rat colon.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Bisacodyl; Carcinogens; Colon; Colonic Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Precancerous Conditions; Rats; Rats, Wistar; Rhamnus | 2001 |
Anatomical site-specific response to DNA damage is related to later tumor development in the rat azoxymethane colon carcinogenesis model.
Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Carcinogens; Colonic Neoplasms; DNA Adducts; DNA Damage; DNA Repair; DNA, Neoplasm; Immunoenzyme Techniques; Lipid Metabolism; Male; Methylation; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Sprague-Dawley | 2001 |
Suppression by apigenin of peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apigenin; Azoxymethane; Bombesin; Carcinogens; Flavonoids; Injections, Subcutaneous; Intestinal Neoplasms; Male; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase Kinases; Peritoneal Neoplasms; Phosphorylation; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar | 2000 |
Comparative study of histopathologic characterization of azoxymethane-induced colon tumors in three inbred rat strains.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Biomarkers, Tumor; Carcinogens; Colorectal Neoplasms; Disease Models, Animal; Female; Fluorescent Antibody Technique, Indirect; Immunoenzyme Techniques; Injections, Subcutaneous; Male; Polymorphism, Genetic; Rats; Rats, Inbred F344; Reproducibility of Results; Species Specificity; Time Factors | 2002 |
Effects of lyophilized black raspberries on azoxymethane-induced colon cancer and 8-hydroxy-2'-deoxyguanosine levels in the Fischer 344 rat.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenocarcinoma; Adenoma; Animals; Anthocyanins; Anticarcinogenic Agents; Azoxymethane; Calcium; Cholesterol; Colonic Neoplasms; Coumaric Acids; Deoxyguanosine; Diet; Ellagic Acid; Freeze Drying; Fruit; Oxidative Stress; Rats; Rats, Inbred F344; Rosaceae; Sitosterols | 2001 |
Enhanced colon carcinogenesis induced by azoxymethane in min mice occurs via a mechanism independent of beta-catenin mutation.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Cytoskeletal Proteins; DNA Primers; Male; Mice; Mice, Inbred C57BL; Mutagenesis; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Trans-Activators | 2002 |
Role of the alternating reading frame (P19)-p53 pathway in an in vivo murine colon tumor model.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; DNA, Neoplasm; Gene Expression Regulation; Genes, p53; Male; Mice; Mice, Inbred A; Mice, Inbred AKR; Reading Frames; RNA, Messenger; Transcriptional Activation; Tumor Suppressor Protein p53; Up-Regulation | 2002 |
Dose response to a single injection of azoxymethane in rats. Induction of tumors in the gastrointestinal tract, auditory sebaceous glands, kidney, liver and preputial gland.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Azo Compounds; Azoxymethane; Carcinoma, Squamous Cell; Colon; Colonic Neoplasms; Duodenal Neoplasms; Duodenum; Ear Canal; Hyperplasia; Intestinal Polyps; Kidney; Kidney Neoplasms; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Neoplasms; Rats; Rodent Diseases; Sebaceous Gland Neoplasms | 1975 |
Enhanced colonic carcinogenesis with azoxymethane in rats after pancreaticobiliary diversion to mid small bowel.
Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Ampulla of Vater; Animals; Azo Compounds; Azoxymethane; Bile; Bile Acids and Salts; Body Weight; Carcinoma, Squamous Cell; Colonic Neoplasms; DNA; Duodenal Neoplasms; Intestine, Small; Male; Neoplasms, Experimental; Pancreatic Juice; Rats; RNA | 1979 |
The cytochemical demonstration of beta-glucuronidase in colon neoplasms of rats exposed to azoxymethane.
Topics: Adenocarcinoma; Animals; Azo Compounds; Azoxymethane; Colon; Colonic Neoplasms; Glucuronidase; Intestinal Mucosa; Intestinal Polyps; Lymphatic Metastasis; Male; Neoplasms, Experimental; Rats | 1978 |
Effect of propylthiouracil on intestinal tumor formation by azoxymethane in rats.
Topics: Adenocarcinoma; Animals; Azo Compounds; Azoxymethane; Bile Acids and Salts; Feces; Intestinal Neoplasms; Male; Propylthiouracil; Rats; Steroids | 1977 |
Attenuation by the GABA receptor agonist baclofen of experimental carcinogenesis in rat colon by azoxymethane.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Baclofen; Cell Division; Colon; Colonic Neoplasms; Hyperplasia; Intestinal Mucosa; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
Evidence for a ras gene mutation in azoxymethane-induced colonic aberrant crypts in Sprague-Dawley rats: earliest recognizable precursor lesions of experimental colon cancer.
Topics: Adenocarcinoma; Animals; Azoxymethane; Base Sequence; Colonic Neoplasms; DNA, Single-Stranded; Genes, ras; Immunohistochemistry; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Precancerous Conditions; Proto-Oncogene Proteins p21(ras); Rats; Rats, Sprague-Dawley | 1992 |
Enhancement by bombesin of colon carcinogenesis and metastasis induced by azoxymethane in Wistar rats.
Topics: Adenocarcinoma; Animals; Azoxymethane; Bombesin; Colon; Colonic Neoplasms; Gastrins; Male; Neoplasm Metastasis; Norepinephrine; Rats; Rats, Inbred Strains | 1992 |
Enhancement by thyroxine of experimental carcinogenesis induced in rat colon by azoxymethane.
Topics: Adenocarcinoma; Adenoma; Analysis of Variance; Animals; Azoxymethane; Body Weight; Carcinogens; Colonic Neoplasms; Drug Synergism; Intestinal Mucosa; Male; Mitotic Index; Neoplasm Metastasis; Probability; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine | 1992 |
Inhibition by the dopamine antagonist haloperidol of experimental carcinogenesis induced by azoxymethane in rat colon.
Topics: Adenocarcinoma; Animals; Azoxymethane; Body Weight; Bromocriptine; Colonic Neoplasms; Cyclic AMP; DNA; Dopamine Antagonists; Energy Intake; Haloperidol; Male; Mitotic Index; Rats; Rats, Inbred Strains | 1991 |
Enhanced induction of colon carcinogenesis by azoxymethane in Wistar rats fed a low-protein diet.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Cell Division; Colon; Colonic Neoplasms; Dietary Proteins; Gastrins; Intestinal Mucosa; Male; Norepinephrine; Rats; Rats, Inbred Strains | 1992 |
Inhibition of azoxymethane-induced experimental colon carcinogenesis in Wistar rats by 6-hydroxydopamine.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinoma in Situ; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains | 1992 |
The combined effects of dietary fat, protein, and energy intake on azoxymethane-induced intestinal and renal carcinogenesis.
Topics: Adenocarcinoma; Animals; Azoxymethane; Body Weight; Dietary Fats; Dietary Proteins; Energy Metabolism; Intestinal Neoplasms; Kidney Neoplasms; Male; Rats; Rats, Inbred Strains; Time Factors | 1992 |
Effect of diets high in omega-3 and omega-6 fatty acids on initiation and postinitiation stages of colon carcinogenesis.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colonic Neoplasms; Corn Oil; Dietary Fats; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Fish Oils; Male; Rats; Rats, Inbred F344 | 1991 |
Experimental model of colon cancer: recurrences after surgery alone or associated with intraperitoneal 5-fluorouracil chemotherapy.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Disease Models, Animal; Fluorouracil; Injections, Intraperitoneal; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Prognosis; Random Allocation; Rats | 1991 |
The thalidomide analog, EM 12, enhances 1,2-dimethylhydrazine-induction of rat colon adenocarcinomas.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Azoxymethane; Body Weight; Carcinogens; Colon; Dimethylhydrazines; Drug Synergism; Intestinal Neoplasms; Intestine, Small; Male; Rats; Rats, Inbred Strains; Thalidomide | 1991 |
Enhancement by methionine enkephalin of colon carcinogenesis induced by azoxymethane.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colon; Colonic Neoplasms; Drug Administration Schedule; Drug Synergism; Enkephalin, Methionine; Male; Naloxone; Rats; Rats, Inbred Strains | 1991 |
Inhibition by putrescine of experimental carcinogenesis in rat colon induced by azoxymethane.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Body Weight; Carcinoma in Situ; Cell Transformation, Neoplastic; Colonic Neoplasms; Male; Ornithine Decarboxylase; Putrescine; Rats; Rats, Inbred Strains | 1991 |
Effects of androgen manipulations on chemically induced colonic tumours and on macroscopically normal colonic mucosa in male Sprague-Dawley rats.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colonic Neoplasms; Cyproterone; Cyproterone Acetate; Drug Synergism; Intestinal Mucosa; Male; Mitotic Index; Orchiectomy; Rats; Rats, Inbred Strains; Testosterone | 1990 |
Enhancement by neurotensin of experimental carcinogenesis induced in rat colon by azoxymethane.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Body Weight; Colonic Neoplasms; Drug Synergism; Gastrins; Male; Neurotensin; Rats; Rats, Inbred Strains | 1990 |
Methane excretion and experimental colonic carcinogenesis.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colonic Neoplasms; Male; Methane; Rats; Rats, Inbred F344; Time Factors | 1990 |
Enhancement of azoxymethane-induced colon carcinogenesis in spontaneously hypertensive rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinoma in Situ; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity | 1990 |
Tissue norepinephrine depletion as a mechanism for cysteamine inhibition of colon carcinogenesis induced by azoxymethane in Wistar rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinoma; Cell Division; Colon; Colonic Neoplasms; Cysteamine; Gastrins; Male; Norepinephrine; Rats; Rats, Inbred Strains | 1989 |
An investigation of colon cancer associated with urinary diversion.
Topics: Adenocarcinoma; Adenoma; Anastomosis, Surgical; Animals; Azoxymethane; Colon; Colonic Neoplasms; Male; Mesocolon; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Diversion | 1989 |
Inhibitory effect of dietary p-methoxybenzeneselenol on azoxymethane-induced colon and kidney carcinogenesis in female F344 rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anisoles; Azoxymethane; Colonic Neoplasms; Diet; Female; Kidney Neoplasms; Neoplasms, Multiple Primary; Organoselenium Compounds; Rats; Rats, Inbred F344; Selenium; Wilms Tumor | 1985 |
Inhibition by isoproterenol and neostigmine of experimental carcinogenesis in rat colon by azoxymethane.
Topics: Adenocarcinoma; Animals; Autonomic Nervous System; Azoxymethane; Colonic Neoplasms; Intestinal Mucosa; Isoproterenol; Male; Neostigmine; Rats; Rats, Inbred Strains | 1988 |
The effects of a "low-risk" diet on tumor incidence in chemically induced colon cancer in rats.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colonic Neoplasms; Food, Formulated; Rats; Rats, Inbred F344; Risk Factors | 1988 |
Interactions of selenium deficiency, vitamin E, polyunsaturated fat, and saturated fat on azoxymethane-induced colon carcinogenesis in male F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Dietary Fats; Dimethylhydrazines; Fatty Acids, Unsaturated; Intestinal Neoplasms; Male; Rats; Rats, Inbred F344; Selenium; Vitamin E | 1986 |
Effect of different levels of dietary corn oil and lard during the initiation phase of colon carcinogenesis in F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Azoxymethane; Bile Acids and Salts; Body Weight; Colon; Colonic Neoplasms; Corn Oil; Dietary Fats; Dimethylhydrazines; Eating; Male; Oils; Ornithine Decarboxylase; Rats; Rats, Inbred F344 | 1986 |
Effect of dietary Laminaria angustata (brown seaweed) on azoxymethane-induced intestinal carcinogenesis in male F344 rats.
Topics: Adenocarcinoma; Animals; Azoxymethane; Cholesterol; Colon; Colonic Neoplasms; Intestinal Polyps; Laminaria; Male; Rats; Rats, Inbred F344; Seaweed; Sterols | 1985 |