azoxymethane has been researched along with Aberrant Crypt Foci in 73 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 67 (91.78) | 24.3611 |
2020's | 6 (8.22) | 2.80 |
Authors | Studies |
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Canter, JA; Cao, L; Carlson, BA; Davis, CD; Ernst, SE; Gladyshev, VN; Grysczyk, L; Hatfield, DL; Peters, KM; Thielman, NRJ; Tsuji, PA; Udofe, P; Yu, Y | 1 |
Bailey, MT; Chatelaine, HA; Hatzakis, E; Kopec, RE; Mathé, EA; McElroy, J; Olivo-Marston, S; Ramazani, CA; Spencer, K | 1 |
Aranda-Vargas, PJ; Chávez-Servín, JL; de la Torre-Carbot, K; Ferríz-Martínez, RA; García-Gasca, T; González-Reyes, A; Kuri-García, A; Mejía, C; Moreno Celis, U; Saldaña Gutiérrez, C | 1 |
Gao, Z; Li, G; Liu, H; Zhang, L | 1 |
Aggarwal, A; Baumgartner, M; Gasche, C; Gröschel, C; Heiden, D; Kallay, E; Karuthedom George, S; Lang, M; Manhardt, T; Marculescu, R; Mesteri, I; Prinz-Wohlgenannt, M; Schepelmann, M; Tennakoon, S; Trawnicek, L | 1 |
Bonakdar, S; Emtyazjoo, M; Mostafavi, PG; Sahebi, Z | 1 |
He, C; Hu, M; Li, P; Li, Y; Liu, Q; Liu, S; Shen, J; Sun, Y; Xiao, P; Yang, C; Zhang, Z | 1 |
Álvarez-González, I; García-Cordero, JM; Jiménez-Martínez, C; Madrigal-Bujaidar, E; Madrigal-Santillán, E; Martínez-Palma, NY; Morales-González, JA; Paniagua-Pérez, R | 1 |
Cai, YK; Chen, J; Chen, WJ; Hao, Z; Lv, Y; Wang, HP; Wang, X; Ye, T; Zhao, JY | 1 |
Melo, AFP; Mendonça, MCP; Rosa-Castro, RM | 1 |
Chávez-Servín, JL; Enríquez-Vázquez, A; Ferriz-Martínez, RA; García-Gasca, T; García-Solís, P; Godínez-Santillán, RI; Guzmán-Maldonado, SH; Kuri-García, A; Mejía, C | 1 |
Hasegawa, H; Ishida, T; Kitagawa, Y; Kondo, T; Matsui, S; Okabayashi, K; Sato, T; Seishima, R; Shigeta, K; Shimoda, M; Sugimoto, S; Suzuki, Y; Tsuruta, M | 1 |
Fitch, MD; Fleming, SE; Sikalidis, AK | 2 |
MacLeod, RJ | 1 |
Al-Rabadi, L; Bugni, JM; Karagiannides, I; Pothoulakis, C; Stavrakis, D; Tuominen, I | 1 |
Cooma, I; Kawamori, T; Patlolla, JM; Rao, CV; Steele, VE | 1 |
Amin, S; Choi, CI; Desai, D; Janakiram, NB; Mohammed, A; Rao, CV; Ravillah, D; Zhang, Y | 1 |
Goji, T; Izumi, K; Kimura, T; Kitamura, S; Miyamoto, H; Muguruma, N; Nakagawa, T; Okahisa, T; Okamoto, K; Sannomiya, K; Takayama, T; Tsuda, M | 1 |
Carey, E; Chen, TY; Griffin, J; Herndon, B; Katz, B; Kim, J; Lim, S; Standard, J; Su, X; Tomich, J; Wang, W; Xu, J | 1 |
Hernández, LM; Hong, MY; Nemoseck, T; Nulton, E; Shelechi, M | 1 |
Banerjee, N; Kim, H; Mertens-Talcott, S; Talcott, S | 1 |
Guizani, N; Rahman, MS; Singh, V; Waly, MI | 1 |
Alvarez-Gonzalez, I; Garcia-Aguirre, K; Garcia-Medina, S; Madrigal-Bujaidar, E; Martino Roaro, L | 1 |
Abdulla, MA; Abdullah, NA; Almaqrami, AA; Alsalahi, A; Alshawsh, MA; Hajrezaei, M; Salem, SD; Shwter, AN | 1 |
Abdulla, MA; Ali, HM; Almagrami, AA; Fani, S; Golbabapour, S; Gwaram, NS; Hajrezaie, M; Hassandarvish, P; Kamalidehghan, B; Karimian, H; Majid, NA; Moghadamtousi, SZ; Najihussien, A; Rouhollahi, E; Zahedifard, M | 1 |
Blackler, RW; Elsheikh, W; Flannigan, KL; Wallace, JL | 1 |
Abdulla, MA; Almagrami, AA; Alshawsh, MA; Saif-Ali, R; Salem, SD; Shwter, A | 1 |
Acosta-Gallegos, J; Campos-Vega, R; Feregrino-Perez, AA; Gomez-Arbones, X; Guevara-González, RG; Loarca-Piña, G; Piñol-Felis, C | 1 |
Abdulla, MA; Al-Henhena, N; Ameen Abdulla, M; El-Seedi, H; Ismail, S; Khalifa, SA; Najm, W; Ying, RP | 1 |
Abe, F; Beppu, H; Chihara, T; Higashiguchi, T; Kaneko, T; Shimpo, K; Sonoda, S; Tanaka, M; Yamada, M | 1 |
Campanholo, VM; Forones, NM; Neto, RA; Paiotti, AP; Ribeiro, DA; Silva, RM; Silva, TD | 1 |
Chaiyasut, C; Riengrojpitak, S; Suwannalert, P; Tammasakchai, A | 1 |
Abdul Kadir, H; Ameen Abdulla, M; Fadaeinasab, M; Firoozinia, M; Karimian, H; Rouhollahi, E; Zorofchian Moghadamtousi, S | 1 |
Beppu, H; Chihara, T; Higashiguchi, T; Kaneko, T; Shimpo, K; Sonoda, S | 1 |
Abdulla, MA; Emtyazjoo, M; Hajrezaie, M; Hassandarvish, P; Karimian, H; Majid, NA; Moghadamtousi, SZ; Mohd Ali, H; Shams, K; Zahedifard, M | 1 |
Abd Malek, SN; Abdulla, MA; Al-Henhena, N; Awang, K; Hasanpourghadi, M; Kunasegaran, T; Looi, CY; Moghadamtousi, SZ; Mohamed, Z; Rouhollahi, E | 1 |
Alam, S; Ansari, KM; Kumar, R; Mir, SS; Pal, A | 1 |
Chien, SP; Liu, CT; Liu, MY; Periasamy, S; Wu, WH | 1 |
Baltazar, F; Lima, CF; Pedro, DF; Pereira-Wilson, C; Ramos, AA | 1 |
Anwar, MM; Cohen, SM; Mirvish, SS; Pennington, KL; Shostrom, V; Wisecarver, JL; Zahid, M; Zhou, L | 1 |
Chaiyasut, C; Duangjitcharoen, Y; Pattananandecha, T; Peerajan, S; Sirilun, S; Sivamaruthi, BS; Suwannalert, P | 1 |
Hazilawati, H; Norhaizan, ME; Pandurangan, AK; Roselina, K; Tan, BL | 1 |
Álvarez-González, RI; Dávila-Ortiz, G; Garduño-Siciliano, L; Jiménez-Martínez, C; León-Espinosa, EB; Madrigal-Bujaidar, E; Sánchez-Chino, X; Téllez-Medina, DI | 1 |
Chaiyasut, C; Reungpatthanaphong, S; Sirilun, S; Suwannalert, P | 1 |
Allred, CD; Callaway, ES; Chapkin, RS; Davidson, LA; Hensel, ME; Jayaprakasha, GK; Kim, E; Patil, BS; Salinas, ML; Turner, ND; Weeks, BR; Zoh, RS | 1 |
Banerjee, N; Byrne, DH; Kim, H; Mertens-Talcott, SU; Talcott, ST; Turner, ND | 1 |
Chen, X; Li, F; Lin, L; Liu, S; Lou, X; Pan, Q; Shan, Q; Su, S; Wei, H; Wu, L; Xie, Y; Zhang, J; Zhu, Y | 1 |
Burlamaqui, IM; Carvalho, ER; Dornelas, CA; Escalante, RD; Mesquita, FJ; Mota, DM; Rodrigues, LV; Veras, LB | 1 |
Cheng, AC; Ho, CT; Lai, CS; Li, S; Lo, CY; Pan, MH; Tsai, ML; Wang, Y; Wang, YJ; Xiao, H | 1 |
Dinda, AK; Muralikrishnan, G; Shakeel, F | 1 |
Ghafar, SA; Ismail, M; Tahir, PM; Yazan, LS | 1 |
Imai, T; Masuda, S; Mutoh, M; Nakano, K; Sugimura, T; Takahashi, M; Takasu, S; Teraoka, N; Ueno, T; Wakabayashi, K | 1 |
Aziz, SA; Caldwell, D; Mehta, R; Raju, J; Roberts, J; Sondagar, C; Vavasour, E | 1 |
Ball-Kell, S; Bie, W; Carroll, RE; Gierut, J; Haegebarth, A; Tyner, AL; Zheng, Y | 1 |
Al-Numair, KS; Ali, A; Alsaif, MA; Essa, MM; Farhat, MF; Waly, MI | 1 |
Akira, S; Hara, S; Ishii, T; Ishikawa, Y; Kamei, D; Murakami, M; Sasaki, Y; Uematsu, S | 1 |
Burlamaqui, IM; Dornelas, CA; Mesquita, FJ; Mota, DM; Rodrigues, LV; Valença Júnior, JT; Vasconcelos, PR; Veras, LB | 1 |
Corpet, DE; Davis, ME; Gulizia, JM; Lisowyj, MP; Mirvish, SS; Naud, N; Shostrom, VK; Wisecarver, JL; Zhou, L | 1 |
Bauer-Marinovic, M; Dobbernack, G; Florian, S; Glatt, H; Meinl, W; Monien, BH; Taugner, F | 1 |
Achour, L; El Felah, M; Hammami, M; Lahouar, L; Magne, F; Mangin, I; Mokni, M; Pereira, E; Pochart, P; Salem, HB; Suau, A | 1 |
Dubeykovskiy, A; Jin, G; Ramanathan, V; Takaishi, S; Wang, TC; Westphalen, CB; Whelan, A | 1 |
Hirata, A; Kato, N; Ohata, T; Sanada, Y; Toya, K; Yanaka, N | 1 |
Chen, H; Li, Q; Zhang, Y; Zhou, D | 1 |
Ananda Sadagopan, SK; Dharmalingam, P; Ganapasam, S; Pandurangan, AK | 1 |
Chaiyasut, C; Rattanachitthawat, S; Reungpatthanaphong, S; Suwannalert, P; Tammasakchai, A | 1 |
Al-Rawahi, AS; Ali, A; Farooq, SA; Guizani, N; Rahman, MS; Waly, MI | 1 |
Fujii, G; Komiya, M; Mutoh, M; Nakano, K; Takahashi, M; Takasu, S; Teraoka, N; Ueno, T; Wakabayashi, K; Yamamoto, M; Yanaka, A | 1 |
Chong, PP; Ho, KL; Ismail, M; Yazan, LS | 1 |
Ji, P; Ouyang, N; Williams, JL | 1 |
Ho, CT; Lai, CS; Li, S; Liu, CB; Miyauchi, Y; Pan, MH; Suzawa, M | 1 |
Kashimoto, N; Tamura, K; Ushijima, M; Watanabe, H | 1 |
Baek, SJ; Imchen, T; Manasse, J; Min, KW | 1 |
73 other study(ies) available for azoxymethane and Aberrant Crypt Foci
Article | Year |
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Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogenesis; Colonic Neoplasms; Cytokines; Dextran Sulfate; Diet; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Intestinal Mucosa; Male; Mice; Mice, Knockout; Selenoproteins; Signal Transduction; Sodium Selenite; Trace Elements | 2021 |
Dietary Energy Intake and Presence of Aberrant Crypt Foci Are Associated with Phospholipid, Purine, and Taurine Metabolite Abundances in C57BL/6N Mouse Colon.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Diet; Energy Intake; Mice; Mice, Inbred C57BL; Phospholipids; Precancerous Conditions; Purines; Taurine | 2022 |
Effect on nutritional markers of a model of aberrant crypt foci induced by azoxymethane and sodium dextran sulfate in Sprague Dawley rats.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Male; Nutritional Physiological Phenomena; Rats; Rats, Sprague-Dawley | 2019 |
Xanthohumol protects against Azoxymethane-induced colorectal cancer in Sprague-Dawley rats.
Topics: Aberrant Crypt Foci; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Azoxymethane; Cell Proliferation; Colorectal Neoplasms; Flavonoids; Humans; Male; Propiophenones; Rats; Rats, Sprague-Dawley | 2020 |
Switching to a Healthy Diet Prevents the Detrimental Effects of Western Diet in a Colitis-Associated Colorectal Cancer Model.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Diet, Healthy; Diet, Western; Disease Models, Animal; Female; Gastrointestinal Microbiome; Liver; Mice; Mice, Inbred BALB C; Vitamin D | 2019 |
Promising Chemoprevention of Colonic Aberrant Crypt Foci by
Topics: Aberrant Crypt Foci; Animals; Antineoplastic Agents; Antioxidants; Azoxymethane; Biphenyl Compounds; Brachyura; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Injections, Intradermal; Male; Molecular Structure; Muscles; Neoplasms, Experimental; Picrates; Rats; Rats, Wistar; Structure-Activity Relationship; Tumor Cells, Cultured | 2020 |
The chemopreventive effects of Huangqin-tea against AOM-induced preneoplastic colonic aberrant crypt foci in rats and omics analysis.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Colonic Neoplasms; Disease Models, Animal; Functional Food; Male; Rats; Rats, Wistar; Scutellaria baicalensis; Tea | 2020 |
Phaseolin, a Protein from the Seed of
Topics: Aberrant Crypt Foci; Animals; Antioxidants; Azoxymethane; Chemical and Drug Induced Liver Injury; Chemoprevention; Colitis; Colon; Disease Models, Animal; DNA Damage; Male; Mice; Oxidation-Reduction; Oxidative Stress; Phaseolus; Plant Extracts; Protective Agents; Seeds | 2021 |
Structural shift of gut microbiota during chemo-preventive effects of epigallocatechin gallate on colorectal carcinogenesis in mice.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Carcinogens; Catechin; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Microbiome; Humans; Mice; Rectum; RNA, Ribosomal, 16S | 2017 |
The protective effects of fermented kefir milk on azoxymethane-induced aberrant crypt formation in mice colon.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Female; Kefir; Mice; Mice, Inbred BALB C | 2018 |
Preventive Effect of an Infusion of the Aqueous Extract of Chaya Leaves (
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Colon; Dextran Sulfate; Disease Models, Animal; Euphorbiaceae; Humans; Male; Plant Extracts; Plant Leaves; Protective Agents; Rats; Rats, Sprague-Dawley | 2019 |
Interleukin-13 and its signaling pathway is associated with obesity-related colorectal tumorigenesis.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Interleukin-13; Mice; Mice, Inbred C57BL; Obesity; Peritoneal Absorption; Receptors, Interleukin-13; Signal Transduction; Up-Regulation | 2019 |
Diet induced obesity increases the risk of colonic tumorigenesis in mice.
Topics: Aberrant Crypt Foci; Analysis of Variance; Animals; Azoxymethane; Body Weight; Carcinogenesis; Carcinogens; Colonic Neoplasms; Energy Intake; Male; Mice; Mice, Inbred C57BL; Obesity; Random Allocation; Weight Gain | 2013 |
Extracellular calcium-sensing receptor/PTH knockout mice colons have increased Wnt/β-catenin signaling, reduced non-canonical Wnt signaling, and increased susceptibility to azoxymethane-induced aberrant crypt foci.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; beta Catenin; Blotting, Western; Colon; Cyclin D1; Genetic Predisposition to Disease; Intestine, Small; Matrix Metalloproteinase 7; Mice; Mice, Knockout; Parathyroid Hormone; Peroxidase; Receptor Tyrosine Kinase-like Orphan Receptors; Receptors, Calcium-Sensing; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Wnt Proteins; Wnt-5a Protein; Wnt3A Protein | 2013 |
Diet-induced obesity promotes colon tumor development in azoxymethane-treated mice.
Topics: Aberrant Crypt Foci; Adenoma; Animals; Azoxymethane; Colon; Colonic Neoplasms; Diet, High-Fat; Interferon-gamma; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Obesity; Risk Factors; Tumor Necrosis Factor-alpha | 2013 |
Prevention of familial adenomatous polyp development in APC min mice and azoxymethane-induced colon carcinogenesis in F344 Rats by ω-3 fatty acid rich perilla oil.
Topics: Aberrant Crypt Foci; Adenomatous Polyposis Coli; alpha-Linolenic Acid; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Colonic Neoplasms; Corn Oil; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Female; Intestinal Mucosa; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Plant Oils; Rats; Rats, Inbred F344 | 2013 |
Chemopreventive effects of PBI-Se, a selenium-containing analog of PBIT, on AOM-induced aberrant crypt foci in F344 rats.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Chemoprevention; Colonic Neoplasms; Cyclin D1; Humans; Interleukin-6; Interleukin-8; Male; Nitric Oxide Synthase Type II; Rats; Rats, Inbred F344; Selenium Compounds; Thiourea | 2013 |
Suppressive effect of RAS inhibitor manumycin A on aberrant crypt foci formation in the azoxymethane-induced rat colorectal carcinogenesis model.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Colorectal Neoplasms; Disease Models, Animal; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Farnesyltranstransferase; Genes, ras; Injections, Subcutaneous; Ki-67 Antigen; Mutation; Phosphorylation; Polyenes; Polyunsaturated Alkamides; ras Proteins; Rats; Rats, Inbred F344 | 2013 |
Role of anthocyanin-enriched purple-fleshed sweet potato p40 in colorectal cancer prevention.
Topics: Aberrant Crypt Foci; Animals; Anthocyanins; Antineoplastic Agents; Antioxidants; Azoxymethane; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Dietary Fiber; Epithelial Cells; Female; Glucosides; Humans; Immunohistochemistry; Ipomoea batatas; Mice; Phenols; Plant Extracts; Proliferating Cell Nuclear Antigen | 2013 |
Risk of colonic cancer is not higher in the obese Lep(ob) mouse model compared to lean littermates.
Topics: Aberrant Crypt Foci; Analysis of Variance; Animals; Azoxymethane; Colonic Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Random Allocation | 2013 |
Effects of dark chocolate on azoxymethane-induced colonic aberrant crypt foci.
Topics: Aberrant Crypt Foci; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Azoxymethane; Cacao; Candy; Carcinogens; Cell Proliferation; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Down-Regulation; Male; Plant Extracts; Polyphenols; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription Factor RelA | 2013 |
Pomegranate polyphenolics suppressed azoxymethane-induced colorectal aberrant crypt foci and inflammation: possible role of miR-126/VCAM-1 and miR-126/PI3K/AKT/mTOR.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Beverages; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; HT29 Cells; Humans; Inflammation; Lythraceae; Male; MicroRNAs; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinase; Polyphenols; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases; Vascular Cell Adhesion Molecule-1 | 2013 |
Nabag (Zizyphus spina-christi) extract prevents aberrant crypt foci development in colons of azoxymethane-treated rats by abrogating oxidative stress and inducing apoptosis.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Carcinogens; Caspase 3; Colon; Colonic Neoplasms; Fruit; Glutathione; Male; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Ziziphus | 2013 |
Grapefruit juice suppresses azoxymethane-induced colon aberrant crypt formation and induces antioxidant capacity in mice.
Topics: Aberrant Crypt Foci; Animals; Antioxidants; Apoptosis; Azoxymethane; Beverages; Carcinogens; Citrus paradisi; Colon; Female; Lipid Peroxidation; Mice; Micronucleus Tests; Phytotherapy | 2013 |
Chemoprevention of colonic aberrant crypt foci by Gynura procumbens in rats.
Topics: Aberrant Crypt Foci; Animals; Antioxidants; Asteraceae; Azoxymethane; Carcinogens; Chemoprevention; Colon; Colorectal Neoplasms; Female; Glutathione Transferase; Male; Malondialdehyde; Phenols; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Toxicity Tests, Acute | 2014 |
Chemopreventive evaluation of a Schiff base derived copper (II) complex against azoxymethane-induced colorectal cancer in rats.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Blood Chemical Analysis; Body Weight; Carcinogens; Chemoprevention; Colorectal Neoplasms; Copper; Disease Models, Animal; Female; Kidney; Liver; Male; Oxidation-Reduction; Proliferating Cell Nuclear Antigen; Rats; Schiff Bases; Toxicity Tests, Acute | 2014 |
Enhanced chemopreventive effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer.
Topics: Aberrant Crypt Foci; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Colon; Colorectal Neoplasms; Dinoprostone; Male; Mice; Naproxen; Protective Agents; Rats; Thromboxane B2 | 2014 |
Evaluation of chemopreventive effects of Acanthus ilicifolius against azoxymethane-induced aberrant Crypt Foci in the rat colon.
Topics: Aberrant Crypt Foci; Acanthaceae; Animals; Anticarcinogenic Agents; Azoxymethane; Colonic Neoplasms; Female; Male; Plant Extracts; Rats; Rats, Sprague-Dawley | 2014 |
A non-digestible fraction of the common bean (Phaseolus vulgaris L.) induces cell cycle arrest and apoptosis during early carcinogenesis.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Carcinogenesis; Cell Cycle Checkpoints; Cell Line, Tumor; Colon; Colonic Neoplasms; Cooking; Dietary Carbohydrates; Dietary Fiber; Dietary Proteins; Digestion; Flavonoids; Male; Phaseolus; Plant Extracts; Rats; Rats, Sprague-Dawley | 2014 |
Chemopreventive efficacy of Andrographis paniculata on azoxymethane-induced aberrant colon crypt foci in vivo.
Topics: Aberrant Crypt Foci; Andrographis; Animals; Anticarcinogenic Agents; Antioxidants; Azoxymethane; beta Catenin; Cell Line, Tumor; Colon; Colorectal Neoplasms; Female; Flavonoids; Humans; Malondialdehyde; Nitric Oxide; Phenol; Plant Extracts; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tissue Distribution | 2014 |
Dietary aloe vera gel powder and extract inhibit azoxymethane- induced colorectal aberrant crypt foci in mice fed a high- fat diet.
Topics: Aberrant Crypt Foci; Aloe; Animals; Azoxymethane; Blotting, Western; Carcinogens; Colorectal Neoplasms; Cytochrome P-450 CYP2E1; Diet, High-Fat; Glutathione Transferase; Humans; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Powders; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2015 |
Oral concentrated grape juice suppresses expression of NF-kappa B, TNF-α and iNOS in experimentally induced colorectal carcinogenesis in Wistar rats.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Carcinogens; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Gene Expression Regulation, Neoplastic; Humans; Male; NF-kappa B; Phytotherapy; Plant Extracts; Precancerous Conditions; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vitis | 2015 |
Unpolished Thai rice prevents ACF formation and dysplastic progression in AOM-induced rats and induces apoptosis through redox alteration in CaCo-2 cells.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Caco-2 Cells; Carcinogens; Cell Proliferation; Colonic Neoplasms; Diet; Disease Progression; Flow Cytometry; Humans; Male; Oryza; Oxidation-Reduction; Oxidative Stress; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 2015 |
The chemopotential effect of Annona muricata leaves against azoxymethane-induced colonic aberrant crypt foci in rats and the apoptotic effect of Acetogenin Annomuricin E in HT-29 cells: a bioassay-guided approach.
Topics: Aberrant Crypt Foci; Animals; Annona; Apoptosis; Azoxymethane; bcl-2-Associated X Protein; Caspase 3; Caspase 7; Caspase 9; Cell Proliferation; Colon; Cytochromes c; Down-Regulation; Furans; G1 Phase Cell Cycle Checkpoints; HT29 Cells; Humans; Immunohistochemistry; Lactones; Lipid Peroxidation; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria; Plant Extracts; Plant Leaves; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Up-Regulation | 2015 |
Inhibition of Azoxymethane-induced Colorectal Aberrant Crypt Foci in Mice Fed a High-fat Diet by Pleurotus eryngii (Eringi) and Hypsizygus marmoreus (Bunashimeji).
Topics: Aberrant Crypt Foci; Agaricales; Animals; Azoxymethane; Body Weight; Carcinogens; Cholesterol; Colorectal Neoplasms; Diet, High-Fat; Immunoenzyme Techniques; Male; Mice; Mice, Inbred C57BL; Powders; Triglycerides | 2015 |
Chemoprevention of Colonic Aberrant Crypt Foci by Novel Schiff Based Dichlorido(4-Methoxy-2-{[2-(Piperazin-4-Ium-1-Yl)Ethyl]Iminomethyl}Phenolate)Cd Complex in Azoxymethane-Induced Colorectal Cancer in Rats.
Topics: Aberrant Crypt Foci; Animals; Antineoplastic Agents; Azoxymethane; Carcinogenesis; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Male; Rats; Rats, Sprague-Dawley; Schiff Bases; Treatment Outcome | 2015 |
The chemopreventive potential of Curcuma purpurascens rhizome in reducing azoxymethane-induced aberrant crypt foci in rats.
Topics: Aberrant Crypt Foci; Animals; Antioxidants; Apoptosis; Azoxymethane; Chemoprevention; Colonic Neoplasms; Curcuma; Dose-Response Relationship, Drug; Fluorouracil; Male; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome | 2015 |
Nexrutine inhibits azoxymethane-induced colonic aberrant crypt formation in rat colon and induced apoptotic cell death in colon adenocarcinoma cells.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; Gene Expression Regulation, Neoplastic; Humans; Male; Nitric Oxide Synthase Type II; Plant Extracts; Rats; Xenograft Model Antitumor Assays | 2016 |
Dietary Ziziphus jujuba Fruit Influence on Aberrant Crypt Formation and Blood Cells in Colitis-Associated Colorectal Cancer in Mice.
Topics: Aberrant Crypt Foci; Adenocarcinoma; Animals; Azoxymethane; Carcinogenesis; Chemoprevention; Colitis; Colon; Colorectal Neoplasms; Dextran Sulfate; Diet; Dietary Supplements; Disease Progression; Hyperplasia; Leukocyte Count; Leukocytes; Male; Mice; Mice, Inbred C57BL; Plant Preparations; Ziziphus | 2015 |
Colon Cancer Chemoprevention by Sage Tea Drinking: Decreased DNA Damage and Cell Proliferation.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Cell Proliferation; Chemoprevention; Colorectal Neoplasms; Cytochrome P-450 CYP2E1; DNA Damage; Female; Plant Extracts; Rats; Rats, Inbred F344; Salvia officinalis; Teas, Herbal | 2016 |
Suggestive evidence for the induction of colonic aberrant crypts in mice fed sodium nitrite.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Colorectal Neoplasms; Female; Hemin; Mice; Sodium Nitrite | 2016 |
Hydrolysed inulin alleviates the azoxymethane-induced preneoplastic aberrant crypt foci by altering selected intestinal microbiota in Sprague-Dawley rats.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Bacteria; Bacterial Load; Biomass; Colon; Colonic Neoplasms; Disease Models, Animal; Gastrointestinal Microbiome; Hydrolysis; Inulin; Male; Rats, Sprague-Dawley; Time Factors | 2016 |
Brewers' rice attenuated aberrant crypt foci developing in colon of azoxymethane-treated rats.
Topics: Aberrant Crypt Foci; Alanine Transaminase; Animals; Azoxymethane; Body Weight; Colorectal Neoplasms; Male; Oryza; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2016 |
Hypocholesterolemic and Anticarcinogenic Effect of Vicia faba Protein Hydrolyzates.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Antioxidants; Azoxymethane; Cholesterol, Dietary; Colorectal Neoplasms; Diet; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; Plant Extracts; Protein Hydrolysates; Vicia faba | 2016 |
Unpolished Thai Rice Prevents Aberrant Crypt Foci Formation through the Invovement of ?catenin and COX2 Expression in AzoxymethaneTreated Rats.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Biomarkers; Catenins; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase 2; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-6; Male; Oryza; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Thailand | 2016 |
Rapidly cycling Lgr5
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; beta Catenin; Carcinogenesis; Carcinogens; Cell Cycle; Cell Differentiation; Cell Nucleus; Chemoprevention; Colon; Colonic Neoplasms; Curcumin; Diet; DNA Breaks, Double-Stranded; DNA Modification Methylases; DNA Repair Enzymes; Fatty Acids, Omega-3; Fish Oils; Green Fluorescent Proteins; Mice; Receptors, G-Protein-Coupled; Regeneration; Risk Factors; Signal Transduction; Stem Cells; Subcellular Fractions; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2016 |
Plum polyphenols inhibit colorectal aberrant crypt foci formation in rats: potential role of the miR-143/protein kinase B/mammalian target of rapamycin axis.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Cell Proliferation; Chlorogenic Acid; Colon; Colonic Neoplasms; Diet; Inflammation Mediators; Intestinal Mucosa; Male; MicroRNAs; Phosphorylation; Plant Extracts; Polyphenols; Proto-Oncogene Proteins c-akt; Prunus domestica; Quinic Acid; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases | 2016 |
Genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Exome Sequencing; Genetic Variation; Humans; Male; Mice, Inbred C57BL; Mutation; Neoplasms, Experimental | 2017 |
Optimization of visibility and quantification of aberrant crypt foci in colonic mucosa in Wistar rats.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Intestinal Mucosa; Microscopy; Rats; Rats, Wistar | 2010 |
Chemoprevention of colonic tumorigenesis by dietary hydroxylated polymethoxyflavones in azoxymethane-treated mice.
Topics: Aberrant Crypt Foci; Adenoma; Animals; Apoptosis; Azoxymethane; Carcinogens; Citrus sinensis; Colon; Colonic Neoplasms; Cyclooxygenase 2; Diet; Flavones; Fruit; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Inbred ICR; Nitric Oxide Synthase Type II; Random Allocation; RNA, Messenger; Signal Transduction; Time Factors | 2011 |
Immunomodulatory effects of Withania somnifera on azoxymethane induced experimental colon cancer in mice.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Colon; Colonic Neoplasms; Immunocompetence; Immunoglobulins; Immunomodulation; Mice; Neoplasms, Experimental; Plant Extracts; Plant Roots; Withania | 2010 |
Kenaf seed supercritical fluid extract reduces aberrant crypt foci formation in azoxymethane-induced rats.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Hibiscus; Male; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Seeds | 2012 |
High susceptibility to azoxymethane-induced colorectal carcinogenesis in obese KK-Ay mice.
Topics: Aberrant Crypt Foci; Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Disease Models, Animal; Disease Susceptibility; Incidence; Mice; Mice, Inbred C57BL; Mice, Obese; Receptors, Leptin | 2011 |
Dietary acrylamide does not increase colon aberrant crypt foci formation in male F344 rats.
Topics: Aberrant Crypt Foci; Acrylamide; Animals; Azoxymethane; Biomarkers, Tumor; Carcinogens; Caspase 9; Colon; Colorectal Neoplasms; Corn Oil; Drug Interactions; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344 | 2011 |
Disruption of the mouse protein tyrosine kinase 6 gene prevents STAT3 activation and confers resistance to azoxymethane.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Carcinogens; Cell Proliferation; Colon; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; HCT116 Cells; Humans; Immunoblotting; Immunohistochemistry; Mice; Mice, Knockout; Neoplasm Proteins; Phosphorylation; Protein-Tyrosine Kinases; RNA Interference; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Time Factors | 2011 |
Dietary folate protects against azoxymethane-induced aberrant crypt foci development and oxidative stress in rat colon.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Dietary Supplements; Dose-Response Relationship, Drug; Folic Acid; Glutathione; Male; Oxidative Stress; Rats | 2011 |
Microsomal prostaglandin E synthase-1 is involved in multiple steps of colon carcinogenesis.
Topics: Aberrant Crypt Foci; Adenocarcinoma; Animals; Azoxymethane; beta Catenin; Carcinogens; Cell Transformation, Neoplastic; Coculture Techniques; Colonic Neoplasms; Colonic Polyps; Cytokines; Gene Expression Profiling; Intramolecular Oxidoreductases; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microsomes; Neoplasm Transplantation; Prostaglandin-E Synthases; Prostaglandins | 2012 |
Effect of a hyperlipidic diet rich in omegas 3, 6 and 9 on aberrant crypt formation in rat colonic mucosa.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Body Weight; Carcinogens; Colon; Colorectal Neoplasms; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Intestinal Mucosa; Male; Random Allocation; Rats; Rats, Wistar | 2012 |
Induction of colonic aberrant crypts in mice by feeding apparent N-nitroso compounds derived from hot dogs.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Feces; Female; Food Handling; Meat Products; Mice; Nitrosation; Nitroso Compounds; Sodium Nitrite | 2012 |
Study of 5-hydroxymethylfurfural and its metabolite 5-sulfooxymethylfurfural on induction of colonic aberrant crypt foci in wild-type mice and transgenic mice expressing human sulfotransferases 1A1 and 1A2.
Topics: Aberrant Crypt Foci; Animals; Arylsulfotransferase; Azoxymethane; Colon; Disease Models, Animal; Female; Furaldehyde; Gene Expression Regulation; Intestinal Mucosa; Kidney; Liver; Male; Mice; Mice, Inbred Strains; Mice, Transgenic | 2012 |
Effect of dietary fibre of barley variety 'Rihane' on azoxymethane-induced aberrant crypt foci development and on colonic microbiota diversity in rats.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Bifidobacterium; Carcinogens; Colon; Colorectal Neoplasms; Dietary Fiber; Disease Models, Animal; Enterobacteriaceae; Gastrointestinal Contents; Hordeum; Hydrogen-Ion Concentration; Intestinal Mucosa; Male; Phylogeny; Prebiotics; Random Allocation; Rats; Rats, Wistar; Seeds; Tunisia | 2012 |
P53 gene mutation increases progastrin dependent colonic proliferation and colon cancer formation in mice.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Disease Models, Animal; Female; Gastrins; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Protein Precursors; Tumor Suppressor Protein p53 | 2012 |
Regulation of colon gene expression by vitamin B6 supplementation.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; CD8 Antigens; Cell Proliferation; Chemokine CCL8; Colon; Colonic Neoplasms; Dietary Supplements; Down-Regulation; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Inbred ICR; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Vitamin B 6 | 2012 |
Genistein, a soya isoflavone, prevents azoxymethane-induced up-regulation of WNT/β-catenin signalling and reduces colon pre-neoplasia in rats.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Biomarkers; Carcinogens; Colon, Descending; Colonic Neoplasms; Cyclin D1; Disease Models, Animal; Down-Regulation; Female; Genistein; Lactation; Male; Maternal Nutritional Physiological Phenomena; Precancerous Conditions; Pregnancy; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley; Soybean Proteins; Wnt Signaling Pathway | 2013 |
Effect of luteolin on the levels of glycoproteins during azoxymethane-induced colon carcinogenesis in mice.
Topics: Aberrant Crypt Foci; Analysis of Variance; Animals; Anticarcinogenic Agents; Azoxymethane; Colon; Colonic Neoplasms; Fucose; Glycoconjugates; Glycoproteins; Hexosamines; Hexoses; Lipid Peroxidation; Luteolin; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Mucins; Mucoproteins; N-Acetylneuraminic Acid; Protein Carbonylation | 2012 |
Red strain oryza sativa-unpolished thai rice prevents oxidative stress and colorectal aberrant crypt foci formation in rats.
Topics: Aberrant Crypt Foci; Animals; Antioxidants; Azoxymethane; Benzothiazoles; Biphenyl Compounds; Colorectal Neoplasms; Male; Malondialdehyde; Oryza; Oxidative Stress; Phytotherapy; Picrates; Plant Extracts; Rats; Rats, Sprague-Dawley; Sulfonic Acids; Thiazoles | 2012 |
Pomegranate (Punica granatum) peel extract efficacy as a dietary antioxidant against azoxymethane-induced colon cancer in rat.
Topics: Aberrant Crypt Foci; Animals; Antioxidants; Azoxymethane; Body Weight; Carcinogens; Colonic Neoplasms; Humans; Intestinal Mucosa; Lythraceae; Male; Oxidative Stress; Phytotherapy; Prognosis; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 2012 |
Suppressive effect of pioglitazone, a PPAR gamma ligand, on azoxymethane-induced colon aberrant crypt foci in KK-Ay mice.
Topics: Aberrant Crypt Foci; Adipokines; Animals; Azoxymethane; Biomarkers; Carcinogens; Colorectal Neoplasms; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Hypoglycemic Agents; Immunoenzyme Techniques; Insulin; Intra-Abdominal Fat; Leptin; Lipids; Mice; Mice, Inbred C57BL; Obesity; Pioglitazone; PPAR gamma; Thiazolidinediones | 2012 |
Vanillin differentially affects azoxymethane-injected rat colon carcinogenesis and gene expression.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Benzaldehydes; Cell Cycle; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; DNA Mismatch Repair; Gene Expression; Male; Mutation; Rats; Rats, Sprague-Dawley | 2012 |
A novel NSAID derivative, phospho-ibuprofen, prevents AOM-induced colon cancer in rats.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Ibuprofen; Neoplasms, Experimental; NF-kappa B; Organophosphates; Rats | 2013 |
Effective suppression of azoxymethane-induced aberrant crypt foci formation in mice with citrus peel flavonoids.
Topics: Aberrant Crypt Foci; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Azoxymethane; Citrus; Colonic Neoplasms; Cyclooxygenase 2; Flavonoids; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred ICR; Nitric Oxide Synthase Type II; Ornithine Decarboxylase; Plant Extracts; Vascular Endothelial Growth Factor A | 2013 |
Effects of a water-soluble extract of Ganoderma lucidum mycelia on aberrant crypt foci induced by azoxymethane and small-intestinal injury by 5-FU in F344 rats.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Colonic Neoplasms; Culture Media; Fluorouracil; Intestinal Mucosa; Intestine, Small; Male; Mycelium; Rats; Rats, Inbred F344; Reishi; Water | 2013 |
Characterization of PPAR dual ligand MCC-555 in AOM-induced colorectal tumorigenesis.
Topics: Aberrant Crypt Foci; Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred Strains; Mitosis; Mucin-2; PPAR gamma; Thiazolidinediones | 2013 |