Page last updated: 2024-08-21

azomycin and Trypanosomiasis, African

azomycin has been researched along with Trypanosomiasis, African in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (26.42)	18.7374
1990's	6 (11.32)	18.2507
2000's	4 (7.55)	29.6817
2010's	22 (41.51)	24.3611
2020's	7 (13.21)	2.80

Authors

Authors	Studies
Strub-Wourgaft, N; Tarral, A; Valverde Mordt, O	1
Bardonneau, C; Bernhard, S; Blesson, S; Delhomme, S; Fina Lubaki, JP; Ilunga Wa Kyhi, M; Kande Betu Kumesu, V; Kaninda Badibabi, L; Kasongo Bonama, A; Kavunga Lukula, P; Kuziena Mindele, W; Lumbala, C; Lumeya Vuvu, S; Mahenzi Mbembo, H; Mandula Mokenge, G; Mutombo Kalonji, W; Nganzobo Ngima, P; Ngolo Tete, D; Scherrer, B; Simon, F; Strub-Wourgaft, N; Tarral, A; Valverde Mordt, O	1
Gudmundsson, KSS; Helleberg, BB; Helleberg, M; Kurtzhals, JAL	1
Bayão, TS; Cupertino, MDC; Gomes, AP; Siqueira-Batista, R	1
Fairlamb, AH	1
Akl, EA; Barrett, MP; Bergman, H; Chappuis, F; Erphas, O; Franco, JR; Kadima Ebeja, A; Kazumba, L; Lejon, V; Lindner, AK; Mwamba, E; Priotto, G; Seixas, J; Simarro, P; Villanueva, G	1
Kaiser, M; Mäser, P	1
Dattani, A; Drammeh, I; Mahmood, A; Rahman, M; Szular, J; Wilkinson, SR	1
Akwaso Masa, F; Bardonneau, C; Bernhard, S; Blesson, S; Botalema Bolengi, F; Delhomme, S; Kande Betu Ku Mesu, V; Kapongo Tshilumbwa, S; Lumbala, C; Lumeya Vuvu, S; Mahenzi Mbembo, H; Mayala Malu, T; Mpia Moke, C; Mpoyi Muamba Nzambi, D; Mudji E'kitiak, J; Mukendi Ilunga, M; Mutombo Kalonji, W; Ngolo Tete, D; Nkieri Matsho, M; Scherrer, B; Simon, F; Strub-Wourgaft, N; Tarral, A; Valverde Mordt, O	1
Alavijeh, MS; Burrell-Saward, H; Croft, SL; de LaFlor, R; Harris, AJ; Sallam, H; Ward, TH	1
Maxmen, A	2
Badibabi, LK; Bardonneau, C; Bernhard, S; Blesson, S; Bonama, AK; Dama, FR; Delhomme, S; Heradi, JA; Ilunga, M; Kalonji, WM; Kuziena, W; Lubaki, JF; Lukula, PK; Lumbala, C; Mandula, G; Mbembo, HM; Mesu, VKBK; Mordt, OV; Ngima, PN; Scherrer, B; Simon, F; Solomo, JLL; Strub-Wourgaft, N; Tarral, A; Tete, DN; Vuvu, SL	1
Bacchi, CJ; Braillard, S; Chatelain, E; Denny, WA; Gaukel, E; Launay, D; Maes, L; Marshall, AJ; Mowbray, CE; Thompson, AM; Wring, SA; Yarlett, N	1
Pollastri, MP	1
Chappuis, F	1
Deeks, ED	1
Cavaleri, M; Harvey Allchurch, M; Nagercoil, N; Nambasa, V; Ntamabyaliro, N; Pelfrene, E; Ventura, FV	1
Blesson, S; Bray, MA; Evène, E; Felices, M; Gualano, V; Hovsepian, L; Mordt, OV; Sassella, D; Strub-Wourgaft, N; Tarral, A; Torreele, E	1
Ardiot, C; Blesson, S; Bompart, F; Bonnin, Y; Coleman, CH; Colonna, P; Dhai, A; Ecuru, J; Edielu, A; Hervé, C; Hirsch, F; Kouyaté, B; Mamzer-Bruneel, MF; Maoundé, D; Martinent, E; Ntsiba, H; Pelé, G; Quéva, G; Reinmund, MC; Sarr, SC; Sepou, A; Strub-Wourgaft, N; Tarral, A; Tetimian, D; Valverde, O; Van Nieuwenhove, S	1
Barrett, MP	1
Bourdin Trunz, B; Bray, MA; Brun, R; Kaiser, M; Mazué, G; Pécoul, B; Torreele, E; Tweats, D	1
Brun, R; Jędrysiak, R; Kaiser, M; Suwiński, J; Torreele, E; Trunz, BB; Tweats, D	1
Bot, C; Hall, BS; Kelly, JM; Wilkinson, SR	1
Barrett, MP; Brun, R; Don, R; Jacobs, RT; Wang, MZ	1
Bourdin Trunz, B; Bray, MA; Brun, R; Cal, M; Kaiser, M; Torreele, E	1
Hall, BS; Wilkinson, SR	1
Bourdin Trunz, B; Torreele, E; Tweats, D	1
Barrett, MP; Croft, SL	1
Bouteille, B; Dumas, M	3
Jennings, FW; Miller, BM; Murray, PK; Urquhart, GM	3
Jennings, FW; Urquhart, GM	1
Hochmann, A; Lambert, PH; Poltera, AA	1
Tchalim, TK	1
Jennings, FW	3
Atouguia, JM; Jennings, FW; Murray, M	1
Barrett, MP; Chauvière, G; Fairlamb, AH; Perié, J; Rousseau, B	1
de Koning, HP	1
Jamieson, WB; Ross, WJ	2
Adams, JH; Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M	1
Bouteille, B; Darde, ML; Pestre-Alexandre, M	1
Gutteridge, WE	1
Felix, H; Kombila, MY; Richard-Lenoble, D	1
Bouteille, B; Breton, JC; Catanzano, G; Darde, ML; Dumas, M; Munoz, M; Nicolas, JA; Pestre-Alexandre, M	1
Röttcher, D; Zweygarth, E	2

Reviews

10 review(s) available for azomycin and Trypanosomiasis, African

Article	Year
Fexinidazole for the treatment of human African trypanosomiasis. Drugs of today (Barcelona, Spain : 1998), 2019, Volume: 55, Issue:11 Topics: Humans; Nitroimidazoles; Trypanocidal Agents; Trypanosomiasis, African	2019
Fexinidazole: First Global Approval. Drugs, 2019, Volume: 79, Issue:2 Topics: Administration, Oral; Drug Approval; Humans; Nitroimidazoles; Treatment Outcome; Trypanocidal Agents; Trypanosomiasis, African	2019
Potential new drugs for human African trypanosomiasis: some progress at last. Current opinion in infectious diseases, 2010, Volume: 23, Issue:6 Topics: Animals; Benzamides; Boron Compounds; Drug Discovery; Drug Resistance; Drug Therapy, Combination; Eflornithine; Humans; Melarsoprol; Mice; Nifurtimox; Nitroimidazoles; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2010
Trypanocidal activity of nitroaromatic prodrugs: current treatments and future perspectives. Current topics in medicinal chemistry, 2011, Volume: 11, Issue:16 Topics: Africa; Animals; Benzamides; Chagas Disease; Humans; Insect Vectors; Latin America; Nifurtimox; Nitro Compounds; Nitroimidazoles; Nitroreductases; Phosphoramide Mustards; Prodrugs; Protozoan Proteins; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi; Trypanosomiasis, African	2011
Development of novel drugs for human African trypanosomiasis. Future microbiology, 2011, Volume: 6, Issue:6 Topics: Animals; Antiprotozoal Agents; Benzoxazoles; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Haplorhini; Humans; Mice; Neglected Diseases; Nitroimidazoles; Trypanosoma brucei brucei; Trypanosomiasis, African	2011
Management of trypanosomiasis and leishmaniasis. British medical bulletin, 2012, Volume: 104 Topics: Administration, Oral; Africa; Amphotericin B; Antiprotozoal Agents; Benzamides; Boron Compounds; Chagas Disease; Drug Therapy, Combination; Humans; India; Leishmaniasis; Nitroimidazoles; Pentamidine; Triazoles; Trypanosomiasis, African	2012
[Human African trypanosomiasis: present and future treatment ]. Bulletin de la Societe de pathologie exotique (1990), 2002, Volume: 95, Issue:5 Topics: Adenosylmethionine Decarboxylase; Blood-Brain Barrier; Drug Costs; Drug Evaluation, Preclinical; Drug Industry; Forecasting; Global Health; Health Policy; Humans; Myristic Acid; Nitroimidazoles; Thiadiazoles; Trypanocidal Agents; Trypanosomiasis, African; Vaccination	2002
Combination chemotherapy of CNS trypanosomiasis. Acta tropica, 1993, Volume: 54, Issue:3-4 Topics: Arsenicals; Central Nervous System Diseases; Drug Therapy, Combination; Humans; Melarsoprol; Nitroimidazoles; Trypanocidal Agents; Trypanosomiasis, African	1993
Transporters in African trypanosomes: role in drug action and resistance. International journal for parasitology, 2001, May-01, Volume: 31, Issue:5-6 Topics: Africa South of the Sahara; Animals; Arsenicals; Biological Transport; Eflornithine; Humans; Nitroimidazoles; Pentamidine; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African	2001
Existing chemotherapy and its limitations. British medical bulletin, 1985, Volume: 41, Issue:2 Topics: Chagas Disease; Gentian Violet; Humans; Melarsoprol; Nifurtimox; Nitroimidazoles; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African	1985

Trials

3 trial(s) available for azomycin and Trypanosomiasis, African

Article	Year
Safety and efficacy of oral fexinidazole in children with gambiense human African trypanosomiasis: a multicentre, single-arm, open-label, phase 2-3 trial. The Lancet. Global health, 2022, Volume: 10, Issue:11 Topics: Administration, Oral; Child; Humans; Nitroimidazoles; Tablets; Treatment Outcome; Trypanocidal Agents; Trypanosomiasis, African	2022
Oral fexinidazole for late-stage African Trypanosoma brucei gambiense trypanosomiasis: a pivotal multicentre, randomised, non-inferiority trial. Lancet (London, England), 2018, 01-13, Volume: 391, Issue:10116 Topics: Administration, Oral; Adult; Democratic Republic of the Congo; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nifurtimox; Nitroimidazoles; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African	2018
Determination of an optimal dosing regimen for fexinidazole, a novel oral drug for the treatment of human African trypanosomiasis: first-in-human studies. Clinical pharmacokinetics, 2014, Volume: 53, Issue:6 Topics: Administration, Oral; Adolescent; Adult; Biological Availability; Cross-Over Studies; Dietary Fats; Dose-Response Relationship, Drug; Double-Blind Method; Food-Drug Interactions; Humans; Male; Middle Aged; Nitroimidazoles; Prodrugs; Suspensions; Tablets; Trypanocidal Agents; Trypanosomiasis, African; Young Adult	2014

Other Studies

40 other study(ies) available for azomycin and Trypanosomiasis, African

Article	Year
Development and Introduction of Fexinidazole into the Global Human African Trypanosomiasis Program. The American journal of tropical medicine and hygiene, 2022, 05-11, Volume: 106, Issue:5_Suppl Topics: Administration, Oral; Animals; Humans; Nitroimidazoles; Trypanosoma brucei gambiense; Trypanosomiasis, African	2022
Second stage human African Trypanosomiasis with Trypanosoma brucei rhodesiense treated with fexinidazole. The Lancet. Infectious diseases, 2023, Volume: 23, Issue:11 Topics: Animals; Humans; Nitroimidazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2023
Fexinidazole and Human African Trypanosomiasis: good news for this important neglected tropical disease. Revista da Sociedade Brasileira de Medicina Tropical, 2019, Volume: 52 Topics: Humans; Neglected Diseases; Nitroimidazoles; Trypanocidal Agents; Trypanosomiasis, African	2019
New WHO guidelines for treatment of gambiense human African trypanosomiasis including fexinidazole: substantial changes for clinical practice. The Lancet. Infectious diseases, 2020, Volume: 20, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiprotozoal Agents; Child; Child, Preschool; Eflornithine; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Nifurtimox; Nitroimidazoles; Practice Guidelines as Topic; Trypanosoma brucei gambiense; Trypanosomiasis, African; World Health Organization; Young Adult	2020
In Vitro Drug Efficacy Testing Against Trypanosoma brucei. Methods in molecular biology (Clifton, N.J.), 2020, Volume: 2116 Topics: Calorimetry; Drug Evaluation, Preclinical; Humans; Life Cycle Stages; Nitroimidazoles; Parasitic Sensitivity Tests; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African	2020
Unraveling the antitrypanosomal mechanism of benznidazole and related 2-nitroimidazoles: From prodrug activation to DNA damage. Molecular microbiology, 2021, Volume: 116, Issue:2 Topics: Activation, Metabolic; DNA Breaks, Double-Stranded; DNA Repair; Genome, Protozoan; Nitroimidazoles; Nitroreductases; Prodrugs; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2021
Oral fexinidazole for stage 1 or early stage 2 African Trypanosoma brucei gambiense trypanosomiasis: a prospective, multicentre, open-label, cohort study. The Lancet. Global health, 2021, Volume: 9, Issue:7 Topics: Administration, Oral; Adolescent; Adult; Aged; Democratic Republic of the Congo; Female; Humans; Male; Middle Aged; Nitroimidazoles; Prospective Studies; Severity of Illness Index; Treatment Outcome; Trypanosoma brucei gambiense; Trypanosomiasis, African; Young Adult	2021
Dose-dependent effect and pharmacokinetics of fexinidazole and its metabolites in a mouse model of human African trypanosomiasis. International journal of antimicrobial agents, 2017, Volume: 50, Issue:2 Topics: Animals; Antiprotozoal Agents; Cerebral Cortex; Cerebrospinal Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hippocampus; Luminescent Measurements; Mice; Nitroimidazoles; Plasma; Treatment Outcome; Trypanosoma; Trypanosomiasis, African; Whole Body Imaging	2017
Sleeping sickness can now be cured with pills. Nature, 2017, 10-18, Volume: 550, Issue:7677 Topics: Administration, Oral; Clinical Trials, Phase III as Topic; Drug Approval; Drug Combinations; Humans; Nitroimidazoles; Trypanosomiasis, African	2017
Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides. Bioorganic & medicinal chemistry letters, 2018, 01-15, Volume: 28, Issue:2 Topics: Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mice; Molecular Structure; Nitroimidazoles; Small Molecule Libraries; Structure-Activity Relationship; Trypanosomiasis, African	2018
Fexinidazole: A New Drug for African Sleeping Sickness on the Horizon. Trends in parasitology, 2018, Volume: 34, Issue:3 Topics: Clinical Trials as Topic; Drug Approval; Humans; Nitroimidazoles; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African	2018
Oral fexinidazole for human African trypanosomiasis. Lancet (London, England), 2018, 01-13, Volume: 391, Issue:10116 Topics: Administration, Oral; Animals; Humans; Nitroimidazoles; Trypanosomiasis, African	2018
The European Medicines Agency's scientific opinion on oral fexinidazole for human African trypanosomiasis. PLoS neglected tropical diseases, 2019, Volume: 13, Issue:6 Topics: Administration, Oral; Drug Approval; Drug-Related Side Effects and Adverse Reactions; Humans; Nitroimidazoles; Treatment Outcome; Trypanocidal Agents; Trypanosomiasis, African	2019
Improving the Quality of Host Country Ethical Oversight of International Research: The Use of a Collaborative 'Pre-Review' Mechanism for a Study of Fexinidazole for Human African Trypanosomiasis. Developing world bioethics, 2015, Volume: 15, Issue:3 Topics: Antiprotozoal Agents; Biomedical Research; Developing Countries; Ethical Review; Humans; International Cooperation; Nitroimidazoles; Trypanosomiasis, African	2015
Busting the billion-dollar myth: how to slash the cost of drug development. Nature, 2016, 08-25, Volume: 536, Issue:7617 Topics: Africa; Amodiaquine; Anti-Bacterial Agents; Artemisinins; Benzamides; Boron Compounds; Child; Clinical Trials as Topic; Cooperative Behavior; Developed Countries; Developing Countries; Drug Approval; Drug Combinations; Drug Costs; Drug Discovery; Drug Industry; Drug Repositioning; Drug Resistance, Microbial; Female; Humans; Malaria; Neglected Diseases; Negotiating; Nitroimidazoles; Organizations, Nonprofit; Sample Size; Trypanosomiasis, African; World Health Organization	2016
Fexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness. PLoS neglected tropical diseases, 2010, Dec-21, Volume: 4, Issue:12 Topics: Administration, Oral; Animals; Antiprotozoal Agents; Disease Models, Animal; Dogs; Female; Inhibitory Concentration 50; Mice; Nitroimidazoles; Parasitic Sensitivity Tests; Rats; Treatment Outcome; Trypanosomiasis, African	2010
1-Aryl-4-nitro-1H-imidazoles, a new promising series for the treatment of human African trypanosomiasis. European journal of medicinal chemistry, 2011, Volume: 46, Issue:5 Topics: Animals; Antiprotozoal Agents; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Leukocytes, Mononuclear; Mice; Molecular Structure; Mutagenicity Tests; Nitroimidazoles; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Trypanosomiasis, African	2011
Antitrypanosomal activity of fexinidazole, a new oral nitroimidazole drug candidate for treatment of sleeping sickness. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:12 Topics: Animals; Female; Humans; Mice; Nitroimidazoles; Parasitic Sensitivity Tests; Safrole; Sulfones; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2011
Activation of benznidazole by trypanosomal type I nitroreductases results in glyoxal formation. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1 Topics: Biotransformation; Chagas Disease; Chromatography, Liquid; DNA Damage; Glyoxal; Guanosine; Humans; Hydroxylamine; Imidazoles; Kinetics; Mass Spectrometry; NAD; Nitroimidazoles; Nitroreductases; Prodrugs; Protozoan Proteins; Spectrophotometry; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi; Trypanosomiasis, African	2012
Genotoxicity profile of fexinidazole--a drug candidate in clinical development for human African trypanomiasis (sleeping sickness). Mutagenesis, 2012, Volume: 27, Issue:5 Topics: Animals; Bacteria; Bone Marrow Cells; Hepatocytes; Humans; Leukocytes, Mononuclear; Male; Mice; Micronucleus Tests; Mutagenicity Tests; Mutagens; Nitroimidazoles; Nitroreductases; Rats; Trypanocidal Agents; Trypanosomiasis, African	2012
The use of 2-substituted 5-nitroimidazoles in the treatment of chronic murine Trypanosoma brucei infections with central nervous system involvement. Zeitschrift fur Parasitenkunde (Berlin, Germany), 1984, Volume: 70, Issue:6 Topics: Animals; Antiprotozoal Agents; Brain; Chronic Disease; Drug Therapy, Combination; Female; Mice; Mice, Inbred Strains; Nitroimidazoles; Rodent Diseases; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1984
The use of the 2 substituted 5-nitroimidazole, Fexinidazole (Hoe 239) in the treatment of chronic T. brucei infections in mice. Zeitschrift fur Parasitenkunde (Berlin, Germany), 1983, Volume: 69, Issue:5 Topics: Animals; Antiprotozoal Agents; Chronic Disease; Diminazene; Drug Therapy, Combination; Female; Mice; Mice, Inbred Strains; Nitroimidazoles; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1983
Treatment with suramin and 2-substituted 5-nitroimidazoles of chronic murine Trypanosoma brucei infections with central nervous system involvement. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1983, Volume: 77, Issue:5 Topics: Animals; Antiprotozoal Agents; Cattle; Central Nervous System Diseases; Drug Therapy, Combination; Female; Mice; Nitroimidazoles; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African	1983
Trypanosoma brucei brucei: the response to Melarsoprol in mice with cerebral trypanosomiasis. An immunopathological study. Clinical and experimental immunology, 1981, Volume: 46, Issue:2 Topics: Animals; Antigen-Antibody Complex; Arsenicals; Brain; Brain Diseases; Chloroquine; Fluorescent Antibody Technique; Injections, Intraperitoneal; Injections, Intravenous; Melarsoprol; Mice; Nitroimidazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1981
[Prophylactic and curative action of Ridzol-S and Ronidazole in experimental trypanosomiasis caused by Trypanosoma brucei et T. evansi]. Annales de la Societe belge de medecine tropicale, 1980, Volume: 60, Issue:3 Topics: Animals; Cattle; Nitroimidazoles; Rats; Ronidazole; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis, African; Trypanosomiasis, Bovine	1980
'Berenil' and nitroimidazole combinations in the treatment of Trypanosoma brucei infection with central nervous system involvement. International journal for parasitology, 1980, Volume: 10, Issue:1 Topics: Amidines; Animals; Benzamidines; Central Nervous System Diseases; Diminazene; Ethidium; Female; Isoxazoles; Mice; Nitroimidazoles; Phenanthridines; Ronidazole; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1980
Topical chemotherapy for experimental murine African CNS-trypanosomiasis: the successful use of the arsenical, melarsoprol, combined with the 5-nitroimidazoles, fexinidazole or MK-436. Tropical medicine & international health : TM & IH, 1996, Volume: 1, Issue:5 Topics: Administration, Topical; Animals; Antiprotozoal Agents; Dose-Response Relationship, Drug; Drug Combinations; Female; Gels; Melarsoprol; Mice; Nitroimidazoles; Trypanocidal Agents; Trypanosomiasis, African	1996
[Current status of trypanosomiasis]. Medecine tropicale : revue du Corps de sante colonial, 1997, Volume: 57, Issue:3 Suppl Topics: Africa; Animals; Autoantibodies; Blood-Brain Barrier; Brain Diseases; Follow-Up Studies; Forecasting; Humans; Incidence; Melarsoprol; Nitroimidazoles; Pentamidine; Population Surveillance; Protozoan Vaccines; Recurrence; Social Problems; Socioeconomic Factors; Survival Rate; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African	1997
Uptake of the nitroimidazole drug megazol by African trypanosomes. Biochemical pharmacology, 2000, Mar-15, Volume: 59, Issue:6 Topics: Africa; Animals; Biological Transport; Drug Interactions; Drug Resistance; Nitroimidazoles; Nucleosides; Receptors, Purinergic P2; Temperature; Thiadiazoles; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2000
Treatment of human African trypanosomiasis. Bulletin of the World Health Organization, 2000, Volume: 78, Issue:12 Topics: Acetanilides; Africa; Humans; Melarsoprol; Nitroimidazoles; Pentamidine; Suramin; Thiadiazoles; Trypanocidal Agents; Trypanosomiasis, African	2000
Antiparasitic nitroimidazoles. 8. Derivatives of 2-(4-formylstyryl)-5-nitro-1-vinylimidazole. Journal of medicinal chemistry, 1975, Volume: 18, Issue:2 Topics: Acetals; Animals; Chagas Disease; Dose-Response Relationship, Drug; Hydrazones; Mice; Nitroimidazoles; Structure-Activity Relationship; Styrenes; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma cruzi; Trypanosomiasis, African	1975
Antiparasitic nitroimidazoles. 9. Synthesis of some 2-(4-dialkylaminomethylstyryl)-and 2-(4-amidinostyryl)5-nitro-1-vinylimidazoles. Journal of medicinal chemistry, 1975, Volume: 18, Issue:4 Topics: Amidines; Animals; Chagas Disease; Mice; Nitroimidazoles; Styrenes; Trypanocidal Agents; Trypanosomiasis, African; Vinyl Compounds	1975
Subcurative chemotherapy and fatal post-treatment reactive encephalopathies in African trypanosomiasis. Lancet (London, England), 1992, Apr-18, Volume: 339, Issue:8799 Topics: Adolescent; Adult; Animals; Arsenicals; Brain; Brain Diseases; Child; Child, Preschool; Diminazene; Female; Humans; Male; Mice; Nitroimidazoles; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1992
Chemotherapy of CNS-trypanosomiasis: combination chemotherapy with a 5-nitroimidazole (MK 436), an arsenical (Cymelarsan) and suramin. Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1991, Volume: 42, Issue:3 Topics: Animals; Arsenicals; Brain Diseases; Disease Models, Animal; Drug Therapy, Combination; Female; Mice; Nitroimidazoles; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1991
Chemotherapy of CNS-trypanosomiasis: the combined use of the arsenicals and nitro-compounds. Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1991, Volume: 42, Issue:2 Topics: Animals; Antiprotozoal Agents; Arsenicals; Brain Diseases; Drug Synergism; Drug Therapy, Combination; Female; Ketoconazole; Metronidazole; Mice; Nifurtimox; Nitro Compounds; Nitroimidazoles; Oxidation-Reduction; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1991
[Action of drugs tested in an acellular medium and in mice infected with Trypanosoma brucei brucei]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1988, Volume: 81, Issue:3 Pt 2 Topics: Acetanilides; Animals; Culture Media; Cyclosporins; Eflornithine; In Vitro Techniques; Melarsoprol; Mice; Mitoguazone; Nitroimidazoles; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1988
[Efficacy of Ro 15-0216 against human strains of Trypanosoma gambiense maintained in rodents. A preliminary study]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1988, Volume: 81, Issue:3 Pt 2 Topics: Acetanilides; Administration, Oral; Animals; Humans; Injections, Intraperitoneal; Mice; Nitroimidazoles; Rats; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African	1988
[Treatment of experimental trypanosomiasis of sheep caused by Trypanosoma brucei brucei: efficacy of Ro 15-0216 (a 2-nitroimidazole derivative)]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1988, Volume: 81, Issue:3 Pt 2 Topics: Acetanilides; Animals; Nitroimidazoles; Sheep; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1988
Trypanocidal activity of a 5-substituted 2-nitroimidazole compound (Ro 15-0216) in mice. Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1987, Volume: 38, Issue:3 Topics: Acetanilides; Animals; Drug Therapy, Combination; Female; Male; Mice; Nitroimidazoles; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African	1987
The treatment of Trypanosoma (Nannomonas) simiae in pigs with diminazene aceturate in combination with a 5-substituted 2-nitroimidazole compound (Ro 15-0216). Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1987, Volume: 38, Issue:3 Topics: Acetanilides; Amidines; Animals; Diminazene; Drug Therapy, Combination; Female; Male; Mice; Nitroimidazoles; Swine; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African	1987