Page last updated: 2024-08-21

azomycin and Innate Inflammatory Response

azomycin has been researched along with Innate Inflammatory Response in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.00)18.2507
2000's6 (24.00)29.6817
2010's16 (64.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Arana-Argaez, VE; Bottazzi, ME; Cruz-Chan, JV; Dumonteil, E; Dzul-Huchim, VM; Gusovsky, F; Hotez, P; Martinez-Vega, PP; Ortega-Lopez, J; Ramirez-Sierra, MJ; Rosado-Vallado, ME; Villanueva-Lizama, LE1
Campos-Estrada, C; Denegri, M; González-Herrera, F; Kemmerling, U; Maya, JD; Urarte, E; Villalón, L1
Caldas, IS; Chagas-Paula, DA; Diniz, LF; Fernandes, VHC; Gonçalves-Santos, E; Mazzeti, AL; Novaes, RD; Oliveira, CM; Rodrigues, MR; Veloso, MP; Vilas-Boas, DF1
Cevey, ÁC; Donato, M; Gelpi, RJ; Goren, NB; Mirkin, GA; Penas, FN; Rada, MJ1
Arrúa, EC; Esteva, MI; Fichera, LE; Rial, MS; Salomon, CJ; Scalise, ML1
Camargo, RS; Carneiro, ZA; de Albuquerque, S; do Vale, GT; Portapilla, GB; Providello, MV; Tirapelli, CR1
Chin, CM; da Rosa, JA; de Andrade, CR; Dos Santos, JL; Scarim, CB1
Gonçalves, RV; Maldonado, IRSC; Mendonça, AAS; Natali, AJ; Novaes, RD; Souza-Silva, TG; Talvani, A1
Aminuddin, A; Fujisaka, S; Goda, N; Ikutani, M; Mahmood, A; Nagai, Y; Takatsu, K; Takikawa, A; Tobe, K; Tsuneyama, K; Usui, I1
Carneiro, ZA; da Silva, RS; Milanezi, C; Santos, M; Sesti-Costa, R; Silva, GK; Silva, JS; Silva, MC1
Araújo, MS; Carneiro, CM; Lana, Md; Machado-de-Assis, GF; Martins, HR; Martins-Filho, OA; Oliveira, MT; Oliveira-Silva, JC; Paiva, NC1
Araujo, AP; Giorgio, S1
Bastos, DS; Cardoso, SA; Gonçalves, WG; Novaes, RD; Oliveira, JM; Oliveira, LL; Penitente, AR; Santos, EC; Talvani, A1
Choi, IW; Choi, JS; Choi, YH; Jang, WH; Jung, WK; Kim, GY; Lee, DS; Lee, YM; Paeng, SH; Park, S; Park, WS; Seo, SK1
de Paula Costa, G; Horta, AL; Leite, AL; Natali, AJ; Neves, CA; Penitente, AR; Shrestha, D; Talvani, A1
Cevey, ÁC; Goren, NB; Mirkin, GA; Penas, FN1
Carnovale, CE; Catania, VA; de Luján Alvarez, M; Francés, DE; Lambertucci, F; Martín-Sanz, P; Motiño, O; Quiroga, AD; Rigalli, JP; Ronco, MT; Villar, S1
Gilbert, RE; Kelly, DJ; Langham, RG; Tiauw, V; Wiggins, KJ; Zhang, Y1
Bottasso, E; Bottasso, O; Manarin, R; Revelli, S; Serra, E1
Cruz-Zetina, G; del Rio-Rodriguez, R; López, R; Monteon, V; Ramos-Ligonio, A1
Bozza, MT; Freire-De-Lima, CG; Gibaldi, D; Heise, N; Mendonça-Previato, L; Previato, JO; Saraiva, VB1
Alves, CF; Bahia, MT; Carneiro, CM; Cruz, RE; Lana, M; Machado-Coelho, GL; Martins, HR; Tafuri, WL; Toledo, MJ; Veloso, VM1
Amigorena, S; Bottasso, O; Guermonprez, P; Nocito, AL; Pascutti, MF; Pitashny, M; Revelli, S; Serra, E; Wietzerbin, J1
Albina, JE; Henry, WL; Louis, CA; Mastrofrancesco, B; Reichner, JS; Vessella, JA1
Bäckström, AC; Happonen, RP; Ylipaavalniemi, P1

Trials

2 trial(s) available for azomycin and Innate Inflammatory Response

ArticleYear
Effect of statins on inflammation and cardiac function in patients with chronic Chagas disease: A protocol for pathophysiological studies in a multicenter, placebo-controlled, proof-of-concept phase II trial.
    PloS one, 2023, Volume: 18, Issue:1

    Topics: Atorvastatin; Chagas Disease; Clinical Trials, Phase II as Topic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Multicenter Studies as Topic; Nitroimidazoles; Persistent Infection; Randomized Controlled Trials as Topic; Trypanocidal Agents; Trypanosoma cruzi

2023
Prophylactic use of phenoxymethylpenicillin and tinidazole in mandibular third molar surgery, a comparative placebo controlled clinical trial.
    The British journal of oral & maxillofacial surgery, 1990, Volume: 28, Issue:1

    Topics: Adult; Analysis of Variance; Chi-Square Distribution; Double-Blind Method; Female; Humans; Inflammation; Male; Mandible; Molar, Third; Nitroimidazoles; Pain Measurement; Pain, Postoperative; Penicillin V; Randomized Controlled Trials as Topic; Tinidazole; Tooth Extraction

1990

Other Studies

23 other study(ies) available for azomycin and Innate Inflammatory Response

ArticleYear
Vaccine-linked chemotherapy with a low dose of benznidazole plus a bivalent recombinant protein vaccine prevents the development of cardiac fibrosis caused by Trypanosoma cruzi in chronically-infected BALB/c mice.
    PLoS neglected tropical diseases, 2022, Volume: 16, Issue:9

    Topics: Adjuvants, Immunologic; Animals; Chagas Disease; Dogs; Fibrosis; Humans; Inflammation; Mice; Mice, Inbred BALB C; Nitroimidazoles; Perforin; Protozoan Vaccines; Recombinant Proteins; Toll-Like Receptor 4; Trypanosoma cruzi; Vaccines, Combined; Vaccines, DNA

2022
Sesquiterpene lactone potentiates the immunomodulatory, antiparasitic and cardioprotective effects on anti-Trypanosoma cruzi specific chemotherapy.
    International immunopharmacology, 2019, Volume: 77

    Topics: Animals; Antiparasitic Agents; Cardiotonic Agents; Cell Line; Chagas Disease; Cytokines; Female; Immunologic Factors; Inflammation; Lactones; Mice; Myocarditis; Nitroimidazoles; Parasitemia; Rats; Sesquiterpenes; Trypanosoma cruzi; Tumor Necrosis Factor-alpha

2019
Treatment with Fenofibrate plus a low dose of Benznidazole attenuates cardiac dysfunction in experimental Chagas disease.
    International journal for parasitology. Drugs and drug resistance, 2017, Volume: 7, Issue:3

    Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Diastole; Fenofibrate; Fibrosis; Humans; Inflammation; Interleukin-6; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide Synthase Type II; Nitroimidazoles; PPAR alpha; Stroke Volume; Trypanocidal Agents; Trypanosoma cruzi; Tumor Necrosis Factor-alpha; Ventricular Dysfunction; Ventricular Function

2017
Elucidating the impact of low doses of nano-formulated benznidazole in acute experimental Chagas disease.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:12

    Topics: Animals; Antibodies, Protozoan; Cell Line; Chagas Disease; Chlorocebus aethiops; Disease Models, Animal; DNA, Protozoan; Drug Carriers; Female; Heart; Inflammation; Mice; Mice, Inbred C3H; Nanoparticles; Nitroimidazoles; Reactive Oxygen Species; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells

2017
Benefits of Ascorbic Acid in Association with Low-Dose Benznidazole in Treatment of Chagas Disease.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:9

    Topics: Animals; Antioxidants; Ascorbic Acid; Chagas Disease; Drug Therapy, Combination; Inflammation; Lipid Peroxidation; Male; Mice; Nitroimidazoles; Oxidation-Reduction; Reactive Oxygen Species; Trypanocidal Agents; Trypanosoma cruzi

2018
Hydroxymethylnitrofurazone treatment in indeterminate form of chronic Chagas disease: Reduced intensity of tissue parasitism and inflammation-A histopathological study.
    International journal of experimental pathology, 2018, Volume: 99, Issue:5

    Topics: Animals; Chagas Disease; Disease Models, Animal; Inflammation; Kidney; Liver; Male; Mice; Muscle, Skeletal; Nitrofurazone; Nitroimidazoles; Trypanosoma cruzi

2018
Concomitant exercise training attenuates the cardioprotective effects of pharmacological therapy in a murine model of acute infectious myocarditis.
    Life sciences, 2019, Aug-01, Volume: 230

    Topics: Animals; Antioxidants; Cardiotonic Agents; Catalase; Chagas Cardiomyopathy; Chagas Disease; Cytokines; Disease Models, Animal; Heart; Inflammation; Interleukin-10; Male; Myocarditis; Myocardium; Nitric Oxide; Nitroimidazoles; Parasitemia; Physical Conditioning, Animal; Rats; Rats, Wistar; Superoxide Dismutase; Trypanosoma cruzi; Tumor Necrosis Factor-alpha

2019
Adipose tissue hypoxia induces inflammatory M1 polarity of macrophages in an HIF-1α-dependent and HIF-1α-independent manner in obese mice.
    Diabetologia, 2013, Volume: 56, Issue:6

    Topics: Adipose Tissue; Alleles; Animals; Bone Marrow Cells; Cell Polarity; Flow Cytometry; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Nitroimidazoles; Phenotype

2013
Ruthenium complex with benznidazole and nitric oxide as a new candidate for the treatment of chagas disease.
    PLoS neglected tropical diseases, 2014, Volume: 8, Issue:10

    Topics: Animals; Chagas Disease; Drug Resistance; Drug Therapy, Combination; Female; Heart; Humans; Inflammation; Mice; Nitric Oxide; Nitroimidazoles; Parasitemia; Ruthenium; Trypanocidal Agents; Trypanosoma cruzi

2014
Experimental benznidazole treatment of Trypanosoma cruzi II strains isolated from children of the Jequitinhonha Valley, Minas Gerais, Brazil, with Chagas disease.
    Memorias do Instituto Oswaldo Cruz, 2015, Volume: 110, Issue:1

    Topics: Animals; Antibodies, Protozoan; Area Under Curve; Brazil; Chagas Disease; Child; Disease Models, Animal; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Female; Fibrosis; Flow Cytometry; Humans; Inflammation; Mice; Myocardium; Nitroimidazoles; Parasitemia; Polymerase Chain Reaction; Primary Cell Culture; Remission Induction; Statistics, Nonparametric; Trypanocidal Agents; Trypanosoma cruzi

2015
Immunohistochemical evidence of stress and inflammatory markers in mouse models of cutaneous leishmaniosis.
    Archives of dermatological research, 2015, Volume: 307, Issue:8

    Topics: Animals; Biomarkers; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Immunohistochemistry; Inflammation; Leishmania; Leishmaniasis, Cutaneous; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitric Oxide; Nitroimidazoles; p38 Mitogen-Activated Protein Kinases; Vascular Endothelial Growth Factor A

2015
Modulation of oxidative and inflammatory cardiac response by nonselective 1- and 2-cyclooxygenase inhibitor and benznidazole in mice.
    The Journal of pharmacy and pharmacology, 2015, Volume: 67, Issue:11

    Topics: Administration, Oral; Animals; Antioxidants; Catalase; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glutathione Peroxidase; Ibuprofen; Immunosuppressive Agents; Inflammation; Male; Mice; Nitroimidazoles; Oxidative Stress; Random Allocation; Reactive Nitrogen Species; Reactive Oxygen Species; Superoxide Dismutase

2015
YCG063 inhibits Pseudomonas aeruginosa LPS-induced inflammation in human retinal pigment epithelial cells through the TLR2-mediated AKT/NF-κB pathway and ROS-independent pathways.
    International journal of molecular medicine, 2015, Volume: 36, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Cell Line; Cell Survival; Humans; Hydrazones; Inflammation; Lipopolysaccharides; NF-kappa B; Nitroimidazoles; Proto-Oncogene Proteins c-akt; Pseudomonas aeruginosa; Reactive Oxygen Species; Retinal Pigment Epithelium; Signal Transduction; Toll-Like Receptor 2

2015
Enalapril in Combination with Benznidazole Reduces Cardiac Inflammation and Creatine Kinases in Mice Chronically Infected with Trypanosoma cruzi.
    The American journal of tropical medicine and hygiene, 2015, Volume: 93, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Chagas Cardiomyopathy; Enalapril; Inflammation; Male; Mice; Mice, Inbred C57BL; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2015
Low-dose benznidazole treatment results in parasite clearance and attenuates heart inflammatory reaction in an experimental model of infection with a highly virulent Trypanosoma cruzi strain.
    International journal for parasitology. Drugs and drug resistance, 2016, Volume: 6, Issue:1

    Topics: Animals; Cells, Cultured; Chagas Cardiomyopathy; Chagas Disease; Creatine Kinase; Disease Models, Animal; Dose-Response Relationship, Drug; Heart; Humans; Immunologic Factors; Inflammation; Interleukin-6; Mice; Mice, Inbred BALB C; Myocytes, Cardiac; NF-kappa B; Nitric Oxide Synthase Type II; Nitroimidazoles; Parasite Load; Parasitemia; Trypanocidal Agents; Trypanosoma cruzi; Tumor Necrosis Factor-alpha

2016
Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis.
    Toxicology and applied pharmacology, 2017, Jan-15, Volume: 315

    Topics: Animals; Antioxidants; Chagas Disease; Disease Models, Animal; Down-Regulation; Inflammation; Liver; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Nitroimidazoles; Oxidative Stress; Sepsis; Toll-Like Receptor 4; Trypanocidal Agents

2017
Perindopril attenuates tubular hypoxia and inflammation in an experimental model of diabetic nephropathy in transgenic Ren-2 rats.
    Nephrology (Carlton, Vic.), 2008, Volume: 13, Issue:8

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Fibrosis; Hypoxia; Immunohistochemistry; Inflammation; Kidney Tubules; Macrophages; Nitroimidazoles; Osteopontin; Perindopril; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System; Time Factors

2008
Beneficial effects of benznidazole during an infectious-based situation of systemic inflammatory response: cecal ligation and puncture.
    The American journal of tropical medicine and hygiene, 2008, Volume: 79, Issue:5

    Topics: Animals; Bacteremia; Chagas Disease; Enzyme-Linked Immunosorbent Assay; Inflammation; Male; Mice; Mice, Inbred C57BL; Nitroimidazoles; Trypanocidal Agents; Tumor Necrosis Factor-alpha

2008
Decreased intensity of inflammation in benznidazole-treated mice inoculated with Trypanosoma cruzi I stocks from Mexico and persistence of circulating parasites.
    The American journal of tropical medicine and hygiene, 2012, Volume: 87, Issue:4

    Topics: Animals; Cardiomyopathies; Chagas Disease; Genotype; Heart; Inflammation; Mexico; Mice; Mice, Inbred BALB C; Muscle, Skeletal; Nitroimidazoles; Parasitemia; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma cruzi

2012
Proinflammatory and cytotoxic effects of hexadecylphosphocholine (miltefosine) against drug-resistant strains of Trypanosoma cruzi.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:11

    Topics: Animals; Antiprotozoal Agents; Chagas Disease; Drug Resistance; Exudates and Transudates; Inflammation; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Nitroimidazoles; omega-N-Methylarginine; Phosphorylcholine; Survival Analysis; Trypanosoma cruzi; Tumor Necrosis Factor-alpha

2002
Effects of specific treatment on parasitological and histopathological parameters in mice infected with different Trypanosoma cruzi clonal genotypes.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:6

    Topics: Animals; Antiprotozoal Agents; Chagas Disease; Cloning, Molecular; Female; Genotype; Heart; Inflammation; Itraconazole; Mice; Mice, Inbred BALB C; Myocardium; Nitroimidazoles; Trypanosoma cruzi; Urogenital System

2004
Benznidazole, a drug used in Chagas' disease, ameliorates LPS-induced inflammatory response in mice.
    Life sciences, 2004, Dec-24, Volume: 76, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chagas Disease; DNA Primers; Dose-Response Relationship, Drug; Endotoxemia; Flow Cytometry; Inflammation; Interleukin-10; Interleukin-12; Interleukin-6; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroimidazoles; Peritoneal Lavage; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Trypanocidal Agents; Tumor Necrosis Factor-alpha

2004
HIF-1 expression in healing wounds: HIF-1alpha induction in primary inflammatory cells by TNF-alpha.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:6

    Topics: Animals; Cell Line; Endothelial Growth Factors; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interleukin-1; Lymphokines; Male; Nitroimidazoles; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Time Factors; Transcription Factors; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wound Healing

2001