Page last updated: 2024-08-21

azomycin and Head and Neck Neoplasms

azomycin has been researched along with Head and Neck Neoplasms in 95 studies

Research

Studies (95)

Timeframe	Studies, this research(%)	All Research%
pre-1990	20 (21.05)	18.7374
1990's	7 (7.37)	18.2507
2000's	31 (32.63)	29.6817
2010's	33 (34.74)	24.3611
2020's	4 (4.21)	2.80

Authors

Authors	Studies
Diaz-Dussan, D; El-Saidi, H; Ismail, IH; Kumar, P; Macdonald, D; Mashayekhi, F; Narain, R; Nation, PN; Rashed, FB; Ricardo, C; Sokhi, S; Stoica, AC; Weinfeld, M; Wiebe, LI; Yang, XH	1
de Bree, R; H A M Kaanders, J; Philippens, MEP; Smits, HJG; Swartz, JE; Willems, SM	1
Harada, R; Imaizumi, A; Inubushi, M; Kershaw, J; Koizumi, M; Obata, T; Saga, T; Tachibana, Y; Tanimoto, K; Uno, T; Yoshikawa, K; Zhang, MR	1
Fu, Z; Ho, F; Hu, M; Lee, NY; Li, M; Lian, M; Ma, L; Xie, P; Yang, G; Yu, J; Zhao, S; Zheng, J	1
Hansen, CR; Johansen, J; Kallehauge, J; Mortensen, LS; Overgaard, J; Primdahl, H; Saksø, M	1
Baker, LCJ; Bhide, SA; Box, C; d'Arcy, JA; Dunlop, A; Eccles, SA; Harrington, KJ; Hopkinson, G; Koh, DM; Leach, MO; Mcquaid, D; Newbold, KL; Nutting, CM; Panek, R; Richardson, C; Riddell, AM; Robinson, SP; Schmidt, MA; Welsh, L; Wong, KH	1
Bender, S; Grgic, I; Guckenberger, M; Nytko, KJ; Ott, J; Pruschy, M; Riesterer, O	1
Kuge, Y; Matsumoto, H; Nishijima, KI; Ogawa, M; Shiga, T; Shimizu, Y; Tamaki, N; Yasui, H; Zhao, S	1
Dadgar, S; Rajaram, N; Troncoso, JR	1
Bohlander, SK; Budhani, P; Butt, S; Caporiccio, L; Chaplin, JM; Chiorean, EG; Curran, MA; Grénman, RA; Hart, CP; Hicks, KO; Hong, CR; Hunter, FW; Jalal, SI; Jamieson, SM; Kakadia, PM; Kee, D; Knowlton, NS; Kondratyev, MK; Lee, TW; Li, D; Liu, A; Lynch, CR; Macann, AM; McIvor, NP; McKee, TD; Nemunaitis, JJ; Poonawala-Lohani, N; Print, CG; Senzer, NN; Shome, A; Tsai, P; Wilson, WR; Wong, WW; Wouters, BG; Zaidi, M	1
Baumann, M; Bütof, R; Gudziol, V; Hering, S; Krause, M; Löck, S; Meneceur, S; Rehm, M; von Neubeck, C	1
Chaplin, JM; Harms, JK; Hunter, FW; Jamieson, SMF; Kee, D; Lai, A; Lee, TW; Macann, AMJ; McIvor, NP; Wang, T; Wilson, WR	1
Busk, M; Horsman, MR; Iversen, AB; Jakobsen, S; Ji, X; Lee, DY; Mortensen, LS; Nordsmark, M; Overgaard, J; Raleigh, JR	1
Bruine de Bruin, L; Halmos, GB; Langendijk, JA; Pruim, J; Steenbakkers, RJ; van der Laan, BF	1
Bol, A; Differding, S; Grégoire, V; Hanin, FX; Labar, D; Lee, JA; Servagi-Vernat, S	1
Giraud, P; Servagi-Vernat, S	1
Bollineni, VR; Brouwer, CL; Groen, HJ; Halmos, GB; Koole, MJ; Langendijk, JA; Oosting, SF; Pruim, J; Steenbakkers, RJ; Vlasman, R; Widder, J; Wiegman, EM	1
Bol, A; Differding, S; Grégoire, V; Hanin, FX; Labar, D; Lee, JA; Servagi-Vernat, S; Sterpin, E	1
Galoforo, S; Grills, IS; Kane, JL; Krueger, SA; Marples, B; Wilson, GD; Wobb, J	1
Brunetti, JC; Chien, D; Kolb, H; Lambin, P; Moon, DH; Srinivas, SM; Subramaniam, RM; Szardenings, K; van Elmpt, W; Waxman, A; Zegers, CM	1
Bollineni, VR; Bruine de Bruin, L; de Bock, GH; Halmos, GB; Langendijk, JA; Pruim, J; Schuuring, E; Slagter-Menkema, L; Steenbakkers, RJ; van der Laan, BF; van der Wal, JE; van Hemel, BM; Wachters, JE	1
Brown, KR; Goldstein, DP; Gu, Y; Hunter, FW; Joshi, N; Ketela, T; Koritzinsky, M; Moffat, J; Rischin, D; Shalev, Z; Solomon, B; Sreebhavan, S; Vellanki, RN; Wang, J; Weinreb, I; Wilson, WR; Wouters, BG; Young, RJ	1
Binns, D; Bressel, M; Graves, EE; Hicks, RJ; Le, QT; Peters, L; Rischin, D; Young, RJ	1
Fujibayashi, Y; Harada, R; Inubushi, M; Koizumi, M; Obata, T; Saga, T; Tanimoto, K; Uno, T; Yoshikawa, K; Zhang, MR	1
Baumann, M; Mönnich, D; Thorwarth, D; Wack, LJ; Yaromina, A; Zips, D	1
Castellano, I; Charles-Edwards, E; Clarke, P; Fisher, C; Harrington, K; Leach, M; Mears, D; Newbold, K; Nutting, C; Rhys-Evans, P; Sohaib, A	1
Abrams, DN; Kumar, P; McEwan, AJ; Postema, EJ; Riauka, TA; Richmond, DA; Wiebe, LI	1
Boerman, OC; Bussink, J; Franssen, GM; Hoeben, BA; Kaanders, JH; Oosterwijk, E; Oyen, WJ; Rijken, PF; Troost, EG; van Dongen, GA	1
Astner, ST; Nüsslin, F; Shi, K; Souvatzoglou, M; Vaupel, P; Wilkens, JJ; Ziegler, SI	1
Betts, G; Bonington, SC; Buckley, DL; Donaldson, SB; Homer, JJ; Kershaw, LE; Slevin, NJ; Valentine, H; West, CM	1
Bussink, J; Kaanders, JH; Lok, J; Rademakers, SE; van der Kogel, AJ	1
Busk, M; Horsman, MR; Jakobsen, S; Mueller-Klieser, W; Overgaard, J; Steiniche, T; Walenta, S	1
Bezak, E; Filip, SM; Marcu, LG	1
Bussink, J; Hoogsteen, IJ; Kaanders, JH; Lok, J; Marres, HA; Rijken, PF; van den Hoogen, FJ	1
Bartlett, R; Carlin, S; Humm, JL; McCall, KC; Reese, M	1
Chen, L; Guan, Y; Kolb, HC; Walsh, JC; Zhang, J; Zhang, Z	1
Bussink, J; Grénman, R; Iida, M; Kaanders, JH; Span, PN; Stegeman, H; van der Kogel, AJ; Verheijen, MM; Waaijer, SJ; Wheeler, DL	1
Alsner, J; Busk, M; Jakobsen, S; Johansen, J; Kallehauge, J; Lassen, P; Mortensen, LS; Nordsmark, M; Overgaard, J; Petersen, H; Petersen, J; Primdahl, H; Sørensen, BS; Theil, J; Toustrup, K	1
Dierckx, RA; Halmos, GB; Langedijk, JA; Pruim, J; Roodenburg, JL; van der Laan, BF; Wedman, J	1
Balm, AJ; Begg, AC; Haustermans, KM; Hoebers, FJ; Hoefnagel, CA; Janssen, HL; Nunn, AD; Olmos, AV; Sprong, D	1
Balm, AJ; Begg, AC; Blijweert, E; Blommestijn, G; Delaere, P; Haustermans, KM; Hoebers, FJ; Hofland, I; Janssen, HL; Raleigh, JA; Sciot, R; Semenza, GL; Sprong, D; van Velthuysen, ML; Varia, MA	1
Bussink, J; de Wilde, PC; Kaanders, JH; Ljungkvist, AS; Marres, HA; Pop, LA; Raleigh, JA; van den Hoogen, FJ; van der Kogel, AJ; Wijffels, KI	1
Eskola, O; Grönroos, T; Lehtiö, K; Minn, H; Nyman, S; Oikonen, V; Roivainen, A	1
Bussink, J; Kaanders, JH; van der Kogel, AJ	2
Balm, AJ; Begg, AC; Goethals, L; Haustermans, KM; Hoebers, FJ; Janssen, HL; Sprong, D; Stratford, IJ; Williams, KJ	1
Eskola, O; Grénman, R; Grönroos, T; Lehtiö, K; Minn, H; Oikonen, V; Sillanmäki, L; Viljanen, T	1
Harrison, LB; Hu, K	1
Amin, K; Arcasoy, MO; Chou, SC; Haroon, ZA; Raleigh, JA; Varia, M	1
Boerman, OC; Bussink, J; Kaanders, JH; Peters, JP; Rijken, PF; Troost, EG; van der Kogel, AJ; van Eerd, J	1
Hoogsteen, IJ; Kaanders, JH; Marres, HA; Peeters, WJ; Rijken, PF; van den Hoogen, FJ; van der Kogel, AJ	1
Homer, JJ; Isa, AY; Slevin, NJ; Ward, TH; West, CM	1
Boerman, OC; Bussink, J; Kaanders, JH; Laverman, P; Lok, J; Oyen, WJ; Philippens, M; Troost, EG; van der Kogel, AJ	1
Balm, A; Barbé, B; Begg, AC; De Schutter, H; Gregoire, V; Haustermans, K; Mahy, P; Nuyts, S; Spaepen, M; Vander Poorten, V	1
Alber, M; Eschmann, SM; Holzner, F; Paulsen, F; Thorwarth, D	1
Beck, R; Grosu, AL; Krause, BJ; Machulla, HJ; Picchio, M; Piert, M; Reischl, G; Röper, B; Souvatzoglou, M; Wester, HJ	1
Mankoff, DA; Rajendran, JG	1
Kaanders, JH; Marres, HA; Peters, JP; Rijken, PF; van der Kogel, AJ; Wijffels, KI	1
Le, QT	1
Dobritz, M; Grosu, AL; Jacob, V; Machulla, HJ; Molls, M; Piert, M; Reischl, G; Röper, B; Schwaiger, M; Souvatzoglou, M; Wester, HJ; Wiedenmann, N	1
Christian, N; De Bast, M; Geets, X; Gillart, J; Grégoire, V; Labar, D; Lee, J; Levêque, P; Lonneux, M; Mahy, P	1
Boerman, OC; Bussink, J; Kaanders, JH; Laverman, P; Lok, J; Oyen, WJ; Philippens, ME; Troost, EG; van der Kogel, AJ	1
Awwad, HK; Barsoum, M; El Badawy, S; El Baki, HA; El Merzabani, M; Ezzat, S; Omar, S; Zaki, A	1
Onoyama, Y	1
Dische, S	2
Cridland, S; Sealy, R	1
Demange, L; Froissart, D; Nguyen, TD; Panis, X	1
Kogelnik, HD	1
Phillips, TL; Stetz, J; Wasserman, TH	2
Arcangeli, G; Chaplain, G; Gonzalez, D; Horiot, JC; Svoboda, V; Van den Bogaert, W; van der Schueren, E	1
Dawes, PJ; Henk, JM; Moore, JL; Paterson, IC	1
Moore, JL; Newman, H; Paterson, IC; Venables, S	1
Fazekas, JT; Goodman, RL; McLean, CJ	1
Arcangeli, G; Barocas, A; Mauro, F; Nervi, C; Spanò, M; Tabocchini, A	1
Kogelnik, HD; Mamoli, B; Reinartz, G; Seitz, W; Stark, H; Szepesi, T; Wessely, P; Wurst, F	1
Chapman, JD; Golberg, LE; Groshar, D; Hoskinson, M; Mannan, RH; McEwan, AJ; Mercer, JR; Parliament, MB; Urtasun, RC; Wiebe, LI	1
Ballenger, CA; Calkins-Adams, DP; Fowler, WC; Novotny, DB; Raleigh, JA; Rinker, LH; Varia, MA; Weissler, MC	1
Ballenger, CA; Calkins-Adams, DP; Chou, SC; Novotny, DB; Raleigh, JA; Varia, MA	1
Bussink, J; de Wilde, PC; Kaanders, JH; Marres, HA; Raleigh, JA; Rijken, PF; van den Hoogen, FJ; van der Kogel, AJ; Wijffels, KI	1
Bono, EL; Chou, SC; Raleigh, JA; Thrall, DE; Varia, MA	1
Bergman, J; Eskola, O; Forsback, S; Grönroos, T; Haaparanta, M; Lehtiö, K; Marjamäki, P; Minn, H; Solin, O	1
Bergman, J; Eskola, O; Grénman, R; Grönroos, T; Kalliokoski, K; Lehtiö, K; Minn, H; Nuutila, P; Oikonen, V; Solin, O	1
Balm, A; Begg, AC; Blommestijn, G; Delaere, P; Hofland, I; Janssen, H; Raleigh, JA; Sciot, R; Sprong, D; Van Velthuyzen, L; Varia, M	1
Karim, AB	1
Sealy, R	1
Band, P; Chapman, JD; Fryer, CG; Rabin, HR; Urtasun, RC; Wilson, AF	1
Coleman, CN; Cosmatos, D; Davis, LW; Lee, DJ; Marcial, VA; Phillips, TL; Rubin, P; Wasserman, TH	1
Charreau, I; Chassagne, D; Eschwege, F; Malaise, EP; Sancho-Garnier, H	2
Coleman, N; Cosmatos, D; Davis, L; Lee, DJ; Marcial, V; Phillips, T; Stetz, J; Wasserman, TH	1
Wagner, W	1
Arcangeli, G; Chaplain, G; Gonzalez, D; Horiot, JC; Svoboda, V; Van den Bogaert, W; van der Schueren, E; Van Tongelen, C	1

Reviews

8 review(s) available for azomycin and Head and Neck Neoplasms

Article	Year
Head and neck tumor hypoxia imaging by 18F-fluoroazomycin-arabinoside (18F-FAZA)-PET: a review. Clinical nuclear medicine, 2014, Volume: 39, Issue:1 Topics: Animals; Cell Hypoxia; Cell Transformation, Neoplastic; Head and Neck Neoplasms; Humans; Nitroimidazoles; Positron-Emission Tomography	2014
[Metabolic tailoring in radiotherapy for head and neck cancer]. Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2014, Volume: 18, Issue:5-6 Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Clinical Trials as Topic; Diffusion Magnetic Resonance Imaging; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Misonidazole; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Image-Guided; Tumor Burden	2014
The role of PET imaging in overcoming radiobiological challenges in the treatment of advanced head and neck cancer. Cancer treatment reviews, 2012, Volume: 38, Issue:3 Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Cell Proliferation; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Nitroimidazoles; Positron-Emission Tomography; Radioisotopes; Radiotherapy, Image-Guided; Squamous Cell Carcinoma of Head and Neck	2012
Alternative PET tracers in head and neck cancer. A review. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2013, Volume: 270, Issue:10 Topics: Amino Acids; Antibodies, Monoclonal; Carbon Radioisotopes; Carcinoma, Squamous Cell; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Misonidazole; Nitroimidazoles; Nucleosides; Positron-Emission Tomography; Radiopharmaceuticals	2013
Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2003, Volume: 67, Issue:1 Topics: Antigens, Neoplasm; Biomarkers, Tumor; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; DNA-Binding Proteins; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Neoplasm Proteins; Nitroimidazoles; Nuclear Proteins; Oxygen; Radiation-Sensitizing Agents; Transcription Factors; Treatment Outcome; Vascular Endothelial Growth Factor A	2003
Impact of anemia in patients with head and neck cancer treated with radiation therapy. Current treatment options in oncology, 2005, Volume: 6, Issue:1 Topics: Anemia; Cell Hypoxia; Erythropoietin; Head and Neck Neoplasms; Humans; Neoplasm Recurrence, Local; Nitroimidazoles; Prognosis; Quality of Life; Risk Factors; Survival Analysis	2005
Hypoxia in head and neck cancer. The British journal of radiology, 2006, Volume: 79, Issue:946 Topics: Antibiotics, Antineoplastic; Basic Helix-Loop-Helix Transcription Factors; Biomarkers; Cell Hypoxia; Comet Assay; Head and Neck Neoplasms; Hemoglobins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Microelectrodes; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Prognosis; Radiation-Sensitizing Agents	2006
Radiosensitizers in the treatment of squamous cell carcinoma of the head and neck. Clinical otolaryngology and allied sciences, 1977, Volume: 2, Issue:4 Topics: Animals; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Hypoxia; Metronidazole; Mice; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents	1977

Trials

24 trial(s) available for azomycin and Head and Neck Neoplasms

Article	Year
Correlation and colocalization of HIF-1α and pimonidazole staining for hypoxia in laryngeal squamous cell carcinomas: A digital, single-cell-based analysis. Oral oncology, 2022, Volume: 128 Topics: Biomarkers; Biomarkers, Tumor; Cell Hypoxia; Head and Neck Neoplasms; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Laryngeal Neoplasms; Nitroimidazoles; Prognosis; Squamous Cell Carcinoma of Head and Neck; Staining and Labeling	2022
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma. JCI insight, 2018, 08-23, Volume: 3, Issue:16 Topics: Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Cell Line, Tumor; Chemoradiotherapy; Drug Resistance, Neoplasm; Exome Sequencing; Female; Gene Knockdown Techniques; Head and Neck Neoplasms; Humans; Inhibitory Concentration 50; Middle Aged; Nitroimidazoles; Papillomaviridae; Phosphoramide Mustards; Prodrugs; Progression-Free Survival; Response Evaluation Criteria in Solid Tumors; Squamous Cell Carcinoma of Head and Neck; Xenograft Model Antitumor Assays; Young Adult	2018
Hypoxia-guided adaptive radiation dose escalation in head and neck carcinoma: a planning study. Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:7 Topics: Aged; Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Female; Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy Planning, Computer-Assisted; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed	2015
Repeatability of hypoxia PET imaging using [¹⁸F]HX4 in lung and head and neck cancer patients: a prospective multicenter trial. European journal of nuclear medicine and molecular imaging, 2015, Volume: 42, Issue:12 Topics: Aged; Biological Transport; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Nitroimidazoles; Positron-Emission Tomography; Prospective Studies; Reproducibility of Results; Triazoles	2015
Prognostic value of PET/CT with (18)F-fluoroazomycin arabinoside for patients with head and neck squamous cell carcinomas receiving chemoradiotherapy. Annals of nuclear medicine, 2016, Volume: 30, Issue:3 Topics: Carcinoma, Squamous Cell; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Prognosis; Squamous Cell Carcinoma of Head and Neck	2016
Initial results of hypoxia imaging using 1-alpha-D: -(5-deoxy-5-[18F]-fluoroarabinofuranosyl)-2-nitroimidazole ( 18F-FAZA). European journal of nuclear medicine and molecular imaging, 2009, Volume: 36, Issue:10 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Female; Fluorine Radioisotopes; Glioma; Head and Neck Neoplasms; Humans; Hypoxia; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Young Adult	2009
FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: results from the DAHANCA 24 trial. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 105, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Lymph Nodes; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Prognosis; Tomography, X-Ray Computed	2012
Phase 1 study to identify tumour hypoxia in patients with head and neck cancer using technetium-99m BRU 59-21. European journal of nuclear medicine and molecular imaging, 2002, Volume: 29, Issue:9 Topics: Cell Hypoxia; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Injections, Intravenous; Laryngeal Neoplasms; Magnetic Resonance Imaging; Neoplasm Staging; Nitroimidazoles; Normal Distribution; Organotechnetium Compounds; Radiation-Sensitizing Agents; Radiopharmaceuticals; Tomography, Emission-Computed	2002
Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer. Cancer research, 2002, Dec-01, Volume: 62, Issue:23 Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Carbon Dioxide; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Proteins; Niacinamide; Nitroimidazoles; Oxygen; Predictive Value of Tests; Treatment Outcome	2002
Quantifying tumour hypoxia with fluorine-18 fluoroerythronitroimidazole ([18F]FETNIM) and PET using the tumour to plasma ratio. European journal of nuclear medicine and molecular imaging, 2003, Volume: 30, Issue:1 Topics: Blood Flow Velocity; Carcinoma, Squamous Cell; Cell Hypoxia; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Muscle, Skeletal; Nitroimidazoles; Oxygen Radioisotopes; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed	2003
Determination of tumour hypoxia with [18F]EF3 in patients with head and neck tumours: a phase I study to assess the tracer pharmacokinetics, biodistribution and metabolism. European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:7 Topics: Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypoxia; Laryngeal Neoplasms; Male; Middle Aged; Nitroimidazoles; Pharyngeal Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution	2008
A study of the effect of misonidazole in conjunction with radiotherapy for the treatment of head and neck cancer. MRC working party on misonidazole in head and neck cancer. The British journal of radiology, 1984, Volume: 57, Issue:679 Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Radiotherapy; Radiotherapy Dosage; Random Allocation	1984
[Clinical trials of hypoxic cell sensitizer misonidazole]. Gan no rinsho. Japan journal of cancer clinics, 1983, Volume: 29, Issue:6 Topics: Brain Neoplasms; Clinical Trials as Topic; Drug Evaluation; Female; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Random Allocation; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms	1983
Clinical trials with hypoxic cell sensitizers-the European experience. Progress in clinical and biological research, 1983, Volume: 132D Topics: Animals; Brain Neoplasms; Clinical Trials as Topic; Head and Neck Neoplasms; Humans; Methods; Misonidazole; Neoplasms; Nitroimidazoles; Urinary Bladder Neoplasms	1983
The treatment of locally advanced head and neck cancer with misonidazole, hyperbaric oxygen and irradiation: an interim report. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Middle Aged; Misonidazole; Nitroimidazoles; Pilot Projects; Prospective Studies; Radiation-Sensitizing Agents; Random Allocation	1984
Hyperfractionated radiotherapy with or without misonidazole: results of a prospective randomized study in stage III-IV squamous cell carcinoma of the head and neck. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:10 Topics: Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cobalt Radioisotopes; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Prospective Studies; Radiation-Sensitizing Agents; Radioisotope Teletherapy; Radiotherapy Dosage; Random Allocation	1984
Radiation Therapy Oncology Group clinical trials with misonidazole. Cancer, 1981, May-15, Volume: 47, Issue:10 Topics: Brain Neoplasms; Clinical Trials as Topic; Drug Administration Schedule; Glioma; Head and Neck Neoplasms; Humans; Misonidazole; Nausea; Nervous System Diseases; Nitroimidazoles; Radiotherapy Dosage; Random Allocation; Vomiting	1981
A clinical study of hypoxia and metallothionein protein expression in squamous cell carcinomas. Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:3 Topics: Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Metallothionein; Neoplasm Staging; Nitroimidazoles; Proliferating Cell Nuclear Antigen; Protein Precursors; Uterine Cervical Neoplasms	2000
Hypoxia and perfusion measurements in human tumors--initial experience with pimonidazole and IUdR. Acta oncologica (Stockholm, Sweden), 2001, Volume: 40, Issue:8 Topics: Antibodies; Biopsy; Diffusion; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Hypoxia; Idoxuridine; Kinetics; Male; Nitroimidazoles; Nucleic Acid Synthesis Inhibitors; Radiation-Sensitizing Agents; Rectal Neoplasms; Regional Blood Flow; Specimen Handling; Uterine Cervical Neoplasms	2001
A preliminary clinical study in the use of misonidazole in cancer of the head and neck. The British journal of cancer. Supplement, 1978, Volume: 3 Topics: Adult; Aged; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Middle Aged; Nitroimidazoles; Radiation-Sensitizing Agents; Random Allocation	1978
Logistics in designing clinical trials for etanidazole (SR 2508): an RTOG experience. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Etanidazole; Head and Neck Neoplasms; Humans; Nitroimidazoles; Radiation-Sensitizing Agents; Research Design	1992
First analysis of tumor regression for the European randomized trial of etanidazole combined with radiotherapy in head and neck carcinomas. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Etanidazole; Female; Head and Neck Neoplasms; Humans; Male; Nitroimidazoles; Radiation-Sensitizing Agents	1992
Progress report of a phase II and a phase III trial with etanidazole (SR-2508): a multicentre European study. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1991, Volume: 20 Suppl 1 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Evaluation; Etanidazole; Europe; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Radiation-Sensitizing Agents	1991
Clinical trials with etanidazole (SR-2508) by the Radiation Therapy Oncology Group (RTOG). Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1991, Volume: 20 Suppl 1 Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Evaluation; Etanidazole; Head and Neck Neoplasms; Humans; Nitroimidazoles; Radiation-Sensitizing Agents	1991

Other Studies

63 other study(ies) available for azomycin and Head and Neck Neoplasms

Article	Year
Cellular mechanism of action of 2-nitroimidazoles as hypoxia-selective therapeutic agents. Redox biology, 2022, Volume: 52 Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Head and Neck Neoplasms; Hypoxia; Mice; Nitroimidazoles	2022
Imaging of Hypoxic Tumor: Correlation between Diffusion-weighted MR Imaging and Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2020, Aug-03, Volume: 19, Issue:3 Topics: Cell Hypoxia; Diffusion Magnetic Resonance Imaging; Head and Neck Neoplasms; Humans; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals	2020
Hypoxia with 18F-fluoroerythronitroimidazole integrated positron emission tomography and computed tomography (18F-FETNIM PET/CT) in locoregionally advanced head and neck cancer: Hypoxia changes during chemoradiotherapy and impact on clinical outcome. Medicine, 2019, Volume: 98, Issue:40 Topics: Adult; Aged; Aged, 80 and over; Cell Hypoxia; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Radiopharmaceuticals; Survival Analysis; Young Adult	2019
Influence of FAZA PET hypoxia and HPV-status for the outcome of head and neck squamous cell carcinoma (HNSCC) treated with radiotherapy: Long-term results from the DAHANCA 24 trial (NCT01017224). Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2020, Volume: 151 Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Head and Neck Neoplasms; Humans; Hypoxia; Neoplasm Recurrence, Local; Nitroimidazoles; Papillomavirus Infections; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck	2020
Noninvasive Imaging of Cycling Hypoxia in Head and Neck Cancer Using Intrinsic Susceptibility MRI. Clinical cancer research : an official journal of the American Association for Cancer Research, 2017, Aug-01, Volume: 23, Issue:15 Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Contrast Media; Female; Head and Neck Neoplasms; Humans; Lymph Nodes; Magnetic Resonance Imaging; Male; Mice; Neovascularization, Pathologic; Nitroimidazoles; Radiation Tolerance; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Xenograft Model Antitumor Assays	2017
The hypoxia-activated prodrug evofosfamide in combination with multiple regimens of radiotherapy. Oncotarget, 2017, Apr-04, Volume: 8, Issue:14 Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Chemoradiotherapy; Head and Neck Neoplasms; Humans; Mice; Nitroimidazoles; Phosphoramide Mustards; Prodrugs; Radiotherapy	2017
A Novel PET Probe "[ Molecular imaging and biology, 2019, Volume: 21, Issue:1 Topics: Animals; Fluorine Radioisotopes; Glutathione; Head and Neck Neoplasms; Heterografts; Humans; Hypoxia; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nitroimidazoles; Oxidation-Reduction; Oxidative Stress; Positron-Emission Tomography; Tissue Distribution; Tumor Cells, Cultured; Tumor Hypoxia	2019
Optical spectroscopic sensing of tumor hypoxia. Journal of biomedical optics, 2018, Volume: 23, Issue:6 Topics: Animals; Biosensing Techniques; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Hemoglobins; Humans; Mice; Mice, Nude; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Spectrum Analysis; Tumor Cells, Cultured; Tumor Hypoxia	2018
Residual gammaH2AX foci in head and neck squamous cell carcinomas as predictors for tumour radiosensitivity: Evaluation in pre-clinical xenograft models and clinical specimens. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2019, Volume: 137 Topics: Animals; Female; Head and Neck Neoplasms; Histones; Humans; Male; Mice; Nitroimidazoles; Radiation Tolerance; Radiotherapy Dosage; Squamous Cell Carcinoma of Head and Neck; Xenograft Model Antitumor Assays	2019
Impact of Tumour Hypoxia on Evofosfamide Sensitivity in Head and Neck Squamous Cell Carcinoma Patient-Derived Xenograft Models. Cells, 2019, 07-13, Volume: 8, Issue:7 Topics: Animals; Cytochrome P-450 Enzyme System; Head and Neck Neoplasms; Humans; Ki-67 Antigen; Mice; Mice, Inbred NOD; Nitroimidazoles; Nuclear Proteins; Phosphoramide Mustards; Squamous Cell Carcinoma of Head and Neck; Tumor Hypoxia; Xenograft Model Antitumor Assays	2019
PET imaging of tumor hypoxia using 18F-labeled pimonidazole. Acta oncologica (Stockholm, Sweden), 2013, Volume: 52, Issue:7 Topics: Animals; Carcinoma, Squamous Cell; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Hypoxia; Mammary Neoplasms, Animal; Mice; Mice, Inbred C3H; Mice, Nude; Nitroimidazoles; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Tumor Cells, Cultured	2013
A prospective clinical study of ¹⁸F-FAZA PET-CT hypoxia imaging in head and neck squamous cell carcinoma before and during radiation therapy. European journal of nuclear medicine and molecular imaging, 2014, Volume: 41, Issue:8 Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals	2014
Dynamics of tumor hypoxia assessed by 18F-FAZA PET/CT in head and neck and lung cancer patients during chemoradiation: possible implications for radiotherapy treatment planning strategies. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 113, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Hypoxia; Chemoradiotherapy; Cohort Studies; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Radiotherapy Planning, Computer-Assisted; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed	2014
The Effects of Pulsed Radiation Therapy on Tumor Oxygenation in 2 Murine Models of Head and Neck Squamous Cell Carcinoma. International journal of radiation oncology, biology, physics, 2015, Jul-15, Volume: 92, Issue:4 Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Coloring Agents; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Heterografts; Mice; Mice, Nude; Misonidazole; Neoplasm Recurrence, Local; Nitroimidazoles; Oxygen Consumption; Positron-Emission Tomography; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck; Tumor Burden	2015
Assessment of hypoxic subvolumes in laryngeal cancer with (18)F-fluoroazomycinarabinoside ((18)F-FAZA)-PET/CT scanning and immunohistochemistry. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 117, Issue:1 Topics: Aged; Aged, 80 and over; Biomarkers; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypoxia; Laryngeal Neoplasms; Laryngectomy; Male; Middle Aged; Multimodal Imaging; Neoplasm Recurrence, Local; Nitroimidazoles; Pilot Projects; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed	2015
Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs. Cancer research, 2015, Oct-01, Volume: 75, Issue:19 Topics: Activation, Metabolic; Antineoplastic Agents; Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Chemoradiotherapy; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Head and Neck Neoplasms; High-Throughput Screening Assays; Humans; Neoplasm Proteins; Nitroimidazoles; Papillomaviridae; Papillomavirus Infections; Phosphoramide Mustards; Prodrugs; Retrospective Studies; RNA Interference; RNA, Messenger; RNA, Small Interfering; Tirapazamine; Triazines; Tumor Microenvironment; Tumor Stem Cell Assay	2015
Quantitative and qualitative analysis of [(18)F]FDG and [(18)F]FAZA positron emission tomography of head and neck cancers and associations with HPV status and treatment outcome. European journal of nuclear medicine and molecular imaging, 2016, Volume: 43, Issue:4 Topics: Adult; Aged; Data Interpretation, Statistical; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Papillomavirus Infections; Positron-Emission Tomography; Radiopharmaceuticals	2016
Correlation of FMISO simulations with pimonidazole-stained tumor xenografts: A question of O2 consumption? Medical physics, 2016, Volume: 43, Issue:7 Topics: Animals; Benzimidazoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Computer Simulation; Feasibility Studies; Fluorescent Antibody Technique; Head and Neck Neoplasms; Humans; Hypoxia; Mice, Nude; Misonidazole; Models, Biological; Neoplasm Transplantation; Nitroimidazoles; Oxygen Consumption; Platelet Endothelial Cell Adhesion Molecule-1; Tumor Microenvironment	2016
An exploratory study into the role of dynamic contrast-enhanced magnetic resonance imaging or perfusion computed tomography for detection of intratumoral hypoxia in head-and-neck cancer. International journal of radiation oncology, biology, physics, 2009, May-01, Volume: 74, Issue:1 Topics: Aged; Biomarkers, Tumor; Carbonic Anhydrases; Cell Hypoxia; Contrast Media; Female; Head and Neck Neoplasms; Humans; Iohexol; Magnetic Resonance Imaging; Male; Middle Aged; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Statistics, Nonparametric; Tomography, Spiral Computed	2009
PET of hypoxia with 89Zr-labeled cG250-F(ab')2 in head and neck tumors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:7 Topics: Animals; Antibodies, Monoclonal; Autoradiography; Carbonic Anhydrase Inhibitors; Head and Neck Neoplasms; Hypoxia; Image Processing, Computer-Assisted; Immunoglobulin Fab Fragments; Immunoglobulin G; Immunohistochemistry; Isotope Labeling; Mice; Mice, Inbred BALB C; Nitroimidazoles; Organometallic Compounds; Positron-Emission Tomography; Quality Control; Radiation-Sensitizing Agents; Radiopharmaceuticals; Tissue Distribution; Xenograft Model Antitumor Assays; Zirconium	2010
Quantitative assessment of hypoxia kinetic models by a cross-study of dynamic 18F-FAZA and 15O-H2O in patients with head and neck tumors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:9 Topics: Adult; Cell Hypoxia; Feasibility Studies; Female; Head and Neck Neoplasms; Humans; Kinetics; Male; Middle Aged; Models, Biological; Nitroimidazoles; Oxygen Radioisotopes; Positron-Emission Tomography; Reproducibility of Results; Water	2010
Perfusion estimated with rapid dynamic contrast-enhanced magnetic resonance imaging correlates inversely with vascular endothelial growth factor expression and pimonidazole staining in head-and-neck cancer: a pilot study. International journal of radiation oncology, biology, physics, 2011, Nov-15, Volume: 81, Issue:4 Topics: Aged; Algorithms; Carcinoma, Squamous Cell; Cell Hypoxia; Coloring Agents; Contrast Media; Female; Head and Neck Neoplasms; Humans; Kinetics; Magnetic Resonance Imaging; Male; Middle Aged; Models, Biological; Neoplasm Proteins; Neovascularization, Pathologic; Nitroimidazoles; Pilot Projects; Real-Time Polymerase Chain Reaction; Tumor Burden; Vascular Endothelial Growth Factor A	2011
Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4. BMC cancer, 2011, May-12, Volume: 11 Topics: Antigens, Neoplasm; Biomarkers, Tumor; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Cycle Proteins; Cell Hypoxia; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Monocarboxylic Acid Transporters; Muscle Proteins; Neoplasm Staging; Neovascularization, Pathologic; Nitroimidazoles; Oncogene Proteins; Protein Transport; Proteins	2011
Inhibition of tumor lactate oxidation: consequences for the tumor microenvironment. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011, Volume: 99, Issue:3 Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cinnamates; Female; Fluorodeoxyglucose F18; Glucose; Glycolysis; Head and Neck Neoplasms; Immunoenzyme Techniques; Lactates; Linear Models; Luminescent Measurements; Mice; Mice, Nude; Monocarboxylic Acid Transporters; Nitroimidazoles; Oxidation-Reduction; Symporters; Tumor Microenvironment; Uterine Cervical Neoplasms	2011
Expression of EGFR under tumor hypoxia: identification of a subpopulation of tumor cells responsible for aggressiveness and treatment resistance. International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3 Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Disease-Free Survival; ErbB Receptors; Head and Neck Neoplasms; Humans; Nitroimidazoles; Prognosis; Radiation Tolerance; Radiation-Sensitizing Agents	2012
Copper-64-diacetyl-bis(N(4)-methylthiosemicarbazone) pharmacokinetics in FaDu xenograft tumors and correlation with microscopic markers of hypoxia. International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3 Topics: Animals; Autoradiography; Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Coordination Complexes; Head and Neck Neoplasms; Humans; Immunohistochemistry; Muscles; Nitroimidazoles; Organometallic Compounds; Partial Pressure; Radionuclide Imaging; Rats; Rats, Nude; Thiosemicarbazones; Tissue Distribution; Transplantation, Heterologous; Tumor Microenvironment; Xenograft Model Antitumor Assays	2012
¹⁸F-HX4 hypoxia imaging with PET/CT in head and neck cancer: a comparison with ¹⁸F-FMISO. Nuclear medicine communications, 2012, Volume: 33, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Cell Hypoxia; Feasibility Studies; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Tomography, X-Ray Computed; Triazoles	2012
Activation of AKT by hypoxia: a potential target for hypoxic tumors of the head and neck. BMC cancer, 2012, Oct-10, Volume: 12 Topics: Animals; Blotting, Western; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; ErbB Receptors; Fluorescent Antibody Technique; Head and Neck Neoplasms; Heterocyclic Compounds, 3-Ring; Humans; Hypoxia; Mice; Mice, Inbred BALB C; Mice, Nude; Nitroimidazoles; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Radiation-Sensitizing Agents; Radiotherapy; Receptor, ErbB-2; Signal Transduction; Tumor Microenvironment; Xenograft Model Antitumor Assays	2012
HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors. International journal of radiation oncology, biology, physics, 2002, Dec-01, Volume: 54, Issue:5 Topics: Carcinoma, Squamous Cell; Dimerization; Dose-Response Relationship, Drug; Head and Neck Neoplasms; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Idoxuridine; Immunohistochemistry; Ki-67 Antigen; Neovascularization, Pathologic; Nitroimidazoles; Nucleic Acid Synthesis Inhibitors; Perfusion; Transcription Factors; Treatment Outcome	2002
Differentiation-associated staining with anti-pimonidazole antibodies in head and neck tumors. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2004, Volume: 70, Issue:1 Topics: Antibodies, Anti-Idiotypic; Biomarkers; Carcinoma, Squamous Cell; Flow Cytometry; Frozen Sections; Head and Neck Neoplasms; Humans; Hypoxia; NAD(P)H Dehydrogenase (Quinone); NADPH-Ferrihemoprotein Reductase; Nitroimidazoles; Prognosis; Radiation-Sensitizing Agents; Staining and Labeling	2004
Imaging perfusion and hypoxia with PET to predict radiotherapy response in head-and-neck cancer. International journal of radiation oncology, biology, physics, 2004, Jul-15, Volume: 59, Issue:4 Topics: Adult; Aged; Cell Hypoxia; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Radiopharmaceuticals; Tomography, Emission-Computed; Treatment Outcome	2004
Erythropoietin and erythropoietin receptor expression in head and neck cancer: relationship to tumor hypoxia. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Jan-01, Volume: 11, Issue:1 Topics: Disease-Free Survival; Erythropoietin; Head and Neck Neoplasms; Humans; Hypoxia; Immunohistochemistry; Ligands; Nitroimidazoles; Prognosis; Radiation-Sensitizing Agents; Receptors, Erythropoietin; Recombinant Proteins; Time Factors	2005
Comparison of different methods of CAIX quantification in relation to hypoxia in three human head and neck tumor lines. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2005, Volume: 76, Issue:2 Topics: Animals; Antigens, Neoplasm; Benzimidazoles; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Cell Line, Tumor; Head and Neck Neoplasms; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles	2005
Erythropoietin receptor is not a surrogate marker for tumor hypoxia and does not correlate with survival in head and neck squamous cell carcinomas. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2005, Volume: 76, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Male; Middle Aged; Nitroimidazoles; Receptors, Erythropoietin; Survival Rate	2005
Imaging hypoxia after oxygenation-modification: comparing [18F]FMISO autoradiography with pimonidazole immunohistochemistry in human xenograft tumors. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 80, Issue:2 Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Fluorine Radioisotopes; Glioblastoma; Head and Neck Neoplasms; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Radionuclide Imaging	2006
Microsatellite alterations in head and neck squamous cell carcinoma and relation to expression of pimonidazole, CA IX and GLUT-1. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 80, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Base Sequence; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Excitatory Amino Acid Transporter 2; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Loss of Heterozygosity; Male; Microsatellite Instability; Middle Aged; Molecular Sequence Data; Nitroimidazoles	2006
Combined uptake of [18F]FDG and [18F]FMISO correlates with radiation therapy outcome in head-and-neck cancer patients. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 80, Issue:2 Topics: Aged; Cell Hypoxia; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Treatment Outcome	2006
Tumour hypoxia imaging with [18F]FAZA PET in head and neck cancer patients: a pilot study. European journal of nuclear medicine and molecular imaging, 2007, Volume: 34, Issue:10 Topics: Aged; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Oxygen; Pilot Projects; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity	2007
Beyond detection: novel applications for PET imaging to guide cancer therapy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2007, Volume: 48, Issue:6 Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Mammary Neoplasms, Experimental; Nitroimidazoles; Positron-Emission Tomography; Radiation-Sensitizing Agents; Tirapazamine; Triazines	2007
Tumour cell proliferation under hypoxic conditions in human head and neck squamous cell carcinomas. Oral oncology, 2008, Volume: 44, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Biopsy; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Proliferation; Female; Head and Neck Neoplasms; Humans; Idoxuridine; Image Processing, Computer-Assisted; Male; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Nitroimidazoles; Nucleic Acid Synthesis Inhibitors; Radiation-Sensitizing Agents; Treatment Outcome	2008
Identifying and targeting hypoxia in head and neck cancer: a brief overview of current approaches. International journal of radiation oncology, biology, physics, 2007, Volume: 69, Issue:2 Suppl Topics: Antigens, Neoplasm; Biomarkers; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Electrodes; Etanidazole; Head and Neck Neoplasms; Humans; Hydrocarbons, Fluorinated; Intracellular Signaling Peptides and Proteins; Mitochondrial Proteins; Neoplasm Proteins; Nitroimidazoles; Osteopontin; Oxygen; Partial Pressure; Radiation-Sensitizing Agents; Tirapazamine; Triazines	2007
Hypoxia imaging with FAZA-PET and theoretical considerations with regard to dose painting for individualization of radiotherapy in patients with head and neck cancer. International journal of radiation oncology, biology, physics, 2007, Oct-01, Volume: 69, Issue:2 Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Feasibility Studies; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Positron-Emission Tomography; Radiotherapy, Intensity-Modulated; Tomography, X-Ray Computed	2007
Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome: in regard to Evans et al. (Int J Radiat Oncol Biol Phys 2007;69:1024-1031). International journal of radiation oncology, biology, physics, 2008, Apr-01, Volume: 70, Issue:5 Topics: Carbon Dioxide; Carcinoma, Squamous Cell; Cell Hypoxia; Head and Neck Neoplasms; Humans; Nitroimidazoles; Oxygen; Prognosis; Radiation-Sensitizing Agents; Time Factors	2008
Correlation of [18F]FMISO autoradiography and pimonidazole [corrected] immunohistochemistry in human head and neck carcinoma xenografts. European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:10 Topics: Animals; Autoradiography; Biomarkers, Tumor; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Misonidazole; Nitroimidazoles; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity	2008
The use of misonidazole in association with a three-fractions per day regimen in advanced head and neck epidermoid cancer. A pilot study. American journal of clinical oncology, 1983, Volume: 6, Issue:1 Topics: Adult; Aged; Carcinoma, Squamous Cell; Erythema; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Pilot Projects; Radiotherapy Dosage	1983
[Radiosensitization of hypoxic tumor cells with special reference to head and neck cancers]. Wiener klinische Wochenschrift, 1983, Aug-05, Volume: 95, Issue:15 Topics: Half-Life; Head and Neck Neoplasms; Humans; Hypoxia; Misonidazole; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents	1983
The feasibility of high-dose multiple daily fractionation and its combination with anoxic cell sensitizers in the treatment of head and neck cancer. A pilot study of the Radiotherapy Group of the EORTC (European Organisation for Research on Treatment of C International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:10 Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Pilot Projects; Prognosis; Radiotherapy Dosage	1982
Clinical trials of misonidazole in the United States. Cancer clinical trials, 1981, Volume: 4, Issue:1 Topics: Drug Evaluation; Head and Neck Neoplasms; Humans; Misonidazole; Neoplasm Metastasis; Neoplasms; Nervous System Diseases; Nitroimidazoles	1981
Pilot study of radiotherapy with misonidazole in head and neck cancer. Clinical radiology, 1981, Volume: 32, Issue:2 Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nervous System Diseases; Nitroimidazoles; Pilot Projects; Radiotherapy Dosage	1981
Phenytoin-induced changes in the pharmacokinetics of misonidazole in radiotherapy patients. British journal of cancer, 1981, Volume: 44, Issue:4 Topics: Carcinoma, Squamous Cell; Esophageal Neoplasms; Half-Life; Head and Neck Neoplasms; Humans; Kinetics; Misonidazole; Nitroimidazoles; Phenytoin; Time Factors	1981
The value of adjuvant misonidazole in the definitive irradiation of advanced head and neck squamous cancer: an RTOG pilot study (#78-02). International journal of radiation oncology, biology, physics, 1981, Volume: 7, Issue:12 Topics: Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Nausea; Neoplasm Recurrence, Local; Neoplasm Staging; Nitroimidazoles; Paresthesia; Pharyngeal Neoplasms; Prognosis	1981
Multiple daily fractionation (MDF) radiotherapy in association with hyperthermia and/or misonidazole: experimental and clinical results. Cancer, 1980, Jun-01, Volume: 45, Issue:11 Topics: Animals; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Hyperthermia, Induced; Lymphatic Metastasis; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation Dosage; Radiotherapy; Time Factors	1980
[Clinical experience with daily doses of misonidazole (author's transl)]. Strahlentherapie, 1980, Volume: 156, Issue:11 Topics: Adult; Aged; Breast Neoplasms; Female; Genital Neoplasms, Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nervous System; Nitroimidazoles; Time Factors	1980
Imaging tumor hypoxia and tumor perfusion. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1993, Volume: 34, Issue:6 Topics: Brain Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Glioblastoma; Head and Neck Neoplasms; Humans; Iodine Radioisotopes; Lung Neoplasms; Male; Nitroimidazoles; Organotechnetium Compounds; Oximes; Sarcoma; Soft Tissue Neoplasms; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon	1993
Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker. Cancer research, 1998, Sep-01, Volume: 58, Issue:17 Topics: Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Endothelial Growth Factors; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Lymphokines; Nitroimidazoles; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	1998
Vascular architecture and hypoxic profiles in human head and neck squamous cell carcinomas. British journal of cancer, 2000, Volume: 83, Issue:5 Topics: Aged; Biomarkers; Biopsy; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Hypoxia; Image Processing, Computer-Assisted; Immunohistochemistry; Laryngeal Neoplasms; Male; Microscopy, Fluorescence; Middle Aged; Nitroimidazoles; Oropharyngeal Neoplasms; Prognosis	2000
Semiquantitative immunohistochemical analysis for hypoxia in human tumors. International journal of radiation oncology, biology, physics, 2001, Feb-01, Volume: 49, Issue:2 Topics: Calibration; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Nitroimidazoles; Observer Variation; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms	2001
Pharmacokinetics of [18F]FETNIM: a potential marker for PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2001, Volume: 42, Issue:9 Topics: Animals; Dogs; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Hypoxia; Mammary Neoplasms, Experimental; Nitroimidazoles; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tomography, Emission-Computed	2001
Imaging of blood flow and hypoxia in head and neck cancer: initial evaluation with [(15)O]H(2)O and [(18)F]fluoroerythronitroimidazole PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2001, Volume: 42, Issue:11 Topics: Aged; Female; Glucose; Glycolysis; Head and Neck Neoplasms; Humans; Hypoxia; Image Processing, Computer-Assisted; Isotope Labeling; Male; Middle Aged; Muscle, Skeletal; Nitroimidazoles; Oxygen Radioisotopes; Radiopharmaceuticals; Regional Blood Flow; Tomography, Emission-Computed	2001
Prolonged metronidazole administration with protracted radiotherapy: a pilot study on response of advanced tumours. The British journal of cancer. Supplement, 1978, Volume: 3 Topics: Drug Administration Schedule; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Nitroimidazoles; Radiation-Sensitizing Agents; Vomiting	1978
Clinical phase I study of the hypoxic cell radiosensitizer RO-07-0582, a 2-nitroimidazole derivative. Radiology, 1977, Volume: 122, Issue:3 Topics: Chondrosarcoma; Drug Evaluation; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1977
[New results with delayed progression in the cell cycle of solid squamous cell carcinomas of the head-neck area after single and fractionated irradiation with cobalt-60 and neutrons]. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1990, Volume: 166, Issue:11 Topics: Animals; Carcinoma, Squamous Cell; Cell Cycle; Cobalt Radioisotopes; Head and Neck Neoplasms; Neoplasm Transplantation; Neutrons; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors; Transplantation, Heterologous	1990
Late results of multiple fractions per day (MFD) with misonidazole in advanced cancer of the head and neck. A pilot study of the EORTC radiotherapy group. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1985, Volume: 3, Issue:2 Topics: Follow-Up Studies; Head and Neck Neoplasms; Humans; Misonidazole; Neoplasm Staging; Nitroimidazoles; Pilot Projects; Radiotherapy Dosage; Time Factors	1985