Page last updated: 2024-08-21

azomycin and Experimental Neoplasms

azomycin has been researched along with Experimental Neoplasms in 193 studies

Research

Studies (193)

Timeframe	Studies, this research(%)	All Research%
pre-1990	128 (66.32)	18.7374
1990's	33 (17.10)	18.2507
2000's	14 (7.25)	29.6817
2010's	16 (8.29)	24.3611
2020's	2 (1.04)	2.80

Authors

Authors	Studies
Jans, HS; Kumar, P; Wang, M; Wiebe, LI; Wuest, M; Yang, J	1
Kumar, P; Mannan, RH; McEwan, AJ; Wiebe, LI; Xia, H; Zhang, Z	1
Chapman, JD; Iyer, RV; Kim, E; Schneider, RF	1
Minchinton, AI; Stratford, MR	1
Brender, JR; Chandramouli, GVR; Kishimoto, S; Krishna, MC; Mitchell, JB; Saida, Y; Yamamoto, K	1
Cai, K; Chen, Y; He, H; Sun, W; Yin, L; Zhu, R	1
Ager, C; Ai, M; Balasubramanyam, S; Bartkowiak, T; Budhani, P; Curran, MA; Jaiswal, AR; Jayaprakash, P; Li, N; Liu, A; Nicholas, C; Ning, J; Shah, K; Sheng, J; Sun, Y; Wang, G; Zal, A; Zal, T	1
Hua, L; Ju, H; Li, Y; Liu, H; Mao, H; Wang, Z; Xie, Y; Yu, R; Zhao, C; Zhao, L	1
Dietz, C; Erfanzadeh, M; Smith, MB; Wang, L; Yao, X; Zhou, F; Zhu, Q	1
McEwan, AJ; Mercer, JR; Wiebe, LI	1
Belloli, S; Di Grigoli, G; Fazio, F; Masiello, V; Monterisi, C; Moresco, RM; Picchio, M; Sanvito, F; Valtorta, S	1
Saggar, JK; Tannock, IF	1
Chu, T; Lin, X; Luo, R; Luo, Z; Wang, Y; Yang, Z; Zhu, H	1
Feng, F; Higashino, K; Kuge, Y; Masaki, Y; Numata, Y; Shimizu, Y; Yoshioka, T; Zhao, S	1
Cheguillaume, A; De Bast, M; de Groot, T; Gillart, J; Grégoire, V; Haustermans, K; Labar, D; Mahy, P	1
Busk, M; Horsman, MR; Overgaard, J	1
Cui, P; Dai, M; Han, J; Li, H; Liu, Q; Xiu, R; Yu, M; Zhang, J	1
Cecic, IK; Erler, JT; Felsher, D; Giaccia, AJ; Graves, EE; Le, QT; Sayles, L; Sweet-Cordero, A; Tran, PT; Vilalta, M	1
Alsner, J; Busk, M; Horsman, MR; Jakobsen, S; Overgaard, J; Sørensen, BS; Toustrup, K	1
Bussink, J; Dubois, LJ; Janssen, MH; Kolb, HC; Lambin, P; Lieuwes, NG; Ollers, MC; Peeters, WJ; van der Kogel, A; van Dongen, GA; Walsh, JC; Windhorst, AD	1
Bukala, D; Cay, F; Judenhofer, MS; Kneilling, M; Machulla, HJ; Maier, FC; Pichler, BJ; Reischl, G; Röcken, M; Schmid, A	1
Ahluwalia, D; Ammons, WS; Curd, JG; Duan, JX; Ferraro, D; Hart, CP; Liu, Q; Matteucci, MD; Sun, JD; Wang, J; Wang, Y	1
Bol, A; Gallez, B; Grégoire, V; Jordan, B; Labar, D; Magat, J; Mignion, L; Tran, LB	1
Fujii, H; Inoue, K; Kizaka-Kondoh, S; Moriyama, N; Mutou, Y; Saji, H; Ueda, M; Umeda, IO; Yamaguchi, M	1
Grimshaw, R; Honess, DJ; Maxwell, RJ; Raynaud, F; Seddon, BM; Tozer, GM; Workman, P	1
Adomat, H; Bowden, M; Dragowska, W; Gleave, M; Koch, CJ; Skov, K; Woo, J; Yapp, DT	1
Banerjee, S; Mallia, MB; Mathur, A; Sarma, HD; Subramanian, S; Venkatesh, M	1
Baumann, M; Bergmann, R; Beuthien-Baumann, B; Brüchner, K; Dörfler, A; Eicheler, W; Hessel, F; Krause, M; Menegakis, A; Schütze, C; van den Hoff, J; Wüllrich, K; Yaromina, A; Zhou, X; Zips, D	1
Beck, R; Haubner, R; Johnson, TD; Machulla, HJ; Picchio, M; Piert, M; Reischl, G; Schwaiger, M; Seidl, S; Wester, HJ	1
Varghese, AJ; Whitmore, GF	1
Handa, H; Oda, Y; Ono, K; Otsuka, S; Suda, K; Takeuchi, J; Yamashita, J; Yumitori, K	1
Chaplin, DJ; Jinks, S; Millar, BC	1
Brown, JM; Hazlehurst, JL; Hirst, DG	4
Abe, M; Nishidai, T; Ono, K; Shibamoto, Y; Takahashi, M	1
Brown, JM	4
Kehrberg, G; Moldenhauer, H; Rose, H; Saul, G; Wolf, G	1
Brown, JM; Yu, NY	4
Blanke, G; Luscher, G; Streffer, C; Tamulevicius, P	1
Brown, JM; Hazlehurst, JL; Hirst, DG; Horsman, MR	1
Denekamp, J; Fowler, JF; Williams, MV	1
Phillips, TL	2
Brustad, T; Pettersen, EO; Rofstad, EK	1
Brustad, T; Rofstad, EK	3
Ando, K; Furukawa, S; Hiraoka, T; Kanai, T; Kawachi, K; Koike, S; Majima, H	1
Denekamp, J; Rojas, A; Stewart, FA	1
Hunter, N; Ito, H; Milas, L	1
Beach, JL; Grigsby, PW; Mendiondo, OA	1
Adams, GE; Hardy, C; Hoe, S; O'Neill, P; Sheldon, PW; Stratford, IJ	1
Brown, DM; Brown, JM; Lee, WW; Yu, NY	1
Owen, LN; Twentyman, PR; Walton, MI; White, RA; Workman, P	1
de Ronde, J; Hinchliffe, M; McNally, NJ	1
Adams, GE; Ahmed, I; Chaplin, DJ; Sheldon, PW	1
Denekamp, J; Middleton, RW; Minchinton, AI; Rojas, A; Smith, KA; Soranson, JA	1
Chapman, JD; Jette, DC; Wiebe, LI	1
Chapman, JD; Garrecht, BM	1
Brown, DM; Brown, JM; Eifel, PJ; Lee, WW	1
Gibson, P; Sheldon, PW	1
Dembs, NL; Mulcahy, RT; Ublacker, GA	1
Twentyman, PR; Workman, P	1
Lee, FY; Workman, P	1
Blasberg, R; Fenstermacher, J; Horowitz, M; Kornblith, P; Molnar, P; Pleasants, R; Strong, J	1
Csejtey, J; Landahl, HD; Levin, VA; Patlak, CS; Wright, DC	1
Afzal, SM; Curtis, SB; Howard, J; Lyman, JT; Parr, SS; Tenforde, TS	1
Clutterbuck, RD; McElwain, TJ; Millar, JL	1
Chapman, JD; Franko, AJ	1
Freauff, S; Krohn, KA; Rasey, JS	1
Adams, GE; Batten, EL; Sheldon, PW	1
Breur, K; Haveman, J; van den Hoeven, H; van der Schueren, E; Wondergem, J	1
Abratt, RP	1
Glatte, P; Haedecke, U; Osieka, R; Schmidt, CG	1
Aritake, S; Sakamoto, K	1
Courtenay, VD; Mills, J; Peacock, JH; Rose, CM; Spooner, D; Stephens, TC	1
Hampel, N; Persky, L	1
Barratt, GM; Wills, ED	1
Astor, M; Biaglow, JE; Hall, EJ; Varnes, ME	1
Bleehen, NM; Morgan, JE	1
Denekamp, J; Hirst, DG; Stewart, FA; Terry, NH	1
Arcangeli, G; Barocas, A; Mauro, F; Nervi, C; Spanò, M; Tabocchini, A	1
Conroy, PJ; Passalacqua, W; Penney, DP; Sutherland, RM; Von Burg, R	1
Bleehen, NM; Honess, DJ; Morgan, JE; Workman, P	1
Bareham, BJ; Reich, KA; Sutherland, RM	1
Gueulette, J; Guichard, M; Malaise, EP; Octave-Prignot, M; Wambersie, A	1
Denekamp, J	2
Workman, P	3
Allalunis, MJ; Meeker, BE; Pedersen, JE; Turner, AR; Urtasun, RC	1
Catane, R; Clement, JJ; Gorman, MS; Johnson, RK; Wodinsky, I	1
Cherif, A; Gretzer, MB; Kim, EE; Li, C; Podoloff, DA; Wallace, S; Yang, DJ	1
Abe, M; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T; Sugiyama, T	1
Streffer, C; Tamulevicius, P	1
Cline, JM; McEntee, MC; Raleigh, JA; Thrall, DE	1
Bremner, JC	1
el Gamoussi, R; Guichard, M; Prade, M; Stratford, IJ; Threadgill, MD	1
Miyata, Y; Mori, T; Murayama, C; Nishio, A; Sakaguchi, M; Sato, C; Shoji, T; Suzuki, A; Suzuki, T; Tanabe, Y	1
Hodgkiss, RJ; Webster, L; Wilson, GD	2
Abe, M; Hiraoka, M; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T; Takagi, T	1
Ballinger, JR; Kee, JW; Rauth, AM	1
Chapman, JD; Coia, LR; Engelhardt, EL; Fenning, MC; Schneider, RF; Stobbe, CC	1
Aboagye, EO; Graham, MA; Griffiths, JR; Horsman, MR; Kelson, AB; Lewis, AD; Maxwell, RJ; Tracy, M; Workman, P	1
Adams, GE; Butler, SA; Cole, S; Stratford, IJ; Williams, C; Wood, PJ	1
Hori, H; Inayama, S; Inomata, T; Kasai, S; Kuwasaka, H; Nagasawa, H; Nishioka, A; Ogawa, Y; Oshodani, T; Yoshida, S	1
Antoku, S; Ichiya, Y; Maeda, M; Masuda, K; Oka, H; Yamamoto, F	1
Ballinger, JR; Duncan, J; Melo, T; Rauth, AM	1
Kumar, P; Lee, HC; McEwan, AJ; Mercer, JR; Wiebe, LI	1
Busch, TM; Evans, SM; Hahn, SM; Koch, CJ	1
O'Hara, JA; Paulsen, KD; Pogue, BW; Swartz, HM; Wilmot, CM	1
Ando, K; Aoki, M; Furusawa, Y; Kuwabara, Y; Maeda, M; Masuda, K; Sasaki, S; Yamamoto, F	1
Adams, GE; Dische, S; Fowler, JF; Thomlinson, RH	1
Kligerman, MM; Peterson, DF; West, G; Yuhas, JM; Yurconic, M	1
Chapman, JD; Urtasun, RC	1
Denekamp, J; Flockhart, IR; McNally, NJ; Sheldon, P; Stewart, FA	1
Bleehen, NM; Honess, DJ; Morgan, JE	1
Bicknell, RB; Brown, JM; Cory, MJ; Taylor, DL; Yu, NY	1
Peckham, MJ; Stanley, JA; Steel, GG	1
Courtenay, VD; Smith, IE; Steel, GG	1
Fowler, JF; Sheldon, PW	1
Denekamp, J; Stewart, FA	1
Wardman, P	2
Bugden, RD; Peckham, MJ; Pedersen, JE; Smith, MR	1
de Langen-Omri, F; Guichard, M; Malaise, EP	1
Brown, JM; Workman, P; Yu, NY	1
Suwiński, J; Watras, J; Wideł, M	1
Paciga, JE; Rauth, AM	1
Hofer, KG; Hofer, MG; Ieracitano, J; McLaughlin, WH	1
Fowler, JF; Hill, SA	1
Hill, SA; Sheldon, PW	2
Adams, GE; Denekamp, J; Fowler, JF	1
Adams, GE; Fowler, JF	1
Chapman, JD; Mannan, RH; Mercer, JR; Somayaji, VV; Wiebe, LI	1
Hori, H; Inayama, S; Nagasawa, H; Nakajima, T; Onoyama, Y; Tada, T	1
Miyata, Y; Mori, T; Murayama, C; Sakaguchi, M; Sato, C; Shoji, T; Suzuki, A; Suzuki, T; Tanabe, Y	1
Moore, SK; Wallen, CA; Wheeler, KT	1
Adams, GE; Bremner, JC; Cole, S; Edwards, HS; Stratford, IJ	1
Chaplin, DJ; Horsman, MR	1
Anderson, RF; Brown, JM; Denny, WA; Phil, D; Roberts, PB; Wilson, WR	1
Abe, M; Ito, T; Kagiya, VT; Nishimoto, S; Sasai, K; Wang, J	1
Brown, JM; Cribbs, R; Hirst, VK; Luu, YH; Stone, HB	1
Hisanaga, Y; Kagiya, T; Kitakabu, Y; Nishimoto, S; Sasai, K; Shibamoto, Y; Shimokawa, K; Takahashi, M; Wang, J; Zhou, L	1
Chapman, JD; Lee, J; Mannan, RH; Mercer, JR; Somayaji, VV; Wiebe, LI	1
Jin, GY; Li, SJ; Moulder, JE; Raleigh, JA	1
Hodgkiss, RJ; Jones, G; Long, A; Parrick, J; Smith, KA; Stratford, MR; Wilson, GD	1
Jin, GY; Li, SJ; Moulder, JE	1
Wallen, CA; Wheeler, KT; Wong, KH	1
Hirst, DG	1
Coldwell, DM; Coldwell, SG; Huff, J; Marcellus, H	1
Bonnay, M; Guichard, M; Lespinasse, F; Malaise, EP; Thomas, C	1
Howes, AE; Kramer, RA; Montoya, VP; Soble, M	1
Mori, T	1
Miyata, Y; Mori, T; Murayama, C; Sakaguchi, M; Suzuki, A; Suzuki, T; Tanabe, Y; Tanaka, N	1
Mori, T; Murayama, C	2
Abe, M; Hisanaga, Y; Kagiya, T; Nishimoto, S; Sasai, K; Shibamoto, Y; Shimokawa, K; Takahashi, M; Wang, J; Zhou, L	1
Griffiths, JR; Maxwell, RJ; Workman, P	1
Bleehen, NM; Walton, MI; Workman, P	1
Luscher, G; Streffer, C; Tamulevicius, P	1
Chapman, JD; Kanclerz, A	1
Adams, GE; Stratford, IJ	1
Hill, RP	1
Lam, KN; Luu, YH; Stone, HB	1
Biscay, P; Guichard, M; Lespinasse, F; Malaise, EP	1
Bleehen, NM; Honess, DJ; Ward, R; Wasserman, TH; Workman, P	1
Salet, C	1
Walton, MI; Workman, P	1
Baran, LA; Gol'dshmid, BIa; Kurliand, VA; Nonko, VD; Rudakov, NP	1
Abe, M; Kagiya, T; Kimura, R; Nishidai, T; Nishimoto, S; Ono, K; Sakano, K; Shibamoto, Y	1
Allen, PS; Franko, AJ; Lunt, JA; Raleigh, JA; Treiber, EO	1
Agrawal, KC; Rockwell, S; Rupp, WD	1
Abe, M; Hori, H; Inayana, S; Ono, K; Shibamoto, Y; Shibata, T; Takahashi, M	1
Mulcahy, RT; Siemann, DW	1
Chapman, JD; Flanagan, RJ; Jette, DC; Lee, J; Wiebe, LI	1
Born, JL; Franko, AJ; Koch, CJ; Raleigh, JA	1
Blasberg, R; Fenstermacher, J; Horowitz, M; Molnar, P; Owens, E; Patlak, C; Strong, J	1
Chin, L; Grunbaum, Z; Krohn, K; Nelson, N; Rasey, JS	1
Bauer, K; Conroy, PJ; Grunbaum, Z; Krohn, KA; Rasey, JS; Sutherland, RM	1
Bryan, GT; Cohen, SM; Crovetti, AJ; Ertürk, E; Von Esch, AM	1

Reviews

13 review(s) available for azomycin and Experimental Neoplasms

Article	Year
[Intensification of cytostatic action by radiosensitizers--a review of the present status of chemosensitization]. Radiobiologia, radiotherapia, 1984, Volume: 25, Issue:2 Topics: Alkylating Agents; Animals; Antineoplastic Agents; Chlorambucil; Cisplatin; Cricetinae; Cyclophosphamide; Doxorubicin; Etanidazole; Lomustine; Melphalan; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1984
Sensitizers and protectors in clinical oncology. Seminars in oncology, 1981, Volume: 8, Issue:1 Topics: Alkylating Agents; Amifostine; Animals; Drug Synergism; Humans; Mice; Misonidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Organothiophosphorus Compounds; Radiation-Protective Agents; Radiation-Sensitizing Agents	1981
Assessing the bioreductive effectiveness of the nitroimidazole RSU1069 and its prodrug RB6145: with particular reference to in vivo methods of evaluation. Cancer metastasis reviews, 1993, Volume: 12, Issue:2 Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line; Cell Survival; Humans; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxidation-Reduction; Prodrugs; Radiation-Sensitizing Agents	1993
Radiation sensitizers. Cancer, 1976, Volume: 37, Issue:4 Suppl Topics: Animals; Antineoplastic Agents; Bromodeoxycytidine; Bromodeoxyuridine; Carcinoma; Deoxyuridine; Dogs; Dose-Response Relationship, Radiation; Floxuridine; Humans; Hypoxia; Idoxuridine; Lung Neoplasms; Methotrexate; Metronidazole; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Research; Sarcoma, Experimental; Skin	1976
Chemical modification of radiation effects. Cancer, 1977, Volume: 39, Issue:2 Suppl Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Cell Survival; Cysteamine; DNA; Drug Evaluation; Drug Interactions; Humans; Hypoxia; Metronidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Radiation Effects; Radiation-Protective Agents; Radiation-Sensitizing Agents	1977
The use of nitroaromatic compounds as hypoxic cell radiosensitizers. Current topics in radiation research quarterly, 1977, Volume: 11, Issue:4 Topics: Acetophenones; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Neoplasms, Experimental; Nitro Compounds; Nitrobenzenes; Nitrofurans; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Serratia marcescens; Structure-Activity Relationship	1977
[Radiosensitizer: hypoxic cell radiosensitizer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:4 Pt 2-2 Topics: Animals; DNA; Dogs; Etanidazole; Hydroxamic Acids; Hydroxylation; Intercalating Agents; Lethal Dose 50; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Thymine	1989
Micropharmacokinetics of chemical modifiers. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Animals; Cells, Cultured; Flow Cytometry; Humans; Magnetic Resonance Spectroscopy; Mice; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1989
[Present status of radiation sensitizers--hypoxic cell radiosensitizer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:6 Topics: Animals; Hydroxamic Acids; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1989
Hypoxia-mediated nitro-heterocyclic drugs in the radio- and chemotherapy of cancer. An overview. Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1 Topics: Alkylating Agents; Animals; Cell Survival; Drug Synergism; Etanidazole; Hypoxia; Misonidazole; Neoplasms, Experimental; Nitrofurans; Nitrofurazone; Nitroimidazoles; Oxidation-Reduction; Radiation-Sensitizing Agents; Structure-Activity Relationship	1986
Sensitizers and radiation dose fractionation: results and interpretations. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Animals; Combined Modality Therapy; Etanidazole; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Radiotherapy Dosage	1986
Sensitizers and protectors in radiotherapy. Cancer, 1985, May-01, Volume: 55, Issue:9 Suppl Topics: Amifostine; Animals; Aziridines; Clinical Trials as Topic; Drug Evaluation; Etanidazole; Glutathione; Humans; Misonidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy	1985
Hematoporphyrin and hematoporphyrin-derivative photosensitization of mitochondria. Biochimie, 1986, Volume: 68, Issue:6 Topics: Adenosine Triphosphatases; Animals; Biological Transport, Active; Calcium; Cell Line; Electron Transport Complex IV; Hematoporphyrin Derivative; Hematoporphyrins; Lasers; Light; Mitochondria; Mitochondria, Liver; Neoplasms, Experimental; Nitroimidazoles; Oxidative Phosphorylation; Oxygen; Oxygen Consumption; Photochemistry; Rats; Succinate Dehydrogenase	1986

Trials

3 trial(s) available for azomycin and Experimental Neoplasms

Article	Year
Dose-response relationships for human tumors: implications for clinical trials of dose modifying agents. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Animals; Clinical Trials as Topic; Dose-Response Relationship, Radiation; Etanidazole; Humans; Mice; Misonidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1984
Hypoxic cell sensitisers in radiotherapy. Lancet (London, England), 1976, Jan-24, Volume: 1, Issue:7952 Topics: Animals; Clinical Trials as Topic; Drug Evaluation; Drug Evaluation, Preclinical; Humans; Hypoxia; In Vitro Techniques; Mice; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Oxygen Consumption; Radiation-Sensitizing Agents; Radiotherapy Dosage	1976
Sensitizers and protectors in radiotherapy. Cancer, 1985, May-01, Volume: 55, Issue:9 Suppl Topics: Amifostine; Animals; Aziridines; Clinical Trials as Topic; Drug Evaluation; Etanidazole; Glutathione; Humans; Misonidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy	1985

Other Studies

178 other study(ies) available for azomycin and Experimental Neoplasms

Article	Year
In vitro and in vivo evaluation of [(18)F]F-GAZ, a novel oxygen-mimetic azomycin-glucose conjugate, for imaging hypoxic tumor. Cancer biotherapy & radiopharmaceuticals, 2012, Volume: 27, Issue:8 Topics: Animals; Biomimetic Materials; Cell Hypoxia; Female; Fluorodeoxyglucose F18; Glucose; Humans; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Radiopharmaceuticals	2012
[99mTc]Technetium labelled PnAo-azomycin glucuronides: a novel class of imaging markers of tissue hypoxia. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2002, Volume: 57, Issue:5 Topics: Animals; Glucuronides; HeLa Cells; Humans; Hypoxia; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitroimidazoles; Organotechnetium Compounds; Oximes; Radionuclide Imaging; Radiopharmaceuticals; Tumor Cells, Cultured	2002
A dual hypoxic marker technique for measuring oxygenation change within individual tumors. British journal of cancer, 1998, Volume: 78, Issue:2 Topics: Animals; Biomarkers; Cell Hypoxia; Iodine Radioisotopes; Male; Mice; Mice, SCID; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Rats; Rats, Inbred F344	1998
A comparison of tumor and normal tissue levels of acidic, basic and neutral 2-nitroimidazole radiosensitizers in mice. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Animals; Etanidazole; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Tissue Distribution	1986
Hypoxia-Activated Prodrug Evofosfamide Treatment in Pancreatic Ductal Adenocarcinoma Xenografts Alters the Tumor Redox Status to Potentiate Radiotherapy. Antioxidants & redox signaling, 2021, 10-10, Volume: 35, Issue:11 Topics: Animals; Antineoplastic Agents; Carcinoma, Pancreatic Ductal; Cell Hypoxia; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Mice; Neoplasms, Experimental; Nitroimidazoles; Oxidation-Reduction; Pancreatic Neoplasms; Phosphoramide Mustards; Prodrugs	2021
Selective cancer treatment via photodynamic sensitization of hypoxia-responsive drug delivery. Nanoscale, 2018, Feb-08, Volume: 10, Issue:6 Topics: Animals; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Female; Hyaluronic Acid; Hypoxia; Mice, Inbred C57BL; Micelles; Nanoparticles; Neoplasms, Experimental; Nitroimidazoles; Photoacoustic Techniques; Photochemotherapy; Polyethyleneimine; Tissue Distribution	2018
Targeted hypoxia reduction restores T cell infiltration and sensitizes prostate cancer to immunotherapy. The Journal of clinical investigation, 2018, 11-01, Volume: 128, Issue:11 Topics: Adenocarcinoma; Animals; Cell Hypoxia; Cell Line, Tumor; Immunotherapy; Male; Mice; Mice, Knockout; Neoplasm Proteins; Neoplasms, Experimental; Nitroimidazoles; Phosphoramide Mustards; Prostatic Neoplasms; T-Lymphocytes	2018
Design of Tumor Microenvironment-Responsive Drug-Drug Micelle for Cancer Radiochemotherapy. ACS applied materials & interfaces, 2018, Oct-10, Volume: 10, Issue:40 Topics: Animals; Cell Line, Tumor; Chemoradiotherapy; Doxorubicin; Ferrous Compounds; Humans; Hyaluronic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Neoplasms, Experimental; Nitroimidazoles; Tumor Hypoxia; Tumor Microenvironment	2018
Treasure hunt for peptides with undefined chemical modifications: Proteomics identification of differential albumin adducts of 2-nitroimidazole-indocyanine green in hypoxic tumor. Journal of mass spectrometry : JMS, 2020, Volume: 55, Issue:2 Topics: Albumins; Animals; Indocyanine Green; Mice; Neoplasms, Experimental; Nitroimidazoles; Optical Imaging; Peptides; Proteome; Proteomics; Tumor Hypoxia	2020
[131I]IAZA as a molecular radiotherapeutic (MRT) drug: wash-out with cold IAZA accelerates clearance in a murine tumor model. Current radiopharmaceuticals, 2013, Jun-06, Volume: 6, Issue:2 Topics: Animals; Cold Temperature; Healthy Volunteers; Humans; Iodine Radioisotopes; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitroimidazoles; Radiopharmaceuticals; Tissue Distribution	2013
Comparison of 18F-fluoroazomycin-arabinofuranoside and 64Cu-diacetyl-bis(N4-methylthiosemicarbazone) in preclinical models of cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2013, Volume: 54, Issue:7 Topics: Animals; Cell Line, Tumor; Coordination Complexes; Copper Radioisotopes; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Nitroimidazoles; Organ Specificity; Organometallic Compounds; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Thiosemicarbazones; Tissue Distribution	2013
Chemotherapy Rescues Hypoxic Tumor Cells and Induces Their Reoxygenation and Repopulation-An Effect That Is Inhibited by the Hypoxia-Activated Prodrug TH-302. Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, May-01, Volume: 21, Issue:9 Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Docetaxel; Doxorubicin; Female; Humans; Immunohistochemistry; Mice; Mice, Nude; Neoplasms, Experimental; Nitroimidazoles; Phosphoramide Mustards; Prodrugs; Taxoids; Xenograft Model Antitumor Assays	2015
Synthesis and radiolabeling of (64)Cu-labeled 2-nitroimidazole derivative (64)Cu-BMS2P2 for hypoxia imaging. Bioorganic & medicinal chemistry letters, 2016, Mar-01, Volume: 26, Issue:5 Topics: Animals; Cell Hypoxia; Coordination Complexes; Copper Radioisotopes; Isotope Labeling; Lung Neoplasms; Mice; Molecular Imaging; Molecular Structure; Neoplasms, Experimental; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals	2016
Imaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-Nitroimidazole-Based Agent "Pimonidazole" in Hypoxia. PloS one, 2016, Volume: 11, Issue:8 Topics: Animals; Cell Hypoxia; Glutathione; Humans; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Nitroimidazoles	2016
Comparative pharmacokinetics, biodistribution, metabolism and hypoxia-dependent uptake of [18F]-EF3 and [18F]-MISO in rodent tumor models. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2008, Volume: 89, Issue:3 Topics: Animals; Fluorine Radioisotopes; Hypoxia; Male; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiopharmaceuticals; Tissue Distribution	2008
Resolution in PET hypoxia imaging: voxel size matters. Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:7 Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Mice; Mice, Nude; Microscopy, Fluorescence; Necrosis; Neoplasms, Experimental; Nitroimidazoles; Positron-Emission Tomography	2008
Effect of artificial oxygen carrier with chemotherapy on tumor hypoxia and neovascularization. Artificial cells, blood substitutes, and immobilization biotechnology, 2008, Volume: 36, Issue:5 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Cricetinae; HeLa Cells; Hemoglobins; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Mesocricetus; Microvessels; Neoplasms, Experimental; Neovascularization, Pathologic; Nitroimidazoles; Oxygen; Oxygen Inhalation Therapy; Polyethylene Glycols; Tumor Burden	2008
Hypoxia in models of lung cancer: implications for targeted therapeutics. Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Oct-01, Volume: 16, Issue:19 Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Electrodes; Histones; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Proto-Oncogene Proteins c-myc; ras Proteins	2010
In vivo identification and specificity assessment of mRNA markers of hypoxia in human and mouse tumors. BMC cancer, 2011, Feb-09, Volume: 11 Topics: Animals; Biomarkers, Tumor; Carbonic Anhydrases; Cell Line, Tumor; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; Humans; Hypoxia; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Mice, Nude; Neoplasms, Experimental; Nitroimidazoles; Positron-Emission Tomography; Protein-Lysine 6-Oxidase; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transplantation, Heterologous	2011
Preclinical evaluation and validation of [18F]HX4, a promising hypoxia marker for PET imaging. Proceedings of the National Academy of Sciences of the United States of America, 2011, Aug-30, Volume: 108, Issue:35 Topics: Animals; Biomarkers; Cell Hypoxia; Fluorine Radioisotopes; Imidazoles; Male; Neoplasms, Experimental; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Triazoles	2011
Significant impact of different oxygen breathing conditions on noninvasive in vivo tumor-hypoxia imaging using [¹⁸F]-fluoro-azomycinarabino-furanoside ([¹⁸F]FAZA). Radiation oncology (London, England), 2011, Nov-25, Volume: 6 Topics: Animals; Cell Hypoxia; Diagnostic Imaging; Fluorine Radioisotopes; Hypoxia; Image Processing, Computer-Assisted; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Radiopharmaceuticals; Respiration; Ribose	2011
Selective tumor hypoxia targeting by hypoxia-activated prodrug TH-302 inhibits tumor growth in preclinical models of cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Feb-01, Volume: 18, Issue:3 Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Female; Humans; Immunohistochemistry; Mice; Mice, SCID; Neoplasms, Experimental; Neovascularization, Pathologic; Nitroimidazoles; Phosphoramide Mustards; Prodrugs; Xenograft Model Antitumor Assays	2012
Hypoxia imaging with the nitroimidazole 18F-FAZA PET tracer: a comparison with OxyLite, EPR oximetry and 19F-MRI relaxometry. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 105, Issue:1 Topics: Animals; Cell Hypoxia; Fluorine Radioisotopes; Magnetic Resonance Imaging; Male; Neoplasms, Experimental; Nitroimidazoles; Oximetry; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rhabdomyosarcoma	2012
In vivo visualization of heterogeneous intratumoral distribution of hypoxia-inducible factor-1α activity by the fusion of high-resolution SPECT and morphological imaging tests. Journal of biomedicine & biotechnology, 2012, Volume: 2012 Topics: Animals; Female; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Iodine Radioisotopes; Magnetic Resonance Imaging; Mice; Mice, Inbred C3H; Molecular Imaging; Molecular Probes; Neoplasms, Experimental; Nitroimidazoles; Tissue Distribution; Tomography, Emission-Computed, Single-Photon	2012
Validation of the fluorinated 2-nitroimidazole SR-4554 as a noninvasive hypoxia marker detected by magnetic resonance spectroscopy. Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:7 Topics: Animals; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Female; Fluorine Radioisotopes; Hypoxia; Magnetic Resonance Spectroscopy; Mice; Mice, SCID; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Polarography; Rats; Tissue Distribution	2002
Hypoxia in the androgen-dependent Shionogi model for prostate cancer at three stages. Radiation research, 2004, Volume: 162, Issue:5 Topics: Androgens; Animals; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Flow Cytometry; Hypoxia; Image Cytometry; Male; Mammary Neoplasms, Animal; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Nitroimidazoles; Prognosis; Prostatic Neoplasms; Protein Binding; Time Factors; Tumor Burden	2004
A novel [99mTc[triple bond]N]2+ complex of metronidazole xanthate as a potential agent for targeting hypoxia. Bioorganic & medicinal chemistry letters, 2005, Jul-15, Volume: 15, Issue:14 Topics: Animals; Hypoxia; Imidazoles; Ligands; Metronidazole; Mice; Molecular Structure; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals; Structure-Activity Relationship; Time Factors; Tissue Distribution	2005
Experimental evaluation of functional imaging for radiotherapy. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2007, Volume: 183 Spec No 2 Topics: Animals; Biomarkers, Tumor; Dose Fractionation, Radiation; Fluorodeoxyglucose F18; Humans; Mice; Mice, Nude; Neoplasms, Experimental; Neoplastic Stem Cells; Nitroimidazoles; Positron-Emission Tomography; Proportional Hazards Models; Radiation-Sensitizing Agents; Radiopharmaceuticals; Radiotherapy; Radiotherapy Dosage; Xenograft Model Antitumor Assays	2007
Intratumoral spatial distribution of hypoxia and angiogenesis assessed by 18F-FAZA and 125I-Gluco-RGD autoradiography. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2008, Volume: 49, Issue:4 Topics: Animals; Autoradiography; Cell Hypoxia; Female; Fluorine Radioisotopes; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Iodine Radioisotopes; Mice; Neoplasms, Experimental; Neovascularization, Pathologic; Nitroimidazoles; Oligopeptides; Radionuclide Imaging	2008
Binding to cellular macromolecules as a possible mechanism for the cytotoxicity of misonidazole. Cancer research, 1980, Volume: 40, Issue:7 Topics: Ammonium Chloride; Animals; Cricetinae; Cricetulus; DNA; Female; Injections, Intraperitoneal; Macromolecular Substances; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Ovary; Oxidation-Reduction; RNA; Serum Albumin, Bovine; Zinc	1980
[Radiosensitizing effect of misonidazole on intracranially transplanted tumors in mice and its clinical application (author's transl)]. Neurologia medico-chirurgica, 1982, Volume: 22, Issue:5 Topics: Adult; Aged; Animals; Brain Neoplasms; Cobalt Radioisotopes; Female; Glioma; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy Dosage	1982
Studies on the protection against misonidazole-induced toxicity by antiinflammatory agents. Advances in prostaglandin, thromboxane, and leukotriene research, 1983, Volume: 12 Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dexamethasone; Female; Flurbiprofen; Lung; Lung Neoplasms; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Phospholipases; Phospholipases A; Propionates	1983
Sensitization of normal and malignant tissue to cyclophosphamide by nitroimidazoles with different partition coefficients. British journal of cancer, 1984, Volume: 49, Issue:1 Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Etanidazole; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1984
[Recent advances in hypoxic cell radiosensitizer]. Gan no rinsho. Japan journal of cancer clinics, 1983, Volume: 29, Issue:13 Topics: Animals; Cells, Cultured; Etanidazole; Maleates; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Oxygen Consumption; Radiation-Sensitizing Agents	1983
Clinical trials of radiosensitizers: what should we expect? International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:3 Topics: Animals; Cell Line; Cell Survival; Cricetinae; Dogs; Dose-Response Relationship, Drug; Drug Evaluation; Drug Evaluation, Preclinical; Etanidazole; Humans; Kinetics; Lethal Dose 50; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1984
Radiosensitization of hypoxic cells in vivo by SR 2508 at low radiation doses: a preliminary report. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Combined Modality Therapy; Dose-Response Relationship, Radiation; Etanidazole; Female; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1984
Depletion of glutathione in vivo as a method of improving the therapeutic ratio of misonidazole and SR 2508. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Buthionine Sulfoximine; Combined Modality Therapy; Etanidazole; Glutathione; Maleates; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1984
The effects of radiosensitizers on intermediary metabolism in vivo. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenocarcinoma; Animals; Dihydroxyacetone Phosphate; Etanidazole; Glycerophosphates; Hydroxybutyrates; Lactates; Liver; Male; Mice; Mice, Inbred Strains; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Pyruvates; Radiation-Sensitizing Agents	1984
The effect of timing on chemosensitization by clinical levels of SR-2508. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Etanidazole; Melphalan; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1984
Sensitising effect of misonidazole on NHIK 1922 cells irradiated in vitro or as solid tumour in athymic nude mice. Acta radiologica. Oncology, 1981, Volume: 20, Issue:2 Topics: Animals; Cell Line; Cell Survival; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Hypoxia; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Protective Agents	1981
Broad-shouldered survival curves of a human melanoma xenograft. Implications for radiation therapy in the absence and presence of misonidazole. Acta radiologica. Oncology, 1981, Volume: 20, Issue:4 Topics: Animals; Humans; Melanoma; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Prognosis; Radiation-Sensitizing Agents; Transplantation, Heterologous	1981
[Biological studies of proton irradiation under combination with a hypoxic cell sensitizer]. Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1982, Apr-25, Volume: 42, Issue:4 Topics: Animals; Carcinoma, Squamous Cell; Female; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Protons; Radiotherapy, High-Energy; Skin Neoplasms	1982
Interaction of misonidazole and WR-2721--II. Modification of tumour radiosensitization. British journal of cancer, 1983, Volume: 47, Issue:1 Topics: Amifostine; Animals; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Fibrosarcoma; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Organothiophosphorus Compounds; Radiation Tolerance; Sarcoma, Experimental	1983
Effect of tumor size on S-2-(3-aminopropylamino)ethylphosphorothioic acid and misonidazole alteration of tumor response to cyclophosphamide. Cancer research, 1983, Volume: 43, Issue:7 Topics: Amifostine; Animals; Cyclophosphamide; Drug Interactions; Drug Therapy, Combination; Extremities; Female; Fibrosarcoma; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Organothiophosphorus Compounds; Time Factors	1983
Radioprotection combined with hypoxic sensitization during radiotherapy of a solid murine tumor. Radiology, 1983, Volume: 148, Issue:1 Topics: Amifostine; Animals; Cell Line; Dose-Response Relationship, Drug; Drug Interactions; Female; Mice; Mice, Inbred BALB C; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Organothiophosphorus Compounds; Oxygen; Radiotherapy Dosage; Statistics as Topic	1983
Thiol reactive nitroimidazoles: radiosensitization studies in vitro and in vivo. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1984, Volume: 46, Issue:6 Topics: Animals; Cells, Cultured; Combined Modality Therapy; Cricetinae; Cricetulus; Dithiothreitol; Glutathione; Mice; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1984
SR-2508: a 2-nitroimidazole amide which should be superior to misonidazole as a radiosensitizer for clinical use. International journal of radiation oncology, biology, physics, 1981, Volume: 7, Issue:6 Topics: Animals; Carcinoma; Cell Line; Central Nervous System; Cricetinae; Dogs; Etanidazole; Female; In Vitro Techniques; Lipid Metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Sarcoma, Experimental; X-Rays	1981
Preclinical pharmacokinetics of benznidazole. British journal of cancer, 1984, Volume: 50, Issue:3 Topics: Animals; Antineoplastic Agents; Brain; Chromatography, High Pressure Liquid; Dogs; Drug Evaluation, Preclinical; Female; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitroimidazoles; Pharmaceutical Vehicles; Sheep	1984
The effect of prolonged high dose misonidazole on tumor response to radiation. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Combined Modality Therapy; Dose-Response Relationship, Radiation; Mice; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1984
Potentiation of cyclophosphamide cytotoxicity in vivo: a study with misonidazole and fifteen other 1-substituted 2-nitroimidazoles. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1984
Enhancement of misonidazole radiosensitization by buthionine sulphoximine. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1984, Volume: 2, Issue:4 Topics: Animals; Buthionine Sulfoximine; Combined Modality Therapy; Dose-Response Relationship, Radiation; Drug Synergism; Glutathione; Methionine Sulfoximine; Mice; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Skin	1984
Electron-affinic compounds for labelling hypoxic cells: the synthesis and characterization of 1-[2-(2-iodophenoxy)-ethyl]-2-nitroimidazole. Nuklearmedizin. Nuclear medicine, 1984, Volume: 23, Issue:2 Topics: Animals; Male; Mice; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radionuclide Imaging; Tissue Distribution	1984
The labelling of EMT-6 tumours in BALB/C mice with 14C-misonidazole. The British journal of radiology, 1983, Volume: 56, Issue:670 Topics: Animals; Autoradiography; Carbon Radioisotopes; Female; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen Consumption; Time Factors; Tissue Distribution	1983
Misonidazole neurotoxicity in mice decreased by administration with pyridoxine. International journal of radiation oncology, biology, physics, 1983, Volume: 9, Issue:10 Topics: Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Female; In Vitro Techniques; Kinetics; Mice; Mice, Inbred BALB C; Misonidazole; Neoplasms, Experimental; Nervous System; Nitroimidazoles; Pyridoxine; Schiff Bases; Time Factors	1983
Effect of partition coefficient on the ability of nitroimidazoles to enhance the cytotoxicity of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea. Cancer research, 1983, Volume: 43, Issue:5 Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Hematopoietic Stem Cells; Injections, Intraperitoneal; Lomustine; Male; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Nitrosourea Compounds; Solubility; Spermatogonia	1983
Effect of the nitroimidazole Ro 03-8799 on the activity of chemotherapeutic agents against a murine tumour in vivo. British journal of cancer, 1984, Volume: 49, Issue:3 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitroimidazoles; Tumor Stem Cell Assay	1984
Enhancement of nitrosourea cytotoxicity by misonidazole in vitro: correlation with carbamoylating potential. British journal of cancer, 1984, Volume: 49, Issue:3 Topics: Alkylating Agents; Animals; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Nitrosourea Compounds; Oxygen; Structure-Activity Relationship	1984
An investigation of the possibility of chemosensitization by clinically achievable concentrations of misonidazole. British journal of cancer, 1983, Volume: 47, Issue:2 Topics: Animals; Antineoplastic Agents; Cell Division; Drug Therapy, Combination; Female; Male; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen	1983
Modification of CCNU pharmacokinetics by misonidazole--a major mechanism of chemosensitization in mice. British journal of cancer, 1983, Volume: 47, Issue:5 Topics: Animals; Blood Proteins; Cell Line; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Female; Half-Life; Kinetics; Lomustine; Male; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Nitrosourea Compounds	1983
Regional [14C]misonidazole distribution in experimental RT-9 brain tumors. Cancer research, 1983, Volume: 43, Issue:8 Topics: Animals; Autoradiography; Brain Neoplasms; Cerebrovascular Circulation; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Rats; Rats, Inbred F344; Regional Blood Flow; Tissue Distribution	1983
In situ drug delivery. The British journal of cancer. Supplement, 1980, Volume: 4 Topics: Animals; Capillaries; Carmustine; Half-Life; Misonidazole; Models, Biological; Neoplasms, Experimental; Nitroimidazoles; Rats	1980
Increased enhancement of tumour response to X-rays and high-LET neon ions by desmethylmisonidazole relative to misonidazole. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1982, Volume: 41, Issue:6 Topics: Animals; Dose-Response Relationship, Radiation; Energy Transfer; Misonidazole; Neon; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Rats; Rhabdomyosarcoma; X-Rays	1982
Misonidazole enhancement of the action of BCNU and melphalan against human melanoma xenografts. American journal of clinical oncology, 1982, Volume: 5, Issue:1 Topics: Animals; Antineoplastic Agents; Bone Marrow; Carmustine; Cell Line; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Melanoma; Melphalan; Mice; Mice, Inbred CBA; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Transplantation, Heterologous	1982
Binding of 14C-misonidazole to hypoxic cells in V79 spheroids. British journal of cancer, 1982, Volume: 45, Issue:5 Topics: Autoradiography; Binding Sites; Cells, Cultured; Dose-Response Relationship, Drug; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Time Factors	1982
Bromomisonidazole: synthesis and characterization of a new radiosensitizer. Radiation research, 1982, Volume: 91, Issue:3 Topics: Animals; Cell Survival; Dose-Response Relationship, Radiation; Female; Half-Life; Injections, Intraperitoneal; Injections, Intravenous; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Tissue Distribution	1982
Potentiation of melphalan activity against a murine tumour by nitroimidazole compounds. British journal of cancer, 1982, Volume: 46, Issue:4 Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Male; Melphalan; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitroimidazoles	1982
Effect of hyperthermia and misonidazole on the radiosensitivity of a transplantable murine tumor: influence of factors modifying the fraction of hypoxic cells. International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:8 Topics: Anesthesia; Animals; Dose-Response Relationship, Radiation; Hot Temperature; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation Tolerance	1982
A new approach to the use of misonidazole as a radiosensitizer of hypoxic tumour cells. British journal of cancer, 1982, Volume: 46, Issue:6 Topics: Animals; Cell Survival; Dose-Response Relationship, Radiation; Humans; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiotherapy Dosage; Urinary Bladder Neoplasms	1982
[Enhancement of MeCCNU potency (chemosensitization) by misonidazole in a human melanoma xenograft system]. Strahlentherapie, 1982, Volume: 158, Issue:10 Topics: Animals; Cell Line; Drug Interactions; Female; Humans; Melanoma; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Nitrosourea Compounds; Semustine	1982
Effects of misonidazole on tumor cell radiation sensitivity and potentially lethal damage repair in vivo and in vitro. European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:7 Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation Tolerance; Time Factors	1981
Enhancement of CCNU cytotoxicity by misonidazole: possible therapeutic gain. British journal of cancer, 1982, Volume: 46, Issue:1 Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Hematopoietic Stem Cells; Lomustine; Male; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Nitrosourea Compounds; Spermatogonia; Time Factors	1982
Enhanced cell killing in lewis lung carcinoma and a human pancreatic-carcinoma xenograft by the combination of cytotoxic drugs and misonidazole. British journal of cancer, 1981, Volume: 43, Issue:4 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Survival; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Pancreatic Neoplasms; Transplantation, Heterologous	1981
Influence of misonidazole on the radiosensitivity of transplantable transitional cell bladder carcinoma in mice. Investigative urology, 1981, Volume: 19, Issue:1 Topics: Animals; Carcinoma, Transitional Cell; Dose-Response Relationship, Radiation; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Prognosis; Radiation-Sensitizing Agents; Urinary Bladder Neoplasms	1981
Effects of misonidazole, irradiation and hyperthermia on lysosomal enzyme activity in mouse tumours. European journal of cancer, 1981, Volume: 17, Issue:1 Topics: Acid Phosphatase; Animals; Body Temperature; Cell Membrane Permeability; Glucuronidase; Hot Temperature; Lysosomes; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Time Factors	1981
Mechanism of misonidazole-linked cytotoxicity and altered radiation response: role of cellular thiols. The British journal of radiology, 1981, Volume: 54, Issue:647 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation Tolerance; Sulfhydryl Compounds	1981
Interactions between misonidazole and hyperthermia in EMT6 spheroids. British journal of cancer, 1981, Volume: 44, Issue:6 Topics: Cell Survival; Cells, Cultured; Hot Temperature; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Time Factors	1981
Is tumour radiosensitization by misonidazole a general phenomenon? British journal of cancer, 1980, Volume: 41, Issue:1 Topics: Animals; Carcinoma; Cell Line; Dose-Response Relationship, Radiation; Male; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation Tolerance; Sarcoma, Experimental; Time Factors	1980
Multiple daily fractionation (MDF) radiotherapy in association with hyperthermia and/or misonidazole: experimental and clinical results. Cancer, 1980, Jun-01, Volume: 45, Issue:11 Topics: Animals; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Hyperthermia, Induced; Lymphatic Metastasis; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation Dosage; Radiotherapy; Time Factors	1980
Effect of acute and chronic misonidazole administration on peripheral-nerve electrophysiology in mice. British journal of cancer, 1980, Volume: 41, Issue:4 Topics: Animals; Drug Administration Schedule; Female; Mice; Misonidazole; Neoplasms, Experimental; Neural Conduction; Nitroimidazoles; Sural Nerve; Tibial Nerve	1980
Effects of local hyperthermia on the pharmacokinetics of misonidazole in the anaesthetized mouse. British journal of cancer, 1980, Volume: 41, Issue:4 Topics: Abdomen; Anesthesia; Animals; Drug Administration Schedule; Drug Interactions; Half-Life; Hindlimb; Hot Temperature; Male; Mice; Mice, Inbred BALB C; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Pentobarbital; Transplantation, Homologous	1980
Cytotoxicity of hypoxic cell sensitizers in multicell spheroids. Cancer clinical trials, 1980,Spring, Volume: 3, Issue:1 Topics: Animals; Autoradiography; Cell Count; Cell Cycle; Cells, Cultured; Dose-Response Relationship, Drug; Doxorubicin; Kinetics; Mice; Neoplasms, Experimental; Nitroimidazoles; Oxygen	1980
Effect of combined misonidazole and d(50)-Be neutrons on a human melanoma transplanted into nude mice. Radiology, 1980, Volume: 136, Issue:2 Topics: Animals; Cell Line; Cell Survival; DNA Repair; Fast Neutrons; Half-Life; Humans; Injections, Intraperitoneal; Melanoma; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Neutrons; Nitroimidazoles; Radiotherapy Dosage; Time Factors; Transplantation, Heterologous	1980
Testing of hypoxic cell radiosensitizers in vivo. Cancer clinical trials, 1980,Summer, Volume: 3, Issue:2 Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Humans; Hypoxia; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1980
The optimum time for irradiation relative to tumour concentration of hypoxic cell sensitizers. The British journal of radiology, 1980, Volume: 53, Issue:633 Topics: Animals; Cell Survival; Kinetics; Metronidazole; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1980
Dose-dependence and related studies on the pharmacokinetics of misonidazole and desmethylmisonidazole in mice. Cancer chemotherapy and pharmacology, 1980, Volume: 5, Issue:1 Topics: Animals; Biological Availability; Body Temperature; Dose-Response Relationship, Drug; Female; Half-Life; Kinetics; Male; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Phenobarbital; Premedication; Sex Factors; Skin Neoplasms	1980
Cytotoxic and radiosensitizing effects of misonidazole on hematopoiesis in normal and tumor-bearing mice. International journal of radiation oncology, biology, physics, 1980, Volume: 6, Issue:9 Topics: Animals; Colony-Forming Units Assay; Dose-Response Relationship, Radiation; Hematopoiesis; Hematopoietic Stem Cells; Hypoxia; Lung Neoplasms; Male; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles	1980
Enhancement of antitumor activity of alkylating agents by the radiation sensitizer misonidazole. Cancer research, 1980, Volume: 40, Issue:11 Topics: Alkylating Agents; Animals; Aziridines; Benzoquinones; Cyclohexenes; Cyclophosphamide; Drug Therapy, Combination; Female; Melphalan; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Quinones; Semustine	1980
Development of F-18-labeled fluoroerythronitroimidazole as a PET agent for imaging tumor hypoxia. Radiology, 1995, Volume: 194, Issue:3 Topics: Animals; Autoradiography; Cell Hypoxia; Contrast Media; Female; Fluorine Radioisotopes; Male; Mammary Neoplasms, Experimental; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Rabbits; Rats; Rats, Inbred F344; Tissue Distribution; Tomography, Emission-Computed	1995
Combined cytokinesis-block micronucleus and chromosomal aberration assay for the evaluation of radiosensitizers at low radiation doses. International journal of radiation oncology, biology, physics, 1994, Dec-01, Volume: 30, Issue:5 Topics: Aerobiosis; Animals; Cell Line; Chromosome Aberrations; Dose-Response Relationship, Radiation; Etanidazole; Female; Mice; Mice, Inbred BALB C; Micronucleus Tests; Mutagenicity Tests; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1994
Metabolic studies and neurotoxicity in tumors and brain of mice after hypoxic cell sensitizers. International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3 Topics: Adenosine Triphosphate; Animals; Brain; Etanidazole; Glucose; Male; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents	1994
ELISA quantification of CCI-103F binding in canine tumors prior to and during irradiation. International journal of radiation oncology, biology, physics, 1994, Feb-01, Volume: 28, Issue:3 Topics: Animals; Cell Hypoxia; Dogs; Enzyme-Linked Immunosorbent Assay; Neoplasms, Experimental; Nitroimidazoles	1994
Relationship between the melanin content of a human melanoma cell line and its radiosensitivity and uptake of pimonidazole. Cancer chemotherapy and pharmacology, 1993, Volume: 31, Issue:4 Topics: Animals; Autoradiography; Cell Line; Etanidazole; Humans; Melanins; Melanoma; Mice; Mice, Nude; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1993
Radiosensitization by a new potent nucleoside analog: 1-(1',3',4'-trihydroxy-2'-butoxy)methyl-2-nitroimidazole(RP-343). International journal of radiation oncology, biology, physics, 1993, Jun-15, Volume: 26, Issue:3 Topics: Animals; Cell Hypoxia; Cell Survival; Dogs; Dose-Response Relationship, Drug; Etanidazole; Female; In Vitro Techniques; Injections, Intravenous; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents	1993
Simultaneous triple staining for hypoxia, proliferation, and DNA content in murine tumours. Cytometry, 1995, Dec-01, Volume: 21, Issue:4 Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Hypoxia; DNA, Neoplasm; Flow Cytometry; Immunohistochemistry; Male; Mice; Mice, Inbred CBA; Neoplasms, Experimental; Nitroimidazoles; Predictive Value of Tests; S Phase; Staining and Labeling; Theophylline; Tumor Cells, Cultured	1995
Comparison of in vivo efficacy of hypoxic cytotoxin tirapazamine and hypoxic cell radiosensitizer KU-2285 in combination with single and fractionated irradiation. Japanese journal of cancer research : Gann, 1996, Volume: 87, Issue:1 Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Radiotherapy Dosage; Tirapazamine; Triazines	1996
In vitro and in vivo evaluation of a technetium-99m-labeled 2-nitroimidazole (BMS181321) as a marker of tumor hypoxia. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:6 Topics: Animals; Cell Hypoxia; CHO Cells; Cricetinae; Drug Evaluation, Preclinical; In Vitro Techniques; Male; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Organotechnetium Compounds; Oxygen; Radionuclide Imaging; Technetium; Tissue Distribution; Tumor Cells, Cultured	1996
Prediction of tumour hypoxia and radioresistance with nuclear medicine markers. The British journal of cancer. Supplement, 1996, Volume: 27 Topics: Animals; Cell Hypoxia; Mice; Mice, SCID; Neoplasms, Experimental; Nitroimidazoles; Radiation Tolerance; Rats; Tomography, Emission-Computed, Single-Photon	1996
Preclinical evaluation of the fluorinated 2-nitroimidazole N-(2-hydroxy-3,3,3-trifluoropropyl)-2-(2-nitro-1-imidazolyl) acetamide (SR-4554) as a probe for the measurement of tumor hypoxia. Cancer research, 1997, Aug-01, Volume: 57, Issue:15 Topics: Animals; Carbon Dioxide; Cell Hypoxia; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Female; Fluorine; Hydralazine; Injections, Intraperitoneal; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Reproducibility of Results	1997
Enhancement of bioreductive drug toxicity in murine tumours by inhibition of the activity of nitric oxide synthase. British journal of cancer, 1997, Volume: 76, Issue:4 Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Survival; Drug Synergism; Enzyme Inhibitors; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitric Oxide Synthase; Nitroarginine; Nitroimidazoles	1997
Cell cycle distribution of hypoxia and progression of hypoxic tumour cells in vivo. British journal of cancer, 1998, Volume: 77, Issue:2 Topics: Adenocarcinoma; Animals; Bromodeoxyuridine; Cell Cycle; Cell Division; DNA, Neoplasm; Flow Cytometry; Hypoxia; Mice; Neoplasms, Experimental; Nitroimidazoles; Sarcoma, Experimental; Theophylline	1998
TX-1877: design, synthesis, and biological activities as a BRM-functional hypoxic cell radiosensitizer. International journal of radiation oncology, biology, physics, 1998, Nov-01, Volume: 42, Issue:4 Topics: Animals; Cell Hypoxia; Drug Design; Female; Immunologic Factors; Lung Neoplasms; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1998
Synthesis and characterization of lipophilic 1-[18F]fluoroalkyl-2-nitroimidazoles for imaging hypoxia. Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:6 Topics: Animals; Brain; Female; Fluorine Radioisotopes; Hypoxia; Imidazoles; Male; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitro Compounds; Nitroimidazoles; Radionuclide Imaging; Rats; Rats, Wistar; Solubility; Tissue Distribution	1999
BRU59-21, a second-generation 99mTc-labeled 2-nitroimidazole for imaging hypoxia in tumors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2000, Volume: 41, Issue:1 Topics: Animals; Cell Hypoxia; CHO Cells; Cricetinae; Female; Imidazoles; Male; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution	2000
Synthesis, radiolabeling, and biodistribution of putative metabolites of iodoazomycin arabinoside. Nuclear medicine and biology, 2000, Volume: 27, Issue:1 Topics: Animals; Injections, Intravenous; Iodine Radioisotopes; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitroimidazoles; Radionuclide Imaging; Tissue Distribution	2000
Depletion of tumor oxygenation during photodynamic therapy: detection by the hypoxia marker EF3 [2-(2-nitroimidazol-1[H]-yl)-N-(3,3,3-trifluoropropyl)acetamide ]. Cancer research, 2000, May-15, Volume: 60, Issue:10 Topics: Animals; Cell Separation; Fibrosarcoma; Flow Cytometry; Mice; Microscopy, Fluorescence; Molecular Probes; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Nitroimidazoles; Oxygen Consumption; Photochemotherapy; Tumor Cells, Cultured	2000
Estimation of oxygen distribution in RIF-1 tumors by diffusion model-based interpretation of pimonidazole hypoxia and eppendorf measurements. Radiation research, 2001, Volume: 155, Issue:1 Pt 1 Topics: Animals; Cell Hypoxia; Data Interpretation, Statistical; Diffusion; Female; Fibrosarcoma; Kinetics; Mice; Models, Biological; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Nitroimidazoles; Oxygen; Oxygen Consumption; Partial Pressure; Radiation-Sensitizing Agents; Staining and Labeling	2001
Synthesis and evaluation of 4-bromo-1-(3-[18F]fluoropropyl)-2-nitroimidazole with a low energy LUMO orbital designed as brain hypoxia-targeting imaging agent. Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:5 Topics: Animals; Biotransformation; Chemical Phenomena; Chemistry, Physical; CHO Cells; Cricetinae; Electrons; Fluorine Radioisotopes; Hypoxia, Brain; Lipids; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Tissue Distribution	2002
Combined use of radioprotective and radiosensitizing drugs in experimental radiotherapy. Radiation research, 1977, Volume: 70, Issue:2 Topics: Amifostine; Animals; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Drug Therapy, Combination; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitroimidazoles; Organothiophosphorus Compounds; Radiation-Protective Agents; Radiation-Sensitizing Agents; Time Factors	1977
The application in radiation therapy of substances which modify cellular radiation response. Cancer, 1977, Volume: 40, Issue:1 Suppl Topics: Amifostine; Animals; Drug Evaluation; Drug Therapy, Combination; Humans; Metronidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Oxygen Consumption; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy Dosage	1977
Radiosensitization by misonidazole (Ro 07-0582). The importance of timing and tumor concentration of sensitizer. Radiation research, 1978, Volume: 73, Issue:3 Topics: Animals; Female; Fibrosarcoma; Male; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Osteosarcoma; Oxygen; Radiation-Sensitizing Agents; Time Factors; Transplantation, Isogeneic	1978
The hyperthermic potentiation of the cytotoxic effect of misonidazole on the EMT6 mouse tumour: relevance of in vitro measurement of in vivo effect. The British journal of cancer. Supplement, 1978, Volume: 3 Topics: Animals; Cell Survival; Hot Temperature; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitroimidazoles; Time Factors	1978
In vivo evaluation of the radiosensitizing and cytotoxic properties of newly synthesized electron-affinic drugs. The British journal of cancer. Supplement, 1978, Volume: 3 Topics: Animals; Cell Survival; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitroimidazoles; Octanols; Radiation-Sensitizing Agents; Solubility; Time Factors	1978
Influence of tumour size on radiosensitization by misonidazole. The British journal of cancer. Supplement, 1978, Volume: 3 Topics: Animals; Cell Survival; Lung Neoplasms; Melanoma; Mice; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1978
The effect of misonidazole on the radiation response of clonogenic human pancreatic carcinoma cells. The British journal of cancer. Supplement, 1978, Volume: 3 Topics: Animals; Cell Survival; Humans; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Pancreatic Neoplasms; Radiation-Sensitizing Agents; Time Factors; Transplantation, Heterologous	1978
Radiosensitization by misonidazole (Ro-07-0582) of fractionated X-rays in a murine tumour. The British journal of cancer. Supplement, 1978, Volume: 3 Topics: Animals; Mice; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Radiotherapy Dosage; Skin	1978
Sensitization of mouse tumours using fractionated X-irradiation. The British journal of cancer. Supplement, 1978, Volume: 3 Topics: Animals; Mice; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Radiotherapy Dosage	1978
Distribution and tumour cytotoxicity of the radiosensitizer misonidazole (Ro-07-0582) in C57 mice. British journal of cancer, 1979, Volume: 39, Issue:4 Topics: Animals; Cell Survival; Guinea Pigs; Lung Neoplasms; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Tissue Distribution	1979
Radiosensitizing effect of misonidazole in fractionated gamma-ray treatment of a human malignant melanoma grown in athymic nude mice. The British journal of radiology, 1979, Volume: 52, Issue:617 Topics: Animals; Gamma Rays; Humans; Male; Melanoma; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiotherapy Dosage; Time Factors; Transplantation, Heterologous	1979
Influence of misonidazole on the radiosensitivity of a human melanoma in nude mice: time-dependent increase in surviving fraction. International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:4 Topics: Animals; Cell Survival; Female; Humans; Hypoxia; In Vitro Techniques; Melanoma; Mice; Mice, Nude; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Time Factors	1979
Pharmacokinetic considerations in testing hypoxic cell radiosensitizers in mouse tumours. British journal of cancer, 1979, Volume: 39, Issue:3 Topics: Animals; Female; Half-Life; Kidney; Ligation; Mice; Mice, Inbred BALB C; Misonidazole; Neoplasms, Experimental; Nephrectomy; Nitroimidazoles; Radiation-Sensitizing Agents	1979
Effects of pretreatment with phenobarbitone and phenytoin on the pharmacokinetics and toxicity of phenytoin on the pharmacokinetics and toxicity of misonidazole in mice. British journal of cancer, 1979, Volume: 40, Issue:3 Topics: Animals; Body Temperature; Body Weight; Brain; Drug Interactions; Half-Life; Lethal Dose 50; Liver; Male; Mice; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Phenobarbital; Phenytoin; Sleep; Transplantation, Homologous	1979
Response of the solid Guerin epitheliomas of rats to fractionated irradiation and a new 4-nitroimidazole. British journal of cancer, 1979, Volume: 40, Issue:3 Topics: Animals; Carcinoma, Squamous Cell; Male; Metronidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Rats; Rats, Inbred Strains; Time Factors; Transplantation, Homologous	1979
Cytotoxicity of misonidazole in vivo under conditions of prolonged contact of drug with the tumour cells. The British journal of radiology, 1979, Volume: 52, Issue:623 Topics: Animals; Cell Survival; Half-Life; Mice; Mice, Inbred BALB C; Misonidazole; Neoplasms, Experimental; Nephrectomy; Nitroimidazoles; Time Factors	1979
Hypoxic cell radiosensitizers--chemical aspects and in vitro models. Strahlentherapie. Sonderbande, 1978, Volume: 75 Topics: Animals; Cell Line; Chemical Phenomena; Chemistry; Cricetinae; Cricetulus; Hypoxia; Lung; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Structure-Activity Relationship	1978
Cytotoxic effects of the hypoxic cell radiosensitizer Ro 7-0582 to tumor cells in vivo. Radiation research, 1977, Volume: 72, Issue:3 Topics: Animals; Dose-Response Relationship, Radiation; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Time Factors	1977
The radiosensitizing effect of metronidazole and misonidazole (Ro-07-0582) on a human malignant melanoma grown in the athymic mutant nude mouse. The British journal of radiology, 1978, Volume: 51, Issue:605 Topics: Animals; Humans; Melanoma; Metronidazole; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation Dosage; Radiation-Sensitizing Agents; Time Factors	1978
Cytotoxicity and radiosensitization in mouse and man. The British journal of radiology, 1978, Volume: 51, Issue:608 Topics: Animals; Cell Survival; Humans; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Skin Neoplasms	1978
Effects of dimethyl sulfoxide and hypoxic cell radiosensitizers on the radiation response of the KHT murine tumor in vivo. Radiation research, 1977, Volume: 69, Issue:2 Topics: Animals; Cell Survival; Dimethyl Sulfoxide; Male; Metronidazole; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Protective Agents; Radiation-Sensitizing Agents; Sarcoma	1977
Radiosensitization of hypoxic tumor cells by simultaneous administration of hyperthermia and nitroimidazoles. Radiation research, 1977, Volume: 70, Issue:2 Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Survival; Deoxyuridine; Female; Hyperthermia, Induced; Hypoxia; Leukemia L1210; Metronidazole; Mice; Mice, Inbred Strains; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Sarcoma	1977
Radiosensitizing and cytocidal effects on hypoxic cells of RO-07-0582, and repair of x-ray injury, in an experimental mouse tumour. British journal of cancer, 1977, Volume: 35, Issue:4 Topics: Animals; Carcinoma, Squamous Cell; Hypoxia; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Skin Neoplasms; Transplantation, Homologous	1977
Hypoxic cell radiosensitizers and local control by X-ray of a transplanted tumour in mice. British journal of cancer, 1977, Volume: 35, Issue:6 Topics: Animals; Hypoxia; Metronidazole; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Nitrofurans; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy Dosage; Razoxane; Regeneration; Transplantation, Homologous	1977
Further investigations of the effects of the hypoxic-cell radiosensitizer, Ro-07-0582, on local control of a mouse tumour. British journal of cancer, 1977, Volume: 36, Issue:2 Topics: Animals; Female; Guinea Pigs; Neoplasm Metastasis; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1977
Radiosensitizers of hypoxic cells in solid tumors. Cancer treatment reviews, 1976, Volume: 3, Issue:4 Topics: Animals; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Fast Neutrons; Mammary Neoplasms, Experimental; Metronidazole; Mice; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Oxygen Consumption; Radiation-Sensitizing Agents; Radiotherapy Dosage	1976
Proceedings: Radiosensitization of hypoxic cells in solid tumours in mice. The British journal of radiology, 1975, Volume: 48, Issue:565 Topics: Animals; Fast Neutrons; Guinea Pigs; Humans; Hypoxia; Metronidazole; Mice; Nausea; Neoplasms, Experimental; Nitroimidazoles; Oxygen Consumption; Rabbits; Radiation-Sensitizing Agents; Rats	1975
Selective radiosensitization of the hypoxic cells of mouse tumors with the nitroimidazoles metronidazole and Ro 7-0582. Radiation research, 1975, Volume: 64, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Metronidazole; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; X-Ray Therapy	1975
Radioiodinated 1-(2-fluoro-4-iodo-2,4-dideoxy-beta-L-xylopyranosyl)-2-nitroimidazole: a novel probe for the noninvasive assessment of tumor hypoxia. Radiation research, 1992, Volume: 132, Issue:3 Topics: Animals; Cell Hypoxia; Dideoxynucleosides; Iodine Radioisotopes; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitroimidazoles; Radionuclide Imaging; Tissue Distribution	1992
[Radiosensitizing effect of a 2-nitroimidazole hydroxamate (KIN-804) to murine tumors]. Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1992, May-25, Volume: 52, Issue:5 Topics: Animals; Hydroxamic Acids; Lethal Dose 50; Male; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1992
Radiosensitization by 2-nitroimidazole nucleoside analog RP-170: radiosensitizing effects under both intravenous and oral administration. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Administration, Oral; Animals; Combined Modality Therapy; Etanidazole; Female; Injections, Intravenous; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents; Rats; Rats, Inbred Strains	1992
Modification of alkylating agent induced cell kill by 2-nitroimidazoles in unclamped and clamped SC 9L tumors. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Hypoxia; Cell Survival; Cyclophosphamide; Etanidazole; Ifosfamide; Male; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344	1992
Bioreductive drugs as post-irradiation sensitizers: comparison of dual function agents with SR 4233 and the mitomycin C analogue EO9. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:4 Topics: Animals; Antineoplastic Agents; Aziridines; Cell Hypoxia; Cell Survival; Combined Modality Therapy; Dose-Response Relationship, Drug; Indolequinones; Indoles; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Prodrugs; Tirapazamine; Triazines	1992
Tumor blood flow changes induced by chemical modifiers of radiation response. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Animals; Antineoplastic Agents; Blood Flow Velocity; Cisplatin; Doxorubicin; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1992
NLA-1: a 2-nitroimidazole radiosensitizer targeted to DNA by intercalation. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Aminoacridines; Animals; Cell Hypoxia; Cell Line; Combined Modality Therapy; DNA; DNA, Neoplasm; Intercalating Agents; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1992
Fluorine modification of nitroazole radiosensitizers for the enhancement of sensitizing activity with lowering toxicity: a pharmacokinetic characterization. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Animals; Brain; Combined Modality Therapy; Female; Lethal Dose 50; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Triazoles	1992
A comparison of radiosensitization by etanidazole and pimonidazole in mouse tumors. International journal of radiation oncology, biology, physics, 1991, Volume: 20, Issue:5 Topics: Animals; Cell Survival; Combined Modality Therapy; Etanidazole; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1991
A fluorinated 2-nitroimidazole, KU-2285, as a new hypoxic cell radiosensitizer. International journal of radiation oncology, biology, physics, 1991, Volume: 20, Issue:6 Topics: Animals; Combined Modality Therapy; Dose-Response Relationship, Radiation; Etanidazole; Female; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1991
Radioiodinated 1-(5-iodo-5-deoxy-beta-D-arabinofuranosyl)-2-nitroimidazole (iodoazomycin arabinoside: IAZA): a novel marker of tissue hypoxia. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1991, Volume: 32, Issue:9 Topics: Animals; Cell Hypoxia; Iodine Radioisotopes; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Tissue Distribution	1991
Dynamic measurements of hexafluoromisonidazole (CCI-103F) retention in mouse tumours by 1H/19F magnetic resonance spectroscopy. International journal of radiation biology, 1990, Volume: 58, Issue:6 Topics: Animals; Cell Hypoxia; Injections, Intraperitoneal; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles	1990
Flow cytometric evaluation of hypoxic cells in solid experimental tumours using fluorescence immunodetection. British journal of cancer, 1991, Volume: 63, Issue:1 Topics: Animals; Cell Hypoxia; Cricetinae; Cricetulus; Flow Cytometry; Fluorescent Antibody Technique; Neoplasms, Experimental; Nitroimidazoles; Sarcoma, Experimental; Theophylline	1991
Prediction of tumor radiosensitivity by hexafluoromisonidazole retention monitored by [1H]/[19F] magnetic resonance spectroscopy. Cancer communications, 1991, Volume: 3, Issue:5 Topics: Animals; Cell Hypoxia; Cell Survival; Gamma Rays; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Radiation Tolerance; Radiography; Radionuclide Imaging; Tumor Cells, Cultured	1991
Chemosensitization of the nitrosoureas by 2-nitroimidazoles in the subcutaneous 9L tumor model: pharmacokinetic and structure-activity considerations. International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:5 Topics: Animals; Carmustine; Drug Synergism; Etanidazole; Lomustine; Male; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Nitrosourea Compounds; Rats; Rats, Inbred F344; Structure-Activity Relationship	1990
Tumour radiosensitization by clofibrate and its analogs: possible mechanisms. Advances in experimental medicine and biology, 1990, Volume: 277 Topics: Animals; Bezafibrate; Clofibrate; Combined Modality Therapy; Etanidazole; Female; Hypoxia; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Regional Blood Flow	1990
Experimental intra-arterial administration of SR-2508 in the rabbit V2 carcinoma model. The British journal of radiology, 1989, Volume: 62, Issue:735 Topics: Animals; Etanidazole; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Neoplasms, Experimental; Nitroimidazoles; Rabbits; Radiation-Sensitizing Agents	1989
Ro 03-8799: preferential relative uptake in human tumor xenografts compared to a murine tumor: comparison with SR-2508. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Animals; Cell Line; Etanidazole; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Transplantation, Heterologous	1989
The effect of glutathione (GSH) depletion in vivo by buthionine sulfoximine (BSO) on the radiosensitization of SR 2508. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5 Topics: Animals; Buthionine Sulfoximine; Etanidazole; Glutathione; Methionine Sulfoximine; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy Dosage	1989
Radiosensitization by a new nucleoside analogue: 1-[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl-2-nitroimidazole (RP-170). International journal of radiation oncology, biology, physics, 1989, Volume: 17, Issue:3 Topics: Animals; Cell Survival; Combined Modality Therapy; Etanidazole; In Vitro Techniques; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents	1989
Characteristics of fluorinated nitroazoles as hypoxic cell radiosensitizers. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Animals; Cell Survival; Combined Modality Therapy; Hydrocarbons, Fluorinated; In Vitro Techniques; Lethal Dose 50; Mice; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Triazoles	1989
Demonstration of tumor-selective retention of fluorinated nitroimidazole probes by 19F magnetic resonance spectroscopy in vivo. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Animals; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Sarcoma, Experimental	1989
Stimulation by localized tumor hyperthermia of reductive bioactivation of 2-nitroimidazole benznidazole in mice. Cancer research, 1989, May-01, Volume: 49, Issue:9 Topics: Amines; Animals; Hyperthermia, Induced; Liver; Male; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Oxidation-Reduction	1989
Effects on intermediary metabolism in mouse tissues by Ro-03-8799. British journal of cancer, 1987, Volume: 56, Issue:3 Topics: Adenocarcinoma; Animals; Body Temperature; Brain; Glucose; Glucose-6-Phosphatase; Ketone Bodies; Lipid Metabolism; Liver; Liver Glycogen; Male; Mice; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1987
Influence of misonidazole, SR-2508, RSU-1069 and WR-2721 on spontaneous metastases in C57BL mice. International journal of radiation oncology, biology, physics, 1988, Volume: 14, Issue:2 Topics: Amifostine; Animals; Etanidazole; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasm Metastasis; Neoplasms, Experimental; Nitroimidazoles; Radiation-Protective Agents; Radiation-Sensitizing Agents	1988
Sensitization by SR-2508 plus Ro 03-8799. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Animals; Combined Modality Therapy; Drug Combinations; Etanidazole; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1986
SR-2508 plus buthionine sulfoximine or SR-2508 alone: effects on the radiation response and the glutathione content of a human tumor xenograft. Radiation research, 1987, Volume: 110, Issue:1 Topics: Buthionine Sulfoximine; Cell Survival; Cysteine; Etanidazole; Glutathione; Humans; Methionine Sulfoximine; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1987
Additivity of radiosensitization by the combination of SR 2508 (etanidazole) and Ro 03-8799 (pimonidazole) in a murine tumor system. International journal of radiation oncology, biology, physics, 1988, Volume: 15, Issue:3 Topics: Animals; Cell Survival; Drug Therapy, Combination; Etanidazole; Female; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1988
[Development of new hypoxic cell radiosensitizer in Japan]. Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:13 Topics: Animals; Dogs; Drug Evaluation, Preclinical; Etanidazole; Hydroxamic Acids; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1988
Nitroimidazole bioreductive metabolism. Quantitation and characterisation of mouse tissue benznidazole nitroreductases in vivo and in vitro. Biochemical pharmacology, 1987, Mar-15, Volume: 36, Issue:6 Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Cytosol; Kidney; Kinetics; Liver; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Neoplasms, Experimental; Nitroimidazoles; Nitroreductases; Oxidoreductases	1987
[Enhancement of the effect of radiotherapy of Guerin's carcinoma by tinidazole]. Eksperimental'naia onkologiia, 1987, Volume: 9, Issue:2 Topics: Animals; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Rats; Tinidazole	1987
Radiosensitization in vitro and in vivo by 3-nitrotriazoles. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Animals; Combined Modality Therapy; Cricetinae; Female; In Vitro Techniques; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitro Compounds; Nitroimidazoles; Radiation-Sensitizing Agents; Triazoles	1986
Covalent binding of a fluorinated 2-nitroimidazole to EMT-6 tumors in Balb/C mice: detection by F-19 nuclear magnetic resonance at 2.35 T. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Animals; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Oxygen	1986
Radiosensitization, pharmacokinetics, and toxicity of a 2-nitroimidazole nucleoside (RA-263). Radiation research, 1986, Volume: 105, Issue:2 Topics: Animals; Cell Line; Cell Survival; Cricetinae; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mutagenicity Tests; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1986
[Radioprotective phenomena in murine tumors induced by radiosensitizers at high dose levels]. Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1986, May-25, Volume: 46, Issue:5 Topics: Animals; Combined Modality Therapy; Mice; Neoplasms, Experimental; Nitroimidazoles; Oxadiazoles; Radiation-Protective Agents; Radiation-Sensitizing Agents	1986
Sensitization of cancer chemotherapeutic agents by nitroheterocyclics. Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cell Survival; Drug Synergism; Heterocyclic Compounds; Hydroxamic Acids; Hypoxia; Lomustine; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1986
Iodoazomycin riboside (1-(5'-iodo-5'-deoxyribofuranosyl)-2-nitroimidazole), a hypoxic cell marker. I. Synthesis and in vitro characterization. Radiation research, 1986, Volume: 105, Issue:2 Topics: Animals; Cell Survival; In Vitro Techniques; Iodine Radioisotopes; Mice; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1986
Binding of misonidazole to hypoxic cells in monolayer and spheroid culture: evidence that a side-chain label is bound as efficiently as a ring label. British journal of cancer, 1985, Volume: 51, Issue:2 Topics: Animals; Carbon Radioisotopes; Cell Aggregation; Cells, Cultured; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Structure-Activity Relationship; Tritium	1985
Regional measurements of [14C]misonidazole distribution and blood flow in subcutaneous RT-9 experimental tumors. Cancer research, 1985, Volume: 45, Issue:4 Topics: Animals; Carbon Radioisotopes; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Rats; Regional Blood Flow; Tissue Distribution	1985
Comparison of binding of [3H]misonidazole and [14C]misonidazole in multicell spheroids. Radiation research, 1985, Volume: 101, Issue:3 Topics: Animals; Carbon Radioisotopes; In Vitro Techniques; Misonidazole; Models, Biological; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Tritium	1985
Further characterization of 4-bromomisonidazole as a potential detector of hypoxic cells. Radiation research, 1985, Volume: 102, Issue:1 Topics: Animals; Autoradiography; Carbon Radioisotopes; Misonidazole; Models, Biological; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
Changes in misonidazole binding with hypoxic fraction in mouse tumors. International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:7 Topics: Animals; Hematocrit; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation Tolerance	1985
Carcinogenicity of 5-nitrofurans, 5-nitroimidazoles, 4-nitrobenzenes, and related compounds. Journal of the National Cancer Institute, 1973, Volume: 51, Issue:2 Topics: Adenocarcinoma; Animals; Benzene Derivatives; Carcinogens; Chemical Phenomena; Chemistry; Diet; Female; Kidney Neoplasms; Leukemia, Experimental; Leukemia, Lymphoid; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Nitrobenzenes; Nitrofurans; Nitroimidazoles; Rats	1973