Page last updated: 2024-08-21

azomycin and Chronic Illness

azomycin has been researched along with Chronic Illness in 123 studies

Research

Studies (123)

TimeframeStudies, this research(%)All Research%
pre-19905 (4.07)18.7374
1990's11 (8.94)18.2507
2000's21 (17.07)29.6817
2010's65 (52.85)24.3611
2020's21 (17.07)2.80

Authors

AuthorsStudies
Alvedro, A; Bhattacharyya, T; Cardinal, MV; Enriquez, GF; Freilij, H; Gilleman, Q; Gürtler, RE; Macchiaverna, NP; Martinez de Salazar, P; Mertens, P; Miles, MA; Molina, I; Murphy, N1
Barbosa, C; Carrillo, I; Castillo, C; Díaz-Araya, G; Fuentes-Retamal, S; González-Herrera, F; Guzmán-Rivera, D; Kemmerling, U; Machado, FS; Maya, JD; Quintero, H; Rabelo, RAN; Rates, M1
Sperandio da Silva, GM1
Albareda, MC; Alvarez, MG; Bertocchi, G; Castro Eiro, MD; Cesar, G; De Rissio, AM; Fernandez, M; Laucella, SA; Lococo, B; Natale, MA; Tarleton, RL; Viotti, R; White, BE; Zabaleta, F1
Carrilero, B; Franco, F; García-Vázquez, E; Gil-Gallardo, LJ; Iborra, MA; Segovia, M; Simón, M; Vázquez, C1
Alba Soto, CD; Areco, Y; Bellera, CL; Buchholz, B; Carrillo, C; Gelpi, RJ; Kelly, J; Miranda, C; Quarroz Braghini, J; Sbaraglini, ML; Talevi, A1
Egui, A; López, MC; Pérez-Antón, E; Segovia, M; Simón, M; Thomas, MC1
Arsuaga, M; Crespillo-Andújar, C; Díaz-Menéndez, M; López-Vélez, R; Monge-Maillo, B; Norman, F; Pérez-Molina, JA; Trigo, E1
Chappuis, F; Jackson, Y; Wyssa, B1
Carneiro, CM; Carvalho, LM; Correa-Oliveira, R; de Carvalho, TV; Fonseca, KDS; Madeira, JV; Medeiros, LDF; Molina, I; Perin, L; Vieira, PMA1
Goterris, L; Molina, I; Moure, Z; Oliveira, I; Pou, D; Pumarola, T; Salvador, F; Sánchez-Montalvá, A; Sao-Aviles, A; Serre-Delcor, N; Silgado, A; Sulleiro, E; Tavares de Oliveira, M; Treviño, B1
Carrilero, B; Gil-Gallardo, LJ; Iborra, MA; Romay-Barja, M; Segovia, M; Simón, M; Vázquez, C1
Alonso-Padilla, J; Cortes-Serra, N; Fernandez-Becerra, C; Gascon, J; Losada-Galvan, I; Pinazo, MJ1
Bangher, M; Bosch-Nicolau, P; Correa-Oliveira, R; de Paula, AMB; Eloi, S; Fernández, ML; Molina, I; Molina-Morant, D; Ribeiro, ALP; Salvador, F; Sanchez-Montalva, A; Sosa-Estani, S; Sulleiro, E; Villar, JC1
Bermúdez, JM; Cid, AG; Davies, C; Micheloud, JF; Negrette, OS; Parada, LA; Ragone, PG; Simonazzi, A1
Couto, NRB; Frade, VP; Oliveira, CDL; Sanches, C; Simões, NS1
Corral, RS; Hernández, M; Pérez Caballero, E; Santamaría, MH; Wicz, S1
Gonzalez Garay, AG; Martinez Garcia, M; Reyes, PP; Vallejo, M1
C B Q Figueiredo, R; Carrazone, C; Esmeraldo, AAM; G A M Cavalcanti, M; Gomes, YM; Higino, TMM; Júnior, WO; Lorena, VMB; Martins, SM; Moreira, LR; Nascimento, AV; Neves, PAF; Soares, AKA1
Britto, C; Castaño Barrios, L; Cruz Moreira, O; Lannes-Vieira, J; Martins Batista, A; Mata Dos Santos, HA; Resende Pereira, I; Silva, AAD; Vilar-Pereira, G1
Arias, E; Bizai, ML; Bottasso, O; Fabbro, D; Marcipar, I; Olivera, V; Suasnabar, S1
Fortaleza, CMCB; Nunes da Costa, EAP; Victória, C1
Carneiro, CM; Corrêa-Oliveira, R; Fonseca Murta, SM; Molina, I; Sales Junior, PA; Salvador, F; Sánchez-Montalvá, A1
Calbacho Robles, M; Crespillo-Andújar, C; Norman, FF; Pérez-Molina, JA1
Cuéllar, A; Egui, A; González, JM; López, MC; Pérez-Antón, E; Puerta, CJ; Segovia, M; Thomas, MC1
Chamorro-Tojeiro, S; Crespillo-Andújar, C; López-Vélez, R; Monge-Maillo, B; Norman, F; Pérez-Molina, JA1
Crespillo-Andújar, C; López-Polín, A; López-Vélez, R; Monge-Maillo, B; Norman, F; Pérez-Molina, JA; Venanzi-Rullo, E1
Bahia, MT; Caldas, IS; Caldas, S; Diniz, LF; Menezes, APJ; Nascimento, ÁFDSD; Novaes, RD1
Egui, A; Lasso, P; López, MC; Pérez-Antón, E; Thomas, MC1
Bierrenbach, AL; Busch, MP; Cardoso, CS; Colosimo, EA; Ferreira, AM; Ferreira, JE; Lee, TH; Oliveira, CDL; Oliveira, LC; Reingold, AL; Ribeiro, ALP; Sabino, EC; Silva, JLP1
Borchardt, RA; Tzizik, DM1
Alves-Silva, LS; Amarante, E; Barral-Netto, M; Barreto, LO; Camara, EJN; Carvalho, JS; Chiacchio, G; Cunha, M; Gatto, R; Guimarães, BAC; Lessa, RA; Mendonca, VRR; Souza, LCL1
Clares, MP; Delgado-Pinar, E; García-España, E; Marín, C; Martín-Escolano, J; Martín-Escolano, R; Martin-Montes, Á; Medina-Carmona, E; Molina-Carreño, D; Pitarch-Jarque, J; Rosales, MJ; Sánchez-Moreno, M1
Alonso-Padilla, J; Cortes-Serra, N; Gascon, J; Pinazo, MJ; Reverter, JC; Tassies, D1
Albareda, MC; Alvarez, MG; Castro Eiro, MD; Cesar, GL; Laucella, SA; Natale, MA1
Asti, L; Bartsch, SM; Bottazzi, ME; Falcón-Lezama, JA; Hotez, PJ; Lee, BY; Meymandi, S; Randall, S; Strych, U1
Muñoz-Calderon, A; Schijman, AG; Sulleiro, E1
Arias, E; Bizai, ML; Denner, S; Fabbro, D; Olivera, V; Pravia, C; Ruiz, AM; Velazquez, E1
Basombrío, MA; Cimino, RO; D'Amato, AM; Diosque, P; Gil, JF; Lacunza, CD; Lauthier, JJ; Nasser, JR; Orellana, V; Pérez Brandán, C; Ragone, PG; Rumi, MM; Tomasini, N1
Alarcón de Noya, B; Araujo-Jorge, T; Gascon, J; Grijalva, MJ; Guhl, F; López, MC; Ramsey, JM; Ribeiro, I; Schijman, AG; Sosa-Estani, S; Torrico, F; Viotti, R1
Blanco-Grau, A; Cabezos, J; Gómez i Prat, J; Molina, I; Pahissa, A; Pou, D; Roure, S; Salvador, F; Sánchez-Montalvá, A; Serre, N; Sulleiro, E; Treviño, B; Valerio, L; Vidal, X1
Imai, K; Kawana, A; Kurane, I; Maeda, T; Mikita, K; Miura, S; Miyahira, Y; Osa, M; Sayama, Y1
Blaser, A; Denny, WA; Franzblau, SG; Kmentova, I; Ma, Z; Palmer, BD; Sutherland, HS; Thompson, AM; Wan, B; Wang, Y3
Beppu, T; Kobayashi, M; Ogasawara, K; Ogawa, A; Saura, H; Takai, Y; Terasaki, K; Yoshida, K1
Almeida, IC; Bustamante, J; Gascon, J; Lopez, MC; Pinazo, MJ; Thomas, MC1
Albareda, MC; Laucella, SA1
Chatelain, E; Francisco, AF; Jayawardhana, S; Kelly, JM; Lewis, MD; Taylor, MC1
Almirante, B; Molina, I; Salvador, F; Sánchez-Montalvá, A; Sao Avilés, A; Serre, N; Treviño, B1
Avezum, A; Bonilla, L; Bonilla, R; Britto, C; Connolly, SJ; Guhl, F; Lazdins, J; Marin-Neto, JA; Mattos, A; Meeks, B; Morillo, CA; Pogue, J; Quiroz, R; Rao-Melacini, P; Rassi, A; Rosas, F; Sosa-Estani, S; Velazquez, E; Villena, E; Yusuf, S1
Ciapponi, A; Comandé, D; Cuesta, CB; Hicks, E; Roberts, KN; Sguassero, Y; Sosa-Estani, S1
Abril, M; Albizu, CL; Álvarez, MG; Bertocchi, G; Cura, C; Fernández, M; Hernández, Y; Lococo, B; Ramírez, JC; Schijman, A; Sosa-Estani, S; Viotti, R1
Bruhn, DF; Lee, RE; Lenaerts, AJ; Liu, J; Scherman, MS; Singh, AP; Yang, L1
Komajda, M; Ruschitzka, F1
Abras, A; Aldasoro, E; de Almeida, IC; de Lazzari, E; Gallego, M; Gascon, J; Izquierdo, L; Marques, AF; Muñoz, J; Pinazo, MJ; Posada, Ede J; Reverter, JC; Tassies, D; Tebar, S1
Bierrenbach, AL; Cardoso, CS; Cunha-Neto, E; de Oliveira, LC; Ferreira, AM; Ferreira, JE; Haikal, DS; Oliveira, CD; Reingold, AL; Ribeiro, AL; Sabino, EC1
Ayala, V; Bisio, M; Burgos, JM; Contreras, A; Coppede, M; Elean, JC; García-Bournissen, F; Gómez, KA; Grippo, V; Herrera, V; Juiz, NA; Lafón, SO; Levin, MJ; Levitus, G; Longhi, SA; López, C; Mujica, HD; Niborski, LL; Ramirez, JC; Schijman, AG1
Branquinho, RT; de Mello, CG; Lana, Md; Milagre, MM; Mosqueira, VC; Oliveira, MT; Saúde-Guimarães, DA1
Pays, JF1
Gutiérrez, C; López-Vélez, R; Monge-Maillo, B; Norman, FF; Pérez-Molina, JA; Vallejo, A1
Cardoso, CS; de Oliveira, LC; Ferreira, AM; Haikal, DS; Oliveira, CD; Ribeiro, AL; Sabino, EC1
Castillo, C; Cramer, A; González-Herrera, F; Kemmerling, U; Liempi, A; Machado, FS; Maya, JD; Pimentel, P1
Marin, JA; Rassi, A1
Apt, W; Beloscar, J; Bonilla, LR; Colombo, H; Cuneo, C; Del Carmen Bangher, M; Echeverria, LE; Gao, P; Gascon, J; Mallagray, M; McCarthy, M; Meeks, B; Milesi, R; Molina, I; Morillo, CA; Perez-Molina, JA; Sosa-Estani, S; Waskin, H; Wei, B; Wyss, F; Yusuf, S1
Bahia, MT; de Lana, M; dos Santos, DM; Guedes, PM; Machado-Coelho, GL; Talvani, A1
Alvarez, MG; Armenti, A; Bertocchi, G; Lococo, B; Petti, M; Vigliano, C; Viotti, R1
Balbinot, MM; Fernandes, CD; Liarte, DB; Romanha, A; Scholl, D; Steindel, M; Tiecher, FM1
Budni, P; Colepicolo, P; Dalmarco, EM; Farias, MS; Filho, DW; Fröde, TS; Oliveira-Silva, D; Parisotto, EB; Pedrosa, RC; Ribeiro, CM1
Avezum, A; Marin-Neto, JA; Mattos, AC; Morillo, CA; Rassi, A; Sosa-Estani, S; Yusuf, S1
Bassets, G; Escribà, JM; Lima, MA; Marchiol, A; Palma, PP; Ponce, C; Ponce, E; Romero, Ade D; Viñas, PA; Zúniga, C1
Albajar-Viñas, P; Bahia, MT; Coura, JR; Dias, JC; Lana, Md; Lopes, LA; Machado-de-Assis, GF; Martins, HR; Martins-Filho, OA; Montoya, RA; Wendling, AP1
Condon, D; Dhiman, M; Garg, NJ; Guan, Z; Gupta, S; Lui, C; Wen, JJ1
Correia, D; Fuzissaki, J; Lages-Silva, E; Molina, RJ; Niederhaur, S; Oliveira, LF; Prata, A; Silva, VJ1
Clayton, J2
Apt, W1
Ferreira, J; Kemmerling, U; López-Muñoz, R; Maya, JD; Morello, A; Orellana, M1
Arias, E; Bizai, ML; Bottasso, O; del Barco, M; Denner, S; Diez, C; Fabbro, DL; Mancipar, I; Marcipar, I; Mendicino, D; Olivera, V; Streiger, M1
Bern, C1
Le Loup, G; Lescure, FX; Pialoux, G1
Ayala, E; Fisa, R; Gállego, M; Gascon, J; Monteagudo, J; Muñoz, J; Pinazo, MJ; Posada, Ede J; Reverter, JC; Tàssies, D1
Alvarez, MG; Armenti, A; Bertocchi, G; Cooley, G; De Rissio, AM; Laucella, S; Lococo, B; Petti, M; Tarleton, R; Vigliano, C; Viotti, R1
Aguiar, C; Almeida, EA; Batista, AM; Costa, SC; Guariento, ME; Pavan, TB; Wanderley, JS1
Chambela, MC; de Sousa, AS; do Brasil, PE; Hasslocher-Moreno, AM; Sperandio da Silva, GM; Xavier, SS1
Bahia, MT; Gravel, AS; Lima, WG; Martins, TA; Santos, FM; Talvani, A; Torres, RM1
Albareda, MC; Alvarez, MG; Argüello, RJ; Armenti, AH; Bertocchi, G; Laucella, SA; Meckert, PC; Tarleton, RL; Vigliano, C1
Marcondes de Rezende, J; Rassi, A1
Alvarez, MG; Bertocchi, G; Lococo, B; Petti, M; Vigliano, C; Viotti, R1
Albareda, MC; Alvarez, MG; Armenti, AH; Bertocchi, G; Cooley, G; Laucella, SA; Lococo, BE; Perez-Mazliah, DE; Petti, M; Tarleton, RL; Viotti, R1
Azevedo, MA; Bahia, MT; Caldas, IS; da Matta Guedes, PM; da Silva do Nascimento, AF; de Figueiredo Diniz, L; de Lima, WG; dos Santos, FM; Martins, TA; Neto, RM; Talvani, A; Torres, RM1
Gascon, J; Guerrero, L; Pinazo, MJ; Posada, E; Rodríguez, E; Soy, D1
Basile, DP; Donohoe, DL; Mattson, DL; Roethe, K1
Campos-de-Carvalho, AC; Garcia, S; Ramos, CO; Ribeiro-Dos-Santos, R; Rodrigues, MM; Senra, JF; Soares, MB; Vilas-Boas, F1
Angus, PW; Burrell, LM; Cooper, ME; Lew, RA; Paizis, G; Schembri, JM; Shaw, T; Smith, AI; Tikellis, C; Warner, FJ; Zuilli, A1
Reyes, PA; Vallejo, M1
Alvarez, MG; Armenti, A; Bertocchi, G; Lococo, B; Petti, M; Postan, M; Vigliano, C; Viotti, R1
Braz, LM; Gakiya, E; Ibrahim, KY; Lopes, MH; Nunes Westphalen, EV; Oliveira, OC; Sartori, AM; Shikanai-Yasuda, MA1
Bustamante, JM; Enders, JE; Fernández, AR; Fretes, RE; Paglini-Oliva, P; Presti, MS; Rivarola, HW1
El Masri, M; Karcz, DA; Lennox, HA; Tales, H1
Bahia, MT; Caldas, IS; Caldas, S; Carneiro, CM; da Matta Guedes, PM; de Lana, M; Talvani, A1
Manigot, DA1
Jennings, FW; Miller, BM; Murray, PK; Urquhart, GM1
Jennings, FW; Urquhart, GM1
Almiron, M; Campetella, O; Frasch, AC; Ganzález Cappa, SM; Guillen, I; Leguizamón, MS; Russomando, G1
Cancado, JR; Galvao, LM; Gazzinelli, RT; Krautz, G; Krettli, AU; Lima, PC; Scharfstein, J1
Bestetti, RB1
Bayo, R; Ceraso, D; De Rissio, A; Dengra, C; Dictar, M; Koziner, B; Luna, C; Riarte, A; Segura, E; Sinagra, A; Verón, MT1
Bellotti, G; Bocchi, EA; Fiorelli, A; Higuchi, ML; Jatene, A; Pileggi, F; Stolf, N; Uip, D; Vieira, ML1
Rassi Júnior, A; Rassi, A1
Måseide, K; Rofstad, EK1
Brener, Z; Loebenberg, D; Martins-Filho, O; Molina, J; Romanha, AJ; Urbina, JA1
Britto, C; Cardoso, A; Fernandes, O; Macedo, V; Silveira, C1
Bonté, F; Ferreira, ME; Fournet, A; Lavault, M; Nakayama, H; Rojas de Arias, A; Samudio, M; Schinini, A; Torres de Ortiz, S; Vera de Bilbao, N1
Giovannoni, AG; Montero, A1
Ferreira, ME; Fournet, A; Nakayama, H; Rojas de Arias, A; Schinini, A; Torres, S; Vera de Bilbao, N1
Apt, W; Doren, G; Gabor, M; Perez, C1
da Silva, JS; Souza, SC; Takahashi, CS1
Frasch, AC; Jazín, EE; Luquetti, AO; Rassi, A1
Gallerano, RH; Marr, JJ; Sosa, RR1
Gallerano, RH; Meirovich, CI; Montrull, HL; Sosa, RR1

Reviews

18 review(s) available for azomycin and Chronic Illness

ArticleYear
Ideal benznidazole dose regimen in chronic chagasic patients: a systematic review.
    Revista do Instituto de Medicina Tropical de Sao Paulo, 2020, Volume: 62

    Topics: Adult; Chagas Disease; Chronic Disease; Humans; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2020
Trypanocidal drugs for late-stage, symptomatic Chagas disease (Trypanosoma cruzi infection).
    The Cochrane database of systematic reviews, 2020, 12-11, Volume: 12

    Topics: Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Humans; Nifurtimox; Nitroimidazoles; Parasitemia; Placebos; Randomized Controlled Trials as Topic; Trypanocidal Agents; Trypanosoma cruzi

2020
Experimental and Clinical Treatment of Chagas Disease: A Review.
    The American journal of tropical medicine and hygiene, 2017, Volume: 97, Issue:5

    Topics: Animals; Chagas Disease; Chronic Disease; Clinical Trials as Topic; Disease Models, Animal; Drug Compounding; Humans; Incidence; Latin America; Nanoparticles; Nifurtimox; Nitroimidazoles; Observational Studies as Topic; Randomized Controlled Trials as Topic; Tissue Distribution; Trypanocidal Agents; Trypanosoma cruzi

2017
Safety Profile of Benznidazole in the Treatment of Chronic Chagas Disease: Experience of a Referral Centre and Systematic Literature Review with Meta-Analysis.
    Drug safety, 2018, Volume: 41, Issue:11

    Topics: Age Factors; Chagas Disease; Chronic Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Nitroimidazoles; Prospective Studies; Sex Factors; Trypanocidal Agents

2018
Dynamics of T Cells Repertoire During Trypanosoma cruzi Infection and its Post-Treatment Modulation.
    Current medicinal chemistry, 2019, Volume: 26, Issue:36

    Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chagas Disease; Chronic Disease; Disease Progression; Humans; Infectious Disease Transmission, Vertical; Nitroimidazoles; Risk Factors; Trypanosoma cruzi

2019
Role of nucleic acid amplification assays in monitoring treatment response in chagas disease: Usefulness in clinical trials.
    Acta tropica, 2019, Volume: 199

    Topics: Biomarkers; Chagas Disease; Chronic Disease; Drug Resistance; Humans; Nifurtimox; Nitroimidazoles; Nucleic Acids; Parasite Load; Real-Time Polymerase Chain Reaction; Treatment Failure; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2019
Chronic Chagas disease with advanced cardiac complications in Japan: Case report and literature review.
    Parasitology international, 2015, Volume: 64, Issue:5

    Topics: Animals; Chagas Disease; Chronic Disease; Female; Heart Failure; Humans; Middle Aged; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2015
Biomarkers of therapeutic responses in chronic Chagas disease: state of the art and future perspectives.
    Memorias do Instituto Oswaldo Cruz, 2015, Volume: 110, Issue:3

    Topics: Biomarkers; Chagas Disease; Chronic Disease; Humans; Nitroimidazoles; Trypanocidal Agents

2015
Modulation of Trypanosoma cruzi-specific T-cell responses after chemotherapy for chronic Chagas disease.
    Memorias do Instituto Oswaldo Cruz, 2015, Volume: 110, Issue:3

    Topics: Antigens, Protozoan; Chagas Disease; Chronic Disease; Humans; Nitroimidazoles; T-Lymphocytes; Trypanocidal Agents; Trypanosoma cruzi

2015
Course of Chronic Trypanosoma cruzi Infection after Treatment Based on Parasitological and Serological Tests: A Systematic Review of Follow-Up Studies.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Adult; Antibodies, Protozoan; Chagas Disease; Child; Chronic Disease; Cohort Studies; Disease Progression; DNA, Protozoan; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique, Indirect; Follow-Up Studies; Hemagglutination Tests; Humans; Nifurtimox; Nitroimidazoles; Parasitemia; Randomized Controlled Trials as Topic; Treatment Failure; Trypanocidal Agents; Trypanosoma cruzi; Xenodiagnosis

2015
Side effects of benznidazole as treatment in chronic Chagas disease: fears and realities.
    Expert review of anti-infective therapy, 2009, Volume: 7, Issue:2

    Topics: Age Factors; Animals; Chagas Disease; Chronic Disease; Humans; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2009
Current and developing therapeutic agents in the treatment of Chagas disease.
    Drug design, development and therapy, 2010, Sep-24, Volume: 4

    Topics: Acute Disease; Animals; Chagas Disease; Chronic Disease; Humans; Nifurtimox; Nitroimidazoles; Time Factors; Treatment Outcome; Trypanocidal Agents

2010
Chagas disease: Present status of pathogenic mechanisms and chemotherapy.
    Biological research, 2010, Volume: 43, Issue:3

    Topics: Acute Disease; Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Humans; Mice; Nifurtimox; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2010
Antitrypanosomal therapy for chronic Chagas' disease.
    The New England journal of medicine, 2011, Jun-30, Volume: 364, Issue:26

    Topics: Adult; Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Disease Progression; Electrocardiography; Female; Humans; Life Cycle Stages; Nifurtimox; Nitroimidazoles; Practice Guidelines as Topic; Trypanocidal Agents; Trypanosoma cruzi

2011
Update in treatment of Chagas disease.
    Current opinion in infectious diseases, 2011, Volume: 24, Issue:5

    Topics: Chagas Disease; Chronic Disease; Humans; Immune Tolerance; Immunocompromised Host; Nitroimidazoles; Triazoles; Trypanocidal Agents; Trypanosoma cruzi

2011
American trypanosomiasis (Chagas disease).
    Infectious disease clinics of North America, 2012, Volume: 26, Issue:2

    Topics: Chagas Disease; Chronic Disease; Humans; Nifurtimox; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2012
Trypanocidal drugs for late stage, symptomatic Chagas disease (Trypanosoma cruzi infection).
    The Cochrane database of systematic reviews, 2005, Oct-19, Issue:4

    Topics: Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Clinical Trials as Topic; Humans; Imidazoles; Nifurtimox; Nitroimidazoles; Trypanocidal Agents

2005
Chagas disease: clinical overview and implications for nursing.
    Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses, 2007, Volume: 16, Issue:4

    Topics: Acute Disease; Animals; Canada; Chagas Disease; Chronic Disease; Emigration and Immigration; Hispanic or Latino; Humans; Immunologic Tests; Incidence; Insect Control; Insect Vectors; Nifurtimox; Nitroimidazoles; Nurse's Role; Prevalence; Primary Prevention; Risk Factors; South America; Travel; Triatoma; Trypanocidal Agents; United States

2007

Trials

9 trial(s) available for azomycin and Chronic Illness

ArticleYear
Efficacy and safety assessment of different dosage of benznidazol for the treatment of Chagas disease in chronic phase in adults (MULTIBENZ study): study protocol for a multicenter randomized Phase II non-inferiority clinical trial.
    Trials, 2020, Apr-15, Volume: 21, Issue:1

    Topics: Adult; Aftercare; Argentina; Brazil; Case-Control Studies; Chagas Disease; Chronic Disease; Colombia; Double-Blind Method; Female; Humans; Male; Neglected Diseases; Nitroimidazoles; Parasite Load; Safety; Spain; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2020
Randomized trial of posaconazole and benznidazole for chronic Chagas' disease.
    The New England journal of medicine, 2014, May-15, Volume: 370, Issue:20

    Topics: Adult; Chagas Disease; Chronic Disease; DNA, Protozoan; Female; Humans; Intention to Treat Analysis; Male; Middle Aged; Nitroimidazoles; Prospective Studies; Transaminases; Treatment Outcome; Triazoles; Trypanocidal Agents; Trypanosoma cruzi

2014
Randomized Trial of Benznidazole for Chronic Chagas' Cardiomyopathy.
    The New England journal of medicine, 2015, Volume: 373, Issue:14

    Topics: Adult; Aged; Cardiovascular Diseases; Chagas Cardiomyopathy; Chronic Disease; Disease Progression; Female; Genotype; Humans; Male; Middle Aged; Nitroimidazoles; Parasite Load; Polymerase Chain Reaction; Proportional Hazards Models; Prospective Studies; Treatment Failure; Trypanocidal Agents; Trypanosoma cruzi

2015
Changes in the immune response after treatment with benznidazole versus no treatment in patients with chronic indeterminate Chagas disease.
    Acta tropica, 2016, Volume: 164

    Topics: Adult; Aged; Biomarkers; Chagas Disease; Chronic Disease; Female; Humans; Male; Middle Aged; Nitroimidazoles; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2016
Benznidazole and Posaconazole in Eliminating Parasites in Asymptomatic T. Cruzi Carriers: The STOP-CHAGAS Trial.
    Journal of the American College of Cardiology, 2017, Feb-28, Volume: 69, Issue:8

    Topics: Administration, Oral; Adult; Chagas Disease; Chronic Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nitroimidazoles; Prospective Studies; Single-Blind Method; Triazoles; Trypanocidal Agents; Trypanosoma cruzi

2017
Sequential combined treatment with allopurinol and benznidazole in the chronic phase of Trypanosoma cruzi infection: a pilot study.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:2

    Topics: Adult; Allopurinol; Antiprotozoal Agents; B-Lymphocytes; Chagas Disease; Chronic Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Pilot Projects; T-Lymphocytes; Treatment Outcome; Trypanosoma cruzi

2013
Long-term cardiac outcomes of treating chronic Chagas disease with benznidazole versus no treatment: a nonrandomized trial.
    Annals of internal medicine, 2006, May-16, Volume: 144, Issue:10

    Topics: Adult; Animals; Antibodies, Protozoan; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Disease Progression; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Prognosis; Sensitivity and Specificity; Trypanocidal Agents; Trypanosoma cruzi

2006
Therapeutic efficacy of allopurinol in patients with chronic Chagas' disease.
    The American journal of tropical medicine and hygiene, 1990, Volume: 43, Issue:2

    Topics: Adult; Allopurinol; Chagas Disease; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Nifurtimox; Nitroimidazoles; Trypanocidal Agents

1990
[Allopurinol in the treatment of chronic Chagas' disease].
    Arquivos brasileiros de cardiologia, 1985, Volume: 45, Issue:3

    Topics: Allopurinol; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Nifurtimox; Nitroimidazoles; Trypanocidal Agents

1985

Other Studies

96 other study(ies) available for azomycin and Chronic Illness

ArticleYear
Assessing antibody decline after chemotherapy of early chronic Chagas disease patients.
    Parasites & vectors, 2021, Oct-20, Volume: 14, Issue:1

    Topics: Adolescent; Antibodies, Protozoan; Chagas Disease; Chronic Disease; Cohort Studies; Female; Humans; Immunoglobulin G; Immunologic Tests; Male; Molecular Diagnostic Techniques; Nifurtimox; Nitroimidazoles; Pilot Projects; Time Factors; Trypanocidal Agents; Trypanosoma cruzi

2021
Aspirin-triggered resolvin D1 reduces parasitic cardiac load by decreasing inflammation in a murine model of early chronic Chagas disease.
    PLoS neglected tropical diseases, 2021, Volume: 15, Issue:11

    Topics: Animals; Chagas Cardiomyopathy; Chronic Disease; Disease Models, Animal; Docosahexaenoic Acids; Female; Heart; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nitroimidazoles; Parasite Load; Receptors, Formyl Peptide; Trypanosoma cruzi

2021
Traditional use of benznidazole with weekly clinical follow-up indicate to be an important approach for the etiologic treatment of Chagas disease.
    Memorias do Instituto Oswaldo Cruz, 2022, Volume: 117

    Topics: Chagas Disease; Chronic Disease; Follow-Up Studies; Humans; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2022
B-Cell Responses in Chronic Chagas Disease: Waning of Trypanosoma cruzi-Specific Antibody-Secreting Cells Following Successful Etiological Treatment.
    The Journal of infectious diseases, 2023, 05-29, Volume: 227, Issue:11

    Topics: B-Lymphocytes; Chagas Disease; Chronic Disease; Humans; Nifurtimox; Nitroimidazoles; Persistent Infection; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2023
Tolerance and Adherence of Patients with Chronic Chagas Disease Treated with Benznidazole.
    Revista da Sociedade Brasileira de Medicina Tropical, 2023, Volume: 56

    Topics: Chagas Disease; Chronic Disease; Drug-Related Side Effects and Adverse Reactions; Humans; Nitroimidazoles; Prospective Studies; Retrospective Studies; Trypanocidal Agents; Trypanosoma cruzi

2023
Combined therapy with Benznidazole and repurposed drugs Clofazimine and Benidipine for chronic Chagas disease.
    European journal of medicinal chemistry, 2019, 12-15, Volume: 184

    Topics: Animals; Chagas Disease; Chlorocebus aethiops; Chronic Disease; Clofazimine; Combined Modality Therapy; Dihydropyridines; Female; Humans; Mice; Mice, Inbred C3H; Nitroimidazoles; Trypanocidal Agents; Vero Cells

2019
Immunological exhaustion and functional profile of CD8
    Acta tropica, 2020, Volume: 202

    Topics: Biomarkers; CD8-Positive T-Lymphocytes; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Costimulatory and Inhibitory T-Cell Receptors; Cytokines; Humans; Nitroimidazoles; Programmed Cell Death 1 Receptor; Signaling Lymphocytic Activation Molecule Family; Trypanocidal Agents; Trypanosoma cruzi

2020
Comparison of the toxicity of two treatment schemes with benznidazole for chronic Chagas disease: a prospective cohort study in two Spanish referral centres.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2020, Volume: 26, Issue:3

    Topics: Adult; Chagas Disease; Chronic Disease; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Nitroimidazoles; Prospective Studies; Referral and Consultation; Spain; Trypanocidal Agents; Trypanosoma cruzi

2020
Tolerance to nifurtimox and benznidazole in adult patients with chronic Chagas' disease.
    The Journal of antimicrobial chemotherapy, 2020, 03-01, Volume: 75, Issue:3

    Topics: Adult; Chagas Disease; Chronic Disease; Drug Tolerance; Humans; Nifurtimox; Nitroimidazoles; Switzerland; Trypanocidal Agents; Trypanosoma cruzi

2020
Low-dose of benznidazole promotes therapeutic cure in experimental chronic Chagas' disease with absence of parasitism in blood, heart and colon.
    Experimental parasitology, 2020, Volume: 210

    Topics: Acute Disease; Animals; Blood; Chagas Disease; Chronic Disease; Colon; Cyclophosphamide; Female; Heart; Immunosuppression Therapy; Mice; Neglected Diseases; Nitroimidazoles; Real-Time Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma cruzi

2020
Usefulness of real-time PCR during follow-up of patients treated with Benznidazole for chronic Chagas disease: Experience in two referral centers in Barcelona.
    PLoS neglected tropical diseases, 2020, Volume: 14, Issue:2

    Topics: Chagas Disease; Chronic Disease; Humans; Nitroimidazoles; Real-Time Polymerase Chain Reaction; Retrospective Studies; Spain; Trypanocidal Agents

2020
The Clinical and Parasitologic Follow-up of Trypanosoma cruzi-infected Children in a Nonendemic Country.
    The Pediatric infectious disease journal, 2020, Volume: 39, Issue:6

    Topics: Adolescent; Chagas Disease; Child; Child, Preschool; Chronic Disease; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Nitroimidazoles; Prospective Studies; Spain; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2020
State-of-the-art in host-derived biomarkers of Chagas disease prognosis and early evaluation of anti-Trypanosoma cruzi treatment response.
    Biochimica et biophysica acta. Molecular basis of disease, 2020, 07-01, Volume: 1866, Issue:7

    Topics: Biomarkers; Chagas Disease; Chronic Disease; Gastrointestinal Tract; Heart; Host-Parasite Interactions; Humans; Nifurtimox; Nitroimidazoles; Prognosis; Treatment Outcome; Trypanosoma cruzi

2020
Benznidazole/Poloxamer 407 Solid Dispersion as a New Strategy to Improve the Treatment of Experimental Trypanosoma cruzi Infection.
    The Journal of parasitology, 2020, 06-01, Volume: 106, Issue:3

    Topics: Acute Disease; Animals; Antibodies, Protozoan; Aspartate Aminotransferases; Chagas Disease; Chronic Disease; Disease Models, Animal; Excipients; Female; Heart; Mice; Myocardium; Nitroimidazoles; Parasitemia; Poloxamer; Quadriceps Muscle; Random Allocation; Real-Time Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma cruzi

2020
Dual chemotherapy with benznidazole at suboptimal dose plus curcumin nanoparticles mitigates Trypanosoma cruzi-elicited chronic cardiomyopathy.
    Parasitology international, 2021, Volume: 81

    Topics: Animals; Chagas Cardiomyopathy; Chronic Disease; Curcumin; Female; Male; Mice; Mice, Inbred C57BL; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2021
Benznidazole: Hero or villain of cellular immune response in chronic Chagas disease patients?
    Immunobiology, 2021, Volume: 226, Issue:1

    Topics: Antigen Presentation; B7-1 Antigen; Cells, Cultured; Chagas Disease; Chronic Disease; HLA-DR Antigens; Humans; Immunity, Cellular; Leukocytes, Mononuclear; Lymphocyte Activation; Macrophage Activation; Nitroimidazoles; Phagocytosis; Trypanocidal Agents; Trypanosoma cruzi

2021
Memory impairment in chronic experimental Chagas disease: Benznidazole therapy reversed cognitive deficit in association with reduction of parasite load and oxidative stress in the nervous tissue.
    PloS one, 2021, Volume: 16, Issue:1

    Topics: Animals; Chagas Disease; Chronic Disease; Cognition; Cognitive Dysfunction; Female; Mice, Inbred C57BL; Nitroimidazoles; Oxidative Stress; Parasite Load; Trypanocidal Agents; Trypanosoma cruzi

2021
Levels of anti-B13 antibodies over time in a cohort of chronic infected by Trypanosoma cruzi. Its relationship with specific treatment and clinical status.
    Acta tropica, 2021, Volume: 218

    Topics: Adult; Animals; Antibodies, Protozoan; Antigens, Protozoan; Argentina; Chagas Disease; Chronic Disease; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Male; Nifurtimox; Nitroimidazoles; Retrospective Studies; Trypanocidal Agents; Trypanosoma cruzi; Young Adult

2021
Predictors of development of cardiac and digestive disorders among patients with indeterminate chronic Chagas Disease.
    PLoS neglected tropical diseases, 2021, Volume: 15, Issue:8

    Topics: Adult; Antiprotozoal Agents; Brazil; Chagas Disease; Chronic Disease; Digestive System Diseases; Female; Heart Diseases; Humans; Male; Middle Aged; Nitroimidazoles; Retrospective Studies; Trypanosoma cruzi

2021
Severe immune thrombocytopaenia in a patient taking benznidazole for chronic Chagas disease.
    BMJ case reports, 2018, Mar-27, Volume: 2018

    Topics: Adult; Chagas Disease; Chronic Disease; Female; Humans; Immunosuppressive Agents; Nitroimidazoles; Thrombocytopenia

2018
Impact of benznidazole treatment on the functional response of Trypanosoma cruzi antigen-specific CD4+CD8+ T cells in chronic Chagas disease patients.
    PLoS neglected tropical diseases, 2018, Volume: 12, Issue:5

    Topics: Adult; Antibodies, Protozoan; Antiprotozoal Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chagas Disease; Chronic Disease; Cytokines; Female; Humans; Interleukin-2; Leukocytes, Mononuclear; Male; Nitroimidazoles; Trypanosoma cruzi; Tumor Necrosis Factor-alpha

2018
Toxicity of nifurtimox as second-line treatment after benznidazole intolerance in patients with chronic Chagas disease: when available options fail.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2018, Volume: 24, Issue:12

    Topics: Adult; Chagas Disease; Chronic Disease; Cohort Studies; Drug Tolerance; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Nifurtimox; Nitroimidazoles; Prospective Studies; Retreatment; Trypanosoma cruzi

2018
Parasitaemia and parasitic load are limited targets of the aetiological treatment to control the progression of cardiac fibrosis and chronic cardiomyopathy in Trypanosoma cruzi-infected dogs.
    Acta tropica, 2019, Volume: 189

    Topics: Acute Disease; Animals; Chagas Cardiomyopathy; Chronic Disease; Collagen Type III; Disease Models, Animal; Disease Progression; DNA, Protozoan; Dogs; Drug Resistance; Fibrosis; Heart; Myocardium; Nitroimidazoles; Parasite Load; Parasitemia; Trypanocidal Agents; Trypanosoma cruzi

2019
Beneficial effects of benznidazole in Chagas disease: NIH SaMi-Trop cohort study.
    PLoS neglected tropical diseases, 2018, Volume: 12, Issue:11

    Topics: Aftercare; Brazil; Chagas Disease; Chronic Disease; Follow-Up Studies; Humans; National Institutes of Health (U.S.); Nitroimidazoles; Parasitemia; Prospective Studies; Trypanocidal Agents; Trypanosoma cruzi; United States

2018
Chagas disease: An underrecognized diagnosis.
    JAAPA : official journal of the American Academy of Physician Assistants, 2018, Volume: 31, Issue:12

    Topics: Acute-Phase Reaction; Cardiomyopathies; Chagas Disease; Chronic Disease; Diagnosis, Differential; Female; Humans; Male; Megacolon; Nifurtimox; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi; United States

2018
Elevated IL-17 levels and echocardiographic signs of preserved myocardial function in benznidazole-treated individuals with chronic Chagas' disease.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2019, Volume: 79

    Topics: Chagas Disease; Chronic Disease; Cross-Sectional Studies; Cytokines; Echocardiography; Female; Heart; Humans; Interleukin-17; Male; Middle Aged; Mitral Valve; Myocardium; Nitroimidazoles

2019
New polyamine drugs as more effective antichagas agents than benznidazole in both the acute and chronic phases.
    European journal of medicinal chemistry, 2019, Feb-15, Volume: 164

    Topics: Acute Disease; Animals; Chagas Disease; Chronic Disease; Drug Design; Fluorenes; Humans; Microbodies; Nitroimidazoles; Polyamines; Solubility; Trypanocidal Agents; Trypanosoma cruzi

2019
Host-Derived Molecules as Novel Chagas Disease Biomarkers: Hypercoagulability Markers in Plasma.
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1955

    Topics: Biomarkers; Chagas Disease; Chronic Disease; Enzyme-Linked Immunosorbent Assay; Humans; Nitroimidazoles; Prognosis; Thrombin; Thrombophilia; Trypanocidal Agents; Trypanosoma cruzi

2019
Trypanosoma cruzi-Specific T-Cell Responses to Monitor Treatment Efficacy in Chronic Chagas Disease.
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1955

    Topics: Cells, Cultured; Chagas Disease; Chronic Disease; Humans; Immunity, Cellular; Immunoenzyme Techniques; Leukocytes, Mononuclear; Nitroimidazoles; Prognosis; T-Lymphocytes; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2019
Economic value of a therapeutic Chagas vaccine for indeterminate and Chagasic cardiomyopathy patients.
    Vaccine, 2019, 06-19, Volume: 37, Issue:28

    Topics: Cardiomyopathies; Chagas Disease; Chronic Disease; Cost-Benefit Analysis; Disease Progression; Humans; Nitroimidazoles; Trypanosoma cruzi; Vaccination; Vaccines

2019
Evaluation of the ELISA-F29 test as an early marker of therapeutic efficacy in adults with chronic Chagas disease.
    Revista do Instituto de Medicina Tropical de Sao Paulo, 2013, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Antibodies, Protozoan; Antigens, Protozoan; Case-Control Studies; Chagas Disease; Chronic Disease; Cohort Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Nifurtimox; Nitroimidazoles; Retrospective Studies; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi; Young Adult

2013
Benznidazole treatment in chronic children infected with Trypanosoma cruzi: serological and molecular follow-up of patients and identification of Discrete Typing Units.
    Acta tropica, 2013, Volume: 128, Issue:1

    Topics: Adolescent; Antibodies, Protozoan; Antiprotozoal Agents; Argentina; Chagas Disease; Child; Child, Preschool; Chronic Disease; DNA, Kinetoplast; DNA, Protozoan; Female; Follow-Up Studies; Genotype; Humans; Male; Nitroimidazoles; Nucleic Acid Hybridization; Rural Population; Treatment Outcome; Trypanosoma cruzi

2013
Towards a paradigm shift in the treatment of chronic Chagas disease.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:2

    Topics: Adolescent; Adult; Antibodies, Protozoan; Chagas Cardiomyopathy; Child; Chronic Disease; Disease Management; Drug Administration Schedule; Humans; Nifurtimox; Nitroimidazoles; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Severity of Illness Index; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2014
Synthesis and structure-activity relationships for extended side chain analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824).
    Journal of medicinal chemistry, 2015, Apr-09, Volume: 58, Issue:7

    Topics: Administration, Oral; Animals; Antitubercular Agents; Biological Availability; Chemistry Techniques, Synthetic; Chronic Disease; Disease Models, Animal; Humans; Male; Mice, Inbred BALB C; Mice, Inbred Strains; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Rats, Sprague-Dawley; Structure-Activity Relationship; Tuberculosis

2015
Hypoxic viable tissue in human chronic cerebral ischemia because of unilateral major cerebral artery steno-occlusive disease.
    Stroke, 2015, Volume: 46, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Brain Chemistry; Brain Ischemia; Cerebral Arterial Diseases; Cerebrovascular Circulation; Chronic Disease; Female; Humans; Hypoxia; Infarction, Middle Cerebral Artery; Male; Middle Aged; Nitroimidazoles; Oxygen Consumption; Oxygen Radioisotopes; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals

2015
Limited Ability of Posaconazole To Cure both Acute and Chronic Trypanosoma cruzi Infections Revealed by Highly Sensitive In Vivo Imaging.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:8

    Topics: Animals; Antifungal Agents; Chagas Disease; Chronic Disease; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Mice, SCID; Nitroimidazoles; Triazoles; Trypanocidal Agents; Trypanosoma cruzi

2015
Toxic Profile of Benznidazole in Patients with Chronic Chagas Disease: Risk Factors and Comparison of the Product from Two Different Manufacturers.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10

    Topics: Adult; Chagas Disease; Chronic Disease; Female; Humans; Male; Middle Aged; Nitroimidazoles; Prospective Studies; Risk Factors; Treatment Outcome

2015
New Scheme of Intermittent Benznidazole Administration in Patients Chronically Infected with Trypanosoma cruzi: a Pilot Short-Term Follow-Up Study with Adult Patients.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:2

    Topics: Adult; Chagas Disease; Chronic Disease; DNA, Kinetoplast; DNA, Satellite; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Liver; Male; Middle Aged; Nitroimidazoles; Pilot Projects; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma cruzi

2016
Synthesis and evaluation of pretomanid (PA-824) oxazolidinone hybrids.
    Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2

    Topics: Animals; Antitubercular Agents; Chronic Disease; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mycobacterium tuberculosis; Nitroimidazoles; Oxazolidinones; Tuberculosis

2016
The year in cardiology 2015: heart failure.
    European heart journal, 2016, Feb-01, Volume: 37, Issue:5

    Topics: Alcohol Drinking; Angioedema; Angiotensin-Converting Enzyme Inhibitors; Chagas Cardiomyopathy; Chronic Disease; Diabetes Mellitus, Type 2; Genetic Therapy; Heart Failure; Humans; Hypoglycemic Agents; Nitroimidazoles; Respiration, Artificial; Risk Factors; Sleep Apnea, Central; Trypanocidal Agents

2016
Altered Hypercoagulability Factors in Patients with Chronic Chagas Disease: Potential Biomarkers of Therapeutic Response.
    PLoS neglected tropical diseases, 2016, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Antiprotozoal Agents; Biomarkers; Chagas Disease; Chronic Disease; Drug Monitoring; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Thrombophilia; Treatment Outcome; Young Adult

2016
Longitudinal study of patients with chronic Chagas cardiomyopathy in Brazil (SaMi-Trop project): a cohort profile.
    BMJ open, 2016, 05-04, Volume: 6, Issue:5

    Topics: Aged; Biomarkers; Brazil; Chagas Cardiomyopathy; Chronic Disease; Disease Progression; Female; Follow-Up Studies; Heart Failure; Humans; Immunosuppressive Agents; Longitudinal Studies; Male; Middle Aged; Natriuretic Peptide, Brain; Nitroimidazoles; Peptide Fragments; Population Surveillance; Predictive Value of Tests; Prognosis; Prospective Studies; Quality of Life; Socioeconomic Factors

2016
Serological based monitoring of a cohort of patients with chronic Chagas disease treated with benznidazole in a highly endemic area of northern Argentina.
    Memorias do Instituto Oswaldo Cruz, 2016, May-24, Volume: 111, Issue:6

    Topics: Adult; Antibodies, Protozoan; Antigens, Protozoan; Argentina; Chagas Disease; Chronic Disease; Cohort Studies; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Prospective Studies; Time Factors; Trypanocidal Agents; Young Adult

2016
Efficacy of Lychnopholide Polymeric Nanocapsules after Oral and Intravenous Administration in Murine Experimental Chagas Disease.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:9

    Topics: Acute Disease; Administration, Intravenous; Administration, Oral; Animals; Chagas Disease; Chronic Disease; Delayed-Action Preparations; Disease Models, Animal; Drug Compounding; Humans; Lactones; Mice; Nanocapsules; Nitroimidazoles; Polyethylene Glycols; Sesquiterpenes; Survival Analysis; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2016
[The third and new face of Chagas disease].
    Bulletin de la Societe de pathologie exotique (1990), 2016, Volume: 109, Issue:3

    Topics: Adult; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Disease Progression; Humans; Neglected Diseases; Nitroimidazoles; Treatment Failure

2016
Benznidazole Use among Patients with Chronic Chagas' Cardiomyopathy in an Endemic Region of Brazil.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Aged; Brazil; Chagas Cardiomyopathy; Chronic Disease; Comorbidity; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Logistic Models; Male; Middle Aged; Nitroimidazoles; Socioeconomic Factors; Trypanocidal Agents

2016
Simvastatin Attenuates Endothelial Activation through 15-Epi-Lipoxin A4 Production in Murine Chronic Chagas Cardiomyopathy.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:3

    Topics: Animals; Anticholesteremic Agents; Arachidonate 5-Lipoxygenase; Chagas Cardiomyopathy; Chronic Disease; Disease Models, Animal; Drug Therapy, Combination; E-Selectin; Endothelium; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Lipoxins; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Myocardium; Nitroimidazoles; Parasitemia; Simvastatin; Survival Analysis; Trypanocidal Agents; Trypanosoma cruzi; Vascular Cell Adhesion Molecule-1

2017
Chronic Chagas cardiomyopathy: a review of the main pathogenic mechanisms and the efficacy of aetiological treatment following the BENznidazole Evaluation for Interrupting Trypanosomiasis (BENEFIT) trial.
    Memorias do Instituto Oswaldo Cruz, 2017, Volume: 112, Issue:3

    Topics: Animals; Chagas Cardiomyopathy; Chronic Disease; Clinical Trials as Topic; Disease Progression; Female; Humans; Latin America; Male; Middle Aged; Nitroimidazoles; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2017
Trypanosoma cruzi: Genetic diversity influences the profile of immunoglobulins during experimental infection.
    Experimental parasitology, 2009, Volume: 121, Issue:1

    Topics: Acute Disease; Animals; Chagas Disease; Chronic Disease; Enzyme-Linked Immunosorbent Assay; Female; Genetic Variation; Genotype; Immunoglobulin G; Mice; Nitroimidazoles; Phylogeny; Random Allocation; Time Factors; Trypanocidal Agents; Trypanosoma cruzi

2009
Efficacy of benznidazol treatment for asymptomatic chagasic patients from state of Rio Grande do Sul evaluated during a three years follow-up.
    Memorias do Instituto Oswaldo Cruz, 2009, Volume: 104, Issue:1

    Topics: Adult; Animals; Case-Control Studies; Chagas Disease; Chronic Disease; Cohort Studies; DNA, Kinetoplast; Enzyme-Linked Immunosorbent Assay; Female; Fluorescent Antibody Technique, Indirect; Follow-Up Studies; Humans; Male; Nitroimidazoles; Parasitemia; Polymerase Chain Reaction; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi; Young Adult

2009
Antioxidant therapy attenuates oxidative insult caused by benzonidazole in chronic Chagas' heart disease.
    International journal of cardiology, 2010, Nov-05, Volume: 145, Issue:1

    Topics: Antioxidants; Ascorbic Acid; Chagas Disease; Chronic Disease; Humans; Nitroimidazoles; Oxidative Stress; Thiobarbituric Acid Reactive Substances; Vitamin E

2010
Chagas' disease and its toll on the heart.
    European heart journal, 2009, Volume: 30, Issue:17

    Topics: Acute Disease; Arrhythmias, Cardiac; Brazil; Chagas Cardiomyopathy; Chronic Disease; Defibrillators, Implantable; Heart Failure; History, 20th Century; Humans; Nitroimidazoles; Nobel Prize; Trypanocidal Agents

2009
The BENEFIT trial: testing the hypothesis that trypanocidal therapy is beneficial for patients with chronic Chagas heart disease.
    Memorias do Instituto Oswaldo Cruz, 2009, Volume: 104 Suppl 1

    Topics: Animals; Chagas Cardiomyopathy; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Evidence-Based Medicine; Humans; Nitroimidazoles; Patient Selection; Pilot Projects; Trypanocidal Agents

2009
Treatment and seroconversion in a cohort of children suffering from recent chronic Chagas infection in Yoro, Honduras.
    Memorias do Instituto Oswaldo Cruz, 2009, Volume: 104, Issue:7

    Topics: Age Distribution; Animals; Antibodies, Protozoan; Chagas Disease; Child; Child, Preschool; Chronic Disease; Epidemiologic Methods; Female; Honduras; Humans; Immunoglobulin G; Infant; Insect Control; Male; Nitroimidazoles; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2009
Clinical and laboratory status of patients with chronic Chagas disease living in a vector-controlled area in Minas Gerais, Brazil, before and nine years after aetiological treatment.
    Memorias do Instituto Oswaldo Cruz, 2009, Volume: 104, Issue:8

    Topics: Adolescent; Adult; Antibodies, Protozoan; Brazil; Chagas Cardiomyopathy; Chagas Disease; Child; Chronic Disease; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; Male; Nitroimidazoles; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi; Young Adult

2009
Phenyl-alpha-tert-butyl-nitrone and benzonidazole treatment controlled the mitochondrial oxidative stress and evolution of cardiomyopathy in chronic chagasic Rats.
    Journal of the American College of Cardiology, 2010, Jun-01, Volume: 55, Issue:22

    Topics: Analysis of Variance; Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Cyclic N-Oxides; Disease Models, Animal; Disease Progression; Heart Function Tests; Hemodynamics; Lipid Peroxidation; Mitochondria, Heart; Nitroimidazoles; Oxidative Stress; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Trypanosoma cruzi

2010
Heart rate variability in chronic Chagas patients before and after treatment with benznidazole.
    Autonomic neuroscience : basic & clinical, 2010, Dec-08, Volume: 158, Issue:1-2

    Topics: Adult; Aged; Arrhythmias, Cardiac; Autonomic Nervous System Diseases; Chagas Disease; Chronic Disease; Drug Administration Schedule; Female; Heart Rate; Humans; Male; Middle Aged; Nitroimidazoles; Trypanocidal Agents; Young Adult

2010
Chagas disease: pushing through the pipeline.
    Nature, 2010, Jun-24, Volume: 465, Issue:7301

    Topics: Adult; Animals; Chagas Disease; Child; Chronic Disease; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Infant, Newborn; Lupus Erythematosus, Systemic; Molecular Targeted Therapy; Nitroimidazoles; Triazoles; Trypanocidal Agents; Trypanosoma cruzi; Young Adult

2010
Chagas disease 101.
    Nature, 2010, Jun-24, Volume: 465, Issue:7301

    Topics: Acute Disease; Animals; Carrier State; Chagas Disease; Chronic Disease; Clinical Trials as Topic; History, 16th Century; History, 19th Century; History, 20th Century; History, 21st Century; History, Ancient; Humans; Insect Vectors; Latin America; Neglected Diseases; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2010
Humoral immune response against P2β from Trypanosoma cruzi in persons with chronic Chagas disease: its relationship with treatment against parasites and myocardial damage.
    The American journal of tropical medicine and hygiene, 2011, Volume: 84, Issue:4

    Topics: Animals; Antibodies, Protozoan; Cardiomyopathies; Chagas Disease; Chronic Disease; Female; Humans; Immunity, Humoral; Male; Nifurtimox; Nitroimidazoles; Protozoan Proteins; Ribosomal Proteins; Trypanocidal Agents; Trypanosoma cruzi

2011
Synthesis and structure-activity relationships of varied ether linker analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5h-imidazo[2,1-b][1,3]oxazine (PA-824).
    Journal of medicinal chemistry, 2011, Oct-13, Volume: 54, Issue:19

    Topics: Acute Disease; Animals; Antitubercular Agents; Chronic Disease; Ethers; Humans; In Vitro Techniques; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium tuberculosis; Nitroimidazoles; Stereoisomerism; Structure-Activity Relationship; Tuberculosis, Pulmonary

2011
Hypercoagulability biomarkers in Trypanosoma cruzi -infected patients.
    Thrombosis and haemostasis, 2011, Volume: 106, Issue:4

    Topics: Adult; Biomarkers; Biomarkers, Pharmacological; Chagas Disease; Chronic Disease; Disease Progression; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Prothrombin; Risk; Thrombin; Thromboembolism; Thrombophilia; Trypanosoma cruzi

2011
Impact of aetiological treatment on conventional and multiplex serology in chronic Chagas disease.
    PLoS neglected tropical diseases, 2011, Volume: 5, Issue:9

    Topics: Adult; Antibodies, Protozoan; Antiprotozoal Agents; Argentina; Chagas Disease; Chronic Disease; Drug Monitoring; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Trypanosoma cruzi

2011
Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824).
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Acute Disease; Amides; Animals; Antitubercular Agents; Biological Availability; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbamates; Chronic Disease; Dogs; Humans; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Models, Molecular; Mycobacterium tuberculosis; Nitroimidazoles; Piperazines; Rats; Solubility; Stereoisomerism; Structure-Activity Relationship; Tuberculosis, Pulmonary; Urea

2012
Serological profiles and evaluation of parasitaemia by PCR and blood culture in individuals chronically infected by Trypanosoma cruzi treated with benzonidazole.
    Tropical medicine & international health : TM & IH, 2012, Volume: 17, Issue:3

    Topics: Adult; Age Factors; Antibodies, Protozoan; Chagas Disease; Chronic Disease; DNA, Protozoan; Enzyme-Linked Immunosorbent Assay; Female; Fluorescent Antibody Technique, Indirect; Humans; Male; Nitroimidazoles; Parasitemia; Polymerase Chain Reaction; Retrospective Studies; Treatment Failure; Trypanocidal Agents; Trypanosoma cruzi; Young Adult

2012
Safety of benznidazole use in the treatment of chronic Chagas' disease.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:5

    Topics: Adolescent; Adult; Aged; Algorithms; Antiprotozoal Agents; Chagas Disease; Chronic Disease; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Humans; Male; Middle Aged; Models, Statistical; Nitroimidazoles; Young Adult

2012
Cardiomyopathy prognosis after benznidazole treatment in chronic canine Chagas' disease.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:8

    Topics: Animal Experimentation; Animals; Antiprotozoal Agents; Chagas Cardiomyopathy; Chronic Disease; DNA, Protozoan; Dog Diseases; Dogs; Heart; Nitroimidazoles; Parasitemia; Prognosis; Trypanosoma cruzi

2012
Inhibitory receptors are expressed by Trypanosoma cruzi-specific effector T cells and in hearts of subjects with chronic Chagas disease.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Adult; Antigens, CD; Antigens, Protozoan; CD4-Positive T-Lymphocytes; Chagas Disease; Chronic Disease; CTLA-4 Antigen; Gene Expression Regulation; Heart; Humans; Interferon-gamma; Leukocyte Immunoglobulin-like Receptor B1; Male; Middle Aged; Myocarditis; Nitroimidazoles; Receptors, Immunologic; Species Specificity; Trypanosoma cruzi

2012
Seronegative conversion after incomplete benznidazole treatment in chronic Chagas disease.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2012, Volume: 106, Issue:10

    Topics: Adult; Chagas Disease; Chronic Disease; Drug Administration Schedule; Female; Humans; Male; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2012
Myocardial scars correlate with eletrocardiographic changes in chronic Trypanosoma cruzi infection for dogs treated with Benznidazole.
    Tropical medicine & international health : TM & IH, 2013, Volume: 18, Issue:1

    Topics: Animals; Atrioventricular Block; Chagas Disease; Chronic Disease; Cicatrix; Collagen; Dogs; Drug Resistance; Electrocardiography; Fibrosis; Heart Atria; Myocardium; Nitroimidazoles; Prospective Studies; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2013
Benznidazole-related adverse drug reactions and their relationship to serum drug concentrations in patients with chronic chagas disease.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:1

    Topics: Adolescent; Adult; Chagas Disease; Chronic Disease; Drug Administration Schedule; Drug Dosage Calculations; Drug Monitoring; Female; Humans; Male; Middle Aged; Nitroimidazoles; Prospective Studies; Trypanocidal Agents; Trypanosoma cruzi

2013
Chronic renal hypoxia after acute ischemic injury: effects of L-arginine on hypoxia and secondary damage.
    American journal of physiology. Renal physiology, 2003, Volume: 284, Issue:2

    Topics: Acute Kidney Injury; Animals; Arginine; Chronic Disease; Disease Progression; Hypoxia; Ischemia; Kidney; Kidney Diseases; Kidney Failure, Chronic; Male; Nephrectomy; Nitroimidazoles; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Time Factors

2003
Treatment with benznidazole during the chronic phase of experimental Chagas' disease decreases cardiac alterations.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:4

    Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Heart; Humans; Male; Mice; Mice, Inbred BALB C; Myocarditis; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2005
Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2.
    Gut, 2005, Volume: 54, Issue:12

    Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Aorta, Thoracic; Carboxypeptidases; Cell Hypoxia; Cells, Cultured; Chronic Disease; Disease Models, Animal; Female; Hepatitis C, Chronic; Hepatocytes; Humans; Immunoenzyme Techniques; Liver; Liver Cirrhosis; Male; Nitroimidazoles; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation; Vasodilation

2005
Summaries for patients. Long-term outcomes of treating nonacute Chagas disease with benznidazole.
    Annals of internal medicine, 2006, May-16, Volume: 144, Issue:10

    Topics: Adult; Animals; Antibodies, Protozoan; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Disease Progression; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Prognosis; Sensitivity and Specificity; Trypanocidal Agents; Trypanosoma cruzi

2006
Manifestations of Chagas disease (American trypanosomiasis) in patients with HIV/AIDS.
    Annals of tropical medicine and parasitology, 2007, Volume: 101, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Brazil; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Female; HIV Infections; Humans; Male; Meningoencephalitis; Middle Aged; Nitroimidazoles; Parasitemia; Trypanocidal Agents; Xenodiagnosis

2007
Treatment with benznidazole or thioridazine in the chronic phase of experimental Chagas disease improves cardiopathy.
    International journal of antimicrobial agents, 2007, Volume: 29, Issue:6

    Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Disease Models, Animal; Drug Evaluation, Preclinical; Electrocardiography; Mice; Nitroimidazoles; Thioridazine; Trypanocidal Agents

2007
Benznidazole therapy during acute phase of Chagas disease reduces parasite load but does not prevent chronic cardiac lesions.
    Parasitology research, 2008, Volume: 103, Issue:2

    Topics: Acute Disease; Animals; Chagas Disease; Chronic Disease; Drug Resistance; Heart; Humans; Mice; Myocardium; Nitroimidazoles; Parasitemia; Trypanocidal Agents; Trypanosoma cruzi

2008
[Benznidazole and chronic Chagas disease].
    Medicina, 1984, Volume: 44, Issue:1

    Topics: Chagas Disease; Chronic Disease; Humans; Nitroimidazoles; Trypanocidal Agents

1984
The use of 2-substituted 5-nitroimidazoles in the treatment of chronic murine Trypanosoma brucei infections with central nervous system involvement.
    Zeitschrift fur Parasitenkunde (Berlin, Germany), 1984, Volume: 70, Issue:6

    Topics: Animals; Antiprotozoal Agents; Brain; Chronic Disease; Drug Therapy, Combination; Female; Mice; Mice, Inbred Strains; Nitroimidazoles; Rodent Diseases; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1984
The use of the 2 substituted 5-nitroimidazole, Fexinidazole (Hoe 239) in the treatment of chronic T. brucei infections in mice.
    Zeitschrift fur Parasitenkunde (Berlin, Germany), 1983, Volume: 69, Issue:5

    Topics: Animals; Antiprotozoal Agents; Chronic Disease; Diminazene; Drug Therapy, Combination; Female; Mice; Mice, Inbred Strains; Nitroimidazoles; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1983
Antibodies inhibiting Trypanosoma cruzi trans-sialidase activity in sera from human infections.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:6

    Topics: Acute Disease; Animals; Antibodies, Protozoan; Antigens, Protozoan; Chagas Disease; Chronic Disease; Female; Glycoproteins; Humans; Immune Sera; Infant, Newborn; Neuraminidase; Neutralization Tests; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

1994
Use of Trypanosoma cruzi purified glycoprotein (GP57/51) or trypomastigote-shed antigens to assess cure for human Chagas' disease.
    The American journal of tropical medicine and hygiene, 1993, Volume: 49, Issue:5

    Topics: Acute Disease; Adsorption; Adult; Animals; Antibodies, Protozoan; Antibody Specificity; Antigens, Protozoan; Chagas Disease; Child; Chronic Disease; Cross Reactions; Cysteine Endopeptidases; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Follow-Up Studies; Glycoproteins; Humans; Middle Aged; Nifurtimox; Nitroimidazoles; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

1993
Should benznidazole be used in chronic Chagas' disease?
    Lancet (London, England), 1997, Mar-01, Volume: 349, Issue:9052

    Topics: Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Follow-Up Studies; Humans; Neoplasms; Nitroimidazoles; Trypanocidal Agents

1997
Recipients and donors of bone marrow transplants suffering from Chagas' disease: management and preemptive therapy of parasitemia.
    Bone marrow transplantation, 1998, Volume: 21, Issue:4

    Topics: Adult; Bone Marrow Transplantation; Chagas Disease; Chronic Disease; Female; Humans; Immunosuppression Therapy; Leukemia; Lymphoma, Non-Hodgkin; Male; Middle Aged; Nitroimidazoles; Parasitemia; Recurrence; Transplantation, Autologous; Transplantation, Homologous; Trypanocidal Agents

1998
Higher incidence of malignant neoplasms after heart transplantation for treatment of chronic Chagas' heart disease.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1998, Volume: 17, Issue:4

    Topics: Adult; Carcinoma, Squamous Cell; Chagas Cardiomyopathy; Chemoprevention; Chronic Disease; Cocarcinogenesis; Cyclosporine; Female; Follow-Up Studies; Heart Failure; Heart Transplantation; Humans; Immunosuppressive Agents; Incidence; Lung Diseases; Lymphoproliferative Disorders; Male; Mutagens; Neoplasms; Neurilemmoma; Nitroimidazoles; Recurrence; Sarcoma, Kaposi; Skin Neoplasms; Survival Rate; Trypanocidal Agents

1998
[Treatment of chronic Chagas' disease. Is the etiological treatment effective?].
    Arquivos brasileiros de cardiologia, 1998, Volume: 71, Issue:4

    Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Humans; Nitroimidazoles; Treatment Outcome; Trypanocidal Agents

1998
Radiobiological and immunohistochemical assessment of hypoxia in human melanoma xenografts: acute and chronic hypoxia in individual tumours.
    International journal of radiation biology, 1999, Volume: 75, Issue:11

    Topics: Acute Disease; Animals; Cell Hypoxia; Cell Separation; Cell Survival; Chronic Disease; Dose-Response Relationship, Radiation; Female; Humans; Immunohistochemistry; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Radiobiology; Staining and Labeling; Transplantation, Heterologous; Tumor Cells, Cultured

1999
Activities of the triazole derivative SCH 56592 (posaconazole) against drug-resistant strains of the protozoan parasite Trypanosoma (Schizotrypanum) cruzi in immunocompetent and immunosuppressed murine hosts.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:1

    Topics: Acute Disease; Animals; Chagas Disease; Chronic Disease; Drug Resistance; Female; Immunocompetence; Immunosuppression Therapy; Mice; Nitroimidazoles; Triazoles; Trypanocidal Agents; Trypanosoma cruzi

2000
Polymerase chain reaction (PCR) as a laboratory tool for the evaluation of the parasitological cure in Chagas disease after specific treatment.
    Medicina, 1999, Volume: 59 Suppl 2

    Topics: Chagas Disease; Chronic Disease; DNA, Protozoan; Evaluation Studies as Topic; Humans; Nitroimidazoles; Polymerase Chain Reaction; Sensitivity and Specificity; Treatment Outcome; Trypanocidal Agents

1999
Efficacy of the bisbenzylisoquinoline alkaloids in acute and chronic Trypanosoma cruzi murine model.
    International journal of antimicrobial agents, 2000, Volume: 13, Issue:3

    Topics: Acute Disease; Administration, Oral; Alkaloids; Animals; Benzylisoquinolines; Chagas Disease; Chronic Disease; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Immunoblotting; Isoquinolines; Male; Mice; Mice, Inbred BALB C; Nitroimidazoles; Parasitemia; Trypanocidal Agents

2000
Chagas' disease.
    Lancet (London, England), 2001, Jul-07, Volume: 358, Issue:9275

    Topics: Adolescent; Adult; Chagas Cardiomyopathy; Chagas Disease; Child; Chronic Disease; Humans; Nitroimidazoles; Risk Factors; Trypanocidal Agents

2001
Experimental treatment of chronic Trypanosoma cruzi infection in mice with 2-n-propylquinoline.
    Phytotherapy research : PTR, 2001, Volume: 15, Issue:7

    Topics: Animals; Chagas Disease; Chronic Disease; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Male; Mice; Mice, Inbred BALB C; Nitroimidazoles; Phytotherapy; Plant Extracts; Quinolines; Rutaceae; Trypanocidal Agents; Trypanosoma cruzi

2001
[Treatment of chronic amebiasis with nitrimidazole (author's transl)].
    Revista medica de Chile, 1976, Volume: 104, Issue:11

    Topics: Adolescent; Adult; Aged; Body Weight; Child; Child, Preschool; Chronic Disease; Drug Evaluation; Dysentery, Amebic; Female; Humans; Male; Middle Aged; Nimorazole; Nitroimidazoles; Tablets

1976
Evaluation of the mutagenic potential of the antichagasic drug Rochagan in healthy and chagasic rodents.
    Mutation research, 1991, Volume: 259, Issue:2

    Topics: Acute Disease; Animals; Bone Marrow; Bone Marrow Cells; Chagas Disease; Chromosome Aberrations; Chromosomes; Chronic Disease; Dose-Response Relationship, Drug; Mice; Mice, Inbred BALB C; Micronucleus Tests; Nitroimidazoles; Rats; Rats, Inbred Strains; Time Factors; Trypanocidal Agents

1991
Shift of excretory-secretory immunogens of Trypanosoma cruzi during human Chagas' disease.
    Infection and immunity, 1991, Volume: 59, Issue:6

    Topics: Acute Disease; Animals; Antibodies, Protozoan; Antigens, Protozoan; Chagas Disease; Chronic Disease; Electrophoresis, Polyacrylamide Gel; Humans; Immunoblotting; Nitroimidazoles; Rabbits; Trypanocidal Agents; Trypanosoma cruzi

1991