Page last updated: 2024-08-21

azomycin and Carcinoma, Epidermoid

azomycin has been researched along with Carcinoma, Epidermoid in 124 studies

Research

Studies (124)

TimeframeStudies, this research(%)All Research%
pre-199030 (24.19)18.7374
1990's26 (20.97)18.2507
2000's37 (29.84)29.6817
2010's30 (24.19)24.3611
2020's1 (0.81)2.80

Authors

AuthorsStudies
Hansen, CR; Johansen, J; Kallehauge, J; Mortensen, LS; Overgaard, J; Primdahl, H; Saksø, M1
Baker, LCJ; Bhide, SA; Box, C; d'Arcy, JA; Dunlop, A; Eccles, SA; Harrington, KJ; Hopkinson, G; Koh, DM; Leach, MO; Mcquaid, D; Newbold, KL; Nutting, CM; Panek, R; Richardson, C; Riddell, AM; Robinson, SP; Schmidt, MA; Welsh, L; Wong, KH1
Bol, A; Di Perri, D; Geets, X; Hanin, FX; Janssens, G; Labar, D; Lee, JA; Robert, A; Sterpin, E1
Dadgar, S; Rajaram, N; Troncoso, JR1
Busk, M; Horsman, MR; Iversen, AB; Jakobsen, S; Ji, X; Lee, DY; Mortensen, LS; Nordsmark, M; Overgaard, J; Raleigh, JR1
Baumann, M; Brüchner, K; Gurtner, K; Helbig, L; Hess-Stumpp, H; Koi, L; Pruschy, M; Unterschemmann, K; Yaromina, A; Zips, D1
Bol, A; Differding, S; Grégoire, V; Hanin, FX; Labar, D; Lee, JA; Servagi-Vernat, S1
Giraud, P; Servagi-Vernat, S1
Bollineni, VR; Brouwer, CL; Groen, HJ; Halmos, GB; Koole, MJ; Langendijk, JA; Oosting, SF; Pruim, J; Steenbakkers, RJ; Vlasman, R; Widder, J; Wiegman, EM1
Bol, A; Differding, S; Grégoire, V; Hanin, FX; Labar, D; Lee, JA; Servagi-Vernat, S; Sterpin, E1
Galoforo, S; Grills, IS; Kane, JL; Krueger, SA; Marples, B; Wilson, GD; Wobb, J1
Bollineni, VR; Bruine de Bruin, L; de Bock, GH; Halmos, GB; Langendijk, JA; Pruim, J; Schuuring, E; Slagter-Menkema, L; Steenbakkers, RJ; van der Laan, BF; van der Wal, JE; van Hemel, BM; Wachters, JE1
Brown, KR; Goldstein, DP; Gu, Y; Hunter, FW; Joshi, N; Ketela, T; Koritzinsky, M; Moffat, J; Rischin, D; Shalev, Z; Solomon, B; Sreebhavan, S; Vellanki, RN; Wang, J; Weinreb, I; Wilson, WR; Wouters, BG; Young, RJ1
Fujibayashi, Y; Harada, R; Inubushi, M; Koizumi, M; Obata, T; Saga, T; Tanimoto, K; Uno, T; Yoshikawa, K; Zhang, MR1
Baumann, M; Mönnich, D; Thorwarth, D; Wack, LJ; Yaromina, A; Zips, D1
Busk, M; Horsman, MR; Overgaard, J1
Abrams, DN; Kumar, P; McEwan, AJ; Postema, EJ; Riauka, TA; Richmond, DA; Wiebe, LI1
Baumann, M; Eckardt, A; Eicheler, W; Schuetze, C; Thames, H; Yaromina, A; Zips, D1
Hoogsteen, IJ; Kaanders, JH; Lok, J; Marres, HA; Rijken, PF; Takes, RP; van der Kogel, AJ1
Busk, M; Bussink, J; Hansen, KV; Horsman, MR; Jakobsen, S; Overgaard, J; van der Kogel, A1
Baumann, M; Meyer, S; Mueller-Klieser, W; Quennet, V; Shakirin, G; Walenta, S; Yaromina, A; Zips, D1
Baumann, M; Flentje, M; Jakob, PM; Melkus, G; Mörchel, P; Yaromina, A; Zips, D1
Baumann, M; Dörfler, A; Eicheler, W; Hering, S; Leichtner, T; Thames, H; Yaromina, A; Zhou, X; Zips, D1
Baumann, M; Beuthien-Baumann, B; Bussink, J; Eicheler, W; Krause, M; Rijken, P; Santiago, A; van der Kogel, AJ; Yaromina, A1
Bachtiary, B; Dimopoulos, J; Dudczak, R; Georg, D; Karanikas, G; Kletter, K; Kommata, S; Lukic, D; Pötter, R; Schmid, MP; Schuetz, M1
Busk, M; Horsman, MR; Jakobsen, S; Munk, OL; Overgaard, J; Skals, M; Steiniche, T; Wang, T1
Baumann, M; Boeke, S; Kroeber, T; Meinzer, A; Thames, H; Yaromina, A; Zips, D1
Betts, G; Bonington, SC; Buckley, DL; Donaldson, SB; Homer, JJ; Kershaw, LE; Slevin, NJ; Valentine, H; West, CM1
Cabrera, AR; Fu, Z; Ma, L; Sun, X; Xie, P; Yang, Y; Yu, J; Yue, J; Zhao, S; Zheng, J1
Busk, M; Horsman, MR; Jakobsen, S; Mueller-Klieser, W; Overgaard, J; Steiniche, T; Walenta, S1
Bezak, E; Filip, SM; Marcu, LG1
Bussink, J; Hoogsteen, IJ; Kaanders, JH; Lok, J; Marres, HA; Rijken, PF; van den Hoogen, FJ1
Bartlett, R; Carlin, S; Humm, JL; McCall, KC; Reese, M1
Bussink, J; Grénman, R; Iida, M; Kaanders, JH; Span, PN; Stegeman, H; van der Kogel, AJ; Verheijen, MM; Waaijer, SJ; Wheeler, DL1
Baumann, M; Böke, S; Helbig, L; Koi, L; Sriramareddy, SN; Thames, HD; Yaromina, A; Zips, D1
Alsner, J; Busk, M; Jakobsen, S; Johansen, J; Kallehauge, J; Lassen, P; Mortensen, LS; Nordsmark, M; Overgaard, J; Petersen, H; Petersen, J; Primdahl, H; Sørensen, BS; Theil, J; Toustrup, K1
Dierckx, RA; Halmos, GB; Langedijk, JA; Pruim, J; Roodenburg, JL; van der Laan, BF; Wedman, J1
Balm, AJ; Begg, AC; Blijweert, E; Blommestijn, G; Delaere, P; Haustermans, KM; Hoebers, FJ; Hofland, I; Janssen, HL; Raleigh, JA; Sciot, R; Semenza, GL; Sprong, D; van Velthuysen, ML; Varia, MA1
Bennewith, KL; Durand, RE; Raleigh, JA1
Bussink, J; de Wilde, PC; Kaanders, JH; Ljungkvist, AS; Marres, HA; Pop, LA; Raleigh, JA; van den Hoogen, FJ; van der Kogel, AJ; Wijffels, KI1
Eskola, O; Grönroos, T; Lehtiö, K; Minn, H; Nyman, S; Oikonen, V; Roivainen, A1
Airley, RE; Davidson, SE; Harris, AL; Hunter, RD; Loncaster, J; Raleigh, JA; Stratford, IJ; West, CM1
Bussink, J; Kaanders, JH; van der Kogel, AJ2
Azuma, Y; Chou, SC; Lininger, RA; Murphy, BJ; Raleigh, JA; Varia, MA1
Balm, AJ; Begg, AC; Goethals, L; Haustermans, KM; Hoebers, FJ; Janssen, HL; Sprong, D; Stratford, IJ; Williams, KJ1
Bennewith, KL; Durand, RE1
Ahmed, SU; Furuichi, S; Hori, H; Kan, S; Kasai, S; Nagasawa, H; Okamoto, M; Oshikawa, T; Sasai, A; Sato, M; Tano, T; Uto, Y1
Baumann, M; Eicheler, W; Hessel, F; Hölscher, T; Krause, M; Petersen, C; Rosner, A; Thames, HD; Yaromina, A; Zips, D1
Hoogsteen, IJ; Kaanders, JH; Marres, HA; Peeters, WJ; Rijken, PF; van den Hoogen, FJ; van der Kogel, AJ1
Hori, H; Ito, M; Nagasawa, H; Ogino, H; Shibamoto, Y; Sugie, C; Suzuki, H; Uto, Y1
Gotoh, K; Hori, H; Kinashi, Y; Maruhashi, A; Masunaga, S; Nagasawa, H; Nagata, K; Ono, K; Sakurai, Y; Suzuki, M; Uto, Y1
Boerman, OC; Bussink, J; Kaanders, JH; Laverman, P; Lok, J; Oyen, WJ; Philippens, M; Troost, EG; van der Kogel, AJ1
Balm, A; Barbé, B; Begg, AC; De Schutter, H; Gregoire, V; Haustermans, K; Mahy, P; Nuyts, S; Spaepen, M; Vander Poorten, V1
Aquino-Parsons, C; Durand, RE1
Baumann, M; Eicheler, W; Haase, M; Krause, M; Mueller-Klieser, W; Petersen, C; Quennet, V; Raleigh, JA; Rosner, A; Thames, HD; Walenta, S; Yaromina, A; Zips, D1
Kaanders, JH; Marres, HA; Peters, JP; Rijken, PF; van der Kogel, AJ; Wijffels, KI1
Le, QT1
Dobritz, M; Grosu, AL; Jacob, V; Machulla, HJ; Molls, M; Piert, M; Reischl, G; Röper, B; Schwaiger, M; Souvatzoglou, M; Wester, HJ; Wiedenmann, N1
Busk, M; Bussink, J; Horsman, MR; Jakobsen, S; Keiding, S; Overgaard, J; van der Kogel, AJ1
Christian, N; De Bast, M; Geets, X; Gillart, J; Grégoire, V; Labar, D; Lee, J; Levêque, P; Lonneux, M; Mahy, P1
Byhardt, RW; Cox, JD; Greenberg, M; Komaki, R1
Ando, K; Furukawa, S; Hiraoka, T; Kanai, T; Kawachi, K; Koike, S; Majima, H1
Awwad, HK; Barsoum, M; El Badawy, S; El Baki, HA; El Merzabani, M; Ezzat, S; Omar, S; Zaki, A1
Hansen, HH; Kjaer, M; Panduro, J; Wolff-Jensen, J1
McGregor, IA; Sleigh, JD; Sweeney, G; Watson, JD1
Anderson, PJ; Bennett, MH; Dische, S; Saunders, MI1
Cridland, S; Sealy, R1
Demange, L; Froissart, D; Nguyen, TD; Panis, X1
Blekkenhorst, G; Cridland, S; Korrubel, J; Sealy, R1
Abd El Baki, H; Abd El Moneim, H; Awwad, HK; El Merzabani, M; Farag, HI; Omar, S1
Omura, M1
Kishino, Y1
Okada, S; Sakamoto, K; Takada, C; Takahashi, M; Yasunaga, T1
Ho, KC; Kun, LE; Moulder, JE1
Carella, RJ; Concannon, JP; Perez, CA; Phillips, TL; Simpson, JR1
Hansen, HS; Kamieniecka, Z; Melgaard, B; Paulson, OB; Pedersen, AG; Tang, X; Trojaborg, W1
Arcangeli, G; Chaplain, G; Gonzalez, D; Horiot, JC; Svoboda, V; Van den Bogaert, W; van der Schueren, E1
Aritake, S; Sakamoto, K1
Dawes, PJ; Henk, JM; Moore, JL; Paterson, IC1
Maimonis, P; Michaels, HB; Sedlacek, R; Suit, HD1
Moore, JL; Newman, H; Paterson, IC; Venables, S1
Fazekas, JT; Goodman, RL; McLean, CJ1
Abe, M; Iwai, H; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T; Suzuki, T; Takagi, T1
Tada, T1
Cowan, DS; Matejovic, JF; McClelland, RA; Rauth, AM1
Abe, M; Kitakabu, Y; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T; Takahashi, M1
Abe, M; Ishigaki, T; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T1
Abe, M; Iwai, H; Matsuno, E; Sasai, K; Shibamoto, Y1
Abe, M; Iwai, H; Murata, R; Oya, N; Shibamoto, Y; Shibata, T; Sugiyama, T1
Hori, H; Inayama, S; Mori, T; Murayama, C; Nagasawa, H; Nakajima, T; Onoyama, Y; Tada, T1
Chapman, JD; Golberg, LE; Groshar, D; Hoskinson, M; Mannan, RH; McEwan, AJ; Mercer, JR; Parliament, MB; Urtasun, RC; Wiebe, LI1
Abe, M; Hiraoka, M; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T; Takagi, T1
Scobie, M; Threadgill, MD; Wood, PJ1
Akuta, K; Kinashi, Y; Masunaga, S; Ono, K; Suzuki, M1
Adams, GE; Horsman, MR; Khalil, AA; Overgaard, J; Steinberg, F; Stratford, IJ; Streffer, C; Wood, PJ1
Calkins, DP; Kennedy, AS; Novotny, DB; Perez, GM; Raleigh, JA; Thrall, DE; Varia, MA1
Bellotti, G; Bocchi, EA; Fiorelli, A; Higuchi, ML; Jatene, A; Pileggi, F; Stolf, N; Uip, D; Vieira, ML1
Ballenger, CA; Calkins-Adams, DP; Fowler, WC; Novotny, DB; Raleigh, JA; Rinker, LH; Varia, MA; Weissler, MC1
Bussink, J; Hodgkiss, RJ; Kaanders, JH; Marres, HA; Peters, JP; Rijken, PF; van der Kogel, AJ1
Ballenger, CA; Calkins-Adams, DP; Chou, SC; Novotny, DB; Raleigh, JA; Varia, MA1
Begg, AC; Geboes, K; Haustermans, K; Hofland, I; Raleigh, J; Van de Pavert, L; Varia, M1
Bussink, J; de Wilde, PC; Kaanders, JH; Marres, HA; Raleigh, JA; Rijken, PF; van den Hoogen, FJ; van der Kogel, AJ; Wijffels, KI1
Aquino-Parsons, C; Durand, RE; Luo, C; Olive, PL; Raleigh, JA1
Bussink, J; Denekamp, J; Ljungkvist, AS; Raleigh, JA; Rijken, PF; Van Der Kogel, AJ1
Bono, EL; Chou, SC; Raleigh, JA; Thrall, DE; Varia, MA1
Banáth, JP; Luo, CM; Olive, PL1
Guérin, RA1
Bleehen, NM; Owen, LN; White, RA; Workman, P1
Dische, S1
Suwiński, J; Watras, J; Wideł, M1
Fowler, JF; Hill, SA1
Coleman, CN; Cosmatos, D; Davis, LW; Lee, DJ; Marcial, VA; Phillips, TL; Rubin, P; Wasserman, TH1
Charreau, I; Chassagne, D; Eschwege, F; Malaise, EP; Sancho-Garnier, H2
Brown, DQ; Curran, WJ; Evans, SM; Hanks, G; Helfand, S; LaCreta, F; VanWinkle, T1
Coleman, N; Cosmatos, D; Davis, L; Lee, DJ; Marcial, V; Phillips, T; Stetz, J; Wasserman, TH1
Abe, M; Fushiki, M; Iwai, H; Nishimoto, S; Sasai, K; Shibamoto, Y; Suyama, S; Takahashi, M; Yukawa, Y1
Bleehen, NM; Newman, HF; Smithen, CE; Ward, R; Workman, P1
Wagner, W1
abd el Baki, H; Akoush, H; Awwad, HK; el Badawy, S; el Moneim Osman, A; Fairchild, K; Zaghloul, M1
Bennett, MH; Des Rochers, C; Dische, S; Dunphy, EP; Minchinton, AI; Saunders, MI; Stratford, MR; Wardman, P1

Reviews

5 review(s) available for azomycin and Carcinoma, Epidermoid

ArticleYear
[Metabolic tailoring in radiotherapy for head and neck cancer].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2014, Volume: 18, Issue:5-6

    Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Clinical Trials as Topic; Diffusion Magnetic Resonance Imaging; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Misonidazole; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Image-Guided; Tumor Burden

2014
The role of PET imaging in overcoming radiobiological challenges in the treatment of advanced head and neck cancer.
    Cancer treatment reviews, 2012, Volume: 38, Issue:3

    Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Cell Proliferation; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Nitroimidazoles; Positron-Emission Tomography; Radioisotopes; Radiotherapy, Image-Guided; Squamous Cell Carcinoma of Head and Neck

2012
Alternative PET tracers in head and neck cancer. A review.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2013, Volume: 270, Issue:10

    Topics: Amino Acids; Antibodies, Monoclonal; Carbon Radioisotopes; Carcinoma, Squamous Cell; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Misonidazole; Nitroimidazoles; Nucleosides; Positron-Emission Tomography; Radiopharmaceuticals

2013
Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2003, Volume: 67, Issue:1

    Topics: Antigens, Neoplasm; Biomarkers, Tumor; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; DNA-Binding Proteins; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Neoplasm Proteins; Nitroimidazoles; Nuclear Proteins; Oxygen; Radiation-Sensitizing Agents; Transcription Factors; Treatment Outcome; Vascular Endothelial Growth Factor A

2003
Radiosensitizers in the treatment of squamous cell carcinoma of the head and neck.
    Clinical otolaryngology and allied sciences, 1977, Volume: 2, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Hypoxia; Metronidazole; Mice; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents

1977

Trials

21 trial(s) available for azomycin and Carcinoma, Epidermoid

ArticleYear
Hypoxia-guided adaptive radiation dose escalation in head and neck carcinoma: a planning study.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:7

    Topics: Aged; Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Female; Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy Planning, Computer-Assisted; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed

2015
Prognostic value of PET/CT with (18)F-fluoroazomycin arabinoside for patients with head and neck squamous cell carcinomas receiving chemoradiotherapy.
    Annals of nuclear medicine, 2016, Volume: 30, Issue:3

    Topics: Carcinoma, Squamous Cell; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Prognosis; Squamous Cell Carcinoma of Head and Neck

2016
Initial results of hypoxia imaging using 1-alpha-D: -(5-deoxy-5-[18F]-fluoroarabinofuranosyl)-2-nitroimidazole ( 18F-FAZA).
    European journal of nuclear medicine and molecular imaging, 2009, Volume: 36, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Female; Fluorine Radioisotopes; Glioma; Head and Neck Neoplasms; Humans; Hypoxia; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Young Adult

2009
Evaluating repetitive 18F-fluoroazomycin-arabinoside (18FAZA) PET in the setting of MRI guided adaptive radiotherapy in cervical cancer.
    Acta oncologica (Stockholm, Sweden), 2010, Volume: 49, Issue:7

    Topics: Adaptation, Biological; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Nitroimidazoles; Periodicity; Pilot Projects; Positron-Emission Tomography; Radiography; Radiotherapy Dosage; Radiotherapy, Computer-Assisted; Uterine Cervical Neoplasms

2010
FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: results from the DAHANCA 24 trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 105, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Lymph Nodes; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Prognosis; Tomography, X-Ray Computed

2012
Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer.
    Cancer research, 2002, Dec-01, Volume: 62, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Carbon Dioxide; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Proteins; Niacinamide; Nitroimidazoles; Oxygen; Predictive Value of Tests; Treatment Outcome

2002
Quantifying tumour hypoxia with fluorine-18 fluoroerythronitroimidazole ([18F]FETNIM) and PET using the tumour to plasma ratio.
    European journal of nuclear medicine and molecular imaging, 2003, Volume: 30, Issue:1

    Topics: Blood Flow Velocity; Carcinoma, Squamous Cell; Cell Hypoxia; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Muscle, Skeletal; Nitroimidazoles; Oxygen Radioisotopes; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed

2003
The fate of hypoxic (pimonidazole-labelled) cells in human cervix tumours undergoing chemo-radiotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 80, Issue:2

    Topics: Adult; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Combined Modality Therapy; Female; Humans; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Spheroids, Cellular; Uterine Cervical Neoplasms

2006
Determination of tumour hypoxia with [18F]EF3 in patients with head and neck tumours: a phase I study to assess the tracer pharmacokinetics, biodistribution and metabolism.
    European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:7

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypoxia; Laryngeal Neoplasms; Male; Middle Aged; Nitroimidazoles; Pharyngeal Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution

2008
Misonidazole combined with radiotherapy in the treatment of inoperable squamous cell carcinoma of the lung. A double-blind randomized trial.
    Cancer, 1983, Jul-01, Volume: 52, Issue:1

    Topics: Aged; Carcinoma, Squamous Cell; Double-Blind Method; Esophagitis; Humans; Lung Neoplasms; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Placebos; Pneumonia; Radiation Injuries; Radiotherapy Dosage; Random Allocation; Vomiting

1983
A study of the effect of misonidazole in conjunction with radiotherapy for the treatment of head and neck cancer. MRC working party on misonidazole in head and neck cancer.
    The British journal of radiology, 1984, Volume: 57, Issue:679

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Radiotherapy; Radiotherapy Dosage; Random Allocation

1984
Successful prophylaxis with tinidazole of infection after major head and neck surgery for malignant disease.
    British journal of plastic surgery, 1984, Volume: 37, Issue:1

    Topics: Aged; Bacteria; Carcinoma, Squamous Cell; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Nitroimidazoles; Pharyngeal Neoplasms; Prospective Studies; Surgical Wound Infection; Tinidazole

1984
Primary tumor control after radiotherapy for carcinoma of the bronchus.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:4

    Topics: Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Double-Blind Method; Humans; Misonidazole; Neoplasm Metastasis; Nitroimidazoles; Radiation Tolerance

1984
The treatment of locally advanced head and neck cancer with misonidazole, hyperbaric oxygen and irradiation: an interim report.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Middle Aged; Misonidazole; Nitroimidazoles; Pilot Projects; Prospective Studies; Radiation-Sensitizing Agents; Random Allocation

1984
Hyperfractionated radiotherapy with or without misonidazole: results of a prospective randomized study in stage III-IV squamous cell carcinoma of the head and neck.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:10

    Topics: Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cobalt Radioisotopes; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Prospective Studies; Radiation-Sensitizing Agents; Radioisotope Teletherapy; Radiotherapy Dosage; Random Allocation

1984
A trial of Ro 03-8799 (pimonidazole) in carcinoma of the uterine cervix: an interim report from the Medical Research Council Working Party on advanced carcinoma of the cervix.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1993, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Aged; Blood Transfusion; Brachytherapy; Carcinoma, Squamous Cell; Diarrhea; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy Dosage; Remission Induction; Survival Rate; Uterine Cervical Neoplasms; Vomiting

1993
A clinical study of hypoxia and metallothionein protein expression in squamous cell carcinomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:3

    Topics: Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Metallothionein; Neoplasm Staging; Nitroimidazoles; Proliferating Cell Nuclear Antigen; Protein Precursors; Uterine Cervical Neoplasms

2000
Logistics in designing clinical trials for etanidazole (SR 2508): an RTOG experience.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Etanidazole; Head and Neck Neoplasms; Humans; Nitroimidazoles; Radiation-Sensitizing Agents; Research Design

1992
First analysis of tumor regression for the European randomized trial of etanidazole combined with radiotherapy in head and neck carcinomas.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Etanidazole; Female; Head and Neck Neoplasms; Humans; Male; Nitroimidazoles; Radiation-Sensitizing Agents

1992
Progress report of a phase II and a phase III trial with etanidazole (SR-2508): a multicentre European study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1991, Volume: 20 Suppl 1

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Evaluation; Etanidazole; Europe; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Radiation-Sensitizing Agents

1991
Clinical trials with etanidazole (SR-2508) by the Radiation Therapy Oncology Group (RTOG).
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1991, Volume: 20 Suppl 1

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Evaluation; Etanidazole; Head and Neck Neoplasms; Humans; Nitroimidazoles; Radiation-Sensitizing Agents

1991

Other Studies

98 other study(ies) available for azomycin and Carcinoma, Epidermoid

ArticleYear
Influence of FAZA PET hypoxia and HPV-status for the outcome of head and neck squamous cell carcinoma (HNSCC) treated with radiotherapy: Long-term results from the DAHANCA 24 trial (NCT01017224).
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2020, Volume: 151

    Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Head and Neck Neoplasms; Humans; Hypoxia; Neoplasm Recurrence, Local; Nitroimidazoles; Papillomavirus Infections; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck

2020
Noninvasive Imaging of Cycling Hypoxia in Head and Neck Cancer Using Intrinsic Susceptibility MRI.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2017, Aug-01, Volume: 23, Issue:15

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Contrast Media; Female; Head and Neck Neoplasms; Humans; Lymph Nodes; Magnetic Resonance Imaging; Male; Mice; Neovascularization, Pathologic; Nitroimidazoles; Radiation Tolerance; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Xenograft Model Antitumor Assays

2017
Correlation analysis of [
    Acta oncologica (Stockholm, Sweden), 2017, Volume: 56, Issue:9

    Topics: Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Middle Aged; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Prognosis; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Small Cell Lung Carcinoma

2017
Optical spectroscopic sensing of tumor hypoxia.
    Journal of biomedical optics, 2018, Volume: 23, Issue:6

    Topics: Animals; Biosensing Techniques; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Hemoglobins; Humans; Mice; Mice, Nude; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Spectrum Analysis; Tumor Cells, Cultured; Tumor Hypoxia

2018
PET imaging of tumor hypoxia using 18F-labeled pimonidazole.
    Acta oncologica (Stockholm, Sweden), 2013, Volume: 52, Issue:7

    Topics: Animals; Carcinoma, Squamous Cell; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Hypoxia; Mammary Neoplasms, Animal; Mice; Mice, Inbred C3H; Mice, Nude; Nitroimidazoles; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Tumor Cells, Cultured

2013
Hypoxia-inducible factor pathway inhibition resolves tumor hypoxia and improves local tumor control after single-dose irradiation.
    International journal of radiation oncology, biology, physics, 2014, Jan-01, Volume: 88, Issue:1

    Topics: Amines; Animals; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Nucleus; Dose Fractionation, Radiation; Electron Transport Complex I; Female; Heterografts; Humans; Hypoxia-Inducible Factor 1; Ki-67 Antigen; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Random Allocation; Tumor Microenvironment

2014
A prospective clinical study of ¹⁸F-FAZA PET-CT hypoxia imaging in head and neck squamous cell carcinoma before and during radiation therapy.
    European journal of nuclear medicine and molecular imaging, 2014, Volume: 41, Issue:8

    Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals

2014
Dynamics of tumor hypoxia assessed by 18F-FAZA PET/CT in head and neck and lung cancer patients during chemoradiation: possible implications for radiotherapy treatment planning strategies.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 113, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Hypoxia; Chemoradiotherapy; Cohort Studies; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Radiotherapy Planning, Computer-Assisted; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed

2014
The Effects of Pulsed Radiation Therapy on Tumor Oxygenation in 2 Murine Models of Head and Neck Squamous Cell Carcinoma.
    International journal of radiation oncology, biology, physics, 2015, Jul-15, Volume: 92, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Coloring Agents; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Heterografts; Mice; Mice, Nude; Misonidazole; Neoplasm Recurrence, Local; Nitroimidazoles; Oxygen Consumption; Positron-Emission Tomography; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck; Tumor Burden

2015
Assessment of hypoxic subvolumes in laryngeal cancer with (18)F-fluoroazomycinarabinoside ((18)F-FAZA)-PET/CT scanning and immunohistochemistry.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 117, Issue:1

    Topics: Aged; Aged, 80 and over; Biomarkers; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypoxia; Laryngeal Neoplasms; Laryngectomy; Male; Middle Aged; Multimodal Imaging; Neoplasm Recurrence, Local; Nitroimidazoles; Pilot Projects; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed

2015
Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs.
    Cancer research, 2015, Oct-01, Volume: 75, Issue:19

    Topics: Activation, Metabolic; Antineoplastic Agents; Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Chemoradiotherapy; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Head and Neck Neoplasms; High-Throughput Screening Assays; Humans; Neoplasm Proteins; Nitroimidazoles; Papillomaviridae; Papillomavirus Infections; Phosphoramide Mustards; Prodrugs; Retrospective Studies; RNA Interference; RNA, Messenger; RNA, Small Interfering; Tirapazamine; Triazines; Tumor Microenvironment; Tumor Stem Cell Assay

2015
Correlation of FMISO simulations with pimonidazole-stained tumor xenografts: A question of O2 consumption?
    Medical physics, 2016, Volume: 43, Issue:7

    Topics: Animals; Benzimidazoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Computer Simulation; Feasibility Studies; Fluorescent Antibody Technique; Head and Neck Neoplasms; Humans; Hypoxia; Mice, Nude; Misonidazole; Models, Biological; Neoplasm Transplantation; Nitroimidazoles; Oxygen Consumption; Platelet Endothelial Cell Adhesion Molecule-1; Tumor Microenvironment

2016
Resolution in PET hypoxia imaging: voxel size matters.
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:7

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Mice; Mice, Nude; Microscopy, Fluorescence; Necrosis; Neoplasms, Experimental; Nitroimidazoles; Positron-Emission Tomography

2008
Core needle biopsies for determination of the microenvironment in individual tumours for longitudinal radiobiological studies.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2009, Volume: 92, Issue:3

    Topics: Animals; Biopsy, Needle; Carcinoma, Squamous Cell; Confidence Intervals; Disease Models, Animal; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Environment; Female; Humans; Hypoxia; Immunohistochemistry; Longitudinal Studies; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Probability; Radiobiology; Random Allocation; Reference Values

2009
Hypoxia in larynx carcinomas assessed by pimonidazole binding and the value of CA-IX and vascularity as surrogate markers of hypoxia.
    European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Biomarkers; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Humans; Immunohistochemistry; Laryngeal Neoplasms; Male; Middle Aged; Nitroimidazoles; Radiation-Sensitizing Agents

2009
Can hypoxia-PET map hypoxic cell density heterogeneity accurately in an animal tumor model at a clinically obtainable image contrast?
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2009, Volume: 92, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Cell Count; Cell Hypoxia; Disease Models, Animal; Female; Hypoxia; Mice; Mice, Inbred C3H; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Radiopharmaceuticals; Random Allocation; Sensitivity and Specificity; Tissue Distribution

2009
Co-localisation of hypoxia and perfusion markers with parameters of glucose metabolism in human squamous cell carcinoma (hSCC) xenografts.
    International journal of radiation biology, 2009, Volume: 85, Issue:11

    Topics: Animals; Benzimidazoles; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Female; Fluorescent Dyes; Glucose; Humans; Hypoxia; Lactic Acid; Male; Mice; Mice, Nude; Microscopy, Fluorescence; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents; Transplantation, Heterologous

2009
Correlating quantitative MR measurements of standardized tumor lines with histological parameters and tumor control dose.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 96, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Disease Models, Animal; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Humans; Immunohistochemistry; Lactic Acid; Magnetic Resonance Imaging; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Oxygen Consumption; Radiation Dosage; Radiation-Sensitizing Agents; Sensitivity and Specificity; Transplantation, Heterologous

2010
Radiobiological hypoxia, histological parameters of tumour microenvironment and local tumour control after fractionated irradiation.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 96, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Cell Division; Cell Hypoxia; Confidence Intervals; Disease Models, Animal; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Radiobiology; Transplantation, Heterologous; Tumor Microenvironment

2010
Effect of cetuximab and fractionated irradiation on tumour micro-environment.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 97, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Carcinoma, Squamous Cell; Cell Line, Tumor; Cetuximab; Combined Modality Therapy; Dose Fractionation, Radiation; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Male; Mice; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents; Signal Transduction; Transplantation, Heterologous; Xenograft Model Antitumor Assays

2010
Assessing hypoxia in animal tumor models based on pharmocokinetic analysis of dynamic FAZA PET.
    Acta oncologica (Stockholm, Sweden), 2010, Volume: 49, Issue:7

    Topics: Animals; Carcinoma, Squamous Cell; Female; Gingival Neoplasms; Humans; Hypoxia; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Transplantation, Heterologous; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2010
Exploratory study of the prognostic value of microenvironmental parameters during fractionated irradiation in human squamous cell carcinoma xenografts.
    International journal of radiation oncology, biology, physics, 2011, Jul-15, Volume: 80, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Dose Fractionation, Radiation; Humans; Mice; Mice, Nude; Nitroimidazoles; Prognosis; Radiation-Sensitizing Agents; Tumor Microenvironment; Xenograft Model Antitumor Assays

2011
Perfusion estimated with rapid dynamic contrast-enhanced magnetic resonance imaging correlates inversely with vascular endothelial growth factor expression and pimonidazole staining in head-and-neck cancer: a pilot study.
    International journal of radiation oncology, biology, physics, 2011, Nov-15, Volume: 81, Issue:4

    Topics: Aged; Algorithms; Carcinoma, Squamous Cell; Cell Hypoxia; Coloring Agents; Contrast Media; Female; Head and Neck Neoplasms; Humans; Kinetics; Magnetic Resonance Imaging; Male; Middle Aged; Models, Biological; Neoplasm Proteins; Neovascularization, Pathologic; Nitroimidazoles; Pilot Projects; Real-Time Polymerase Chain Reaction; Tumor Burden; Vascular Endothelial Growth Factor A

2011
Measuring tumor hypoxia with ¹⁸F-FETNIM PET in esophageal squamous cell carcinoma: a pilot clinical study.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2012, Volume: 25, Issue:1

    Topics: Carcinoma, Squamous Cell; Chemoradiotherapy; Esophageal Neoplasms; Female; Fluorine Radioisotopes; Humans; Hypoxia; Logistic Models; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Oxygen; Pilot Projects; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; ROC Curve; Tomography, X-Ray Computed; Treatment Outcome

2012
Inhibition of tumor lactate oxidation: consequences for the tumor microenvironment.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011, Volume: 99, Issue:3

    Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cinnamates; Female; Fluorodeoxyglucose F18; Glucose; Glycolysis; Head and Neck Neoplasms; Immunoenzyme Techniques; Lactates; Linear Models; Luminescent Measurements; Mice; Mice, Nude; Monocarboxylic Acid Transporters; Nitroimidazoles; Oxidation-Reduction; Symporters; Tumor Microenvironment; Uterine Cervical Neoplasms

2011
Expression of EGFR under tumor hypoxia: identification of a subpopulation of tumor cells responsible for aggressiveness and treatment resistance.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Disease-Free Survival; ErbB Receptors; Head and Neck Neoplasms; Humans; Nitroimidazoles; Prognosis; Radiation Tolerance; Radiation-Sensitizing Agents

2012
Copper-64-diacetyl-bis(N(4)-methylthiosemicarbazone) pharmacokinetics in FaDu xenograft tumors and correlation with microscopic markers of hypoxia.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Animals; Autoradiography; Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Coordination Complexes; Head and Neck Neoplasms; Humans; Immunohistochemistry; Muscles; Nitroimidazoles; Organometallic Compounds; Partial Pressure; Radionuclide Imaging; Rats; Rats, Nude; Thiosemicarbazones; Tissue Distribution; Transplantation, Heterologous; Tumor Microenvironment; Xenograft Model Antitumor Assays

2012
Activation of AKT by hypoxia: a potential target for hypoxic tumors of the head and neck.
    BMC cancer, 2012, Oct-10, Volume: 12

    Topics: Animals; Blotting, Western; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; ErbB Receptors; Fluorescent Antibody Technique; Head and Neck Neoplasms; Heterocyclic Compounds, 3-Ring; Humans; Hypoxia; Mice; Mice, Inbred BALB C; Mice, Nude; Nitroimidazoles; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Radiation-Sensitizing Agents; Radiotherapy; Receptor, ErbB-2; Signal Transduction; Tumor Microenvironment; Xenograft Model Antitumor Assays

2012
Prognostic value of HIF-1α expression during fractionated irradiation.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2012, Volume: 188, Issue:11

    Topics: Animals; Biomarkers, Tumor; Blotting, Western; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Dose Fractionation, Radiation; Female; Gene Expression; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Otorhinolaryngologic Neoplasms; Prognosis; Radiation-Sensitizing Agents; Statistics as Topic; Transplantation, Heterologous

2012
HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors.
    International journal of radiation oncology, biology, physics, 2002, Dec-01, Volume: 54, Issue:5

    Topics: Carcinoma, Squamous Cell; Dimerization; Dose-Response Relationship, Drug; Head and Neck Neoplasms; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Idoxuridine; Immunohistochemistry; Ki-67 Antigen; Neovascularization, Pathologic; Nitroimidazoles; Nucleic Acid Synthesis Inhibitors; Perfusion; Transcription Factors; Treatment Outcome

2002
Orally administered pimonidazole to label hypoxic tumor cells.
    Cancer research, 2002, Dec-01, Volume: 62, Issue:23

    Topics: Administration, Oral; Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Flow Cytometry; Humans; Male; Mice; Mice, SCID; Neoplasm Transplantation; Nitroimidazoles; Transplantation, Heterologous; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2002
GLUT-1 and CAIX as intrinsic markers of hypoxia in carcinoma of the cervix: relationship to pimonidazole binding.
    International journal of cancer, 2003, Mar-10, Volume: 104, Issue:1

    Topics: Adult; Antigens, Neoplasm; Biomarkers; Biopsy; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; DNA-Binding Proteins; Energy Metabolism; Female; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Microelectrodes; Middle Aged; Monosaccharide Transport Proteins; Neoplasm Proteins; Nitroimidazoles; Nuclear Proteins; Observer Variation; Oxygen; Partial Pressure; Radiation-Sensitizing Agents; Reproducibility of Results; Transcription Factors; Uterine Cervical Neoplasms

2003
Hypoxia and differentiation in squamous cell carcinomas of the uterine cervix: pimonidazole and involucrin.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Oct-15, Volume: 9, Issue:13

    Topics: Biopsy; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line, Tumor; Female; Humans; Hypoxia; Immunohistochemistry; In Situ Hybridization; Metallothionein; Nitroimidazoles; Oxygen; Prognosis; Protein Precursors; Radiation-Sensitizing Agents; RNA, Messenger; Transcription, Genetic; Uterine Cervical Neoplasms

2003
Differentiation-associated staining with anti-pimonidazole antibodies in head and neck tumors.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2004, Volume: 70, Issue:1

    Topics: Antibodies, Anti-Idiotypic; Biomarkers; Carcinoma, Squamous Cell; Flow Cytometry; Frozen Sections; Head and Neck Neoplasms; Humans; Hypoxia; NAD(P)H Dehydrogenase (Quinone); NADPH-Ferrihemoprotein Reductase; Nitroimidazoles; Prognosis; Radiation-Sensitizing Agents; Staining and Labeling

2004
Quantifying transient hypoxia in human tumor xenografts by flow cytometry.
    Cancer research, 2004, Sep-01, Volume: 64, Issue:17

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Colonic Neoplasms; Female; Flow Cytometry; Humans; Mice; Mice, SCID; Nitroimidazoles; Oxygen; Partial Pressure; Transplantation, Heterologous; Uterine Cervical Neoplasms

2004
TX-1877, a bifunctional hypoxic cell radiosensitizer, enhances anticancer host response: immune cell migration and nitric oxide production.
    International journal of cancer, 2005, Sep-10, Volume: 116, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Hypoxia; Cell Movement; Dendritic Cells; Disease Models, Animal; Humans; Mice; Nitric Oxide; Nitroimidazoles; Radiation Tolerance; T-Lymphocytes, Cytotoxic

2005
Does heterogeneity of pimonidazole labelling correspond to the heterogeneity of radiation-response of FaDu human squamous cell carcinoma?
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2005, Volume: 76, Issue:2

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Dose-Response Relationship, Radiation; Female; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Radiation Tolerance

2005
Erythropoietin receptor is not a surrogate marker for tumor hypoxia and does not correlate with survival in head and neck squamous cell carcinomas.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2005, Volume: 76, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Male; Middle Aged; Nitroimidazoles; Receptors, Erythropoietin; Survival Rate

2005
Reevaluation of the radiosensitizing effects of sanazole and nimorazole in vitro and in vivo.
    Journal of radiation research, 2005, Volume: 46, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Evaluation, Preclinical; Female; Mice; Nimorazole; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Treatment Outcome; Triazoles

2005
Evaluation of hypoxia-specific cytotoxic bioreductive agent-sodium borocaptate-10B conjugates as 10B-carriers in boron neutron capture therapy.
    Radiation medicine, 2006, Volume: 24, Issue:2

    Topics: Animals; Borohydrides; Boron; Boron Neutron Capture Therapy; Carcinoma, Squamous Cell; Fluorescent Antibody Technique, Indirect; Isotopes; Mice; Molecular Structure; Nitriles; Nitroimidazoles; Quinoxalines; Sulfhydryl Compounds; Tissue Distribution

2006
Imaging hypoxia after oxygenation-modification: comparing [18F]FMISO autoradiography with pimonidazole immunohistochemistry in human xenograft tumors.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 80, Issue:2

    Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Fluorine Radioisotopes; Glioblastoma; Head and Neck Neoplasms; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Radionuclide Imaging

2006
Microsatellite alterations in head and neck squamous cell carcinoma and relation to expression of pimonidazole, CA IX and GLUT-1.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 80, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Base Sequence; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Excitatory Amino Acid Transporter 2; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Loss of Heterozygosity; Male; Microsatellite Instability; Middle Aged; Molecular Sequence Data; Nitroimidazoles

2006
Pimonidazole labelling and response to fractionated irradiation of five human squamous cell carcinoma (hSCC) lines in nude mice: the need for a multivariate approach in biomarker studies.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 81, Issue:2

    Topics: Animals; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Dose Fractionation, Radiation; Female; Humans; Imaging, Three-Dimensional; Male; Mice; Mice, Nude; Nitroimidazoles; Prognosis; Treatment Outcome; Xenograft Model Antitumor Assays

2006
Tumour cell proliferation under hypoxic conditions in human head and neck squamous cell carcinomas.
    Oral oncology, 2008, Volume: 44, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Biopsy; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Proliferation; Female; Head and Neck Neoplasms; Humans; Idoxuridine; Image Processing, Computer-Assisted; Male; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Nitroimidazoles; Nucleic Acid Synthesis Inhibitors; Radiation-Sensitizing Agents; Treatment Outcome

2008
Identifying and targeting hypoxia in head and neck cancer: a brief overview of current approaches.
    International journal of radiation oncology, biology, physics, 2007, Volume: 69, Issue:2 Suppl

    Topics: Antigens, Neoplasm; Biomarkers; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Electrodes; Etanidazole; Head and Neck Neoplasms; Humans; Hydrocarbons, Fluorinated; Intracellular Signaling Peptides and Proteins; Mitochondrial Proteins; Neoplasm Proteins; Nitroimidazoles; Osteopontin; Oxygen; Partial Pressure; Radiation-Sensitizing Agents; Tirapazamine; Triazines

2007
Hypoxia imaging with FAZA-PET and theoretical considerations with regard to dose painting for individualization of radiotherapy in patients with head and neck cancer.
    International journal of radiation oncology, biology, physics, 2007, Oct-01, Volume: 69, Issue:2

    Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Feasibility Studies; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Positron-Emission Tomography; Radiotherapy, Intensity-Modulated; Tomography, X-Ray Computed

2007
Imaging hypoxia in xenografted and murine tumors with 18F-fluoroazomycin arabinoside: a comparative study involving microPET, autoradiography, PO2-polarography, and fluorescence microscopy.
    International journal of radiation oncology, biology, physics, 2008, Mar-15, Volume: 70, Issue:4

    Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Fibrosarcoma; Fluorine Radioisotopes; Immunocompromised Host; Immunohistochemistry; Mice; Mice, Inbred C3H; Mice, Nude; Microscopy, Fluorescence; Nitroimidazoles; Oxygen; Polarography; Positron-Emission Tomography; Radiation-Sensitizing Agents; Transplantation, Heterologous

2008
Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome: in regard to Evans et al. (Int J Radiat Oncol Biol Phys 2007;69:1024-1031).
    International journal of radiation oncology, biology, physics, 2008, Apr-01, Volume: 70, Issue:5

    Topics: Carbon Dioxide; Carcinoma, Squamous Cell; Cell Hypoxia; Head and Neck Neoplasms; Humans; Nitroimidazoles; Oxygen; Prognosis; Radiation-Sensitizing Agents; Time Factors

2008
Reduced fractionation and the potential of hypoxic cell sensitizers in irradiation of malignant epithelial tumors.
    International journal of radiation oncology, biology, physics, 1980, Volume: 6, Issue:1

    Topics: Adenocarcinoma; Carcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Misonidazole; Mouth Neoplasms; Nitroimidazoles; Oropharynx; Pharyngeal Neoplasms; Radiation-Sensitizing Agents; Radiotherapy Dosage; Retrospective Studies

1980
[Biological studies of proton irradiation under combination with a hypoxic cell sensitizer].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1982, Apr-25, Volume: 42, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Female; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Protons; Radiotherapy, High-Energy; Skin Neoplasms

1982
The use of misonidazole in association with a three-fractions per day regimen in advanced head and neck epidermoid cancer. A pilot study.
    American journal of clinical oncology, 1983, Volume: 6, Issue:1

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Erythema; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Pilot Projects; Radiotherapy Dosage

1983
Interstitial misonidazole. A preliminary report on a new perspective in clinical radiation sensitization and hypoxic cell chemotherapy.
    Cancer, 1984, Oct-15, Volume: 54, Issue:8

    Topics: Aged; Carcinoma, Squamous Cell; Female; Humans; Injections; Male; Melanoma; Middle Aged; Misonidazole; Nitroimidazoles; Skin Neoplasms

1984
The topical use of misonidazole in bladder cancer.
    Progress in clinical and biological research, 1983, Volume: 132D

    Topics: Administration, Oral; Administration, Topical; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Humans; Kinetics; Misonidazole; Mucous Membrane; Nitroimidazoles; Urinary Bladder; Urinary Bladder Neoplasms

1983
[Experimental studies on radiosensitization of hypoxic cancer cells].
    Nihon Sanka Fujinka Gakkai zasshi, 1983, Volume: 35, Issue:11

    Topics: Animals; Carcinoma, Squamous Cell; Female; Humans; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Oxygen; Uterine Cervical Neoplasms

1983
[Flow-microfluorometric studies on the effect of misonidazole as a radiosensitizer for human uterine cervical carcinoma transplanted to nude mice].
    Nihon Sanka Fujinka Gakkai zasshi, 1983, Volume: 35, Issue:12

    Topics: Animals; Carcinoma, Squamous Cell; DNA, Neoplasm; Female; Flow Cytometry; Humans; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Uterine Cervical Neoplasms

1983
[Effect of even or uneven dose fractionation regime on murine squamous cell carcinoma with combined use of misonidazole].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1983, Oct-25, Volume: 43, Issue:10

    Topics: Animals; Carcinoma, Squamous Cell; Combined Modality Therapy; Fibrosarcoma; Mice; Mice, Inbred Strains; Misonidazole; Nitroimidazoles; Radiotherapy Dosage

1983
Fatal misonidazole-induced encephalopathy: an RTOG case report.
    Cancer, 1982, Feb-01, Volume: 49, Issue:3

    Topics: Brain Diseases; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Humans; Middle Aged; Misonidazole; Nitroimidazoles; Palatal Neoplasms; Tongue Neoplasms

1982
Large fraction radiotherapy plus misonidazole for treatment of advanced lung cancer: report of a phase I/II trial.
    International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Nitroimidazoles; Radiotherapy; Radiotherapy Dosage

1982
Misonidazole Neuropathy: a clinical, electrophysiological, and histological study.
    Annals of neurology, 1982, Volume: 12, Issue:1

    Topics: Aged; Carcinoma, Squamous Cell; Electromyography; Female; Humans; Laryngeal Neoplasms; Lung Neoplasms; Male; Median Nerve; Middle Aged; Misonidazole; Nerve Fibers, Myelinated; Nervous System Diseases; Neural Conduction; Neuromuscular Diseases; Nitroimidazoles; Paresthesia; Peroneal Nerve; Pharyngeal Neoplasms; Sensation; Sural Nerve; Tibial Nerve

1982
The feasibility of high-dose multiple daily fractionation and its combination with anoxic cell sensitizers in the treatment of head and neck cancer. A pilot study of the Radiotherapy Group of the EORTC (European Organisation for Research on Treatment of C
    International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:10

    Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Pilot Projects; Prognosis; Radiotherapy Dosage

1982
Effects of misonidazole on tumor cell radiation sensitivity and potentially lethal damage repair in vivo and in vitro.
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:7

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation Tolerance; Time Factors

1981
Pilot study of radiotherapy with misonidazole in head and neck cancer.
    Clinical radiology, 1981, Volume: 32, Issue:2

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nervous System Diseases; Nitroimidazoles; Pilot Projects; Radiotherapy Dosage

1981
Comparison of hyperbaric oxygen and misonidazole in fractionated irradiation of murine tumors.
    Radiation research, 1981, Volume: 87, Issue:2

    Topics: Animals; Carcinoma, Squamous Cell; Female; Hyperbaric Oxygenation; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Skin

1981
Phenytoin-induced changes in the pharmacokinetics of misonidazole in radiotherapy patients.
    British journal of cancer, 1981, Volume: 44, Issue:4

    Topics: Carcinoma, Squamous Cell; Esophageal Neoplasms; Half-Life; Head and Neck Neoplasms; Humans; Kinetics; Misonidazole; Nitroimidazoles; Phenytoin; Time Factors

1981
The value of adjuvant misonidazole in the definitive irradiation of advanced head and neck squamous cancer: an RTOG pilot study (#78-02).
    International journal of radiation oncology, biology, physics, 1981, Volume: 7, Issue:12

    Topics: Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Nausea; Neoplasm Recurrence, Local; Neoplasm Staging; Nitroimidazoles; Paresthesia; Pharyngeal Neoplasms; Prognosis

1981
Optical isomers of a new 2-nitroimidazole nucleoside analog (PR-350 series): radiosensitization efficiency and toxicity.
    International journal of radiation oncology, biology, physics, 1995, Aug-30, Volume: 33, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Female; Mice; Mice, Inbred C3H; Nitroimidazoles; Nucleosides; Radiation Dosage; Radiation-Sensitizing Agents; Stereoisomerism; Tumor Stem Cell Assay

1995
[Radiosensitizing effects of nitroimidazole derivative, KIN-804].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1995, Volume: 55, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Hydroxamic Acids; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Skin Neoplasms

1995
DNA-targeted 2-nitroimidazoles: in vitro and in vivo studies.
    British journal of cancer, 1994, Volume: 70, Issue:6

    Topics: Animals; Carcinoma, Squamous Cell; Cell Division; CHO Cells; Cricetinae; Cytotoxins; DNA; In Vitro Techniques; Intercalating Agents; Mice; Mice, Inbred C3H; Nitroimidazoles; Organoids; Phenanthridines; Radiation-Sensitizing Agents; Solubility; Structure-Activity Relationship; Tumor Cells, Cultured

1994
Reoxygenation in the SCCVII tumor after KU-2285 sensitization plus single or fractionated irradiation.
    International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Mice; Mice, Inbred C3H; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents

1994
Comparison of radiosensitizing effect of KU-2285 and SR-2508 at low drug concentrations and doses.
    International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Cell Survival; Dose-Response Relationship, Drug; Etanidazole; Female; Mice; Mice, Inbred C3H; Micronucleus Tests; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents

1994
Radiosensitizing activity and pharmacokinetics of multiple dose administered KU-2285 in peripheral nerve tissue in mice.
    International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Etanidazole; Female; Male; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Misonidazole; Nitroimidazoles; Peripheral Nerves; Radiation-Sensitizing Agents

1994
KIN-804 vs. KU-2285 as a radiosensitizer for clinical use.
    International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Chromosome Aberrations; Female; Humans; Hydroxamic Acids; Mice; Mice, Inbred C3H; Micronucleus Tests; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents

1994
In vivo radiosensitizing effect of nitroimidazole derivative KIN-804.
    International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Hydroxamic Acids; Lethal Dose 50; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents

1994
Imaging tumor hypoxia and tumor perfusion.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1993, Volume: 34, Issue:6

    Topics: Brain Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Glioblastoma; Head and Neck Neoplasms; Humans; Iodine Radioisotopes; Lung Neoplasms; Male; Nitroimidazoles; Organotechnetium Compounds; Oximes; Sarcoma; Soft Tissue Neoplasms; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon

1993
Comparison of in vivo efficacy of hypoxic cytotoxin tirapazamine and hypoxic cell radiosensitizer KU-2285 in combination with single and fractionated irradiation.
    Japanese journal of cancer research : Gann, 1996, Volume: 87, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Radiotherapy Dosage; Tirapazamine; Triazines

1996
Uptake and retention of nitroimidazole-carboranes designed for boron neutron capture therapy in experimental murine tumours: detection by 11B magnetic resonance spectroscopy.
    International journal of radiation biology, 1996, Volume: 70, Issue:5

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Carcinoma, Squamous Cell; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Nitroimidazoles; Sarcoma, Experimental

1996
The radiosensitizing effects of hypoxic cell sensitizer on SCCVII tumors in mice evaluated by highly accurate colony formation assay assisted by microcomputer.
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1996, Volume: 56, Issue:14

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Etanidazole; Male; Mice; Mice, Inbred C3H; Microcomputers; Misonidazole; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Tumor Stem Cell Assay

1996
A comparison of the physiological effects of RSU1069 and RB6145 in the SCCVII murine tumour.
    Acta oncologica (Stockholm, Sweden), 1996, Volume: 35, Issue:8

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Disease Models, Animal; Female; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C3H; Misonidazole; Neovascularization, Pathologic; Nitroimidazoles; Oxygen; Phosphorus Radioisotopes

1996
Proliferation and hypoxia in human squamous cell carcinoma of the cervix: first report of combined immunohistochemical assays.
    International journal of radiation oncology, biology, physics, 1997, Mar-01, Volume: 37, Issue:4

    Topics: Adult; Antigens, Nuclear; Biomarkers; Carcinoma, Squamous Cell; Cell Division; Cell Hypoxia; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Nitroimidazoles; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms

1997
Higher incidence of malignant neoplasms after heart transplantation for treatment of chronic Chagas' heart disease.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1998, Volume: 17, Issue:4

    Topics: Adult; Carcinoma, Squamous Cell; Chagas Cardiomyopathy; Chemoprevention; Chronic Disease; Cocarcinogenesis; Cyclosporine; Female; Follow-Up Studies; Heart Failure; Heart Transplantation; Humans; Immunosuppressive Agents; Incidence; Lung Diseases; Lymphoproliferative Disorders; Male; Mutagens; Neoplasms; Neurilemmoma; Nitroimidazoles; Recurrence; Sarcoma, Kaposi; Skin Neoplasms; Survival Rate; Trypanocidal Agents

1998
Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker.
    Cancer research, 1998, Sep-01, Volume: 58, Issue:17

    Topics: Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Endothelial Growth Factors; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Lymphokines; Nitroimidazoles; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1998
Vascular architecture and microenvironmental parameters in human squamous cell carcinoma xenografts: effects of carbogen and nicotinamide.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1999, Volume: 50, Issue:2

    Topics: Animals; Benzimidazoles; Blood Vessels; Carbon Dioxide; Carcinoma, Squamous Cell; Cell Division; Endothelium, Vascular; Humans; Hypoxia; Laryngeal Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Niacinamide; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Theophylline; Transplantation, Heterologous; Tumor Cells, Cultured

1999
Diffusion limited hypoxia estimated by vascular image analysis: comparison with pimonidazole staining in human tumors.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2000, Volume: 55, Issue:3

    Topics: Adenocarcinoma; Blood Vessels; Carcinoma, Squamous Cell; Cell Hypoxia; Diffusion; Esophageal Neoplasms; Female; Humans; Image Processing, Computer-Assisted; Nitroimidazoles; Observer Variation; Radiation-Sensitizing Agents; Rectal Neoplasms; Reproducibility of Results; Uterine Cervical Neoplasms

2000
Vascular architecture and hypoxic profiles in human head and neck squamous cell carcinomas.
    British journal of cancer, 2000, Volume: 83, Issue:5

    Topics: Aged; Biomarkers; Biopsy; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Hypoxia; Image Processing, Computer-Assisted; Immunohistochemistry; Laryngeal Neoplasms; Male; Microscopy, Fluorescence; Middle Aged; Nitroimidazoles; Oropharyngeal Neoplasms; Prognosis

2000
Comparison between the comet assay and pimonidazole binding for measuring tumour hypoxia.
    British journal of cancer, 2000, Volume: 83, Issue:11

    Topics: Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; Cell Hypoxia; Comet Assay; Cricetinae; Cricetulus; DNA, Neoplasm; Female; Flow Cytometry; Fluorescein-5-isothiocyanate; Humans; Immunoconjugates; Male; Mice; Mice, Inbred C3H; Mice, Inbred NOD; Mice, SCID; Nitroimidazoles; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2000
Changes in tumor hypoxia measured with a double hypoxic marker technique.
    International journal of radiation oncology, biology, physics, 2000, Dec-01, Volume: 48, Issue:5

    Topics: Animals; Benzimidazoles; Biomarkers; Carbon Dioxide; Carcinoma, Squamous Cell; Cell Hypoxia; Endothelium, Vascular; Fluorescent Dyes; Mice; Mice, Inbred BALB C; Mice, Nude; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Tumor Cells, Cultured

2000
Semiquantitative immunohistochemical analysis for hypoxia in human tumors.
    International journal of radiation oncology, biology, physics, 2001, Feb-01, Volume: 49, Issue:2

    Topics: Calibration; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Nitroimidazoles; Observer Variation; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms

2001
Local hypoxia is produced at sites of intratumour injection.
    British journal of cancer, 2002, Feb-01, Volume: 86, Issue:3

    Topics: Animals; Benzimidazoles; Carcinoma, Squamous Cell; Cell Hypoxia; Comet Assay; DNA Damage; Humans; Injections; Mice; Nitroimidazoles; Radiation-Sensitizing Agents

2002
[The use of potentiating agents in megavoltage therapy of non-resected localized carcinoma of the lung (author's transl)].
    Revue francaise des maladies respiratoires, 1979, Volume: 7, Issue:7

    Topics: Carcinoma, Squamous Cell; Dose-Response Relationship, Radiation; Hot Temperature; Humans; Lung Neoplasms; Neutrons; Nitroimidazoles; Radiotherapy, High-Energy

1979
The penetration of misonidazole into spontaneous canine tumours.
    British journal of cancer, 1979, Volume: 40, Issue:2

    Topics: Adenocarcinoma; Anesthesia, Intravenous; Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Dog Diseases; Dogs; Female; Fibrosarcoma; Half-Life; Lymphoma, Non-Hodgkin; Male; Mammary Glands, Animal; Meningioma; Misonidazole; Neoplasms; Nitroimidazoles; Osteosarcoma; Pentobarbital

1979
Response of the solid Guerin epitheliomas of rats to fractionated irradiation and a new 4-nitroimidazole.
    British journal of cancer, 1979, Volume: 40, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Male; Metronidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Rats; Rats, Inbred Strains; Time Factors; Transplantation, Homologous

1979
Radiosensitizing and cytocidal effects on hypoxic cells of RO-07-0582, and repair of x-ray injury, in an experimental mouse tumour.
    British journal of cancer, 1977, Volume: 35, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Hypoxia; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Skin Neoplasms; Transplantation, Homologous

1977
Technique, pharmacokinetics, toxicity, and efficacy of intratumoral etanidazole and radiotherapy for treatment of spontaneous feline oral squamous cell carcinoma.
    International journal of radiation oncology, biology, physics, 1991, Volume: 20, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Cat Diseases; Cats; Combined Modality Therapy; Etanidazole; Mouth Neoplasms; Necrosis; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy; Radiotherapy Dosage

1991
In vivo radiosensitizing activity of a new fluorinated hypoxic cell radiosensitizer, KU-2285, in combination with radiation dose fractionation.
    International journal of radiation oncology, biology, physics, 1991, Volume: 21, Issue:5

    Topics: Animals; Carcinoma, Squamous Cell; Cell Survival; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy Dosage

1991
Lack of stereoselectivity in the pharmacokinetics and metabolism of the radiosensitizer Ro 03-8799 in man.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:2

    Topics: Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nitroimidazoles; Radiation-Sensitizing Agents; Stereoisomerism

1991
[New results with delayed progression in the cell cycle of solid squamous cell carcinomas of the head-neck area after single and fractionated irradiation with cobalt-60 and neutrons].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1990, Volume: 166, Issue:11

    Topics: Animals; Carcinoma, Squamous Cell; Cell Cycle; Cobalt Radioisotopes; Head and Neck Neoplasms; Neoplasm Transplantation; Neutrons; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors; Transplantation, Heterologous

1990
Pharmacokinetics of etanidazole (SR-2508) in bladder and cervical cancer: evidence of diffusion from urine.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4

    Topics: Carcinoma, Squamous Cell; Diffusion; Etanidazole; Female; Humans; Nitroimidazoles; Radiation-Sensitizing Agents; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms

1989
A comparison of the tumour concentrations obtainable with misonidazole and Ro 03-8799.
    The British journal of radiology, 1986, Volume: 59, Issue:705

    Topics: Adult; Aged; Animals; Carcinoma, Squamous Cell; Cricetinae; Cricetulus; Female; Humans; Male; Melanoma; Mice; Middle Aged; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms

1986