azomycin has been researched along with Carcinoma, Epidermoid in 124 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 30 (24.19) | 18.7374 |
1990's | 26 (20.97) | 18.2507 |
2000's | 37 (29.84) | 29.6817 |
2010's | 30 (24.19) | 24.3611 |
2020's | 1 (0.81) | 2.80 |
Authors | Studies |
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Hansen, CR; Johansen, J; Kallehauge, J; Mortensen, LS; Overgaard, J; Primdahl, H; Saksø, M | 1 |
Baker, LCJ; Bhide, SA; Box, C; d'Arcy, JA; Dunlop, A; Eccles, SA; Harrington, KJ; Hopkinson, G; Koh, DM; Leach, MO; Mcquaid, D; Newbold, KL; Nutting, CM; Panek, R; Richardson, C; Riddell, AM; Robinson, SP; Schmidt, MA; Welsh, L; Wong, KH | 1 |
Bol, A; Di Perri, D; Geets, X; Hanin, FX; Janssens, G; Labar, D; Lee, JA; Robert, A; Sterpin, E | 1 |
Dadgar, S; Rajaram, N; Troncoso, JR | 1 |
Busk, M; Horsman, MR; Iversen, AB; Jakobsen, S; Ji, X; Lee, DY; Mortensen, LS; Nordsmark, M; Overgaard, J; Raleigh, JR | 1 |
Baumann, M; Brüchner, K; Gurtner, K; Helbig, L; Hess-Stumpp, H; Koi, L; Pruschy, M; Unterschemmann, K; Yaromina, A; Zips, D | 1 |
Bol, A; Differding, S; Grégoire, V; Hanin, FX; Labar, D; Lee, JA; Servagi-Vernat, S | 1 |
Giraud, P; Servagi-Vernat, S | 1 |
Bollineni, VR; Brouwer, CL; Groen, HJ; Halmos, GB; Koole, MJ; Langendijk, JA; Oosting, SF; Pruim, J; Steenbakkers, RJ; Vlasman, R; Widder, J; Wiegman, EM | 1 |
Bol, A; Differding, S; Grégoire, V; Hanin, FX; Labar, D; Lee, JA; Servagi-Vernat, S; Sterpin, E | 1 |
Galoforo, S; Grills, IS; Kane, JL; Krueger, SA; Marples, B; Wilson, GD; Wobb, J | 1 |
Bollineni, VR; Bruine de Bruin, L; de Bock, GH; Halmos, GB; Langendijk, JA; Pruim, J; Schuuring, E; Slagter-Menkema, L; Steenbakkers, RJ; van der Laan, BF; van der Wal, JE; van Hemel, BM; Wachters, JE | 1 |
Brown, KR; Goldstein, DP; Gu, Y; Hunter, FW; Joshi, N; Ketela, T; Koritzinsky, M; Moffat, J; Rischin, D; Shalev, Z; Solomon, B; Sreebhavan, S; Vellanki, RN; Wang, J; Weinreb, I; Wilson, WR; Wouters, BG; Young, RJ | 1 |
Fujibayashi, Y; Harada, R; Inubushi, M; Koizumi, M; Obata, T; Saga, T; Tanimoto, K; Uno, T; Yoshikawa, K; Zhang, MR | 1 |
Baumann, M; Mönnich, D; Thorwarth, D; Wack, LJ; Yaromina, A; Zips, D | 1 |
Busk, M; Horsman, MR; Overgaard, J | 1 |
Abrams, DN; Kumar, P; McEwan, AJ; Postema, EJ; Riauka, TA; Richmond, DA; Wiebe, LI | 1 |
Baumann, M; Eckardt, A; Eicheler, W; Schuetze, C; Thames, H; Yaromina, A; Zips, D | 1 |
Hoogsteen, IJ; Kaanders, JH; Lok, J; Marres, HA; Rijken, PF; Takes, RP; van der Kogel, AJ | 1 |
Busk, M; Bussink, J; Hansen, KV; Horsman, MR; Jakobsen, S; Overgaard, J; van der Kogel, A | 1 |
Baumann, M; Meyer, S; Mueller-Klieser, W; Quennet, V; Shakirin, G; Walenta, S; Yaromina, A; Zips, D | 1 |
Baumann, M; Flentje, M; Jakob, PM; Melkus, G; Mörchel, P; Yaromina, A; Zips, D | 1 |
Baumann, M; Dörfler, A; Eicheler, W; Hering, S; Leichtner, T; Thames, H; Yaromina, A; Zhou, X; Zips, D | 1 |
Baumann, M; Beuthien-Baumann, B; Bussink, J; Eicheler, W; Krause, M; Rijken, P; Santiago, A; van der Kogel, AJ; Yaromina, A | 1 |
Bachtiary, B; Dimopoulos, J; Dudczak, R; Georg, D; Karanikas, G; Kletter, K; Kommata, S; Lukic, D; Pötter, R; Schmid, MP; Schuetz, M | 1 |
Busk, M; Horsman, MR; Jakobsen, S; Munk, OL; Overgaard, J; Skals, M; Steiniche, T; Wang, T | 1 |
Baumann, M; Boeke, S; Kroeber, T; Meinzer, A; Thames, H; Yaromina, A; Zips, D | 1 |
Betts, G; Bonington, SC; Buckley, DL; Donaldson, SB; Homer, JJ; Kershaw, LE; Slevin, NJ; Valentine, H; West, CM | 1 |
Cabrera, AR; Fu, Z; Ma, L; Sun, X; Xie, P; Yang, Y; Yu, J; Yue, J; Zhao, S; Zheng, J | 1 |
Busk, M; Horsman, MR; Jakobsen, S; Mueller-Klieser, W; Overgaard, J; Steiniche, T; Walenta, S | 1 |
Bezak, E; Filip, SM; Marcu, LG | 1 |
Bussink, J; Hoogsteen, IJ; Kaanders, JH; Lok, J; Marres, HA; Rijken, PF; van den Hoogen, FJ | 1 |
Bartlett, R; Carlin, S; Humm, JL; McCall, KC; Reese, M | 1 |
Bussink, J; Grénman, R; Iida, M; Kaanders, JH; Span, PN; Stegeman, H; van der Kogel, AJ; Verheijen, MM; Waaijer, SJ; Wheeler, DL | 1 |
Baumann, M; Böke, S; Helbig, L; Koi, L; Sriramareddy, SN; Thames, HD; Yaromina, A; Zips, D | 1 |
Alsner, J; Busk, M; Jakobsen, S; Johansen, J; Kallehauge, J; Lassen, P; Mortensen, LS; Nordsmark, M; Overgaard, J; Petersen, H; Petersen, J; Primdahl, H; Sørensen, BS; Theil, J; Toustrup, K | 1 |
Dierckx, RA; Halmos, GB; Langedijk, JA; Pruim, J; Roodenburg, JL; van der Laan, BF; Wedman, J | 1 |
Balm, AJ; Begg, AC; Blijweert, E; Blommestijn, G; Delaere, P; Haustermans, KM; Hoebers, FJ; Hofland, I; Janssen, HL; Raleigh, JA; Sciot, R; Semenza, GL; Sprong, D; van Velthuysen, ML; Varia, MA | 1 |
Bennewith, KL; Durand, RE; Raleigh, JA | 1 |
Bussink, J; de Wilde, PC; Kaanders, JH; Ljungkvist, AS; Marres, HA; Pop, LA; Raleigh, JA; van den Hoogen, FJ; van der Kogel, AJ; Wijffels, KI | 1 |
Eskola, O; Grönroos, T; Lehtiö, K; Minn, H; Nyman, S; Oikonen, V; Roivainen, A | 1 |
Airley, RE; Davidson, SE; Harris, AL; Hunter, RD; Loncaster, J; Raleigh, JA; Stratford, IJ; West, CM | 1 |
Bussink, J; Kaanders, JH; van der Kogel, AJ | 2 |
Azuma, Y; Chou, SC; Lininger, RA; Murphy, BJ; Raleigh, JA; Varia, MA | 1 |
Balm, AJ; Begg, AC; Goethals, L; Haustermans, KM; Hoebers, FJ; Janssen, HL; Sprong, D; Stratford, IJ; Williams, KJ | 1 |
Bennewith, KL; Durand, RE | 1 |
Ahmed, SU; Furuichi, S; Hori, H; Kan, S; Kasai, S; Nagasawa, H; Okamoto, M; Oshikawa, T; Sasai, A; Sato, M; Tano, T; Uto, Y | 1 |
Baumann, M; Eicheler, W; Hessel, F; Hölscher, T; Krause, M; Petersen, C; Rosner, A; Thames, HD; Yaromina, A; Zips, D | 1 |
Hoogsteen, IJ; Kaanders, JH; Marres, HA; Peeters, WJ; Rijken, PF; van den Hoogen, FJ; van der Kogel, AJ | 1 |
Hori, H; Ito, M; Nagasawa, H; Ogino, H; Shibamoto, Y; Sugie, C; Suzuki, H; Uto, Y | 1 |
Gotoh, K; Hori, H; Kinashi, Y; Maruhashi, A; Masunaga, S; Nagasawa, H; Nagata, K; Ono, K; Sakurai, Y; Suzuki, M; Uto, Y | 1 |
Boerman, OC; Bussink, J; Kaanders, JH; Laverman, P; Lok, J; Oyen, WJ; Philippens, M; Troost, EG; van der Kogel, AJ | 1 |
Balm, A; Barbé, B; Begg, AC; De Schutter, H; Gregoire, V; Haustermans, K; Mahy, P; Nuyts, S; Spaepen, M; Vander Poorten, V | 1 |
Aquino-Parsons, C; Durand, RE | 1 |
Baumann, M; Eicheler, W; Haase, M; Krause, M; Mueller-Klieser, W; Petersen, C; Quennet, V; Raleigh, JA; Rosner, A; Thames, HD; Walenta, S; Yaromina, A; Zips, D | 1 |
Kaanders, JH; Marres, HA; Peters, JP; Rijken, PF; van der Kogel, AJ; Wijffels, KI | 1 |
Le, QT | 1 |
Dobritz, M; Grosu, AL; Jacob, V; Machulla, HJ; Molls, M; Piert, M; Reischl, G; Röper, B; Schwaiger, M; Souvatzoglou, M; Wester, HJ; Wiedenmann, N | 1 |
Busk, M; Bussink, J; Horsman, MR; Jakobsen, S; Keiding, S; Overgaard, J; van der Kogel, AJ | 1 |
Christian, N; De Bast, M; Geets, X; Gillart, J; Grégoire, V; Labar, D; Lee, J; Levêque, P; Lonneux, M; Mahy, P | 1 |
Byhardt, RW; Cox, JD; Greenberg, M; Komaki, R | 1 |
Ando, K; Furukawa, S; Hiraoka, T; Kanai, T; Kawachi, K; Koike, S; Majima, H | 1 |
Awwad, HK; Barsoum, M; El Badawy, S; El Baki, HA; El Merzabani, M; Ezzat, S; Omar, S; Zaki, A | 1 |
Hansen, HH; Kjaer, M; Panduro, J; Wolff-Jensen, J | 1 |
McGregor, IA; Sleigh, JD; Sweeney, G; Watson, JD | 1 |
Anderson, PJ; Bennett, MH; Dische, S; Saunders, MI | 1 |
Cridland, S; Sealy, R | 1 |
Demange, L; Froissart, D; Nguyen, TD; Panis, X | 1 |
Blekkenhorst, G; Cridland, S; Korrubel, J; Sealy, R | 1 |
Abd El Baki, H; Abd El Moneim, H; Awwad, HK; El Merzabani, M; Farag, HI; Omar, S | 1 |
Omura, M | 1 |
Kishino, Y | 1 |
Okada, S; Sakamoto, K; Takada, C; Takahashi, M; Yasunaga, T | 1 |
Ho, KC; Kun, LE; Moulder, JE | 1 |
Carella, RJ; Concannon, JP; Perez, CA; Phillips, TL; Simpson, JR | 1 |
Hansen, HS; Kamieniecka, Z; Melgaard, B; Paulson, OB; Pedersen, AG; Tang, X; Trojaborg, W | 1 |
Arcangeli, G; Chaplain, G; Gonzalez, D; Horiot, JC; Svoboda, V; Van den Bogaert, W; van der Schueren, E | 1 |
Aritake, S; Sakamoto, K | 1 |
Dawes, PJ; Henk, JM; Moore, JL; Paterson, IC | 1 |
Maimonis, P; Michaels, HB; Sedlacek, R; Suit, HD | 1 |
Moore, JL; Newman, H; Paterson, IC; Venables, S | 1 |
Fazekas, JT; Goodman, RL; McLean, CJ | 1 |
Abe, M; Iwai, H; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T; Suzuki, T; Takagi, T | 1 |
Tada, T | 1 |
Cowan, DS; Matejovic, JF; McClelland, RA; Rauth, AM | 1 |
Abe, M; Kitakabu, Y; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T; Takahashi, M | 1 |
Abe, M; Ishigaki, T; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T | 1 |
Abe, M; Iwai, H; Matsuno, E; Sasai, K; Shibamoto, Y | 1 |
Abe, M; Iwai, H; Murata, R; Oya, N; Shibamoto, Y; Shibata, T; Sugiyama, T | 1 |
Hori, H; Inayama, S; Mori, T; Murayama, C; Nagasawa, H; Nakajima, T; Onoyama, Y; Tada, T | 1 |
Chapman, JD; Golberg, LE; Groshar, D; Hoskinson, M; Mannan, RH; McEwan, AJ; Mercer, JR; Parliament, MB; Urtasun, RC; Wiebe, LI | 1 |
Abe, M; Hiraoka, M; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T; Takagi, T | 1 |
Scobie, M; Threadgill, MD; Wood, PJ | 1 |
Akuta, K; Kinashi, Y; Masunaga, S; Ono, K; Suzuki, M | 1 |
Adams, GE; Horsman, MR; Khalil, AA; Overgaard, J; Steinberg, F; Stratford, IJ; Streffer, C; Wood, PJ | 1 |
Calkins, DP; Kennedy, AS; Novotny, DB; Perez, GM; Raleigh, JA; Thrall, DE; Varia, MA | 1 |
Bellotti, G; Bocchi, EA; Fiorelli, A; Higuchi, ML; Jatene, A; Pileggi, F; Stolf, N; Uip, D; Vieira, ML | 1 |
Ballenger, CA; Calkins-Adams, DP; Fowler, WC; Novotny, DB; Raleigh, JA; Rinker, LH; Varia, MA; Weissler, MC | 1 |
Bussink, J; Hodgkiss, RJ; Kaanders, JH; Marres, HA; Peters, JP; Rijken, PF; van der Kogel, AJ | 1 |
Ballenger, CA; Calkins-Adams, DP; Chou, SC; Novotny, DB; Raleigh, JA; Varia, MA | 1 |
Begg, AC; Geboes, K; Haustermans, K; Hofland, I; Raleigh, J; Van de Pavert, L; Varia, M | 1 |
Bussink, J; de Wilde, PC; Kaanders, JH; Marres, HA; Raleigh, JA; Rijken, PF; van den Hoogen, FJ; van der Kogel, AJ; Wijffels, KI | 1 |
Aquino-Parsons, C; Durand, RE; Luo, C; Olive, PL; Raleigh, JA | 1 |
Bussink, J; Denekamp, J; Ljungkvist, AS; Raleigh, JA; Rijken, PF; Van Der Kogel, AJ | 1 |
Bono, EL; Chou, SC; Raleigh, JA; Thrall, DE; Varia, MA | 1 |
Banáth, JP; Luo, CM; Olive, PL | 1 |
Guérin, RA | 1 |
Bleehen, NM; Owen, LN; White, RA; Workman, P | 1 |
Dische, S | 1 |
Suwiński, J; Watras, J; Wideł, M | 1 |
Fowler, JF; Hill, SA | 1 |
Coleman, CN; Cosmatos, D; Davis, LW; Lee, DJ; Marcial, VA; Phillips, TL; Rubin, P; Wasserman, TH | 1 |
Charreau, I; Chassagne, D; Eschwege, F; Malaise, EP; Sancho-Garnier, H | 2 |
Brown, DQ; Curran, WJ; Evans, SM; Hanks, G; Helfand, S; LaCreta, F; VanWinkle, T | 1 |
Coleman, N; Cosmatos, D; Davis, L; Lee, DJ; Marcial, V; Phillips, T; Stetz, J; Wasserman, TH | 1 |
Abe, M; Fushiki, M; Iwai, H; Nishimoto, S; Sasai, K; Shibamoto, Y; Suyama, S; Takahashi, M; Yukawa, Y | 1 |
Bleehen, NM; Newman, HF; Smithen, CE; Ward, R; Workman, P | 1 |
Wagner, W | 1 |
abd el Baki, H; Akoush, H; Awwad, HK; el Badawy, S; el Moneim Osman, A; Fairchild, K; Zaghloul, M | 1 |
Bennett, MH; Des Rochers, C; Dische, S; Dunphy, EP; Minchinton, AI; Saunders, MI; Stratford, MR; Wardman, P | 1 |
5 review(s) available for azomycin and Carcinoma, Epidermoid
Article | Year |
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[Metabolic tailoring in radiotherapy for head and neck cancer].
Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Clinical Trials as Topic; Diffusion Magnetic Resonance Imaging; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Misonidazole; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Image-Guided; Tumor Burden | 2014 |
The role of PET imaging in overcoming radiobiological challenges in the treatment of advanced head and neck cancer.
Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Cell Proliferation; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Nitroimidazoles; Positron-Emission Tomography; Radioisotopes; Radiotherapy, Image-Guided; Squamous Cell Carcinoma of Head and Neck | 2012 |
Alternative PET tracers in head and neck cancer. A review.
Topics: Amino Acids; Antibodies, Monoclonal; Carbon Radioisotopes; Carcinoma, Squamous Cell; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Misonidazole; Nitroimidazoles; Nucleosides; Positron-Emission Tomography; Radiopharmaceuticals | 2013 |
Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers.
Topics: Antigens, Neoplasm; Biomarkers, Tumor; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; DNA-Binding Proteins; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Neoplasm Proteins; Nitroimidazoles; Nuclear Proteins; Oxygen; Radiation-Sensitizing Agents; Transcription Factors; Treatment Outcome; Vascular Endothelial Growth Factor A | 2003 |
Radiosensitizers in the treatment of squamous cell carcinoma of the head and neck.
Topics: Animals; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Hypoxia; Metronidazole; Mice; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents | 1977 |
21 trial(s) available for azomycin and Carcinoma, Epidermoid
Article | Year |
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Hypoxia-guided adaptive radiation dose escalation in head and neck carcinoma: a planning study.
Topics: Aged; Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Female; Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy Planning, Computer-Assisted; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed | 2015 |
Prognostic value of PET/CT with (18)F-fluoroazomycin arabinoside for patients with head and neck squamous cell carcinomas receiving chemoradiotherapy.
Topics: Carcinoma, Squamous Cell; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Prognosis; Squamous Cell Carcinoma of Head and Neck | 2016 |
Initial results of hypoxia imaging using 1-alpha-D: -(5-deoxy-5-[18F]-fluoroarabinofuranosyl)-2-nitroimidazole ( 18F-FAZA).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Female; Fluorine Radioisotopes; Glioma; Head and Neck Neoplasms; Humans; Hypoxia; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Young Adult | 2009 |
Evaluating repetitive 18F-fluoroazomycin-arabinoside (18FAZA) PET in the setting of MRI guided adaptive radiotherapy in cervical cancer.
Topics: Adaptation, Biological; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Nitroimidazoles; Periodicity; Pilot Projects; Positron-Emission Tomography; Radiography; Radiotherapy Dosage; Radiotherapy, Computer-Assisted; Uterine Cervical Neoplasms | 2010 |
FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: results from the DAHANCA 24 trial.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Lymph Nodes; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Prognosis; Tomography, X-Ray Computed | 2012 |
Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Carbon Dioxide; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Proteins; Niacinamide; Nitroimidazoles; Oxygen; Predictive Value of Tests; Treatment Outcome | 2002 |
Quantifying tumour hypoxia with fluorine-18 fluoroerythronitroimidazole ([18F]FETNIM) and PET using the tumour to plasma ratio.
Topics: Blood Flow Velocity; Carcinoma, Squamous Cell; Cell Hypoxia; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Muscle, Skeletal; Nitroimidazoles; Oxygen Radioisotopes; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed | 2003 |
The fate of hypoxic (pimonidazole-labelled) cells in human cervix tumours undergoing chemo-radiotherapy.
Topics: Adult; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Combined Modality Therapy; Female; Humans; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Spheroids, Cellular; Uterine Cervical Neoplasms | 2006 |
Determination of tumour hypoxia with [18F]EF3 in patients with head and neck tumours: a phase I study to assess the tracer pharmacokinetics, biodistribution and metabolism.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypoxia; Laryngeal Neoplasms; Male; Middle Aged; Nitroimidazoles; Pharyngeal Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution | 2008 |
Misonidazole combined with radiotherapy in the treatment of inoperable squamous cell carcinoma of the lung. A double-blind randomized trial.
Topics: Aged; Carcinoma, Squamous Cell; Double-Blind Method; Esophagitis; Humans; Lung Neoplasms; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Placebos; Pneumonia; Radiation Injuries; Radiotherapy Dosage; Random Allocation; Vomiting | 1983 |
A study of the effect of misonidazole in conjunction with radiotherapy for the treatment of head and neck cancer. MRC working party on misonidazole in head and neck cancer.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Radiotherapy; Radiotherapy Dosage; Random Allocation | 1984 |
Successful prophylaxis with tinidazole of infection after major head and neck surgery for malignant disease.
Topics: Aged; Bacteria; Carcinoma, Squamous Cell; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Nitroimidazoles; Pharyngeal Neoplasms; Prospective Studies; Surgical Wound Infection; Tinidazole | 1984 |
Primary tumor control after radiotherapy for carcinoma of the bronchus.
Topics: Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Double-Blind Method; Humans; Misonidazole; Neoplasm Metastasis; Nitroimidazoles; Radiation Tolerance | 1984 |
The treatment of locally advanced head and neck cancer with misonidazole, hyperbaric oxygen and irradiation: an interim report.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Middle Aged; Misonidazole; Nitroimidazoles; Pilot Projects; Prospective Studies; Radiation-Sensitizing Agents; Random Allocation | 1984 |
Hyperfractionated radiotherapy with or without misonidazole: results of a prospective randomized study in stage III-IV squamous cell carcinoma of the head and neck.
Topics: Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cobalt Radioisotopes; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Prospective Studies; Radiation-Sensitizing Agents; Radioisotope Teletherapy; Radiotherapy Dosage; Random Allocation | 1984 |
A trial of Ro 03-8799 (pimonidazole) in carcinoma of the uterine cervix: an interim report from the Medical Research Council Working Party on advanced carcinoma of the cervix.
Topics: Adolescent; Adult; Aged; Blood Transfusion; Brachytherapy; Carcinoma, Squamous Cell; Diarrhea; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy Dosage; Remission Induction; Survival Rate; Uterine Cervical Neoplasms; Vomiting | 1993 |
A clinical study of hypoxia and metallothionein protein expression in squamous cell carcinomas.
Topics: Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Metallothionein; Neoplasm Staging; Nitroimidazoles; Proliferating Cell Nuclear Antigen; Protein Precursors; Uterine Cervical Neoplasms | 2000 |
Logistics in designing clinical trials for etanidazole (SR 2508): an RTOG experience.
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Etanidazole; Head and Neck Neoplasms; Humans; Nitroimidazoles; Radiation-Sensitizing Agents; Research Design | 1992 |
First analysis of tumor regression for the European randomized trial of etanidazole combined with radiotherapy in head and neck carcinomas.
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Etanidazole; Female; Head and Neck Neoplasms; Humans; Male; Nitroimidazoles; Radiation-Sensitizing Agents | 1992 |
Progress report of a phase II and a phase III trial with etanidazole (SR-2508): a multicentre European study.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Evaluation; Etanidazole; Europe; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Radiation-Sensitizing Agents | 1991 |
Clinical trials with etanidazole (SR-2508) by the Radiation Therapy Oncology Group (RTOG).
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Evaluation; Etanidazole; Head and Neck Neoplasms; Humans; Nitroimidazoles; Radiation-Sensitizing Agents | 1991 |
98 other study(ies) available for azomycin and Carcinoma, Epidermoid
Article | Year |
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Influence of FAZA PET hypoxia and HPV-status for the outcome of head and neck squamous cell carcinoma (HNSCC) treated with radiotherapy: Long-term results from the DAHANCA 24 trial (NCT01017224).
Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Head and Neck Neoplasms; Humans; Hypoxia; Neoplasm Recurrence, Local; Nitroimidazoles; Papillomavirus Infections; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck | 2020 |
Noninvasive Imaging of Cycling Hypoxia in Head and Neck Cancer Using Intrinsic Susceptibility MRI.
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Contrast Media; Female; Head and Neck Neoplasms; Humans; Lymph Nodes; Magnetic Resonance Imaging; Male; Mice; Neovascularization, Pathologic; Nitroimidazoles; Radiation Tolerance; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Xenograft Model Antitumor Assays | 2017 |
Correlation analysis of [
Topics: Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Middle Aged; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Prognosis; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Small Cell Lung Carcinoma | 2017 |
Optical spectroscopic sensing of tumor hypoxia.
Topics: Animals; Biosensing Techniques; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Hemoglobins; Humans; Mice; Mice, Nude; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Spectrum Analysis; Tumor Cells, Cultured; Tumor Hypoxia | 2018 |
PET imaging of tumor hypoxia using 18F-labeled pimonidazole.
Topics: Animals; Carcinoma, Squamous Cell; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Hypoxia; Mammary Neoplasms, Animal; Mice; Mice, Inbred C3H; Mice, Nude; Nitroimidazoles; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Tumor Cells, Cultured | 2013 |
Hypoxia-inducible factor pathway inhibition resolves tumor hypoxia and improves local tumor control after single-dose irradiation.
Topics: Amines; Animals; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Nucleus; Dose Fractionation, Radiation; Electron Transport Complex I; Female; Heterografts; Humans; Hypoxia-Inducible Factor 1; Ki-67 Antigen; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Random Allocation; Tumor Microenvironment | 2014 |
A prospective clinical study of ¹⁸F-FAZA PET-CT hypoxia imaging in head and neck squamous cell carcinoma before and during radiation therapy.
Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals | 2014 |
Dynamics of tumor hypoxia assessed by 18F-FAZA PET/CT in head and neck and lung cancer patients during chemoradiation: possible implications for radiotherapy treatment planning strategies.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Hypoxia; Chemoradiotherapy; Cohort Studies; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Radiotherapy Planning, Computer-Assisted; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed | 2014 |
The Effects of Pulsed Radiation Therapy on Tumor Oxygenation in 2 Murine Models of Head and Neck Squamous Cell Carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Coloring Agents; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Heterografts; Mice; Mice, Nude; Misonidazole; Neoplasm Recurrence, Local; Nitroimidazoles; Oxygen Consumption; Positron-Emission Tomography; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck; Tumor Burden | 2015 |
Assessment of hypoxic subvolumes in laryngeal cancer with (18)F-fluoroazomycinarabinoside ((18)F-FAZA)-PET/CT scanning and immunohistochemistry.
Topics: Aged; Aged, 80 and over; Biomarkers; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypoxia; Laryngeal Neoplasms; Laryngectomy; Male; Middle Aged; Multimodal Imaging; Neoplasm Recurrence, Local; Nitroimidazoles; Pilot Projects; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed | 2015 |
Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs.
Topics: Activation, Metabolic; Antineoplastic Agents; Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Chemoradiotherapy; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Head and Neck Neoplasms; High-Throughput Screening Assays; Humans; Neoplasm Proteins; Nitroimidazoles; Papillomaviridae; Papillomavirus Infections; Phosphoramide Mustards; Prodrugs; Retrospective Studies; RNA Interference; RNA, Messenger; RNA, Small Interfering; Tirapazamine; Triazines; Tumor Microenvironment; Tumor Stem Cell Assay | 2015 |
Correlation of FMISO simulations with pimonidazole-stained tumor xenografts: A question of O2 consumption?
Topics: Animals; Benzimidazoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Computer Simulation; Feasibility Studies; Fluorescent Antibody Technique; Head and Neck Neoplasms; Humans; Hypoxia; Mice, Nude; Misonidazole; Models, Biological; Neoplasm Transplantation; Nitroimidazoles; Oxygen Consumption; Platelet Endothelial Cell Adhesion Molecule-1; Tumor Microenvironment | 2016 |
Resolution in PET hypoxia imaging: voxel size matters.
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Mice; Mice, Nude; Microscopy, Fluorescence; Necrosis; Neoplasms, Experimental; Nitroimidazoles; Positron-Emission Tomography | 2008 |
Core needle biopsies for determination of the microenvironment in individual tumours for longitudinal radiobiological studies.
Topics: Animals; Biopsy, Needle; Carcinoma, Squamous Cell; Confidence Intervals; Disease Models, Animal; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Environment; Female; Humans; Hypoxia; Immunohistochemistry; Longitudinal Studies; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Probability; Radiobiology; Random Allocation; Reference Values | 2009 |
Hypoxia in larynx carcinomas assessed by pimonidazole binding and the value of CA-IX and vascularity as surrogate markers of hypoxia.
Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Biomarkers; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Humans; Immunohistochemistry; Laryngeal Neoplasms; Male; Middle Aged; Nitroimidazoles; Radiation-Sensitizing Agents | 2009 |
Can hypoxia-PET map hypoxic cell density heterogeneity accurately in an animal tumor model at a clinically obtainable image contrast?
Topics: Animals; Carcinoma, Squamous Cell; Cell Count; Cell Hypoxia; Disease Models, Animal; Female; Hypoxia; Mice; Mice, Inbred C3H; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Radiopharmaceuticals; Random Allocation; Sensitivity and Specificity; Tissue Distribution | 2009 |
Co-localisation of hypoxia and perfusion markers with parameters of glucose metabolism in human squamous cell carcinoma (hSCC) xenografts.
Topics: Animals; Benzimidazoles; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Female; Fluorescent Dyes; Glucose; Humans; Hypoxia; Lactic Acid; Male; Mice; Mice, Nude; Microscopy, Fluorescence; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents; Transplantation, Heterologous | 2009 |
Correlating quantitative MR measurements of standardized tumor lines with histological parameters and tumor control dose.
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Disease Models, Animal; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Humans; Immunohistochemistry; Lactic Acid; Magnetic Resonance Imaging; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Oxygen Consumption; Radiation Dosage; Radiation-Sensitizing Agents; Sensitivity and Specificity; Transplantation, Heterologous | 2010 |
Radiobiological hypoxia, histological parameters of tumour microenvironment and local tumour control after fractionated irradiation.
Topics: Animals; Carcinoma, Squamous Cell; Cell Division; Cell Hypoxia; Confidence Intervals; Disease Models, Animal; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Radiobiology; Transplantation, Heterologous; Tumor Microenvironment | 2010 |
Effect of cetuximab and fractionated irradiation on tumour micro-environment.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Carcinoma, Squamous Cell; Cell Line, Tumor; Cetuximab; Combined Modality Therapy; Dose Fractionation, Radiation; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Male; Mice; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents; Signal Transduction; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2010 |
Assessing hypoxia in animal tumor models based on pharmocokinetic analysis of dynamic FAZA PET.
Topics: Animals; Carcinoma, Squamous Cell; Female; Gingival Neoplasms; Humans; Hypoxia; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Transplantation, Heterologous; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2010 |
Exploratory study of the prognostic value of microenvironmental parameters during fractionated irradiation in human squamous cell carcinoma xenografts.
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Dose Fractionation, Radiation; Humans; Mice; Mice, Nude; Nitroimidazoles; Prognosis; Radiation-Sensitizing Agents; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2011 |
Perfusion estimated with rapid dynamic contrast-enhanced magnetic resonance imaging correlates inversely with vascular endothelial growth factor expression and pimonidazole staining in head-and-neck cancer: a pilot study.
Topics: Aged; Algorithms; Carcinoma, Squamous Cell; Cell Hypoxia; Coloring Agents; Contrast Media; Female; Head and Neck Neoplasms; Humans; Kinetics; Magnetic Resonance Imaging; Male; Middle Aged; Models, Biological; Neoplasm Proteins; Neovascularization, Pathologic; Nitroimidazoles; Pilot Projects; Real-Time Polymerase Chain Reaction; Tumor Burden; Vascular Endothelial Growth Factor A | 2011 |
Measuring tumor hypoxia with ¹⁸F-FETNIM PET in esophageal squamous cell carcinoma: a pilot clinical study.
Topics: Carcinoma, Squamous Cell; Chemoradiotherapy; Esophageal Neoplasms; Female; Fluorine Radioisotopes; Humans; Hypoxia; Logistic Models; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Oxygen; Pilot Projects; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; ROC Curve; Tomography, X-Ray Computed; Treatment Outcome | 2012 |
Inhibition of tumor lactate oxidation: consequences for the tumor microenvironment.
Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cinnamates; Female; Fluorodeoxyglucose F18; Glucose; Glycolysis; Head and Neck Neoplasms; Immunoenzyme Techniques; Lactates; Linear Models; Luminescent Measurements; Mice; Mice, Nude; Monocarboxylic Acid Transporters; Nitroimidazoles; Oxidation-Reduction; Symporters; Tumor Microenvironment; Uterine Cervical Neoplasms | 2011 |
Expression of EGFR under tumor hypoxia: identification of a subpopulation of tumor cells responsible for aggressiveness and treatment resistance.
Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Disease-Free Survival; ErbB Receptors; Head and Neck Neoplasms; Humans; Nitroimidazoles; Prognosis; Radiation Tolerance; Radiation-Sensitizing Agents | 2012 |
Copper-64-diacetyl-bis(N(4)-methylthiosemicarbazone) pharmacokinetics in FaDu xenograft tumors and correlation with microscopic markers of hypoxia.
Topics: Animals; Autoradiography; Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Coordination Complexes; Head and Neck Neoplasms; Humans; Immunohistochemistry; Muscles; Nitroimidazoles; Organometallic Compounds; Partial Pressure; Radionuclide Imaging; Rats; Rats, Nude; Thiosemicarbazones; Tissue Distribution; Transplantation, Heterologous; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2012 |
Activation of AKT by hypoxia: a potential target for hypoxic tumors of the head and neck.
Topics: Animals; Blotting, Western; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; ErbB Receptors; Fluorescent Antibody Technique; Head and Neck Neoplasms; Heterocyclic Compounds, 3-Ring; Humans; Hypoxia; Mice; Mice, Inbred BALB C; Mice, Nude; Nitroimidazoles; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Radiation-Sensitizing Agents; Radiotherapy; Receptor, ErbB-2; Signal Transduction; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2012 |
Prognostic value of HIF-1α expression during fractionated irradiation.
Topics: Animals; Biomarkers, Tumor; Blotting, Western; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Dose Fractionation, Radiation; Female; Gene Expression; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Otorhinolaryngologic Neoplasms; Prognosis; Radiation-Sensitizing Agents; Statistics as Topic; Transplantation, Heterologous | 2012 |
HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors.
Topics: Carcinoma, Squamous Cell; Dimerization; Dose-Response Relationship, Drug; Head and Neck Neoplasms; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Idoxuridine; Immunohistochemistry; Ki-67 Antigen; Neovascularization, Pathologic; Nitroimidazoles; Nucleic Acid Synthesis Inhibitors; Perfusion; Transcription Factors; Treatment Outcome | 2002 |
Orally administered pimonidazole to label hypoxic tumor cells.
Topics: Administration, Oral; Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Flow Cytometry; Humans; Male; Mice; Mice, SCID; Neoplasm Transplantation; Nitroimidazoles; Transplantation, Heterologous; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2002 |
GLUT-1 and CAIX as intrinsic markers of hypoxia in carcinoma of the cervix: relationship to pimonidazole binding.
Topics: Adult; Antigens, Neoplasm; Biomarkers; Biopsy; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; DNA-Binding Proteins; Energy Metabolism; Female; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Microelectrodes; Middle Aged; Monosaccharide Transport Proteins; Neoplasm Proteins; Nitroimidazoles; Nuclear Proteins; Observer Variation; Oxygen; Partial Pressure; Radiation-Sensitizing Agents; Reproducibility of Results; Transcription Factors; Uterine Cervical Neoplasms | 2003 |
Hypoxia and differentiation in squamous cell carcinomas of the uterine cervix: pimonidazole and involucrin.
Topics: Biopsy; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line, Tumor; Female; Humans; Hypoxia; Immunohistochemistry; In Situ Hybridization; Metallothionein; Nitroimidazoles; Oxygen; Prognosis; Protein Precursors; Radiation-Sensitizing Agents; RNA, Messenger; Transcription, Genetic; Uterine Cervical Neoplasms | 2003 |
Differentiation-associated staining with anti-pimonidazole antibodies in head and neck tumors.
Topics: Antibodies, Anti-Idiotypic; Biomarkers; Carcinoma, Squamous Cell; Flow Cytometry; Frozen Sections; Head and Neck Neoplasms; Humans; Hypoxia; NAD(P)H Dehydrogenase (Quinone); NADPH-Ferrihemoprotein Reductase; Nitroimidazoles; Prognosis; Radiation-Sensitizing Agents; Staining and Labeling | 2004 |
Quantifying transient hypoxia in human tumor xenografts by flow cytometry.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Colonic Neoplasms; Female; Flow Cytometry; Humans; Mice; Mice, SCID; Nitroimidazoles; Oxygen; Partial Pressure; Transplantation, Heterologous; Uterine Cervical Neoplasms | 2004 |
TX-1877, a bifunctional hypoxic cell radiosensitizer, enhances anticancer host response: immune cell migration and nitric oxide production.
Topics: Animals; Carcinoma, Squamous Cell; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Hypoxia; Cell Movement; Dendritic Cells; Disease Models, Animal; Humans; Mice; Nitric Oxide; Nitroimidazoles; Radiation Tolerance; T-Lymphocytes, Cytotoxic | 2005 |
Does heterogeneity of pimonidazole labelling correspond to the heterogeneity of radiation-response of FaDu human squamous cell carcinoma?
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Dose-Response Relationship, Radiation; Female; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Radiation Tolerance | 2005 |
Erythropoietin receptor is not a surrogate marker for tumor hypoxia and does not correlate with survival in head and neck squamous cell carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Male; Middle Aged; Nitroimidazoles; Receptors, Erythropoietin; Survival Rate | 2005 |
Reevaluation of the radiosensitizing effects of sanazole and nimorazole in vitro and in vivo.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Evaluation, Preclinical; Female; Mice; Nimorazole; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Treatment Outcome; Triazoles | 2005 |
Evaluation of hypoxia-specific cytotoxic bioreductive agent-sodium borocaptate-10B conjugates as 10B-carriers in boron neutron capture therapy.
Topics: Animals; Borohydrides; Boron; Boron Neutron Capture Therapy; Carcinoma, Squamous Cell; Fluorescent Antibody Technique, Indirect; Isotopes; Mice; Molecular Structure; Nitriles; Nitroimidazoles; Quinoxalines; Sulfhydryl Compounds; Tissue Distribution | 2006 |
Imaging hypoxia after oxygenation-modification: comparing [18F]FMISO autoradiography with pimonidazole immunohistochemistry in human xenograft tumors.
Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Fluorine Radioisotopes; Glioblastoma; Head and Neck Neoplasms; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Radionuclide Imaging | 2006 |
Microsatellite alterations in head and neck squamous cell carcinoma and relation to expression of pimonidazole, CA IX and GLUT-1.
Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Base Sequence; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Excitatory Amino Acid Transporter 2; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Loss of Heterozygosity; Male; Microsatellite Instability; Middle Aged; Molecular Sequence Data; Nitroimidazoles | 2006 |
Pimonidazole labelling and response to fractionated irradiation of five human squamous cell carcinoma (hSCC) lines in nude mice: the need for a multivariate approach in biomarker studies.
Topics: Animals; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Dose Fractionation, Radiation; Female; Humans; Imaging, Three-Dimensional; Male; Mice; Mice, Nude; Nitroimidazoles; Prognosis; Treatment Outcome; Xenograft Model Antitumor Assays | 2006 |
Tumour cell proliferation under hypoxic conditions in human head and neck squamous cell carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Biopsy; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Proliferation; Female; Head and Neck Neoplasms; Humans; Idoxuridine; Image Processing, Computer-Assisted; Male; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Nitroimidazoles; Nucleic Acid Synthesis Inhibitors; Radiation-Sensitizing Agents; Treatment Outcome | 2008 |
Identifying and targeting hypoxia in head and neck cancer: a brief overview of current approaches.
Topics: Antigens, Neoplasm; Biomarkers; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Electrodes; Etanidazole; Head and Neck Neoplasms; Humans; Hydrocarbons, Fluorinated; Intracellular Signaling Peptides and Proteins; Mitochondrial Proteins; Neoplasm Proteins; Nitroimidazoles; Osteopontin; Oxygen; Partial Pressure; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 2007 |
Hypoxia imaging with FAZA-PET and theoretical considerations with regard to dose painting for individualization of radiotherapy in patients with head and neck cancer.
Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Feasibility Studies; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Positron-Emission Tomography; Radiotherapy, Intensity-Modulated; Tomography, X-Ray Computed | 2007 |
Imaging hypoxia in xenografted and murine tumors with 18F-fluoroazomycin arabinoside: a comparative study involving microPET, autoradiography, PO2-polarography, and fluorescence microscopy.
Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Fibrosarcoma; Fluorine Radioisotopes; Immunocompromised Host; Immunohistochemistry; Mice; Mice, Inbred C3H; Mice, Nude; Microscopy, Fluorescence; Nitroimidazoles; Oxygen; Polarography; Positron-Emission Tomography; Radiation-Sensitizing Agents; Transplantation, Heterologous | 2008 |
Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome: in regard to Evans et al. (Int J Radiat Oncol Biol Phys 2007;69:1024-1031).
Topics: Carbon Dioxide; Carcinoma, Squamous Cell; Cell Hypoxia; Head and Neck Neoplasms; Humans; Nitroimidazoles; Oxygen; Prognosis; Radiation-Sensitizing Agents; Time Factors | 2008 |
Reduced fractionation and the potential of hypoxic cell sensitizers in irradiation of malignant epithelial tumors.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Misonidazole; Mouth Neoplasms; Nitroimidazoles; Oropharynx; Pharyngeal Neoplasms; Radiation-Sensitizing Agents; Radiotherapy Dosage; Retrospective Studies | 1980 |
[Biological studies of proton irradiation under combination with a hypoxic cell sensitizer].
Topics: Animals; Carcinoma, Squamous Cell; Female; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Protons; Radiotherapy, High-Energy; Skin Neoplasms | 1982 |
The use of misonidazole in association with a three-fractions per day regimen in advanced head and neck epidermoid cancer. A pilot study.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Erythema; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Pilot Projects; Radiotherapy Dosage | 1983 |
Interstitial misonidazole. A preliminary report on a new perspective in clinical radiation sensitization and hypoxic cell chemotherapy.
Topics: Aged; Carcinoma, Squamous Cell; Female; Humans; Injections; Male; Melanoma; Middle Aged; Misonidazole; Nitroimidazoles; Skin Neoplasms | 1984 |
The topical use of misonidazole in bladder cancer.
Topics: Administration, Oral; Administration, Topical; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Humans; Kinetics; Misonidazole; Mucous Membrane; Nitroimidazoles; Urinary Bladder; Urinary Bladder Neoplasms | 1983 |
[Experimental studies on radiosensitization of hypoxic cancer cells].
Topics: Animals; Carcinoma, Squamous Cell; Female; Humans; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Oxygen; Uterine Cervical Neoplasms | 1983 |
[Flow-microfluorometric studies on the effect of misonidazole as a radiosensitizer for human uterine cervical carcinoma transplanted to nude mice].
Topics: Animals; Carcinoma, Squamous Cell; DNA, Neoplasm; Female; Flow Cytometry; Humans; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Uterine Cervical Neoplasms | 1983 |
[Effect of even or uneven dose fractionation regime on murine squamous cell carcinoma with combined use of misonidazole].
Topics: Animals; Carcinoma, Squamous Cell; Combined Modality Therapy; Fibrosarcoma; Mice; Mice, Inbred Strains; Misonidazole; Nitroimidazoles; Radiotherapy Dosage | 1983 |
Fatal misonidazole-induced encephalopathy: an RTOG case report.
Topics: Brain Diseases; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Humans; Middle Aged; Misonidazole; Nitroimidazoles; Palatal Neoplasms; Tongue Neoplasms | 1982 |
Large fraction radiotherapy plus misonidazole for treatment of advanced lung cancer: report of a phase I/II trial.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Nitroimidazoles; Radiotherapy; Radiotherapy Dosage | 1982 |
Misonidazole Neuropathy: a clinical, electrophysiological, and histological study.
Topics: Aged; Carcinoma, Squamous Cell; Electromyography; Female; Humans; Laryngeal Neoplasms; Lung Neoplasms; Male; Median Nerve; Middle Aged; Misonidazole; Nerve Fibers, Myelinated; Nervous System Diseases; Neural Conduction; Neuromuscular Diseases; Nitroimidazoles; Paresthesia; Peroneal Nerve; Pharyngeal Neoplasms; Sensation; Sural Nerve; Tibial Nerve | 1982 |
The feasibility of high-dose multiple daily fractionation and its combination with anoxic cell sensitizers in the treatment of head and neck cancer. A pilot study of the Radiotherapy Group of the EORTC (European Organisation for Research on Treatment of C
Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Pilot Projects; Prognosis; Radiotherapy Dosage | 1982 |
Effects of misonidazole on tumor cell radiation sensitivity and potentially lethal damage repair in vivo and in vitro.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation Tolerance; Time Factors | 1981 |
Pilot study of radiotherapy with misonidazole in head and neck cancer.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nervous System Diseases; Nitroimidazoles; Pilot Projects; Radiotherapy Dosage | 1981 |
Comparison of hyperbaric oxygen and misonidazole in fractionated irradiation of murine tumors.
Topics: Animals; Carcinoma, Squamous Cell; Female; Hyperbaric Oxygenation; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Skin | 1981 |
Phenytoin-induced changes in the pharmacokinetics of misonidazole in radiotherapy patients.
Topics: Carcinoma, Squamous Cell; Esophageal Neoplasms; Half-Life; Head and Neck Neoplasms; Humans; Kinetics; Misonidazole; Nitroimidazoles; Phenytoin; Time Factors | 1981 |
The value of adjuvant misonidazole in the definitive irradiation of advanced head and neck squamous cancer: an RTOG pilot study (#78-02).
Topics: Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Nausea; Neoplasm Recurrence, Local; Neoplasm Staging; Nitroimidazoles; Paresthesia; Pharyngeal Neoplasms; Prognosis | 1981 |
Optical isomers of a new 2-nitroimidazole nucleoside analog (PR-350 series): radiosensitization efficiency and toxicity.
Topics: Animals; Carcinoma, Squamous Cell; Female; Mice; Mice, Inbred C3H; Nitroimidazoles; Nucleosides; Radiation Dosage; Radiation-Sensitizing Agents; Stereoisomerism; Tumor Stem Cell Assay | 1995 |
[Radiosensitizing effects of nitroimidazole derivative, KIN-804].
Topics: Animals; Carcinoma, Squamous Cell; Hydroxamic Acids; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Skin Neoplasms | 1995 |
DNA-targeted 2-nitroimidazoles: in vitro and in vivo studies.
Topics: Animals; Carcinoma, Squamous Cell; Cell Division; CHO Cells; Cricetinae; Cytotoxins; DNA; In Vitro Techniques; Intercalating Agents; Mice; Mice, Inbred C3H; Nitroimidazoles; Organoids; Phenanthridines; Radiation-Sensitizing Agents; Solubility; Structure-Activity Relationship; Tumor Cells, Cultured | 1994 |
Reoxygenation in the SCCVII tumor after KU-2285 sensitization plus single or fractionated irradiation.
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Mice; Mice, Inbred C3H; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents | 1994 |
Comparison of radiosensitizing effect of KU-2285 and SR-2508 at low drug concentrations and doses.
Topics: Animals; Carcinoma, Squamous Cell; Cell Survival; Dose-Response Relationship, Drug; Etanidazole; Female; Mice; Mice, Inbred C3H; Micronucleus Tests; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents | 1994 |
Radiosensitizing activity and pharmacokinetics of multiple dose administered KU-2285 in peripheral nerve tissue in mice.
Topics: Animals; Carcinoma, Squamous Cell; Etanidazole; Female; Male; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Misonidazole; Nitroimidazoles; Peripheral Nerves; Radiation-Sensitizing Agents | 1994 |
KIN-804 vs. KU-2285 as a radiosensitizer for clinical use.
Topics: Animals; Carcinoma, Squamous Cell; Chromosome Aberrations; Female; Humans; Hydroxamic Acids; Mice; Mice, Inbred C3H; Micronucleus Tests; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents | 1994 |
In vivo radiosensitizing effect of nitroimidazole derivative KIN-804.
Topics: Animals; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Hydroxamic Acids; Lethal Dose 50; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents | 1994 |
Imaging tumor hypoxia and tumor perfusion.
Topics: Brain Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Glioblastoma; Head and Neck Neoplasms; Humans; Iodine Radioisotopes; Lung Neoplasms; Male; Nitroimidazoles; Organotechnetium Compounds; Oximes; Sarcoma; Soft Tissue Neoplasms; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon | 1993 |
Comparison of in vivo efficacy of hypoxic cytotoxin tirapazamine and hypoxic cell radiosensitizer KU-2285 in combination with single and fractionated irradiation.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Radiotherapy Dosage; Tirapazamine; Triazines | 1996 |
Uptake and retention of nitroimidazole-carboranes designed for boron neutron capture therapy in experimental murine tumours: detection by 11B magnetic resonance spectroscopy.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Carcinoma, Squamous Cell; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Nitroimidazoles; Sarcoma, Experimental | 1996 |
The radiosensitizing effects of hypoxic cell sensitizer on SCCVII tumors in mice evaluated by highly accurate colony formation assay assisted by microcomputer.
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Etanidazole; Male; Mice; Mice, Inbred C3H; Microcomputers; Misonidazole; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1996 |
A comparison of the physiological effects of RSU1069 and RB6145 in the SCCVII murine tumour.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Disease Models, Animal; Female; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C3H; Misonidazole; Neovascularization, Pathologic; Nitroimidazoles; Oxygen; Phosphorus Radioisotopes | 1996 |
Proliferation and hypoxia in human squamous cell carcinoma of the cervix: first report of combined immunohistochemical assays.
Topics: Adult; Antigens, Nuclear; Biomarkers; Carcinoma, Squamous Cell; Cell Division; Cell Hypoxia; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Nitroimidazoles; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms | 1997 |
Higher incidence of malignant neoplasms after heart transplantation for treatment of chronic Chagas' heart disease.
Topics: Adult; Carcinoma, Squamous Cell; Chagas Cardiomyopathy; Chemoprevention; Chronic Disease; Cocarcinogenesis; Cyclosporine; Female; Follow-Up Studies; Heart Failure; Heart Transplantation; Humans; Immunosuppressive Agents; Incidence; Lung Diseases; Lymphoproliferative Disorders; Male; Mutagens; Neoplasms; Neurilemmoma; Nitroimidazoles; Recurrence; Sarcoma, Kaposi; Skin Neoplasms; Survival Rate; Trypanocidal Agents | 1998 |
Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker.
Topics: Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Endothelial Growth Factors; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Lymphokines; Nitroimidazoles; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Vascular architecture and microenvironmental parameters in human squamous cell carcinoma xenografts: effects of carbogen and nicotinamide.
Topics: Animals; Benzimidazoles; Blood Vessels; Carbon Dioxide; Carcinoma, Squamous Cell; Cell Division; Endothelium, Vascular; Humans; Hypoxia; Laryngeal Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Niacinamide; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Theophylline; Transplantation, Heterologous; Tumor Cells, Cultured | 1999 |
Diffusion limited hypoxia estimated by vascular image analysis: comparison with pimonidazole staining in human tumors.
Topics: Adenocarcinoma; Blood Vessels; Carcinoma, Squamous Cell; Cell Hypoxia; Diffusion; Esophageal Neoplasms; Female; Humans; Image Processing, Computer-Assisted; Nitroimidazoles; Observer Variation; Radiation-Sensitizing Agents; Rectal Neoplasms; Reproducibility of Results; Uterine Cervical Neoplasms | 2000 |
Vascular architecture and hypoxic profiles in human head and neck squamous cell carcinomas.
Topics: Aged; Biomarkers; Biopsy; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Hypoxia; Image Processing, Computer-Assisted; Immunohistochemistry; Laryngeal Neoplasms; Male; Microscopy, Fluorescence; Middle Aged; Nitroimidazoles; Oropharyngeal Neoplasms; Prognosis | 2000 |
Comparison between the comet assay and pimonidazole binding for measuring tumour hypoxia.
Topics: Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; Cell Hypoxia; Comet Assay; Cricetinae; Cricetulus; DNA, Neoplasm; Female; Flow Cytometry; Fluorescein-5-isothiocyanate; Humans; Immunoconjugates; Male; Mice; Mice, Inbred C3H; Mice, Inbred NOD; Mice, SCID; Nitroimidazoles; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2000 |
Changes in tumor hypoxia measured with a double hypoxic marker technique.
Topics: Animals; Benzimidazoles; Biomarkers; Carbon Dioxide; Carcinoma, Squamous Cell; Cell Hypoxia; Endothelium, Vascular; Fluorescent Dyes; Mice; Mice, Inbred BALB C; Mice, Nude; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Tumor Cells, Cultured | 2000 |
Semiquantitative immunohistochemical analysis for hypoxia in human tumors.
Topics: Calibration; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Nitroimidazoles; Observer Variation; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms | 2001 |
Local hypoxia is produced at sites of intratumour injection.
Topics: Animals; Benzimidazoles; Carcinoma, Squamous Cell; Cell Hypoxia; Comet Assay; DNA Damage; Humans; Injections; Mice; Nitroimidazoles; Radiation-Sensitizing Agents | 2002 |
[The use of potentiating agents in megavoltage therapy of non-resected localized carcinoma of the lung (author's transl)].
Topics: Carcinoma, Squamous Cell; Dose-Response Relationship, Radiation; Hot Temperature; Humans; Lung Neoplasms; Neutrons; Nitroimidazoles; Radiotherapy, High-Energy | 1979 |
The penetration of misonidazole into spontaneous canine tumours.
Topics: Adenocarcinoma; Anesthesia, Intravenous; Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Dog Diseases; Dogs; Female; Fibrosarcoma; Half-Life; Lymphoma, Non-Hodgkin; Male; Mammary Glands, Animal; Meningioma; Misonidazole; Neoplasms; Nitroimidazoles; Osteosarcoma; Pentobarbital | 1979 |
Response of the solid Guerin epitheliomas of rats to fractionated irradiation and a new 4-nitroimidazole.
Topics: Animals; Carcinoma, Squamous Cell; Male; Metronidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Rats; Rats, Inbred Strains; Time Factors; Transplantation, Homologous | 1979 |
Radiosensitizing and cytocidal effects on hypoxic cells of RO-07-0582, and repair of x-ray injury, in an experimental mouse tumour.
Topics: Animals; Carcinoma, Squamous Cell; Hypoxia; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Skin Neoplasms; Transplantation, Homologous | 1977 |
Technique, pharmacokinetics, toxicity, and efficacy of intratumoral etanidazole and radiotherapy for treatment of spontaneous feline oral squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cat Diseases; Cats; Combined Modality Therapy; Etanidazole; Mouth Neoplasms; Necrosis; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy; Radiotherapy Dosage | 1991 |
In vivo radiosensitizing activity of a new fluorinated hypoxic cell radiosensitizer, KU-2285, in combination with radiation dose fractionation.
Topics: Animals; Carcinoma, Squamous Cell; Cell Survival; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy Dosage | 1991 |
Lack of stereoselectivity in the pharmacokinetics and metabolism of the radiosensitizer Ro 03-8799 in man.
Topics: Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nitroimidazoles; Radiation-Sensitizing Agents; Stereoisomerism | 1991 |
[New results with delayed progression in the cell cycle of solid squamous cell carcinomas of the head-neck area after single and fractionated irradiation with cobalt-60 and neutrons].
Topics: Animals; Carcinoma, Squamous Cell; Cell Cycle; Cobalt Radioisotopes; Head and Neck Neoplasms; Neoplasm Transplantation; Neutrons; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors; Transplantation, Heterologous | 1990 |
Pharmacokinetics of etanidazole (SR-2508) in bladder and cervical cancer: evidence of diffusion from urine.
Topics: Carcinoma, Squamous Cell; Diffusion; Etanidazole; Female; Humans; Nitroimidazoles; Radiation-Sensitizing Agents; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms | 1989 |
A comparison of the tumour concentrations obtainable with misonidazole and Ro 03-8799.
Topics: Adult; Aged; Animals; Carcinoma, Squamous Cell; Cricetinae; Cricetulus; Female; Humans; Male; Melanoma; Mice; Middle Aged; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms | 1986 |