Page last updated: 2024-10-23

azobenzene and Amaurosis

azobenzene has been researched along with Amaurosis in 5 studies

azobenzene: photosensor molecule known to undergo reversible isomerization from trans to cis on illumination with photons of appropriate wavelength; RN given refers to cpd without isomeric designation; structure
(E)-azobenzene : The (E)-isomer of azobenzene.
(Z)-azobenzene : The (Z)-isomer of azobenzene.
azobenzene : A molecule whose structure comprises two phenyl rings linked by a N=N double bond; the parent compound of the azobenzene class of compounds.

Research Excerpts

ExcerptRelevanceReference
"Azobenzene photoswitches confer light sensitivity onto retinal ganglion cells (RGCs) in blind mice, making these compounds promising candidates as vision-restoring drugs in humans with degenerative blindness."3.83How Azobenzene Photoswitches Restore Visual Responses to the Blind Retina. ( Denlinger, B; Fletcher, EL; Fletcher, RB; Helft, Z; Kramer, RH; Malis, J; Meseguer, V; Telias, M; Tochitsky, I; Vessey, KA, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Laprell, L1
Tochitsky, I4
Kaur, K1
Manookin, MB1
Stein, M1
Barber, DM1
Schön, C1
Michalakis, S1
Biel, M1
Kramer, RH4
Sumser, MP1
Trauner, D2
Van Gelder, RN2
Kienzler, MA1
Isacoff, E1
Helft, Z1
Meseguer, V1
Fletcher, RB1
Vessey, KA1
Telias, M1
Denlinger, B1
Malis, J1
Fletcher, EL1
Drivas, TG1
Bennett, J1
Polosukhina, A1
Litt, J1
Nemargut, J1
Sychev, Y1
De Kouchkovsky, I1
Huang, T1
Borges, K1

Reviews

1 review available for azobenzene and Amaurosis

ArticleYear
Restoring Vision to the Blind with Chemical Photoswitches.
    Chemical reviews, 2018, 11-14, Volume: 118, Issue:21

    Topics: Animals; Azo Compounds; Blindness; Gene Expression Regulation; Humans; Light; Optogenetics; Photoche

2018

Other Studies

4 other studies available for azobenzene and Amaurosis

ArticleYear
Photopharmacological control of bipolar cells restores visual function in blind mice.
    The Journal of clinical investigation, 2017, Jun-30, Volume: 127, Issue:7

    Topics: Animals; Azo Compounds; Blindness; Mice; Mice, Knockout; Quaternary Ammonium Compounds; Recovery of

2017
How Azobenzene Photoswitches Restore Visual Responses to the Blind Retina.
    Neuron, 2016, Oct-05, Volume: 92, Issue:1

    Topics: Action Potentials; Animals; Azo Compounds; Blindness; Ion Channels; Mice; Photic Stimulation; Photor

2016
The bionic retina: a small molecule with big potential for visual restoration.
    Neuron, 2012, Jul-26, Volume: 75, Issue:2

    Topics: Animals; Azo Compounds; Blindness; Photosensitizing Agents; Quaternary Ammonium Compounds; Retinal N

2012
Photochemical restoration of visual responses in blind mice.
    Neuron, 2012, Jul-26, Volume: 75, Issue:2

    Topics: Animals; Azo Compounds; Blindness; Disease Models, Animal; Mice; Photosensitizing Agents; Quaternary

2012