Page last updated: 2024-08-24

azimilide and Arrhythmia

azimilide has been researched along with Arrhythmia in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (27.78)	18.2507
2000's	24 (66.67)	29.6817
2010's	2 (5.56)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Jia, L; Sun, H	1
Al-Khalidi, HR; Brum, JM; Dorian, P; Dunnmon, PM; Hohnloser, SH; Holroyde, MJ; Kowey, P; Pratt, CM	1
Cannom, DS; Gidney, B	1
Ducroq, J; Legrand, JC; Puddu, PE; Rouet, R; Sallé, L	1
Tang, YQ; Wang, XJ; Yang, Q; You, QD	1
Grönefeld, GC; Hohnloser, SH	1
Pratt, CM	1
Li, WZ	1
Al-Khalidi, HR; Brum, JM; Camm, AJ; Holroyde, MJ; Karam, R; Pratt, CM; Schwartz, PJ; Sonnenblick, EH; Spyt, MJ	1
Dong, DL; Du, ZM; Li, Z; Song, WH; Wang, HZ; Yang, BF	1
Brendorp, B; Elming, H; Køber, L; Pedersen, OD; Pehrson, S; Torp-Petersen, C	1
Carlson, M	1
Ducouret, P; Ducroq, J; Gérard, JL; Puddu, PE; Rouet, R; Sallé, L; Tabourel, C	1
Connolly, S; Kerr, C; Kowey, P; Page, RL; Pritchett, EL; Wilkinson, WE	1
Carlsson, L; Jacobson, I; Löfberg, L	1
Al-Khalidi, HR; Borggrefe, M; Brum, JM; Camm, AJ; Dorian, P; Holroyde, MJ; Marcello, SR; Pratt, CM; Schwartz, PJ	1
Guo, D; Kowey, PR; Liu, T; Wu, Y; Yan, GX; Zhao, X	1
Grant, AO; Tranquillo, J	1
Connolly, S; Page, RL; Pritchett, EL; Wilkinson, WE	1
Sharma, S	1
Brooks, RR; Carpenter, JF; Maynard, AE; Miller, KE	1
Brooks, RR; Drexler, AP; Micklas, JM	1
Benn, DR; Kostreva, DR; Lowe, ER; Maynard, AE; Mittelstadt, SW	1
Camm, AJ; Karam, R; Pratt, CM	1
Brooks, RR; Corey, AE; Karam, R; Marcello, S; Moore, A	1
Sager, PT	2
Chino, D; Hashimoto, K; Xue, Y; Yamada, C	1
Dorian, P; Newman, D; Qi, XQ	1
Al-Khalidi, H; Brooks, RR; Drexler, AP; Kostreva, DR; Maynard, AE	1
Clemett, D; Markham, A	1
Abrol, R; Page, RL	1
Camm, AJ	1
Reiffel, JA	1

Reviews

10 review(s) available for azimilide and Arrhythmia

Article	Year
[The research practice of anti-arrhythmic agents targeting on potassium ion channel]. Yao xue xue bao = Acta pharmaceutica Sinica, 2011, Volume: 46, Issue:1 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dronedarone; Humans; Hydantoins; Imidazolidines; Molecular Structure; Piperazines; Potassium Channel Blockers; Potassium Channels	2011
[Drug therapy of ventricular arrhythmias - a contemporary perspective]. Deutsche medizinische Wochenschrift (1946), 2002, Oct-25, Volume: 127, Issue:43 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Death, Sudden, Cardiac; Defibrillators, Implantable; Double-Blind Method; Follow-Up Studies; Heart Failure; Heart Ventricles; Humans; Hydantoins; Imidazoles; Imidazolidines; Meta-Analysis as Topic; Piperazines; Placebos; Primary Prevention; Prospective Studies; Quality of Life; Randomized Controlled Trials as Topic; Risk Factors; Time Factors	2002
Pure class III agents for prevention of sudden cardiac death. Journal of cardiovascular electrophysiology, 2003, Volume: 14, Issue:9 Suppl Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Comorbidity; Death, Sudden, Cardiac; Europe; Humans; Hydantoins; Imidazoles; Imidazolidines; Middle Aged; Myocardial Infarction; Phenethylamines; Piperazines; Randomized Controlled Trials as Topic; Sotalol; Sulfonamides; Survival Analysis; Treatment Outcome	2003
A benefit-risk assessment of class III antiarrhythmic agents. Expert opinion on drug safety, 2004, Volume: 3, Issue:6 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Combined Modality Therapy; Defibrillators, Implantable; Dronedarone; Heart Conduction System; Humans; Hydantoins; Imidazolidines; Ion Transport; Life Tables; Membrane Potentials; Meta-Analysis as Topic; Phenethylamines; Piperazines; Risk Assessment; Sotalol; Sulfonamides; Survival Analysis; Torsades de Pointes; Treatment Outcome	2004
Antiarrhythmic drugs: present and future. The Journal of the Association of Physicians of India, 2007, Volume: 55 Suppl Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Design; Humans; Hydantoins; Imidazolidines; Ion Channels; Piperazines; Sotalol	2007
Azimilide dihydrochloride, a novel antiarrhythmic agent. The American journal of cardiology, 1998, Mar-19, Volume: 81, Issue:6A Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Humans; Hydantoins; Imidazoles; Imidazolidines; Piperazines; Potassium Channel Blockers	1998
New advances in class III antiarrhythmic drug therapy. Current opinion in cardiology, 1999, Volume: 14, Issue:1 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Denmark; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Postoperative Complications; Potassium Channel Blockers; Randomized Controlled Trials as Topic; Sulfonamides	1999
New advances in class III antiarrhythmic drug therapy. Current opinion in cardiology, 2000, Volume: 15, Issue:1 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiology; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sotalol; Sulfonamides	2000
Azimilide dihydrochloride: a new class III anti-arrhythmic agent. Expert opinion on investigational drugs, 2000, Volume: 9, Issue:11 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Humans; Hydantoins; Imidazoles; Imidazolidines; Piperazines	2000
Clinical differences between the newer antiarrhythmic agents. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2000, Volume: 1 Suppl C Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dronedarone; Heart Conduction System; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sulfonamides	2000

Trials

5 trial(s) available for azimilide and Arrhythmia

Article	Year
Azimilide reduces emergency department visits and hospitalizations in patients with an implantable cardioverter-defibrillator in a placebo-controlled clinical trial. Journal of the American College of Cardiology, 2008, Sep-23, Volume: 52, Issue:13 Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Defibrillators, Implantable; Emergency Service, Hospital; Hospitalization; Humans; Hydantoins; Imidazolidines; Middle Aged; Piperazines	2008
Mortality in patients after a recent myocardial infarction: a randomized, placebo-controlled trial of azimilide using heart rate variability for risk stratification. Circulation, 2004, Mar-02, Volume: 109, Issue:8 Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Double-Blind Method; Female; Heart Rate; Humans; Hydantoins; Imidazoles; Imidazolidines; Life Tables; Male; Middle Aged; Myocardial Infarction; Neutropenia; Piperazines; Potassium Channel Blockers; Risk Factors; Survival Analysis; Torsades de Pointes; Treatment Outcome; Ventricular Dysfunction, Left	2004
Antiarrhythmic efficacy of azimilide in patients with atrial fibrillation. Maintenance of sinus rhythm after conversion to sinus rhythm. American heart journal, 2006, Volume: 151, Issue:5 Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Female; Heart Rate; Humans; Hydantoins; Imidazolidines; Long QT Syndrome; Male; Middle Aged; Piperazines; Syncope; Torsades de Pointes; Treatment Outcome	2006
Azimilide for the treatment of atrial fibrillation, atrial flutter, and paroxysmal supraventricular tachycardia: results of a randomized trial and insights on the concordance of symptoms and recurrent arrhythmias. Journal of cardiovascular electrophysiology, 2008, Volume: 19, Issue:2 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Endpoint Determination; Female; Humans; Hydantoins; Imidazolidines; Male; Piperazines; Secondary Prevention; Tachycardia, Supraventricular; Treatment Outcome	2008
The azimilide post-infarct survival evaluation (ALIVE) trial. The American journal of cardiology, 1998, Mar-19, Volume: 81, Issue:6A Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Double-Blind Method; Drug Administration Schedule; Female; Heart Rate; Humans; Hydantoins; Imidazoles; Imidazolidines; Male; Middle Aged; Myocardial Infarction; Piperazines; Risk Factors; Stroke Volume; Survival Rate	1998

Other Studies

21 other study(ies) available for azimilide and Arrhythmia

Article	Year
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Azimilide: another effort to prevent implantable cardioverter-defibrillator shocks and their sequelae why it is important and how it works. Journal of the American College of Cardiology, 2008, Sep-23, Volume: 52, Issue:13 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Defibrillators, Implantable; Humans; Hydantoins; Imidazolidines; Piperazines	2008
I(Kr) vs. I(Ks) blockade and arrhythmogenicity in normoxic rabbit Purkinje fibers: does it really make a difference? Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:3 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chromans; Delayed Rectifier Potassium Channels; Epinephrine; Hydantoins; Imidazolidines; In Vitro Techniques; Male; Phenethylamines; Piperazines; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Purkinje Fibers; Rabbits; Sotalol; Sulfonamides	2011
[Progress in the clinical use of anti-arrhythmic drugs (I)]. Zhonghua er ke za zhi = Chinese journal of pediatrics, 2003, Volume: 41, Issue:10 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Clinical Trials as Topic; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sulfonamides	2003
Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels. Basic & clinical pharmacology & toxicology, 2004, Volume: 94, Issue:5 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Delayed Rectifier Potassium Channels; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Hydantoins; Hydrogen-Ion Concentration; Imidazoles; Imidazolidines; Myocardial Ischemia; Oocytes; Patch-Clamp Techniques; Phenethylamines; Piperazines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Sulfonamides; Transfection; Xenopus	2004
Azimilide dihydrochloride. Expert review of cardiovascular therapy, 2005, Volume: 3, Issue:3 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Humans; Hydantoins; Imidazolidines; Piperazines	2005
Electrophysiological effects of azimilide in an in vitro model of simulated-ischemia and reperfusion in guinea-pig ventricular myocardium. European journal of pharmacology, 2005, Aug-22, Volume: 518, Issue:2-3 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chromans; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Ventricles; Hydantoins; Imidazolidines; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Phenethylamines; Piperazines; Potassium Channel Blockers; Sulfonamides; Time Factors	2005
Electrophysiological and antiarrhythmic effects of the novel antiarrhythmic agent AZD7009: a comparison with azimilide and AVE0118 in the acutely dilated right atrium of the rabbit in vitro. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2006, Volume: 8, Issue:7 Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biphenyl Compounds; Dilatation, Pathologic; Heart Atria; Hydantoins; Imidazolidines; In Vitro Techniques; Organic Chemicals; Piperazines; Rabbits	2006
Cumulative experience of azimilide-associated torsades de pointes ventricular tachycardia in the 19 clinical studies comprising the azimilide database. Journal of the American College of Cardiology, 2006, Aug-01, Volume: 48, Issue:3 Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Databases, Factual; Dose-Response Relationship, Drug; Electrocardiography; Female; Humans; Hydantoins; Imidazolidines; Male; Middle Aged; Piperazines; Time Factors; Torsades de Pointes	2006
L-type calcium current reactivation contributes to arrhythmogenesis associated with action potential triangulation. Journal of cardiovascular electrophysiology, 2007, Volume: 18, Issue:2 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels, L-Type; Guinea Pigs; Hydantoins; Imidazolidines; In Vitro Techniques; Myocytes, Cardiac; Nicardipine; Patch-Clamp Techniques; Phenethylamines; Piperazines; Rabbits; Sulfonamides	2007
Action potential and QT prolongation not sufficient to cause Torsade de Pointes: role of action potential triangulation. Journal of cardiovascular electrophysiology, 2007, Volume: 18, Issue:2 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels, L-Type; Guinea Pigs; Hydantoins; Imidazolidines; Myocytes, Cardiac; Nicardipine; Patch-Clamp Techniques; Phenethylamines; Piperazines; Rabbits; Sulfonamides; Torsades de Pointes	2007
Efficacy of the class III antiarrhythmic agent azimilide in rodent models of ventricular arrhythmia. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1996, Volume: 212, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Chloroform; Constriction; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Heart Rate; Hydantoins; Imidazoles; Imidazolidines; Male; Mice; Ouabain; Piperazines; Propranolol; Rats; Rats, Sprague-Dawley	1996
Suppression of inducible ventricular arrhythmias by intravenous azimilide in dogs with previous myocardial infarction. Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:6 Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Dogs; Electrocardiography; Heart; Hemodynamics; Hydantoins; Imidazoles; Imidazolidines; Infusions, Intravenous; Male; Myocardial Infarction; Piperazines; Sotalol	1996
Effects of azimilide and d,l-sotalol on the heart rate and blood pressure response to isoproterenol in anesthetized rats. Cardiovascular drugs and therapy, 1997, Volume: 11, Issue:4 Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Electrocardiography; Heart Rate; Hydantoins; Imidazoles; Imidazolidines; Isoproterenol; Male; Piperazines; Rats; Rats, Sprague-Dawley; Sotalol	1997
Effects of azimilide, a KV(r) and KV(s) blocker, on canine ventricular arrhythmia models. European journal of pharmacology, 1999, Jul-02, Volume: 376, Issue:1-2 Topics: Anesthetics; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Epinephrine; Female; Halothane; Hydantoins; Imidazoles; Imidazolidines; Infusions, Intravenous; Injections, Intravenous; Male; Myocardial Reperfusion Injury; Pentobarbital; Piperazines; Potassium Channel Blockers; Ventricular Fibrillation	1999
Azimilide. NE 10064, Stedicor. Drugs in R&D, 1999, Volume: 1, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Drug Interactions; Drugs, Investigational; Guinea Pigs; Humans; Hydantoins; Imidazoles; Imidazolidines; In Vitro Techniques; Piperazines; Potassium Channel Blockers	1999
[Azimilide: Search for an effective and well-tolerated anti-arrhythmia agent]. Zeitschrift fur Kardiologie, 1999, Volume: 88, Issue:10 Suppl Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death; Death, Sudden; Humans; Hydantoins; Imidazoles; Imidazolidines; Piperazines	1999
The class III effect of azimilide is not associated with reverse use-dependence in open-chest dogs. Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:6 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiac Pacing, Artificial; Delayed Rectifier Potassium Channels; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hydantoins; Imidazoles; Imidazolidines; Male; Piperazines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Refractory Period, Electrophysiological; Ventricular Fibrillation	1999
Proarrhythmia of azimilide and other class III antiarrhythmic agents in the adrenergically stimulated rabbit. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 2000, Volume: 223, Issue:2 Topics: Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Female; Hemodynamics; Hydantoins; Imidazoles; Imidazolidines; Male; Methoxamine; Phenethylamines; Piperazines; Procainamide; Quaternary Ammonium Compounds; Rabbits; Sotalol; Sulfonamides	2000
Azimilide. Drugs, 2000, Volume: 59, Issue:2 Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Headache; Humans; Hydantoins; Imidazoles; Imidazolidines; Piperazines; Recurrence; Torsades de Pointes	2000
Is it rational, reasonable or excessive, and consistently applied? One view of the increasing FDA emphasis on safety first for the release and use of antiarrhythmic drugs for supraventricular arrhythmias. Journal of cardiovascular pharmacology and therapeutics, 2001, Volume: 6, Issue:4 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Approval; Drugs, Generic; Heart Ventricles; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sotalol; Sulfonamides; United States; United States Food and Drug Administration	2001