azilsartan has been researched along with Necrosis* in 1 studies
1 other study(ies) available for azilsartan and Necrosis
Article | Year |
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Azilsartan and its Zn(II) complex. Synthesis, anticancer mechanisms of action and binding to bovine serum albumin.
Azilsartan is the eighth approved member of angiotensin II receptor blockers for hypertension treatment. Considering that some drugs have additional effects when administered, we studied its effects and mechanisms of action on a human lung cancer cell line A549. We have also modified the structure of the drug by complexation with Zn(II) cation and assayed the anticancer effect. The crystal structure of the new binuclear Zn(II) complex, for short [Zn Topics: A549 Cells; Antineoplastic Agents; Antioxidants; Apoptosis; Benzimidazoles; Fibroblasts; Humans; Models, Molecular; Necrosis; Oxadiazoles; Protein Binding; Reactive Oxygen Species; Serum Albumin, Bovine; X-Ray Diffraction; Zinc | 2018 |