azetidyl-2-carboxylic acid has been researched along with Blood Pressure, High in 85 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.35) | 18.7374 |
| 1990's | 2 (2.35) | 18.2507 |
| 2000's | 31 (36.47) | 29.6817 |
| 2010's | 49 (57.65) | 24.3611 |
| 2020's | 1 (1.18) | 2.80 |
| Authors | Studies |
|---|---|
| Okamura, K; Shirai, K; Takamiya, Y; Urata, H; Yano, Y | 1 |
| Jiang, D; Kato, J; Kawagoe, Y; Kitamura, K; Kuwasako, K | 1 |
| Dobashi, S; Fujii, T; Hisatake, S; Ikeda, T; Kabuki, T; Kiuchi, S; Oka, T | 1 |
| Bassossy, HME; Fahmy, A; Hassan, NA; Mahmoud, MF | 1 |
| Hiramatsu, K; Kario, K; Komiya, M; Sato, Y; Shimada, K; Shiosakai, K; Shirayama, M; Takahashi, M | 1 |
| Hiramatsu, K; Kario, K; Komiya, M; Shimada, K; Shiosakai, K; Shirayama, M; Takahashi, M; Uehara, Y | 1 |
| Dohi, Y; Hirota, H; Isaka, N; Ito, M; Kato, T; Kimura, G; Kojima, M; Machida, H; Makino, K; Miyagawa, K; Mizubayashi, R; Mizuno, O; Nakatani, K; Okamoto, S; Okubo, S; Okura, T; Takeuchi, M | 1 |
| Sanae, M; Yasuo, A | 1 |
| Saito, Y; Takami, T | 2 |
| Furusu, A; Kohno, S; Koji, T; Miyazaki, T; Nishino, T; Obata, Y; Sato, Y; Uramatsu, T | 1 |
| Amaya, N; Arakawa, K; Fukuoka, Y; Ishida, K; Lee, JD; Morishita, T; Nakano, A; Tada, H; Uzui, H | 1 |
| Cheng, J; Hamada, T; Hirata, S; Hisatome, I; Igawa, O; Kato, M; Kuwabara, M; Miyazaki, S; Mizuta, E; Moriwaki, Y; Ninomiya, H; Nosaka, Y; Ogino, K; Ohtahara, A; Yamamoto, K; Yamamoto, Y; Yoshida, A | 1 |
| Arakawa, K; Jinnouchi, H; Jinnouchi, T; Kim-Mitsuyama, S; Matsui, K; Ogawa, H | 2 |
| Ikeda, U; Izawa, A; Koyama, J; Miyashita, Y; Motoki, H; Takahashi, M; Tomita, T | 1 |
| Furusho, H; Hamaoka, T; Ikeda, T; Inomata, J; Kaneko, S; Kobayashi, D; Murai, H; Sugiyama, Y; Takamura, M; Takata, S; Usui, S | 1 |
| Grassi, G | 1 |
| Izumikawa, Y; Kato, H; Kojima, K; Kubo, E; Nagura, M; Nosaka, H; Shima, T; Shimada, M; Shiraishi, T; Tanemoto, M; Tomioka, S; Uchida, S; Ueda, S; Yano, H | 1 |
| Imanishi, M; Kitabayashi, C; Kobori, H; Kohno, M; Konishi, Y; Masaki, T; Mori, H; Morikawa, T; Nishiyama, A; Rafiq, K | 1 |
| Date, M; Ishii, K; Ito, H; Iwakura, K; Nagano, T; Nakamura, F; Takiuchi, S | 1 |
| Daida, H; Miyauchi, K; Shimada, K | 1 |
| Kawasaki, S; Kimura, M; Kondo, Y; Nakamura, A; Takihata, M; Terauchi, Y | 1 |
| Kushiro, T; Matsushita, Y; Okutani, Y; Sagawa, K; Saito, I; Sato, Y; Tanaka, Y; Tanigawa, M | 1 |
| Asai, S; Nakayama, T; Nishida, Y; Susa, N; Takahashi, Y; Yada, Y | 1 |
| Hano, T; Iwane, N; Kawabe, T; Koike, Y; Nishihara, K | 1 |
| Fukui, M; Hasegawa, G; Matsumoto, S; Nakamura, N; Oyabu, C; Tanaka, M; Ushigome, E; Ushigome, H; Yamazaki, M; Yokota, I | 1 |
| Matsumoto, C; Shiina, K; Tomiyama, H; Yamada, J; Yamashina, A; Yoshida, M | 1 |
| Fukumoto, Y; Ito, K; Nawata, J; Onoue, N; Shimokawa, H; Sugimura, K; Tada, T; Wang, H; Zhulanqiqige, D | 1 |
| Abe, K; Funakoshi, S; Furusu, A; Harada, T; Kohno, S; Koji, T; Kurashige, T; Miyazaki, M; Nakazawa, M; Nakazawa, Y; Obata, Y; Xia, Z | 1 |
| Araki, S; Hirooka, Y; Kishi, T; Koga, Y; Konno, S; Sunagawa, K | 1 |
| Hatazawa, J; Hougaku, H; Kajimoto, K; Kato, H; Kimura, Y; Kitagawa, K; Oku, N; Sakaguchi, M; Sakoda, S; Tanaka, M | 1 |
| Eguchi, K; Ishikawa, J; Kario, K; Matsui, Y; Miyashita, H; O'Rourke, MF; Shimada, K | 1 |
| Ishii, K; Ito, H; Iwakura, K; Nagano, T; Nakamura, F; Takiuchi, S | 1 |
| Akabane, T; Ishimitsu, T; Masuda, T; Matsuoka, H; Minami, J; Numabe, A; Okamura, A | 1 |
| Arakawa, K; Kuramoto, K; Tanigawara, Y; Yoshihara, K | 1 |
| Daida, H; Fujiwara, Y; Inoue, K; Kawamura, M; Kojima, T; Kurata, T; Miyauchi, K; Nakazato, Y; Okazaki, S; Sumiyoshi, M; Suwa, S; Tanimoto, K; Yamagami, S; Yokoyama, K; Yokoyama, T | 1 |
| Kuramoto, K; Ogihara, T; Saruta, T; Shimada, K | 2 |
| Hirano, T; Okamoto, S; Shiraishi, S; Tomiguchi, S; Uchino, M; Watanabe, M | 1 |
| Ando, C; Inoue, Y; Kakuma, T; Kodama, S; Miyoshi, K; Niimura, H; Nonaka, Y; Okamura, K; Sumi, S; Tsuchiya, Y; Urata, H; Yamanouchi, Y | 1 |
| Doi, M; Hirohata, S; Kaji, Y; Kamikawa, S; Kusachi, S; Miyoshi, T; Ninomiya, Y; Ogawa, H; Sakane, K; Usui, S | 1 |
| Araki, E; Goto, R; Kondo, T; Miyamura, N; Ono, K; Sonoda, K; Takaki, Y; Yasuda, T; Yatsuda, R | 1 |
| Inoue, T; Komoda, H; Node, K | 1 |
| Cao, B; Jia, S; Li, H; Lin, Y; Qu, P; Wang, M; Wu, F; Zhao, X | 1 |
| Fujiwara, N; Kawagoe, Y; Koide, H; Nakamura, T; Sato, E; Takeuchi, M; Ueda, Y; Yamagishi, S | 1 |
| Daida, H; Fujiwara, Y; Hiro, T; Inoue, K; Kawamura, M; Kojima, T; Komiyama, N; Kurata, T; Miyauchi, K; Nakazato, Y; Okazaki, S; Sumiyoshi, M; Suwa, S; Tamura, H; Tanimoto, K; Yamagami, S; Yokoyama, K; Yokoyama, T | 1 |
| Ando, K; Fujita, T; Haneda, M; Ito, S; Kashihara, N; Kishimoto, J; Nangaku, M; Node, K; Shimosawa, T | 1 |
| Abe, M; Maruyama, N; Matsumoto, K; Matsumoto, S; Okada, K; Soma, M | 1 |
| Kaneda, H; Ma, J; Morita, T | 1 |
| Hayashi, K | 1 |
| Daida, H; Fukao, K; Hiki, M; Hirose, K; Kiyanagi, T; Kume, A; Kurata, T; Matsumori, R; Miyazaki, T; Ohsaka, H; Shimada, K | 1 |
| Hirooka, Y; Kishi, T; Ogawa, K; Shinohara, K; Sunagawa, K; Utsumi, H; Yasukawa, K | 1 |
| Inoue, T; Kikuta, T; Kojima, E; Nodaira, Y; Ohno, Y; Okayama, M; Seto, T; Sueyoshi, K; Suzuki, H; Takane, H; Takenaka, T; Watanabe, Y | 1 |
| Hoshide, S; Ishikawa, J; Kario, K; Matsui, Y; O'Rourke, MF; Shimada, K | 1 |
| Bilo, G; Parati, G | 1 |
| Ishikawa, J; Kario, K; Matsui, Y; O'Rourke, MF; Shimada, K | 1 |
| Daikuhara, H; Ishida, T; Kikuchi, F | 1 |
| MacRae, B; Rickards, C; Tzeng, YC | 1 |
| Rich, MW | 1 |
| Daida, H; Miyauchi, K | 1 |
| Abe, K; Kanazawa, M; Kohzuki, M; Kurosawa, H; Minami, N; Saito, T; Yasujima, M; Yoshida, K | 1 |
| Hirai, A; Ichikawa, S; Kanada, S; Kuramoto, K; Nakachi, T; Ogihara, T | 1 |
| Scott, LJ; Wellington, K | 1 |
| Sada, T; Saito, H | 1 |
| Iwao, H; Izumi, Y; Izumiya, Y; Kim-Mitsuyama, S; Yoshida, K; Yoshiyama, M | 1 |
| Inoue, H; Nakamura, K; Yamagishi, S | 1 |
| Ito, T; Kataoka, K; Kim-Mitsuyama, S; Lai, ZF; Ogawa, H; Tanaka, T; Tokutomi, Y; Yamamoto, E; Yamashita, T | 1 |
| Hayashi, K; Iigaya, K; Kumagai, H; Onami, T; Takimoto, C | 1 |
| Inoue, T; Kobayashi, K; Nakamoto, H; Shoda, J; Suzuki, H | 1 |
| Kurabayashi, M; Nakamura, T; Saito, T; Saito, Y | 1 |
| Yamagishi, T | 1 |
| Kanda, T; Matsumoto, M; Morimoto, S; Murai, H; Nakahashi, T; Nishino, T; Nomura, K; Okaishi, K; Okuro, M; Takahashi, T | 1 |
| Nakamoto, M; Ohya, Y; Sakima, A; Takishita, S; Yamazato, M | 1 |
| Inoue, T; Kawagoe, Y; Koide, H; Nakamura, T; Node, K; Sugaya, T; Suzuki, T; Ueda, Y | 1 |
| Eguchi, K; Fukuda, T; Hoshide, S; Ishikawa, J; Kario, K; Numao, T; Shimada, K; Tomizawa, H | 1 |
| Fujitani, Y; Hirose, T; Kanazawa, A; Kawamori, R; Ohmura, C; Sakai, K; Shimizu, T; Uchino, H; Watada, H | 1 |
| Hayashi, A; Kimoto, K | 1 |
| Ito, S; Kawano, T; Koshiba, K; Mikawa, J; Nada, T; Nomura, M | 1 |
| Guo, Q; Ito, O; Kanazawa, M; Kohzuki, M; Kurosawa, H; Minami, N; Mori, N; Nagasaka, M | 1 |
| Koike, H; Miyamoto, M; Oizumi, K | 1 |
| Arita, M; Hashizume, T; Nishio, I; Tanigawa, K; Yamamoto, H | 1 |
| Fukami, M; Fukushige, J; Koike, H; Miyamoto, M; Nishino, H; Oizumi, K | 1 |
| Kimura, T; Koike, H; Miyamoto, M; Nishino, H; Oizumi, K; Sada, T | 1 |
4 review(s) available for azetidyl-2-carboxylic acid and Blood Pressure, High
| Article | Year |
|---|---|
Azelnidipine and glucose tolerance: possible indications and treatment selection for hypertensive patients with metabolic disorders.
Topics: Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Glucose Intolerance; Humans; Hypertension; Metabolic Diseases; Renin-Angiotensin System | 2015 |
Azelnidipine.
Topics: Animals; Azetidinecarboxylic Acid; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Hemodynamics; Humans; Hypertension; Randomized Controlled Trials as Topic | 2003 |
Pharmacological profiles and clinical effects of azelnidipine, a long-acting calcium channel blocker.
Topics: Animals; Antihypertensive Agents; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Heart Rate; Humans; Hypertension | 2003 |
[Novel actions of calcium channel blockers].
Topics: Amlodipine; Animals; Azetidinecarboxylic Acid; Calcium Channel Blockers; Depression; Dihydropyridines; Evidence-Based Medicine; Heart Rate; Humans; Hypertension; Kidney Diseases; Proteinuria; Sympathetic Nervous System | 2006 |
41 trial(s) available for azetidyl-2-carboxylic acid and Blood Pressure, High
| Article | Year |
|---|---|
Kidney-protective effects of azelnidipine versus a diuretic in combination with olmesartan in hypertensive patients with diabetes and albuminuria: a randomized study.
Topics: Adult; Aged; Albuminuria; Antihypertensive Agents; Azetidinecarboxylic Acid; Calcium Channel Blockers; Diabetes Complications; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Therapy, Combination; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hypertension; Imidazoles; Kidney Diseases; Male; Middle Aged; Prognosis; Prospective Studies; Risk Factors; Tetrazoles; Young Adult | 2013 |
Azelnidipine plus olmesartan versus amlodipine plus olmesartan on arterial stiffness and cardiac function in hypertensive patients: a randomized trial.
Topics: Aged; Amlodipine; Azetidinecarboxylic Acid; Diastole; Dihydropyridines; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Middle Aged; Pulse Wave Analysis; Tetrazoles; Vascular Stiffness; Ventricular Function, Left | 2013 |
Effects of combination therapy with olmesartan and azelnidipine on serum osteoprotegerin in patients with hypertension.
Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Biomarkers; Blood Pressure; C-Reactive Protein; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Matrix Metalloproteinase 2; Middle Aged; Osteoprotegerin; Prospective Studies; Tetrazoles | 2014 |
Effects of azelnidipine on uric acid metabolism in patients with essential hypertension.
Topics: Aged; Aged, 80 and over; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Creatinine; Dihydropyridines; Essential Hypertension; Female; Humans; Hypertension; Hyperuricemia; Male; Uric Acid | 2014 |
Sex differences in response to angiotensin II receptor blocker-based therapy in elderly, high-risk, hypertensive Japanese patients: a subanalysis of the OSCAR study.
Topics: Age Factors; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Asian People; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Japan; Male; Prospective Studies; Risk Factors; Sex Factors; Tetrazoles; Treatment Outcome | 2014 |
Impact of azelnidipine and amlodipine on left ventricular mass and longitudinal function in hypertensive patients with left ventricular hypertrophy.
Topics: Adult; Aged; Amlodipine; Analysis of Variance; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Drug Administration Schedule; Echocardiography, Doppler, Pulsed; Female; Follow-Up Studies; Humans; Hypertension; Hypertrophy, Left Ventricular; Image Interpretation, Computer-Assisted; Male; Middle Aged; Prospective Studies; Risk Assessment; Severity of Illness Index; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling | 2014 |
Differential effects of azelnidipine and amlodipine on sympathetic nerve activity in patients with primary hypertension.
Topics: Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Baroreflex; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Essential Hypertension; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Sympathetic Nervous System | 2014 |
Changes in left ventricular relaxation after azelnidipine treatment in hypertensive patients with diabetes: subanalysis of a prospective single-arm multicentre study.
Topics: Adult; Aged; Aged, 80 and over; Azetidinecarboxylic Acid; Calcium Channel Blockers; Diabetic Cardiomyopathies; Dihydropyridines; Echocardiography; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Ventricular Dysfunction, Left; Ventricular Function, Left | 2014 |
Comparison of Azelnidipine and Trichlormethiazide in Japanese Type 2 Diabetic Patients with Hypertension: The COAT Randomized Controlled Trial.
Topics: Aged; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Diuretics; Female; Humans; Hypertension; Japan; Male; Middle Aged; Risk Factors; Treatment Outcome; Trichlormethiazide | 2015 |
Effects of azelnidipine on the autonomic functions and its influence on arterial stiffness and endothelial functions.
Topics: Aged; Arteries; Autonomic Pathways; Azetidinecarboxylic Acid; Brachial Artery; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Double-Blind Method; Endothelium, Vascular; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Pulse; Vasodilation | 2008 |
Hemodynamic influences of azelnidipine, a novel calcium channel blocker, on cerebral circulation in hypertensive patients with ischemic white matter lesions.
Topics: Acetazolamide; Aged; Aged, 80 and over; Azetidinecarboxylic Acid; Blood Pressure; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular Circulation; Dihydropyridines; Diuretics; Female; Humans; Hypertension; Male; Middle Aged; Positron-Emission Tomography; Regional Blood Flow | 2008 |
Differential effects between a calcium channel blocker and a diuretic when used in combination with angiotensin II receptor blocker on central aortic pressure in hypertensive patients.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Aorta; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Single-Blind Method; Tetrazoles; Time Factors; Treatment Outcome | 2009 |
Impact of azelnidipine treatment on left ventricular diastolic performance in patients with hypertension and mild diastolic dysfunction: multi-center study with echocardiography.
Topics: Adult; Aged; Aged, 80 and over; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Natriuretic Peptide, Brain; Ultrasonography; Ventricular Dysfunction, Left; Ventricular Function, Left; Young Adult | 2009 |
Angiotensin-II receptor antagonist combined with calcium channel blocker or diuretic for essential hypertension.
Topics: Adult; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Ankle Brachial Index; Azetidinecarboxylic Acid; Blood Pressure; C-Reactive Protein; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Diuretics; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Hypertension; Imidazoles; Lipoproteins, LDL; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Tetrazoles; Trichlormethiazide | 2009 |
Comparative pharmacodynamics of olmesartan and azelnidipine in patients with hypertension: a population pharmacokinetic/pharmacodynamic analysis.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Clinical Laboratory Techniques; Cross-Over Studies; Dihydropyridines; Female; Humans; Hypertension; Imidazoles; Individuation; Male; Middle Aged; Olmesartan Medoxomil; Population Groups; Tetrazoles | 2009 |
Azelnidipine and amlodipine anti-coronary atherosclerosis trial in hypertensive patients undergoing coronary intervention by serial volumetric intravascular ultrasound analysis in Juntendo university (ALPS-J).
Topics: Adult; Aged; Amlodipine; Azetidinecarboxylic Acid; Calcium Channel Blockers; Coronary Artery Disease; Dihydropyridines; Disease Progression; Double-Blind Method; Endpoint Determination; Female; Humans; Hypertension; Male; Middle Aged; Ultrasonography; Young Adult | 2009 |
A randomized, double-blind, four-arm parallel-group study of the efficacy and safety of azelnidipine and olmesartan medoxomil combination therapy compared with each monotherapy in Japanese patients with essential hypertension: the REZALT study.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Asian People; Azetidinecarboxylic Acid; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dihydropyridines; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Olmesartan Medoxomil; Tetrazoles; Treatment Outcome | 2009 |
Azelnidipine, a long-acting calcium channel blocker, could control hypertension without decreasing cerebral blood flow in post-ischemic stroke patients. A 123I-IMP SPECT follow-up study.
Topics: Aged; Azetidinecarboxylic Acid; Blood Pressure; Brain Ischemia; Calcium Channel Blockers; Cerebral Infarction; Cerebrovascular Circulation; Dihydropyridines; Female; Follow-Up Studies; Functional Laterality; Heart Rate; Humans; Hypertension; Image Processing, Computer-Assisted; Iofetamine; Male; Middle Aged; Prospective Studies; Radiopharmaceuticals; Stroke; Tomography, Emission-Computed, Single-Photon | 2010 |
Combination therapy of calcium channel blocker and angiotensin II receptor blocker reduces augmentation index in hypertensive patients.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Trichlormethiazide | 2010 |
Effects of combination olmesartan medoxomil plus azelnidipine versus monotherapy with either agent on 24-hour ambulatory blood pressure and pulse rate in Japanese patients with essential hypertension: additional results from the REZALT study.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Imidazoles; Male; Middle Aged; Olmesartan Medoxomil; Tetrazoles | 2010 |
Azelnidipine and amlodipine: a comparison of their effects and safety in a randomized double-blinded clinical trial in Chinese essential hypertensive patients.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure Monitoring, Ambulatory; China; Dihydropyridines; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Treatment Outcome | 2010 |
Calcium channel blocker inhibition of AGE and RAGE axis limits renal injury in nondiabetic patients with stage I or II chronic kidney disease.
Topics: Adult; Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Calcium Channel Blockers; Chronic Disease; Dihydropyridines; Female; Glycation End Products, Advanced; Humans; Hypertension; Japan; Kidney; Kidney Diseases; Male; Middle Aged; Proteinuria; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Time Factors; Treatment Outcome | 2011 |
Azelnidipine and amlodipine anti-coronary atherosclerosis trial in hypertensive patients undergoing coronary intervention by serial volumetric intravascular ultrasound analysis in Juntendo University (ALPS-J).
Topics: Amlodipine; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Coronary Artery Disease; Dihydropyridines; Humans; Hypertension; Lipids; Plaque, Atherosclerotic; Ultrasonography, Interventional | 2011 |
Design and rationale of Japanese evaluation between Formula of Azelnidipine and amlodipine add on olmesartan to Get antialbuminuric effect study (J-FLAG) : evaluation of the antialbuminuric effects between calcium channel blocker with sympatholytic action
Topics: Adult; Aged; Albuminuria; Amlodipine; Azetidinecarboxylic Acid; Calcium Channel Blockers; Diabetic Nephropathies; Dihydropyridines; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Middle Aged; Research Design; Sympatholytics; Tetrazoles | 2011 |
Additive antioxidative effects of azelnidipine on angiotensin receptor blocker olmesartan treatment for type 2 diabetic patients with albuminuria.
Topics: Aged; Albuminuria; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles | 2011 |
Effects of Azelnidipine plus OlmesaRTAn versus amlodipine plus olmesartan on central blood pressure and left ventricular mass index: the AORTA study.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Chi-Square Distribution; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Tetrazoles; Time Factors; Treatment Outcome; Ultrasonography | 2011 |
Effects of calcium channel blockers on glucose tolerance, inflammatory state, and circulating progenitor cells in non-diabetic patients with essential hypertension: a comparative study between azelnidipine and amlodipine on glucose tolerance and endotheli
Topics: Adult; Aged; Amlodipine; Azetidinecarboxylic Acid; Blood Glucose; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Endothelium, Vascular; Female; Humans; Hypertension; Inflammation; Male; Middle Aged; Prospective Studies; Stem Cells | 2011 |
Angiotensin II receptor blocker-based therapy in Japanese elderly, high-risk, hypertensive patients.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Japan; Male; Prospective Studies; Single-Blind Method; Survival Analysis; Tetrazoles; Treatment Outcome | 2012 |
Long-term effects of calcium antagonists on augmentation index in hypertensive patients with chronic kidney disease: a randomized controlled study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Renal Insufficiency, Chronic; Time | 2012 |
Combined effect of angiotensin II receptor blocker and either a calcium channel blocker or diuretic on day-by-day variability of home blood pressure: the Japan Combined Treatment With Olmesartan and a Calcium-Channel Blocker Versus Olmesartan and Diuretic
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Tetrazoles; Treatment Outcome | 2012 |
Association of changes in ambulatory arterial stiffness index and pulse wave velocity during antihypertensive treatment: the J-CORE study.
Topics: Aged; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Pulse Wave Analysis; Tetrazoles; Vascular Stiffness | 2012 |
The combination of OLmesartan and a CAlcium channel blocker (azelnidipine) or candesartan and a calcium channel blocker (amlodipine) in type 2 diabetic hypertensive patients: the OLCA study.
Topics: Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Chi-Square Distribution; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Therapy, Combination; Female; Glycated Hemoglobin; Heart Rate; Humans; Hypertension; Imidazoles; Japan; Male; Middle Aged; Tetrazoles; Time Factors; Treatment Outcome | 2012 |
[Azelnidipine and amlodipine anti-coronary atherosclerosis trial in hypertensive patients undergoing coronary intervention by serial volumetric intravascular ultrasound analysis in Juntendo Medical University].
Topics: Aged; Amlodipine; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Coronary Artery Disease; Dihydropyridines; Female; Humans; Hypertension; Male; Percutaneous Coronary Intervention; Plaque, Atherosclerotic; Preoperative Period; Prospective Studies; Ultrasonography, Interventional | 2012 |
Azelnidipine and amlodipine: a comparison of their pharmacokinetics and effects on ambulatory blood pressure.
Topics: Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Physicians' Offices | 2003 |
Azelnidipine. CS 905, Calblock, RS 9054.
Topics: Animals; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Double-Blind Method; Drugs, Investigational; Hypertension; Rats; Rats, Inbred SHR | 2003 |
The newly developed calcium antagonist, azelnidipine, increases drain volume in continuous ambulatory peritoneal dialysis patients.
Topics: Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Creatinine; Cross-Over Studies; Dihydropyridines; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Sympathetic Nervous System; Urine | 2006 |
Efficacy of azelnidipine on home blood pressure and pulse rate in patients with essential hypertension: comparison with amlodipine.
Topics: Aged; Amlodipine; Azetidinecarboxylic Acid; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Physicians' Offices | 2006 |
Azelnidipine reduces urinary protein excretion and urinary liver-type fatty acid binding protein in patients with hypertensive chronic kidney disease.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Amlodipine; Antioxidants; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Deoxyguanosine; Dihydropyridines; Fatty Acid-Binding Proteins; Female; Heart Rate; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Proteinuria | 2007 |
Effects of new calcium channel blocker, azelnidipine, and amlodipine on baroreflex sensitivity and ambulatory blood pressure.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Azetidinecarboxylic Acid; Baroreflex; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prospective Studies | 2007 |
Calcium channel blocker, azelnidipine, reduces lipid hydroperoxides in patients with type 2 diabetes independent of blood pressure.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Ascorbic Acid; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Erythrocytes; Female; Humans; Hypertension; Lipid Peroxides; Male; Middle Aged; Organophosphorus Compounds; Pyrenes; Vitamin E | 2007 |
A new Ca-antagonist, azelnidipine, reduced blood pressure during exercise without augmentation of sympathetic nervous system in essential hypertension: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Aged; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Cross-Over Studies; Dihydropyridines; Double-Blind Method; Exercise; Female; Humans; Hypertension; Male; Middle Aged; Placebos; Sympathetic Nervous System; Vascular Resistance | 1999 |
40 other study(ies) available for azetidyl-2-carboxylic acid and Blood Pressure, High
| Article | Year |
|---|---|
Efficacy and safety of a combination antihypertensive drug (olmesartan plus azelnidipine): "Issues with hypertension studies in real-world practice".
Topics: Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Drug Combinations; Drug Substitution; Female; Humans; Hypertension; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome | 2020 |
Inhibitory effects of losartan and azelnidipine on augmentation of blood pressure variability induced by angiotensin II in rats.
Topics: Angiotensin II; Animals; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Hypertension; Losartan; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Time Factors | 2017 |
Azelnidipine is a useful medication for the treatment of heart failure preserved ejection fraction.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Echocardiography; Female; Heart Failure; Heart Rate; Humans; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain; Radionuclide Imaging; Renin-Angiotensin System; Stroke Volume | 2017 |
Limonin alleviates macro- and micro-vascular complications of metabolic syndrome in rats: A comparative study with azelnidipine.
Topics: Animals; Aorta, Thoracic; Azetidinecarboxylic Acid; Blood Pressure; Dihydropyridines; Dose-Response Relationship, Drug; Fructose; Glycation End Products, Advanced; Hypertension; Insulin Resistance; Limonins; Male; Metabolic Syndrome; Rats | 2018 |
Inhibitory effects of azelnidipine tablets on morning hypertension.
Topics: Aged; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Dihydropyridines; Female; Humans; Hypertension; Male; Middle Aged; Registries; Tablets; Treatment Outcome | 2013 |
Study of sustained blood pressure-lowering effect of azelnidipine guided by self-measured morning and evening home blood pressure: subgroup analysis of the At-HOME study.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Dihydropyridines; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Time Factors; Treatment Outcome; Young Adult | 2013 |
Green asparagus (Asparagus officinalis) prevented hypertension by an inhibitory effect on angiotensin-converting enzyme activity in the kidney of spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Asparagus Plant; Azetidinecarboxylic Acid; Blood Pressure; Humans; Hypertension; Kidney; Male; Peptidyl-Dipeptidase A; Plant Preparations; Rats; Rats, Inbred SHR | 2013 |
Involvement of apoptosis inhibitor of macrophages in a rat hypertension model with nephrosclerosis: possible mechanisms of action of olmesartan and azelnidipine.
Topics: Animals; Antihypertensive Agents; Azetidinecarboxylic Acid; Calcium Channel Blockers; Chemokine CCL2; Dihydropyridines; Hypertension; Imidazoles; Inhibitor of Apoptosis Proteins; Kidney; Lipoproteins, LDL; Macrophages; Male; Nephrosclerosis; Olmesartan Medoxomil; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Scavenger; Tetrazoles | 2013 |
Discovering the sympathomodulatory properties of new calcium channel blockers: an exciting but still snaky journey.
Topics: Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Baroreflex; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Male; Sympathetic Nervous System | 2014 |
Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology.
Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Azetidinecarboxylic Acid; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Combinations; Drug Costs; Drug Substitution; Female; Humans; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Nephrology; Patient Satisfaction; Practice Patterns, Physicians'; Renal Insufficiency, Chronic; Retrospective Studies; Surveys and Questionnaires; Telmisartan; Tetrazoles; Valsartan | 2015 |
Regression of glomerular and tubulointerstitial injuries by dietary salt reduction with combination therapy of angiotensin II receptor blocker and calcium channel blocker in Dahl salt-sensitive rats.
Topics: Angiotensin Receptor Antagonists; Animals; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Combined Modality Therapy; Cytokines; Diet, Sodium-Restricted; Dihydropyridines; Drug Evaluation, Preclinical; Gene Expression; Gene Expression Regulation; Hypertension; Imidazoles; Kidney Glomerulus; Male; NADPH Oxidases; Rats, Inbred Dahl; Receptors, Mineralocorticoid; Renal Insufficiency; Tetrazoles | 2014 |
Medication-taking behavior in hypertensive patients with a single-tablet, fixed-dose combination in Japan.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Azetidinecarboxylic Acid; Cohort Studies; Dihydropyridines; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Japan; Male; Medication Adherence; Middle Aged; Prospective Studies; Surveys and Questionnaires; Tablets; Tetrazoles | 2016 |
Comparative effect of fixed-dose combination tablets of candesartan cilexetil/amlodipine versus olmesartan medoxomil/azelnidipine on laboratory parameters in patients with hypertension: a retrospective cohort study.
Topics: Aged; Alanine Transaminase; Amlodipine; Antihypertensive Agents; Aspartate Aminotransferases; Azetidinecarboxylic Acid; Benzimidazoles; Biphenyl Compounds; Blood Urea Nitrogen; Cohort Studies; Creatinine; Dihydropyridines; Drug Combinations; Female; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Olmesartan Medoxomil; Potassium; Propensity Score; Retrospective Studies; Sodium; Tetrazoles; Uric Acid | 2016 |
Effects of azelnidipine and amlodipine on exercise-induced sympathoexcitation assessed by pupillometry in hypertensive patients.
Topics: Amlodipine; Antihypertensive Agents; Autonomic Nervous System; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Essential Hypertension; Exercise; Female; Humans; Hypertension; Male; Middle Aged; Pupil | 2016 |
Olmesartan with azelnidipine versus with trichlormethiazide on home blood pressure variability in patients with type II diabetes mellitus.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Cross-Over Studies; Diabetes Mellitus, Type 2; Dihydropyridines; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Pilot Projects; Tetrazoles; Trichlormethiazide | 2017 |
Enhanced pulsatile pressure accelerates vascular smooth muscle migration: implications for atherogenesis of hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Calcium Signaling; Cell Movement; Cells, Cultured; Dihydropyridines; Disease Models, Animal; Equipment and Supplies; Estrenes; Hypertension; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Muscle, Smooth, Vascular; Oxazoles; Pyrrolidinones; Rats; Rats, Wistar; Signal Transduction; Tetrazoles; Type C Phospholipases | 2008 |
Renoprotective effect of azelnidipine in rats.
Topics: Animals; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Blood Urea Nitrogen; Calcium Channel Blockers; Collagen Type III; Data Interpretation, Statistical; Dihydropyridines; HSP47 Heat-Shock Proteins; Hypertension; Immunohistochemistry; Kidney; Kidney Diseases; Kidney Function Tests; Macrophages; Male; NADPH Oxidases; Phosphopyruvate Hydratase; Rats; Rats, Inbred SHR | 2008 |
Azelnidipine decreases sympathetic nerve activity via antioxidant effect in the rostral ventrolateral medulla of stroke-prone spontaneously hypertensive rats.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Antioxidants; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Disease Models, Animal; Heart Rate; Hydralazine; Hypertension; Male; Medulla Oblongata; NADPH Oxidases; Norepinephrine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stroke; Superoxide Dismutase; Sympathetic Nervous System; Thiobarbituric Acid Reactive Substances | 2008 |
Beneficial effect of combination therapy comprising angiotensin II receptor blocker plus calcium channel blocker on plasma adiponectin levels.
Topics: Adiponectin; Age Factors; Aged; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Benzimidazoles; Benzoates; Calcium Channel Blockers; Cohort Studies; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Sex Characteristics; Telmisartan | 2010 |
Plasma renin activity and aldosterone concentration are not altered by the novel calcium channel antagonist, azelnidipine, in hypertensive patients.
Topics: Aged; Aged, 80 and over; Aldosterone; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Renin | 2010 |
Anti-inflammatory properties of azelnidipine, a dihydropyridine-based calcium channel blocker.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Azetidinecarboxylic Acid; Biomarkers; C-Reactive Protein; Calcium Channel Blockers; Deoxyguanosine; Dihydropyridines; Female; Humans; Hypertension; In Vitro Techniques; Inflammation Mediators; Interleukin-6; Interleukin-8; Leukocytes, Mononuclear; Male; Middle Aged; Oxidative Stress | 2010 |
Intravascular ultrasound parameters in non-inferiority trial.
Topics: Amlodipine; Azetidinecarboxylic Acid; Coronary Artery Disease; Dihydropyridines; Humans; Hypertension | 2011 |
L-/T-type Ca channel blockers for kidney protection: ready for sophisticated use of Ca channel blockers.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dihydropyridines; Female; Humans; Hypertension; Imidazoles; Male; Tetrazoles | 2011 |
Combination therapy of olmesartan and azelnidipine inhibits sympathetic activity associated with reducing oxidative stress in the brain of hypertensive rats.
Topics: Animals; Antihypertensive Agents; Azetidinecarboxylic Acid; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Brain; Calcium Channel Blockers; Dihydropyridines; Disease Models, Animal; Drug Therapy, Combination; Hypertension; Imidazoles; Male; Olmesartan Medoxomil; Oxidative Stress; Rats; Rats, Inbred SHR; Tetrazoles | 2012 |
Calcium antagonist added to angiotensin receptor blocker: a recipe for reducing blood pressure variability?: evidence from day-by-day home blood pressure monitoring.
Topics: Azetidinecarboxylic Acid; Blood Pressure; Dihydropyridines; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Tetrazoles | 2012 |
A recipe for reducing blood pressure variability: adding blood flow to the mix.
Topics: Azetidinecarboxylic Acid; Blood Pressure; Dihydropyridines; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Tetrazoles | 2012 |
Hypertension in older adults: progress and limitations.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Imidazoles; Male; Tetrazoles | 2012 |
Combination therapy with an angiotensin-converting enzyme (ACE) inhibitor and a calcium antagonist: beyond the renoprotective effects of ACE inhibitor monotherapy in a spontaneous hypertensive rat with renal ablation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Drug Therapy, Combination; Hypertension; Kidney; Kidney Failure, Chronic; Male; Nephrectomy; Protective Agents; Rats; Rats, Inbred SHR; Thiazepines | 2002 |
Additive beneficial effects of the combination of a calcium channel blocker and an angiotensin blocker on a hypertensive rat-heart failure model.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Azetidinecarboxylic Acid; Calcium Channel Blockers; Cardiac Output, Low; Creatinine; Dihydropyridines; Drug Combinations; Echocardiography; Gene Expression; Hypertension; Imidazoles; Myocardium; Olmesartan Medoxomil; Organ Size; Rats; Rats, Inbred Dahl; Survival Analysis; Tetrazoles; Thiazepines | 2004 |
Unique atheroprotective property of azelnidipine, a dihydropyridine-based calcium antagonist.
Topics: Antihypertensive Agents; Antioxidants; Arteriosclerosis; Azetidinecarboxylic Acid; Biomarkers; Calcium; Cardiovascular Diseases; Cells, Cultured; Chemokine CCL2; Diabetes Mellitus; Dihydropyridines; Endothelium, Vascular; Humans; Hypertension; Insulin Resistance; Interleukin-8; Models, Biological; Reactive Oxygen Species; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; Umbilical Veins | 2005 |
Enhancement of cardiac oxidative stress by tachycardia and its critical role in cardiac hypertrophy and fibrosis.
Topics: Amlodipine; Animals; Azetidinecarboxylic Acid; Cardiomegaly; Dihydropyridines; Endomyocardial Fibrosis; Hydralazine; Hypertension; Male; Mitogen-Activated Protein Kinases; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tachycardia; Ventricular Remodeling | 2006 |
Azelnidipine down-regulates renal angiotensin-converting enzyme and mineralocorticoid receptor mRNA in diabetic hypertensive rats.
Topics: Animals; Aorta, Thoracic; Azetidinecarboxylic Acid; Blood Pressure; Body Weight; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Dihydropyridines; Down-Regulation; Heart; Hypertension; Kidney Cortex; Male; Myocardium; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Receptors, Mineralocorticoid; Renin-Angiotensin System; RNA, Messenger | 2006 |
Tilting-induced decrease in systolic blood pressure in bedridden hypertensive elderly inpatients: effects of azelnidipine.
Topics: Aged; Aged, 80 and over; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Inpatients; Male; Posture; Systole | 2006 |
Azelnidipine attenuates cardiovascular and sympathetic responses to air-jet stress in genetically hypertensive rats.
Topics: Administration, Oral; Animals; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Cardiovascular System; Dihydropyridines; Dose-Response Relationship, Drug; Heart Rate; Homeostasis; Hypertension; Injections, Intravenous; Male; Nicardipine; Rats; Rats, Inbred SHR; Stress, Physiological; Sympathetic Nervous System; Time Factors | 2007 |
Nicotianamine preferentially inhibits Angiotensin I-converting enzyme.
Topics: Alkaline Phosphatase; Angiotensin-Converting Enzyme Inhibitors; Animals; Azetidinecarboxylic Acid; Chelating Agents; Cobalt; Copper; Edetic Acid; Hypertension; Inhibitory Concentration 50; Leucyl Aminopeptidase; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Zinc | 2007 |
Clinical study with azelnidipine in patients with essential hypertension. Antiarteriosclerotic and cardiac hypertrophy-inhibitory effects and influence on autonomic nervous activity.
Topics: 3-Iodobenzylguanidine; Adipokines; Aged; Antihypertensive Agents; Antioxidants; Arteriosclerosis; Autonomic Nervous System; Azetidinecarboxylic Acid; Calcium Channel Blockers; Cardiomegaly; Carotid Arteries; Catecholamines; Cytokines; Dihydropyridines; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain; Pulse; Radionuclide Imaging; Radiopharmaceuticals | 2007 |
Effects of antihypertensive drugs and exercise training on insulin sensitivity in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Combined Modality Therapy; Dihydropyridines; Disease Models, Animal; Drug Therapy, Combination; Heart Rate; Hypertension; Imidazoles; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Regression Analysis; Sympathetic Nervous System; Tetrazoles | 2008 |
Effects of dihydropyridine Ca blockers on the renal function in nephrotic spontaneously hypertensive rat (SHR).
Topics: Animals; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Glomerular Filtration Rate; Heart Rate; Hypertension; Kidney Function Tests; Male; Nephrosis; Nicardipine; Puromycin Aminonucleoside; Rats; Rats, Inbred SHR; Sodium | 1994 |
Beneficial renal effects of CS-905, a novel dihydropyridine calcium blocker, in SHR.
Topics: Acetylglucosaminidase; Animals; Azetidinecarboxylic Acid; Azetines; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Hypertension; Kidney; Kidney Glomerulus; Male; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1989 |
Antihypertensive effects of CS-905, a novel dihydropyridine Ca++ channel blocker.
Topics: Anesthesia; Animals; Antihypertensive Agents; Aorta; Azetidinecarboxylic Acid; Azetines; Blood Pressure; Calcium Channel Blockers; Desoxycorticosterone; Dihydropyridines; Heart Rate; Hypertension; Hypertension, Renal; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nephrectomy; Rats; Rats, Inbred SHR; Rats, Inbred Strains | 1989 |