azepexole has been researched along with Heart Failure in 4 studies
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Heart failure is associated with increased sympathetic nerve activity." | 1.30 | Decreased responsiveness of vascular postjunctional alpha1-, alpha2-adrenoceptors and neuropeptide Y1 receptors in rats with heart failure. ( Edvinsson, L; Feng, Q; Hedner, T; Lu, X; Sun, X, 1999) |
| " The dose-response curves produced by phenylephrine in the two groups were comparable." | 1.29 | Forearm vascular responsiveness to alpha 1- and alpha 2-adrenoceptor stimulation in patients with congestive heart failure. ( Ceravolo, R; Chiariello, M; Condorelli, M; Esposito, G; Indolfi, C; Maione, A; Rapacciuolo, A; Rendina, V; Volpe, M, 1994) |
| " The dose-response curve in CHF was shifted to the right with a pD2 value of 5." | 1.29 | Vascular alpha-2 adrenoceptor function is decreased in rats with congestive heart failure. ( Bergdahl, A; Edvinsson, L; Feng, QP; Hedner, T; Lu, XR; Sun, XY, 1996) |
| "Prazosin had a 10-fold lower potency against epinephrine-induced contractions in the dorsal pedal artery, whereas it was not competitive against epinephrine in the saphenous vein." | 1.28 | Pacing-induced heart failure in the dog: evaluation of peripheral vascular alpha-adrenoceptor subtypes. ( Armstrong, PW; Forster, C, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Indolfi, C | 1 |
| Maione, A | 1 |
| Volpe, M | 1 |
| Rapacciuolo, A | 1 |
| Esposito, G | 1 |
| Ceravolo, R | 1 |
| Rendina, V | 1 |
| Condorelli, M | 1 |
| Chiariello, M | 1 |
| Feng, QP | 1 |
| Bergdahl, A | 1 |
| Lu, XR | 1 |
| Sun, XY | 1 |
| Edvinsson, L | 2 |
| Hedner, T | 2 |
| Feng, Q | 1 |
| Sun, X | 1 |
| Lu, X | 1 |
| Forster, C | 1 |
| Armstrong, PW | 1 |
4 other studies available for azepexole and Heart Failure
| Article | Year |
|---|---|
Forearm vascular responsiveness to alpha 1- and alpha 2-adrenoceptor stimulation in patients with congestive heart failure.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Azepines; Blood Vessels; Female; Forearm; Heart Failure; Hum | 1994 |
Vascular alpha-2 adrenoceptor function is decreased in rats with congestive heart failure.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Dose-Response | 1996 |
Decreased responsiveness of vascular postjunctional alpha1-, alpha2-adrenoceptors and neuropeptide Y1 receptors in rats with heart failure.
Topics: Adrenergic alpha-Agonists; Animals; Atrial Natriuretic Factor; Autonomic Fibers, Preganglionic; Azep | 1999 |
Pacing-induced heart failure in the dog: evaluation of peripheral vascular alpha-adrenoceptor subtypes.
Topics: Animals; Azepines; Blood Pressure; Cardiac Pacing, Artificial; Dogs; Dose-Response Relationship, Dru | 1990 |