Page last updated: 2024-10-23

azepexole and Heart Failure

azepexole has been researched along with Heart Failure in 4 studies

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Heart failure is associated with increased sympathetic nerve activity."1.30Decreased responsiveness of vascular postjunctional alpha1-, alpha2-adrenoceptors and neuropeptide Y1 receptors in rats with heart failure. ( Edvinsson, L; Feng, Q; Hedner, T; Lu, X; Sun, X, 1999)
" The dose-response curves produced by phenylephrine in the two groups were comparable."1.29Forearm vascular responsiveness to alpha 1- and alpha 2-adrenoceptor stimulation in patients with congestive heart failure. ( Ceravolo, R; Chiariello, M; Condorelli, M; Esposito, G; Indolfi, C; Maione, A; Rapacciuolo, A; Rendina, V; Volpe, M, 1994)
" The dose-response curve in CHF was shifted to the right with a pD2 value of 5."1.29Vascular alpha-2 adrenoceptor function is decreased in rats with congestive heart failure. ( Bergdahl, A; Edvinsson, L; Feng, QP; Hedner, T; Lu, XR; Sun, XY, 1996)
"Prazosin had a 10-fold lower potency against epinephrine-induced contractions in the dorsal pedal artery, whereas it was not competitive against epinephrine in the saphenous vein."1.28Pacing-induced heart failure in the dog: evaluation of peripheral vascular alpha-adrenoceptor subtypes. ( Armstrong, PW; Forster, C, 1990)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Indolfi, C1
Maione, A1
Volpe, M1
Rapacciuolo, A1
Esposito, G1
Ceravolo, R1
Rendina, V1
Condorelli, M1
Chiariello, M1
Feng, QP1
Bergdahl, A1
Lu, XR1
Sun, XY1
Edvinsson, L2
Hedner, T2
Feng, Q1
Sun, X1
Lu, X1
Forster, C1
Armstrong, PW1

Other Studies

4 other studies available for azepexole and Heart Failure

ArticleYear
Forearm vascular responsiveness to alpha 1- and alpha 2-adrenoceptor stimulation in patients with congestive heart failure.
    Circulation, 1994, Volume: 90, Issue:1

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Azepines; Blood Vessels; Female; Forearm; Heart Failure; Hum

1994
Vascular alpha-2 adrenoceptor function is decreased in rats with congestive heart failure.
    Cardiovascular research, 1996, Volume: 31, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Dose-Response

1996
Decreased responsiveness of vascular postjunctional alpha1-, alpha2-adrenoceptors and neuropeptide Y1 receptors in rats with heart failure.
    Acta physiologica Scandinavica, 1999, Volume: 166, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Atrial Natriuretic Factor; Autonomic Fibers, Preganglionic; Azep

1999
Pacing-induced heart failure in the dog: evaluation of peripheral vascular alpha-adrenoceptor subtypes.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:5

    Topics: Animals; Azepines; Blood Pressure; Cardiac Pacing, Artificial; Dogs; Dose-Response Relationship, Dru

1990