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azelastine and Mastocytosis

azelastine has been researched along with Mastocytosis in 2 studies

azelastine: azeptin is azelastine hydrochloride; structure; eye drop formulation effective in relieving symptoms of allergic conjunctivitis; do not confuse with 5-loxin which is an extract of Boswellia
azelastine : A phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position.

Mastocytosis: A rare neoplastic disorder characterized by a clonal proliferation of MAST CELLS, associated with KIT-D816 mutations, and accompanied by aberrant mast cell activation. The abnormal increase of MAST CELLS may occur in only the skin (MASTOCYTOSIS, CUTANEOUS), in extracutaneous tissues involving multiple organs (MASTOCYTOSIS, SYSTEMIC), or in solid tumors (MASTOCYTOMA).

Research Excerpts

ExcerptRelevanceReference
"It thus appears that azelastine is superior to chlorpheniramine in suppressing skin responses to histamine and morphine sulfate and in suppressing pruritus in patients with mastocytosis."9.07Comparison of azelastine and chlorpheniramine in the treatment of mastocytosis. ( Berkebile, C; Friedman, BS; Metcalfe, DD; Santiago, ML, 1993)
"It thus appears that azelastine is superior to chlorpheniramine in suppressing skin responses to histamine and morphine sulfate and in suppressing pruritus in patients with mastocytosis."5.07Comparison of azelastine and chlorpheniramine in the treatment of mastocytosis. ( Berkebile, C; Friedman, BS; Metcalfe, DD; Santiago, ML, 1993)
"Nonallergic rhinitis is a common disease that probably affects as many as 17 million Americans."2.41Update on nonallergic rhinitis. ( Lieberman, P; Settipane, RA, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Friedman, BS1
Santiago, ML1
Berkebile, C1
Metcalfe, DD1
Settipane, RA1
Lieberman, P1

Reviews

1 review available for azelastine and Mastocytosis

ArticleYear
Update on nonallergic rhinitis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2001, Volume: 86, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Age of Onset; Air Pollution; Anti-Inflammatory Agents, Non-Steroidal

2001

Trials

1 trial available for azelastine and Mastocytosis

ArticleYear
Comparison of azelastine and chlorpheniramine in the treatment of mastocytosis.
    The Journal of allergy and clinical immunology, 1993, Volume: 92, Issue:4

    Topics: Adult; Aged; Chlorpheniramine; Double-Blind Method; Drug Administration Schedule; Female; Histamine;

1993