azelastine has been researched along with Itching in 11 studies
azelastine: azeptin is azelastine hydrochloride; structure; eye drop formulation effective in relieving symptoms of allergic conjunctivitis; do not confuse with 5-loxin which is an extract of Boswellia
azelastine : A phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present data do not support the thesis that the increased plasma histamine concentration is causally related to pruritus in hemodialysis patients or that the antiallergic drug, azelastin HCL, alleviates the pruritus of dialysis patients by decreasing plasma histamine levels." | 9.07 | Effects of azelastin on pruritus and plasma histamine levels in hemodialysis patients. ( Hamada, M; Hasegawa, M; Ida, M; Matsui, C; Morohashi, M, 1994) |
| "Pruritus is a very common complication in chronic hemodialysis (HD) patients, however the exact mechanism for this affliction is still not known." | 5.29 | The effect of azelastin hydrochloride on pruritus and leukotriene B4 in hemodialysis patients. ( Fujimi, S; Fujishima, M; Hirakata, E; Hirakata, H; Kanai, H; Nagashima, A; Okuda, S, 1995) |
| "The present data do not support the thesis that the increased plasma histamine concentration is causally related to pruritus in hemodialysis patients or that the antiallergic drug, azelastin HCL, alleviates the pruritus of dialysis patients by decreasing plasma histamine levels." | 5.07 | Effects of azelastin on pruritus and plasma histamine levels in hemodialysis patients. ( Hamada, M; Hasegawa, M; Ida, M; Matsui, C; Morohashi, M, 1994) |
| "Azelastine was superior to cetirizine in reducing pruritus, whereas cetirizine caused a more marked reduction of whealing." | 2.69 | Differential effects of new-generation H1-receptor antagonists in pruritic dermatoses. ( Henz, BM; Metzenauer, P; O'Keefe, E; Zuberbier, T, 1998) |
| "Ginsenoside Re was orally administered to the mice treated with antibiotics (cefadroxil, oxytetracycline and erythromycin mixture (COE), streptomycin or/and tetracycline) and then investigated the relationship between ginsenoside Re-metabolizing β-glucosidase and α-rhamnosidase activities of intestinal microflora and its antiscratching behavioral effect." | 1.38 | Antibiotics attenuate anti-scratching behavioral effect of ginsenoside Re in mice. ( Han, MJ; Jang, SE; Joh, EH; Jung, IH; Kim, DH, 2012) |
| "Pruritus is a very common complication in chronic hemodialysis (HD) patients, however the exact mechanism for this affliction is still not known." | 1.29 | The effect of azelastin hydrochloride on pruritus and leukotriene B4 in hemodialysis patients. ( Fujimi, S; Fujishima, M; Hirakata, E; Hirakata, H; Kanai, H; Nagashima, A; Okuda, S, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ben-Eli, H | 1 |
| Solomon, A | 1 |
| Andoh, T | 4 |
| Zhang, Q | 1 |
| Yamamoto, T | 1 |
| Tayama, M | 1 |
| Hattori, M | 1 |
| Tanaka, K | 1 |
| Kuraishi, Y | 4 |
| Jang, SE | 1 |
| Jung, IH | 1 |
| Joh, EH | 1 |
| Han, MJ | 1 |
| Kim, DH | 2 |
| Ohtsuka, E | 1 |
| Kawai, S | 1 |
| Nojima, H | 1 |
| Kamimura, K | 1 |
| Yageta, Y | 1 |
| Takeshima, H | 1 |
| Shin, YW | 1 |
| Kanai, H | 1 |
| Nagashima, A | 1 |
| Hirakata, E | 1 |
| Hirakata, H | 1 |
| Okuda, S | 1 |
| Fujimi, S | 1 |
| Fujishima, M | 1 |
| Matsui, C | 1 |
| Ida, M | 1 |
| Hamada, M | 1 |
| Morohashi, M | 1 |
| Hasegawa, M | 1 |
| Henz, BM | 1 |
| Metzenauer, P | 1 |
| O'Keefe, E | 1 |
| Zuberbier, T | 1 |
| Horak, F | 1 |
| Berger, UE | 1 |
| Menapace, R | 1 |
| Toth, J | 1 |
| Stübner, PU | 1 |
| Marks, B | 1 |
1 review available for azelastine and Itching
| Article | Year |
|---|---|
Topical antihistamines, mast cell stabilizers, and dual-action agents in ocular allergy: current trends.
Topics: Administration, Ophthalmic; Anti-Allergic Agents; Benzazepines; Conjunctivitis, Allergic; Cromolyn S | 2018 |
3 trials available for azelastine and Itching
| Article | Year |
|---|---|
Effects of azelastin on pruritus and plasma histamine levels in hemodialysis patients.
Topics: Adult; Aged; Erythropoietin; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; | 1994 |
Differential effects of new-generation H1-receptor antagonists in pruritic dermatoses.
Topics: Adolescent; Adult; Aged; Cetirizine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; | 1998 |
Dose-dependent protection by azelastine eye drops against pollen-induced allergic conjunctivitis. A double-blind, placebo-controlled study.
Topics: Adult; Allergens; Anti-Allergic Agents; Conjunctivitis, Allergic; Cross-Over Studies; Dose-Response | 1998 |
7 other studies available for azelastine and Itching
| Article | Year |
|---|---|
Inhibitory effects of the methanol extract of Ganoderma lucidum on mosquito allergy-induced itch-associated responses in mice.
Topics: Animals; Antipruritics; Culicidae; Drugs, Chinese Herbal; Fruit; Histamine; Histamine H1 Antagonists | 2010 |
Antibiotics attenuate anti-scratching behavioral effect of ginsenoside Re in mice.
Topics: Adult; Aged; Animals; Anti-Allergic Agents; Anti-Bacterial Agents; Bacteria, Anaerobic; Behavior, An | 2012 |
Inhibitory effect of azelastine on allergic itch-associated response in mice sensitized with mosquito salivary glands extract.
Topics: Animals; Anti-Allergic Agents; Antipruritics; Calcium; Cells, Cultured; Culicidae; In Vitro Techniqu | 2003 |
Intradermal nociceptin elicits itch-associated responses through leukotriene B(4) in mice.
Topics: Animals; Anti-Allergic Agents; Dermatitis; Immunosuppressive Agents; Injections, Intradermal; Kerati | 2004 |
Antipruritic effect of ginsenoside rb1 and compound k in scratching behavior mouse models.
Topics: Animals; Antipruritics; Behavior, Animal; Capillary Permeability; Disease Models, Animal; Ginsenosid | 2005 |
The effect of azelastin hydrochloride on pruritus and leukotriene B4 in hemodialysis patients.
Topics: Histamine Antagonists; Histamine H1 Antagonists; Humans; Interleukin-6; Leukotriene B4; Phthalazines | 1995 |
Inhibitory effects of azelastine on substance P-induced itch-associated response in mice.
Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Calcium; Dinoprostone; Dose-Response Relationship, | 2002 |