Page last updated: 2024-10-23

azelastine and Disease Models, Animal

azelastine has been researched along with Disease Models, Animal in 13 studies

azelastine: azeptin is azelastine hydrochloride; structure; eye drop formulation effective in relieving symptoms of allergic conjunctivitis; do not confuse with 5-loxin which is an extract of Boswellia
azelastine : A phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"The influence of aerosolized azelastine on acute lung anaphylaxis in actively sensitized guinea pigs (experimental asthma model) was studied."7.67Inhibition of acute lung anaphylaxis by aerosolized azelastine in guinea pigs sensitized by three different procedures. ( Chand, N; Diamantis, W; Nolan, K; Sofia, RD, 1987)
"The influence of aerosolized azelastine on acute lung anaphylaxis in actively sensitized guinea pigs (experimental asthma model) was studied."3.67Inhibition of acute lung anaphylaxis by aerosolized azelastine in guinea pigs sensitized by three different procedures. ( Chand, N; Diamantis, W; Nolan, K; Sofia, RD, 1987)
"Azelastine has unique effects on dendritic cells and T cell interaction in vitro."1.40Unique immunomodulatory effects of azelastine on dendritic cells in vitro. ( Bäumer, W; Kietzmann, M; Schumacher, S; Stark, H, 2014)
"Respiratory and/or food allergy is common in children."1.35[Serous otitis media and allergy]. ( François, M, 2009)
"Middle ear effusion was observed in all OME animals that received 2 mg/kg AZ for 5 consecutive days, before and 3 days after the experimental OME was induced."1.30Efficacy of an antiallergic drug on otitis media with effusion in association with allergic rhinitis. An experimental study. ( Kawauchi, H; Kerakawauchi, H; Mogi, G; Suzuki, M, 1999)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's5 (38.46)18.2507
2000's4 (30.77)29.6817
2010's2 (15.38)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Zappia, CD1
Soto, A1
Granja-Galeano, G1
Fenoy, I1
Fernandez, N1
Davio, CA1
Shayo, C1
Fitzsimons, CP1
Goldman, A1
Monczor, F1
Schumacher, S1
Kietzmann, M1
Stark, H1
Bäumer, W1
François, M1
Satoh, T1
Sasaki, G1
Wu, MH1
Yokozeki, H1
Katayama, I1
Nishioka, K1
Shin, YW1
Kim, DH1
Sanchis-Merino, ME1
Montero, JA1
Ruiz-Moreno, JM1
Rodriguez, AE1
Pastor, S1
Leitch, IM1
Temple, DM1
Wei, H1
Boura, AL1
Konno, S1
Asano, K1
Gonokami, Y1
Kurokawa, M1
Kawazu, K1
Okamoto, K1
Adachi, M1
Chand, N2
Achterrath-Tuckermann, U1
Szelenyi, I1
Sofia, RD2
Nakagawa, N1
Obata, T1
Kobayashi, T1
Okada, Y1
Nambu, F1
Terawaki, T1
Furuya, T1
Muryobayashi, K1
Sawada, M1
Aishita, H1
Suzuki, M1
Kerakawauchi, H1
Kawauchi, H1
Mogi, G1
Nolan, K1
Diamantis, W1

Other Studies

13 other studies available for azelastine and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Azelastine potentiates antiasthmatic dexamethasone effect on a murine asthma model.
    Pharmacology research & perspectives, 2019, Volume: 7, Issue:6

    Topics: Administration, Intranasal; Animals; Anti-Asthmatic Agents; Asthma; Dexamethasone; Disease Models, A

2019
Unique immunomodulatory effects of azelastine on dendritic cells in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 2014, Volume: 387, Issue:11

    Topics: Animals; Anti-Allergic Agents; Cell Proliferation; Dendritic Cells; Dermatitis, Allergic Contact; Di

2014
[Serous otitis media and allergy].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2009, Volume: 16, Issue:1

    Topics: Administration, Oral; Allergens; Animals; Anti-Allergic Agents; Child; Child, Preschool; Clinical Tr

2009
Suplatast tosilate inhibits eosinophil production and recruitment into the skin in murine contact sensitivity.
    Clinical immunology (Orlando, Fla.), 2003, Volume: 108, Issue:3

    Topics: Administration, Oral; Animals; Anti-Allergic Agents; Arylsulfonates; Benzimidazoles; Cell Count; Der

2003
Antipruritic effect of ginsenoside rb1 and compound k in scratching behavior mouse models.
    Journal of pharmacological sciences, 2005, Volume: 99, Issue:1

    Topics: Animals; Antipruritics; Behavior, Animal; Capillary Permeability; Disease Models, Animal; Ginsenosid

2005
Comparative efficacy of topical antihistamines in an animal model of early phase allergic conjunctivitis.
    Experimental eye research, 2008, Volume: 86, Issue:5

    Topics: Animals; Anti-Allergic Agents; Benzimidazoles; Coloring Agents; Conjunctivitis, Allergic; Dibenzoxep

2008
Some anti-allergic and anti-inflammatory actions of 2-N-carboxamidinonormianserin (FCC5).
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:2

    Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drug

1995
Effect of azelastine on endotoxin-induced airway hyperresponsiveness in mice.
    International archives of allergy and immunology, 1995, Volume: 108, Issue:3

    Topics: Administration, Inhalation; Animals; Asthma; Bronchodilator Agents; Disease Models, Animal; Interleu

1995
Synergistic protective effects with azelastine and salbutamol in a guinea pig asthma model.
    Research communications in molecular pathology and pharmacology, 1995, Volume: 87, Issue:2

    Topics: Administration, Oral; Albuterol; Animals; Asthma; Bronchial Hyperreactivity; Bronchodilator Agents;

1995
Effect of a peptide leukotriene receptor antagonist, ONO-1078, on guinea-pig models of asthma.
    European journal of pharmacology, 1993, Apr-28, Volume: 235, Issue:2-3

    Topics: Acetylcholine; Acute-Phase Reaction; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstrict

1993
Efficacy of an antiallergic drug on otitis media with effusion in association with allergic rhinitis. An experimental study.
    The Annals of otology, rhinology, and laryngology, 1999, Volume: 108, Issue:6

    Topics: Animals; Disease Models, Animal; Drug Hypersensitivity; Guinea Pigs; Histamine H1 Antagonists; Male;

1999
Inhibition of acute lung anaphylaxis by aerosolized azelastine in guinea pigs sensitized by three different procedures.
    Annals of allergy, 1987, Volume: 58, Issue:5

    Topics: Aerosols; Anaphylaxis; Animals; Antigens; Asthma; Disease Models, Animal; Guinea Pigs; Injections, I

1987