azelastine has been researched along with Bronchial Hyperreactivity in 8 studies
azelastine: azeptin is azelastine hydrochloride; structure; eye drop formulation effective in relieving symptoms of allergic conjunctivitis; do not confuse with 5-loxin which is an extract of Boswellia
azelastine : A phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the efficacy of azelastine hydrochloride (azelastine, CAS 79307-93-0, Azeptin) in suppressing cough, 22 bronchial asthma patients complaining mainly of cough were given the drug for four weeks." | 9.08 | Antitussive effect of azelastine hydrochloride in patients with bronchial asthma. ( Ito, N; Kagaya, M; Kimura, K; Miura, M; Miura, S; Sano, M; Shindo, T; Shioya, T; Watanabe, A, 1998) |
| "To investigate the efficacy of azelastine hydrochloride (azelastine, CAS 79307-93-0, Azeptin) in suppressing cough, 22 bronchial asthma patients complaining mainly of cough were given the drug for four weeks." | 5.08 | Antitussive effect of azelastine hydrochloride in patients with bronchial asthma. ( Ito, N; Kagaya, M; Kimura, K; Miura, M; Miura, S; Sano, M; Shindo, T; Shioya, T; Watanabe, A, 1998) |
| "Azelastine significantly inhibited the development of the early asthmatic response." | 5.07 | The effect of H1-receptor blockade on the development of early- and late-phase bronchoconstriction and increased bronchial responsiveness in allergen-induced asthma. ( Holgate, ST; Ollier, S; Twentyman, OP, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Magnan, A | 1 |
| Tamaoki, J | 1 |
| Takemura, H | 1 |
| Tagaya, E | 1 |
| Sakai, A | 1 |
| Yamawaki, I | 1 |
| Konno, K | 1 |
| Chand, N | 1 |
| Achterrath-Tuckermann, U | 1 |
| Szelenyi, I | 1 |
| Sofia, RD | 1 |
| Arakawa, H | 1 |
| Andius, P | 1 |
| Kawikova, I | 1 |
| Skoogh, BE | 1 |
| Löfdahl, CG | 1 |
| Lötvall, J | 1 |
| Twentyman, OP | 1 |
| Ollier, S | 1 |
| Holgate, ST | 1 |
| Kanazawa, H | 1 |
| Kurihara, N | 1 |
| Hirata, K | 1 |
| Terakawa, K | 1 |
| Takeda, T | 1 |
| Shioya, T | 1 |
| Ito, N | 1 |
| Watanabe, A | 1 |
| Kagaya, M | 1 |
| Sano, M | 1 |
| Shindo, T | 1 |
| Miura, S | 1 |
| Kimura, K | 1 |
| Miura, M | 1 |
| Balzano, G | 1 |
| Gallo, C | 1 |
| Masi, C | 1 |
| Cocco, G | 1 |
| Ferranti, P | 1 |
| Melillo, E | 1 |
| Seccia, G | 1 |
3 trials available for azelastine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
The effect of H1-receptor blockade on the development of early- and late-phase bronchoconstriction and increased bronchial responsiveness in allergen-induced asthma.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Double-B | 1993 |
Antitussive effect of azelastine hydrochloride in patients with bronchial asthma.
Topics: Adolescent; Adult; Aged; Anti-Asthmatic Agents; Antitussive Agents; Asthma; Bronchial Hyperreactivit | 1998 |
Effect of azelastine on the seasonal increase in non-specific bronchial responsiveness to methacholine in pollen allergic patients. A randomized, double-blind placebo-controlled, crossover study.
Topics: Administration, Oral; Adolescent; Adult; Allergens; Asthma; Bronchial Hyperreactivity; Double-Blind | 1992 |
5 other studies available for azelastine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
[Respiratory allergies in the child and the adult].
Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Allergens; Anti-Allergic Ag | 2004 |
Effect of azelastine on airway hyperresponsiveness mediated by stimulated macrophages.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchial Hyperreactivi | 1995 |
Synergistic protective effects with azelastine and salbutamol in a guinea pig asthma model.
Topics: Administration, Oral; Albuterol; Animals; Asthma; Bronchial Hyperreactivity; Bronchodilator Agents; | 1995 |
Treatment with cyclosporin A during sensitization with trimellitic anhydride attenuates the airway responses to allergen challenge three weeks later.
Topics: Administration, Oral; Airway Resistance; Allergens; Animals; Betamethasone; Bronchial Hyperreactivit | 1994 |
Hyporesponsiveness to inhibitory agents of alveolar macrophages and polymorphonuclear leukocytes primed by platelet activating factor.
Topics: Adult; Aged; Asthma; Bronchial Hyperreactivity; Cells, Cultured; Dexamethasone; Female; Humans; Leuk | 1993 |