azelastine has been researched along with Atopic Hypersensitivity in 11 studies
azelastine: azeptin is azelastine hydrochloride; structure; eye drop formulation effective in relieving symptoms of allergic conjunctivitis; do not confuse with 5-loxin which is an extract of Boswellia
azelastine : A phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "4 mg azelastine administered orally on airway responsiveness, skin prick testing, daily peak expiratory flow rates and symptoms of asthma was compared with placebo in a 7 week double-blind, parallel group study of 24 patients with extrinsic asthma." | 9.06 | A study of the clinical efficacy of azelastine in patients with extrinsic asthma, and its effect on airway responsiveness. ( Aurich, R; Davies, RJ; Gould, CA; Ollier, S, 1988) |
| "4 mg azelastine administered orally on airway responsiveness, skin prick testing, daily peak expiratory flow rates and symptoms of asthma was compared with placebo in a 7 week double-blind, parallel group study of 24 patients with extrinsic asthma." | 5.06 | A study of the clinical efficacy of azelastine in patients with extrinsic asthma, and its effect on airway responsiveness. ( Aurich, R; Davies, RJ; Gould, CA; Ollier, S, 1988) |
| "The correlation between the antiasthma activity of azelastine and the concentrations of azelastine and its major metabolite, desmethylazelastine, in the blood and lung were investigated in guinea pigs." | 3.68 | Pharmacodynamic and pharmacokinetic studies with azelastine in the guinea pig: evidence for preferential distribution into the lung. ( Adusumalli, VE; Chand, N; Diamantis, W; Kucharczyk, N; Langevin, CN; Nolan, K; Pivonka, J; Sofia, RD; Wichmann, JK; Wong, KK, 1993) |
| "Treatment with azelastine (4 mg/os once daily) inhibited immediate reactions to allergens by 65% (range 55-74) and to histamine by 68% (range 47-82)." | 2.69 | Investigation of the anti-allergic activity of azelastine on the immediate and late-phase reactions to allergens and histamine using telethermography. ( Bähre, M; De Weck, AL; Derer, T, 2000) |
| "Azelastine is a powerful topical antihistamine, while budesonide appears to be a potent long-acting anti-inflammatory agent." | 2.68 | Effect of topical applications of budesonide and azelastine on nasal symptoms, eosinophil count and mediator release in atopic patients after nasal allergen challenge during the pollen season. ( Clement, P; De Waele, M; Smitz, J; Wang, D, 1997) |
| "The cough was relieved by inhaled procaterol in 10 patients (Group 2) but not in the other 10 patients (Group 1)." | 1.28 | Bronchodilator-resistive cough in atopic patients: bronchial reversibility and hyperresponsiveness. ( Fujimura, M; Matsuda, T; Sakamoto, S, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujimura, M | 2 |
| Magnan, A | 1 |
| Inoue, Y | 1 |
| Katayama, S | 1 |
| Akimoto, N | 1 |
| Shionoya, H | 1 |
| Morimoto, T | 1 |
| Katoh, Y | 1 |
| Chand, N | 1 |
| Adusumalli, VE | 1 |
| Nolan, K | 1 |
| Diamantis, W | 1 |
| Wichmann, JK | 1 |
| Pivonka, J | 1 |
| Langevin, CN | 1 |
| Wong, KK | 1 |
| Kucharczyk, N | 1 |
| Sofia, RD | 1 |
| Wang, D | 1 |
| Smitz, J | 1 |
| De Waele, M | 1 |
| Clement, P | 1 |
| Hanashiro, K | 1 |
| Tamaki, N | 1 |
| Koga, T | 1 |
| Nakamura, M | 1 |
| Kinjoh, K | 1 |
| Kosugi, T | 1 |
| De Weck, AL | 1 |
| Derer, T | 1 |
| Bähre, M | 1 |
| Shin, MH | 1 |
| Baroody, F | 1 |
| Proud, D | 1 |
| Kagey-Sobotka, A | 1 |
| Lichtenstein, LM | 1 |
| Naclerio, RM | 1 |
| Sakamoto, S | 1 |
| Matsuda, T | 1 |
| Gould, CA | 1 |
| Ollier, S | 1 |
| Aurich, R | 1 |
| Davies, RJ | 1 |
1 review available for azelastine and Atopic Hypersensitivity
| Article | Year |
|---|---|
[Causes of prolonged and chronic cough].
Topics: Adrenergic beta-Agonists; Albuterol; Androstadienes; Asthma; Chronic Disease; Clenbuterol; Cough; Dr | 2008 |
4 trials available for azelastine and Atopic Hypersensitivity
| Article | Year |
|---|---|
Effect of topical applications of budesonide and azelastine on nasal symptoms, eosinophil count and mediator release in atopic patients after nasal allergen challenge during the pollen season.
Topics: Adolescent; Adult; Allergens; Budesonide; Eosinophils; Female; Humans; Hypersensitivity, Immediate; | 1997 |
Investigation of the anti-allergic activity of azelastine on the immediate and late-phase reactions to allergens and histamine using telethermography.
Topics: Adult; Allergens; Alternaria; Anti-Allergic Agents; Asthma; Cross-Over Studies; Dermatitis, Atopic; | 2000 |
The effect of azelastine on the early allergic response.
Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine; Histamine H1 Antago | 1992 |
A study of the clinical efficacy of azelastine in patients with extrinsic asthma, and its effect on airway responsiveness.
Topics: Adult; Albuterol; Asthma; Bronchial Provocation Tests; Double-Blind Method; Female; Histamine H1 Ant | 1988 |
6 other studies available for azelastine and Atopic Hypersensitivity
| Article | Year |
|---|---|
[Respiratory allergies in the child and the adult].
Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Allergens; Anti-Allergic Ag | 2004 |
[Experimental study on an antihypersensitivity agent, 4-(p-chlorobenzyl)-2-[N-methyl-perhydroazepinyl-(4)]-1-(2H)-phthalazinone hydrochloride (azelastine)].
Topics: Animals; Female; Guinea Pigs; Histamine H1 Antagonists; Hypersensitivity, Immediate; In Vitro Techni | 1983 |
Anti-allergic effect of azelastine hydrochloride on immediate type hypersensitivity reactions in vivo and in vitro.
Topics: Animals; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Hypersensitivity, Immediate; In V | 1981 |
Pharmacodynamic and pharmacokinetic studies with azelastine in the guinea pig: evidence for preferential distribution into the lung.
Topics: Animals; Asthma; Guinea Pigs; Histamine H1 Antagonists; Hypersensitivity, Immediate; Lung; Phthalazi | 1993 |
Inhibitory effect of azelastine hydrochloride and suplatast tosilate on airway responses in sensitized rats following exposure to antigen.
Topics: Airway Resistance; Animals; Anti-Allergic Agents; Antigens; Arylsulfonates; Hypersensitivity, Delaye | 1997 |
Bronchodilator-resistive cough in atopic patients: bronchial reversibility and hyperresponsiveness.
Topics: Adrenergic beta-Agonists; Adult; Aged; Bronchi; Bronchodilator Agents; Cough; Drug Resistance; Ethan | 1992 |