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azelastine and Anaphylaxis

azelastine has been researched along with Anaphylaxis in 6 studies

azelastine: azeptin is azelastine hydrochloride; structure; eye drop formulation effective in relieving symptoms of allergic conjunctivitis; do not confuse with 5-loxin which is an extract of Boswellia
azelastine : A phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position.

Anaphylaxis: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.

Research Excerpts

ExcerptRelevanceReference
"The influence of aerosolized azelastine on acute lung anaphylaxis in actively sensitized guinea pigs (experimental asthma model) was studied."7.67Inhibition of acute lung anaphylaxis by aerosolized azelastine in guinea pigs sensitized by three different procedures. ( Chand, N; Diamantis, W; Nolan, K; Sofia, RD, 1987)
"Pretreatment with meclizine or terfenadine (15-30 mg/kg i."5.28Interference of azelastine with anaphylaxis induced by ovalbumin challenge in actively sensitized rats. ( Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Lima, MC; Martins, MA; Silva, AR; Silva, PM; Vargaftig, BB, 1992)
"Azelastine is an orally effective and long-acting inhibitor of in vivo synthesis and/or release of leukotrienes."5.27Inhibition of leukotriene (SRS-A)-mediated acute lung anaphylaxis by azelastine in guinea pigs. ( Chand, N; Diamantis, W; Nolan, K; Perhach, JL; Sofia, RD, 1986)
"The influence of aerosolized azelastine on acute lung anaphylaxis in actively sensitized guinea pigs (experimental asthma model) was studied."3.67Inhibition of acute lung anaphylaxis by aerosolized azelastine in guinea pigs sensitized by three different procedures. ( Chand, N; Diamantis, W; Nolan, K; Sofia, RD, 1987)
"Pretreatment with meclizine or terfenadine (15-30 mg/kg i."1.28Interference of azelastine with anaphylaxis induced by ovalbumin challenge in actively sensitized rats. ( Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Lima, MC; Martins, MA; Silva, AR; Silva, PM; Vargaftig, BB, 1992)
"Azelastine is an orally effective and long-acting inhibitor of in vivo synthesis and/or release of leukotrienes."1.27Inhibition of leukotriene (SRS-A)-mediated acute lung anaphylaxis by azelastine in guinea pigs. ( Chand, N; Diamantis, W; Nolan, K; Perhach, JL; Sofia, RD, 1986)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyauchi, H1
Horio, T1
Castro-Faria-Neto, HC1
Bozza, PT1
Silva, AR1
Silva, PM1
Lima, MC1
Martins, MA1
Cordeiro, RS1
Vargaftig, BB1
Chand, N4
Nolan, K3
Sofia, RD4
Diamantis, W4
Perhach, JL1

Other Studies

6 other studies available for azelastine and Anaphylaxis

ArticleYear
Detection of action, inhibition and augmentation spectra in solar urticaria.
    Dermatology (Basel, Switzerland), 1995, Volume: 191, Issue:4

    Topics: Anaphylaxis; Anti-Allergic Agents; Betamethasone; Cyclizine; Erythema; Female; Glucocorticoids; Hist

1995
Interference of azelastine with anaphylaxis induced by ovalbumin challenge in actively sensitized rats.
    European journal of pharmacology, 1992, Mar-24, Volume: 213, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Dihydropyridines; Dose-Response Relationship, Drug; Hematocrit; Hist

1992
Changes in aeroallergen-induced pulmonary mechanics in actively sensitized guinea pig: inhibition by azelastine.
    Annals of allergy, 1990, Volume: 64, Issue:2 Pt 1

    Topics: Air Pollution; Allergens; Anaphylaxis; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Hista

1990
Modulation of in vitro anaphylaxis of guinea-pig isolated tracheal segments by azelastine, inhibitors of arachidonic acid metabolism and selected antiallergic drugs.
    British journal of pharmacology, 1986, Volume: 87, Issue:2

    Topics: Airway Resistance; Anaphylaxis; Animals; Antigens; Arachidonic Acid; Arachidonic Acids; Guinea Pigs;

1986
Inhibition of leukotriene (SRS-A)-mediated acute lung anaphylaxis by azelastine in guinea pigs.
    Allergy, 1986, Volume: 41, Issue:7

    Topics: Anaphylaxis; Animals; Atropine; Chromones; Cromolyn Sodium; Guinea Pigs; Indomethacin; Ketotifen; Ma

1986
Inhibition of acute lung anaphylaxis by aerosolized azelastine in guinea pigs sensitized by three different procedures.
    Annals of allergy, 1987, Volume: 58, Issue:5

    Topics: Aerosols; Anaphylaxis; Animals; Antigens; Asthma; Disease Models, Animal; Guinea Pigs; Injections, I

1987