azelastine has been researched along with Allergic Reaction in 21 studies
azelastine: azeptin is azelastine hydrochloride; structure; eye drop formulation effective in relieving symptoms of allergic conjunctivitis; do not confuse with 5-loxin which is an extract of Boswellia
azelastine : A phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In guinea-pigs previously sensitized with ovalbumin, the intra-plantar administration of the antigen induced dose-dependent and sustained oedema." | 3.69 | Drug modulation of antigen-induced paw oedema in guinea-pigs: effects of lipopolysaccharide, tumour necrosis factor and leucocyte depletion. ( Cunha, FQ; da Motta, JI; Ferreira, SH; Vargaftig, BB, 1994) |
| "Vasomotor rhinitis is a common disorder that is seen routinely in allergy practice." | 2.46 | Vasomotor rhinitis. ( Lieberman, P; Pattanaik, D, 2010) |
| "The reference anti-allergy drugs, such as the inhaled corticosteroids or the cromones, without anti H1 activity, inhibit this late pulmonary response." | 2.38 | Pharmacological treatment of allergies. ( De Vos, C, 1992) |
| "Respiratory and/or food allergy is common in children." | 1.35 | [Serous otitis media and allergy]. ( François, M, 2009) |
| "Azelastine has previously been demonstrated to inhibit histamine release, to antagonize histamine-mediated responses, and to be a bronchodilator." | 1.28 | The interaction of azelastine with human lung histamine H1, beta, and muscarinic receptor-binding sites. ( Casale, TB, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (28.57) | 18.7374 |
| 1990's | 10 (47.62) | 18.2507 |
| 2000's | 2 (9.52) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| François, M | 1 |
| Pattanaik, D | 1 |
| Lieberman, P | 1 |
| Andoh, T | 1 |
| Zhang, Q | 1 |
| Yamamoto, T | 1 |
| Tayama, M | 1 |
| Hattori, M | 1 |
| Tanaka, K | 1 |
| Kuraishi, Y | 1 |
| Hide, I | 1 |
| Zechel, HJ | 1 |
| Brock, N | 1 |
| Lenke, D | 1 |
| Achterrath-Tuckermann, U | 1 |
| Arakawa, H | 1 |
| Andius, P | 1 |
| Kawikova, I | 1 |
| Skoogh, BE | 1 |
| Löfdahl, CG | 1 |
| Lötvall, J | 1 |
| Shiratori, Y | 1 |
| Takada, H | 1 |
| Hai, K | 1 |
| Kiriyama, H | 1 |
| Mawet, E | 1 |
| Komatsu, Y | 1 |
| Niwa, Y | 1 |
| Matsumura, M | 1 |
| Shiina, S | 1 |
| Kawase, T | 1 |
| da Motta, JI | 1 |
| Cunha, FQ | 1 |
| Vargaftig, BB | 1 |
| Ferreira, SH | 1 |
| Morita, M | 1 |
| Ohshima, Y | 1 |
| Akutagawa, H | 1 |
| Uenoyama, Y | 1 |
| Nambu, M | 1 |
| Mayumi, M | 1 |
| Mikawa, H | 1 |
| Nakagawa, N | 1 |
| Obata, T | 1 |
| Kobayashi, T | 1 |
| Okada, Y | 1 |
| Nambu, F | 1 |
| Terawaki, T | 1 |
| Furuya, T | 1 |
| Muryobayashi, K | 1 |
| Sawada, M | 1 |
| Aishita, H | 1 |
| Ventura, MT | 1 |
| Giuliano, G | 1 |
| Di Corato, R | 1 |
| Tursi, A | 1 |
| De Vos, C | 1 |
| Namimatsu, A | 1 |
| Go, K | 1 |
| Tanimoto, H | 1 |
| Okuda, M | 1 |
| Chand, N | 5 |
| Pillar, J | 3 |
| Diamantis, W | 5 |
| Sofia, RD | 5 |
| Nakagawa, T | 1 |
| Casale, TB | 1 |
| Harrison, JE | 1 |
| Rooney, SM | 1 |
3 reviews available for azelastine and Allergic Reaction
| Article | Year |
|---|---|
Vasomotor rhinitis.
Topics: Administration, Intranasal; Adrenal Cortex Hormones; Cholinergic Antagonists; Diagnosis, Differentia | 2010 |
[Mechanism of production and release of tumor necrosis factor implicated in inflammatory diseases].
Topics: Adenosine Triphosphate; Animals; Anti-Allergic Agents; Drug Design; Humans; Hypersensitivity; Inflam | 2003 |
Pharmacological treatment of allergies.
Topics: Animals; Cetirizine; Drug Evaluation; Drug Evaluation, Preclinical; Guinea Pigs; Histamine H1 Antago | 1992 |
18 other studies available for azelastine and Allergic Reaction
| Article | Year |
|---|---|
In Brief: OTC azelastine nasal spray 0.15% (Astepro Allergy) for allergic rhinitis.
Topics: Administration, Intranasal; Anti-Allergic Agents; Double-Blind Method; Histamine H1 Antagonists; Hum | 2022 |
In Brief: OTC azelastine nasal spray 0.15% (Astepro Allergy) for allergic rhinitis.
Topics: Administration, Intranasal; Anti-Allergic Agents; Double-Blind Method; Histamine H1 Antagonists; Hum | 2022 |
In Brief: OTC azelastine nasal spray 0.15% (Astepro Allergy) for allergic rhinitis.
Topics: Administration, Intranasal; Anti-Allergic Agents; Double-Blind Method; Histamine H1 Antagonists; Hum | 2022 |
In Brief: OTC azelastine nasal spray 0.15% (Astepro Allergy) for allergic rhinitis.
Topics: Administration, Intranasal; Anti-Allergic Agents; Double-Blind Method; Histamine H1 Antagonists; Hum | 2022 |
In Brief: OTC azelastine nasal spray 0.15% (Astepro Allergy) for allergic rhinitis.
Topics: Administration, Intranasal; Anti-Allergic Agents; Double-Blind Method; Histamine H1 Antagonists; Hum | 2022 |
In Brief: OTC azelastine nasal spray 0.15% (Astepro Allergy) for allergic rhinitis.
Topics: Administration, Intranasal; Anti-Allergic Agents; Double-Blind Method; Histamine H1 Antagonists; Hum | 2022 |
In Brief: OTC azelastine nasal spray 0.15% (Astepro Allergy) for allergic rhinitis.
Topics: Administration, Intranasal; Anti-Allergic Agents; Double-Blind Method; Histamine H1 Antagonists; Hum | 2022 |
In Brief: OTC azelastine nasal spray 0.15% (Astepro Allergy) for allergic rhinitis.
Topics: Administration, Intranasal; Anti-Allergic Agents; Double-Blind Method; Histamine H1 Antagonists; Hum | 2022 |
In Brief: OTC azelastine nasal spray 0.15% (Astepro Allergy) for allergic rhinitis.
Topics: Administration, Intranasal; Anti-Allergic Agents; Double-Blind Method; Histamine H1 Antagonists; Hum | 2022 |
[Serous otitis media and allergy].
Topics: Administration, Oral; Allergens; Animals; Anti-Allergic Agents; Child; Child, Preschool; Clinical Tr | 2009 |
Inhibitory effects of the methanol extract of Ganoderma lucidum on mosquito allergy-induced itch-associated responses in mice.
Topics: Animals; Antipruritics; Culicidae; Drugs, Chinese Herbal; Fruit; Histamine; Histamine H1 Antagonists | 2010 |
Pharmacological and toxicological properties of azelastine, a novel antiallergic agent.
Topics: Anesthetics, Local; Animals; Bronchi; Cats; Dogs; Female; Guinea Pigs; Hemodynamics; Histamine H1 An | 1981 |
Treatment with cyclosporin A during sensitization with trimellitic anhydride attenuates the airway responses to allergen challenge three weeks later.
Topics: Administration, Oral; Airway Resistance; Allergens; Animals; Betamethasone; Bronchial Hyperreactivit | 1994 |
Effect of anti-allergic agents on chemotaxis of neutrophils by stimulation of chemotactic factor released from hepatocytes exposed to ethanol.
Topics: Adult; Animals; Antibodies; Cells, Cultured; Chemokines; Chemotactic Factors; Chemotaxis, Leukocyte; | 1994 |
Drug modulation of antigen-induced paw oedema in guinea-pigs: effects of lipopolysaccharide, tumour necrosis factor and leucocyte depletion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Dexamethasone; Edema; Enzyme-Linke | 1994 |
Inhibitory effects of azelastine hydrochloride on Ca2+ influx, actin polymerization and release of eosinophil cationic protein of an eosinophilic leukaemia cell line EoL-1.
Topics: Actins; Blood Proteins; Bucladesine; Calcimycin; Calcium-Transporting ATPases; Cell Differentiation; | 1993 |
Effect of a peptide leukotriene receptor antagonist, ONO-1078, on guinea-pig models of asthma.
Topics: Acetylcholine; Acute-Phase Reaction; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstrict | 1993 |
Modulation of eosinophilic chemotaxis with azelastine and budesonide in allergic patients.
Topics: Adolescent; Adult; Anti-Allergic Agents; Budesonide; Calcium; Chemotaxis, Leukocyte; Cyclic AMP; Eos | 1998 |
Mechanism of nasal secretion mediated via nerve reflex in guinea pigs and evaluation of antiallergic drugs.
Topics: Allergens; Aminopyridines; Animals; Atropine Derivatives; Bronchodilator Agents; Capsaicin; Ganglion | 1992 |
Effect of azelastine on activation and release stages of allergic histamine secretion in rabbit basophils.
Topics: Animals; Basophils; Calcium; Histamine H1 Antagonists; Histamine Release; History, 20th Century; Hyp | 1991 |
[Chemical mediators and anti-mediator drugs].
Topics: Asthma; Chemotactic Factors, Eosinophil; Cromolyn Sodium; Cytokines; Depression, Chemical; Histamine | 1991 |
Inhibition of IgE-mediated allergic histamine release from rat peritoneal mast cells by azelastine and selected antiallergic drugs.
Topics: Animals; Astemizole; Benzimidazoles; Diphenhydramine; Histamine Release; Hypersensitivity; Immunoglo | 1985 |
Inhibition of allergic histamine release from rat peritoneal mast cells by azelastine. Interaction with selected antiasthmatic drugs.
Topics: Albuterol; Animals; Cromolyn Sodium; Drug Interactions; Histamine H1 Antagonists; Histamine Release; | 1988 |
The interaction of azelastine with human lung histamine H1, beta, and muscarinic receptor-binding sites.
Topics: Asthma; Binding, Competitive; Humans; Hypersensitivity; Lung; Phthalazines; Pyridazines; Receptors, | 1989 |
Modulation of in vitro anaphylaxis of guinea-pig isolated tracheal segments by azelastine, inhibitors of arachidonic acid metabolism and selected antiallergic drugs.
Topics: Airway Resistance; Anaphylaxis; Animals; Antigens; Arachidonic Acid; Arachidonic Acids; Guinea Pigs; | 1986 |
Inhibition of passive cutaneous anaphylaxis (PCA) by azelastine: dissociation of its antiallergic activities from antihistaminic and antiserotonin properties.
Topics: Animals; Antigens; Astemizole; Benzimidazoles; Histamine Antagonists; Hypersensitivity; Ketotifen; M | 1985 |