azelaic acid has been researched along with Cancer of Skin in 14 studies
nonanedioic acid : An alpha,omega-dicarboxylic acid that is heptane substituted at positions 1 and 7 by carboxy groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we investigated the antimelanogenic activity of combination of AZ and taurine (Tau) in B16F10 mouse melanoma cells." | 7.76 | Effect of combination of taurine and azelaic acid on antimelanogenesis in murine melanoma cells. ( Kim, AK; Yu, JS, 2010) |
| "Using a clonogenic assay in vitro, it has been shown that exposure to azelaic acid (1-100 mM) for 24 hours has a dose-dependent effect on the survival of the colony-forming ability of murine (B16) and human (HMB2, and SK23) melanoma cells as compared with a non-melanotic non-tumoral Chinese hamster cell line (CHO)." | 7.69 | Effect of azelaic acid on melanoma cells in culture. ( Breathnach, AS; Lemic-Stojcevic, L; Nias, AH, 1995) |
| "Azelaic acid, a linear C9 dicarbonic acid, can effect a reduction in the growth of melanoma cells." | 7.67 | [Effect of azelaic acid on the growth of melanoma cell cultures in comparison with fibroblast cultures]. ( Bauer, R; Geier, G; Hauschild, T; Kreysel, HW, 1986) |
| "In 23 patients with malignant melanoma, including some with metastases and terminal patients, topical and oral (10--15 g daily) azelaic acid given for 1--12 weeks before surgical excision of the lesions was followed by arrest and subsequent regression of the advancing edge of lesions, reduction in size and flattening of nodular areas, and progressive lightening of pigmentation." | 7.66 | Effect of azelaic acid on human malignant melanoma. ( Bernengo, A; Breathnach, A; Gallagher, S; Morpurgo, G; Nazzaro-Porro, M; Passi, S; Zina, G, 1980) |
| "Azelaic acid has been shown clinically to have a cytotoxic effect on the abnormally active and malignant human melanocyte, but it has no apparent effect upon normal melanocytes." | 5.27 | Ultrastructural observations on the effect of azelaic acid on normal human melanocytes and a human melanoma cell line in tissue culture. ( Bennett, D; Bhasin, Y; Breathnach, AS; Ethridge, L; Nazzaro-Porro, M; Passi, S; Picardo, M; Robins, EJ; Ward, BJ, 1985) |
| " In this study, we investigated the antimelanogenic activity of combination of AZ and taurine (Tau) in B16F10 mouse melanoma cells." | 3.76 | Effect of combination of taurine and azelaic acid on antimelanogenesis in murine melanoma cells. ( Kim, AK; Yu, JS, 2010) |
| "Using a clonogenic assay in vitro, it has been shown that exposure to azelaic acid (1-100 mM) for 24 hours has a dose-dependent effect on the survival of the colony-forming ability of murine (B16) and human (HMB2, and SK23) melanoma cells as compared with a non-melanotic non-tumoral Chinese hamster cell line (CHO)." | 3.69 | Effect of azelaic acid on melanoma cells in culture. ( Breathnach, AS; Lemic-Stojcevic, L; Nias, AH, 1995) |
| "Azelaic acid, a linear C9 dicarbonic acid, can effect a reduction in the growth of melanoma cells." | 3.67 | [Effect of azelaic acid on the growth of melanoma cell cultures in comparison with fibroblast cultures]. ( Bauer, R; Geier, G; Hauschild, T; Kreysel, HW, 1986) |
| "In 23 patients with malignant melanoma, including some with metastases and terminal patients, topical and oral (10--15 g daily) azelaic acid given for 1--12 weeks before surgical excision of the lesions was followed by arrest and subsequent regression of the advancing edge of lesions, reduction in size and flattening of nodular areas, and progressive lightening of pigmentation." | 3.66 | Effect of azelaic acid on human malignant melanoma. ( Bernengo, A; Breathnach, A; Gallagher, S; Morpurgo, G; Nazzaro-Porro, M; Passi, S; Zina, G, 1980) |
| "Azelaic acid is a complex molecule with many diverse activities." | 2.52 | Azelaic Acid: Evidence-based Update on Mechanism of Action and Clinical Application. ( Rosen, T; Schulte, BC; Wu, W, 2015) |
| "Amelanotic lentigo maligna melanoma (ALMM) is an infrequent presentation of lentigo maligna melanoma, less than thirty cases having been reported to date." | 2.40 | Amelanotic lentigo maligna melanoma: report of a case and review of the literature. ( de Moragas, JM; Puig, L; Rocamora, V; Romaní, J, 1999) |
| "Azelaic acid is a naturally occurring straight-chained 9-carbon atom dicarboxylic acid which is non-toxic, non-teratogenic, and non-mutagenic." | 1.30 | Azelaic acid: potential as a general antitumoural agent. ( Breathnach, AS, 1999) |
| "Azelaic acid has been shown clinically to have a cytotoxic effect on the abnormally active and malignant human melanocyte, but it has no apparent effect upon normal melanocytes." | 1.27 | Ultrastructural observations on the effect of azelaic acid on normal human melanocytes and a human melanoma cell line in tissue culture. ( Bennett, D; Bhasin, Y; Breathnach, AS; Ethridge, L; Nazzaro-Porro, M; Passi, S; Picardo, M; Robins, EJ; Ward, BJ, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Quigley, EA | 1 |
| Halpern, AC | 1 |
| Schulte, BC | 1 |
| Wu, W | 1 |
| Rosen, T | 1 |
| Yu, JS | 1 |
| Kim, AK | 1 |
| Nazzaro-Porro, M | 4 |
| Passi, S | 3 |
| Zina, G | 1 |
| Bernengo, A | 1 |
| Breathnach, A | 1 |
| Gallagher, S | 1 |
| Morpurgo, G | 1 |
| Lemic-Stojcevic, L | 1 |
| Nias, AH | 1 |
| Breathnach, AS | 4 |
| Rodríguez Prieto, MA | 1 |
| Manchado Lopez, P | 1 |
| Ruiz Gonzalez, I | 1 |
| Suarez, D | 1 |
| Balus, L | 1 |
| Picardo, M | 2 |
| Potenza, C | 1 |
| Rocamora, V | 1 |
| Puig, L | 1 |
| Romaní, J | 1 |
| de Moragas, JM | 1 |
| Sowden, J | 1 |
| Paramsothy, Y | 1 |
| Smith, AG | 1 |
| Geier, G | 1 |
| Hauschild, T | 1 |
| Bauer, R | 1 |
| Kreysel, HW | 1 |
| McLean, DI | 1 |
| Peter, KK | 1 |
| Robins, EJ | 1 |
| Bennett, D | 1 |
| Ward, BJ | 1 |
| Bhasin, Y | 1 |
| Ethridge, L | 1 |
4 reviews available for azelaic acid and Cancer of Skin
| Article | Year |
|---|---|
Microinvasive melanoma: cutaneous pharmacotherapeutic approaches.
Topics: Aged; Aged, 80 and over; Aminoquinolines; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Ne | 2013 |
Azelaic Acid: Evidence-based Update on Mechanism of Action and Clinical Application.
Topics: Acne Vulgaris; Alopecia Areata; Dermatitis, Perioral; Dermatologic Agents; Dicarboxylic Acids; Facia | 2015 |
Amelanotic lentigo maligna melanoma: report of a case and review of the literature.
Topics: Aged; Antineoplastic Agents; Combined Modality Therapy; Cryotherapy; Dicarboxylic Acids; Female; Flu | 1999 |
Azelaic acid.
Topics: Acne Vulgaris; Antineoplastic Agents; Dicarboxylic Acids; Humans; Skin Diseases; Skin Neoplasms | 1987 |
10 other studies available for azelaic acid and Cancer of Skin
| Article | Year |
|---|---|
Effect of combination of taurine and azelaic acid on antimelanogenesis in murine melanoma cells.
Topics: Animals; Cell Line, Tumor; Dicarboxylic Acids; Drug Combinations; Humans; Melanins; Melanocytes; Mel | 2010 |
Effect of azelaic acid on human malignant melanoma.
Topics: Administration, Oral; Administration, Topical; Dicarboxylic Acids; Follow-Up Studies; Humans; Melano | 1980 |
Effect of azelaic acid on melanoma cells in culture.
Topics: Animals; Antineoplastic Agents; Cell Division; CHO Cells; Cricetinae; Dicarboxylic Acids; Humans; Me | 1995 |
Treatment of lentigo maligna with azelaic acid.
Topics: Aged; Dermatologic Agents; Dicarboxylic Acids; Female; Humans; Lentigo; Male; Melanoma; Skin Neoplas | 1993 |
A case of recurrent (following surgery x2) invasive malignant melanoma with satellitosis (stage IIIA) successfully resolving after azelaic acid treatment administered by several routes.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Dicarboxylic Acids; Female; Humans; Melanoma; Neopla | 1996 |
Azelaic acid: potential as a general antitumoural agent.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Squamous Cell; Dicarboxylic Acids; Fema | 1999 |
Malignant melanoma arising in the scar of lupus vulgaris and response to treatment with topical azelaic acid.
Topics: Administration, Topical; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cicatrix; Dicarboxyl | 1988 |
[Effect of azelaic acid on the growth of melanoma cell cultures in comparison with fibroblast cultures].
Topics: Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Dicarboxylic Acids; Dose-Response Re | 1986 |
Apparent progression of lentigo maligna to invasive melanoma during treatment with topical azelaic acid.
Topics: Aged; Dicarboxylic Acids; Female; Humans; Melanoma; Middle Aged; Neoplasm Invasiveness; Nevus, Pigme | 1986 |
Ultrastructural observations on the effect of azelaic acid on normal human melanocytes and a human melanoma cell line in tissue culture.
Topics: Cell Line; Cells, Cultured; Dicarboxylic Acids; Epidermis; Humans; Infant, Newborn; Melanocytes; Mel | 1985 |