azd4547 and Urinary-Bladder-Neoplasms

azd4547 has been researched along with Urinary-Bladder-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for azd4547 and Urinary-Bladder-Neoplasms

Article	Year
Synthesis of novel arylaminoquinazolinylurea derivatives and their antiproliferative activities against bladder cancer cell line. Bioorganic & medicinal chemistry letters, 2016, 10-15, Volume: 26, Issue:20 A novel series of arylurea and arylamide derivatives 1a-z, 2a-d having aminoquinazoline scaffold was designed and synthesized. Their in vitro antiproliferative activities against RT112 bladder cancer cell line and inhibitory activities against FGFR3 kinase were tested. Most compounds showed good antiproliferative activities against RT112 bladder cancer cell line, and arylurea compounds 1a-z were more potent than arylamide compounds 2a-d. Among them, eight compounds 1a, 1d-g, 1l, 1y, and 1z showed potent activities with GI Topics: Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Quinazolines; Urea; Urinary Bladder Neoplasms	2016

Article

Year

Synthesis of novel arylaminoquinazolinylurea derivatives and their antiproliferative activities against bladder cancer cell line.

Bioorganic & medicinal chemistry letters, 2016, 10-15, Volume: 26, Issue:20

A novel series of arylurea and arylamide derivatives 1a-z, 2a-d having aminoquinazoline scaffold was designed and synthesized. Their in vitro antiproliferative activities against RT112 bladder cancer cell line and inhibitory activities against FGFR3 kinase were tested. Most compounds showed good antiproliferative activities against RT112 bladder cancer cell line, and arylurea compounds 1a-z were more potent than arylamide compounds 2a-d. Among them, eight compounds 1a, 1d-g, 1l, 1y, and 1z showed potent activities with GI

Topics: Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Quinazolines; Urea; Urinary Bladder Neoplasms

2016