azd3965 and Stomach-Neoplasms

azd3965 has been researched along with Stomach-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for azd3965 and Stomach-Neoplasms

Article	Year
MACC1 mediates chemotherapy sensitivity of 5-FU and cisplatin via regulating MCT1 expression in gastric cancer. Biochemical and biophysical research communications, 2017, 04-08, Volume: 485, Issue:3 Chemotherapeutic insensitivity is a main obstacle for effective treatment of gastric cancer (GC), the underlying mechanism remains to be investigated. Metastasis-associated in colon cancer-1 (MACC1), a transcription factor highly expressed in GC, is found to be related to chemotherapy sensitivity. Monocarboxylate transporter 1 (MCT1), a plasma membrane protein co-transporting lactate and H Topics: Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Survival; Cisplatin; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Monocarboxylic Acid Transporters; Multivariate Analysis; Prognosis; Pyrimidinones; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Stomach Neoplasms; Symporters; Thiophenes; Trans-Activators; Transcription Factors	2017

Article

Year

MACC1 mediates chemotherapy sensitivity of 5-FU and cisplatin via regulating MCT1 expression in gastric cancer.

Biochemical and biophysical research communications, 2017, 04-08, Volume: 485, Issue:3

Chemotherapeutic insensitivity is a main obstacle for effective treatment of gastric cancer (GC), the underlying mechanism remains to be investigated. Metastasis-associated in colon cancer-1 (MACC1), a transcription factor highly expressed in GC, is found to be related to chemotherapy sensitivity. Monocarboxylate transporter 1 (MCT1), a plasma membrane protein co-transporting lactate and H

Topics: Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Survival; Cisplatin; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Monocarboxylic Acid Transporters; Multivariate Analysis; Prognosis; Pyrimidinones; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Stomach Neoplasms; Symporters; Thiophenes; Trans-Activators; Transcription Factors

2017