azauridine has been researched along with Purine Pyrimidine Metabolism, Inborn Errors in 4 studies
Azauridine: A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Orotic aciduria is a rare autosomal recessive disease in man due to a deficiency of orotate phosphoribosyltransferase (EC 2." | 1.25 | Hereditary orotic aciduria: evidence for a structural gene mutation. ( Grobner, W; Kelley, WN; Worthy, TE, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FALLON, HJ | 1 |
| FREI, E | 1 |
| BLOCK, J | 1 |
| SEEGMILLER, JE | 1 |
| Gröbner, W | 2 |
| Zöllner, N | 1 |
| Perry, ME | 1 |
| Jones, ME | 1 |
| Worthy, TE | 1 |
| Kelley, WN | 1 |
1 review available for azauridine and Purine Pyrimidine Metabolism, Inborn Errors
| Article | Year |
|---|---|
[Disorders of human pyrimidine metabolism (author's transl)].
Topics: Allopurinol; Azauridine; Chemical Phenomena; Chemistry; Cytidine; Folic Acid; Humans; Infant; Male; | 1975 |
3 other studies available for azauridine and Purine Pyrimidine Metabolism, Inborn Errors
| Article | Year |
|---|---|
The uricosuria and orotic aciduria induced by 6-azauridine.
Topics: Antineoplastic Agents; Azauridine; Humans; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine | 1961 |
Orotic aciduria fibroblasts express a labile form of UMP synthase.
Topics: Azauridine; Carboxy-Lyases; Cell Division; Cell Line; Cells, Cultured; Fibroblasts; Humans; Kinetics | 1989 |
Hereditary orotic aciduria: evidence for a structural gene mutation.
Topics: Azauridine; Carbon Radioisotopes; Carboxy-Lyases; Cells, Cultured; Centrifugation, Density Gradient; | 1974 |