azauridine has been researched along with Pregnancy in 15 studies
Azauridine: A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The reproductive performance of 36 women who had been successfully treated for gestational trophoblastic tumors with multiple courses of cytotoxic agents including methotrexate, 6-mercaptopurine, actinomycin D, and 6-azauridine, between 1962 and 1972, has been studied in comparison with 36 patients who had spontaneously aborted a hydatidiform mole but received no treatment and a control group consisting of 36 women attending an antenatal clinic." | 3.65 | Reproductive performance of women successfully treated for gestational trophoblastic tumors. ( Bagshawe, KD; Walden, PA, 1976) |
| " Considering the sensitivity peaks of the morphogenetic processes which were observed, the dose-response relationships, the transformation of the teratogenic to a lethal effect and critical period extension with increasing doses, it was found that the effects of ia and im administered 6-azauridine did not differ." | 1.26 | Embryotoxicity of transplacentally and intraamniotically administered 6-azauridine in mice. ( Dostál, M; Jelínek, R, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bílá, V | 2 |
| Kren, V | 2 |
| Bhasin, S | 1 |
| Shambaugh, GE | 1 |
| Walden, PA | 1 |
| Bagshawe, KD | 1 |
| Dostál, M | 2 |
| Jelínek, R | 5 |
| Seifertová, M | 2 |
| Tykva, R | 1 |
| Cihák, A | 1 |
| Veselý, J | 1 |
| Chaudhuri, G | 1 |
| Roy, S | 1 |
| Das, R | 1 |
| Arora, RB | 1 |
| Shepard, TH | 1 |
| O'Sullivan, WJ | 1 |
| Rychter, Z | 2 |
| van Wagenen, G | 1 |
| DeConti, RC | 1 |
| Handschumacher, RE | 1 |
| Wade, ME | 1 |
1 review available for azauridine and Pregnancy
| Article | Year |
|---|---|
Orotic acid.
Topics: Allopurinol; Anemia, Pernicious; Animals; Azauridine; Carboxy-Lyases; Fatty Liver; Female; Humans; I | 1973 |
1 trial available for azauridine and Pregnancy
| Article | Year |
|---|---|
Azaribine (Triazure) for severe psoriasis.
Topics: Antimetabolites; Azauridine; Child; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Metho | 1976 |
13 other studies available for azauridine and Pregnancy
| Article | Year |
|---|---|
The analysis of the interaction of PLS determining gene 1x and its modifiers with teratogens.
Topics: Animals; Azauridine; Bromodeoxyuridine; Dose-Response Relationship, Drug; Epistasis, Genetic; Female | 1980 |
Fetal fuels. V. Ketone bodies inhibit pyrimidine biosynthesis in fetal rat brain.
Topics: Animals; Azauridine; Brain; Female; Fetus; Glutamine; Hydroxybutyrates; Ketone Bodies; Organ Size; P | 1982 |
Reproductive performance of women successfully treated for gestational trophoblastic tumors.
Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Azauridine; Child; Child, Preschool; Dactinomyci | 1976 |
Embryotoxicity of transplacentally and intraamniotically administered 6-azauridine in mice.
Topics: Abnormalities, Drug-Induced; Amnion; Animals; Azauridine; Cleft Lip; Cleft Palate; Embryo, Mammalian | 1979 |
Mutant gene--teratogen interaction studied on different genetic backgrounds.
Topics: Abnormalities, Drug-Induced; Alleles; Animals; Azauridine; Crosses, Genetic; Female; Genotype; Heter | 1978 |
Varying distribution of 6-azauridine within the mouse foetoplacental unit.
Topics: Amniotic Fluid; Animals; Azauridine; Female; Fetus; Maternal-Fetal Exchange; Mice; Placenta; Pregnan | 1977 |
Effect of 5-azacytidine and 6-azauridine on the synthesis of DNA in embryonic mouse brain mitotic activity and migration of ventricular cells.
Topics: Animals; Autoradiography; Azacitidine; Azauridine; Brain; Cell Movement; Cerebral Ventricles; Cytidi | 1973 |
Interruption of pregnancy in rats by 6-azauridine.
Topics: Abortion, Spontaneous; Animals; Azauridine; Female; Fetal Resorption; Pregnancy; Pregnancy, Animal; | 1974 |
Teratogenicity from drugs--an increasing problem.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Aminopterin; Amniocentesis; Animals; Anti-Bact | 1974 |
Change in shape and location of non-vascularized area of ventricular myocardium in chick embryo during terminal phase of heart vascularization after administration of 6-azauridine in different doses.
Topics: Animals; Azauridine; Chick Embryo; Coronary Vessels; Female; Heart; Heart Ventricles; Pregnancy | 1973 |
Morphogenesis of cleft palate induced by exogenous factors. VI. The question of delayed palatal-process horizontalization.
Topics: Animals; Azauridine; Cleft Palate; Cortisone; Female; Fetus; Gestational Age; Mice; Morphogenesis; O | 1974 |
Abortifacient and teratogenic effects of triacetyl-6-azauridine in the monkey.
Topics: Abnormalities, Drug-Induced; Abortifacient Agents; Animals; Antimetabolites; Azauridine; Contracepti | 1970 |
[Method for evaluation of the effect of teratogenic agents (6-azauridine) on late development stages].
Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Azauridine; Chick Embryo; Embryonic and Fetal | 1971 |