azauridine has been researched along with Neoplasms in 15 studies
Azauridine: A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These results also reveal that anticancer drugs other than amino acid analogs and amino acid-depleting enzymes may cause significant changes in amino acid metabolism." | 1.26 | Changes in amino acid metabolism caused by 6-azauridine triacetate: relevance to cancer treatment. ( Slavik, M, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (93.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, YE | 1 |
| Park, R | 1 |
| Jang, M | 1 |
| Park, YI | 1 |
| Yamamoto, A | 1 |
| Oh, WK | 1 |
| Lee, EJ | 1 |
| Park, J | 1 |
| KAFKA, V | 2 |
| MUSIL, J | 1 |
| PADOVEC, J | 1 |
| SORM, F | 5 |
| BRUEMMER, NC | 1 |
| HOLLAND, JF | 1 |
| SHEEHE, PR | 1 |
| KARA, J | 2 |
| WINKLER, A | 4 |
| DRAHOVSKY, D | 2 |
| GREGUSOVA, V | 3 |
| THURZO, V | 1 |
| SKODA, J | 3 |
| HUPKA, S | 2 |
| KRATOCHVIL, M | 1 |
| CREASEY, WA | 1 |
| FINK, ME | 1 |
| HANDSCHUMACHER, RE | 2 |
| CALABRESI, P | 2 |
| PRUSOFF, WH | 1 |
| SKUPENOVA, A | 1 |
| MUSIL, I | 1 |
| GAEK, A | 1 |
| NOVOTNY, A | 1 |
| PADOVETS, I | 1 |
| PAVLOEVKA, I | 1 |
| PASTERNAK, CA | 1 |
| Slavik, M | 1 |
| Bergstresser, PR | 1 |
| Schreiber, SH | 1 |
| Weinstein, GD | 1 |
| Bergevin, PR | 1 |
| Tormey, DC | 1 |
| Blom, J | 1 |
3 reviews available for azauridine and Neoplasms
| Article | Year |
|---|---|
A REVIEW OF SOME ASPECTS OF 5-IODODEOXYURIDINE AND AZAURIDINE.
Topics: Azauridine; Idoxuridine; Metabolism; Neoplasms; Nucleosides; Pharmacology | 1963 |
CURRENT STATUS OF CLINICAL INVESTIGATIONS WITH 6-AZAURIDINE, 5-IODO-2'-DEOXYURIDINE, AND RELATED DERIVATIVES.
Topics: Antineoplastic Agents; Azauridine; Humans; Idoxuridine; Neoplasms; Nucleosides | 1963 |
Guide to the use of cancer chemotherapeutic agents.
Topics: Alkylating Agents; Allopurinol; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; | 1972 |
12 other studies available for azauridine and Neoplasms
| Article | Year |
|---|---|
6-Azauridine Induces Autophagy-Mediated Cell Death via a p53- and AMPK-Dependent Pathway.
Topics: AMP-Activated Protein Kinase Kinases; Antineoplastic Agents; Apoptosis; Autophagic Cell Death; Autop | 2021 |
[Chemotherapy of malignant tumors in gynecology; a report on therapy with azauridine (6-azauracilriboside)].
Topics: Antineoplastic Agents; Azauridine; Gynecology; Neoplasms; Nucleosides; Nucleotides | 1961 |
Drug effects on a target metabolic pathway and on mouse tumor growth: azauridine and decarboxylation of orotic acid-7-C-14.
Topics: Animals; Azauridine; Decarboxylation; Metabolic Networks and Pathways; Mice; Neoplasms; Neoplasms, E | 1962 |
Determination of uridine kinase activity in some human tumours and normal tissues, using 4,5-14-C-6-azauridine as substrate.
Topics: Antineoplastic Agents; Azauridine; Humans; Neoplasms; Nucleosides; Phosphorylation; Phosphotransfera | 1963 |
Determination of uridine kinase activity in some human tumours and in leucaemic cells using 4,5-C-14--azauridine as substrate.
Topics: Azauridine; Humans; Leukemia; Neoplasms; Nucleosides; Nucleotides; Phosphotransferases; Uridine Kina | 1962 |
The distribution of 6-azauridine in the organs and tumours in man.
Topics: Azauridine; Biochemical Phenomena; Neoplasms; Nucleosides; Nucleotides | 1962 |
Clinical and pharmacological studies with 2',3',5'-triacetyl-6-azauridine.
Topics: Azauridine; Neoplasms; Nucleosides; Research | 1963 |
THE SENSITIVITY OF HUMAN LEUKAEMIAS TO 6-AZAURIDINE AND ITS RELATION TO URIDINE-KINASE ACTIVITY.
Topics: Antineoplastic Agents; Azauridine; Carboxy-Lyases; Enzyme Inhibitors; Humans; Leukemia; Leukemia, My | 1964 |
[STUDY OF THE EFFECTIVENESS OF DIFFERENT DOSES OF 6-AZAURIDINE IN MALIGNANT TUMORS OF THE FEMALE GENITALIA].
Topics: Antineoplastic Agents; Azauridine; Blood Chemical Analysis; Female; Genital Neoplasms, Female; Genit | 1964 |
The biochemical activity of 6-azauridine: interference with pyrimidine metabolism in transplantable mouse tumors.
Topics: Animals; Azauridine; Mice; Neoplasm Transplantation; Neoplasms; Nucleosides; Nucleotides; Pyrimidine | 1959 |
Changes in amino acid metabolism caused by 6-azauridine triacetate: relevance to cancer treatment.
Topics: Amino Acids; Animals; Azauridine; Humans; Neoplasms; Rabbits; Thromboembolism | 1979 |
Systemic chemotherapy for psoriasis: a national survey.
Topics: Adult; Azauridine; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Utiliz | 1976 |