Page last updated: 2024-11-07

azauridine and Neoplasms

azauridine has been researched along with Neoplasms in 15 studies

Azauridine: A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"These results also reveal that anticancer drugs other than amino acid analogs and amino acid-depleting enzymes may cause significant changes in amino acid metabolism."1.26Changes in amino acid metabolism caused by 6-azauridine triacetate: relevance to cancer treatment. ( Slavik, M, 1979)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199014 (93.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Cha, YE1
Park, R1
Jang, M1
Park, YI1
Yamamoto, A1
Oh, WK1
Lee, EJ1
Park, J1
KAFKA, V2
MUSIL, J1
PADOVEC, J1
SORM, F5
BRUEMMER, NC1
HOLLAND, JF1
SHEEHE, PR1
KARA, J2
WINKLER, A4
DRAHOVSKY, D2
GREGUSOVA, V3
THURZO, V1
SKODA, J3
HUPKA, S2
KRATOCHVIL, M1
CREASEY, WA1
FINK, ME1
HANDSCHUMACHER, RE2
CALABRESI, P2
PRUSOFF, WH1
SKUPENOVA, A1
MUSIL, I1
GAEK, A1
NOVOTNY, A1
PADOVETS, I1
PAVLOEVKA, I1
PASTERNAK, CA1
Slavik, M1
Bergstresser, PR1
Schreiber, SH1
Weinstein, GD1
Bergevin, PR1
Tormey, DC1
Blom, J1

Reviews

3 reviews available for azauridine and Neoplasms

ArticleYear
A REVIEW OF SOME ASPECTS OF 5-IODODEOXYURIDINE AND AZAURIDINE.
    Cancer research, 1963, Volume: 23

    Topics: Azauridine; Idoxuridine; Metabolism; Neoplasms; Nucleosides; Pharmacology

1963
CURRENT STATUS OF CLINICAL INVESTIGATIONS WITH 6-AZAURIDINE, 5-IODO-2'-DEOXYURIDINE, AND RELATED DERIVATIVES.
    Cancer research, 1963, Volume: 23

    Topics: Antineoplastic Agents; Azauridine; Humans; Idoxuridine; Neoplasms; Nucleosides

1963
Guide to the use of cancer chemotherapeutic agents.
    Modern treatment, 1972, Volume: 9, Issue:2

    Topics: Alkylating Agents; Allopurinol; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents;

1972

Other Studies

12 other studies available for azauridine and Neoplasms

ArticleYear
6-Azauridine Induces Autophagy-Mediated Cell Death via a p53- and AMPK-Dependent Pathway.
    International journal of molecular sciences, 2021, Mar-14, Volume: 22, Issue:6

    Topics: AMP-Activated Protein Kinase Kinases; Antineoplastic Agents; Apoptosis; Autophagic Cell Death; Autop

2021
[Chemotherapy of malignant tumors in gynecology; a report on therapy with azauridine (6-azauracilriboside)].
    Gynaecologia. International monthly review of obstetrics and gynecology. Revue internationale mensuelle d'obstetrique et de gynecologie. Monatsschrift fur Geburtshilfe und Gynakologie, 1961, Volume: 152

    Topics: Antineoplastic Agents; Azauridine; Gynecology; Neoplasms; Nucleosides; Nucleotides

1961
Drug effects on a target metabolic pathway and on mouse tumor growth: azauridine and decarboxylation of orotic acid-7-C-14.
    Cancer research, 1962, Volume: 22

    Topics: Animals; Azauridine; Decarboxylation; Metabolic Networks and Pathways; Mice; Neoplasms; Neoplasms, E

1962
Determination of uridine kinase activity in some human tumours and normal tissues, using 4,5-14-C-6-azauridine as substrate.
    Neoplasma, 1963, Volume: 10

    Topics: Antineoplastic Agents; Azauridine; Humans; Neoplasms; Nucleosides; Phosphorylation; Phosphotransfera

1963
Determination of uridine kinase activity in some human tumours and in leucaemic cells using 4,5-C-14--azauridine as substrate.
    Neoplasma, 1962, Volume: 9

    Topics: Azauridine; Humans; Leukemia; Neoplasms; Nucleosides; Nucleotides; Phosphotransferases; Uridine Kina

1962
The distribution of 6-azauridine in the organs and tumours in man.
    Acta - Unio Internationalis Contra Cancrum, 1962, Volume: 18

    Topics: Azauridine; Biochemical Phenomena; Neoplasms; Nucleosides; Nucleotides

1962
Clinical and pharmacological studies with 2',3',5'-triacetyl-6-azauridine.
    Cancer research, 1963, Volume: 23

    Topics: Azauridine; Neoplasms; Nucleosides; Research

1963
THE SENSITIVITY OF HUMAN LEUKAEMIAS TO 6-AZAURIDINE AND ITS RELATION TO URIDINE-KINASE ACTIVITY.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Antineoplastic Agents; Azauridine; Carboxy-Lyases; Enzyme Inhibitors; Humans; Leukemia; Leukemia, My

1964
[STUDY OF THE EFFECTIVENESS OF DIFFERENT DOSES OF 6-AZAURIDINE IN MALIGNANT TUMORS OF THE FEMALE GENITALIA].
    Voprosy onkologii, 1964, Volume: 10

    Topics: Antineoplastic Agents; Azauridine; Blood Chemical Analysis; Female; Genital Neoplasms, Female; Genit

1964
The biochemical activity of 6-azauridine: interference with pyrimidine metabolism in transplantable mouse tumors.
    The Journal of biological chemistry, 1959, Volume: 234

    Topics: Animals; Azauridine; Mice; Neoplasm Transplantation; Neoplasms; Nucleosides; Nucleotides; Pyrimidine

1959
Changes in amino acid metabolism caused by 6-azauridine triacetate: relevance to cancer treatment.
    Cancer treatment reports, 1979, Volume: 63, Issue:6

    Topics: Amino Acids; Animals; Azauridine; Humans; Neoplasms; Rabbits; Thromboembolism

1979
Systemic chemotherapy for psoriasis: a national survey.
    Archives of dermatology, 1976, Volume: 112, Issue:7

    Topics: Adult; Azauridine; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Utiliz

1976