azauridine has been researched along with Huntington Disease in 1 studies
Azauridine: A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, N | 1 |
| Wu, YY | 1 |
| Feng, Y | 1 |
| Hsieh, WC | 1 |
| Song, JS | 1 |
| Lin, YS | 1 |
| Tseng, YH | 1 |
| Liao, WJ | 1 |
| Chu, YF | 1 |
| Liu, YC | 1 |
| Chang, EC | 1 |
| Liu, CR | 1 |
| Sheu, SY | 1 |
| Su, MT | 1 |
| Kuo, HC | 1 |
| Cohen, SN | 1 |
| Cheng, TH | 1 |
1 other study available for azauridine and Huntington Disease
| Article | Year |
|---|---|
Chemical interference with DSIF complex formation lowers synthesis of mutant huntingtin gene products and curtails mutant phenotypes.
Topics: Alleles; Animals; Azauridine; Cells, Cultured; Disease Models, Animal; DNA Repeat Expansion; Drosoph | 2022 |