azauridine has been researched along with Cleft Palate in 2 studies
Azauridine: A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
Cleft Palate: Congenital fissure of the soft and/or hard palate, due to faulty fusion.
Excerpt | Relevance | Reference |
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" Considering the sensitivity peaks of the morphogenetic processes which were observed, the dose-response relationships, the transformation of the teratogenic to a lethal effect and critical period extension with increasing doses, it was found that the effects of ia and im administered 6-azauridine did not differ." | 1.26 | Embryotoxicity of transplacentally and intraamniotically administered 6-azauridine in mice. ( Dostál, M; Jelínek, R, 1979) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Dostál, M | 2 |
Jelínek, R | 2 |
2 other studies available for azauridine and Cleft Palate
Article | Year |
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Embryotoxicity of transplacentally and intraamniotically administered 6-azauridine in mice.
Topics: Abnormalities, Drug-Induced; Amnion; Animals; Azauridine; Cleft Lip; Cleft Palate; Embryo, Mammalian | 1979 |
Morphogenesis of cleft palate induced by exogenous factors. VI. The question of delayed palatal-process horizontalization.
Topics: Animals; Azauridine; Cleft Palate; Cortisone; Female; Fetus; Gestational Age; Mice; Morphogenesis; O | 1974 |