azauridine has been researched along with Abnormalities, Drug-Induced in 9 studies
Azauridine: A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The reproductive performance of 36 women who had been successfully treated for gestational trophoblastic tumors with multiple courses of cytotoxic agents including methotrexate, 6-mercaptopurine, actinomycin D, and 6-azauridine, between 1962 and 1972, has been studied in comparison with 36 patients who had spontaneously aborted a hydatidiform mole but received no treatment and a control group consisting of 36 women attending an antenatal clinic." | 3.65 | Reproductive performance of women successfully treated for gestational trophoblastic tumors. ( Bagshawe, KD; Walden, PA, 1976) |
| " Considering the sensitivity peaks of the morphogenetic processes which were observed, the dose-response relationships, the transformation of the teratogenic to a lethal effect and critical period extension with increasing doses, it was found that the effects of ia and im administered 6-azauridine did not differ." | 1.26 | Embryotoxicity of transplacentally and intraamniotically administered 6-azauridine in mice. ( Dostál, M; Jelínek, R, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walden, PA | 1 |
| Bagshawe, KD | 1 |
| Dostál, M | 1 |
| Jelínek, R | 3 |
| Bílá, V | 1 |
| Kren, V | 1 |
| Rychter, Z | 2 |
| Peterka, M | 1 |
| Shepard, TH | 1 |
| Lemez, L | 1 |
| Jedlicka, V | 2 |
| Grafnetterová, J | 2 |
| Povýsilová, V | 1 |
| van Wagenen, G | 1 |
| DeConti, RC | 1 |
| Handschumacher, RE | 1 |
| Wade, ME | 1 |
9 other studies available for azauridine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Reproductive performance of women successfully treated for gestational trophoblastic tumors.
Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Azauridine; Child; Child, Preschool; Dactinomyci | 1976 |
Embryotoxicity of transplacentally and intraamniotically administered 6-azauridine in mice.
Topics: Abnormalities, Drug-Induced; Amnion; Animals; Azauridine; Cleft Lip; Cleft Palate; Embryo, Mammalian | 1979 |
Mutant gene--teratogen interaction studied on different genetic backgrounds.
Topics: Abnormalities, Drug-Induced; Alleles; Animals; Azauridine; Crosses, Genetic; Female; Genotype; Heter | 1978 |
[Early detection of teratogenous effects on chick embryo].
Topics: Abnormalities, Drug-Induced; Animals; Azauridine; Chick Embryo; Dactinomycin; Morphogenesis; Thiazin | 1972 |
Teratogenicity from drugs--an increasing problem.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Aminopterin; Amniocentesis; Animals; Anti-Bact | 1974 |
Incidence and localization of heterotopic thymic tissue in the brachiogenic organs of the one-day-old chick.
Topics: Abnormalities, Drug-Induced; Animals; Azauridine; Branchial Region; Chick Embryo; Thymus Gland | 1973 |
Morphological effects of 6-azauridine on the development of the chick.
Topics: Abnormalities, Drug-Induced; Animals; Azauridine; Chick Embryo | 1973 |
Abortifacient and teratogenic effects of triacetyl-6-azauridine in the monkey.
Topics: Abnormalities, Drug-Induced; Abortifacient Agents; Animals; Antimetabolites; Azauridine; Contracepti | 1970 |
[Method for evaluation of the effect of teratogenic agents (6-azauridine) on late development stages].
Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Azauridine; Chick Embryo; Embryonic and Fetal | 1971 |