Page last updated: 2024-10-23

azathioprine and Vitiligo

azathioprine has been researched along with Vitiligo in 8 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Vitiligo: A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached.

Research Excerpts

ExcerptRelevanceReference
"To compare the efficacy of combined low-dose azathioprine and oral PUVA therapy versus oral PUVA therapy alone for the treatment of vitiligo."9.12The efficacy of combined PUVA and low-dose azathioprine for early and enhanced repigmentation in vitiligo patients. ( Radmanesh, M; Saedi, K, 2006)
" We report a case of a 67-year-old man with multiple comorbidities including vitiligo, and a recent diagnosis of inflammatory bowel disease, who developed millimeter-size, circular, brown macules in photoexposed areas both affected and not affected by vitiligo while was taken azathioprine, which disappeared after drug withdrawal."7.83"Eruptive Lentiginosis" in a Patient With Vitiligo and Inflammatory Bowel Disease Treated With Azathioprine. ( Mendoza-Chaparro, C; Murillo-Lázaro, C; Ramos-Rodríguez, C, 2016)
" We report a case of a 67-year-old man with multiple comorbidities including vitiligo, and a recent diagnosis of inflammatory bowel disease, who developed millimeter-size, circular, brown macules in photoexposed areas both affected and not affected by vitiligo while was taken azathioprine, which disappeared after drug withdrawal."3.83"Eruptive Lentiginosis" in a Patient With Vitiligo and Inflammatory Bowel Disease Treated With Azathioprine. ( Mendoza-Chaparro, C; Murillo-Lázaro, C; Ramos-Rodríguez, C, 2016)
"A 52-year-old man presented with high-grade fever, headache and painful vesicular skin rash involving the upper trunk and upper extremities, 8 days after initiation of chemotherapy with azathioprine (50 mg/day), which had been prescribed for acral vitiligo."3.83Azathioprine-induced bullous Sweet's syndrome: a rare association. ( Bar, C; Biswas, SN; Chakraborty, PP; Gantait, K, 2016)
"An association of pemphigus vulgaris with vitiligo or Hashimoto's thyroiditis has not been reported before."1.33Development of pemphigus vulgaris in a patient with vitiligo and Hashimoto's thyroiditis. ( Alli, N; Oztas, P; Tamer, E; Toy, GG; Yalçin, B, 2005)
"Bullous pemphigoid is the most frequent autoimmune blistering skin disease."1.31[Bullous pemphigoid, primary biliary cirrhosis and vitiligo: a multiple autoimmune syndrome?]. ( Géniaux, M; Marcet, B; Sibaud, V; Taieb, A, 2002)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's3 (37.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Patra, S1
Khaitan, BK1
Sharma, VK1
Khanna, N1
Ramos-Rodríguez, C1
Murillo-Lázaro, C1
Mendoza-Chaparro, C1
Biswas, SN1
Chakraborty, PP1
Gantait, K1
Bar, C1
Keskin, M1
Savaş-Erdeve, Ş1
Özbay-Hoşnut, F1
Kurnaz, E1
Çetinkaya, S1
Aycan, Z1
Marcet, B1
Sibaud, V1
Géniaux, M1
Taieb, A1
Yalçin, B1
Tamer, E1
Toy, GG1
Oztas, P1
Alli, N1
Radmanesh, M1
Saedi, K1
Frank, PJ1

Trials

2 trials available for azathioprine and Vitiligo

ArticleYear
A randomized comparative study of the effect of betamethasone oral mini-pulse therapy versus oral azathioprine in progressive nonsegmental vitiligo.
    Journal of the American Academy of Dermatology, 2021, Volume: 85, Issue:3

    Topics: Administration, Oral; Azathioprine; Betamethasone; Combined Modality Therapy; Humans; Vitiligo

2021
The efficacy of combined PUVA and low-dose azathioprine for early and enhanced repigmentation in vitiligo patients.
    The Journal of dermatological treatment, 2006, Volume: 17, Issue:3

    Topics: Administration, Oral; Azathioprine; Humans; Immunosuppressive Agents; PUVA Therapy; Severity of Illn

2006

Other Studies

6 other studies available for azathioprine and Vitiligo

ArticleYear
"Eruptive Lentiginosis" in a Patient With Vitiligo and Inflammatory Bowel Disease Treated With Azathioprine.
    The American Journal of dermatopathology, 2016, Volume: 38, Issue:2

    Topics: Aged; Anti-Inflammatory Agents; Apoptosis; Azathioprine; Biopsy; Drug Eruptions; Gastrointestinal Ag

2016
Azathioprine-induced bullous Sweet's syndrome: a rare association.
    BMJ case reports, 2016, Apr-18, Volume: 2016

    Topics: Azathioprine; Blister; Exanthema; Fever; Headache; Humans; Immunosuppressive Agents; Male; Middle Ag

2016
The first childhood case with coexisting Hashimoto thyroiditis, vitiligo and autoimmune hepatitis.
    The Turkish journal of pediatrics, 2016, Volume: 58, Issue:4

    Topics: Adolescent; Azathioprine; Glucocorticoids; Hashimoto Disease; Hepatitis, Autoimmune; Humans; Male; P

2016
[Bullous pemphigoid, primary biliary cirrhosis and vitiligo: a multiple autoimmune syndrome?].
    Annales de medecine interne, 2002, Volume: 153, Issue:5

    Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Autoimmune Diseases; Azathioprine; Dermatologic Ag

2002
Development of pemphigus vulgaris in a patient with vitiligo and Hashimoto's thyroiditis.
    Journal of endocrinological investigation, 2005, Volume: 28, Issue:6

    Topics: Adult; Autoantibodies; Azathioprine; Female; Humans; Iodide Peroxidase; Pemphigus; Polyendocrinopath

2005
Scleroderma.
    Dermatology online journal, 2001, Volume: 7, Issue:1

    Topics: Alopecia Areata; Azathioprine; Biopsy; Bursitis; Colchicine; Diagnosis, Differential; Drug Therapy,

2001