azathioprine has been researched along with Ventricular Dysfunction, Left in 4 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An unusual case of giant cell myocarditis presenting with cardiogenic shock that dramatically responded to conventional dose of steroids and azathioprine is reported." | 3.70 | Giant cell myocarditis responding to immunosuppressive therapy. ( Chimenti, C; Frustaci, A; Gentiloni, N; Pieroni, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frustaci, A | 2 |
| Russo, MA | 1 |
| Chimenti, C | 2 |
| Tarner, IH | 1 |
| Lange, U | 1 |
| Madlener, K | 1 |
| Classen, K | 1 |
| Kandolf, R | 2 |
| Sperzel, J | 1 |
| Müller-Ladner, U | 1 |
| Möller, K | 1 |
| Klingel, K | 1 |
| Kaiser, U | 1 |
| Thum, M | 1 |
| Bönig, A | 1 |
| Hasenfuss, G | 1 |
| Scholz, KH | 1 |
| Pieroni, M | 1 |
| Gentiloni, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| RANDOMIZED, MULTICENTRIC STUDY COMPARING THE EFFECT OF TWO REGIMENS OF COMBINED IMMUNOSUPPRESSIVE THERAPY IN THE TREATMENT OF INFLAMMATORY CARDIOMYOPATHY CZECH-ICIT (CZECH INFLAMMATORY CARDIOMYOPATHY IMMUNOSUPPRESSION TRIAL)[NCT01877746] | Phase 3 | 234 participants (Anticipated) | Interventional | 2013-01-31 | Recruiting | ||
| Cardiac Magnetic Resonance Evaluation of Myocardial Inflammation Persistence After Acute Myocarditis: Prognostic Relevance[NCT03525639] | 80 participants (Anticipated) | Interventional | 2016-12-06 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for azathioprine and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Randomized study on the efficacy of immunosuppressive therapy in patients with virus-negative inflammatory cardiomyopathy: the TIMIC study.
Topics: Adolescent; Adult; Aged; Azathioprine; Chronic Disease; Double-Blind Method; Heart Failure; Humans; | 2009 |
Randomized study on the efficacy of immunosuppressive therapy in patients with virus-negative inflammatory cardiomyopathy: the TIMIC study.
Topics: Adolescent; Adult; Aged; Azathioprine; Chronic Disease; Double-Blind Method; Heart Failure; Humans; | 2009 |
Randomized study on the efficacy of immunosuppressive therapy in patients with virus-negative inflammatory cardiomyopathy: the TIMIC study.
Topics: Adolescent; Adult; Aged; Azathioprine; Chronic Disease; Double-Blind Method; Heart Failure; Humans; | 2009 |
Randomized study on the efficacy of immunosuppressive therapy in patients with virus-negative inflammatory cardiomyopathy: the TIMIC study.
Topics: Adolescent; Adult; Aged; Azathioprine; Chronic Disease; Double-Blind Method; Heart Failure; Humans; | 2009 |
3 other studies available for azathioprine and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
[A wolf in sheep's clothing: atypical systemic lupus erythematosus (SLE) presenting as cardiovascular disease].
Topics: Antiphospholipid Syndrome; Azathioprine; Biopsy; Diagnosis, Differential; Female; Heart Failure; Hea | 2010 |
[Immunsuppressive therapy in virus-negative eosinophilic inflammatory cardiomyopathy].
Topics: Azathioprine; Biopsy; Cardiac Output, Low; Defibrillators, Implantable; Electrocardiography; Eosinop | 2011 |
Giant cell myocarditis responding to immunosuppressive therapy.
Topics: Adult; Azathioprine; Biopsy; Drug Administration Schedule; Drug Therapy, Combination; Endocardium; F | 2000 |