Page last updated: 2024-10-23

azathioprine and Venous Thrombosis

azathioprine has been researched along with Venous Thrombosis in 21 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Venous Thrombosis: The formation or presence of a blood clot (THROMBUS) within a vein.

Research Excerpts

ExcerptRelevanceReference
"A 39-year-old Afro-Caribbean man with Crohn disease with recurrent deep vein thromboses and pulmonary emboli was commenced on lifelong warfarin treatment."3.77Exacerbation of hereditary warfarin resistance by azathioprine. ( Campbell, S; Gambhir, N; Hadfield, KD; Latif, A; Newman, WG; Pushpakom, SP, 2011)
"A 32-year-old woman with a history of deep vein thrombosis (DVT), steroid-dependent ulcerative colitis, and osteoporosis was prescribed azathioprine for a steroid-sparing effect."3.71A case report of warfarin resistance due to azathioprine and review of the literature. ( Havrda, DE; Rathbun, S; Scheid, D, 2001)
" Hughes-Stovin syndrome was diagnosed and treatment was started with prednisolone and azathioprine."3.71[Giant aneurysms of the pulmonary artery and peripheral venous thrombosis (Hughes-Stovin syndrome): regression with immunosuppressant therapy]. ( Alí-Munive, A; Maldonado, D; Torres-Duque, C; Varón, H, 2001)
"Superficial venous thrombosis (SVT) and deep vein thrombosis (DVT) are the most frequent vascular involvements, affecting altogether 15-40% of BS patients."2.61Vascular Behçet's syndrome: an update. ( Becatti, M; Bettiol, A; Di Scala, G; Emmi, G; Fiorillo, C; Prisco, D; Silvestri, E, 2019)
"Relapse was defined as requiring another antirheumatic/immunosuppressive drug or more than dose of 10 mg/d of prednisolone."1.62Comparison of relapse rates in Behçet's disease with venous involvement on different doses of azathioprine therapy, a retrospective observational study. ( Alpay-Kanitez, N; Bes, C; Celik, S; Cemal Icacan, O; Girgin, S; Omma, A; Yurumez, S, 2021)
"Lower extremity deep vein thrombosis (LEDVT) is a serious complication of Behçet's syndrome."1.56Clinical course of acute deep vein thrombosis of the legs in Behçet's syndrome. ( Cetinkaya, F; Hamuryudan, V; Hatemi, G; Melikoglu, M; Ozguler, Y; Seyahi, E; Tascilar, K; Ugurlu, S; Yazici, H, 2020)
"She was diagnosed with Crohn's disease and right internal iliac vein thrombosis."1.37Internal iliac vein thrombosis in pediatric Crohn's disease. ( Baysoy, G; Besbas, N; Daar, G; Demir, H; Elmas, SA; Haliloğlu, M, 2011)
"Treatment with prednisolone and azathioprine was initiated."1.30[Pyoderma gangrenosum and portal vein thrombosis in a 33-year-old female patient]. ( Berr, F; Halm, U; Mössner, J; Paasch, U; Pönisch, W; Schiefke, I, 1999)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.76)18.2507
2000's8 (38.10)29.6817
2010's10 (47.62)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Ozguler, Y1
Hatemi, G1
Cetinkaya, F1
Tascilar, K1
Hamuryudan, V1
Ugurlu, S1
Seyahi, E1
Yazici, H1
Melikoglu, M1
Girgin, S1
Yurumez, S1
Omma, A1
Celik, S1
Cemal Icacan, O1
Bes, C1
Alpay-Kanitez, N1
Emmi, G1
Bettiol, A1
Silvestri, E1
Di Scala, G1
Becatti, M1
Fiorillo, C1
Prisco, D1
Miller, CP1
Stedman, J1
Nagaratnam, K1
Gray, R1
Bollen, L2
Wuyts, J1
Vermeire, S2
Gils, A2
Vande Casteele, N1
Ballet, V1
van Assche, G1
Ferrante, M1
Hsu, WY1
Chiou, SS1
Liao, YM1
Shu, HL1
Zeng, YS1
Wong, CC1
Lin, PC1
Calderón, FM1
Valladares, VG1
Ballesteros, AM1
de la Merced Ayala, MC1
Pushpakom, SP1
Gambhir, N1
Latif, A1
Hadfield, KD1
Campbell, S1
Newman, WG1
McKiernan, PJ1
Baysoy, G1
Daar, G1
Demir, H1
Elmas, SA1
Haliloğlu, M1
Besbas, N1
Richmond, BW1
Cole, MB1
Dash, A1
Eyler, A1
Boomershine, CS1
Yoshida, S1
Takeuchi, T1
Yoshikawa, A1
Ozaki, T1
Fujiki, Y1
Hata, K1
Makino, S1
Hanafusa, T1
Thomas, RV1
Bessos, H1
Turner, ML1
Horn, EH1
Ludlam, CA1
Chen, HC1
Lai, JH1
Huang, GS1
Gao, HW1
Chen, CH1
Kuo, SY1
Chang, DM1
Brueck, M1
Runde, T1
Rauber, K1
Kramer, W1
Ng, HJ1
Crowther, MA1
Mannari, D1
Liu, C1
Hughes, D1
Mehta, A1
Schiefke, I1
Halm, U1
Paasch, U1
Pönisch, W1
Berr, F1
Mössner, J1
Havrda, DE1
Rathbun, S1
Scheid, D1
Alí-Munive, A1
Varón, H1
Maldonado, D1
Torres-Duque, C1

Reviews

3 reviews available for azathioprine and Venous Thrombosis

ArticleYear
Vascular Behçet's syndrome: an update.
    Internal and emergency medicine, 2019, Volume: 14, Issue:5

    Topics: Azathioprine; Behcet Syndrome; Cyclophosphamide; Cyclosporins; Humans; Immunosuppressive Agents; Tum

2019
Systemic lupus erythematosus with simultaneous onset of Kikuchi-Fujimoto's disease complicated with antiphospholipid antibody syndrome: a case report and review of the literature.
    Rheumatology international, 2005, Volume: 25, Issue:4

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents; Anticoagulants; Antiphospholipid Syndrome; An

2005
Azathioprine and inhibition of the anticoagulant effect of warfarin: evidence from a case report and a literature review.
    The American journal of geriatric pharmacotherapy, 2006, Volume: 4, Issue:1

    Topics: Aged; Anticoagulants; Azathioprine; Drug Antagonism; Female; Humans; Immunosuppressive Agents; Inter

2006

Other Studies

18 other studies available for azathioprine and Venous Thrombosis

ArticleYear
Clinical course of acute deep vein thrombosis of the legs in Behçet's syndrome.
    Rheumatology (Oxford, England), 2020, 04-01, Volume: 59, Issue:4

    Topics: Adult; Azathioprine; Behcet Syndrome; Cyclophosphamide; Cyclosporine; Disease Progression; Female; F

2020
Comparison of relapse rates in Behçet's disease with venous involvement on different doses of azathioprine therapy, a retrospective observational study.
    International journal of rheumatic diseases, 2021, Volume: 24, Issue:4

    Topics: Adult; Azathioprine; Behcet Syndrome; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; P

2021
Headache in a young male: the clot thickens.
    BMJ case reports, 2013, May-22, Volume: 2013

    Topics: Adult; Anticoagulants; Azathioprine; Brain Infarction; Cranial Sinuses; Crohn Disease; Headache; Hep

2013
Identification of an inflammatory bowel disease patient with a deep vein thrombosis and an altered clot lysis profile.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2016, Volume: 27, Issue:2

    Topics: Adult; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Azathioprine; Female; Fibrin Clot Ly

2016
Thromboembolism as an important complication of inflammatory bowel disease.
    European journal of gastroenterology & hepatology, 2016, Volume: 28, Issue:1

    Topics: Adalimumab; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; C

2016
Successful management of multilineage autoimmune cytopenia complicated with severe infection and deep vein thrombosis in a patient with Hodgkin lymphoma post-autologous hematopoietic stem cell transplantation.
    Pediatric transplantation, 2016, Volume: 20, Issue:1

    Topics: Adolescent; Autoimmune Diseases; Azathioprine; Bone Marrow Transplantation; Cell Lineage; Cyclophosp

2016
[Vaginal ulcers in Behçet disease].
    Ginecologia y obstetricia de Mexico, 2008, Volume: 76, Issue:3

    Topics: Adult; Anticoagulants; Azathioprine; Behcet Syndrome; Female; Humans; Immunosuppressive Agents; Oral

2008
Exacerbation of hereditary warfarin resistance by azathioprine.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2011, Volume: 17, Issue:3

    Topics: Adult; Amino Acid Substitution; Anticoagulants; Antimetabolites; Azathioprine; Crohn Disease; Drug R

2011
Long-term care following paediatric liver transplantation.
    Archives of disease in childhood. Education and practice edition, 2011, Volume: 96, Issue:3

    Topics: Azathioprine; Calcineurin Inhibitors; Child; Continuity of Patient Care; Glucocorticoids; Graft Reje

2011
Internal iliac vein thrombosis in pediatric Crohn's disease.
    Journal of Crohn's & colitis, 2011, Volume: 5, Issue:1

    Topics: Anticoagulants; Azathioprine; Child; Crohn Disease; Early Diagnosis; Female; Heparin; Humans; Iliac

2011
A tale of two rashes.
    The American journal of medicine, 2011, Volume: 124, Issue:5

    Topics: Aged; Antihypertensive Agents; Azathioprine; Complement C4; Cryoglobulinemia; Diagnosis, Differentia

2011
Good response to infliximab in a patient with deep vein thrombosis associated with Behçet disease.
    Modern rheumatology, 2012, Volume: 22, Issue:5

    Topics: Antibodies, Monoclonal; Antirheumatic Agents; Azathioprine; Behcet Syndrome; Cyclosporine; Drug Resi

2012
The successful use of plasma exchange and immunosuppression in the management of acquired Glanzmann's thrombasthenia.
    British journal of haematology, 2002, Volume: 119, Issue:3

    Topics: Anticoagulants; Azathioprine; Combined Modality Therapy; Female; Gastrointestinal Hemorrhage; Hepari

2002
[Fibrinogen-guided thrombolysis with urokinase of a portal and mesenterial venous thrombosis during an acute episode of ulcerative colitis].
    Deutsche medizinische Wochenschrift (1946), 2006, Jan-20, Volume: 131, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Colitis, Ulcerative; Diarrhea; Drug Therapy, Combinat

2006
The role of heparin in alleviating complement-mediated acute intravascular haemolysis.
    Acta haematologica, 2008, Volume: 119, Issue:3

    Topics: 3' Untranslated Regions; Acute Disease; Adult; Anemia, Hemolytic, Autoimmune; Azathioprine; Combined

2008
[Pyoderma gangrenosum and portal vein thrombosis in a 33-year-old female patient].
    Deutsche medizinische Wochenschrift (1946), 1999, Feb-12, Volume: 124, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Anticoagulants; Antineoplastic Agents; Ascites; Azathioprine; Bone

1999
A case report of warfarin resistance due to azathioprine and review of the literature.
    Pharmacotherapy, 2001, Volume: 21, Issue:3

    Topics: Adult; Anticoagulants; Azathioprine; Drug Resistance; Female; Humans; Immunosuppressive Agents; Inte

2001
[Giant aneurysms of the pulmonary artery and peripheral venous thrombosis (Hughes-Stovin syndrome): regression with immunosuppressant therapy].
    Archivos de bronconeumologia, 2001, Volume: 37, Issue:11

    Topics: Adult; Aneurysm; Anti-Inflammatory Agents; Azathioprine; Humans; Immunosuppressive Agents; Male; Per

2001