azathioprine has been researched along with Vascular Diseases in 27 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Vascular Diseases: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Chlorambucil may hold advantages over the immunosuppressive drugs normally recommended in this condition, azathioprine and cyclophosphamide, as it appears less liable to cause important marrow suppression and, unlike cyclophosphamide is not associated with alopecia and haemorrhagic cystitis." | 7.65 | Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil. ( Dunnill, MS; Halley, W; Holt, JM; Oliver, DO; Snaith, ML; Stephenson, AC, 1973) |
| " Chlorambucil may hold advantages over the immunosuppressive drugs normally recommended in this condition, azathioprine and cyclophosphamide, as it appears less liable to cause important marrow suppression and, unlike cyclophosphamide is not associated with alopecia and haemorrhagic cystitis." | 3.65 | Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil. ( Dunnill, MS; Halley, W; Holt, JM; Oliver, DO; Snaith, ML; Stephenson, AC, 1973) |
| "Atypical Cogan's syndrome is more commonly associated with systemic manifestations than typical disease, and may be refractory to immunosuppressive treatment." | 2.45 | Cogan's syndrome: present and future directions. ( Harney, S; Molloy, M; Murphy, G; Shanahan, F; Sullivan, MO, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (74.07) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 3 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murphy, G | 1 |
| Sullivan, MO | 1 |
| Shanahan, F | 1 |
| Harney, S | 1 |
| Molloy, M | 1 |
| van Winden, M | 1 |
| Salu, P | 1 |
| Patel, JK | 1 |
| Kobashigawa, JA | 1 |
| Arora, S | 1 |
| Ueland, T | 1 |
| Wennerblom, B | 1 |
| Sigurdadottir, V | 1 |
| Eiskjær, H | 1 |
| Bøtker, HE | 1 |
| Ekmehag, B | 1 |
| Jansson, K | 1 |
| Mortensen, SA | 1 |
| Saunamaki, K | 1 |
| Simonsen, S | 1 |
| Gude, E | 1 |
| Bendz, B | 1 |
| Solbu, D | 1 |
| Aukrust, P | 1 |
| Gullestad, L | 1 |
| Allison, AC | 1 |
| Weitz, H | 1 |
| Gokel, JM | 1 |
| Loeschke, K | 1 |
| Possinger, K | 1 |
| Eder, M | 1 |
| Choy, BY | 1 |
| Walker, RG | 1 |
| Becker, GJ | 1 |
| Nelius, D | 1 |
| Faust, G | 1 |
| Zöller, B | 1 |
| Brinkrolf, H | 1 |
| Nicolle, MW | 1 |
| McLachlan, RS | 1 |
| Rautenberg, W | 1 |
| Hennerici, M | 1 |
| Aulich, A | 1 |
| Hölzle, E | 1 |
| Lakomek, HJ | 1 |
| Read, AE | 1 |
| Wiesner, RH | 1 |
| LaBrecque, DR | 1 |
| Tifft, JG | 1 |
| Mullen, KD | 1 |
| Sheer, RL | 1 |
| Petrelli, M | 1 |
| Ricanati, ES | 1 |
| McCullough, AJ | 1 |
| Sommer, BG | 1 |
| Henry, ML | 1 |
| Ferguson, RM | 1 |
| Liaño, F | 1 |
| Moreno, A | 1 |
| Teruel, JL | 1 |
| Lamas, S | 1 |
| Matesanz, R | 1 |
| Ortuño, J | 1 |
| Deicher, H | 1 |
| Gerebtzoff, A | 1 |
| Sraer, JD | 1 |
| Beaufils, P | 1 |
| Morel-Maroger, L | 1 |
| Richet, G | 1 |
| Claman, HN | 1 |
| Karr, RM | 1 |
| Kohler, PF | 1 |
| Mass, MF | 1 |
| McIntosh, RM | 1 |
| Sams, WM | 1 |
| Small, P | 1 |
| Stanford, RE | 1 |
| Thorne, EG | 1 |
| Cobau, CD | 1 |
| Sheon, RP | 1 |
| Kirsner, AB | 1 |
| Conn, J | 1 |
| Krumlovsky, FA | 1 |
| Del Greco, F | 1 |
| Simon, NM | 1 |
| Nicholls, A | 1 |
| Snaith, ML | 2 |
| Maini, RN | 1 |
| Scott, JT | 1 |
| Varkarakis, MJ | 1 |
| Bhanalaph, T | 1 |
| Murphy, GP | 1 |
| Kahn, DR | 1 |
| Dufek, JH | 1 |
| Oberman, HA | 1 |
| Beck, ML | 1 |
| Bree, M | 1 |
| Kirsh, MM | 1 |
| Moores, WY | 1 |
| Prior, M | 1 |
| Holt, JM | 1 |
| Oliver, DO | 1 |
| Dunnill, MS | 1 |
| Halley, W | 1 |
| Stephenson, AC | 1 |
| Fauci, AS | 1 |
| Wolff, SM | 1 |
| Schulz, HJ | 1 |
| Reitzig, P | 1 |
| Lisewski, G | 1 |
| Dietze, F | 1 |
| Lichtman, MA | 1 |
| Hoyer, LW | 1 |
| Sears, DA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I/II Trial of TNFR:Fc (Etanercept) in Patients With Wegener's Granulomatosis[NCT00001901] | Phase 2 | 60 participants | Interventional | 1999-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for azathioprine and Vascular Diseases
| Article | Year |
|---|---|
Cogan's syndrome: present and future directions.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Dose-Response Relationship, Drug; Fatal Outcome; Femal | 2009 |
Mechanisms of action of mycophenolate mofetil.
Topics: Azathioprine; B-Lymphocytes; Cytokines; Humans; Immunosuppressive Agents; Mycophenolic Acid; Nitric | 2005 |
[Immunovasculitis-- differential diagnosis and therapy of inflammatory systemic diseases].
Topics: Adult; Angiography; Arthritis, Rheumatoid; Autoimmune Diseases; Azathioprine; Diagnosis, Differentia | 1976 |
2 trials available for azathioprine and Vascular Diseases
| Article | Year |
|---|---|
Effect of everolimus introduction on cardiac allograft vasculopathy--results of a randomized, multicenter trial.
Topics: Aged; Azathioprine; C-Reactive Protein; Calcineurin Inhibitors; Disease Progression; Dose-Response R | 2011 |
Proceedings: Controlled trial of azathioprine in rheumatoid vasculitis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Humans; Imm | 1973 |
22 other studies available for azathioprine and Vascular Diseases
| Article | Year |
|---|---|
Branch retinal artery occlusion with visual field and multifocal erg in Susac syndrome: a case report.
Topics: Arteries; Azathioprine; Brain; Cochlea; Cyclophosphamide; Drug Administration Schedule; Drug Therapy | 2010 |
Everolimus for cardiac allograft vasculopathy--every patient, at any time?
Topics: Azathioprine; Calcineurin Inhibitors; Cell Proliferation; Disease Progression; Drug Therapy, Combina | 2011 |
Veno-occlusive disease of the liver in patients receiving immunosuppressive therapy.
Topics: Adult; Azathioprine; Humans; Kidney Transplantation; Liver; Male; Prednisolone; Vascular Diseases; V | 1982 |
Vasculopathy in cyclosporine-treated renal allografts: possible protection by diltiazem.
Topics: Adult; Arterioles; Azathioprine; Cyclosporine; Diltiazem; Female; Humans; Image Processing, Computer | 1994 |
[Immunosuppressive treatment in autoimmune vasculities].
Topics: Adult; Aged; Arteritis; Azathioprine; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Middle | 1975 |
Microangiopathy with retinopathy, encephalopathy, and deafness (RED-M) and systemic features.
Topics: Adult; Antibodies; Azathioprine; Brain Diseases; Cardiolipins; Cyclophosphamide; Female; Humans; Imm | 1991 |
Immunosuppressive therapy and Sneddon's syndrome.
Topics: Adult; Azathioprine; Cerebrovascular Disorders; Female; Humans; Male; Middle Aged; Skin Diseases; Sy | 1988 |
Hepatic veno-occlusive disease associated with renal transplantation and azathioprine therapy.
Topics: Adult; Azathioprine; Cyclophosphamide; Cytomegalovirus Infections; Esophageal and Gastric Varices; F | 1986 |
Cyclosporine-associated renal arteriopathy.
Topics: Antilymphocyte Serum; Azathioprine; Biopsy; Cyclosporins; Epoprostenol; Graft Rejection; Humans; Kid | 1986 |
Hepatic veno-occlusive disease and renal transplantation.
Topics: Azathioprine; Humans; Kidney Transplantation; Liver; Postoperative Complications; Vascular Diseases | 1986 |
[Recommendations for immunosuppressive therapy in systemic lupus erythematosus].
Topics: Adrenocorticotropic Hormone; Antibodies, Antinuclear; Arthritis, Juvenile; Azathioprine; Bone Marrow | 1972 |
[Immunosuppressive agents].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Anemia, Hemolytic, Autoimmune; Antibodies; Azathioprine; | 1974 |
Vascular nephropathies with acute renal failure.
Topics: Acute Kidney Injury; Antihypertensive Agents; Azathioprine; Biopsy; Capillaries; Heparin; Humans; Hy | 1973 |
Systemic (allergic?) vasculitis.
Topics: Antigen-Antibody Complex; Azathioprine; Complement System Proteins; Creatinine; Diphenhydramine; Ery | 1974 |
Immunosuppressive drugs and acute leukemia.
Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Cyclophosphamide; Dose-Response Relationship, Drug; Human | 1973 |
Calciphylaxis: etiology of progressive vascular calcification and gangrene?
Topics: Adult; Autopsy; Azathioprine; Calcinosis; Calciphylaxis; Female; Gangrene; Graft Rejection; Hand; Hu | 1973 |
Effect of estrogens on canine renal allografts.
Topics: Animals; Azathioprine; Blood Urea Nitrogen; Capillary Permeability; Dogs; Drug Synergism; Edema; Est | 1974 |
The effect of heparin and dipyridamole on chronic vascular lesions in monkey cardiac allografts.
Topics: Animals; Azathioprine; Dipyridamole; Female; Haplorhini; Heart Transplantation; Heparin; Macaca; Mal | 1972 |
Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil.
Topics: Adult; Alopecia; Amenorrhea; Azathioprine; Biopsy; Bone Marrow; Chlorambucil; Cyclophosphamide; Cyst | 1973 |
Wegener's granulomatosis: studies in eighteen patients and a review of the literature.
Topics: Adult; Aged; Azathioprine; Biopsy; Corneal Ulcer; Cyclophosphamide; Diagnosis, Differential; Ear Dis | 1973 |
[Malabsorption syndrome and intestinal pseudoobstruction in primary vascular and heart amyloidosis].
Topics: Adult; Amyloidosis; Antibody Formation; Antigen-Antibody Complex; Azathioprine; Chloramphenicol; Cys | 1973 |
Erythrocyte deformation and hemolytic anemia coincident with the microvascular disease of rejecting renal homotransplants.
Topics: Adult; Anemia, Hemolytic; Azathioprine; Erythrocytes; Female; Humans; Kidney Transplantation; Male; | 1968 |