azathioprine has been researched along with Uveitis, Anterior in 20 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Uveitis, Anterior: Inflammation of the anterior uvea comprising the iris, angle structures, and the ciliary body. Manifestations of this disorder include ciliary injection, exudation into the anterior chamber, iris changes, and adhesions between the iris and lens (posterior synechiae). Intraocular pressure may be increased or reduced.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nine patients with peripheral chronic cyclitis and cystic edema of the macula were treated with azathioprine and small doses of corticosteroids." | 9.04 | [Treatment with azathioprine of peripheral chronic cyclitis with cystoid edema of the macula (author's transl)]. ( Charamis, I; Skouras, I, 1977) |
| "Nine patients with peripheral chronic cyclitis and cystic edema of the macula were treated with azathioprine and small doses of corticosteroids." | 5.04 | [Treatment with azathioprine of peripheral chronic cyclitis with cystoid edema of the macula (author's transl)]. ( Charamis, I; Skouras, I, 1977) |
| "Ocular lesions, the main morbidity of Behcet's disease (BD), are the most difficult to treat." | 2.75 | Rituximab in intractable ocular lesions of Behcet's disease; randomized single-blind control study (pilot study). ( Akhlaghi, M; Chams-Davatchi, C; Davatchi, F; Faezi, T; Naderi, N; Nadji, A; Rezaipoor, M; Sadeghi-Abdollahi, B; Shahram, F; Shams, H, 2010) |
| " The selection criteria were as follows: (population) noninfectious AU patients, adults; (intervention) immunomodulatory drugs (any dose, regimen, route of administration, duration of treatment); (outcome) control of inflammation, steroid-sparing effect, AU flares, adverse events, and so on; (study design) systematic literature reviews, randomized controlled trials, and observational studies." | 2.55 | Efficacy and safety of immunomodulatory drugs in patients with anterior uveitis: A systematic literature review. ( Cordero-Coma, M; Espinosa, G; Gómez-Gómez, A; Herreras, JM; Loza, E; Morales, JMGR; Muñoz-Fernández, S; Rosario, MP, 2017) |
| "Azathioprine was used at 2-3 mg/kg daily." | 1.40 | Combination of pulse cyclophosphamide and azathioprine in ocular manifestations of Behcet's disease: longitudinal study of up to 10 years. ( Akhlaghi, M; Ashofteh, F; Chams-Davatchi, C; Davatchi, F; Faezi, T; Ghodsi, Z; Mohtasham, N; Nadji, A; Sadeghi Abdollahi, B; Shahram, F; Shams, H, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 6 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mohammadi, M | 1 |
| Shahram, F | 4 |
| Shams, H | 3 |
| Akhlaghi, M | 3 |
| Ashofteh, F | 2 |
| Davatchi, F | 4 |
| Gómez-Gómez, A | 1 |
| Loza, E | 1 |
| Rosario, MP | 1 |
| Espinosa, G | 1 |
| Morales, JMGR | 1 |
| Herreras, JM | 1 |
| Muñoz-Fernández, S | 1 |
| Cordero-Coma, M | 1 |
| Sadeghi Abdollahi, B | 1 |
| Nadji, A | 3 |
| Chams-Davatchi, C | 2 |
| Faezi, T | 2 |
| Ghodsi, Z | 1 |
| Mohtasham, N | 1 |
| Sah, BP | 1 |
| Sharma, B | 1 |
| Iannuzzi, MC | 1 |
| Rezaipoor, M | 1 |
| Sadeghi-Abdollahi, B | 1 |
| Naderi, N | 1 |
| Paroli, MP | 1 |
| Spinucci, G | 1 |
| Bruscolini, A | 1 |
| La Cava, M | 1 |
| Abicca, I | 1 |
| Chams, H | 1 |
| Jamshidi, A | 1 |
| Akbarian, M | 1 |
| Gharibdoost, F | 1 |
| Klaeger, AJ | 1 |
| Tran, VT | 1 |
| Hiroz, CA | 1 |
| Morisod, L | 1 |
| Herbort, CP | 1 |
| Bachta, A | 1 |
| Tłustochowicz, M | 1 |
| Lehmann, H | 1 |
| Struve, C | 1 |
| Giełdanowski, J | 1 |
| Doskocz, W | 1 |
| Gion, N | 1 |
| Stavrou, P | 1 |
| Foster, CS | 1 |
| Wurm, K | 1 |
| Charamis, I | 1 |
| Skouras, I | 1 |
| James, DG | 1 |
| Friedmann, AI | 1 |
| Graham, E | 1 |
| Pietruschka, G | 1 |
| Kölle, G | 2 |
| Stoeber, E | 1 |
| Schöntag, W | 1 |
| Mathews, JD | 1 |
| Crawford, BA | 1 |
| Bignell, JL | 1 |
| Mackay, IR | 1 |
| Cerný, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Low-dose IL-2 Treatment on Behcet's Disease[NCT04065672] | Phase 2 | 15 participants (Anticipated) | Interventional | 2019-11-12 | Recruiting | ||
| A Double Blind Cross Over Clinical Trial to Determine Colchicine Efficacy in Behcet's Disease[NCT00700297] | Phase 2 | 169 participants (Actual) | Interventional | 2002-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for azathioprine and Uveitis, Anterior
| Article | Year |
|---|---|
Efficacy and safety of immunomodulatory drugs in patients with anterior uveitis: A systematic literature review.
Topics: Adalimumab; Adult; Antibodies, Monoclonal; Azathioprine; Cyclosporine; Female; Humans; Immunosuppres | 2017 |
[Systemic management of autoimmune anterior uveitis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Autoimmune Diseases; Azathioprine; | 2005 |
[Sarcoidosis therapy and its problems today].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Anti-Inflammatory Agents; Antineoplasti | 1978 |
5 trials available for azathioprine and Uveitis, Anterior
| Article | Year |
|---|---|
High-dose intravenous steroid pulse therapy in ocular involvement of Behcet's disease: a pilot double-blind controlled study.
Topics: Administration, Intravenous; Adult; Azathioprine; Behcet Syndrome; Cyclophosphamide; Double-Blind Me | 2017 |
Rituximab in intractable ocular lesions of Behcet's disease; randomized single-blind control study (pilot study).
Topics: Adolescent; Adult; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Behcet Syndrome; Cyclophosp | 2010 |
Azathioprine and low dose pulse cyclophosphamide in severe ocular lesions of Behçet's disease. A preliminary report.
Topics: Azathioprine; Behcet Syndrome; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combina | 2003 |
[Treatment with azathioprine of peripheral chronic cyclitis with cystoid edema of the macula (author's transl)].
Topics: Adult; Azathioprine; Clinical Trials as Topic; Cysts; Dexamethasone; Edema; Female; Fluorescein Angi | 1977 |
Azathioprine in active chronic iridocyclitis. A double-blind controlled trial.
Topics: Adult; Aqueous Humor; Azathioprine; Chronic Disease; Clinical Trials as Topic; Humans; Intraocular P | 1969 |
12 other studies available for azathioprine and Uveitis, Anterior
| Article | Year |
|---|---|
Combination of pulse cyclophosphamide and azathioprine in ocular manifestations of Behcet's disease: longitudinal study of up to 10 years.
Topics: Azathioprine; Behcet Syndrome; Cyclophosphamide; Drug Resistance; Drug Therapy, Combination; Humans; | 2014 |
Isolated extraocular orbital mass: a rare presentation of sarcoidosis.
Topics: Aged; Azathioprine; Biopsy; Diplopia; Drug Administration Schedule; Drug Therapy, Combination; Eyeli | 2016 |
Uveitis preceding Crohn's disease by 8 years.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Child; Child, Preschool; Crohn Disease; Drug | 2011 |
Use of ultrasound biomicroscopy, indocyanine green angiography and HLA-B51 testing as adjunct methods in the appraisal of Behçet's uveitis.
Topics: Adolescent; Adult; Azathioprine; Behcet Syndrome; Child; Colchicine; Coloring Agents; Cyclosporine; | 2004 |
[Liver changes in Wegener's granulomatosis (author's transl)].
Topics: Azathioprine; Female; Glucocorticoids; Granulomatosis with Polyangiitis; Humans; Liver; Lung; Middle | 1981 |
Immunosuppressive drugs in the treatment of immunologic iridocyclitis in the rabbit.
Topics: Animals; Aqueous Humor; Azathioprine; Busulfan; Drug Evaluation, Preclinical; Female; Hypersensitivi | 1980 |
Immunomodulatory therapy for chronic tubulointerstitial nephritis-associated uveitis.
Topics: Adolescent; Adult; Azathioprine; Chronic Disease; Cyclosporine; Female; Follow-Up Studies; Humans; I | 2000 |
Uveitis. A series of 368 patients.
Topics: Adolescent; Adult; Aged; Antigen-Antibody Complex; Autoantibodies; Azathioprine; Child; Child, Presc | 1976 |
[Contribution on the clinical problems of idiopathic panuveitis (author's transl)].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Azathioprine; Child; Child, Preschool; Chorioretinit | 1974 |
[Long term therapy of rheumatoid arthritis in children].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis, Juvenile; Azathioprine; Child; Chlo | 1970 |
[Immunosuppressive agents in the basic therapy of visceral forms of rheumatoid arthritis in children].
Topics: Adolescent; Adrenal Cortex Hormones; Amyloidosis; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathi | 1972 |
[Therapy of endogenous intraocular inflammation with azathioprine].
Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Chronic Disease; Drug Synergism; Female; Humans; | 1971 |