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azathioprine and Urinary Bladder Neoplasms

azathioprine has been researched along with Urinary Bladder Neoplasms in 16 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.

Research Excerpts

ExcerptRelevanceReference
"Side effects of long-term use of azathioprine in myasthenia gravis are infrequently reported."7.71Prostatic involvement of a testicular lymphoma in a patient with myasthenia gravis on long-term azathioprine. ( Barthelmes, L; Seale, JR; Thomas, KJ, 2002)
"Surgical trauma and cytomegalovirus infections are discussed as etiologic factors."5.27Nephrogenic adenoma of the bladder after kidney transplantation: spontaneous improvement with azathioprine removal; surgical trauma and cytomegalovirus infection as possible etiologic factors. ( Beaudry, C; Bertrand, PE; Dandavino, R; Houde, M; Lamoureux, C; Laplante, L; Laverdiere, M, 1983)
"Side effects of long-term use of azathioprine in myasthenia gravis are infrequently reported."3.71Prostatic involvement of a testicular lymphoma in a patient with myasthenia gravis on long-term azathioprine. ( Barthelmes, L; Seale, JR; Thomas, KJ, 2002)
"A prospective study in the United Kingdom of 1,634 patients without transplants treated with immunosuppressive drugs (68 percent with azathioprine, 28 percent with cyclophosphamide) found an excess of non-Hodgkin's lymphoma and squamous cell skin cancer, suggesting that the excesses (although larger) of the same malignancies found among transplant recipients are not due solely to the foreign antigens of the graft."3.67Incidence of cancer in rheumatoid arthritis and other disorders after immunosuppressive treatment. ( Kinlen, LJ, 1985)
" The initial loading dosage was 2 mg/d, and the next dosage was 1 mg/d."1.35Rapamycin instead of mycophenolate mofetil or azathioprine in treatment of post-renal transplantation urothelial carcinoma. ( Hu, XP; Ma, LL; Wang, W; Wang, Y; Yang, XY; Yin, H; Zhang, XD, 2009)
"Surgical trauma and cytomegalovirus infections are discussed as etiologic factors."1.27Nephrogenic adenoma of the bladder after kidney transplantation: spontaneous improvement with azathioprine removal; surgical trauma and cytomegalovirus infection as possible etiologic factors. ( Beaudry, C; Bertrand, PE; Dandavino, R; Houde, M; Lamoureux, C; Laplante, L; Laverdiere, M, 1983)
"Data on the possible increased risk of malignancy in rheumatoid arthritis are still being collected, and until further information is available, the use of immunosuppressive drugs, particularly alkylating agents, in the treatment of rheumatoid arthritis should be reserved for patients with severe progressive disease or life-threatening complications."1.27Incidence of neoplasms in patients with rheumatoid arthritis exposed to different treatment regimens. ( Hazleman, B, 1985)
" The correlation between these is poor, in many patients, at the dosage used in man."1.26The comparative incidence of malignant disease in rheumatoid arthritics exposed to different treatment regimens. ( Hazleman, BL, 1982)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199011 (68.75)18.7374
1990's1 (6.25)18.2507
2000's3 (18.75)29.6817
2010's0 (0.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Vuille-Lessard, É1
Montani, M1
Bosch, J1
Semmo, N1
Hu, XP1
Ma, LL1
Wang, Y1
Yin, H1
Wang, W1
Yang, XY1
Zhang, XD1
Wang, HB1
Hsieh, HH1
Chen, YT1
Chiang, CY1
Cheng, YT1
Barthelmes, L1
Thomas, KJ1
Seale, JR1
Beaudry, C1
Bertrand, PE1
Laplante, L1
Houde, M1
Lamoureux, C1
Laverdiere, M1
Dandavino, R1
Or, R1
Kleinman, Y1
Chajek-Shaul, T1
Hazleman, BL1
Scharf, J1
Nahir, M1
Eidelman, S1
Jacobs, R1
Levin, D1
Cohen, SM1
Fukushima, S1
Tsuda, H1
Murasaki, G1
Ito, N1
Gordon, HL1
Kerr, SG1
Campo, MS1
Jarrett, WF1
Barron, R1
O'Neil, BW1
Smith, KT1
Hazleman, B1
Kinlen, LJ1
Birkeland, SA1
Kemp, E1
Biggs, AW1
Siegel, JH1
Janis, R1
Alper, JC1
Schutte, H1
Robbins, L1
Blaufox, MD1

Other Studies

16 other studies available for azathioprine and Urinary Bladder Neoplasms

ArticleYear
Autoimmune hepatitis triggered by SARS-CoV-2 vaccination.
    Journal of autoimmunity, 2021, Volume: 123

    Topics: 2019-nCoV Vaccine mRNA-1273; Aged; Autoantibodies; Azathioprine; Carcinoma, Transitional Cell; Causa

2021
Rapamycin instead of mycophenolate mofetil or azathioprine in treatment of post-renal transplantation urothelial carcinoma.
    Chinese medical journal, 2009, Jan-05, Volume: 122, Issue:1

    Topics: Adult; Azathioprine; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle

2009
The outcome of post-transplant transitional cell carcinoma in 10 renal transplant recipients.
    Clinical transplantation, 2002, Volume: 16, Issue:6

    Topics: Adult; Azathioprine; Carcinoma, Transitional Cell; Cyclosporine; Female; Humans; Immunosuppressive A

2002
Prostatic involvement of a testicular lymphoma in a patient with myasthenia gravis on long-term azathioprine.
    Leukemia & lymphoma, 2002, Volume: 43, Issue:12

    Topics: Azathioprine; Fatal Outcome; Humans; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Male; Middle

2002
Nephrogenic adenoma of the bladder after kidney transplantation: spontaneous improvement with azathioprine removal; surgical trauma and cytomegalovirus infection as possible etiologic factors.
    The Journal of urology, 1983, Volume: 130, Issue:6

    Topics: Adenoma; Adult; Azathioprine; Cytomegalovirus Infections; Female; Humans; Intraoperative Complicatio

1983
Azathioprine and urinary bladder tumor.
    Annals of internal medicine, 1983, Volume: 99, Issue:5

    Topics: Adult; Azathioprine; Carcinoma, Transitional Cell; Humans; Lupus Erythematosus, Systemic; Male; Urin

1983
The comparative incidence of malignant disease in rheumatoid arthritics exposed to different treatment regimens.
    Annals of the rheumatic diseases, 1982, Volume: 41 Suppl 1

    Topics: Adult; Aged; Animals; Arthritis, Rheumatoid; Azathioprine; Carcinoma, Transitional Cell; Chromosome

1982
Carcinoma of the bladder with azathioprine therapy.
    JAMA, 1977, Jan-10, Volume: 237, Issue:2

    Topics: Aged; Azathioprine; Carcinoma, Transitional Cell; Colitis, Ulcerative; Female; Humans; Male; Urinary

1977
Effect of azathiopurine and OK-432 on urinary bladder carcinogenesis in rats.
    Gan, 1978, Volume: 69, Issue:6

    Topics: Animals; Azathioprine; Biological Products; Butylhydroxybutylnitrosamine; Drug Synergism; Immunosupp

1978
Nephrogenic adenoma of bladder in immunosuppressed renal transplantation.
    Urology, 1975, Volume: 5, Issue:2

    Topics: Adenoma; Adult; Azathioprine; Graft Rejection; Humans; Immunosuppression Therapy; Kidney Transplanta

1975
Association of bovine papillomavirus type 2 and bracken fern with bladder cancer in cattle.
    Cancer research, 1992, Dec-15, Volume: 52, Issue:24

    Topics: Animals; Azathioprine; Bovine papillomavirus 1; Cattle; Cattle Diseases; Cocarcinogenesis; DNA, Vira

1992
Incidence of neoplasms in patients with rheumatoid arthritis exposed to different treatment regimens.
    The American journal of medicine, 1985, Jan-21, Volume: 78, Issue:1A

    Topics: Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; Cystitis; Humans; Immunosuppres

1985
Incidence of cancer in rheumatoid arthritis and other disorders after immunosuppressive treatment.
    The American journal of medicine, 1985, Jan-21, Volume: 78, Issue:1A

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squa

1985
Malignant tumours following immunosuppression in renal transplantation.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1973, Volume: 10, Issue:0

    Topics: Adenocarcinoma; Adult; Azathioprine; Brain Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinom

1973
Carcinoma of the bladder in a renal transplant patient.
    The Journal of urology, 1973, Volume: 109, Issue:3

    Topics: Azathioprine; Carcinoma, Transitional Cell; Cystoscopy; Kidney Transplantation; Prednisone; Transpla

1973
Disseminated visceral Kaposi's sarcoma. Appearance after human renal homograft operation.
    JAMA, 1969, Feb-24, Volume: 207, Issue:8

    Topics: Adult; Azathioprine; Esophageal Neoplasms; Female; Humans; Kidney Transplantation; Lung Neoplasms; M

1969