Page last updated: 2024-10-23

azathioprine and Ureteral Obstruction

azathioprine has been researched along with Ureteral Obstruction in 9 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Ureteral Obstruction: Blockage in any part of the URETER causing obstruction of urine flow from the kidney to the URINARY BLADDER. The obstruction may be congenital, acquired, unilateral, bilateral, complete, partial, acute, or chronic. Depending on the degree and duration of the obstruction, clinical features vary greatly such as HYDRONEPHROSIS and obstructive nephropathy.

Research Excerpts

ExcerptRelevanceReference
"Azathioprine was then considered as an alternative treatment."5.27Azathioprine. An alternative treatment for recurrent idiopathic retroperitoneal fibrosis. ( Cogan, E; Fastrez, R, 1985)
"The effect of mycophenolate mofetil (MMF) and azathioprine (AZA) in reducing renal interstitial fibrosis in rats with unilateral ureteral obstruction (UUO) was studied."3.72Comparison of mycophenolate mofetil and azathioprine in obstructive nephropathy. ( Anarat, A; Bayazit, AK; Bayazit, Y; Gonlusen, G; Noyan, A, 2003)
"Retroperitoneal fibrosis is a severe disease that affects the ureters, causing renal insufficiency in three-quarters of patients."1.33Long-term outcome of idiopathic retroperitoneal fibrosis treated with surgical and/or medical approaches. ( Banfi, G; Gallelli, B; Messa, P; Moroni, G; Ponticelli, C; Sandri, S, 2006)
"Azathioprine was then considered as an alternative treatment."1.27Azathioprine. An alternative treatment for recurrent idiopathic retroperitoneal fibrosis. ( Cogan, E; Fastrez, R, 1985)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bayazit, AK1
Bayazit, Y1
Noyan, A1
Gonlusen, G1
Anarat, A1
STARZL, TE1
MARCHIORO, TL1
PORTER, KA1
MOORE, CA1
RIFKIND, D1
WADDELL, WR1
Moroni, G1
Gallelli, B1
Banfi, G1
Sandri, S1
Messa, P1
Ponticelli, C1
Light, JA1
Biggers, JA1
Alijani, MR1
Smith, M1
Oddendino, K1
Harreby, M1
Bilde, T1
Helin, P1
Meyhoff, HH1
Vinterberg, H1
Nielsen, VA1
Cogan, E1
Fastrez, R1
Fine, RN1
Mahon, FB1
Malek, GH1
Uehling, DT1
Munro, A1
Bewick, M1
Manuel, L1
Cameron, JS1
Ellis, FG1
Boulton-Jones, M1
Ogg, CS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomised Trial of Prednisone and Tamoxifen in Patients With Idiopathic Retroperitoneal Fibrosis[NCT00440349]Phase 238 participants Interventional2000-10-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for azathioprine and Ureteral Obstruction

ArticleYear
Comparison of mycophenolate mofetil and azathioprine in obstructive nephropathy.
    Pediatric nephrology (Berlin, Germany), 2003, Volume: 18, Issue:2

    Topics: Animals; Azathioprine; Collagen; Fibronectins; Fibrosis; Immunohistochemistry; Kidney Diseases; Myco

2003
RENAL HOMOTRANSPLANTATION; LATE FUNCTION AND COMPLICATIONS.
    Annals of internal medicine, 1964, Volume: 61

    Topics: Adolescent; Azathioprine; Blood Pressure; Blood Pressure Determination; Blood Urea Nitrogen; Child;

1964
Long-term outcome of idiopathic retroperitoneal fibrosis treated with surgical and/or medical approaches.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Azathioprine; Female; Follow-Up Studies; Glucocorticoi

2006
Serum beta-2-microglobulin: an adjunctive monitoring test in renal transplantation.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1980, Volume: 10

    Topics: Antilymphocyte Serum; Azathioprine; beta 2-Microglobulin; Beta-Globulins; Creatinine; Graft Rejectio

1980
Retroperitoneal fibrosis treated with methylprednisolon pulse and disease-modifying antirheumatic drugs.
    Scandinavian journal of urology and nephrology, 1994, Volume: 28, Issue:3

    Topics: Adult; Azathioprine; Combined Modality Therapy; Drug Therapy, Combination; Female; Follow-Up Studies

1994
Azathioprine. An alternative treatment for recurrent idiopathic retroperitoneal fibrosis.
    Archives of internal medicine, 1985, Volume: 145, Issue:4

    Topics: Azathioprine; Blood Sedimentation; Creatinine; Humans; Hydronephrosis; Male; Middle Aged; Prednisone

1985
Renal transplantation in children.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1972, Volume: 9

    Topics: Adolescent; Adult; Azathioprine; Bone Development; Bone Diseases; Candidiasis; Child; Child, Prescho

1972
Urinary tract infection after renal transplantation.
    Urology, 1973, Volume: 1, Issue:6

    Topics: Adolescent; Adult; Ampicillin; Azathioprine; Bacteriuria; Cadaver; Female; Glomerulonephritis; Human

1973
Clinical evaluation of a rosette inhibition test in renal allotransplantation.
    British medical journal, 1971, Jul-31, Volume: 3, Issue:5769

    Topics: Animals; Antigen-Antibody Reactions; Antigens; Antilymphocyte Serum; Anuria; Azathioprine; Diagnosis

1971