Page last updated: 2024-10-23

azathioprine and Uremia

azathioprine has been researched along with Uremia in 60 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
"Only patients with labile IDDM (e."2.68Solitary pancreas transplantation for nonuremic patients with labile insulin-dependent diabetes mellitus. ( Dunn, DL; Gruessner, AC; Gruessner, RW; Najarian, JS; Sutherland, DE, 1997)
" That preuremic transplantation is safe and efficacious in patients with immanent end-stage renal disease has not been established."1.27Renal transplantation done safely without prior chronic dialysis therapy. ( Ascher, NL; Fryd, D; Migliori, RJ; Najarian, JS; Payne, WD; Simmons, RL; Sutherland, DE, 1987)

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-199051 (85.00)18.7374
1990's7 (11.67)18.2507
2000's2 (3.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Odlind, B2
Hartvig, P2
Lindström, B2
Lönnerholm, G2
Tufveson, G1
Grefberg, N2
Koyun, M1
Baysal, YE1
Usta, MF1
Akman, S1
Güven, AG1
STARZL, TE3
MARCHIORO, TL2
DICKINSON, TC1
RIFKIND, D2
STONINGTON, OG1
WADDELL, WR2
KIRKPATRICK, CH3
WILSON, WE3
TALMAGE, DW2
HITCHCOCK, CR2
KISER, JC1
TELANDER, RL1
SELJESKOG, EL1
PETERS, GN1
PORTER, KA1
OGDEN, DA2
SITPRIJA, V1
HOLMES, JH1
ROENIGK, HH1
HASERICK, JR1
NAKAMOTO, S1
MCCORMACK, LJ1
Finco, DR1
Barsanti, JA1
Rawlings, CA1
Miller, TE1
Ormrod, DJ1
Wilson, DM1
Kokot, F1
Cariem, AK1
Arendse, M1
Cruse, P1
Rayner, B1
Malyszko, JS1
Malyszko, J1
Pawlak, K1
Mysliwiec, M1
Takada, Y1
Takada, A1
Gruessner, RW1
Sutherland, DE2
Najarian, JS2
Dunn, DL1
Gruessner, AC1
Weyer, N1
Kröplin, T1
Fricke, L1
Iven, H1
Maddocks, JL1
Baumgarten, SR1
Lindsay, GK1
Wise, GJ1
Dupont, E1
Quadracci, LJ1
Ringdén, O2
Krzymanski, M1
Van den Bergh, FA1
Rietra, PJ1
Kolk-Vegter, AJ1
Bosch, E1
Tager, JM1
Nelson, DS1
Penrose, JM1
Friedman, EA1
Ginzler, E1
Hibbins, M1
Chapman, JR1
Cantarovich, D1
Dantal, J1
Hourmant, M1
Baatard, R1
Paineau, J1
Murat, A1
Soulillou, JP1
Chocair, PR1
Duley, JA1
Simmonds, HA1
Cameron, JS2
Klinger, M1
Słowik, E1
Kopeć, W1
Szewczyk, Z1
Groth, CG2
Fehrman, I1
Lundgren, G1
Müller, C1
Schernthaner, G1
Kovarik, J1
Kalinowska, W1
Zielinski, CC1
Migliori, RJ1
Simmons, RL1
Payne, WD1
Ascher, NL1
Fryd, D1
Myers, BD1
Frödin, L1
Backman, U1
Waterhouse, C1
Abraham, G1
Vaughan, J1
Epstein, WV1
Gulyassy, PF1
Tan, M1
Rae, AI1
Sengar, DP1
Rashid, A1
Harris, JE1
Saenger, P1
Wiedemann, E1
Schwartz, E1
Korth-Schutz, S1
Lewy, JE1
Riggio, RR1
Rubin, AL1
Stenzel, KH1
New, MI1
Cerilli, GJ1
Nelsen, C1
Dorfmann, L1
Nichols, G1
Flanagan, B1
van der Sluys Veer, J1
Johnson, JW1
Hampers, CL1
Merrill, JP1
Penn, I1
Durst, AL1
Machado, M1
Halgrimson, CG1
Booth, AS1
Putman, CW1
Souhami, RL1
Smith, J1
Bradfield, JW1
Wellman, MR1
Miller, DR1
Storm, B2
Lindholm, A1
Varkarakis, MJ1
Bhanalaph, T1
Murphy, GP1
Montorsi, W1
Ganner, E1
Osment, J1
Dittrich, P1
Huber, H1
Jenkins, JD2
Stahl, WM2
Phadke, AG1
MacKinnon, KJ1
Dossetor, JB1
Weeke, E2
Andersen, V2
Sorensen, SF2
Bahr, B2
Cagli, V1
Daniels, JC1
Sakai, H1
Fish, JC1
Lindley, JD1
Remmers, AR1
Sarles, HE1
Tyson, KR1
Ritzmann, SE1
Munro, A1
Bewick, M1
Manuel, L1
Ellis, FG1
Boulton-Jones, M1
Ogg, CS1
Luke, RG1
Koepke, JA1
Siegel, RR1
Orlowski, T1
Nielubowicz, J1
Gradowska, L1
Rowiński, W1
Klopotowska, E1
Casey, TP1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Conversion of Calcineurin-Inhibitors(Tacrolimus to Sirolimus),6-24 Months Post Transplant Prednisone-Free Immunosuppression Regimen: Impact of Incidence of Acute Cellular Rejection,Renal Allograft Function & Lymphocytes Function[NCT00866879]Phase 4275 participants (Actual)Interventional2007-06-30Completed
Genetic Predisposition of Chronic Nephrotoxicity From Calcineurin Inhibitors in Liver Transplant Recipients, Potential Correlation With Urinary Biomarkers[NCT00857844]207 participants (Actual)Observational2007-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Incidence of Acute Cellular Rejection

The primary purpose of this research study is to evaluate whether the use of mycophenolate mofetil/Cellcept ® and either tacrolimus/Prograf ® (Group #1) or mycophenolate mofetil/Cellcept ® and sirolimus/Rapamune® (Group #2) impacts the incidence of acute cellular rejection in post-kidney transplant patients. This study will examine whether switching from tacrolimus to sirolimus will better preserve long-term kidney function. (NCT00866879)
Timeframe: Assessed at 6 Months, 12 Months, 24 Months, months 24 reported

InterventionParticipants (Count of Participants)
Control7
Transition to Sirolimus Group31

Percentage of Regulatory T Cells

"Specifically we reported here the percentage of regulatory T cells that were present in the two groups at 24 months post randomization.~With peripheral leukocytes taken at baseline (first visit) prior to randomization and at 6, 12 and 24 Months post-randomization, researchers will also review possible modifications of lymphocytes function and of the lymphocytes subpopulations that might have occurred as a consequence of the switch from tacrolimus to sirolimus (randomization)." (NCT00866879)
Timeframe: Assessed at 6 Months, 12 Months, 24 Months, months 24 reported

Intervention% of Treg Cells (Mean)
Control75
Transition to Sirolimus Group98

Renal Allograft Function Calculated With e-GFR and Proteinuria

Evaluate whether CI conversion (tacrolimus→sirolimus) contributes positively or negatively on the renal allograft function calculated with e-GFR and proteinuria (NCT00866879)
Timeframe: Assessed at 6 Months, 12 Months, 24 Months, months 24 reported

InterventionmL/min (Mean)
Control57.6
Transition to Sirolimus Group58.4

Evaluate if CI Conversion Impacts on Lipid Profile, Incidence of Hypertension, Malignancies, and Opportunistic Infections and Post-transplant DM

In addition to monitoring renal allograft function, evaluation will be conducted on the incidence of acute rejection, patient and graft survival, the impact of CI conversion on the lipid profile, the incidence of hypertension, malignancies, opportunistic infections and post-transplant DM (de novo diabetes mellitus). (NCT00866879)
Timeframe: Assessed at 6 Months, 12 Months, 24 Months, months 24 reported

,
Interventionnumber of incidents (Number)
InfectionsMalignanciesProteinuraHyperlipidemiaNODATBK viremiaBK nephropathyNeutropenia
Control334129315122
Transition to Sirolimus Group8396119228535

Patient and Graft Survival

This study also reviews the impact of the immunosuppressive medications on patient and graft survival. (NCT00866879)
Timeframe: Assessed at 6 Months, 12 Months, 24 Months, months 24 reported

,
Interventionnumber of incidents (Number)
Kidney transplant lossPatient death
Control43
Transition to Sirolimus Group1210

Reviews

3 reviews available for azathioprine and Uremia

ArticleYear
Extracapillary (crescenteric) glomerulonephritis.
    Acta medica Scandinavica, 1975, Volume: 198, Issue:3

    Topics: Anticoagulants; Azathioprine; Capillaries; Cell Division; Diagnosis, Differential; Glomerulonephriti

1975
Cyclosporine nephrotoxicity.
    Kidney international, 1986, Volume: 30, Issue:6

    Topics: Acute Kidney Injury; Adult; Azathioprine; Creatine; Cyclosporins; Glomerular Filtration Rate; Glomer

1986
Cyclosporine nephrotoxicity.
    Kidney international, 1986, Volume: 30, Issue:6

    Topics: Acute Kidney Injury; Adult; Azathioprine; Creatine; Cyclosporins; Glomerular Filtration Rate; Glomer

1986
Cyclosporine nephrotoxicity.
    Kidney international, 1986, Volume: 30, Issue:6

    Topics: Acute Kidney Injury; Adult; Azathioprine; Creatine; Cyclosporins; Glomerular Filtration Rate; Glomer

1986
Cyclosporine nephrotoxicity.
    Kidney international, 1986, Volume: 30, Issue:6

    Topics: Acute Kidney Injury; Adult; Azathioprine; Creatine; Cyclosporins; Glomerular Filtration Rate; Glomer

1986
[Course and prognosis of glomerulonephritis].
    Il Policlinico. Sezione pratica, 1970, Oct-05, Volume: 77, Issue:40

    Topics: Acute Disease; Age Factors; Anti-Bacterial Agents; Anti-Glomerular Basement Membrane Disease; Antige

1970

Trials

3 trials available for azathioprine and Uremia

ArticleYear
Solitary pancreas transplantation for nonuremic patients with labile insulin-dependent diabetes mellitus.
    Transplantation, 1997, Dec-15, Volume: 64, Issue:11

    Topics: Adolescent; Adult; Azathioprine; Cyclosporine; Diabetes Mellitus, Type 1; Female; Graft Rejection; G

1997
Human thiopurine S-methyltransferase activity in uremia and after renal transplantation.
    European journal of clinical pharmacology, 2001, Volume: 57, Issue:2

    Topics: Adult; Aged; Azathioprine; Chromatography, High Pressure Liquid; Female; Humans; Immunosuppressive A

2001
Activity of type 1 erythrocyte complement receptors in uremia and after renal transplantation.
    The International journal of artificial organs, 1990, Volume: 13, Issue:10

    Topics: Adult; Azathioprine; Cyclosporins; Erythrocytes; Female; Humans; Immune Adherence Reaction; Immunosu

1990

Other Studies

54 other studies available for azathioprine and Uremia

ArticleYear
Serum azathioprine and 6-mercaptopurine levels and immunosuppressive activity after azathioprine in uremic patients.
    International journal of immunopharmacology, 1986, Volume: 8, Issue:1

    Topics: Administration, Oral; Adult; Azathioprine; Erythrocytes; Female; Humans; Immune Tolerance; Injection

1986
Evaluation of reproductive functions in male adolescents following renal transplantation.
    Pediatric transplantation, 2009, Volume: 13, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Azathioprine; Cyclosporine; Follicle Stimulating Hormone; Human

2009
TECHNIQUE OF RENAL HOMOTRANSPLANTATION. EXPERIENCE WITH 42 CASES.
    Archives of surgery (Chicago, Ill. : 1960), 1964, Volume: 89

    Topics: Azathioprine; Dactinomycin; Diabetes Mellitus; Gastrointestinal Hemorrhage; Humans; Intestinal Obstr

1964
IMMUNOLOGIC STUDIES IN HUMAN ORGAN TRANSPLANTATION. I. OBSERVATION AND CHARACTERIZATION OF SUPPRESSED CUTANEOUS REACTIVITY IN UREMIA.
    The Journal of experimental medicine, 1964, May-01, Volume: 119

    Topics: Adrenal Cortex Hormones; Antigen-Antibody Reactions; Antigens; Azathioprine; Candida; Glomerulonephr

1964
BABOON RENAL GRAFTS.
    JAMA, 1964, Sep-21, Volume: 189

    Topics: Allergy and Immunology; Animals; Azathioprine; Blood Chemical Analysis; Blood Group Antigens; Dextra

1964
RENAL HETEROTRANSPLANTATION FROM BABOON TO MAN: EXPERIENCE WITH 6 CASES.
    Transplantation, 1964, Volume: 2

    Topics: Animals; Antibodies; Azathioprine; Biomedical Research; Blood Group Antigens; Dactinomycin; Drug The

1964
IMMUNOLOGIC STUDIES IN HUMAN ORGAN TRANSPLANTATION. 3. THE RELATIONSHIP OF DELAYED CUTANEOUS HYPERSENSITIVITY TO THE ONSET OF ATTEMPTED KIDNEY ALLOGRAFT REJECTION.
    The Journal of clinical investigation, 1964, Volume: 43

    Topics: Adolescent; Allografts; Antigen-Antibody Reactions; Azathioprine; Child; Dactinomycin; Drug Therapy;

1964
FUNCTION OF THE BABOON RENAL HETEROGRAFT IN MAN AND COMPARISON WITH RENAL HOMOGRAFT FUNCTION.
    The Journal of laboratory and clinical medicine, 1965, Volume: 65

    Topics: Allografts; Animals; Azathioprine; Biomedical Research; Blood Urea Nitrogen; Chlorides; Creatine; Cr

1965
SYSTEMIC LUPUS ERYTHEMATOSUS AND RENAL TRANSPLANTATION: REPORT OF TWO CASES.
    Archives of dermatology, 1965, Volume: 92

    Topics: Adolescent; Azathioprine; Humans; Kidney; Kidney Transplantation; Kidneys, Artificial; Leukopenia; L

1965
Effect of immunosuppressive drug therapy on blood urea nitrogen concentration in dogs with azotemia.
    Journal of the American Veterinary Medical Association, 1984, Sep-15, Volume: 185, Issue:6

    Topics: Animals; Azathioprine; Blood Urea Nitrogen; Creatinine; Dog Diseases; Dogs; Female; Kidney Failure,

1984
Pharmacokinetics of azathioprine and 6-mercaptopurine: methodological aspects and preliminary results in uremic patients.
    Scandinavian journal of urology and nephrology. Supplementum, 1981, Volume: 64

    Topics: Administration, Oral; Animals; Azathioprine; Dogs; Erythrocytes; Freezing; Half-Life; Humans; Kidney

1981
Synergism between immunosuppressive agents and uremia?
    Infection and immunity, 1982, Volume: 38, Issue:2

    Topics: Animals; Antibody Formation; Azathioprine; Cyclophosphamide; Female; Immunosuppressive Agents; Metho

1982
[Use of immunosuppresive agents in the treatment of kidney diseases. Drug therapy of uremia and kidney calculi].
    Przeglad lekarski, 1982, Volume: 39, Issue:7

    Topics: Allopurinol; Azathioprine; Benzothiadiazines; Cyclophosphamide; Diuretics; Glucocorticoids; Humans;

1982
A 34-year-old man with recurrent melaena after renal transplantation.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1996, Volume: 86, Issue:10

    Topics: Adult; Azathioprine; Diagnosis, Differential; Gastrointestinal Hemorrhage; Humans; Immunosuppressive

1996
Effects of azathioprine and mizoribine on aggregation of normal and uremic platelets.
    Transplantation proceedings, 1996, Volume: 28, Issue:6

    Topics: Adenosine Diphosphate; Arachidonic Acid; Azathioprine; Collagen; Humans; Immunosuppressive Agents; I

1996
Assay of azathioprine, 6-mercaptopurine and a novel thiopurine metabolite in human plasma.
    British journal of clinical pharmacology, 1979, Volume: 8, Issue:3

    Topics: Azathioprine; Chemical Phenomena; Chemistry; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kidney

1979
Fertility problems in the renal transplant patient.
    The Journal of urology, 1977, Volume: 118, Issue:6

    Topics: Adult; Azathioprine; Follicle Stimulating Hormone; Humans; Infertility, Male; Kidney; Kidney Transpl

1977
Assessment of whole blood for antibody-dependent cell-mediated cytotoxicity in kidney patients.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1977, Volume: 14

    Topics: Antibodies; Antibody-Dependent Cell Cytotoxicity; Azathioprine; Cytotoxicity Tests, Immunologic; Gra

1977
The effect of uremia and transplantation on lymphocyte subpopulations.
    Kidney international, 1976, Volume: 10, Issue:2

    Topics: Antibody Formation; Azathioprine; B-Lymphocytes; Chronic Disease; Humans; Immunity, Cellular; Kidney

1976
B.C.P. Jansen Institute, University of Amsterdam, Amsterdam, The Netherlands.
    Acta medica Scandinavica, 1976, Volume: 200, Issue:4

    Topics: Adult; Azathioprine; Ceramides; Cerebrosides; Fabry Disease; Follow-Up Studies; Galactosidases; Glyc

1976
Effect of hemodialysis and transplantation on inhibition of lymphocyte transformation by sera from uremic patients.
    Clinical immunology and immunopathology, 1975, Volume: 4, Issue:1

    Topics: Azathioprine; Cells, Cultured; Glucocorticoids; Humans; Immune Sera; Immunosuppression Therapy; Kidn

1975
Strategy for lupus nephritis.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1975, Volume: 5

    Topics: Azathioprine; Biopsy; Cyclophosphamide; Drug Therapy, Combination; Humans; Kidney; Lupus Erythematos

1975
In vitro assessment of triple-therapy immunosuppression and prostaglandin analogues enisoprost and misoprostol.
    Transplantation proceedings, 1992, Volume: 24, Issue:1

    Topics: Alprostadil; Azathioprine; Cells, Cultured; Cyclosporine; Drug Interactions; Drug Synergism; Female;

1992
Importance of cyclosporine dosage and blood levels in simultaneous pancreas and kidney transplant success.
    Transplantation proceedings, 1992, Volume: 24, Issue:3

    Topics: Adult; Antibodies, Monoclonal; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diabetes Mellitus,

1992
Thiopurine methyltransferase activity and efficacy of azathioprine immunosuppression in transplant recipients.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: Adult; Azathioprine; Cyclosporine; Erythrocytes; Female; Humans; Kidney Transplantation; Leukopenia;

1991
Related donor kidney transplantation is the best form of treatment for uremia.
    Transplantation proceedings, 1987, Volume: 19, Issue:1 Pt 3

    Topics: Adolescent; Adult; Azathioprine; Blood Transfusion; Child; Cyclosporins; Family; Follow-Up Studies;

1987
Natural killer cell activity and antibody-dependent cellular cytotoxicity in patients under various immunosuppressive regimens.
    Clinical immunology and immunopathology, 1987, Volume: 44, Issue:1

    Topics: Antibody-Dependent Cell Cytotoxicity; Antilymphocyte Serum; Azathioprine; Cyclosporins; Drug Synergi

1987
Renal transplantation done safely without prior chronic dialysis therapy.
    Transplantation, 1987, Volume: 43, Issue:1

    Topics: Azathioprine; Cyclosporins; Graft Survival; HLA Antigens; Humans; Kidney; Kidney Failure, Chronic; K

1987
Renal transplantation in Uppsala.
    Upsala journal of medical sciences, 1985, Volume: 90, Issue:2

    Topics: Azathioprine; Cyclosporins; Graft Survival; History, 20th Century; Hospitals, University; Humans; Ki

1985
The relationship between L-chain synthesis and gamma-globulin production.
    The Journal of clinical investigation, 1973, Volume: 52, Issue:5

    Topics: Adult; Aged; Antibody Formation; Azathioprine; Female; gamma-Globulins; Humans; Immunoglobulin Fragm

1973
Effect of renal hemotransplantation on the metabolism of the light chains of immunoglobulins.
    Annals of internal medicine, 1968, Volume: 68, Issue:1

    Topics: Adolescent; Adult; Azathioprine; Child; Creatinine; gamma-Globulins; Humans; Kidney Failure, Chronic

1968
In vitro cellular immunity and in vivo delayed hypersensitivity in uremic patients maintained on hemodialysis.
    International archives of allergy and applied immunology, 1974, Volume: 47, Issue:6

    Topics: Azathioprine; Female; Glomerulonephritis; Graft Rejection; Humans; Hypersensitivity, Delayed; Immuni

1974
Somatomedin and growth after renal transplantation.
    Pediatric research, 1974, Volume: 8, Issue:3

    Topics: Adolescent; Age Determination by Skeleton; Azathioprine; Body Height; Bone Development; Child; Gluco

1974
Renal homotransplantation in infants and children with the hemolytic-uremic syndrome.
    Surgery, 1972, Volume: 71, Issue:1

    Topics: Anemia, Hemolytic; Antilymphocyte Serum; Azathioprine; Blood Urea Nitrogen; Cadaver; Child; Creatini

1972
Metabolic studies of bone in uremia before and after treatment.
    Metabolism: clinical and experimental, 1972, Volume: 21, Issue:4

    Topics: Adult; Azathioprine; Bone and Bones; Bone Resorption; Carbon Isotopes; Chronic Kidney Disease-Minera

1972
Acute pancreatitis and hyperamylasemia in renal homograft recipients.
    Archives of surgery (Chicago, Ill. : 1960), 1972, Volume: 105, Issue:2

    Topics: Adolescent; Adult; Amylases; Azathioprine; Calcium; Cholelithiasis; Creatinine; Female; Humans; Hype

1972
The effect of uraemia on organ graft survival in the rat.
    British journal of experimental pathology, 1973, Volume: 54, Issue:2

    Topics: Adrenal Gland Diseases; Adrenal Glands; Animals; Azathioprine; Disease Models, Animal; Graft Rejecti

1973
The nitroblue-tetrazolium dye test and infection in the renal patient.
    American heart journal, 1973, Volume: 86, Issue:2

    Topics: Azathioprine; Bacterial Infections; Coloring Agents; Diagnosis, Differential; Graft Rejection; Human

1973
Graft and patient survival after primary cadaver kidney transplantation with special regard to compatibility in the HL-A system.
    Acta chirurgica Scandinavica. Supplementum, 1973, Volume: 437

    Topics: Adult; Azathioprine; Biopsy; Cadaver; Female; Follow-Up Studies; Graft Rejection; Histocompatibility

1973
The influence of histocompatibility on graft and patient survival in primary cadaver kidney transplantation.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1972, Volume: 9

    Topics: Age Factors; Azathioprine; Cadaver; Cytotoxicity Tests, Immunologic; Graft Rejection; Histocompatibi

1972
Effect of estrogens on canine renal allografts.
    Urology, 1974, Volume: 3, Issue:2

    Topics: Animals; Azathioprine; Blood Urea Nitrogen; Capillary Permeability; Dogs; Drug Synergism; Edema; Est

1974
[The kidney transplant].
    Minerva medica, 1974, Jan-31, Volume: 65, Issue:7

    Topics: Acute Kidney Injury; Animals; Antilymphocyte Serum; Azathioprine; Graft Rejection; Humans; Kidney Di

1974
Chromosomes in patients treated with azathioprine.
    Humangenetik, 1973, May-25, Volume: 18, Issue:3

    Topics: Adult; Azathioprine; Bone Marrow Cells; Cells, Cultured; Chromatids; Chromosome Aberrations; Chromos

1973
Lymphocyte trapping in dog popliteal lymph nodes: the influence of acute uremia and pharmacologic immunosuppression.
    Annals of surgery, 1968, Volume: 167, Issue:1

    Topics: Animals; Azathioprine; Chromium Isotopes; Dogs; Lymph Nodes; Lymphocytes; Mesentery; Skin Transplant

1968
Lymphocyte trapping by lymph nodes: normal physiology and effects of uremia and immunosuppression.
    Surgical forum, 1967, Volume: 18

    Topics: Animals; Azathioprine; Dogs; Lymph Nodes; Lymphocytes; Radioisotopes; Skin Transplantation; Transpla

1967
Male fertility in uremia: restoration by renal allografts.
    Canadian Medical Association journal, 1970, Mar-28, Volume: 102, Issue:6

    Topics: Adolescent; Adult; Azathioprine; Biopsy; Female; Fertility; Humans; Kidney Failure, Chronic; Kidney

1970
Extracorporeal irradiation of the blood as immunosuppressive treatment in renal ansplantation.
    Acta medica Scandinavica, 1970, Mar-03, Volume: 187, Issue:3

    Topics: Adult; Azathioprine; Blood; Extracorporeal Circulation; Female; Humans; Kidney Transplantation; Lymp

1970
[Extracorporeal irradiation of the blood. II. Immunosuppressive treatment in kidney transplantation].
    Ugeskrift for laeger, 1970, Mar-19, Volume: 132, Issue:12

    Topics: Adult; Azathioprine; Blood; Extracorporeal Circulation; Female; Humans; Immunosuppressive Agents; Ki

1970
Surgical Grand Rounds from the University of Mississippi Medical Center. Renal transplantation.
    Southern medical journal, 1971, Volume: 64, Issue:7

    Topics: Adult; Azathioprine; Consanguinity; Heart Failure; Humans; Hypertension, Malignant; Kidney Transplan

1971
The conversion phenomenon of uremic lymphocytes: mechanisms of nucleic acid kinetics.
    Journal of the Reticuloendothelial Society, 1971, Volume: 9, Issue:5

    Topics: Adolescent; Adult; Azathioprine; DNA; Female; Humans; Immunosuppression Therapy; Kidney Transplantat

1971
Clinical evaluation of a rosette inhibition test in renal allotransplantation.
    British medical journal, 1971, Jul-31, Volume: 3, Issue:5769

    Topics: Animals; Antigen-Antibody Reactions; Antigens; Antilymphocyte Serum; Anuria; Azathioprine; Diagnosis

1971
The effects of immunosuppressive drugs and uremia on automated leukocyte counts.
    American journal of clinical pathology, 1971, Volume: 56, Issue:4

    Topics: Adult; Autoanalysis; Azathioprine; Blood Urea Nitrogen; Creatinine; Erythrocyte Count; Female; Human

1971
Function of a transplanted kidney.
    Polish medical journal, 1967, Volume: 6, Issue:2

    Topics: Adult; Azathioprine; Body Weight; Female; Glomerulonephritis; Humans; Immune Tolerance; Kidney; Kidn

1967
The development of lymphomas in mice with autoimmune disorders treated with azathioprine.
    Blood, 1968, Volume: 31, Issue:3

    Topics: Animals; Autoimmune Diseases; Azathioprine; Female; Injections, Intramuscular; Lupus Erythematosus,

1968