Page last updated: 2024-10-23

azathioprine and Ulcer

azathioprine has been researched along with Ulcer in 24 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.

Research Excerpts

ExcerptRelevanceReference
"A 16-year-old woman with MG developed hair loss, pancytopenia, bloody diarrhea, and fever shortly after azathioprine treatment."8.12Alopecia and colon ulcers following azathioprine use in a patient with myasthenia gravis: A case report. ( Hsu, WY; Lin, LC; Lin, PC; Liu, YC, 2022)
"A retrospective review of the literature has been carried out to determine laboratory abnormalities occurring in patients with rheumatoid arthritis (RA) treated with azathioprine, in order to establish a profile for this agent in the treatment of this disease."7.66Rheumatoid arthritis: treatment with azathioprine (IMURAN (R)). Clinical side-effects and laboratory abnormalities. ( Pelkey, J; Whisnant, JK, 1982)
"Simple ulcer is clinically and pathologically recognized as a serious disease linked to intestinal Behcet's disease."5.31A child with simple ulcer of the colon effectively treated with the combination of prednisolone, azathioprine, and pentoxifylline. ( Kasahara, E; Tanaka, M; Yamagishi, N; Yashiro, K, 2002)
"A 16-year-old woman with MG developed hair loss, pancytopenia, bloody diarrhea, and fever shortly after azathioprine treatment."4.12Alopecia and colon ulcers following azathioprine use in a patient with myasthenia gravis: A case report. ( Hsu, WY; Lin, LC; Lin, PC; Liu, YC, 2022)
"A retrospective review of the literature has been carried out to determine laboratory abnormalities occurring in patients with rheumatoid arthritis (RA) treated with azathioprine, in order to establish a profile for this agent in the treatment of this disease."3.66Rheumatoid arthritis: treatment with azathioprine (IMURAN (R)). Clinical side-effects and laboratory abnormalities. ( Pelkey, J; Whisnant, JK, 1982)
"It is important to distinguish between ulcerative colitis and Crohn's colitis because response to treatment and prognosis are different."2.35Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis. ( Ament, ME, 1975)
"Azathioprine was added to her regimen due to lack of response; however, despite 6 weeks of this therapy, the ulcerations did not heal thus infliximab was initiated."1.91Successful multidisciplinary treatment of the rare pathology of vulvar Crohn's disease. ( Al Yacoub, R; Brown, K; Ladna, M, 2023)
"A 71-year-old man developed ulcerative colitis (UC) at 48 years of age."1.72[A case of "colitis-like intestinal Behçet's disease" accompanied by ulcerative colitis after the development of myelodysplastic syndrome]. ( Hara, E; Kamakura, M; Kitabatake, H; Kondo, S; Kunimoto, H; Nakamura, A; Ochi, Y; Saito, H; Seki, A, 2022)
"During the follow-up period, cumulative recurrence rates for intestinal BD were 24."1.36Response rates to medical treatments and long-term clinical outcomes of nonsurgical patients with intestinal Behçet disease. ( Cheon, JH; Chung, MJ; Kim, NK; Kim, SU; Kim, TI; Kim, WH; Park, JJ, 2010)
"Lipodystrophy was seen in 10/33 (30."1.33Twelve years experience of juvenile dermatomyositis in North India. ( Bansal, A; Singh, S, 2006)
"Simple ulcer is clinically and pathologically recognized as a serious disease linked to intestinal Behcet's disease."1.31A child with simple ulcer of the colon effectively treated with the combination of prednisolone, azathioprine, and pentoxifylline. ( Kasahara, E; Tanaka, M; Yamagishi, N; Yashiro, K, 2002)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19906 (25.00)18.7374
1990's4 (16.67)18.2507
2000's5 (20.83)29.6817
2010's6 (25.00)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Kondo, S1
Kamakura, M1
Nakamura, A1
Saito, H1
Kunimoto, H1
Kitabatake, H1
Seki, A1
Ochi, Y1
Hara, E1
Hsu, WY1
Lin, PC1
Liu, YC1
Lin, LC1
Al Yacoub, R1
Brown, K1
Ladna, M1
Cunningham, F1
Darling, MI1
Gangopadhyay, M1
Jackson, R1
McKay, P1
Bilsland, D1
Kijmassuwan, T1
Tanpowpong, P1
Molagool, S1
Treepongkaruna, S1
Nordstrom, E1
Fischer, M1
Koçak, G1
Koçak, E1
Akbal, E1
Şen, H1
Erbağ, G1
Erdoğan, C1
Calderón, FM1
Valladares, VG1
Ballesteros, AM1
de la Merced Ayala, MC1
Chung, MJ1
Cheon, JH1
Kim, SU1
Park, JJ1
Kim, TI1
Kim, NK1
Kim, WH1
Murakami, Y1
Matsui, T1
Hirai, F1
Takatsu, N1
Takaki, Y1
Nagahama, T1
Hisabe, T1
Beppu, T1
Miyaoka, M1
Maki, S1
Takeichi, M1
Nishimura, T1
Ueki, T1
Yao, K1
Kasahara, E1
Yamagishi, N1
Tanaka, M1
Yashiro, K1
Akbulut, S1
Yavuz, B1
Köseoğlu, T1
Gököz, A1
Saritaş, U1
Ono, M1
Murakami, K1
Oda, M1
Miyajima, H1
Watanabe, K1
Sato, R1
Nasu, M1
Kashima, K1
Singh, S1
Bansal, A1
McCarthy, CF1
Whisnant, JK1
Pelkey, J1
Farthing, PM1
Maragou, P1
Coates, M1
Tatnall, F1
Leigh, IM1
Williams, DM1
Smak Gregoor, PJ1
van Saase, JL1
vd Ingh, HF1
Weimar, W1
Kramer, P1
Enns, R1
Lay, T1
Bridges, R1
Hafeez, ZH1
Ament, ME1
Stuart, FP1
Torres, E1
Moore, FD1
Sutherland, D1
Frech, RS1
Weil, R1
Najarian, JS1
Simmons, RL1
Bell, MJ1
Martin, LW1
Gonzales, LL1
McEnery, PT1
West, CD1

Reviews

2 reviews available for azathioprine and Ulcer

ArticleYear
[A case of simple ulcer with ulcerative colitis].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2005, Volume: 102, Issue:7

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Behcet Syndrome; Cecal Diseases; Colit

2005
Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis.
    The Journal of pediatrics, 1975, Volume: 86, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Anus Diseases; Arthritis; Azathioprine; Child, Preschool; Colectomy;

1975

Other Studies

22 other studies available for azathioprine and Ulcer

ArticleYear
[A case of "colitis-like intestinal Behçet's disease" accompanied by ulcerative colitis after the development of myelodysplastic syndrome].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2022, Volume: 119, Issue:6

    Topics: Aged; Azathioprine; Behcet Syndrome; Colitis, Ulcerative; Humans; Male; Myelodysplastic Syndromes; U

2022
Alopecia and colon ulcers following azathioprine use in a patient with myasthenia gravis: A case report.
    Medicine, 2022, Aug-19, Volume: 101, Issue:33

    Topics: Adolescent; Alopecia; Azathioprine; Colonic Diseases; Diarrhea; Female; Humans; Myasthenia Gravis; P

2022
Successful multidisciplinary treatment of the rare pathology of vulvar Crohn's disease.
    BMJ case reports, 2023, Oct-16, Volume: 16, Issue:10

    Topics: Azathioprine; Crohn Disease; Dermatitis; Erythema; Female; Granuloma; Humans; Infliximab; Ulcer; Vul

2023
An isolated ulcerated forehead lesion in a 70-year-old man.
    Clinical and experimental dermatology, 2017, Volume: 42, Issue:5

    Topics: Aged; Azathioprine; Diagnosis, Differential; Epstein-Barr Virus Infections; Forehead; Herpesvirus 4,

2017
A rare cause of multiple small bowel ulcers and strictures in a 10-year-old child.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2018, Volume: 29, Issue:1

    Topics: Anemia, Iron-Deficiency; Anti-Inflammatory Agents; Azathioprine; Child; Constriction, Pathologic; En

2018
The great masquerader: Behcet's disease.
    BMJ case reports, 2014, Apr-19, Volume: 2014

    Topics: Abdominal Pain; Adrenal Cortex Hormones; Adult; Azathioprine; Behcet Syndrome; Crohn Disease; Cyclop

2014
Eosinophilic colitis: a rare cause of lower gastrointestinal bleeding in an elderly adult.
    Journal of the American Geriatrics Society, 2014, Volume: 62, Issue:10

    Topics: Aged; Azathioprine; Colitis; Colonoscopy; Eosinophilia; Female; Gastrointestinal Hemorrhage; Glucoco

2014
[Vaginal ulcers in Behçet disease].
    Ginecologia y obstetricia de Mexico, 2008, Volume: 76, Issue:3

    Topics: Adult; Anticoagulants; Azathioprine; Behcet Syndrome; Female; Humans; Immunosuppressive Agents; Oral

2008
Response rates to medical treatments and long-term clinical outcomes of nonsurgical patients with intestinal Behçet disease.
    Journal of clinical gastroenterology, 2010, Volume: 44, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Azathiopr

2010
Efficacy of azathioprine in mild or moderate relapse in Crohn's disease: clinical and endoscopic evaluation.
    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2010, Volume: 22, Issue:1

    Topics: Adult; Azathioprine; Crohn Disease; Endoscopy, Gastrointestinal; Erythrocyte Indices; Female; Humans

2010
A child with simple ulcer of the colon effectively treated with the combination of prednisolone, azathioprine, and pentoxifylline.
    Journal of gastroenterology, 2002, Volume: 37, Issue:9

    Topics: Anti-Inflammatory Agents; Azathioprine; Child; Colonic Diseases; Drug Therapy, Combination; Enzyme I

2002
Crohn's disease with isolated esophagus and gastric involvement.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2004, Volume: 15, Issue:3

    Topics: Adult; Anti-Ulcer Agents; Azathioprine; Biopsy; Crohn Disease; Endoscopy, Gastrointestinal; Esophage

2004
Twelve years experience of juvenile dermatomyositis in North India.
    Rheumatology international, 2006, Volume: 26, Issue:6

    Topics: Adolescent; Age of Onset; Azathioprine; Calcinosis; Child; Child, Preschool; Deglutition Disorders;

2006
Drug management of inflammatory bowel disease.
    Irish medical journal, 1983, Volume: 76, Issue:5

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antidiarrheals; Azathio

1983
Rheumatoid arthritis: treatment with azathioprine (IMURAN (R)). Clinical side-effects and laboratory abnormalities.
    Annals of the rheumatic diseases, 1982, Volume: 41 Suppl 1

    Topics: Adult; Aged; Anorexia; Arthritis, Rheumatoid; Azathioprine; Bacterial Infections; Chemical and Drug

1982
Characteristics of the oral lesions in patients with cutaneous recurrent erythema multiforme.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1995, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Aged; Azathioprine; Erythema Multiforme; Female; Humans; Male; Middle Aged; Mouth

1995
Disseminated histoplasmosis in a haemodialysis patient on immunosuppression after graft failure.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:3

    Topics: Azathioprine; Fatal Outcome; Graft Rejection; Histoplasma; Histoplasmosis; Humans; Immunosuppressive

1996
Use of azathioprine for nongranulomatous ulcerative jejunoileitis.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 1997, Volume: 11, Issue:6

    Topics: Azathioprine; Enteritis; Female; Humans; Ileitis; Immunosuppressive Agents; Jejunal Diseases; Middle

1997
Unusual presentation of cutaneous vasculitis.
    International journal of dermatology, 1998, Volume: 37, Issue:9

    Topics: Anti-Inflammatory Agents; Antimetabolites; Azathioprine; Bacterial Infections; Child; Humans; Male;

1998
The association of upper gastrointestinal ulceration and orthotopic hepatic allotransplantation in the dog.
    Transplantation, 1967, Volume: 5, Issue:4

    Topics: Animals; Azathioprine; Biliary Tract Surgical Procedures; Cholecystectomy; Dactinomycin; Dogs; Gastr

1967
The bleeding cecal ulcer: pathogenesis, angiographic diagnosis, and nonoperative control.
    Surgery, 1972, Volume: 71, Issue:2

    Topics: Adult; Azathioprine; Cecal Diseases; Cecum; Gastrointestinal Hemorrhage; Humans; Immunosuppressive A

1972
Alternate-day single-dose prednisone therapy: a method of reducing steroid toxicity.
    Journal of pediatric surgery, 1972, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Azathioprine; Bacterial Infections; Bone Diseases; Cataract; Child; Child, Presch

1972